Rcc2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rcc2
Entrez Gene ID	108911
Full Name	regulator of chromosome condensation 2
Synonyms	2610510H01Rik,2610529N02Rik,AA536646,AA675016,Td60,mKIAA1470
General protein information	Preferred Names regulator of chromosome condensation 2 Names protein RCC2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 D3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006538471.3	XP_006538534.1	protein RCC2 isoform X1
NM_173867.5	NP_776292.1	protein RCC2

Pathways from BioSystems

Homologies

Homo sapiens (human)	RCC2	NP_001129676.1
Bos taurus (cattle)	RCC2	NP_001095381.2
Mus musculus (house mouse)	Rcc2	NP_776292.1
Rattus norvegicus (Norway rat)	Rcc2	XP_006239362.1
Drosophila melanogaster (fruit fly)	CG9135	NP_608985.1
Oryza sativa (rice)	Os04g0662800	NP_001054159.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002151	XP_308044.2
Danio rerio (zebrafish)	rcc2	NP_998341.1
Gallus gallus (chicken)	RCC2	XP_004947346.1
Pan troglodytes (chimpanzee)	RCC2	XP_513117.2
Canis lupus familiaris (dog)	RCC2	XP_005618067.1
Arabidopsis thaliana (thale cress)	AT1G19880	NP_173417.2
Xenopus tropicalis (tropical clawed frog)	LOC100494942	XP_002942173.2

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

The epidermal growth factor receptor decreases Stathmin 1 and triggers catagen entry in the mouse.
Bichsel KJ, Hammiller B, Trempus CS, Li Y, Hansen LA
Experimental dermatology25(4)275-81(2016 Apr)

Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure.
Williamson RC, Cowell CA, Hammond CL, Bergen DJ, Roper JA, Feng Y, Rendall TC, Race PR, Bass MD
Journal of cell science127(Pt 19)4292-307(2014 Oct)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.
Humphries JD, Byron A, Bass MD, Craig SE, Pinney JW, Knight D, Humphries MJ
Science signaling2(87)ra51(2009 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rcc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rcc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15834	NM_173867.5 Latest version!	Mus musculus regulator of chromosome condensation 2 (Rcc2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu15834	XM_006538471.3 Latest version!	Mus musculus regulator of chromosome condensation 2 (Rcc2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rcc2 ( NM_173867.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_776292.1 Mus musculus regulator of chromosome condensation 2 (Rcc2), mRNA.

