TTYH2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TTYH2
Entrez Gene ID	94015
Full Name	tweety family member 2
Synonyms	C17orf29
General protein information	Preferred Names tweety family member 2 Names protein tweety homolog 2 hTTY2 tweety homolog 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.1
Summary	This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	608855

mRNA and Protein(s)

mRNA	Protein	Name
NM_032646.6	NP_116035.5	protein tweety homolog 2 isoform 1
NM_001330453.1	NP_001317382.1	protein tweety homolog 2 isoform 3
NM_001330453.2	NP_001317382.1	protein tweety homolog 2 isoform 3
NM_032646.5	NP_116035.5	protein tweety homolog 2 isoform 1
NM_052869.1	NP_443101.1	protein tweety homolog 2 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TTYH2	NP_001099096.1
Homo sapiens (human)	TTYH2	NP_116035.5
Canis lupus familiaris (dog)	TTYH2	XP_005624201.1
Xenopus tropicalis (tropical clawed frog)	ttyh2	NP_989411.1
Pan troglodytes (chimpanzee)	TTYH2	XP_001168124.1
Mus musculus (house mouse)	Ttyh2	NP_444503.2
Rattus norvegicus (Norway rat)	Ttyh2	XP_221081.7
Danio rerio (zebrafish)	ttyh2l	NP_998421.1
Gallus gallus (chicken)	TTYH2	XP_003642401.2

Gene Ontology
Bibliography

Related articles in PubMed

The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.
He Y, Hryciw DH, Carroll ML, Myers SA, Whitbread AK, Kumar S, Poronnik P, Hooper JD
The Journal of biological chemistry283(35)24000-10(2008 Aug)

N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).
He Y, Ramsay AJ, Hunt ML, Whitbread AK, Myers SA, Hooper JD
The Biochemical journal412(1)45-55(2008 May)

TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is up-regulated in colon carcinoma and involved in cell proliferation and cell aggregation.
Toiyama Y, Mizoguchi A, Kimura K, Hiro J, Inoue Y, Tutumi T, Miki C, Kusunoki M
World journal of gastroenterology13(19)2717-21(2007 May)

A novel human Cl(-) channel family related to Drosophila flightless locus.
Suzuki M, Mizuno A
The Journal of biological chemistry279(21)22461-8(2004 May)

A novel proteomic approach for specific identification of tyrosine kinase substrates using [13C]tyrosine.
Ibarrola N, Molina H, Iwahori A, Pandey A
The Journal of biological chemistry279(16)15805-13(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TTYH2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TTYH2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu50816	NM_001330453.2 Latest version!	Homo sapiens tweety family member 2 (TTYH2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu29362	NM_052869.1 Latest version!	Homo sapiens tweety family member 2 (TTYH2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
OHu29367	NM_032646.6 Latest version!	Homo sapiens tweety family member 2 (TTYH2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
View Old Accession Versions >>
OHu50816	NM_001330453.1	Homo sapiens tweety family member 2 (TTYH2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu29367	NM_032646.5	Homo sapiens tweety family member 2 (TTYH2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TTYH2 ( NM_001330453.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317382.1 Homo sapiens tweety family member 2 (TTYH2), transcript variant 3, mRNA.

