Psmc3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Psmc3
Entrez Gene ID	19182
Full Name	proteasome (prosome, macropain) 26S subunit, ATPase 3
Synonyms	TBP-1
General protein information	Preferred Names proteasome (prosome, macropain) 26S subunit, ATPase 3 Names 26S proteasome regulatory subunit 6A 26S protease regulatory subunit 6A 26S proteasome AAA-ATPase subunit RPT5 TAT-binding protein 1 Tat binding protein 1 proteasome 26S subunit ATPase 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 E1\|2 50.44 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008948.2	NP_032974.2	26S proteasome regulatory subunit 6A

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os06g0173100	NP_001056944.1
Canis lupus familiaris (dog)	PSMC3	XP_533187.3
Bos taurus (cattle)	PSMC3	NP_001179113.2
Mus musculus (house mouse)	Psmc3	NP_032974.2
Caenorhabditis elegans (roundworm)	rpt-5	NP_491672.1
Eremothecium gossypii	AGOS_AER254W	NP_985111.2
Homo sapiens (human)	PSMC3	NP_002795.2
Arabidopsis thaliana (thale cress)	RPT5A	NP_187204.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000616	XP_310465.3
Oryza sativa (rice)	Os02g0803700	NP_001048428.1
Saccharomyces cerevisiae (baker's yeast)	RPT5	NP_014760.3
Magnaporthe oryzae (rice blast fungus)	MGG_12925	XP_003712713.1
Pan troglodytes (chimpanzee)	PSMC3	XP_508413.3
Macaca mulatta (Rhesus monkey)	PSMC3	XP_001106497.1
Rattus norvegicus (Norway rat)	Psmc3	NP_113783.1
Gallus gallus (chicken)	PSMC3	NP_001026361.1
Drosophila melanogaster (fruit fly)	Tbp-1	NP_524464.1
Kluyveromyces lactis	KLLA0E21209g	XP_454909.1
Danio rerio (zebrafish)	psmc3	NP_001002064.1
Arabidopsis thaliana (thale cress)	RPT5B	NP_172384.1
Xenopus tropicalis (tropical clawed frog)	psmc3	NP_001006786.1
Neurospora crassa	NCU04414	XP_957491.2
Schizosaccharomyces pombe (fission yeast)	rpt5	XP_001713083.1

Gene Ontology
Bibliography

Related articles in PubMed

TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions.
Lukic Z, Hausmann S, Sebastian S, Rucci J, Sastri J, Robia SL, Luban J, Campbell EM
Retrovirology893(2011 Nov)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

Mapping the murine cardiac 26S proteasome complexes.
Gomes AV, Zong C, Edmondson RD, Li X, Stefani E, Zhang J, Jones RC, Thyparambil S, Wang GW, Qiao X, Bardag-Gorce F, Ping P
Circulation research99(4)362-71(2006 Aug)

SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation.
Binato R, Alvarez Martinez CE, Pizzatti L, Robert B, Abdelhay E
The Biochemical journal393(Pt 1)141-50(2006 Jan)

Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.
Corn PG, McDonald ER 3rd, Herman JG, El-Deiry WS
Nature genetics35(3)229-37(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Psmc3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psmc3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03147	NM_008948.2 Latest version!	Mus musculus proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Psmc3 ( NM_008948.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032974.2 Mus musculus proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), mRNA.

Price & Availability↑

CloneID	OMu03147
Clone ID Related Accession (Same CDS sequence)	NM_008948.2
Accession Version	NM_008948.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	26S proteasome regulatory subunit 6A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX201527.1, AK167002.1 and BE989849.1. On Apr 29, 2009 this sequence version replaced NM_008948.1. ##Evidence-Data-START## Transcript exon combination :: AK167061.1, AK167002.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGAAA TGAATCTGCT GCCGACGCCC GAGAGTCCAG TGACTCGGCA GGAGAAGATG 
GCGACCGTGT GGGATGAAGC TGAGCAAGAT GGCATTGGGG AGGAGGTGCT CAAGATGTCC 
ACGGAAGAGA TTGTCCAGCG CACACGGCTG TTAGACAGCG AGATCAAGAT CATGAAGAGT 
GAAGTATTGC GAGTCACCCA TGAACTCCAA GCCATGAAAG ACAAAATCAA AGAGAACAGT 
GAGAAAATCA AAGTGAACAA AACCCTGCCG TACCTTGTCT CCAATGTCAT CGAGTTGCTG 
GACGTTGACC CCAATGACCA GGAGGAGGAT GGTGCCAACA TTGACCTGGA CTCTCAGAGG 
AAGGGCAAGT GTGCGGTGAT CAAAACTTCT ACCCGACAGA CATACTTCCT GCCAGTGATT 
GGGTTGGTGG ATGCAGAAAA GCTGAAGCCA GGAGACCTGG TGGGTGTGAA CAAAGACTCC 
TATCTGATCC TGGAGACCCT GCCCACTGAA TATGACTCTC GGGTGAAGGC CATGGAGGTG 
GACGAGCGGC CCACGGAGCA ATACAGTGAC ATCGGGGGCC TGGACAAGCA GATCCAGGAG 
CTGGTGGAAG CCATTGTCTT GCCTATGAAC CACAAAGAGA AGTTTGAGAA CTTGGGTATC 
CAGCCCCCAA AAGGAGTGCT GATGTATGGG CCGCCTGGAA CAGGGAAGAC TCTGCTTGCC 
CGAGCCTGTG CTGCTCAGAC CAAGGCCACC TTCTTGAAGC TGGCAGGCCC TCAGCTGGTA 
CAGATGTTTA TTGGAGATGG CGCCAAGCTG GTCCGTGATG CTTTTGCCCT GGCCAAGGAG 
AAGGCACCAT CTATTATTTT CATAGACGAA TTGGATGCCA TTGGTACCAA ACGCTTCGAC 
AGTGAAAAGG CAGGAGACCG AGAGGTGCAG AGGACCATGC TGGAGCTACT GAACCAGCTG 
GACGGCTTTC AGCCCAACAC TCAAGTGAAG GTAATTGCAG CCACTAACAG GGTGGACATC 
CTGGATCCAG CCCTGCTGCG CTCAGGCCGC CTAGACCGCA AGATTGAGTT TCCAATGCCC 
AACGAGGAGG CCAGAGCCAG AATCATGCAG ATCCACTCAC GGAAGATGAA TGTCAGTCCT 
GATGTGAACT ATGAAGAGCT GGCTCGGTGC ACTGATGACT TCAATGGAGC CCAGTGCAAG 
GCCGTGTGTG TGGAGGCGGG TATGATCGCA TTGCGCAGGG GAGCCACGGA ACTCACTCAT 
GAGGACTACA TGGAGGGCAT CCTGGAGGTT CAGGCCAAGA AGAAAGCCAA CCTACAATAC 
TATGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032974.2
CDS	233..1561
Translation	MQEMNLLPTPESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIVQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA

Target ORF information:

RefSeq Version	NM_008948.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008948.2

ORF Insert Sequence:

ATGCAGGAAA TGAATCTGCT GCCGACGCCC GAGAGTCCAG TGACTCGGCA GGAGAAGATG 
GCGACCGTGT GGGATGAAGC TGAGCAAGAT GGCATTGGGG AGGAGGTGCT CAAGATGTCC 
ACGGAAGAGA TTGTCCAGCG CACACGGCTG TTAGACAGCG AGATCAAGAT CATGAAGAGT 
GAAGTATTGC GAGTCACCCA TGAACTCCAA GCCATGAAAG ACAAAATCAA AGAGAACAGT 
GAGAAAATCA AAGTGAACAA AACCCTGCCG TACCTTGTCT CCAATGTCAT CGAGTTGCTG 
GACGTTGACC CCAATGACCA GGAGGAGGAT GGTGCCAACA TTGACCTGGA CTCTCAGAGG 
AAGGGCAAGT GTGCGGTGAT CAAAACTTCT ACCCGACAGA CATACTTCCT GCCAGTGATT 
GGGTTGGTGG ATGCAGAAAA GCTGAAGCCA GGAGACCTGG TGGGTGTGAA CAAAGACTCC 
TATCTGATCC TGGAGACCCT GCCCACTGAA TATGACTCTC GGGTGAAGGC CATGGAGGTG 
GACGAGCGGC CCACGGAGCA ATACAGTGAC ATCGGGGGCC TGGACAAGCA GATCCAGGAG 
CTGGTGGAAG CCATTGTCTT GCCTATGAAC CACAAAGAGA AGTTTGAGAA CTTGGGTATC 
CAGCCCCCAA AAGGAGTGCT GATGTATGGG CCGCCTGGAA CAGGGAAGAC TCTGCTTGCC 
CGAGCCTGTG CTGCTCAGAC CAAGGCCACC TTCTTGAAGC TGGCAGGCCC TCAGCTGGTA 
CAGATGTTTA TTGGAGATGG CGCCAAGCTG GTCCGTGATG CTTTTGCCCT GGCCAAGGAG 
AAGGCACCAT CTATTATTTT CATAGACGAA TTGGATGCCA TTGGTACCAA ACGCTTCGAC 
AGTGAAAAGG CAGGAGACCG AGAGGTGCAG AGGACCATGC TGGAGCTACT GAACCAGCTG 
GACGGCTTTC AGCCCAACAC TCAAGTGAAG GTAATTGCAG CCACTAACAG GGTGGACATC 
CTGGATCCAG CCCTGCTGCG CTCAGGCCGC CTAGACCGCA AGATTGAGTT TCCAATGCCC 
AACGAGGAGG CCAGAGCCAG AATCATGCAG ATCCACTCAC GGAAGATGAA TGTCAGTCCT 
GATGTGAACT ATGAAGAGCT GGCTCGGTGC ACTGATGACT TCAATGGAGC CCAGTGCAAG 
GCCGTGTGTG TGGAGGCGGG TATGATCGCA TTGCGCAGGG GAGCCACGGA ACTCACTCAT 
GAGGACTACA TGGAGGGCAT CCTGGAGGTT CAGGCCAAGA AGAAAGCCAA CCTACAATAC 
TATGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions.
Retrovirology893(2011 Nov)
Lukic Z,Hausmann S,Sebastian S,Rucci J,Sastri J,Robia SL,Luban J,Campbell EM

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

Mapping the murine cardiac 26S proteasome complexes.
Circulation research99(4)362-71(2006 Aug)
Gomes AV,Zong C,Edmondson RD,Li X,Stefani E,Zhang J,Jones RC,Thyparambil S,Wang GW,Qiao X,Bardag-Gorce F,Ping P

SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation.
The Biochemical journal393(Pt 1)141-50(2006 Jan)
Binato R,Alvarez Martinez CE,Pizzatti L,Robert B,Abdelhay E

Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.
Nature genetics35(3)229-37(2003 Nov)
Corn PG,McDonald ER 3rd,Herman JG,El-Deiry WS

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Psmc3 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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