| Gene Symbol | SEMA3E |
| Entrez Gene ID | 9723 |
| Full Name | semaphorin 3E |
| Synonyms | M-SEMAH,M-SemaK,SEMAH,coll-5 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]. |
| Disorder MIM: | |
| Disorder Html: | ?CHARGE syndrome, 214800 (3) |
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SEMA3E cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following SEMA3E gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SEMA3E cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu22789 Clone ID Related Accession (Same CDS sequence) NM_012431.2 , NM_012431.3 Accession Version NM_012431.2 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 2328bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1506787200000 Organism Homo sapiens(human) Product semaphorin-3E isoform 1 precursor Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB215551.1, BC152458.1, DA722912.1, BC140706.1 and AC079799.7. This sequence is a reference standard in the RefSeqGene project. On May 13, 2010 this sequence version replaced NM_012431.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB002329.1, SRR1660807.77724.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281ATGGCATCCG CGGGGCACAT TATCACCTTG CTCCTGTGGG GTTACTTACT GGAGCTTTGG
ACAGGAGGTC ATACAGCTGA TACTACCCAC CCCCGGTTAC GCCTGTCACA TAAAGAGCTC
TTGAATCTGA ACAGAACATC AATATTTCAT AGCCCTTTTG GATTTCTTGA TCTCCATACA
ATGCTGCTGG ATGAATATCA AGAGAGGCTC TTCGTGGGAG GCAGGGACCT TGTATATTCC
CTCAGCTTGG AGAGAATCAG TGACGGCTAT AAAGAGATAC ACTGGCCGAG TACAGCTCTA
AAAATGGAAG AATGCATAAT GAAGGGAAAA GATGCGGGTG AATGTGCAAA TTATGTTCGG
GTTTTGCATC ACTATAACAG GACACACCTT CTGACCTGTG GTACTGGAGC TTTTGATCCA
GTTTGTGCCT TCATCAGAGT TGGATATCAT TTGGAGGATC CTCTGTTTCA CCTGGAATCA
CCCAGATCTG AGAGAGGAAG GGGCAGATGT CCTTTTGACC CCAGCTCCTC CTTCATCTCC
ACTTTAATTG GTAGTGAATT GTTTGCTGGA CTCTACAGTG ACTACTGGAG CAGAGACGCT
GCGATCTTCC GCAGCATGGG GCGACTGGCC CATATCCGCA CTGAGCATGA CGATGAGCGT
CTGTTGAAAG AACCAAAATT TGTAGGTTCA TACATGATTC CTGACAATGA AGACAGAGAT
GACAACAAAG TATATTTCTT TTTTACTGAG AAGGCACTGG AGGCAGAAAA CAATGCTCAC
GCAATTTACA CCAGGGTCGG GCGACTCTGT GTGAATGATG TAGGAGGGCA GAGAATACTG
GTGAATAAGT GGAGCACTTT CCTAAAAGCG AGACTCGTTT GCTCAGTACC AGGAATGAAT
GGAATTGACA CATATTTTGA TGAATTAGAG GACGTTTTTT TGCTACCTAC CAGAGATCAT
AAGAATCCAG TGATATTTGG ACTCTTTAAC ACTACCAGTA ATATTTTTCG AGGGCATGCT
ATATGTGTCT ATCACATGTC TAGCATTCGG GCAGCCTTCA ACGGACCATA TGCACATAAG
GAAGGACCTG AATACCACTG GTCAGTCTAT GAAGGAAAAG TCCCTTATCC AAGGCCTGGT
TCTTGTGCCA GCAAAGTAAA TGGAGGGAGA TACGGAACCA CCAAGGACTA TCCTGATGAT
