AQR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AQR
Entrez Gene ID	9716
Full Name	aquarius intron-binding spliceosomal factor
Synonyms	IBP160,fSAP164
General protein information	Preferred Names aquarius intron-binding spliceosomal factor Names intron-binding protein aquarius aquarius homolog functional spliceosome-associated protein 164 intron-binding protein of 160 kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q14
Disorder MIM:	610548

mRNA and Protein(s)

mRNA	Protein	Name
NM_014691.2	NP_055506.1	intron-binding protein aquarius
NM_014691.3	NP_055506.1	RNA helicase aquarius

Pathways from BioSystems

Homologies

Neurospora crassa	NCU07866	XP_963127.1
Macaca mulatta (Rhesus monkey)	AQR	XP_001089350.2
Homo sapiens (human)	AQR	NP_055506.1
Arabidopsis thaliana (thale cress)	EMB2765	NP_850297.1
Oryza sativa (rice)	Os03g0387000	NP_001050258.1
Magnaporthe oryzae (rice blast fungus)	MGG_06395	XP_003717176.1
Bos taurus (cattle)	AQR	NP_001091560.1
Gallus gallus (chicken)	AQR	XP_421216.4
Danio rerio (zebrafish)	aqr	NP_956758.2
Canis lupus familiaris (dog)	AQR	XP_535425.3
Mus musculus (house mouse)	Aqr	NP_033832.2
Caenorhabditis elegans (roundworm)	emb-4	NP_001256831.1
Xenopus tropicalis (tropical clawed frog)	aqr	XP_002932889.2
Pan troglodytes (chimpanzee)	AQR	XP_510286.3
Rattus norvegicus (Norway rat)	Aqr	NP_001094457.1
Drosophila melanogaster (fruit fly)	CG31368	NP_996198.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004028	XP_003436690.1

Gene Ontology
Bibliography

Related articles in PubMed

AQR is a novel type 2 diabetes-associated gene that regulates signaling pathways critical for glucose metabolism.
Song C, Yan H, Wang H, Zhang Y, Cao H, Wan Y, Kong L, Chen S, Xu H, Pan B, Zhang J, Fan G, Xin H, Liang Z, Jia W, Tian XL
Journal of genetics and genomics = Yi chuan xue bao45(2)111-120(2018 02)

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Lührmann R
Nature542(7641)318-323(2017 02)

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes.
De I, Bessonov S, Hofele R, dos Santos K, Will CL, Urlaub H, Lührmann R, Pena V
Nature structural & molecular biology22(2)138-44(2015 Feb)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanhäusser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AQR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AQR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu107624	NM_014691.3 Latest version!	Homo sapiens aquarius intron-binding spliceosomal factor (AQR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OHu06634	NM_014691.2 Latest version!	Homo sapiens aquarius intron-binding spliceosomal factor (AQR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$384.30 $549.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AQR ( NM_014691.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055506.1 Homo sapiens aquarius intron-binding spliceosomal factor (AQR), mRNA.

