| Gene Symbol | Bpifa1 |
| Entrez Gene ID | 18843 |
| Full Name | BPI fold containing family A, member 1 |
| Synonyms | LUNX,NASG,Plunc,SPLUNC1,SPURT |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Bpifa1 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Bpifa1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bpifa1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu20056 Clone ID Related Accession (Same CDS sequence) NM_011126.3 Accession Version NM_011126.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 837bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577462400000 Organism Mus musculus(house mouse) Product BPI fold-containing family A member 1 precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY121014.1 and BC054375.1. On Apr 28, 2009 this sequence version replaced NM_011126.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U69172.1, BC054375.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849387 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781ATGTTTCTAG TTGGGAGCCT CGTTGTCCTC TGTGGGCTGC TGGCCCACAG CACAGCACAG
CTGGCAGGCT TGCCATTGCC CCTGGGCCAG GGTCCACCCT TGCCACTGAA CCAGGGCCCA
CCGTTGCCAC TGAACCAGGG CCAGCTGTTG CCCCTGGCTC AGGGTCTGCC TTTGGCTGTA
AGCCCAGCAC TGCCTTCAAA TCCCACAGAT CTTCTTGCTG GAAAATTCAC AGATGCTCTC
AGCGGTGGCC TGCTGTCTGG GGGGCTGCTG GGCATTTTGG AAAATATTCC ACTCCTGGAT
GTTATAAAGT CTGGAGGAGG CAATTCTAAT GGCCTTGTTG GGGGCCTGCT GGGAAAACTG
ACGTCATCAG TTCCTCTCCT GAACAACATC CTCGACATAA AAATCACTGA TCCGCAGCTG
CTAGAACTTG GTCTTGTGCA GAGTCCTGAT GGCCATCGTC TCTATGTCAC CATCCCTCTG
GGCTTGACAC TCAACGTAAA TATGCCCGTA GTTGGAAGTC TTTTGCAATT GGCTGTGAAG
CTGAACATTA CTGCAGAAGT CTTAGCCGTG AAAGACAATC AGGGGAGGAT TCATCTGGTT
CTTGGTGACT GCACCCACTC CCCTGGCAGC CTGAAAATCA GCTTGCTCAA TGGAGTCACT
CCTGTTCAAA GCTTTTTAGA CAACCTCACA GGGATATTGA CTAAAGTCCT TCCTGAGCTG
ATCCAGGGCA AGGTATGTCC TCTGGTCAAT GGGATTCTCA GCGGTTTGGA TGTCACCCTG
GTGCACAACA TTGCTGAATT ACTGATCCAT GGACTACAGT TTGTCATCAA AGTTTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_035256.2 CDS 60..896 Translation 
Target ORF information:
RefSeq Version NM_011126.3 Organism Mus musculus(house mouse) Definition Mus musculus BPI fold containing family A, member 1 (Bpifa1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_011126.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781ATGTTTCTAG TTGGGAGCCT CGTTGTCCTC TGTGGGCTGC TGGCCCACAG CACAGCACAG
CTGGCAGGCT TGCCATTGCC CCTGGGCCAG GGTCCACCCT TGCCACTGAA CCAGGGCCCA
CCGTTGCCAC TGAACCAGGG CCAGCTGTTG CCCCTGGCTC AGGGTCTGCC TTTGGCTGTA
AGCCCAGCAC TGCCTTCAAA TCCCACAGAT CTTCTTGCTG GAAAATTCAC AGATGCTCTC
AGCGGTGGCC TGCTGTCTGG GGGGCTGCTG GGCATTTTGG AAAATATTCC ACTCCTGGAT
GTTATAAAGT CTGGAGGAGG CAATTCTAAT GGCCTTGTTG GGGGCCTGCT GGGAAAACTG
ACGTCATCAG TTCCTCTCCT GAACAACATC CTCGACATAA AAATCACTGA TCCGCAGCTG
CTAGAACTTG GTCTTGTGCA GAGTCCTGAT GGCCATCGTC TCTATGTCAC CATCCCTCTG
GGCTTGACAC TCAACGTAAA TATGCCCGTA GTTGGAAGTC TTTTGCAATT GGCTGTGAAG
CTGAACATTA CTGCAGAAGT CTTAGCCGTG AAAGACAATC AGGGGAGGAT TCATCTGGTT
CTTGGTGACT GCACCCACTC CCCTGGCAGC CTGAAAATCA GCTTGCTCAA TGGAGTCACT
CCTGTTCAAA GCTTTTTAGA CAACCTCACA GGGATATTGA CTAAAGTCCT TCCTGAGCTG
ATCCAGGGCA AGGTATGTCC TCTGGTCAAT GGGATTCTCA GCGGTTTGGA TGTCACCCTG
GTGCACAACA TTGCTGAATT ACTGATCCAT GGACTACAGT TTGTCATCAA AGTTTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Chronic otitis media is initiated by a bulla cavitation defect in the FBXO11 mouse model.
Disease models & mechanisms12(3)(2019 03)
Del-Pozo J,MacIntyre N,Azar A,Glover J,Milne E,Cheeseman M
BPIFA1 regulates lung neutrophil recruitment and interferon signaling during acute inflammation.
American journal of physiology. Lung cellular and molecular physiology316(2)L321-L333(2019 02)
Britto CJ,Niu N,Khanal S,Huleihel L,Herazo-Maya JD,Thompson A,Sauler M,Slade MD,Sharma L,Dela Cruz CS,Kaminski N,Cohn LE
Loss of the homeostatic protein BPIFA1, leads to exacerbation of otitis media severity in the Junbo mouse model.
Scientific reports8(1)3128(2018 02)
Mulay A,Hood DW,Williams D,Russell C,Brown SDM,Bingle L,Cheeseman M,Bingle CD
An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection.
Mucosal immunology11(1)71-81(2018 01)
Akram KM,Moyo NA,Leeming GH,Bingle L,Jasim S,Hussain S,Schorlemmer A,Kipar A,Digard P,Tripp RA,Shohet RV,Bingle CD,Stewart JP
SPLUNC1 knockout enhances LPS-induced lung injury by increasing recruitment of CD11b+Gr-1+ cells to the spleen of mice.
Oncology reports39(1)358-366(2018 Jan)
Zhang H,Li X,Liao S,Wang H,Chen P,Zhu G,Luo Y,Li G,Zhou Y
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