Ell2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ell2
Entrez Gene ID	192657
Full Name	elongation factor RNA polymerase II 2
General protein information	Preferred Names elongation factor RNA polymerase II 2 Names RNA polymerase II elongation factor ELL2 ELL-related RNA polymerase II, elongation factor eleven-nineteen lysine-rich leukemia gene 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_138953.2	NP_620403.2	RNA polymerase II elongation factor ELL2

Pathways from BioSystems

Homologies

Homo sapiens (human)	ELL2	NP_036213.2
Pan troglodytes (chimpanzee)	ELL2	XP_517646.2
Mus musculus (house mouse)	Ell2	NP_620403.2
Xenopus tropicalis (tropical clawed frog)	ell2	XP_002933477.1
Bos taurus (cattle)	ELL2	NP_001178075.1
Rattus norvegicus (Norway rat)	Ell2	XP_226624.5
Macaca mulatta (Rhesus monkey)	ELL2	XP_001094059.1
Canis lupus familiaris (dog)	ELL2	XP_546016.2
Gallus gallus (chicken)	ELL2	XP_004949437.1
Danio rerio (zebrafish)	ell2	NP_001077281.2

Gene Ontology
Bibliography

Related articles in PubMed

RNA Splicing in the Transition from B Cells to Antibody-Secreting Cells: The Influences of ELL2, Small Nuclear RNA, and Endoplasmic Reticulum Stress.
Nelson AM, Carew NT, Smith SM, Milcarek C
Journal of immunology (Baltimore, Md. : 1950)201(10)3073-3083(2018 11)

Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia.
Pascal LE, Masoodi KZ, Liu J, Qiu X, Song Q, Wang Y, Zang Y, Yang T, Wang Y, Rigatti LH, Chandran U, Colli LM, Vencio RZN, Lu Y, Zhang J, Wang Z
The Journal of endocrinology235(2)123-136(2017 Nov)

Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes.
Sharma S, Wang J, Cortes Gomez E, Taggart RT, Baysal BE
Human molecular genetics26(7)1328-1339(2017 04)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

A gene expression resource generated by genome-wide lacZ profiling in the mouse.
Tuck E, Estabel J, Oellrich A, Maguire AK, Adissu HA, Souter L, Siragher E, Lillistone C, Green AL, Wardle-Jones H, Carragher DM, Karp NA, Smedley D, Adams NC, , Bussell JN, Adams DJ, Ramírez-Solis R, Steel KP, Galli A, White JK
Disease models & mechanisms8(11)1467-78(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ell2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ell2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10920	NM_138953.2 Latest version!	Mus musculus elongation factor RNA polymerase II 2 (Ell2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ell2 ( NM_138953.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_620403.2 Mus musculus elongation factor RNA polymerase II 2 (Ell2), mRNA.