GCCATCCGAT TTGCAAGAAG TCATCCACTA ATGTACCAGG CCATAAAACC TGCCCATAAA
AAACCAATAT TGGTAAAAAC AGATGGAAAA TATAACCTGA AACAAATAGC AGTAGATCGA
GTGGAAGCTG AGGATGGCCA ATATGACGTC TTGTTTATTG GGACAGATAA TGGAATTGTG
CTGAAAGTAA TCACAATTTA CAACCAAGAA ATGGAATCAA TGGAAGAAGT AATTCTAGAA
GAACTTCAGA TATTCAAGGA TCCAGTTCCT ATTATTTCTA TGGAGATTTC TTCAAAGCGG
CAACAGCTGT ATATTGGATC TGCTTCTGCT GTGGCTCAAG TCAGATTCCA TCACTGTGAC
ATGTATGGAA GTGCTTGTGC TGACTGCTGC CTGGCTCGAG ACCCTTACTG TGCCTGGGAT
GGCATATCCT GCTCCCGGTA TTACCCAACA GGCACACATG CAAAAAGGCG TTTCCGGAGA
CAAGATGTTC GACATGGAAA TGCAGCTCAG CAGTGCTTTG GACAACAGTT TGTTGGGGAT
GCTTTGGATA AGACTGAAGA ACATCTGGCT TATGGCATAG AGAACAACAG TACTTTGCTG
GAATGTACCC CACGATCTTT ACAAGCGAAA GTTATCTGGT TTGTACAGAA AGGACGTGAG
ACAAGAAAAG AGGAGGTGAA GACAGATGAC AGAGTGGTTA AGATGGACCT TGGTTTACTC
TTCCTAAGGT TACACAAATC AGATGCTGGG ACCTATTTTT GCCAGACAGT AGAGCATAGC
TTTGTCCATA CGGTCCGTAA AATCACCTTG GAGGTAGTGG AAGAGGAGAA AGTCGAGGAT
ATGTTTAACA AGGACGATGA GGAGGACAGG CATCACAGGA TGCCTTGTCC TGCTCAGAGT
AGCATCTCGC AGGGAGCAAA ACCATGGTAC AAGGAATTCT TGCAGCTGAT CGGTTATAGC
AACTTCCAGA GAGTGGAAGA ATACTGCGAG AAAGTATGGT GCACAGATAG AAAGAGGAAA
AAGCTTAAAA TGTCACCCTC CAAGTGGAAG TATGCCAACC CTCAGGAAAA GAAGCTCCGT
TCCAAACCTG AGCATTACCG CCTGCCCAGG CACACGCTGG ACTCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_036563.1 CDS 622..2949 Translation 
Target ORF information:
RefSeq Version NM_012431.2 Organism Homo sapiens(human) Definition Homo sapiens semaphorin 3E (SEMA3E), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_012431.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281ATGGCATCCG CGGGGCACAT TATCACCTTG CTCCTGTGGG GTTACTTACT GGAGCTTTGG
ACAGGAGGTC ATACAGCTGA TACTACCCAC CCCCGGTTAC GCCTGTCACA TAAAGAGCTC
TTGAATCTGA ACAGAACATC AATATTTCAT AGCCCTTTTG GATTTCTTGA TCTCCATACA
ATGCTGCTGG ATGAATATCA AGAGAGGCTC TTCGTGGGAG GCAGGGACCT TGTATATTCC
CTCAGCTTGG AGAGAATCAG TGACGGCTAT AAAGAGATAC ACTGGCCGAG TACAGCTCTA
AAAATGGAAG AATGCATAAT GAAGGGAAAA GATGCGGGTG AATGTGCAAA TTATGTTCGG
GTTTTGCATC ACTATAACAG GACACACCTT CTGACCTGTG GTACTGGAGC TTTTGATCCA
GTTTGTGCCT TCATCAGAGT TGGATATCAT TTGGAGGATC CTCTGTTTCA CCTGGAATCA
CCCAGATCTG AGAGAGGAAG GGGCAGATGT CCTTTTGACC CCAGCTCCTC CTTCATCTCC
ACTTTAATTG GTAGTGAATT GTTTGCTGGA CTCTACAGTG ACTACTGGAG CAGAGACGCT
GCGATCTTCC GCAGCATGGG GCGACTGGCC CATATCCGCA CTGAGCATGA CGATGAGCGT
CTGTTGAAAG AACCAAAATT TGTAGGTTCA TACATGATTC CTGACAATGA AGACAGAGAT
GACAACAAAG TATATTTCTT TTTTACTGAG AAGGCACTGG AGGCAGAAAA CAATGCTCAC
