Syn1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Syn1
Entrez Gene ID	20964
Full Name	synapsin I
Synonyms	Syn-1,Syn1-S
General protein information	Preferred Names synapsin I Names synapsin-1 truncated synapsin 1-S
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X A1.3\|X 16.37 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_013680.4	NP_038708.3	synapsin-1 isoform a
NM_001110780.1	NP_001104250.1	synapsin-1 isoform b

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SYN1	NP_776616.1
Rattus norvegicus (Norway rat)	Syn1	NP_062006.1
Danio rerio (zebrafish)	syn1	NP_001119909.1
Canis lupus familiaris (dog)	SYN1	XP_003435552.1
Xenopus tropicalis (tropical clawed frog)	LOC100158514	NP_001121423.1
Homo sapiens (human)	SYN1	NP_008881.2
Mus musculus (house mouse)	Syn1	NP_038708.3

Gene Ontology
Bibliography

Related articles in PubMed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.
Ma J, Zhang LQ, He ZX, He XX, Wang YJ, Jian YL, Wang X, Zhang BB, Su C, Lu J, Huang BQ, Zhang Y, Wang GY, Guo WX, Qiu DL, Mei L, Xiong WC, Zheng YW, Zhu XJ
PLoS biology17(10)e3000461(2019 10)

Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites.
Marte A, Russo I, Rebosio C, Valente P, Belluzzi E, Pischedda F, Montani C, Lavarello C, Petretto A, Fedele E, Baldelli P, Benfenati F, Piccoli G, Greggio E, Onofri F
Journal of neurochemistry150(3)264-281(2019 Aug)

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.
Jung H, Park H, Choi Y, Kang H, Lee E, Kweon H, Roh JD, Ellegood J, Choi W, Kang J, Rhim I, Choi SY, Bae M, Kim SG, Lee J, Chung C, Yoo T, Park H, Kim Y, Ha S, Um SM, Mo S, Kwon Y, Mah W, Bae YC, Kim H, Lerch JP, Paik SB, Kim E
Nature neuroscience21(9)1218-1228(2018 09)

Motoneuron Wnts regulate neuromuscular junction development.
Shen C, Li L, Zhao K, Bai L, Wang A, Shu X, Xiao Y, Zhang J, Zhang K, Hui T, Chen W, Zhang B, Hsu W, Xiong WC, Mei L
eLife7(2018 08)

Calcium Influx and Release Cooperatively Regulate AChR Patterning and Motor Axon Outgrowth during Neuromuscular Junction Formation.
Kaplan MM, Sultana N, Benedetti A, Obermair GJ, Linde NF, Papadopoulos S, Dayal A, Grabner M, Flucher BE
Cell reports23(13)3891-3904(2018 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Syn1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Syn1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18142	NM_001110780.1 Latest version!	Mus musculus synapsin I (Syn1), transcript variant b, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu18157	NM_013680.4 Latest version!	Mus musculus synapsin I (Syn1), transcript variant a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$419.30 $599.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Syn1 ( NM_001110780.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001104250.1 Mus musculus synapsin I (Syn1), transcript variant b, mRNA.

