Sftpb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sftpb
Entrez Gene ID	20388
Full Name	surfactant associated protein B
Synonyms	AI562151,SF-B,SP-B,Sftp-3,Sftp3
General protein information	Preferred Names surfactant associated protein B Names pulmonary surfactant-associated protein B pulmonary surfactant-associated proteolipid SPL(Phe)
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 C1\|6 32.27 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001282071.2	NP_001269000.1	pulmonary surfactant-associated protein B isoform 2 precursor
NM_147779.2	NP_680088.1	pulmonary surfactant-associated protein B isoform 1 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SFTPB	XP_005630540.1
Macaca mulatta (Rhesus monkey)	SFTPB	XP_001089841.1
Pan troglodytes (chimpanzee)	SFTPB	XP_001168379.2
Mus musculus (house mouse)	Sftpb	NP_001269000.1
Homo sapiens (human)	SFTPB	NP_000533.3
Xenopus tropicalis (tropical clawed frog)	sftpb	XP_002932589.2
Bos taurus (cattle)	SFTPB	NP_001068779.1
Rattus norvegicus (Norway rat)	Sftpb	NP_620197.1

Gene Ontology
Bibliography

Related articles in PubMed

Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate.
Liberti DC, Zepp JA, Bartoni CA, Liberti KH, Zhou S, Lu M, Morley MP, Morrisey EE
Developmental biology454(2)108-117(2019 Oct)

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling.
Coulombe P, Paliouras GN, Clayton A, Hussainkhel A, Fuller M, Jovanovic V, Dauphinee S, Umlandt P, Xiang P, Kyle AH, Minchinton AI, Humphries RK, Hoodless PA, Parker JDK, Wright JL, Karsan A
Cell reports27(6)1769-1780.e4(2019 May)

Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia.
Chao CM, Moiseenko A, Kosanovic D, Rivetti S, El Agha E, Wilhelm J, Kampschulte M, Yahya F, Ehrhardt H, Zimmer KP, Barreto G, Rizvanov AA, Schermuly RT, Reiss I, Morty RE, Rottier RJ, Bellusci S, Zhang JS
Human molecular genetics28(9)1429-1444(2019 05)

MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencing.
Weng JS, Nakamura T, Moriizumi H, Takano H, Yao R, Takekawa M
Communications biology2227(2019)

Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis.
Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ
Cell death & disease9(11)1118(2018 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sftpb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sftpb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20383	NM_147779.2 Latest version!	Mus musculus surfactant associated protein B (Sftpb), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu20522	NM_001282071.2 Latest version!	Mus musculus surfactant associated protein B (Sftpb), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sftpb ( NM_147779.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_680088.1 Mus musculus surfactant associated protein B (Sftpb), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu20383
Clone ID Related Accession (Same CDS sequence)	NM_147779.2
Accession Version	NM_147779.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577721600000
Organism	Mus musculus(house mouse)
Product	pulmonary surfactant-associated protein B isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC116115.11 and AI894333.1. On Apr 9, 2014 this sequence version replaced NM_147779.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGGCCAAGT CGCACCTACT GCAGTGGCTA CTGCTGCTTC CTACCCTCTG CTGCCCAGGT 
GCAGCTATCA CGTCGGCCTC ATCCCTGGAG TGTGCACAAG GCCCTCAATT CTGGTGCCAA 
AGCCTGGAGC ATGCAGTGCA GTGCAGAGCC CTGGGGCACT GCCTGCAGGA AGTCTGGGGG 
CATGCAGGAG CTAATGACCT GTGCCAAGAG TGTGAGGATA TTGTCCACCT CCTCACAAAG 
ATGACCAAGG AAGATGCTTT CCAGGAAGCA ATCCGGAAGT TCCTGGAACA AGAATGTGAT 
ATCCTTCCCT TGAAGCTGCT TGTGCCCCGG TGTCGCCAAG TGCTTGATGT CTACCTGCCC 
CTGGTTATTG ACTACTTCCA GAGCCAGATT AACCCCAAAG CCATCTGCAA TCATGTGGGC 
CTGTGCCCAC GTGGGCAGGC TAAGCCAGAA CAGAATCCAG GGATGCCGGA TGCCGTTCCA 
AACCCTCTGC TGGACAAGCT GGTCCTCCCT GTGCTGCCAG GAGCCCTCTT GGCAAGGCCT 
GGGCCTCACA CTCAGGACTT CTCTGAGCAA CAGCTCCCCA TTCCCCTGCC CTTCTGCTGG 
CTTTGCAGAA CTCTGATCAA GCGGGTTCAA GCCGTGATCC CCAAGGGTGT GCTGGCTGTG 
GCTGTGTCCC AGGTGTGCCA CGTGGTACCC CTGGTGGTGG GTGGCATCTG CCAGTGCCTG 
GCTGAGCGCT ACACAGTTCT CCTGCTAGAC GCACTGCTGG GCCGTGTGGT GCCCCAGCTA 
GTCTGTGGCC TTGTCCTCCG ATGTTCCACT GAGGATGCCA TGGGCCCTGC CCTCCCTGCT 
GTGGAGCCTC TGATAGAAGA ATGGCCACTA CAGGACACTG AGTGCCATTT CTGCAAGTCT 
GTGATCAACC AGGCCTGGAA CACCAGTGAA CAGGCTATGC CACAGGCAAT GCACCAGGCC 
TGCCTTCGCT TCTGGCTAGA CAGGCAAAAG TGTGAACAGT TTGTGGAACA GCACATGCCC 
CAGCTGCTGG CCCTGGTGCC TAGGAGCCAG GATGCCCACA TCACCTGCCA GGCCCTTGGC 
GTATGTGAGG CCCCGGCTAG CCCTCTGCAG TGCTTCCAAA CCCCACACCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_680088.1
CDS	16..1149
Translation	MAKSHLLQWLLLLPTLCCPGAAITSASSLECAQGPQFWCQSLEHAVQCRALGHCLQEVWGHAGANDLCQECEDIVHLLTKMTKEDAFQEAIRKFLEQECDILPLKLLVPRCRQVLDVYLPLVIDYFQSQINPKAICNHVGLCPRGQAKPEQNPGMPDAVPNPLLDKLVLPVLPGALLARPGPHTQDFSEQQLPIPLPFCWLCRTLIKRVQAVIPKGVLAVAVSQVCHVVPLVVGGICQCLAERYTVLLLDALLGRVVPQLVCGLVLRCSTEDAMGPALPAVEPLIEEWPLQDTECHFCKSVINQAWNTSEQAMPQAMHQACLRFWLDRQKCEQFVEQHMPQLLALVPRSQDAHITCQALGVCEAPASPLQCFQTPHL

Target ORF information:

RefSeq Version	NM_147779.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus surfactant associated protein B (Sftpb), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_147779.2

ORF Insert Sequence:

ATGGCCAAGT CGCACCTACT GCAGTGGCTA CTGCTGCTTC CTACCCTCTG CTGCCCAGGT 
GCAGCTATCA CGTCGGCCTC ATCCCTGGAG TGTGCACAAG GCCCTCAATT CTGGTGCCAA 
AGCCTGGAGC ATGCAGTGCA GTGCAGAGCC CTGGGGCACT GCCTGCAGGA AGTCTGGGGG 
CATGCAGGAG CTAATGACCT GTGCCAAGAG TGTGAGGATA TTGTCCACCT CCTCACAAAG 
ATGACCAAGG AAGATGCTTT CCAGGAAGCA ATCCGGAAGT TCCTGGAACA AGAATGTGAT 
ATCCTTCCCT TGAAGCTGCT TGTGCCCCGG TGTCGCCAAG TGCTTGATGT CTACCTGCCC 
CTGGTTATTG ACTACTTCCA GAGCCAGATT AACCCCAAAG CCATCTGCAA TCATGTGGGC 
CTGTGCCCAC GTGGGCAGGC TAAGCCAGAA CAGAATCCAG GGATGCCGGA TGCCGTTCCA 
AACCCTCTGC TGGACAAGCT GGTCCTCCCT GTGCTGCCAG GAGCCCTCTT GGCAAGGCCT 
GGGCCTCACA CTCAGGACTT CTCTGAGCAA CAGCTCCCCA TTCCCCTGCC CTTCTGCTGG 
CTTTGCAGAA CTCTGATCAA GCGGGTTCAA GCCGTGATCC CCAAGGGTGT GCTGGCTGTG 
GCTGTGTCCC AGGTGTGCCA CGTGGTACCC CTGGTGGTGG GTGGCATCTG CCAGTGCCTG 
GCTGAGCGCT ACACAGTTCT CCTGCTAGAC GCACTGCTGG GCCGTGTGGT GCCCCAGCTA 
GTCTGTGGCC TTGTCCTCCG ATGTTCCACT GAGGATGCCA TGGGCCCTGC CCTCCCTGCT 
GTGGAGCCTC TGATAGAAGA ATGGCCACTA CAGGACACTG AGTGCCATTT CTGCAAGTCT 
GTGATCAACC AGGCCTGGAA CACCAGTGAA CAGGCTATGC CACAGGCAAT GCACCAGGCC 
TGCCTTCGCT TCTGGCTAGA CAGGCAAAAG TGTGAACAGT TTGTGGAACA GCACATGCCC 
CAGCTGCTGG CCCTGGTGCC TAGGAGCCAG GATGCCCACA TCACCTGCCA GGCCCTTGGC 
GTATGTGAGG CCCCGGCTAG CCCTCTGCAG TGCTTCCAAA CCCCACACCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sftpb ( NM_001282071.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001269000.1 Mus musculus surfactant associated protein B (Sftpb), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu20522
Clone ID Related Accession (Same CDS sequence)	NM_001282071.2
Accession Version	NM_001282071.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577808000000
Organism	Mus musculus(house mouse)
Product	pulmonary surfactant-associated protein B isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC116115.11. On Apr 9, 2014 this sequence version replaced NM_001282071.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region and an alternate splice site in the 3' UTR, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGGCCAAGT CGCACCTACT GCAGTGGCTA CTGCTGCTTC CTACCCTCTG CTGCCCAGGT 
GCAGCTATCA CGTCGGCCTC ATCCCTGGAG TGTGCACAAG GCCCTCAATT CTGGTGCCAA 
AGCCTGGAGC ATGCAGTGCA GTGCAGAGCC CTGGGGCACT GCCTGCAGGA AGTCTGGGGG 
CATGCAGGAG CTAATGACCT GTGCCAAGAG TGTGAGGATA TTGTCCACCT CCTCACAAAG 
ATGACCAAGG AAGATGCTTT CCAGGAAGCA ATCCGGAAGT TCCTGGAACA AGAATGTGAT 
ATCCTTCCCT TGAAGCTGCT TGTGCCCCGG TGTCGCCAAG TGCTTGATGT CTACCTGCCC 
CTGGTTATTG ACTACTTCCA GAGCCAGATT AACCCCAAAG CCATCTGCAA TCATGTGGGC 
CTGTGCCCAC GTGGGCAGGC TAAGCCAGAA CAGAATCCAG GGATGCCGGA TGCCGTTCCA 
AACCCTCTGC TGGACAAGCT GGTCCTCCCT GTGCTGCCAG GAGCCCTCTT GGCAAGGCCT 
GGGCCTCACA CTCAGGACTT CTCTGAGCAA CAGCTCCCCA TTCCCCTGCC CTTCTGCTGG 
CTTTGCAGAA CTCTGATCAA GCGGGTTCAA GCCGTGATCC CCAAGTGCCT GGCTGAGCGC 
TACACAGTTC TCCTGCTAGA CGCACTGCTG GGCCGTGTGG TGCCCCAGCT AGTCTGTGGC 
CTTGTCCTCC GATGTTCCAC TGAGGATGCC ATGGGCCCTG CCCTCCCTGC TGTGGAGCCT 
CTGATAGAAG AATGGCCACT ACAGGACACT GAGTGCCATT TCTGCAAGTC TGTGATCAAC 
CAGGCCTGGA ACACCAGTGA ACAGGCTATG CCACAGGCAA TGCACCAGGC CTGCCTTCGC 
TTCTGGCTAG ACAGGCAAAA GTGTGAACAG TTTGTGGAAC AGCACATGCC CCAGCTGCTG 
GCCCTGGTGC CTAGGAGCCA GGATGCCCAC ATCACCTGCC AGGCCCTTGG CGTATGTGAG 
GCCCCGGCTA GCCCTCTGCA GTGCTTCCAA ACCCCACACC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269000.1
CDS	16..1080
Translation	MAKSHLLQWLLLLPTLCCPGAAITSASSLECAQGPQFWCQSLEHAVQCRALGHCLQEVWGHAGANDLCQECEDIVHLLTKMTKEDAFQEAIRKFLEQECDILPLKLLVPRCRQVLDVYLPLVIDYFQSQINPKAICNHVGLCPRGQAKPEQNPGMPDAVPNPLLDKLVLPVLPGALLARPGPHTQDFSEQQLPIPLPFCWLCRTLIKRVQAVIPKCLAERYTVLLLDALLGRVVPQLVCGLVLRCSTEDAMGPALPAVEPLIEEWPLQDTECHFCKSVINQAWNTSEQAMPQAMHQACLRFWLDRQKCEQFVEQHMPQLLALVPRSQDAHITCQALGVCEAPASPLQCFQTPHL