GCAATTTACA CCAGGGTCGG GCGACTCTGT GTGAATGATG TAGGAGGGCA GAGAATACTG
GTGAATAAGT GGAGCACTTT CCTAAAAGCG AGACTCGTTT GCTCAGTACC AGGAATGAAT
GGAATTGACA CATATTTTGA TGAATTAGAG GACGTTTTTT TGCTACCTAC CAGAGATCAT
AAGAATCCAG TGATATTTGG ACTCTTTAAC ACTACCAGTA ATATTTTTCG AGGGCATGCT
ATATGTGTCT ATCACATGTC TAGCATTCGG GCAGCCTTCA ACGGACCATA TGCACATAAG
GAAGGACCTG AATACCACTG GTCAGTCTAT GAAGGAAAAG TCCCTTATCC AAGGCCTGGT
TCTTGTGCCA GCAAAGTAAA TGGAGGGAGA TACGGAACCA CCAAGGACTA TCCTGATGAT
GCCATCCGAT TTGCAAGAAG TCATCCACTA ATGTACCAGG CCATAAAACC TGCCCATAAA
AAACCAATAT TGGTAAAAAC AGATGGAAAA TATAACCTGA AACAAATAGC AGTAGATCGA
GTGGAAGCTG AGGATGGCCA ATATGACGTC TTGTTTATTG GGACAGATAA TGGAATTGTG
CTGAAAGTAA TCACAATTTA CAACCAAGAA ATGGAATCAA TGGAAGAAGT AATTCTAGAA
GAACTTCAGA TATTCAAGGA TCCAGTTCCT ATTATTTCTA TGGAGATTTC TTCAAAGCGG
CAACAGCTGT ATATTGGATC TGCTTCTGCT GTGGCTCAAG TCAGATTCCA TCACTGTGAC
ATGTATGGAA GTGCTTGTGC TGACTGCTGC CTGGCTCGAG ACCCTTACTG TGCCTGGGAT
GGCATATCCT GCTCCCGGTA TTACCCAACA GGCACACATG CAAAAAGGCG TTTCCGGAGA
CAAGATGTTC GACATGGAAA TGCAGCTCAG CAGTGCTTTG GACAACAGTT TGTTGGGGAT
GCTTTGGATA AGACTGAAGA ACATCTGGCT TATGGCATAG AGAACAACAG TACTTTGCTG
GAATGTACCC CACGATCTTT ACAAGCGAAA GTTATCTGGT TTGTACAGAA AGGACGTGAG
ACAAGAAAAG AGGAGGTGAA GACAGATGAC AGAGTGGTTA AGATGGACCT TGGTTTACTC
TTCCTAAGGT TACACAAATC AGATGCTGGG ACCTATTTTT GCCAGACAGT AGAGCATAGC
TTTGTCCATA CGGTCCGTAA AATCACCTTG GAGGTAGTGG AAGAGGAGAA AGTCGAGGAT
ATGTTTAACA AGGACGATGA GGAGGACAGG CATCACAGGA TGCCTTGTCC TGCTCAGAGT
AGCATCTCGC AGGGAGCAAA ACCATGGTAC AAGGAATTCT TGCAGCTGAT CGGTTATAGC
AACTTCCAGA GAGTGGAAGA ATACTGCGAG AAAGTATGGT GCACAGATAG AAAGAGGAAA
AAGCTTAAAA TGTCACCCTC CAAGTGGAAG TATGCCAACC CTCAGGAAAA GAAGCTCCGT
TCCAAACCTG AGCATTACCG CCTGCCCAGG CACACGCTGG ACTCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu22789 Clone ID Related Accession (Same CDS sequence) NM_012431.2 , NM_012431.3 Accession Version NM_012431.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 2328bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1563724800000 Organism Homo sapiens(human) Product semaphorin-3E isoform 1 precursor Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB215551.1, BC152458.1, DA722912.1, BC140706.1, AC079799.7 and AW450461.1. This sequence is a reference standard in the RefSeqGene project. On Oct 1, 2018 this sequence version replaced NM_012431.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB002329.1, BC152458.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000643230.2/ ENSP00000496491.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281ATGGCATCCG CGGGGCACAT TATCACCTTG CTCCTGTGGG GTTACTTACT GGAGCTTTGG