Price & Availability↑

CloneID	OHu107624
Clone ID Related Accession (Same CDS sequence)	NM_014691.3
Accession Version	NM_014691.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1561910400000
Organism	Homo sapiens(human)
Product	RNA helicase aquarius
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018868.4. On Nov 23, 2018 this sequence version replaced NM_014691.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.51066.1, SRR1660807.30390.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000156471.10/ ENSP00000156471.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGCCC CTGCGCAGCC CAAGAAGATC GTGGCCCCTA CGGTGTCCCA AATCAATGCG 
GAGTTCGTGA CCCAGTTAGC ATGTAAATAC TGGGCTCCCC ACATCAAGAA GAAATCACCT 
TTTGATATAA AGGTTATTGA AGATATATAT GAAAAAGAGA TTGTCAAATC AAGGTTTGCT 
ATTAGAAAGA TAATGCTCTT GGAATTTAGC CAGTATCTTG AAAATTATCT CTGGATGAAT 
TATTCTCCTG AGGTATCTAG CAAGGCCTAT TTAATGTCAA TCTGCTGTAT GGTGAATGAG 
AAGTTTAGAG AAAACGTGCC TGCATGGGAG ATTTTTAAGA AGAAGCCAGA CCACTTCCCA 
TTCTTTTTTA AACACATCTT GAAGGCGGCA TTAGCTGAAA CTGATGGTGA ATTTTCACTT 
CATGAACAGA CAGTCTTACT ACTTTTTCTT GATCATTGCT TCAATAGTTT GGAAGTAGAC 
TTGATACGAA GTCAAGTACA GCAGCTTATC TCCCTCCCAA TGTGGATGGG CTTACAGCTG 
GCACGATTGG AATTAGAATT AAAAAAGACA CCTAAGCTAA GAAAATTCTG GAACTTGATT 
AAAAAGAATG ATGAAAAGAT GGATCCAGAA GCAAGAGAAC AGGCATATCA AGAGAGGAGA 
TTTCTTTCAC AACTCATCCA GAAGTTTATC TCTGTGCTGA AATCAGTCCC ACTTTCTGAA 
CCTGTCACTA TGGACAAAGT TCATTACTGT GAAAGATTCA TTGAACTTAT GATTGATCTA 
GAGGCCCTGC TACCCACAAG GCGCTGGTTT AATACCATCC TGGATGATTC CCACCTTCTG 
GTTCACTGTT ACCTTTCCAA TCTTGTTCGT AGAGAAGAGG ATGGCCATCT TTTTTCCCAG 
CTTTTGGACA TGCTTAAATT CTATACTGGT TTTGAAATTA ATGACCAAAC TGGAAATGCT 
CTGACAGAGA ATGAGATGAC CACAATTCAC TATGATAGAA TTACTTCTCT ACAGAGAGCT 
GCTTTTGCAC ATTTTCCTGA ACTCTATGAT TTTGCCCTCT CAAATGTGGC AGAAGTAGAT 
ACTCGGGAGT CCTTGGTCAA GTTTTTTGGA CCTCTTAGTT CAAACACACT CCACCAGGTG 
GCATCATACC TCTGCTTGTT GCCAACTCTT CCTAAAAATG AAGACACAAC TTTTGATAAA 
GAATTTCTTC TAGAATTGCT GGTATCTCGT CATGAACGTC GAATTTCTCA GATTCAGCAG 
TTGAACCAGA TGCCTTTGTA TCCAACTGAG AAAATTATAT GGGATGAAAA TATTGTCCCA 
ACTGAGTACT ATTCTGGAGA AGGTTGTCTT GCTCTTCCCA AATTGAATTT GCAGTTTTTG 
ACTCTTCATG ACTACCTGCT AAGGAACTTT AACCTCTTCC GCTTAGAATC AACTTATGAA 
ATTCGTCAGG ACATTGAAGA TAGTGTCAGC AGAATGAAGC CATGGCAATC TGAATATGGC 
GGTGTAGTGT TTGGTGGTTG GGCGCGAATG GCCCAGCCCA TTGTGGCTTT CACTGTCGTT 
GAAGTGGCCA AACCCAACAT AGGTGAAAAC TGGCCAACCC GAGTTCGTGC AGATGTTACC 
ATAAATCTCA ATGTCAGAGA TCACATCAAA GATGAATGGG AAGGTCTTCG TAAGCATGAT 
GTATGCTTTT TAATTACCGT ACGTCCCACA AAACCTTATG GCACTAAGTT TGACCGGAGG 
AGACCTTTTA TTGAGCAGGT TGGCCTGGTT TATGTCAGAG GCTGTGAAAT TCAGGGCATG 
CTGGATGATA AAGGACGTGT CATTGAAGAT GGACCTGAAC CCAGACCCAA TCTTAGAGGA 
GAATCAAGGA CATTTAGAGT GTTTTTGGAT CCAAACCAGT ATCAACAAGA TATGACCAAT 
ACTATACAAA ATGGAGCAGA GGATGTGTAT GAAACTTTTA ATATAATAAT GAGGAGAAAA 
CCAAAGGAAA ATAACTTTAA GGCTGTGCTG GAGACTATTC GGAACCTGAT GAATACTGAT 
TGTGTGGTAC CTGACTGGCT GCACGATATC ATTTTAGGTT ATGGGGACCC AAGTAGTGCA 
