| Gene Symbol | Ghrhr |
| Entrez Gene ID | 14602 |
| Full Name | growth hormone releasing hormone receptor |
| Synonyms | Ghrfr,lit,little |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Ghrhr cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Ghrhr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ghrhr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu10507 Clone ID Related Accession (Same CDS sequence) NM_001003685.3 Accession Version NM_001003685.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1272bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577721600000 Organism Mus musculus(house mouse) Product growth hormone-releasing hormone receptor precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB618094.1, AK030504.1, AC083946.5 and BB027246.1. On May 21, 2010 this sequence version replaced NM_001003685.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK030504.1, L07379.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261ATGGATGGCC TGATGTGGGC TACCCGTATC CTCTGCTTGC TGAGCCTGTG CGGAGTTACA
CTGGGTCACC TCCACCTAGA ATGTGACTTC ATCACTCAGC TGAGAGACGA TGAGCTTGCA
TGTCTTCAGG CGGCAGAGGG GACCAACAAC ACCTCCCTGG GATGCCCTGG GACCTGGGAT
GGGCTGCTGT GCTGGCCCCC GACAGGCTCT GGCCAGTGGG TCTCTCTCCC CTGCCCTGAA
TTCTTCTCTC ACTTCGGCTC AGACACAGGG TTTGTGAAGA GGGACTGCAC CATCACTGGC
TGGTCTAATC CCTTCCCACC ATACCCTGTG GCTTGCCCTG TGCCCTTGGA ACTGTTAACC
AAGGAGAAAT CGTACTTCTC CACGGTGAAG ATCATCTACA CCACGGGCCA CAGCATCTCC
ATTGTAGCCC TCTGCGTGGC TATTGCCATC CTGGTTGCCC TCAGGAGGCT CCACTGCCCC
AGGAACTACA TCCACACGCA GCTGTTTGCC ACCTTCATCC TCAAGGCCAG TGCTGTGTTC
TTGAAGGATG CCGCCATCTT CCAGGGGGAT AGCACGGACC ACTGCAGCAT GTCCACTGTC
CTGTGCAAGG TCTCTGTGGC CATCTCACAT TTGGCCACCA TGACCAACTT CAGCTGGCTG
TTGGCAGAAG CTGTCTACCT GAGCTGCCTG TTGGCCTCCA CATCCCCCAG GTCCAAACCA
GCTTTTTGGT GGCTGGTCCT GGCTGGCTGG GGGCTCCCCG TGCTATGCAC TGGTACGTGG
GTGGGCTGCA AACTGGCTTT TGAGGACACT GAGTGCTGGG ACTTAGACAA CAGCTCCCCC
TGCTGGTGGA TCATCAAAGG ACCCATAGTC CTCTCTGTTG GGGTGAACTT TGGGCTGTTT
CTCAATATAA TTTGTATCCT GCTGAGGAAG CTGGAGCCTG CACAAGGCGG CCTACACACA
CGGGCTCAGT ACTGGCGGCT TTCCAAGTCA ACACTTCTCC TTATACCGCT GTTTGGAATT
CATTACATCA TCTTCAACTT CCTGCCTGAC AGTGCTGGCC TTGACATCCG TGTACCCCTG
GAGCTGGGGT TGGGGTCCTT TCAGGGCTTC ATTGTTGCTG TCCTCTACTG CTTCCTCAAT
CAAGAGGTGA GGACAGAGAT TTCACGCAAA TGGTATGGCC ACGACCCTGA ACTTCTGCCA
GCTCGACGGA CCTGCACTGA GTGGACCACA CCTCCCCGAT CGAGATTGAA GGTGCTGACC
TCTGAGTGCT AGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001003685.2 CDS 91..1362 Translation 
Target ORF information:
RefSeq Version NM_001003685.3 Organism Mus musculus(house mouse) Definition Mus musculus growth hormone releasing hormone receptor (Ghrhr), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001003685.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261ATGGATGGCC TGATGTGGGC TACCCGTATC CTCTGCTTGC TGAGCCTGTG CGGAGTTACA
CTGGGTCACC TCCACCTAGA ATGTGACTTC ATCACTCAGC TGAGAGACGA TGAGCTTGCA
TGTCTTCAGG CGGCAGAGGG GACCAACAAC ACCTCCCTGG GATGCCCTGG GACCTGGGAT
GGGCTGCTGT GCTGGCCCCC GACAGGCTCT GGCCAGTGGG TCTCTCTCCC CTGCCCTGAA
TTCTTCTCTC ACTTCGGCTC AGACACAGGG TTTGTGAAGA GGGACTGCAC CATCACTGGC
TGGTCTAATC CCTTCCCACC ATACCCTGTG GCTTGCCCTG TGCCCTTGGA ACTGTTAACC
AAGGAGAAAT CGTACTTCTC CACGGTGAAG ATCATCTACA CCACGGGCCA CAGCATCTCC
ATTGTAGCCC TCTGCGTGGC TATTGCCATC CTGGTTGCCC TCAGGAGGCT CCACTGCCCC
AGGAACTACA TCCACACGCA GCTGTTTGCC ACCTTCATCC TCAAGGCCAG TGCTGTGTTC
TTGAAGGATG CCGCCATCTT CCAGGGGGAT AGCACGGACC ACTGCAGCAT GTCCACTGTC
CTGTGCAAGG TCTCTGTGGC CATCTCACAT TTGGCCACCA TGACCAACTT CAGCTGGCTG
TTGGCAGAAG CTGTCTACCT GAGCTGCCTG TTGGCCTCCA CATCCCCCAG GTCCAAACCA
GCTTTTTGGT GGCTGGTCCT GGCTGGCTGG GGGCTCCCCG TGCTATGCAC TGGTACGTGG
GTGGGCTGCA AACTGGCTTT TGAGGACACT GAGTGCTGGG ACTTAGACAA CAGCTCCCCC
TGCTGGTGGA TCATCAAAGG ACCCATAGTC CTCTCTGTTG GGGTGAACTT TGGGCTGTTT
CTCAATATAA TTTGTATCCT GCTGAGGAAG CTGGAGCCTG CACAAGGCGG CCTACACACA
CGGGCTCAGT ACTGGCGGCT TTCCAAGTCA ACACTTCTCC TTATACCGCT GTTTGGAATT
CATTACATCA TCTTCAACTT CCTGCCTGAC AGTGCTGGCC TTGACATCCG TGTACCCCTG
GAGCTGGGGT TGGGGTCCTT TCAGGGCTTC ATTGTTGCTG TCCTCTACTG CTTCCTCAAT
CAAGAGGTGA GGACAGAGAT TTCACGCAAA TGGTATGGCC ACGACCCTGA ACTTCTGCCA
GCTCGACGGA CCTGCACTGA GTGGACCACA CCTCCCCGAT CGAGATTGAA GGTGCTGACC
TCTGAGTGCT AGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models.
Endocrinology160(11)2673-2691(2019 11)
Ariyasu D,Kubo E,Higa D,Shibata S,Takaoka Y,Sugimoto M,Imaizumi K,Hasegawa T,Araki K
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
PloS one12(7)e0180682(2017)
Sundberg JP,Dadras SS,Silva KA,Kennedy VE,Garland G,Murray SA,Sundberg BA,Schofield PN,Pratt CH
Foxo1 Is Required for Normal Somatotrope Differentiation.
Endocrinology157(11)4351-4363(2016 Nov)
Kapali J,Kabat BE,Schmidt KL,Stallings CE,Tippy M,Jung DO,Edwards BS,Nantie LB,Raeztman LT,Navratil AM,Ellsworth BS
High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA
Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross.
PLoS genetics12(2)e1005805(2016 Feb)
Tyler AL,Donahue LR,Churchill GA,Carter GW
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