| Gene Symbol | Adm |
| Entrez Gene ID | 11535 |
| Full Name | adrenomedullin |
| Synonyms | AM |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Adm cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Adm gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adm cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu15683 Clone ID Related Accession (Same CDS sequence) NM_009627.1 , NM_009627.2 Accession Version NM_009627.1 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 555bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1514217600000 Organism Mus musculus(house mouse) Product ADM precursor Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U77630.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U77630.1, AK144181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541ATGAAGCTGG TTTCCATCAC CCTGATGTTA TTGGGTTCAC TCGCTTTCCT AGGCGCGGAC
ACTGCAGGGC CAGATACTCC TTCGCAGTTC CGAAAGAAGT GGAATAAGTG GGCGCTAAGT
CGTGGGAAGA GGGAACTACA AGCATCCAGC AGCTACCCTA CGGGACTCGC TGATGAGACG
ACAGTTCCTA CCCAGACTCT TGATCCATTC CTGGACGAGC AGAACACAAC TGGCCCCCTA
CAAGCCAGCA ATCAGAGCGA AGCCCACATT CGTGTCAAAC GCTACCGCCA GAGCATGAAC
CAGGGTTCCC GCAGCAATGG ATGCCGCTTC GGGACCTGCA CATTTCAGAA ATTGGCCCAC
CAGATCTACC AGCTAACAGA CAAAGACAAG GACGGCATGG CTCCCAGAAA CAAGATCAGC
CCTCAAGGCT ATGGCCGCCG GCGCCGGCGT TCCCTGCTGG AGGTCCTCCG GTCCCGGACT
GTGGAGTCCT CCCAGGAGCA GACACACACA GCCCCAGGCC CCTGGGCGCA CATCTCCAGA
CTCTTTAGGA TATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_033757.1 CDS 176..730 Translation 
Target ORF information:
RefSeq Version NM_009627.1 Organism Mus musculus(house mouse) Definition Mus musculus adrenomedullin (Adm), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_009627.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541ATGAAGCTGG TTTCCATCAC CCTGATGTTA TTGGGTTCAC TCGCTTTCCT AGGCGCGGAC
ACTGCAGGGC CAGATACTCC TTCGCAGTTC CGAAAGAAGT GGAATAAGTG GGCGCTAAGT
CGTGGGAAGA GGGAACTACA AGCATCCAGC AGCTACCCTA CGGGACTCGC TGATGAGACG
ACAGTTCCTA CCCAGACTCT TGATCCATTC CTGGACGAGC AGAACACAAC TGGCCCCCTA
CAAGCCAGCA ATCAGAGCGA AGCCCACATT CGTGTCAAAC GCTACCGCCA GAGCATGAAC
CAGGGTTCCC GCAGCAATGG ATGCCGCTTC GGGACCTGCA CATTTCAGAA ATTGGCCCAC
CAGATCTACC AGCTAACAGA CAAAGACAAG GACGGCATGG CTCCCAGAAA CAAGATCAGC
CCTCAAGGCT ATGGCCGCCG GCGCCGGCGT TCCCTGCTGG AGGTCCTCCG GTCCCGGACT
GTGGAGTCCT CCCAGGAGCA GACACACACA GCCCCAGGCC CCTGGGCGCA CATCTCCAGA
CTCTTTAGGA TATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OMu15683 Clone ID Related Accession (Same CDS sequence) NM_009627.1 , NM_009627.2 Accession Version NM_009627.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 555bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1572105600000 Organism Mus musculus(house mouse) Product ADM precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK144181.1 and AC154911.4. On Mar 28, 2018 this sequence version replaced NM_009627.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052665.1, AK144181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541ATGAAGCTGG TTTCCATCAC CCTGATGTTA TTGGGTTCAC TCGCTTTCCT AGGCGCGGAC