ACAGGAGGTC ATACAGCTGA TACTACCCAC CCCCGGTTAC GCCTGTCACA TAAAGAGCTC
TTGAATCTGA ACAGAACATC AATATTTCAT AGCCCTTTTG GATTTCTTGA TCTCCATACA
ATGCTGCTGG ATGAATATCA AGAGAGGCTC TTCGTGGGAG GCAGGGACCT TGTATATTCC
CTCAGCTTGG AGAGAATCAG TGACGGCTAT AAAGAGATAC ACTGGCCGAG TACAGCTCTA
AAAATGGAAG AATGCATAAT GAAGGGAAAA GATGCGGGTG AATGTGCAAA TTATGTTCGG
GTTTTGCATC ACTATAACAG GACACACCTT CTGACCTGTG GTACTGGAGC TTTTGATCCA
GTTTGTGCCT TCATCAGAGT TGGATATCAT TTGGAGGATC CTCTGTTTCA CCTGGAATCA
CCCAGATCTG AGAGAGGAAG GGGCAGATGT CCTTTTGACC CCAGCTCCTC CTTCATCTCC
ACTTTAATTG GTAGTGAATT GTTTGCTGGA CTCTACAGTG ACTACTGGAG CAGAGACGCT
GCGATCTTCC GCAGCATGGG GCGACTGGCC CATATCCGCA CTGAGCATGA CGATGAGCGT
CTGTTGAAAG AACCAAAATT TGTAGGTTCA TACATGATTC CTGACAATGA AGACAGAGAT
GACAACAAAG TATATTTCTT TTTTACTGAG AAGGCACTGG AGGCAGAAAA CAATGCTCAC
GCAATTTACA CCAGGGTCGG GCGACTCTGT GTGAATGATG TAGGAGGGCA GAGAATACTG
GTGAATAAGT GGAGCACTTT CCTAAAAGCG AGACTCGTTT GCTCAGTACC AGGAATGAAT
GGAATTGACA CATATTTTGA TGAATTAGAG GACGTTTTTT TGCTACCTAC CAGAGATCAT
AAGAATCCAG TGATATTTGG ACTCTTTAAC ACTACCAGTA ATATTTTTCG AGGGCATGCT
ATATGTGTCT ATCACATGTC TAGCATTCGG GCAGCCTTCA ACGGACCATA TGCACATAAG
GAAGGACCTG AATACCACTG GTCAGTCTAT GAAGGAAAAG TCCCTTATCC AAGGCCTGGT
TCTTGTGCCA GCAAAGTAAA TGGAGGGAGA TACGGAACCA CCAAGGACTA TCCTGATGAT
GCCATCCGAT TTGCAAGAAG TCATCCACTA ATGTACCAGG CCATAAAACC TGCCCATAAA
AAACCAATAT TGGTAAAAAC AGATGGAAAA TATAACCTGA AACAAATAGC AGTAGATCGA
GTGGAAGCTG AGGATGGCCA ATATGACGTC TTGTTTATTG GGACAGATAA TGGAATTGTG
CTGAAAGTAA TCACAATTTA CAACCAAGAA ATGGAATCAA TGGAAGAAGT AATTCTAGAA
GAACTTCAGA TATTCAAGGA TCCAGTTCCT ATTATTTCTA TGGAGATTTC TTCAAAGCGG
CAACAGCTGT ATATTGGATC TGCTTCTGCT GTGGCTCAAG TCAGATTCCA TCACTGTGAC
ATGTATGGAA GTGCTTGTGC TGACTGCTGC CTGGCTCGAG ACCCTTACTG TGCCTGGGAT
GGCATATCCT GCTCCCGGTA TTACCCAACA GGCACACATG CAAAAAGGCG TTTCCGGAGA
CAAGATGTTC GACATGGAAA TGCAGCTCAG CAGTGCTTTG GACAACAGTT TGTTGGGGAT
GCTTTGGATA AGACTGAAGA ACATCTGGCT TATGGCATAG AGAACAACAG TACTTTGCTG
GAATGTACCC CACGATCTTT ACAAGCGAAA GTTATCTGGT TTGTACAGAA AGGACGTGAG
ACAAGAAAAG AGGAGGTGAA GACAGATGAC AGAGTGGTTA AGATGGACCT TGGTTTACTC
TTCCTAAGGT TACACAAATC AGATGCTGGG ACCTATTTTT GCCAGACAGT AGAGCATAGC
TTTGTCCATA CGGTCCGTAA AATCACCTTG GAGGTAGTGG AAGAGGAGAA AGTCGAGGAT
ATGTTTAACA AGGACGATGA GGAGGACAGG CATCACAGGA TGCCTTGTCC TGCTCAGAGT
AGCATCTCGC AGGGAGCAAA ACCATGGTAC AAGGAATTCT TGCAGCTGAT CGGTTATAGC
AACTTCCAGA GAGTGGAAGA ATACTGCGAG AAAGTATGGT GCACAGATAG AAAGAGGAAA