CATTATTCGA AAATGCCCAA TCAGATTGCC ACCCTTGATT TCAATGATAC ATTTCTCTCC 
ATTGAGCATT TAAAAGCCAG CTTCCCTGGT CATAATGTTA AAGTAACTGT AGAAGACCCT 
GCTCTACAAA TACCCCCTTT CAGGATAACT TTTCCAGTAA GAAGTGGAAA AGGGAAGAAA 
AGGAAAGATG CGGATGTGGA AGATGAAGAC ACCGAGGAAG CAAAAACCTT AATTGTTGAG 
CCCCATGTTA TTCCTAATAG GGGTCCTTAT CCTTATAATC AACCCAAACG TAATACGATT 
CAGTTCACTC ATACACAGAT AGAAGCCATC CGTGCTGGAA TGCAGCCTGG GCTGACTATG 
GTTGTGGGCC CACCTGGTAC AGGCAAAACA GATGTGGCAG TTCAGATCAT ATCCAACATC 
TACCACAACT TCCCAGAACA GAGGACTCTA ATTGTTACTC ATTCCAATCA GGCCCTAAAC 
CAGTTGTTTG AGAAAATCAT GGCATTAGAC ATTGATGAGC GCCACCTACT GCGTCTTGGT 
CATGGAGAAG AAGAGCTGGA GACAGAGAAA GATTTCAGCA GGTATGGAAG AGTTAATTAT 
GTTCTGGCTC GAAGAATAGA ACTTTTAGAA GAAGTCAAAC GATTGCAAAA GAGTCTAGGG 
GTTCCAGGAG ATGCCTCATA TACCTGTGAA ACTGCAGGCT ATTTCTTCTT ATACCAGGTA 
ATGTCTCGCT GGGAAGAGTA TATCAGCAAA GTGAAAAATA AAGGTAGTAC ATTGCCAGAT 
GTTACGGAAG TCTCCACTTT CTTCCCTTTC CATGAATACT TTGCAAATGC TCCTCAACCC 
ATTTTTAAAG GAAGATCTTA TGAAGAAGAC ATGGAAATTG CTGAAGGATG TTTCAGGCAT 
ATTAAGAAAA TCTTTACGCA GCTTGAGGAA TTCAGAGCCT CTGAATTGCT TCGAAGTGGA 
CTGGACAGAT CTAAATACCT TTTAGTGAAA GAAGCCAAAA TTATTGCTAT GACCTGTACT 
CATGCTGCCT TAAAACGACA TGACTTGGTC AAGCTAGGTT TCAAGTATGA CAACATTTTG 
ATGGAAGAGG CTGCTCAGAT TCTGGAGATA GAAACTTTTA TCCCTCTTCT TCTACAGAAT 
CCTCAGGATG GATTTAGCCG ACTAAAACGA TGGATTATGA TTGGCGATCA TCACCAGTTA 
CCTCCAGTTA TTAAGAACAT GGCCTTTCAA AAGTACTCAA ACATGGAGCA GTCTCTCTTC 
ACTCGCTTTG TTCGCGTTGG AGTTCCGACT GTTGACCTTG ATGCTCAAGG GAGAGCCAGA 
GCAAGCTTGT GCAACCTCTA CAACTGGCGA TACAAGAATC TAGGAAACTT ACCCCATGTG 
CAGCTCTTGC CAGAGTTTAG TACAGCAAAT GCTGGCTTAC TGTATGACTT CCAGCTCATT 
AATGTTGAAG ATTTTCAAGG AGTGGGAGAA TCTGAACCTA ATCCTTACTT CTATCAGAAT 
CTTGGAGAGG CAGAATATGT AGTAGCACTT TTTATGTACA TGTGTTTACT TGGTTACCCT 
GCTGACAAAA TCAGTATTCT AACAACATAT AATGGCCAAA AGCATCTTAT TCGCGACATC 
ATCAATAGAC GATGTGGAAA CAATCCATTG ATTGGAAGAC CAAACAAGGT GACAACTGTT 
GATAGATTTC AAGGTCAACA GAATGACTAT ATTCTTCTTT CTCTGGTACG AACCAGGGCA 
GTGGGCCATC TGAGGGATGT CCGTCGCTTG GTAGTGGCCA TGTCTAGAGC CAGACTTGGA 
CTTTATATCT TCGCCAGAGT ATCCCTCTTC CAAAACTGTT TTGAACTGAC TCCAGCTTTC 
AGTCAGCTCA CAGCTCGCCC CCTTCATTTG CATATAATTC CAACAGAACC TTTCCCAACT 
ACTAGAAAGA ATGGAGAGAG ACCATCTCAT GAAGTACAAA TAATAAAAAA TATGCCCCAG 
ATGGCAAACT TTGTATACAA CATGTACATG CATTTGATAC AGACTACACA TCATTATCAT 
CAGACTTTAT TACAACTACC ACCTGCTATG GTAGAAGAGG GTGAGGAAGT TCAAAATCAA 
GAAACAGAAT TGGAAACAGA AGAAGAGGCC ATGACTGTTC AAGCTGACAT CATACCCAGT 
CCAACAGACA CCAGCTGCCG TCAAGAAACT CCAGCCTTTC AAACTGACAC CACCCCCAGT 
GAGACAGGAG CCACTTCCAC TCCAGAAGCC ATCCCTGCTT TATCTGAGAC CACCCCTACT 
GTGGTAGGAG CTGTATCTGC ACCGGCAGAA GCTAACACAC CTCAGGATGC CACATCTGCC 
CCGGAAGAGA CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055506.1
CDS	130..4587
Translation	MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKVIEDIYEKEIVKSRFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPDHFPFFFKHILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADIIPSPTDTSCRQETPAFQTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK

Target ORF information:

RefSeq Version	NM_014691.3
Organism	Homo sapiens(human)
Definition	Homo sapiens aquarius intron-binding spliceosomal factor (AQR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014691.3

ORF Insert Sequence:

ATGGCAGCCC CTGCGCAGCC CAAGAAGATC GTGGCCCCTA CGGTGTCCCA AATCAATGCG 
GAGTTCGTGA CCCAGTTAGC ATGTAAATAC TGGGCTCCCC ACATCAAGAA GAAATCACCT 
TTTGATATAA AGGTTATTGA AGATATATAT GAAAAAGAGA TTGTCAAATC AAGGTTTGCT 
ATTAGAAAGA TAATGCTCTT GGAATTTAGC CAGTATCTTG AAAATTATCT CTGGATGAAT 
TATTCTCCTG AGGTATCTAG CAAGGCCTAT TTAATGTCAA TCTGCTGTAT GGTGAATGAG 
AAGTTTAGAG AAAACGTGCC TGCATGGGAG ATTTTTAAGA AGAAGCCAGA CCACTTCCCA 
TTCTTTTTTA AACACATCTT GAAGGCGGCA TTAGCTGAAA CTGATGGTGA ATTTTCACTT 
CATGAACAGA CAGTCTTACT ACTTTTTCTT GATCATTGCT TCAATAGTTT GGAAGTAGAC 
TTGATACGAA GTCAAGTACA GCAGCTTATC TCCCTCCCAA TGTGGATGGG CTTACAGCTG 
GCACGATTGG AATTAGAATT AAAAAAGACA CCTAAGCTAA GAAAATTCTG GAACTTGATT 
AAAAAGAATG ATGAAAAGAT GGATCCAGAA GCAAGAGAAC AGGCATATCA AGAGAGGAGA 
TTTCTTTCAC AACTCATCCA GAAGTTTATC TCTGTGCTGA AATCAGTCCC ACTTTCTGAA 
CCTGTCACTA TGGACAAAGT TCATTACTGT GAAAGATTCA TTGAACTTAT GATTGATCTA 
GAGGCCCTGC TACCCACAAG GCGCTGGTTT AATACCATCC TGGATGATTC CCACCTTCTG 
GTTCACTGTT ACCTTTCCAA TCTTGTTCGT AGAGAAGAGG ATGGCCATCT TTTTTCCCAG 
CTTTTGGACA TGCTTAAATT CTATACTGGT TTTGAAATTA ATGACCAAAC TGGAAATGCT 
CTGACAGAGA ATGAGATGAC CACAATTCAC TATGATAGAA TTACTTCTCT ACAGAGAGCT 
GCTTTTGCAC ATTTTCCTGA ACTCTATGAT TTTGCCCTCT CAAATGTGGC AGAAGTAGAT 
ACTCGGGAGT CCTTGGTCAA GTTTTTTGGA CCTCTTAGTT CAAACACACT CCACCAGGTG 
GCATCATACC TCTGCTTGTT GCCAACTCTT CCTAAAAATG AAGACACAAC TTTTGATAAA 
GAATTTCTTC TAGAATTGCT GGTATCTCGT CATGAACGTC GAATTTCTCA GATTCAGCAG 
TTGAACCAGA TGCCTTTGTA TCCAACTGAG AAAATTATAT GGGATGAAAA TATTGTCCCA 
ACTGAGTACT ATTCTGGAGA AGGTTGTCTT GCTCTTCCCA AATTGAATTT GCAGTTTTTG 
ACTCTTCATG ACTACCTGCT AAGGAACTTT AACCTCTTCC GCTTAGAATC AACTTATGAA 
ATTCGTCAGG ACATTGAAGA TAGTGTCAGC AGAATGAAGC CATGGCAATC TGAATATGGC 
GGTGTAGTGT TTGGTGGTTG GGCGCGAATG GCCCAGCCCA TTGTGGCTTT CACTGTCGTT 
GAAGTGGCCA AACCCAACAT AGGTGAAAAC TGGCCAACCC GAGTTCGTGC AGATGTTACC 
ATAAATCTCA ATGTCAGAGA TCACATCAAA GATGAATGGG AAGGTCTTCG TAAGCATGAT 
GTATGCTTTT TAATTACCGT ACGTCCCACA AAACCTTATG GCACTAAGTT TGACCGGAGG 
AGACCTTTTA TTGAGCAGGT TGGCCTGGTT TATGTCAGAG GCTGTGAAAT TCAGGGCATG 
CTGGATGATA AAGGACGTGT CATTGAAGAT GGACCTGAAC CCAGACCCAA TCTTAGAGGA 
GAATCAAGGA CATTTAGAGT GTTTTTGGAT CCAAACCAGT ATCAACAAGA TATGACCAAT 
ACTATACAAA ATGGAGCAGA GGATGTGTAT GAAACTTTTA ATATAATAAT GAGGAGAAAA 
CCAAAGGAAA ATAACTTTAA GGCTGTGCTG GAGACTATTC GGAACCTGAT GAATACTGAT 
TGTGTGGTAC CTGACTGGCT GCACGATATC ATTTTAGGTT ATGGGGACCC AAGTAGTGCA 
CATTATTCGA AAATGCCCAA TCAGATTGCC ACCCTTGATT TCAATGATAC ATTTCTCTCC 
ATTGAGCATT TAAAAGCCAG CTTCCCTGGT CATAATGTTA AAGTAACTGT AGAAGACCCT 
GCTCTACAAA TACCCCCTTT CAGGATAACT TTTCCAGTAA GAAGTGGAAA AGGGAAGAAA 
AGGAAAGATG CGGATGTGGA AGATGAAGAC ACCGAGGAAG CAAAAACCTT AATTGTTGAG 
CCCCATGTTA TTCCTAATAG GGGTCCTTAT CCTTATAATC AACCCAAACG TAATACGATT 
CAGTTCACTC ATACACAGAT AGAAGCCATC CGTGCTGGAA TGCAGCCTGG GCTGACTATG 
GTTGTGGGCC CACCTGGTAC AGGCAAAACA GATGTGGCAG TTCAGATCAT ATCCAACATC 
TACCACAACT TCCCAGAACA GAGGACTCTA ATTGTTACTC ATTCCAATCA GGCCCTAAAC 
CAGTTGTTTG AGAAAATCAT GGCATTAGAC ATTGATGAGC GCCACCTACT GCGTCTTGGT 
CATGGAGAAG AAGAGCTGGA GACAGAGAAA GATTTCAGCA GGTATGGAAG AGTTAATTAT 
GTTCTGGCTC GAAGAATAGA ACTTTTAGAA GAAGTCAAAC GATTGCAAAA GAGTCTAGGG 
GTTCCAGGAG ATGCCTCATA TACCTGTGAA ACTGCAGGCT ATTTCTTCTT ATACCAGGTA 
ATGTCTCGCT GGGAAGAGTA TATCAGCAAA GTGAAAAATA AAGGTAGTAC ATTGCCAGAT 
GTTACGGAAG TCTCCACTTT CTTCCCTTTC CATGAATACT TTGCAAATGC TCCTCAACCC 
ATTTTTAAAG GAAGATCTTA TGAAGAAGAC ATGGAAATTG CTGAAGGATG TTTCAGGCAT 
ATTAAGAAAA TCTTTACGCA GCTTGAGGAA TTCAGAGCCT CTGAATTGCT TCGAAGTGGA 
CTGGACAGAT CTAAATACCT TTTAGTGAAA GAAGCCAAAA TTATTGCTAT GACCTGTACT 
CATGCTGCCT TAAAACGACA TGACTTGGTC AAGCTAGGTT TCAAGTATGA CAACATTTTG 
ATGGAAGAGG CTGCTCAGAT TCTGGAGATA GAAACTTTTA TCCCTCTTCT TCTACAGAAT 
CCTCAGGATG GATTTAGCCG ACTAAAACGA TGGATTATGA TTGGCGATCA TCACCAGTTA 
CCTCCAGTTA TTAAGAACAT GGCCTTTCAA AAGTACTCAA ACATGGAGCA GTCTCTCTTC 
ACTCGCTTTG TTCGCGTTGG AGTTCCGACT GTTGACCTTG ATGCTCAAGG GAGAGCCAGA 
GCAAGCTTGT GCAACCTCTA CAACTGGCGA TACAAGAATC TAGGAAACTT ACCCCATGTG 
CAGCTCTTGC CAGAGTTTAG TACAGCAAAT GCTGGCTTAC TGTATGACTT CCAGCTCATT 
AATGTTGAAG ATTTTCAAGG AGTGGGAGAA TCTGAACCTA ATCCTTACTT CTATCAGAAT 
CTTGGAGAGG CAGAATATGT AGTAGCACTT TTTATGTACA TGTGTTTACT TGGTTACCCT 
GCTGACAAAA TCAGTATTCT AACAACATAT AATGGCCAAA AGCATCTTAT TCGCGACATC 
ATCAATAGAC GATGTGGAAA CAATCCATTG ATTGGAAGAC CAAACAAGGT GACAACTGTT 
GATAGATTTC AAGGTCAACA GAATGACTAT ATTCTTCTTT CTCTGGTACG AACCAGGGCA 
GTGGGCCATC TGAGGGATGT CCGTCGCTTG GTAGTGGCCA TGTCTAGAGC CAGACTTGGA 
CTTTATATCT TCGCCAGAGT ATCCCTCTTC CAAAACTGTT TTGAACTGAC TCCAGCTTTC 
AGTCAGCTCA CAGCTCGCCC CCTTCATTTG CATATAATTC CAACAGAACC TTTCCCAACT 
ACTAGAAAGA ATGGAGAGAG ACCATCTCAT GAAGTACAAA TAATAAAAAA TATGCCCCAG 
ATGGCAAACT TTGTATACAA CATGTACATG CATTTGATAC AGACTACACA TCATTATCAT 
CAGACTTTAT TACAACTACC ACCTGCTATG GTAGAAGAGG GTGAGGAAGT TCAAAATCAA 
GAAACAGAAT TGGAAACAGA AGAAGAGGCC ATGACTGTTC AAGCTGACAT CATACCCAGT 
CCAACAGACA CCAGCTGCCG TCAAGAAACT CCAGCCTTTC AAACTGACAC CACCCCCAGT 
GAGACAGGAG CCACTTCCAC TCCAGAAGCC ATCCCTGCTT TATCTGAGAC CACCCCTACT 
GTGGTAGGAG CTGTATCTGC ACCGGCAGAA GCTAACACAC CTCAGGATGC CACATCTGCC 
CCGGAAGAGA CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AQR ( NM_014691.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055506.1 Homo sapiens aquarius intron-binding spliceosomal factor (AQR), mRNA.