Price & Availability↑

CloneID	OMu15834
Clone ID Related Accession (Same CDS sequence)	XM_006538471.3 , NM_173867.5
Accession Version	NM_173867.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	protein RCC2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA751510.1, AK076040.1, AL954710.27 and BC060624.1. On May 1, 2010 this sequence version replaced NM_173867.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC060624.1, AK076040.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCCAGGA AGAAGGGGGC GGCCTGGGAG GAGCCGAGTT CGGGCAACGG CACGGCGCGC 
GCGGGGCCCC GGCGACGCGG CGGCCCCGCG GGCAGGAAGC GCGAGCGGCC CGAGCGCTGC 
AGCAGCAGCA GCGGCGGCGG CAGCAGCGGC GACGAGGACG GCCCGGAGCT GGACGGGGCC 
CCCGGCGGCG GCAAGCGCAC AGCCAGGCCG GCGACGGCGG GCAAGGCGGC CGGCGCGGCC 
GCGATCATCA CGGAGCCCGA GCACACGAAG GAGCGCGTCA AACTTGAAGG GTCTAAGTGC 
AAAGGGCAGC TTTTGATTTT TGGGGCAACC AACTGGGACT TGATTGGACG GAAGGAAGTG 
CCTAAACAGC AAGCTGCGTA CCGCAACCTT GGTCAGAATT TGTGGGGGCC CCATAGGTAT 
GGGTGCCTGT CAGGAGTCCG GGTGCGAACC GTGGTTTCAG GCTCATGTGC TGCCCACAGC 
CTCCTCATCA CCACAGAAGG GAAGCTGTGG AGCTGGGGTC GGAATGAGAA GGGGCAGCTG 
GGCCATGGTG ATACCAAGAG GGTGGAAGCC CCCAGACTCA TCGAGGCCCT CAGCCATGAG 
GCAATCGTGC TGGCAGCCTG TGGGCGCAAC CACACCCTGG CCTTGACAGA TACTGGATCA 
GTGTTTGCCT TCGGAGAGAA TAAAATGGGG CAGCTGGGTC TCGGGAACCA GACAGATGCC 
GTCCCAAGTC CTGCTCAGAT AATGTACAAC GGGCAGCCAA TCACCAAGAT GGCCTGCGGG 
GCCGAGTTCA GCATGCTGAT GGACTGTAAA GGAAACCTCT ACTCCTTTGG GTGCCCTGAG 
TATGGCCAGC TGGGGCACAA CTCAGATGGC AAGTTCATCG CCCGGGCGCA GAGGATAGAA 
TATGATTGTG AGCTGGTGCC CCGCAGAGTG GCCATCTTCA TCGAGAAGAC CAAGGACGGG 
CAGATCTTAC CTGTCCCCAA CGTGGTGGTT CGAGATGTAG CCTGTGGCGC TAACCACACA 
CTGGTCCTGG ACTCTCAGAA GCGAGTGTTC TCCTGGGGCT TTGGTGGCTA TGGCCGGCTG 
GGCCATGCCG AGCAGAAGGA TGAGATGGTG CCTCGCCTGG TGAAGCTGTT CGACTTCCCG 
GGGCGTGGTG CAACCCAGAT CTATGCCGGC TACACCTGCT CCTTCGCTGT CAGTGAAGTG 
GGTGGCCTGT TTTTCTGGGG GGCCACCAAT ACCTCCCGAG AGTCTACCAT GTACCCGAAG 
GCAGTGCAGG ACCTCTGCGG CTGGCGGATC CGGAGCCTTG CCTGCGGGAA GAGCAGCATC 
ATCGTAGCTG CGGACGAGAG TACTATCAGT TGGGGTCCAT CGCCAACCTT CGGGGAATTG 
GGGTATGGGG ACCACAAGCC CAAGTCTTCT ACTGCGGCCC AGGAGGTGAA GACTCTGGAT 
GGCATCTTCT CCGAACAGGT GGCCATGGGC TATTCACACT CCTTGGTGAT AGCGCGAGAC 
GAGAGCGAGG CTGAGAAGGA GAAGCTGCAG AGGCTACCTG AGTACACCCC GCGCACCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776292.1
CDS	189..1751
Translation	MPRKKGAAWEEPSSGNGTARAGPRRRGGPAGRKRERPERCSSSSGGGSSGDEDGPELDGAPGGGKRTARPATAGKAAGAAAIITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLSGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEALSHEAIVLAACGRNHTLALTDTGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMLMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESEAEKEKLQRLPEYTPRTL

Target ORF information:

RefSeq Version	NM_173867.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus regulator of chromosome condensation 2 (Rcc2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173867.5

ORF Insert Sequence:

ATGCCCAGGA AGAAGGGGGC GGCCTGGGAG GAGCCGAGTT CGGGCAACGG CACGGCGCGC 
GCGGGGCCCC GGCGACGCGG CGGCCCCGCG GGCAGGAAGC GCGAGCGGCC CGAGCGCTGC 
AGCAGCAGCA GCGGCGGCGG CAGCAGCGGC GACGAGGACG GCCCGGAGCT GGACGGGGCC 
CCCGGCGGCG GCAAGCGCAC AGCCAGGCCG GCGACGGCGG GCAAGGCGGC CGGCGCGGCC 
GCGATCATCA CGGAGCCCGA GCACACGAAG GAGCGCGTCA AACTTGAAGG GTCTAAGTGC 
AAAGGGCAGC TTTTGATTTT TGGGGCAACC AACTGGGACT TGATTGGACG GAAGGAAGTG 
CCTAAACAGC AAGCTGCGTA CCGCAACCTT GGTCAGAATT TGTGGGGGCC CCATAGGTAT 
GGGTGCCTGT CAGGAGTCCG GGTGCGAACC GTGGTTTCAG GCTCATGTGC TGCCCACAGC 
CTCCTCATCA CCACAGAAGG GAAGCTGTGG AGCTGGGGTC GGAATGAGAA GGGGCAGCTG 
GGCCATGGTG ATACCAAGAG GGTGGAAGCC CCCAGACTCA TCGAGGCCCT CAGCCATGAG 
GCAATCGTGC TGGCAGCCTG TGGGCGCAAC CACACCCTGG CCTTGACAGA TACTGGATCA 
GTGTTTGCCT TCGGAGAGAA TAAAATGGGG CAGCTGGGTC TCGGGAACCA GACAGATGCC 
GTCCCAAGTC CTGCTCAGAT AATGTACAAC GGGCAGCCAA TCACCAAGAT GGCCTGCGGG 
GCCGAGTTCA GCATGCTGAT GGACTGTAAA GGAAACCTCT ACTCCTTTGG GTGCCCTGAG 
TATGGCCAGC TGGGGCACAA CTCAGATGGC AAGTTCATCG CCCGGGCGCA GAGGATAGAA 
TATGATTGTG AGCTGGTGCC CCGCAGAGTG GCCATCTTCA TCGAGAAGAC CAAGGACGGG 
CAGATCTTAC CTGTCCCCAA CGTGGTGGTT CGAGATGTAG CCTGTGGCGC TAACCACACA 
CTGGTCCTGG ACTCTCAGAA GCGAGTGTTC TCCTGGGGCT TTGGTGGCTA TGGCCGGCTG 
GGCCATGCCG AGCAGAAGGA TGAGATGGTG CCTCGCCTGG TGAAGCTGTT CGACTTCCCG 
GGGCGTGGTG CAACCCAGAT CTATGCCGGC TACACCTGCT CCTTCGCTGT CAGTGAAGTG 
GGTGGCCTGT TTTTCTGGGG GGCCACCAAT ACCTCCCGAG AGTCTACCAT GTACCCGAAG 
GCAGTGCAGG ACCTCTGCGG CTGGCGGATC CGGAGCCTTG CCTGCGGGAA GAGCAGCATC 
ATCGTAGCTG CGGACGAGAG TACTATCAGT TGGGGTCCAT CGCCAACCTT CGGGGAATTG 
GGGTATGGGG ACCACAAGCC CAAGTCTTCT ACTGCGGCCC AGGAGGTGAA GACTCTGGAT 
GGCATCTTCT CCGAACAGGT GGCCATGGGC TATTCACACT CCTTGGTGAT AGCGCGAGAC 
GAGAGCGAGG CTGAGAAGGA GAAGCTGCAG AGGCTACCTG AGTACACCCC GCGCACCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rcc2 ( XM_006538471.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538534.1 Mus musculus regulator of chromosome condensation 2 (Rcc2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu15834
Clone ID Related Accession (Same CDS sequence)	XM_006538471.3 , NM_173867.5
Accession Version	XM_006538471.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	protein RCC2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538471.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCAGGA AGAAGGGGGC GGCCTGGGAG GAGCCGAGTT CGGGCAACGG CACGGCGCGC 