Target ORF information:

RefSeq Version	NM_001282071.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus surfactant associated protein B (Sftpb), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282071.2

ORF Insert Sequence:

ATGGCCAAGT CGCACCTACT GCAGTGGCTA CTGCTGCTTC CTACCCTCTG CTGCCCAGGT 
GCAGCTATCA CGTCGGCCTC ATCCCTGGAG TGTGCACAAG GCCCTCAATT CTGGTGCCAA 
AGCCTGGAGC ATGCAGTGCA GTGCAGAGCC CTGGGGCACT GCCTGCAGGA AGTCTGGGGG 
CATGCAGGAG CTAATGACCT GTGCCAAGAG TGTGAGGATA TTGTCCACCT CCTCACAAAG 
ATGACCAAGG AAGATGCTTT CCAGGAAGCA ATCCGGAAGT TCCTGGAACA AGAATGTGAT 
ATCCTTCCCT TGAAGCTGCT TGTGCCCCGG TGTCGCCAAG TGCTTGATGT CTACCTGCCC 
CTGGTTATTG ACTACTTCCA GAGCCAGATT AACCCCAAAG CCATCTGCAA TCATGTGGGC 
CTGTGCCCAC GTGGGCAGGC TAAGCCAGAA CAGAATCCAG GGATGCCGGA TGCCGTTCCA 
AACCCTCTGC TGGACAAGCT GGTCCTCCCT GTGCTGCCAG GAGCCCTCTT GGCAAGGCCT 
GGGCCTCACA CTCAGGACTT CTCTGAGCAA CAGCTCCCCA TTCCCCTGCC CTTCTGCTGG 
CTTTGCAGAA CTCTGATCAA GCGGGTTCAA GCCGTGATCC CCAAGTGCCT GGCTGAGCGC 
TACACAGTTC TCCTGCTAGA CGCACTGCTG GGCCGTGTGG TGCCCCAGCT AGTCTGTGGC 
CTTGTCCTCC GATGTTCCAC TGAGGATGCC ATGGGCCCTG CCCTCCCTGC TGTGGAGCCT 
CTGATAGAAG AATGGCCACT ACAGGACACT GAGTGCCATT TCTGCAAGTC TGTGATCAAC 
CAGGCCTGGA ACACCAGTGA ACAGGCTATG CCACAGGCAA TGCACCAGGC CTGCCTTCGC 
TTCTGGCTAG ACAGGCAAAA GTGTGAACAG TTTGTGGAAC AGCACATGCC CCAGCTGCTG 
GCCCTGGTGC CTAGGAGCCA GGATGCCCAC ATCACCTGCC AGGCCCTTGG CGTATGTGAG 
GCCCCGGCTA GCCCTCTGCA GTGCTTCCAA ACCCCACACC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate.
Developmental biology454(2)108-117(2019 Oct)
Liberti DC,Zepp JA,Bartoni CA,Liberti KH,Zhou S,Lu M,Morley MP,Morrisey EE

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling.
Cell reports27(6)1769-1780.e4(2019 May)
Coulombe P,Paliouras GN,Clayton A,Hussainkhel A,Fuller M,Jovanovic V,Dauphinee S,Umlandt P,Xiang P,Kyle AH,Minchinton AI,Humphries RK,Hoodless PA,Parker JDK,Wright JL,Karsan A

Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia.
Human molecular genetics28(9)1429-1444(2019 05)
Chao CM,Moiseenko A,Kosanovic D,Rivetti S,El Agha E,Wilhelm J,Kampschulte M,Yahya F,Ehrhardt H,Zimmer KP,Barreto G,Rizvanov AA,Schermuly RT,Reiss I,Morty RE,Rottier RJ,Bellusci S,Zhang JS

MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencing.
Communications biology2227(2019)
Weng JS,Nakamura T,Moriizumi H,Takano H,Yao R,Takekawa M

Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis.
Cell death & disease9(11)1118(2018 11)
Moon S,Im SK,Kim N,Youn H,Park UH,Kim JY,Kim AR,An SJ,Kim JH,Sun W,Hwang JT,Kim EJ,Um SJ

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Sftpb cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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