Price & Availability↑

CloneID	OHu06634
Clone ID Related Accession (Same CDS sequence)	NM_014691.2
Accession Version	NM_014691.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4458bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Homo sapiens(human)
Product	intron-binding protein aquarius
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL703893.1, AB011132.3 and BX647820.1. On Feb 1, 2005 this sequence version replaced NM_014691.1. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.158032.1, SRR1803615.107918.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGCAGCCC CTGCGCAGCC CAAGAAGATC GTGGCCCCTA CGGTGTCCCA AATCAATGCG 
GAGTTCGTGA CCCAGTTAGC ATGTAAATAC TGGGCTCCCC ACATCAAGAA GAAATCACCT 
TTTGATATAA AGGTTATTGA AGATATATAT GAAAAAGAGA TTGTCAAATC AAGGTTTGCT 
ATTAGAAAGA TAATGCTCTT GGAATTTAGC CAGTATCTTG AAAATTATCT CTGGATGAAT 
TATTCTCCTG AGGTATCTAG CAAGGCCTAT TTAATGTCAA TCTGCTGTAT GGTGAATGAG 
AAGTTTAGAG AAAACGTGCC TGCATGGGAG ATTTTTAAGA AGAAGCCAGA CCACTTCCCA 
TTCTTTTTTA AACACATCTT GAAGGCGGCA TTAGCTGAAA CTGATGGTGA ATTTTCACTT 
CATGAACAGA CAGTCTTACT ACTTTTTCTT GATCATTGCT TCAATAGTTT GGAAGTAGAC 
TTGATACGAA GTCAAGTACA GCAGCTTATC TCCCTCCCAA TGTGGATGGG CTTACAGCTG 
GCACGATTGG AATTAGAATT AAAAAAGACA CCTAAGCTAA GAAAATTCTG GAACTTGATT 
AAAAAGAATG ATGAAAAGAT GGATCCAGAA GCAAGAGAAC AGGCATATCA AGAGAGGAGA 
TTTCTTTCAC AACTCATCCA GAAGTTTATC TCTGTGCTGA AATCAGTCCC ACTTTCTGAA 
CCTGTCACTA TGGACAAAGT TCATTACTGT GAAAGATTCA TTGAACTTAT GATTGATCTA 
GAGGCCCTGC TACCCACAAG GCGCTGGTTT AATACCATCC TGGATGATTC CCACCTTCTG 
GTTCACTGTT ACCTTTCCAA TCTTGTTCGT AGAGAAGAGG ATGGCCATCT TTTTTCCCAG 
CTTTTGGACA TGCTTAAATT CTATACTGGT TTTGAAATTA ATGACCAAAC TGGAAATGCT 
CTGACAGAGA ATGAGATGAC CACAATTCAC TATGATAGAA TTACTTCTCT ACAGAGAGCT 
GCTTTTGCAC ATTTTCCTGA ACTCTATGAT TTTGCCCTCT CAAATGTGGC AGAAGTAGAT 
ACTCGGGAGT CCTTGGTCAA GTTTTTTGGA CCTCTTAGTT CAAACACACT CCACCAGGTG 
GCATCATACC TCTGCTTGTT GCCAACTCTT CCTAAAAATG AAGACACAAC TTTTGATAAA 
GAATTTCTTC TAGAATTGCT GGTATCTCGT CATGAACGTC GAATTTCTCA GATTCAGCAG 
TTGAACCAGA TGCCTTTGTA TCCAACTGAG AAAATTATAT GGGATGAAAA TATTGTCCCA 
ACTGAGTACT ATTCTGGAGA AGGTTGTCTT GCTCTTCCCA AATTGAATTT GCAGTTTTTG 
ACTCTTCATG ACTACCTGCT AAGGAACTTT AACCTCTTCC GCTTAGAATC AACTTATGAA 
ATTCGTCAGG ACATTGAAGA TAGTGTCAGC AGAATGAAGC CATGGCAATC TGAATATGGC 
GGTGTAGTGT TTGGTGGTTG GGCGCGAATG GCCCAGCCCA TTGTGGCTTT CACTGTCGTT 
GAAGTGGCCA AACCCAACAT AGGTGAAAAC TGGCCAACCC GAGTTCGTGC AGATGTTACC 
ATAAATCTCA ATGTCAGAGA TCACATCAAA GATGAATGGG AAGGTCTTCG TAAGCATGAT 
GTATGCTTTT TAATTACCGT ACGTCCCACA AAACCTTATG GCACTAAGTT TGACCGGAGG 
AGACCTTTTA TTGAGCAGGT TGGCCTGGTT TATGTCAGAG GCTGTGAAAT TCAGGGCATG 
CTGGATGATA AAGGACGTGT CATTGAAGAT GGACCTGAAC CCAGACCCAA TCTTAGAGGA 
GAATCAAGGA CATTTAGAGT GTTTTTGGAT CCAAACCAGT ATCAACAAGA TATGACCAAT 
ACTATACAAA ATGGAGCAGA GGATGTGTAT GAAACTTTTA ATATAATAAT GAGGAGAAAA 
CCAAAGGAAA ATAACTTTAA GGCTGTGCTG GAGACTATTC GGAACCTGAT GAATACTGAT 
TGTGTGGTAC CTGACTGGCT GCACGATATC ATTTTAGGTT ATGGGGACCC AAGTAGTGCA 