GCGGGGCCCC GGCGACGCGG CGGCCCCGCG GGCAGGAAGC GCGAGCGGCC CGAGCGCTGC 
AGCAGCAGCA GCGGCGGCGG CAGCAGCGGC GACGAGGACG GCCCGGAGCT GGACGGGGCC 
CCCGGCGGCG GCAAGCGCAC AGCCAGGCCG GCGACGGCGG GCAAGGCGGC CGGCGCGGCC 
GCGATCATCA CGGAGCCCGA GCACACGAAG GAGCGCGTCA AACTTGAAGG GTCTAAGTGC 
AAAGGGCAGC TTTTGATTTT TGGGGCAACC AACTGGGACT TGATTGGACG GAAGGAAGTG 
CCTAAACAGC AAGCTGCGTA CCGCAACCTT GGTCAGAATT TGTGGGGGCC CCATAGGTAT 
GGGTGCCTGT CAGGAGTCCG GGTGCGAACC GTGGTTTCAG GCTCATGTGC TGCCCACAGC 
CTCCTCATCA CCACAGAAGG GAAGCTGTGG AGCTGGGGTC GGAATGAGAA GGGGCAGCTG 
GGCCATGGTG ATACCAAGAG GGTGGAAGCC CCCAGACTCA TCGAGGCCCT CAGCCATGAG 
GCAATCGTGC TGGCAGCCTG TGGGCGCAAC CACACCCTGG CCTTGACAGA TACTGGATCA 
GTGTTTGCCT TCGGAGAGAA TAAAATGGGG CAGCTGGGTC TCGGGAACCA GACAGATGCC 
GTCCCAAGTC CTGCTCAGAT AATGTACAAC GGGCAGCCAA TCACCAAGAT GGCCTGCGGG 
GCCGAGTTCA GCATGCTGAT GGACTGTAAA GGAAACCTCT ACTCCTTTGG GTGCCCTGAG 
TATGGCCAGC TGGGGCACAA CTCAGATGGC AAGTTCATCG CCCGGGCGCA GAGGATAGAA 
TATGATTGTG AGCTGGTGCC CCGCAGAGTG GCCATCTTCA TCGAGAAGAC CAAGGACGGG 
CAGATCTTAC CTGTCCCCAA CGTGGTGGTT CGAGATGTAG CCTGTGGCGC TAACCACACA 
CTGGTCCTGG ACTCTCAGAA GCGAGTGTTC TCCTGGGGCT TTGGTGGCTA TGGCCGGCTG 
GGCCATGCCG AGCAGAAGGA TGAGATGGTG CCTCGCCTGG TGAAGCTGTT CGACTTCCCG 
GGGCGTGGTG CAACCCAGAT CTATGCCGGC TACACCTGCT CCTTCGCTGT CAGTGAAGTG 
GGTGGCCTGT TTTTCTGGGG GGCCACCAAT ACCTCCCGAG AGTCTACCAT GTACCCGAAG 
GCAGTGCAGG ACCTCTGCGG CTGGCGGATC CGGAGCCTTG CCTGCGGGAA GAGCAGCATC 
ATCGTAGCTG CGGACGAGAG TACTATCAGT TGGGGTCCAT CGCCAACCTT CGGGGAATTG 
GGGTATGGGG ACCACAAGCC CAAGTCTTCT ACTGCGGCCC AGGAGGTGAA GACTCTGGAT 
GGCATCTTCT CCGAACAGGT GGCCATGGGC TATTCACACT CCTTGGTGAT AGCGCGAGAC 
GAGAGCGAGG CTGAGAAGGA GAAGCTGCAG AGGCTACCTG AGTACACCCC GCGCACCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538534.1
CDS	107..1669
Translation	MPRKKGAAWEEPSSGNGTARAGPRRRGGPAGRKRERPERCSSSSGGGSSGDEDGPELDGAPGGGKRTARPATAGKAAGAAAIITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLSGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEALSHEAIVLAACGRNHTLALTDTGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMLMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESEAEKEKLQRLPEYTPRTL

Target ORF information:

RefSeq Version	XM_006538471.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus regulator of chromosome condensation 2 (Rcc2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538471.3

ORF Insert Sequence:

ATGCCCAGGA AGAAGGGGGC GGCCTGGGAG GAGCCGAGTT CGGGCAACGG CACGGCGCGC 
GCGGGGCCCC GGCGACGCGG CGGCCCCGCG GGCAGGAAGC GCGAGCGGCC CGAGCGCTGC 
AGCAGCAGCA GCGGCGGCGG CAGCAGCGGC GACGAGGACG GCCCGGAGCT GGACGGGGCC 
CCCGGCGGCG GCAAGCGCAC AGCCAGGCCG GCGACGGCGG GCAAGGCGGC CGGCGCGGCC 
GCGATCATCA CGGAGCCCGA GCACACGAAG GAGCGCGTCA AACTTGAAGG GTCTAAGTGC 
AAAGGGCAGC TTTTGATTTT TGGGGCAACC AACTGGGACT TGATTGGACG GAAGGAAGTG 
CCTAAACAGC AAGCTGCGTA CCGCAACCTT GGTCAGAATT TGTGGGGGCC CCATAGGTAT 
GGGTGCCTGT CAGGAGTCCG GGTGCGAACC GTGGTTTCAG GCTCATGTGC TGCCCACAGC 
CTCCTCATCA CCACAGAAGG GAAGCTGTGG AGCTGGGGTC GGAATGAGAA GGGGCAGCTG 
GGCCATGGTG ATACCAAGAG GGTGGAAGCC CCCAGACTCA TCGAGGCCCT CAGCCATGAG 
GCAATCGTGC TGGCAGCCTG TGGGCGCAAC CACACCCTGG CCTTGACAGA TACTGGATCA 
GTGTTTGCCT TCGGAGAGAA TAAAATGGGG CAGCTGGGTC TCGGGAACCA GACAGATGCC 
GTCCCAAGTC CTGCTCAGAT AATGTACAAC GGGCAGCCAA TCACCAAGAT GGCCTGCGGG 
GCCGAGTTCA GCATGCTGAT GGACTGTAAA GGAAACCTCT ACTCCTTTGG GTGCCCTGAG 
TATGGCCAGC TGGGGCACAA CTCAGATGGC AAGTTCATCG CCCGGGCGCA GAGGATAGAA 
TATGATTGTG AGCTGGTGCC CCGCAGAGTG GCCATCTTCA TCGAGAAGAC CAAGGACGGG 
CAGATCTTAC CTGTCCCCAA CGTGGTGGTT CGAGATGTAG CCTGTGGCGC TAACCACACA 
CTGGTCCTGG ACTCTCAGAA GCGAGTGTTC TCCTGGGGCT TTGGTGGCTA TGGCCGGCTG 
GGCCATGCCG AGCAGAAGGA TGAGATGGTG CCTCGCCTGG TGAAGCTGTT CGACTTCCCG 
GGGCGTGGTG CAACCCAGAT CTATGCCGGC TACACCTGCT CCTTCGCTGT CAGTGAAGTG 
GGTGGCCTGT TTTTCTGGGG GGCCACCAAT ACCTCCCGAG AGTCTACCAT GTACCCGAAG 
GCAGTGCAGG ACCTCTGCGG CTGGCGGATC CGGAGCCTTG CCTGCGGGAA GAGCAGCATC 
ATCGTAGCTG CGGACGAGAG TACTATCAGT TGGGGTCCAT CGCCAACCTT CGGGGAATTG 
GGGTATGGGG ACCACAAGCC CAAGTCTTCT ACTGCGGCCC AGGAGGTGAA GACTCTGGAT 
GGCATCTTCT CCGAACAGGT GGCCATGGGC TATTCACACT CCTTGGTGAT AGCGCGAGAC 
GAGAGCGAGG CTGAGAAGGA GAAGCTGCAG AGGCTACCTG AGTACACCCC GCGCACCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

The epidermal growth factor receptor decreases Stathmin 1 and triggers catagen entry in the mouse.
Experimental dermatology25(4)275-81(2016 Apr)
Bichsel KJ,Hammiller B,Trempus CS,Li Y,Hansen LA

Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure.
Journal of cell science127(Pt 19)4292-307(2014 Oct)
Williamson RC,Cowell CA,Hammond CL,Bergen DJ,Roper JA,Feng Y,Rendall TC,Race PR,Bass MD

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.
Science signaling2(87)ra51(2009 Sep)
Humphries JD,Byron A,Bass MD,Craig SE,Pinney JW,Knight D,Humphries MJ

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Rcc2 cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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