AAGCTTAAAA TGTCACCCTC CAAGTGGAAG TATGCCAACC CTCAGGAAAA GAAGCTCCGT
TCCAAACCTG AGCATTACCG CCTGCCCAGG CACACGCTGG ACTCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_036563.1 CDS 598..2925 Translation
Target ORF information:
RefSeq Version NM_012431.3 Organism Homo sapiens(human) Definition Homo sapiens semaphorin 3E (SEMA3E), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_012431.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281ATGGCATCCG CGGGGCACAT TATCACCTTG CTCCTGTGGG GTTACTTACT GGAGCTTTGG
ACAGGAGGTC ATACAGCTGA TACTACCCAC CCCCGGTTAC GCCTGTCACA TAAAGAGCTC
TTGAATCTGA ACAGAACATC AATATTTCAT AGCCCTTTTG GATTTCTTGA TCTCCATACA
ATGCTGCTGG ATGAATATCA AGAGAGGCTC TTCGTGGGAG GCAGGGACCT TGTATATTCC
CTCAGCTTGG AGAGAATCAG TGACGGCTAT AAAGAGATAC ACTGGCCGAG TACAGCTCTA
AAAATGGAAG AATGCATAAT GAAGGGAAAA GATGCGGGTG AATGTGCAAA TTATGTTCGG
GTTTTGCATC ACTATAACAG GACACACCTT CTGACCTGTG GTACTGGAGC TTTTGATCCA
GTTTGTGCCT TCATCAGAGT TGGATATCAT TTGGAGGATC CTCTGTTTCA CCTGGAATCA
CCCAGATCTG AGAGAGGAAG GGGCAGATGT CCTTTTGACC CCAGCTCCTC CTTCATCTCC
ACTTTAATTG GTAGTGAATT GTTTGCTGGA CTCTACAGTG ACTACTGGAG CAGAGACGCT
GCGATCTTCC GCAGCATGGG GCGACTGGCC CATATCCGCA CTGAGCATGA CGATGAGCGT
CTGTTGAAAG AACCAAAATT TGTAGGTTCA TACATGATTC CTGACAATGA AGACAGAGAT
GACAACAAAG TATATTTCTT TTTTACTGAG AAGGCACTGG AGGCAGAAAA CAATGCTCAC
GCAATTTACA CCAGGGTCGG GCGACTCTGT GTGAATGATG TAGGAGGGCA GAGAATACTG
GTGAATAAGT GGAGCACTTT CCTAAAAGCG AGACTCGTTT GCTCAGTACC AGGAATGAAT
GGAATTGACA CATATTTTGA TGAATTAGAG GACGTTTTTT TGCTACCTAC CAGAGATCAT
AAGAATCCAG TGATATTTGG ACTCTTTAAC ACTACCAGTA ATATTTTTCG AGGGCATGCT
ATATGTGTCT ATCACATGTC TAGCATTCGG GCAGCCTTCA ACGGACCATA TGCACATAAG
GAAGGACCTG AATACCACTG GTCAGTCTAT GAAGGAAAAG TCCCTTATCC AAGGCCTGGT
TCTTGTGCCA GCAAAGTAAA TGGAGGGAGA TACGGAACCA CCAAGGACTA TCCTGATGAT
GCCATCCGAT TTGCAAGAAG TCATCCACTA ATGTACCAGG CCATAAAACC TGCCCATAAA
AAACCAATAT TGGTAAAAAC AGATGGAAAA TATAACCTGA AACAAATAGC AGTAGATCGA
GTGGAAGCTG AGGATGGCCA ATATGACGTC TTGTTTATTG GGACAGATAA TGGAATTGTG
CTGAAAGTAA TCACAATTTA CAACCAAGAA ATGGAATCAA TGGAAGAAGT AATTCTAGAA
GAACTTCAGA TATTCAAGGA TCCAGTTCCT ATTATTTCTA TGGAGATTTC TTCAAAGCGG
CAACAGCTGT ATATTGGATC TGCTTCTGCT GTGGCTCAAG TCAGATTCCA TCACTGTGAC
ATGTATGGAA GTGCTTGTGC TGACTGCTGC CTGGCTCGAG ACCCTTACTG TGCCTGGGAT
GGCATATCCT GCTCCCGGTA TTACCCAACA GGCACACATG CAAAAAGGCG TTTCCGGAGA
CAAGATGTTC GACATGGAAA TGCAGCTCAG CAGTGCTTTG GACAACAGTT TGTTGGGGAT
GCTTTGGATA AGACTGAAGA ACATCTGGCT TATGGCATAG AGAACAACAG TACTTTGCTG
GAATGTACCC CACGATCTTT ACAAGCGAAA GTTATCTGGT TTGTACAGAA AGGACGTGAG