CATTATTCGA AAATGCCCAA TCAGATTGCC ACCCTTGATT TCAATGATAC ATTTCTCTCC 
ATTGAGCATT TAAAAGCCAG CTTCCCTGGT CATAATGTTA AAGTAACTGT AGAAGACCCT 
GCTCTACAAA TACCCCCTTT CAGGATAACT TTTCCAGTAA GAAGTGGAAA AGGGAAGAAA 
AGGAAAGATG CGGATGTGGA AGATGAAGAC ACCGAGGAAG CAAAAACCTT AATTGTTGAG 
CCCCATGTTA TTCCTAATAG GGGTCCTTAT CCTTATAATC AACCCAAACG TAATACGATT 
CAGTTCACTC ATACACAGAT AGAAGCCATC CGTGCTGGAA TGCAGCCTGG GCTGACTATG 
GTTGTGGGCC CACCTGGTAC AGGCAAAACA GATGTGGCAG TTCAGATCAT ATCCAACATC 
TACCACAACT TCCCAGAACA GAGGACTCTA ATTGTTACTC ATTCCAATCA GGCCCTAAAC 
CAGTTGTTTG AGAAAATCAT GGCATTAGAC ATTGATGAGC GCCACCTACT GCGTCTTGGT 
CATGGAGAAG AAGAGCTGGA GACAGAGAAA GATTTCAGCA GGTATGGAAG AGTTAATTAT 
GTTCTGGCTC GAAGAATAGA ACTTTTAGAA GAAGTCAAAC GATTGCAAAA GAGTCTAGGG 
GTTCCAGGAG ATGCCTCATA TACCTGTGAA ACTGCAGGCT ATTTCTTCTT ATACCAGGTA 
ATGTCTCGCT GGGAAGAGTA TATCAGCAAA GTGAAAAATA AAGGTAGTAC ATTGCCAGAT 
GTTACGGAAG TCTCCACTTT CTTCCCTTTC CATGAATACT TTGCAAATGC TCCTCAACCC 
ATTTTTAAAG GAAGATCTTA TGAAGAAGAC ATGGAAATTG CTGAAGGATG TTTCAGGCAT 
ATTAAGAAAA TCTTTACGCA GCTTGAGGAA TTCAGAGCCT CTGAATTGCT TCGAAGTGGA 
CTGGACAGAT CTAAATACCT TTTAGTGAAA GAAGCCAAAA TTATTGCTAT GACCTGTACT 
CATGCTGCCT TAAAACGACA TGACTTGGTC AAGCTAGGTT TCAAGTATGA CAACATTTTG 
ATGGAAGAGG CTGCTCAGAT TCTGGAGATA GAAACTTTTA TCCCTCTTCT TCTACAGAAT 
CCTCAGGATG GATTTAGCCG ACTAAAACGA TGGATTATGA TTGGCGATCA TCACCAGTTA 
CCTCCAGTTA TTAAGAACAT GGCCTTTCAA AAGTACTCAA ACATGGAGCA GTCTCTCTTC 
ACTCGCTTTG TTCGCGTTGG AGTTCCGACT GTTGACCTTG ATGCTCAAGG GAGAGCCAGA 
GCAAGCTTGT GCAACCTCTA CAACTGGCGA TACAAGAATC TAGGAAACTT ACCCCATGTG 
CAGCTCTTGC CAGAGTTTAG TACAGCAAAT GCTGGCTTAC TGTATGACTT CCAGCTCATT 
AATGTTGAAG ATTTTCAAGG AGTGGGAGAA TCTGAACCTA ATCCTTACTT CTATCAGAAT 
CTTGGAGAGG CAGAATATGT AGTAGCACTT TTTATGTACA TGTGTTTACT TGGTTACCCT 
GCTGACAAAA TCAGTATTCT AACAACATAT AATGGCCAAA AGCATCTTAT TCGCGACATC 
ATCAATAGAC GATGTGGAAA CAATCCATTG ATTGGAAGAC CAAACAAGGT GACAACTGTT 
GATAGATTTC AAGGTCAACA GAATGACTAT ATTCTTCTTT CTCTGGTACG AACCAGGGCA 
GTGGGCCATC TGAGGGATGT CCGTCGCTTG GTAGTGGCCA TGTCTAGAGC CAGACTTGGA 
CTTTATATCT TCGCCAGAGT ATCCCTCTTC CAAAACTGTT TTGAACTGAC TCCAGCTTTC 
AGTCAGCTCA CAGCTCGCCC CCTTCATTTG CATATAATTC CAACAGAACC TTTCCCAACT 
ACTAGAAAGA ATGGAGAGAG ACCATCTCAT GAAGTACAAA TAATAAAAAA TATGCCCCAG 
ATGGCAAACT TTGTATACAA CATGTACATG CATTTGATAC AGACTACACA TCATTATCAT 
CAGACTTTAT TACAACTACC ACCTGCTATG GTAGAAGAGG GTGAGGAAGT TCAAAATCAA 
GAAACAGAAT TGGAAACAGA AGAAGAGGCC ATGACTGTTC AAGCTGACAT CATACCCAGT 
CCAACAGACA CCAGCTGCCG TCAAGAAACT CCAGCCTTTC AAACTGACAC CACCCCCAGT 
GAGACAGGAG CCACTTCCAC TCCAGAAGCC ATCCCTGCTT TATCTGAGAC CACCCCTACT 
GTGGTAGGAG CTGTATCTGC ACCGGCAGAA GCTAACACAC CTCAGGATGC CACATCTGCC 
CCAGAAGAGA CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055506.1
CDS	182..4639
Translation	MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKVIEDIYEKEIVKSRFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPDHFPFFFKHILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADIIPSPTDTSCRQETPAFQTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK

Target ORF information:

RefSeq Version	NM_014691.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aquarius intron-binding spliceosomal factor (AQR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014691.2

ORF Insert Sequence:

ATGGCAGCCC CTGCGCAGCC CAAGAAGATC GTGGCCCCTA CGGTGTCCCA AATCAATGCG 
GAGTTCGTGA CCCAGTTAGC ATGTAAATAC TGGGCTCCCC ACATCAAGAA GAAATCACCT 
TTTGATATAA AGGTTATTGA AGATATATAT GAAAAAGAGA TTGTCAAATC AAGGTTTGCT 
ATTAGAAAGA TAATGCTCTT GGAATTTAGC CAGTATCTTG AAAATTATCT CTGGATGAAT 
TATTCTCCTG AGGTATCTAG CAAGGCCTAT TTAATGTCAA TCTGCTGTAT GGTGAATGAG 
AAGTTTAGAG AAAACGTGCC TGCATGGGAG ATTTTTAAGA AGAAGCCAGA CCACTTCCCA 
TTCTTTTTTA AACACATCTT GAAGGCGGCA TTAGCTGAAA CTGATGGTGA ATTTTCACTT 
CATGAACAGA CAGTCTTACT ACTTTTTCTT GATCATTGCT TCAATAGTTT GGAAGTAGAC 
TTGATACGAA GTCAAGTACA GCAGCTTATC TCCCTCCCAA TGTGGATGGG CTTACAGCTG 
GCACGATTGG AATTAGAATT AAAAAAGACA CCTAAGCTAA GAAAATTCTG GAACTTGATT 
AAAAAGAATG ATGAAAAGAT GGATCCAGAA GCAAGAGAAC AGGCATATCA AGAGAGGAGA 
TTTCTTTCAC AACTCATCCA GAAGTTTATC TCTGTGCTGA AATCAGTCCC ACTTTCTGAA 
CCTGTCACTA TGGACAAAGT TCATTACTGT GAAAGATTCA TTGAACTTAT GATTGATCTA 
GAGGCCCTGC TACCCACAAG GCGCTGGTTT AATACCATCC TGGATGATTC CCACCTTCTG 
GTTCACTGTT ACCTTTCCAA TCTTGTTCGT AGAGAAGAGG ATGGCCATCT TTTTTCCCAG 
CTTTTGGACA TGCTTAAATT CTATACTGGT TTTGAAATTA ATGACCAAAC TGGAAATGCT 
CTGACAGAGA ATGAGATGAC CACAATTCAC TATGATAGAA TTACTTCTCT ACAGAGAGCT 
GCTTTTGCAC ATTTTCCTGA ACTCTATGAT TTTGCCCTCT CAAATGTGGC AGAAGTAGAT 
ACTCGGGAGT CCTTGGTCAA GTTTTTTGGA CCTCTTAGTT CAAACACACT CCACCAGGTG 
GCATCATACC TCTGCTTGTT GCCAACTCTT CCTAAAAATG AAGACACAAC TTTTGATAAA 
GAATTTCTTC TAGAATTGCT GGTATCTCGT CATGAACGTC GAATTTCTCA GATTCAGCAG 
TTGAACCAGA TGCCTTTGTA TCCAACTGAG AAAATTATAT GGGATGAAAA TATTGTCCCA 
ACTGAGTACT ATTCTGGAGA AGGTTGTCTT GCTCTTCCCA AATTGAATTT GCAGTTTTTG 
ACTCTTCATG ACTACCTGCT AAGGAACTTT AACCTCTTCC GCTTAGAATC AACTTATGAA 
ATTCGTCAGG ACATTGAAGA TAGTGTCAGC AGAATGAAGC CATGGCAATC TGAATATGGC 
GGTGTAGTGT TTGGTGGTTG GGCGCGAATG GCCCAGCCCA TTGTGGCTTT CACTGTCGTT 
GAAGTGGCCA AACCCAACAT AGGTGAAAAC TGGCCAACCC GAGTTCGTGC AGATGTTACC 
ATAAATCTCA ATGTCAGAGA TCACATCAAA GATGAATGGG AAGGTCTTCG TAAGCATGAT 
GTATGCTTTT TAATTACCGT ACGTCCCACA AAACCTTATG GCACTAAGTT TGACCGGAGG 
AGACCTTTTA TTGAGCAGGT TGGCCTGGTT TATGTCAGAG GCTGTGAAAT TCAGGGCATG 
CTGGATGATA AAGGACGTGT CATTGAAGAT GGACCTGAAC CCAGACCCAA TCTTAGAGGA 
GAATCAAGGA CATTTAGAGT GTTTTTGGAT CCAAACCAGT ATCAACAAGA TATGACCAAT 
ACTATACAAA ATGGAGCAGA GGATGTGTAT GAAACTTTTA ATATAATAAT GAGGAGAAAA 
CCAAAGGAAA ATAACTTTAA GGCTGTGCTG GAGACTATTC GGAACCTGAT GAATACTGAT 
TGTGTGGTAC CTGACTGGCT GCACGATATC ATTTTAGGTT ATGGGGACCC AAGTAGTGCA 
CATTATTCGA AAATGCCCAA TCAGATTGCC ACCCTTGATT TCAATGATAC ATTTCTCTCC 
ATTGAGCATT TAAAAGCCAG CTTCCCTGGT CATAATGTTA AAGTAACTGT AGAAGACCCT 
GCTCTACAAA TACCCCCTTT CAGGATAACT TTTCCAGTAA GAAGTGGAAA AGGGAAGAAA 
AGGAAAGATG CGGATGTGGA AGATGAAGAC ACCGAGGAAG CAAAAACCTT AATTGTTGAG 
CCCCATGTTA TTCCTAATAG GGGTCCTTAT CCTTATAATC AACCCAAACG TAATACGATT 
CAGTTCACTC ATACACAGAT AGAAGCCATC CGTGCTGGAA TGCAGCCTGG GCTGACTATG 
GTTGTGGGCC CACCTGGTAC AGGCAAAACA GATGTGGCAG TTCAGATCAT ATCCAACATC 