ACTGCAGGGC CAGATACTCC TTCGCAGTTC CGAAAGAAGT GGAATAAGTG GGCGCTAAGT
CGTGGGAAGA GGGAACTACA AGCATCCAGC AGCTACCCTA CGGGACTCGC TGATGAGACG
ACAGTTCCTA CCCAGACTCT TGATCCATTC CTGGACGAGC AGAACACAAC TGGCCCCCTA
CAAGCCAGCA ATCAGAGCGA AGCCCACATT CGTGTCAAAC GCTACCGCCA GAGCATGAAC
CAGGGTTCCC GCAGCAATGG ATGCCGCTTC GGGACCTGCA CATTTCAGAA ATTGGCCCAC
CAGATCTACC AGCTAACAGA CAAAGACAAG GACGGCATGG CTCCCAGAAA CAAGATCAGC
CCTCAAGGCT ATGGCCGCCG GCGCCGGCGT TCCCTGCTGG AGGTCCTCCG GTCCCGGACT
GTGGAGTCCT CCCAGGAGCA GACACACACA GCCCCAGGCC CCTGGGCGCA CATCTCCAGA
CTCTTTAGGA TATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_033757.1 CDS 188..742 Translation
Target ORF information:
RefSeq Version NM_009627.2 Organism Mus musculus(house mouse) Definition Mus musculus adrenomedullin (Adm), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_009627.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541ATGAAGCTGG TTTCCATCAC CCTGATGTTA TTGGGTTCAC TCGCTTTCCT AGGCGCGGAC
ACTGCAGGGC CAGATACTCC TTCGCAGTTC CGAAAGAAGT GGAATAAGTG GGCGCTAAGT
CGTGGGAAGA GGGAACTACA AGCATCCAGC AGCTACCCTA CGGGACTCGC TGATGAGACG
ACAGTTCCTA CCCAGACTCT TGATCCATTC CTGGACGAGC AGAACACAAC TGGCCCCCTA
CAAGCCAGCA ATCAGAGCGA AGCCCACATT CGTGTCAAAC GCTACCGCCA GAGCATGAAC
CAGGGTTCCC GCAGCAATGG ATGCCGCTTC GGGACCTGCA CATTTCAGAA ATTGGCCCAC
CAGATCTACC AGCTAACAGA CAAAGACAAG GACGGCATGG CTCCCAGAAA CAAGATCAGC
CCTCAAGGCT ATGGCCGCCG GCGCCGGCGT TCCCTGCTGG AGGTCCTCCG GTCCCGGACT
GTGGAGTCCT CCCAGGAGCA GACACACACA GCCCCAGGCC CCTGGGCGCA CATCTCCAGA
CTCTTTAGGA TATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.
The Journal of clinical investigation129(7)2775-2791(2019 06)
Iring A,Jin YJ,Albarrán-Juárez J,Siragusa M,Wang S,Dancs PT,Nakayama A,Tonack S,Chen M,Künne C,Sokol AM,Günther S,Martínez A,Fleming I,Wettschureck N,Graumann J,Weinstein LS,Offermanns S
USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Development (Cambridge, England)146(4)(2019 02)
Koutelou E,Wang L,Schibler AC,Chao HP,Kuang X,Lin K,Lu Y,Shen J,Jeter CR,Salinger A,Wilson M,Chen YC,Atanassov BS,Tang DG,Dent SYR
Genetic loss of proadrenomedullin N-terminal 20 peptide (PAMP) in mice is compatible with survival.
Peptides11296-100(2019 02)
Matson BC,Li M,Trincot CE,Blakeney ES,Pierce SL,Caron KM
Development of a Novel Model of Central Retinal Vascular Occlusion and the Therapeutic Potential of the Adrenomedullin-Receptor Activity-Modifying Protein 2 System.
The American journal of pathology189(2)449-466(2019 02)
Hirabayashi K,Tanaka M,Imai A,Toriyama Y,Iesato Y,Sakurai T,Kamiyoshi A,Ichikawa-Shindo Y,Kawate H,Tanaka M,Dai K,Cui N,Wei Y,Nakamura K,Iida S,Matsui S,Yamauchi A,Murata T,Shindo T
Adrenomedullin Induces Cardiac Lymphangiogenesis After Myocardial Infarction and Regulates Cardiac Edema Via Connexin 43.
Circulation research124(1)101-113(2019 01)
Trincot CE,Xu W,Zhang H,Kulikauskas MR,Caranasos TG,Jensen BC,Sabine A,Petrova TV,Caron KM
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