ACAAGAAAAG AGGAGGTGAA GACAGATGAC AGAGTGGTTA AGATGGACCT TGGTTTACTC
TTCCTAAGGT TACACAAATC AGATGCTGGG ACCTATTTTT GCCAGACAGT AGAGCATAGC
TTTGTCCATA CGGTCCGTAA AATCACCTTG GAGGTAGTGG AAGAGGAGAA AGTCGAGGAT
ATGTTTAACA AGGACGATGA GGAGGACAGG CATCACAGGA TGCCTTGTCC TGCTCAGAGT
AGCATCTCGC AGGGAGCAAA ACCATGGTAC AAGGAATTCT TGCAGCTGAT CGGTTATAGC
AACTTCCAGA GAGTGGAAGA ATACTGCGAG AAAGTATGGT GCACAGATAG AAAGAGGAAA
AAGCTTAAAA TGTCACCCTC CAAGTGGAAG TATGCCAACC CTCAGGAAAA GAAGCTCCGT
TCCAAACCTG AGCATTACCG CCTGCCCAGG CACACGCTGG ACTCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu12649 Clone ID Related Accession (Same CDS sequence) NM_001178129.1 Accession Version NM_001178129.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 2148bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1563724800000 Organism Homo sapiens(human) Product semaphorin-3E isoform 2 Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK303925.1, BC152458.1 and AC079799.7. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK303925.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2467144 [ECO:0000350] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101ATGCTGCTGG ATGAATATCA AGAGAGGCTC TTCGTGGGAG GCAGGGACCT TGTATATTCC
CTCAGCTTGG AGAGAATCAG TGACGGCTAT AAAGAGATAC ACTGGCCGAG TACAGCTCTA
AAAATGGAAG AATGCATAAT GAAGGGAAAA GATGCGGGTG AATGTGCAAA TTATGTTCGG
GTTTTGCATC ACTATAACAG GACACACCTT CTGACCTGTG GTACTGGAGC TTTTGATCCA
GTTTGTGCCT TCATCAGAGT TGGATATCAT TTGGAGGATC CTCTGTTTCA CCTGGAATCA
CCCAGATCTG AGAGAGGAAG GGGCAGATGT CCTTTTGACC CCAGCTCCTC CTTCATCTCC
ACTTTAATTG GTAGTGAATT GTTTGCTGGA CTCTACAGTG ACTACTGGAG CAGAGACGCT
GCGATCTTCC GCAGCATGGG GCGACTGGCC CATATCCGCA CTGAGCATGA CGATGAGCGT
CTGTTGAAAG AACCAAAATT TGTAGGTTCA TACATGATTC CTGACAATGA AGACAGAGAT
GACAACAAAG TATATTTCTT TTTTACTGAG AAGGCACTGG AGGCAGAAAA CAATGCTCAC
GCAATTTACA CCAGGGTCGG GCGACTCTGT GTGAATGATG TAGGAGGGCA GAGAATACTG
GTGAATAAGT GGAGCACTTT CCTAAAAGCG AGACTCGTTT GCTCAGTACC AGGAATGAAT
GGAATTGACA CATATTTTGA TGAATTAGAG GACGTTTTTT TGCTACCTAC CAGAGATCAT
AAGAATCCAG TGATATTTGG ACTCTTTAAC ACTACCAGTA ATATTTTTCG AGGGCATGCT
ATATGTGTCT ATCACATGTC TAGCATTCGG GCAGCCTTCA ACGGACCATA TGCACATAAG
GAAGGACCTG AATACCACTG GTCAGTCTAT GAAGGAAAAG TCCCTTATCC AAGGCCTGGT
TCTTGTGCCA GCAAAGTAAA TGGAGGGAGA TACGGAACCA CCAAGGACTA TCCTGATGAT
GCCATCCGAT TTGCAAGAAG TCATCCACTA ATGTACCAGG CCATAAAACC TGCCCATAAA
AAACCAATAT TGGTAAAAAC AGATGGAAAA TATAACCTGA AACAAATAGC AGTAGATCGA
GTGGAAGCTG AGGATGGCCA ATATGACGTC TTGTTTATTG GGACAGATAA TGGAATTGTG