Price & Availability↑

CloneID	OMu18142
Clone ID Related Accession (Same CDS sequence)	NM_001110780.1
Accession Version	NM_001110780.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576425600000
Organism	Mus musculus(house mouse)
Product	synapsin-1 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB646141.1, AF085809.1 and BC022954.1. Sequence Note: The sequence AF085809.1 is from a chimeric clone. Only the synapsin I sequence region was propagated into this RefSeq record [Nov/19/2007 RefSeq Staff]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCGAATGGG 
TACATGACAG ACCTGCAGCG CCCGCAACCG CCCCCGCCGC CTCCCTCGGC CGCCAGCCCT 
GGGGCCACGC CCGGCTCCGC GACAGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCTTCTCCAG CAGCCCCTAG TCCTGGGTCC TCGGGGGGCG GCGGCTTCTT CTCGTCGCTG 
TCTAACGCGG TCAAGCAAAC CACAGCAGCC GCAGCCGCCA CCTTCAGCGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAACCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCTGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCTGTGG ACATGGAAGT TCTTCGGAAT GGAGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGAAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGAATC CCCAGTGTAA ACTCTTTGCA TTCTGTCTAC 
AACTTCTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCTA ATCACAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTGGT TGTGAAGATG GGCCACGCAC ATTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATATGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCGGGTA ACTGGAAGAC CAATACAGGT 
TCTGCTATGC TTGAGCAGAT TGCCATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CGCTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGTGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCCGCAGC GGGATGCTTC CCCTGGCAGG GGCTCCCACA GCCAGTCTTC ATCCCCAGGA 
GCCCTGACCT TGGGCCGCCA GACCTCCCAG CAGCCTGCAG GTCCTCCTGC TCAACAACGA 
CCCCCACCCC AGGGAGGCCC TCCACAGCCA GGCCCAGGAC CTCAGCGCCA GGGACCCCCG 
CTGCAGCAGC GCCCACCCCC ACAAGGCCAG CAACATCTTT CTGGCCTTGG ACCGCCAGCT 
GGCAGCCCTC TGCCTCAGCG CCTACCAAGT CCCACCGCAG CACCTCAGCA GTCTGCCTCT 
CAGGCCACAC CAGTGACCCA GGGTCAAGGC CGCCAGTCGC GGCCAGTGGC AGGAGGCCCT 
GGAGCACCTC CAGCAGCGCG CCCACCAGCC TCCCCATCTC CACAGCGTCA GGCGGGGGCC 
CCGCAGGCTA CCCGTCAGGC ATCTATCTCT GGTCCAGCTC CAACGAAGGC CTCAGGAGCC 
CCACCCGGAG GGCAGCAGCG CCAGGGCCCT CCCCAAAAAC CCCCAGGCCC TGCTGGTCCC 
ACTCGTCAGG CCAGTCAGGC AGGTCCCGGA CCTCGCACTG GGCCTCCCAC CACACAGCAG 
CCCCGGCCCA GCGGCCCAGG TCCTGCTGGA CGTCCCGCCA AACCACAGCT GGCCCAGAAA 
CCCAGCCAGG ATGTGCCACC ACCCATCACC GCCGCTGCCG GGGGACCCCC GCACCCCCAG 
CTCAAAGCCA GCCCCTCCCA GGCCCAGCCT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001104250.1
CDS	130..2142
Translation	MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSATASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQPQRDASPGRGSHSQSSSPGALTLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPVTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGAPQATRQASISGPAPTKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPAKPQLAQKPSQDVPPPITAAAGGPPHPQLKASPSQAQP

Target ORF information:

RefSeq Version	NM_001110780.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus synapsin I (Syn1), transcript variant b, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110780.1

ORF Insert Sequence:

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCGAATGGG 
TACATGACAG ACCTGCAGCG CCCGCAACCG CCCCCGCCGC CTCCCTCGGC CGCCAGCCCT 
GGGGCCACGC CCGGCTCCGC GACAGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCTTCTCCAG CAGCCCCTAG TCCTGGGTCC TCGGGGGGCG GCGGCTTCTT CTCGTCGCTG 
TCTAACGCGG TCAAGCAAAC CACAGCAGCC GCAGCCGCCA CCTTCAGCGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAACCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCTGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCTGTGG ACATGGAAGT TCTTCGGAAT GGAGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGAAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGAATC CCCAGTGTAA ACTCTTTGCA TTCTGTCTAC 
AACTTCTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCTA ATCACAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTGGT TGTGAAGATG GGCCACGCAC ATTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATATGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCGGGTA ACTGGAAGAC CAATACAGGT 
TCTGCTATGC TTGAGCAGAT TGCCATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CGCTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGTGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCCGCAGC GGGATGCTTC CCCTGGCAGG GGCTCCCACA GCCAGTCTTC ATCCCCAGGA 
GCCCTGACCT TGGGCCGCCA GACCTCCCAG CAGCCTGCAG GTCCTCCTGC TCAACAACGA 
CCCCCACCCC AGGGAGGCCC TCCACAGCCA GGCCCAGGAC CTCAGCGCCA GGGACCCCCG 
CTGCAGCAGC GCCCACCCCC ACAAGGCCAG CAACATCTTT CTGGCCTTGG ACCGCCAGCT 
GGCAGCCCTC TGCCTCAGCG CCTACCAAGT CCCACCGCAG CACCTCAGCA GTCTGCCTCT 
CAGGCCACAC CAGTGACCCA GGGTCAAGGC CGCCAGTCGC GGCCAGTGGC AGGAGGCCCT 
GGAGCACCTC CAGCAGCGCG CCCACCAGCC TCCCCATCTC CACAGCGTCA GGCGGGGGCC 
CCGCAGGCTA CCCGTCAGGC ATCTATCTCT GGTCCAGCTC CAACGAAGGC CTCAGGAGCC 
CCACCCGGAG GGCAGCAGCG CCAGGGCCCT CCCCAAAAAC CCCCAGGCCC TGCTGGTCCC 
ACTCGTCAGG CCAGTCAGGC AGGTCCCGGA CCTCGCACTG GGCCTCCCAC CACACAGCAG 
CCCCGGCCCA GCGGCCCAGG TCCTGCTGGA CGTCCCGCCA AACCACAGCT GGCCCAGAAA 
CCCAGCCAGG ATGTGCCACC ACCCATCACC GCCGCTGCCG GGGGACCCCC GCACCCCCAG 
CTCAAAGCCA GCCCCTCCCA GGCCCAGCCT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Syn1 ( NM_013680.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038708.3 Mus musculus synapsin I (Syn1), transcript variant a, mRNA.

Price & Availability↑

CloneID	OMu18157
Clone ID Related Accession (Same CDS sequence)	NM_013680.4
Accession Version	NM_013680.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2121bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576425600000
Organism	Mus musculus(house mouse)
Product	synapsin-1 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB646141.1, BC022954.1 and BI730087.1. On Nov 20, 2007 this sequence version replaced NM_013680.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCGAATGGG 
TACATGACAG ACCTGCAGCG CCCGCAACCG CCCCCGCCGC CTCCCTCGGC CGCCAGCCCT 
GGGGCCACGC CCGGCTCCGC GACAGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCTTCTCCAG CAGCCCCTAG TCCTGGGTCC TCGGGGGGCG GCGGCTTCTT CTCGTCGCTG 
TCTAACGCGG TCAAGCAAAC CACAGCAGCC GCAGCCGCCA CCTTCAGCGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAACCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCTGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCTGTGG ACATGGAAGT TCTTCGGAAT GGAGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGAAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGAATC CCCAGTGTAA ACTCTTTGCA TTCTGTCTAC 
AACTTCTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCTA ATCACAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTGGT TGTGAAGATG GGCCACGCAC ATTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATATGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCGGGTA ACTGGAAGAC CAATACAGGT 
TCTGCTATGC TTGAGCAGAT TGCCATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CGCTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGTGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCCGCAGC GGGATGCTTC CCCTGGCAGG GGCTCCCACA GCCAGTCTTC ATCCCCAGGA 
GCCCTGACCT TGGGCCGCCA GACCTCCCAG CAGCCTGCAG GTCCTCCTGC TCAACAACGA 
CCCCCACCCC AGGGAGGCCC TCCACAGCCA GGCCCAGGAC CTCAGCGCCA GGGACCCCCG 
CTGCAGCAGC GCCCACCCCC ACAAGGCCAG CAACATCTTT CTGGCCTTGG ACCGCCAGCT 
GGCAGCCCTC TGCCTCAGCG CCTACCAAGT CCCACCGCAG CACCTCAGCA GTCTGCCTCT 
CAGGCCACAC CAGTGACCCA GGGTCAAGGC CGCCAGTCGC GGCCAGTGGC AGGAGGCCCT 
GGAGCACCTC CAGCAGCGCG CCCACCAGCC TCCCCATCTC CACAGCGTCA GGCGGGGGCC 
CCGCAGGCTA CCCGTCAGGC ATCTATCTCT GGTCCAGCTC CAACGAAGGC CTCAGGAGCC 
CCACCCGGAG GGCAGCAGCG CCAGGGCCCT CCCCAAAAAC CCCCAGGCCC TGCTGGTCCC 
ACTCGTCAGG CCAGTCAGGC AGGTCCCGGA CCTCGCACTG GGCCTCCCAC CACACAGCAG 
CCCCGGCCCA GCGGCCCAGG TCCTGCTGGA CGTCCCGCCA AACCACAGCT GGCCCAGAAA 
CCCAGCCAGG ATGTGCCACC ACCCATCACC GCCGCTGCCG GGGGACCCCC GCACCCCCAG 
CTCAACAAAT CCCAGTCTCT GACCAATGCC TTCAACCTTC CAGAGCCAGC CCCTCCCAGG 
CCCAGCCTTA GCCAGGACGA GGTGAAAGCT GAGACCATCC GCAGCCTGAG GAAGTCTTTC 
GCCAGCCTCT TCTCCGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038708.3
CDS	130..2250
Translation	MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSATASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQPQRDASPGRGSHSQSSSPGALTLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPVTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGAPQATRQASISGPAPTKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPAKPQLAQKPSQDVPPPITAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD

Target ORF information:

RefSeq Version	NM_013680.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus synapsin I (Syn1), transcript variant a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013680.4

ORF Insert Sequence:

ATGAACTACC TGCGGCGCCG CCTGTCGGAC AGCAACTTCA TGGCCAATCT GCCGAATGGG 
TACATGACAG ACCTGCAGCG CCCGCAACCG CCCCCGCCGC CTCCCTCGGC CGCCAGCCCT 
GGGGCCACGC CCGGCTCCGC GACAGCCTCT GCCGAGAGGG CCTCCACAGC TGCTCCAGTG 
GCTTCTCCAG CAGCCCCTAG TCCTGGGTCC TCGGGGGGCG GCGGCTTCTT CTCGTCGCTG 
TCTAACGCGG TCAAGCAAAC CACAGCAGCC GCAGCCGCCA CCTTCAGCGA GCAGGTGGGC 
GGTGGCTCTG GGGGCGCAGG CCGCGGGGGC GCCGCCGCCA GGGTGCTGCT GGTCATCGAC 
GAACCGCACA CCGACTGGGC AAAATACTTC AAAGGGAAGA AGATCCATGG AGAAATTGAC 
ATTAAAGTAG AGCAAGCTGA ATTCTCTGAT CTCAATCTTG TGGCTCATGC CAATGGTGGA 
TTCTCTGTGG ACATGGAAGT TCTTCGGAAT GGAGTCAAAG TTGTGAGGTC TCTGAAGCCA 
GACTTTGTGC TGATCCGCCA GCATGCCTTC AGCATGGCAC GTAATGGAGA CTACCGAAGT 
TTGGTCATTG GGCTGCAGTA TGCTGGAATC CCCAGTGTAA ACTCTTTGCA TTCTGTCTAC 
AACTTCTGTG ACAAACCCTG GGTGTTTGCC CAGATGGTTC GACTACACAA GAAGCTTGGA 
ACAGAGGAAT TCCCTCTGAT TGATCAGACT TTCTATCCTA ATCACAAAGA GATGCTCAGC 
AGCACAACAT ACCCTGTGGT TGTGAAGATG GGCCACGCAC ATTCTGGGAT GGGCAAGGTC 
AAGGTAGACA ACCAACATGA CTTCCAGGAT ATTGCAAGTG TTGTGGCACT GACTAAGACA 
TATGCCACTG CTGAGCCCTT CATTGATGCT AAATATGATG TGCGTGTCCA GAAGATTGGG 
CAGAACTACA AGGCCTACAT GAGGACATCA GTGTCGGGTA ACTGGAAGAC CAATACAGGT 
TCTGCTATGC TTGAGCAGAT TGCCATGTCT GACAGGTACA AGTTGTGGGT AGACACGTGC 
TCAGAGATTT TTGGGGGACT TGACATCTGC GCAGTGGAAG CGCTGCATGG CAAGGACGGA 
AGGGATCACA TTATTGAGGT GGTGGGCTCC TCCATGCCAC TCATTGGTGA TCACCAGGAT 
GAAGACAAGC AGCTCATCGT GGAACTTGTG GTCAACAAGA TGACTCAGGC TCTGCCTCGG 
CAGCCGCAGC GGGATGCTTC CCCTGGCAGG GGCTCCCACA GCCAGTCTTC ATCCCCAGGA 
GCCCTGACCT TGGGCCGCCA GACCTCCCAG CAGCCTGCAG GTCCTCCTGC TCAACAACGA 
CCCCCACCCC AGGGAGGCCC TCCACAGCCA GGCCCAGGAC CTCAGCGCCA GGGACCCCCG 
CTGCAGCAGC GCCCACCCCC ACAAGGCCAG CAACATCTTT CTGGCCTTGG ACCGCCAGCT 
GGCAGCCCTC TGCCTCAGCG CCTACCAAGT CCCACCGCAG CACCTCAGCA GTCTGCCTCT 
CAGGCCACAC CAGTGACCCA GGGTCAAGGC CGCCAGTCGC GGCCAGTGGC AGGAGGCCCT 
GGAGCACCTC CAGCAGCGCG CCCACCAGCC TCCCCATCTC CACAGCGTCA GGCGGGGGCC 
CCGCAGGCTA CCCGTCAGGC ATCTATCTCT GGTCCAGCTC CAACGAAGGC CTCAGGAGCC 
CCACCCGGAG GGCAGCAGCG CCAGGGCCCT CCCCAAAAAC CCCCAGGCCC TGCTGGTCCC 
ACTCGTCAGG CCAGTCAGGC AGGTCCCGGA CCTCGCACTG GGCCTCCCAC CACACAGCAG 
CCCCGGCCCA GCGGCCCAGG TCCTGCTGGA CGTCCCGCCA AACCACAGCT GGCCCAGAAA 
CCCAGCCAGG ATGTGCCACC ACCCATCACC GCCGCTGCCG GGGGACCCCC GCACCCCCAG 
CTCAACAAAT CCCAGTCTCT GACCAATGCC TTCAACCTTC CAGAGCCAGC CCCTCCCAGG 
CCCAGCCTTA GCCAGGACGA GGTGAAAGCT GAGACCATCC GCAGCCTGAG GAAGTCTTTC 
GCCAGCCTCT TCTCCGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.
PLoS biology17(10)e3000461(2019 10)
Ma J,Zhang LQ,He ZX,He XX,Wang YJ,Jian YL,Wang X,Zhang BB,Su C,Lu J,Huang BQ,Zhang Y,Wang GY,Guo WX,Qiu DL,Mei L,Xiong WC,Zheng YW,Zhu XJ

Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites.
Journal of neurochemistry150(3)264-281(2019 Aug)
Marte A,Russo I,Rebosio C,Valente P,Belluzzi E,Pischedda F,Montani C,Lavarello C,Petretto A,Fedele E,Baldelli P,Benfenati F,Piccoli G,Greggio E,Onofri F

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.
Nature neuroscience21(9)1218-1228(2018 09)
Jung H,Park H,Choi Y,Kang H,Lee E,Kweon H,Roh JD,Ellegood J,Choi W,Kang J,Rhim I,Choi SY,Bae M,Kim SG,Lee J,Chung C,Yoo T,Park H,Kim Y,Ha S,Um SM,Mo S,Kwon Y,Mah W,Bae YC,Kim H,Lerch JP,Paik SB,Kim E

Motoneuron Wnts regulate neuromuscular junction development.
eLife7(2018 08)
Shen C,Li L,Zhao K,Bai L,Wang A,Shu X,Xiao Y,Zhang J,Zhang K,Hui T,Chen W,Zhang B,Hsu W,Xiong WC,Mei L

Calcium Influx and Release Cooperatively Regulate AChR Patterning and Motor Axon Outgrowth during Neuromuscular Junction Formation.
Cell reports23(13)3891-3904(2018 06)
Kaplan MM,Sultana N,Benedetti A,Obermair GJ,Linde NF,Papadopoulos S,Dayal A,Grabner M,Flucher BE

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Syn1 cDNA ORF clone, Mus musculus(house mouse)

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