TACCACAACT TCCCAGAACA GAGGACTCTA ATTGTTACTC ATTCCAATCA GGCCCTAAAC 
CAGTTGTTTG AGAAAATCAT GGCATTAGAC ATTGATGAGC GCCACCTACT GCGTCTTGGT 
CATGGAGAAG AAGAGCTGGA GACAGAGAAA GATTTCAGCA GGTATGGAAG AGTTAATTAT 
GTTCTGGCTC GAAGAATAGA ACTTTTAGAA GAAGTCAAAC GATTGCAAAA GAGTCTAGGG 
GTTCCAGGAG ATGCCTCATA TACCTGTGAA ACTGCAGGCT ATTTCTTCTT ATACCAGGTA 
ATGTCTCGCT GGGAAGAGTA TATCAGCAAA GTGAAAAATA AAGGTAGTAC ATTGCCAGAT 
GTTACGGAAG TCTCCACTTT CTTCCCTTTC CATGAATACT TTGCAAATGC TCCTCAACCC 
ATTTTTAAAG GAAGATCTTA TGAAGAAGAC ATGGAAATTG CTGAAGGATG TTTCAGGCAT 
ATTAAGAAAA TCTTTACGCA GCTTGAGGAA TTCAGAGCCT CTGAATTGCT TCGAAGTGGA 
CTGGACAGAT CTAAATACCT TTTAGTGAAA GAAGCCAAAA TTATTGCTAT GACCTGTACT 
CATGCTGCCT TAAAACGACA TGACTTGGTC AAGCTAGGTT TCAAGTATGA CAACATTTTG 
ATGGAAGAGG CTGCTCAGAT TCTGGAGATA GAAACTTTTA TCCCTCTTCT TCTACAGAAT 
CCTCAGGATG GATTTAGCCG ACTAAAACGA TGGATTATGA TTGGCGATCA TCACCAGTTA 
CCTCCAGTTA TTAAGAACAT GGCCTTTCAA AAGTACTCAA ACATGGAGCA GTCTCTCTTC 
ACTCGCTTTG TTCGCGTTGG AGTTCCGACT GTTGACCTTG ATGCTCAAGG GAGAGCCAGA 
GCAAGCTTGT GCAACCTCTA CAACTGGCGA TACAAGAATC TAGGAAACTT ACCCCATGTG 
CAGCTCTTGC CAGAGTTTAG TACAGCAAAT GCTGGCTTAC TGTATGACTT CCAGCTCATT 
AATGTTGAAG ATTTTCAAGG AGTGGGAGAA TCTGAACCTA ATCCTTACTT CTATCAGAAT 
CTTGGAGAGG CAGAATATGT AGTAGCACTT TTTATGTACA TGTGTTTACT TGGTTACCCT 
GCTGACAAAA TCAGTATTCT AACAACATAT AATGGCCAAA AGCATCTTAT TCGCGACATC 
ATCAATAGAC GATGTGGAAA CAATCCATTG ATTGGAAGAC CAAACAAGGT GACAACTGTT 
GATAGATTTC AAGGTCAACA GAATGACTAT ATTCTTCTTT CTCTGGTACG AACCAGGGCA 
GTGGGCCATC TGAGGGATGT CCGTCGCTTG GTAGTGGCCA TGTCTAGAGC CAGACTTGGA 
CTTTATATCT TCGCCAGAGT ATCCCTCTTC CAAAACTGTT TTGAACTGAC TCCAGCTTTC 
AGTCAGCTCA CAGCTCGCCC CCTTCATTTG CATATAATTC CAACAGAACC TTTCCCAACT 
ACTAGAAAGA ATGGAGAGAG ACCATCTCAT GAAGTACAAA TAATAAAAAA TATGCCCCAG 
ATGGCAAACT TTGTATACAA CATGTACATG CATTTGATAC AGACTACACA TCATTATCAT 
CAGACTTTAT TACAACTACC ACCTGCTATG GTAGAAGAGG GTGAGGAAGT TCAAAATCAA 
GAAACAGAAT TGGAAACAGA AGAAGAGGCC ATGACTGTTC AAGCTGACAT CATACCCAGT 
CCAACAGACA CCAGCTGCCG TCAAGAAACT CCAGCCTTTC AAACTGACAC CACCCCCAGT 
GAGACAGGAG CCACTTCCAC TCCAGAAGCC ATCCCTGCTT TATCTGAGAC CACCCCTACT 
GTGGTAGGAG CTGTATCTGC ACCGGCAGAA GCTAACACAC CTCAGGATGC CACATCTGCC 
CCAGAAGAGA CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

AQR is a novel type 2 diabetes-associated gene that regulates signaling pathways critical for glucose metabolism.
Journal of genetics and genomics = Yi chuan xue bao45(2)111-120(2018 02)
Song C,Yan H,Wang H,Zhang Y,Cao H,Wan Y,Kong L,Chen S,Xu H,Pan B,Zhang J,Fan G,Xin H,Liang Z,Jia W,Tian XL

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature542(7641)318-323(2017 02)
Bertram K,Agafonov DE,Liu WT,Dybkov O,Will CL,Hartmuth K,Urlaub H,Kastner B,Stark H,Lührmann R

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes.
Nature structural & molecular biology22(2)138-44(2015 Feb)
De I,Bessonov S,Hofele R,dos Santos K,Will CL,Urlaub H,Lührmann R,Pena V

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

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AQR cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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