CTGAAAGTAA TCACAATTTA CAACCAAGAA ATGGAATCAA TGGAAGAAGT AATTCTAGAA
GAACTTCAGA TATTCAAGGA TCCAGTTCCT ATTATTTCTA TGGAGATTTC TTCAAAGCGG
CAACAGCTGT ATATTGGATC TGCTTCTGCT GTGGCTCAAG TCAGATTCCA TCACTGTGAC
ATGTATGGAA GTGCTTGTGC TGACTGCTGC CTGGCTCGAG ACCCTTACTG TGCCTGGGAT
GGCATATCCT GCTCCCGGTA TTACCCAACA GGCACACATG CAAAAAGGCG TTTCCGGAGA
CAAGATGTTC GACATGGAAA TGCAGCTCAG CAGTGCTTTG GACAACAGTT TGTTGGGGAT
GCTTTGGATA AGACTGAAGA ACATCTGGCT TATGGCATAG AGAACAACAG TACTTTGCTG
GAATGTACCC CACGATCTTT ACAAGCGAAA GTTATCTGGT TTGTACAGAA AGGACGTGAG
ACAAGAAAAG AGGAGGTGAA GACAGATGAC AGAGTGGTTA AGATGGACCT TGGTTTACTC
TTCCTAAGGT TACACAAATC AGATGCTGGG ACCTATTTTT GCCAGACAGT AGAGCATAGC
TTTGTCCATA CGGTCCGTAA AATCACCTTG GAGGTAGTGG AAGAGGAGAA AGTCGAGGAT
ATGTTTAACA AGGACGATGA GGAGGACAGG CATCACAGGA TGCCTTGTCC TGCTCAGAGT
AGCATCTCGC AGGGAGCAAA ACCATGGTAC AAGGAATTCT TGCAGCTGAT CGGTTATAGC
AACTTCCAGA GAGTGGAAGA ATACTGCGAG AAAGTATGGT GCACAGATAG AAAGAGGAAA
AAGCTTAAAA TGTCACCCTC CAAGTGGAAG TATGCCAACC CTCAGGAAAA GAAGCTCCGT
TCCAAACCTG AGCATTACCG CCTGCCCAGG CACACGCTGG ACTCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001171600.1 CDS 166..2313 Translation
Target ORF information:
RefSeq Version NM_001178129.1 Organism Homo sapiens(human) Definition Homo sapiens semaphorin 3E (SEMA3E), transcript variant 2, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_001178129.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101ATGCTGCTGG ATGAATATCA AGAGAGGCTC TTCGTGGGAG GCAGGGACCT TGTATATTCC
CTCAGCTTGG AGAGAATCAG TGACGGCTAT AAAGAGATAC ACTGGCCGAG TACAGCTCTA
AAAATGGAAG AATGCATAAT GAAGGGAAAA GATGCGGGTG AATGTGCAAA TTATGTTCGG
GTTTTGCATC ACTATAACAG GACACACCTT CTGACCTGTG GTACTGGAGC TTTTGATCCA
GTTTGTGCCT TCATCAGAGT TGGATATCAT TTGGAGGATC CTCTGTTTCA CCTGGAATCA
CCCAGATCTG AGAGAGGAAG GGGCAGATGT CCTTTTGACC CCAGCTCCTC CTTCATCTCC
ACTTTAATTG GTAGTGAATT GTTTGCTGGA CTCTACAGTG ACTACTGGAG CAGAGACGCT
GCGATCTTCC GCAGCATGGG GCGACTGGCC CATATCCGCA CTGAGCATGA CGATGAGCGT
CTGTTGAAAG AACCAAAATT TGTAGGTTCA TACATGATTC CTGACAATGA AGACAGAGAT
GACAACAAAG TATATTTCTT TTTTACTGAG AAGGCACTGG AGGCAGAAAA CAATGCTCAC
GCAATTTACA CCAGGGTCGG GCGACTCTGT GTGAATGATG TAGGAGGGCA GAGAATACTG
GTGAATAAGT GGAGCACTTT CCTAAAAGCG AGACTCGTTT GCTCAGTACC AGGAATGAAT
GGAATTGACA CATATTTTGA TGAATTAGAG GACGTTTTTT TGCTACCTAC CAGAGATCAT
AAGAATCCAG TGATATTTGG ACTCTTTAAC ACTACCAGTA ATATTTTTCG AGGGCATGCT
ATATGTGTCT ATCACATGTC TAGCATTCGG GCAGCCTTCA ACGGACCATA TGCACATAAG
GAAGGACCTG AATACCACTG GTCAGTCTAT GAAGGAAAAG TCCCTTATCC AAGGCCTGGT