Price & Availability↑

CloneID	OMu10920
Clone ID Related Accession (Same CDS sequence)	NM_138953.2
Accession Version	NM_138953.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1920bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	RNA polymerase II elongation factor ELL2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CT025556.12, AK145868.1 and BE133837.1. On or before Oct 19, 2006 this sequence version replaced XM_484289.4, XM_898358.2, XM_898363.2, XM_898369.2, XM_911428.2, XM_922000.2, XM_922005.2, XM_922010.2, XM_992847.1, XM_992820.1, XM_992784.1, XM_992760.1, NM_138953.1. ##Evidence-Data-START## Transcript exon combination :: AK156164.1, AK145868.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG GGGGGGCTGC GGGACTGCGG GAGGAGCAGC GGTACGGGCT GGCGTGCGGG 
CGGCTGGGGC AGGACAACAT CACCGTGCTG CATGTGAAGC TCACCGAGAC GGCGATCCGG 
GCGCTGGAGA CTTACCAGAG CCACAAGAAT TTAATTCCTT TTAGACCTTC AATTCAGTTC 
CAAGGACTCC AAGGGCTTAT GAAAATTCCC AAAAATGATC CCTTCAATGA AGTCCAGAAC 
TTTAACTTCT ACTTGTCAAA CGTGGGAAGA GATAATCCTC AGGGCAGCTT TGACTGCATC 
CAGCAAACAC TCTCTAGCTC TGGAGCCTCC CAGCTCAATT GCCTGGGATT TATACAAGAT 
AAAATTACAG TGTGTGCAAC AAATGATTCC TATCAGATGA CGCGAGAAAG AATGACCCAG 
GCAGAGGAGG AATCCCGTAA TCGAAGCACA AAAGTTATCA AACCCGGTGG ACCATATGTA 
GGGAAAAGAG TGCAAATTCG TAAAGCTCCT CAAGCCATCT CGGACACAGT GCCTGAGAGG 
AAAAGGTCAA CGCCCATGAA CCCTGCAAAT ACAATTCGAA AGATGCATAG TGGCAACAGT 
GTCTCTCAGA GGCCATACAG GGACAGGGTC ATCCATTTAC TGGCACTAAA AGCCTACAAG 
AAACCTGAGC TGCTTGCTCG ACTGCAGAAA GATGGTGTCA ATCAAAAAGA CAAGAACTCC 
TTGGGAGCAA TTCTGCAACA GGTGGCCAAT CTGAATCCTA AGGACCTCTC CTATACTTTA 
AAGGATTATG TATTTAAGGA GCTCCAGCGA GACTGGCCAG GTTACAGTGA GACAGACAGA 
CAGACATTGG ATTTGGTGCT CTCTAGAAAA CTAAATCCAT CTCAGAATGC TAGCACCAGC 
CGGTCAGAGT CTCCCCTGTG TTCCAGCAAA GACGCTGCCT CATCTCCTCA GAAACGACCT 
TTGGATTCAG ATTTCATTGA TCCTTTAATG AACAAAAAAG CTCGAATATC TCACCTAACA 
AACAGAGTCC CACCGACATT AAATGGTTAT TTGAATCCCA CCAGTGAAAA ATCTTGTGCA 
GGCCTCCTAC CACCCCCTGC AGCTGCTGCC ATCCCCACCC TCTCGCCGCT GCCTTCAACC 
CACCTGCCTG TCTCCAATCC TCCTCAGACT GTAAATTCCA ACTCCAATTC CCCTAGCACT 
CCAGAAGGCC TGGGGACTCA AGACCTGCCT GTTGACAGTT TTAGTCAAAA TGGTAGCATC 
TTTGAGGACC AGCAAGAAAA ATATACCTCA AGGACTTGTC TGGAAACATT ACCCCCCAGC 
TCAGCTCTGC TAAAGTGTCC AAAGCCCATG GAAGAAGAGC ATCCAGTGTC TCACAAAAAG 
TCCAAAAAGA AGTCTAAAAA ACACAAGGAA AAGGACCAAA TAAAGAAACT TGACATTGAG 
ACCATGGAGG AGAAGGAGGA AGACCTTCAG AGAGAAGAAA CTGCCAAGCT GAGTAATGCC 
AGTCCAAATC CCAATGAAGG AGTTAAAGAA GGGTGCACAG CCTCCATGGA GCCTTCTTCA 
GCACTTGAAC TCCCAGATTA TTTGATAAAA TATATTGCTA TTGTCTCTTA TGAGCAACGC 
CAGAATTACA AGGATGACTT CAATGCTGAG TATGATGAAT ACAGAGCTTT GCATGCAAGG 
ATGGAGACTG TAGCCAGGAG ATTTATTAAA CTGGATGCAC AACGAAAACG CCTTTCTCCG 
GGTTCAAAAG AGTACCAGAA TGTTCATGAA GAAGTCTTAC AGGAATATCA GAAGATCAAG 
CAGTCCAGTC CCAATTACCA TGAAGAAAAA TACAGATGTG AATATCTTCA TAACAAGCTG 
GCTCACATCA AAAGACTAAT AGGTGAATTT GACCAACAGC AAGCAGAGTC ATGGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620403.2
CDS	168..2087
Translation	MAAGGAAGLREEQRYGLACGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLQGLMKIPKNDPFNEVQNFNFYLSNVGRDNPQGSFDCIQQTLSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAISDTVPERKRSTPMNPANTIRKMHSGNSVSQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNPKDLSYTLKDYVFKELQRDWPGYSETDRQTLDLVLSRKLNPSQNASTSRSESPLCSSKDAASSPQKRPLDSDFIDPLMNKKARISHLTNRVPPTLNGYLNPTSEKSCAGLLPPPAAAAIPTLSPLPSTHLPVSNPPQTVNSNSNSPSTPEGLGTQDLPVDSFSQNGSIFEDQQEKYTSRTCLETLPPSSALLKCPKPMEEEHPVSHKKSKKKSKKHKEKDQIKKLDIETMEEKEEDLQREETAKLSNASPNPNEGVKEGCTASMEPSSALELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWH

Target ORF information:

RefSeq Version	NM_138953.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus elongation factor RNA polymerase II 2 (Ell2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138953.2

ORF Insert Sequence:

ATGGCGGCGG GGGGGGCTGC GGGACTGCGG GAGGAGCAGC GGTACGGGCT GGCGTGCGGG 
CGGCTGGGGC AGGACAACAT CACCGTGCTG CATGTGAAGC TCACCGAGAC GGCGATCCGG 
GCGCTGGAGA CTTACCAGAG CCACAAGAAT TTAATTCCTT TTAGACCTTC AATTCAGTTC 
CAAGGACTCC AAGGGCTTAT GAAAATTCCC AAAAATGATC CCTTCAATGA AGTCCAGAAC 
TTTAACTTCT ACTTGTCAAA CGTGGGAAGA GATAATCCTC AGGGCAGCTT TGACTGCATC 
CAGCAAACAC TCTCTAGCTC TGGAGCCTCC CAGCTCAATT GCCTGGGATT TATACAAGAT 
AAAATTACAG TGTGTGCAAC AAATGATTCC TATCAGATGA CGCGAGAAAG AATGACCCAG 
GCAGAGGAGG AATCCCGTAA TCGAAGCACA AAAGTTATCA AACCCGGTGG ACCATATGTA 
GGGAAAAGAG TGCAAATTCG TAAAGCTCCT CAAGCCATCT CGGACACAGT GCCTGAGAGG 
AAAAGGTCAA CGCCCATGAA CCCTGCAAAT ACAATTCGAA AGATGCATAG TGGCAACAGT 
GTCTCTCAGA GGCCATACAG GGACAGGGTC ATCCATTTAC TGGCACTAAA AGCCTACAAG 
AAACCTGAGC TGCTTGCTCG ACTGCAGAAA GATGGTGTCA ATCAAAAAGA CAAGAACTCC 
TTGGGAGCAA TTCTGCAACA GGTGGCCAAT CTGAATCCTA AGGACCTCTC CTATACTTTA 
AAGGATTATG TATTTAAGGA GCTCCAGCGA GACTGGCCAG GTTACAGTGA GACAGACAGA 
CAGACATTGG ATTTGGTGCT CTCTAGAAAA CTAAATCCAT CTCAGAATGC TAGCACCAGC 
CGGTCAGAGT CTCCCCTGTG TTCCAGCAAA GACGCTGCCT CATCTCCTCA GAAACGACCT 
TTGGATTCAG ATTTCATTGA TCCTTTAATG AACAAAAAAG CTCGAATATC TCACCTAACA 
AACAGAGTCC CACCGACATT AAATGGTTAT TTGAATCCCA CCAGTGAAAA ATCTTGTGCA 
GGCCTCCTAC CACCCCCTGC AGCTGCTGCC ATCCCCACCC TCTCGCCGCT GCCTTCAACC 
CACCTGCCTG TCTCCAATCC TCCTCAGACT GTAAATTCCA ACTCCAATTC CCCTAGCACT 
CCAGAAGGCC TGGGGACTCA AGACCTGCCT GTTGACAGTT TTAGTCAAAA TGGTAGCATC 
TTTGAGGACC AGCAAGAAAA ATATACCTCA AGGACTTGTC TGGAAACATT ACCCCCCAGC 
TCAGCTCTGC TAAAGTGTCC AAAGCCCATG GAAGAAGAGC ATCCAGTGTC TCACAAAAAG 
TCCAAAAAGA AGTCTAAAAA ACACAAGGAA AAGGACCAAA TAAAGAAACT TGACATTGAG 
ACCATGGAGG AGAAGGAGGA AGACCTTCAG AGAGAAGAAA CTGCCAAGCT GAGTAATGCC 
AGTCCAAATC CCAATGAAGG AGTTAAAGAA GGGTGCACAG CCTCCATGGA GCCTTCTTCA 
GCACTTGAAC TCCCAGATTA TTTGATAAAA TATATTGCTA TTGTCTCTTA TGAGCAACGC 
CAGAATTACA AGGATGACTT CAATGCTGAG TATGATGAAT ACAGAGCTTT GCATGCAAGG 
ATGGAGACTG TAGCCAGGAG ATTTATTAAA CTGGATGCAC AACGAAAACG CCTTTCTCCG 
GGTTCAAAAG AGTACCAGAA TGTTCATGAA GAAGTCTTAC AGGAATATCA GAAGATCAAG 
CAGTCCAGTC CCAATTACCA TGAAGAAAAA TACAGATGTG AATATCTTCA TAACAAGCTG 
GCTCACATCA AAAGACTAAT AGGTGAATTT GACCAACAGC AAGCAGAGTC ATGGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RNA Splicing in the Transition from B Cells to Antibody-Secreting Cells: The Influences of ELL2, Small Nuclear RNA, and Endoplasmic Reticulum Stress.
Journal of immunology (Baltimore, Md. : 1950)201(10)3073-3083(2018 11)
Nelson AM,Carew NT,Smith SM,Milcarek C

Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia.
The Journal of endocrinology235(2)123-136(2017 Nov)
Pascal LE,Masoodi KZ,Liu J,Qiu X,Song Q,Wang Y,Zang Y,Yang T,Wang Y,Rigatti LH,Chandran U,Colli LM,Vencio RZN,Lu Y,Zhang J,Wang Z

Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes.
Human molecular genetics26(7)1328-1339(2017 04)
Sharma S,Wang J,Cortes Gomez E,Taggart RT,Baysal BE

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

A gene expression resource generated by genome-wide lacZ profiling in the mouse.
Disease models & mechanisms8(11)1467-78(2015 Nov)
Tuck E,Estabel J,Oellrich A,Maguire AK,Adissu HA,Souter L,Siragher E,Lillistone C,Green AL,Wardle-Jones H,Carragher DM,Karp NA,Smedley D,Adams NC,,Bussell JN,Adams DJ,Ramírez-Solis R,Steel KP,Galli A,White JK

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Ell2 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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