| Gene Symbol | Nsdhl |
| Entrez Gene ID | 18194 |
| Full Name | NAD(P) dependent steroid dehydrogenase-like |
| Synonyms | AI747449,Bpa,H105E3,Str,XAP104 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Nsdhl cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Nsdhl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nsdhl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu07205 Clone ID Related Accession (Same CDS sequence) NM_010941.3 Accession Version NM_010941.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1089bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577203200000 Organism Mus musculus(house mouse) Product sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671908.8 and AK140930.1. On Jun 19, 2003 this sequence version replaced NM_010941.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF100198.1, AK140930.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGGAACAAG CTGTTCATGG TGAATCAAAG CGAGGCCAGG TCACAGGAAC ACATTTGACA
AATGACATTT CCAAAGCTAA GAAGTGCACA GTGATTGGAG GCTCTGGGTT CCTGGGGCAG
CACATGGTGG AGCAGTTGCT GGAGCGAGGC TATACTGTCA ATGTATTTGA TATCCACCAA
GGCTTTGATA ACCCCCGGGT GCAGTTCTTT ATAGGCGACC TGTGCAACCA ACAGGACCTG
TACCCAGCTC TCAAAGGTGT AAGCACAGTT TTCCACTGCG CGTCCCCTCC GCCGTACAGT
AACAACAAGG AGCTCTTTTA TAGAGTGAAT TTCATTGGCA CCAAGACTGT CATTGAAACC
TGCAGAGAGG CCGGAGTTCA GAAACTCATT TTAACCAGCA GTGCCAGTGT TGTCTTTGAG
GGTGTTGACA TAAAAAATGG AACTGAAGAC CTCCCTTACG CCATGAAGCC TATTGACTAT
TACACAGAGA CCAAGATCTT GCAGGAGAGA GCAGTACTGG ATGCCAACGA CCCTAAGAAG
AATTTTTTAA CCGCAGCCAT TCGTCCTCAT GGCATTTTCG GCCCAAGGGA CCCCCAGTTG
GTCCCAATCC TAATTGATGC AGCTAGAAAG GGCAAAATGA AGTTCATGAT TGGAAATGGG
GAAAACCTGG TGGACTTCAC CTTCGTGGAG AATGTGGTTC ATGGACACAT CTTAGCCGCT
GAGCACCTCT CCCAAGATGC AGCTCTAGGT GGAAAGGCAT TTCACATCAC CAACGATGAA
CCAATCCCTT TCTGGACGTT CCTGTCCCGC ATTCTGACAG GCCTCAATTA TGAGGCCCCT
AAGTACCACA TCCCCTACTG GATGGCCTAT TACCTTGCTT TCCTGCTATC TCTACTGGTG
ATGGTGGTCA GCCCTCTCAT CCAAATCCAG CCAACCTTTA CACCAATTCG AGTGGCATTG
GCTGGAACAT TCCACTATTA CAGTTGTGAA AAAGCCAAAA AGCTCTTTGG GTACCGGCCA
CTGGTCACCA TGGATGAAGC TGTGGAAAGG ACTGTGCAGA GTTTCCACCA CCTGCGGAAG
GACAAGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_035071.3 CDS 216..1304 Translation 
Target ORF information:
RefSeq Version NM_010941.3 Organism Mus musculus(house mouse) Definition Mus musculus NAD(P) dependent steroid dehydrogenase-like (Nsdhl), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_010941.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGGAACAAG CTGTTCATGG TGAATCAAAG CGAGGCCAGG TCACAGGAAC ACATTTGACA
AATGACATTT CCAAAGCTAA GAAGTGCACA GTGATTGGAG GCTCTGGGTT CCTGGGGCAG
CACATGGTGG AGCAGTTGCT GGAGCGAGGC TATACTGTCA ATGTATTTGA TATCCACCAA
GGCTTTGATA ACCCCCGGGT GCAGTTCTTT ATAGGCGACC TGTGCAACCA ACAGGACCTG
TACCCAGCTC TCAAAGGTGT AAGCACAGTT TTCCACTGCG CGTCCCCTCC GCCGTACAGT
AACAACAAGG AGCTCTTTTA TAGAGTGAAT TTCATTGGCA CCAAGACTGT CATTGAAACC
TGCAGAGAGG CCGGAGTTCA GAAACTCATT TTAACCAGCA GTGCCAGTGT TGTCTTTGAG
GGTGTTGACA TAAAAAATGG AACTGAAGAC CTCCCTTACG CCATGAAGCC TATTGACTAT
TACACAGAGA CCAAGATCTT GCAGGAGAGA GCAGTACTGG ATGCCAACGA CCCTAAGAAG
AATTTTTTAA CCGCAGCCAT TCGTCCTCAT GGCATTTTCG GCCCAAGGGA CCCCCAGTTG
GTCCCAATCC TAATTGATGC AGCTAGAAAG GGCAAAATGA AGTTCATGAT TGGAAATGGG
GAAAACCTGG TGGACTTCAC CTTCGTGGAG AATGTGGTTC ATGGACACAT CTTAGCCGCT
GAGCACCTCT CCCAAGATGC AGCTCTAGGT GGAAAGGCAT TTCACATCAC CAACGATGAA
CCAATCCCTT TCTGGACGTT CCTGTCCCGC ATTCTGACAG GCCTCAATTA TGAGGCCCCT
AAGTACCACA TCCCCTACTG GATGGCCTAT TACCTTGCTT TCCTGCTATC TCTACTGGTG
ATGGTGGTCA GCCCTCTCAT CCAAATCCAG CCAACCTTTA CACCAATTCG AGTGGCATTG
GCTGGAACAT TCCACTATTA CAGTTGTGAA AAAGCCAAAA AGCTCTTTGG GTACCGGCCA
CTGGTCACCA TGGATGAAGC TGTGGAAAGG ACTGTGCAGA GTTTCCACCA CCTGCGGAAG
GACAAGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
RNA-Seq analysis reveals a negative role of MSMO1 with a synergized NSDHL expression during adipogenesis of 3T3-L1.
Bioscience, biotechnology, and biochemistry83(4)641-652(2019 Apr)
Xin Y,Li C,Guo Y,Xiao R,Zhang H,Zhou G
A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.
Journal of lipid research56(8)1551-9(2015 Aug)
Şişecioğlu M,Budak H,Geffers L,Çankaya M,Çiftci M,Thaller C,Eichele G,Küfrevioğlu Öİ,Özdemir H
Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development.
Human molecular genetics24(10)2808-25(2015 May)
Cunningham D,DeBarber AE,Bir N,Binkley L,Merkens LS,Steiner RD,Herman GE
Identification of a novel polymorphism in X-linked sterol-4-alpha-carboxylate 3-dehydrogenase (Nsdhl) associated with reduced high-density lipoprotein cholesterol levels in I/LnJ mice.
G3 (Bethesda, Md.)3(10)1819-25(2013 Oct)
Bautz DJ,Broman KW,Threadgill DW
Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Cancer discovery3(1)96-111(2013 Jan)
Sukhanova A,Gorin A,Serebriiskii IG,Gabitova L,Zheng H,Restifo D,Egleston BL,Cunningham D,Bagnyukova T,Liu H,Nikonova A,Adams GP,Zhou Y,Yang DH,Mehra R,Burtness B,Cai KQ,Klein-Szanto A,Kratz LE,Kelley RI,Weiner LM,Herman GE,Golemis EA,Astsaturov I
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