TCTTGTGCCA GCAAAGTAAA TGGAGGGAGA TACGGAACCA CCAAGGACTA TCCTGATGAT
GCCATCCGAT TTGCAAGAAG TCATCCACTA ATGTACCAGG CCATAAAACC TGCCCATAAA
AAACCAATAT TGGTAAAAAC AGATGGAAAA TATAACCTGA AACAAATAGC AGTAGATCGA
GTGGAAGCTG AGGATGGCCA ATATGACGTC TTGTTTATTG GGACAGATAA TGGAATTGTG
CTGAAAGTAA TCACAATTTA CAACCAAGAA ATGGAATCAA TGGAAGAAGT AATTCTAGAA
GAACTTCAGA TATTCAAGGA TCCAGTTCCT ATTATTTCTA TGGAGATTTC TTCAAAGCGG
CAACAGCTGT ATATTGGATC TGCTTCTGCT GTGGCTCAAG TCAGATTCCA TCACTGTGAC
ATGTATGGAA GTGCTTGTGC TGACTGCTGC CTGGCTCGAG ACCCTTACTG TGCCTGGGAT
GGCATATCCT GCTCCCGGTA TTACCCAACA GGCACACATG CAAAAAGGCG TTTCCGGAGA
CAAGATGTTC GACATGGAAA TGCAGCTCAG CAGTGCTTTG GACAACAGTT TGTTGGGGAT
GCTTTGGATA AGACTGAAGA ACATCTGGCT TATGGCATAG AGAACAACAG TACTTTGCTG
GAATGTACCC CACGATCTTT ACAAGCGAAA GTTATCTGGT TTGTACAGAA AGGACGTGAG
ACAAGAAAAG AGGAGGTGAA GACAGATGAC AGAGTGGTTA AGATGGACCT TGGTTTACTC
TTCCTAAGGT TACACAAATC AGATGCTGGG ACCTATTTTT GCCAGACAGT AGAGCATAGC
TTTGTCCATA CGGTCCGTAA AATCACCTTG GAGGTAGTGG AAGAGGAGAA AGTCGAGGAT
ATGTTTAACA AGGACGATGA GGAGGACAGG CATCACAGGA TGCCTTGTCC TGCTCAGAGT
AGCATCTCGC AGGGAGCAAA ACCATGGTAC AAGGAATTCT TGCAGCTGAT CGGTTATAGC
AACTTCCAGA GAGTGGAAGA ATACTGCGAG AAAGTATGGT GCACAGATAG AAAGAGGAAA
AAGCTTAAAA TGTCACCCTC CAAGTGGAAG TATGCCAACC CTCAGGAAAA GAAGCTCCGT
TCCAAACCTG AGCATTACCG CCTGCCCAGG CACACGCTGG ACTCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
-
PubMed
The regulatory role of semaphorin 3E in allergic asthma.
The international journal of biochemistry & cell biology10668-73(2019 01)
Movassagh H,Koussih L,Shan L,Gounni AS
Expression of semaphorin 3E is suppressed in severe asthma.
The Journal of allergy and clinical immunology140(4)1176-1179(2017 10)
Movassagh H,Shan L,Chakir J,McConville JF,Halayko AJ,Koussih L,Gounni AS
Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In Vivo.
Journal of immunology (Baltimore, Md. : 1950)198(3)1023-1033(2017 02)
Movassagh H,Saati A,Nandagopal S,Mohammed A,Tatari N,Shan L,Duke-Cohan JS,Fowke KR,Lin F,Gounni AS
Association of Increased Serum Sema3E with TRIB3 Q84R Polymorphism and Carotid Atherosclerosis in Metabolic Syndrome.
Annals of clinical and laboratory science47(1)47-51(2017 Jan)
Qin RR,Song M,Li YH,Wang F,Zhou HM,Liu MH,Zhong M,Zhang Y,Zhang W,Wang ZH
Overexpression of Semaphorin-3E enhances pancreatic cancer cell growth and associates with poor patient survival.
Oncotarget7(52)87431-87448(2016 Dec)
Yong LK,Lai S,Liang Z,Poteet E,Chen F,van Buren G,Fisher W,Mo Q,Chen C,Yao Q
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