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CloneID	OHu50816
Clone ID Related Accession (Same CDS sequence)	NM_001330453.1 , NM_001330453.2
Accession Version	NM_001330453.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530288000000
Organism	Homo sapiens(human)
Product	protein tweety homolog 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM548398.1, AK296511.1 and BC004233.2. On Aug 29, 2016 this sequence version replaced XM_005257824.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.244673.1, SRR1803617.232258.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGTGG TGGGCCAGGA CCGGAAGTCT GGCTCTGGGT GTTATTTAAG GTGGCTCCTG 
TTTTTGTCGC TGCTGTTCCT GGGGCTGGTG GCCGCCGTCT GCCTGGGCCT GAACCTCATC 
TTCCTTGTGG CTTACCTGGT CTGTGCATGC CACTGCCGGC GGGACGATGC GGTGCAGACC 
AAGCAGCACC ACTCCTGCTG CATCACCTGG ACGGCCGTGG TGGCCGGGCT CATCTGCTGT 
GCTGCGGTGG GCGTTGGTTT CTATGGAAAC AGCGAGACCA ACGATGGGGC GTACCAGCTG 
ATGTACTCCT TGGACGATGC CAACCACACC TTCTCTGGGA TCGATGCTCT GGTTTCCGGA 
ACTACCCAGA AGATGAAGGT GGACCTAGAG CAGCACCTGG CCCGGCTCAG TGAGATCTTT 
GCTGCCCGGG GCGATTACCT GCAGACCCTG AAGTTCATAC AGCAGATGGC GGGCAGCGTT 
GTTGTTCAGC TCTCAGGACT GCCCGTGTGG AGGGAGGTCA CCATGGAGCT GACCAAGCTA 
TCCGACCAGA CTGGCTACGT GGAGTACTAC AGGTGGCTCT CCTACCTCCT GCTCTTTATC 
CTGGACCTGG TCATCTGCCT CATTGCCTGC CTGGGACTGG CCAAGCGCTC CAAGTGTCTC 
CTGGCCTCGA TGCTGTGCTG TGGGGCACTG AGCCTGCTCC TCAGTTGGGC ATCCCTGGCC 
GCTGATGGCT CTGCGGCAGT GGCCACCAGT GACTTCTGTG TGGCTCCTGA CACCTTCATC 
CTGAACGTCA CGGAGGGCCA GATCAGCACA GAGGTGACTC GCTACTACCT GTATTGCAGC 
CAGAGTGGAA GCAGCCCCTT CCAGCAGACC CTGACCACCT TCCAGCGCGC ACTTACCACC 
ATGCAGATCC AGGTCGCGGG GCTGCTGCAG TTTGCCGTGC CCCTCTTCTC CACTGCAGAG 
GAAGACCTGC TTGCAATCCA GCTCCTGCTG AACTCCTCAG AGTCCAGCCT TCACCAGCTG 
ACCGCCATGG TGGACTGCCG AGGGCTGCAC AAGGATTATC TGGACGCTCT TGCTGGCATC 
TGCTACGACG GCCTCCAGGG CTTGCTGTAC CTTGGCCTCT TCTCCTTCCT GGCCGCCCTC 
GCCTTCTCCA CCATGATCTG TGCAGGGCCA AGGGCCTGGA AGCACTTCAC CACCAGAAAC 
AGAGACTACG ATGACATTGA TGATGATGAC CCCTTTAACC CCCAAGCCTG GCGCATGGCG 
GCTCACAGTC CCCCGAGGGG ACAGCTTCAC AGCTTCTGCA GCTACAGCAG TGGCCTGGGA 
AGTCAGACCA GCCTGCAGCC CCCGGCCCAG ACCATCTCCA ACGCCCCTGT CTCCGAGTAC 
ATGAACCAAG CCATGCTCTT TGGTAGGAAC CCACGCTACG AGAACGTGCC ACTAATCGGG 
AGAGCCTCCC CTCCGCCTAC GTACTCTCCC AGCATGAGAG CCACCTACCT GTCTGTGGCG 
GATGAGCACC TGAGGCACTA CGGGAATCAG TTTCCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317382.1
CDS	32..1573
Translation	MSVVGQDRKSGSGCYLRWLLFLSLLFLGLVAAVCLGLNLIFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQLMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGSVVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKCLLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYCSQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA

Target ORF information:

RefSeq Version	NM_001330453.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 2 (TTYH2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330453.1

ORF Insert Sequence:

ATGAGCGTGG TGGGCCAGGA CCGGAAGTCT GGCTCTGGGT GTTATTTAAG GTGGCTCCTG 
TTTTTGTCGC TGCTGTTCCT GGGGCTGGTG GCCGCCGTCT GCCTGGGCCT GAACCTCATC 
TTCCTTGTGG CTTACCTGGT CTGTGCATGC CACTGCCGGC GGGACGATGC GGTGCAGACC 
AAGCAGCACC ACTCCTGCTG CATCACCTGG ACGGCCGTGG TGGCCGGGCT CATCTGCTGT 
GCTGCGGTGG GCGTTGGTTT CTATGGAAAC AGCGAGACCA ACGATGGGGC GTACCAGCTG 
ATGTACTCCT TGGACGATGC CAACCACACC TTCTCTGGGA TCGATGCTCT GGTTTCCGGA 
ACTACCCAGA AGATGAAGGT GGACCTAGAG CAGCACCTGG CCCGGCTCAG TGAGATCTTT 
GCTGCCCGGG GCGATTACCT GCAGACCCTG AAGTTCATAC AGCAGATGGC GGGCAGCGTT 
GTTGTTCAGC TCTCAGGACT GCCCGTGTGG AGGGAGGTCA CCATGGAGCT GACCAAGCTA 
TCCGACCAGA CTGGCTACGT GGAGTACTAC AGGTGGCTCT CCTACCTCCT GCTCTTTATC 
CTGGACCTGG TCATCTGCCT CATTGCCTGC CTGGGACTGG CCAAGCGCTC CAAGTGTCTC 
CTGGCCTCGA TGCTGTGCTG TGGGGCACTG AGCCTGCTCC TCAGTTGGGC ATCCCTGGCC 
GCTGATGGCT CTGCGGCAGT GGCCACCAGT GACTTCTGTG TGGCTCCTGA CACCTTCATC 
CTGAACGTCA CGGAGGGCCA GATCAGCACA GAGGTGACTC GCTACTACCT GTATTGCAGC 
CAGAGTGGAA GCAGCCCCTT CCAGCAGACC CTGACCACCT TCCAGCGCGC ACTTACCACC 
ATGCAGATCC AGGTCGCGGG GCTGCTGCAG TTTGCCGTGC CCCTCTTCTC CACTGCAGAG 
GAAGACCTGC TTGCAATCCA GCTCCTGCTG AACTCCTCAG AGTCCAGCCT TCACCAGCTG 
ACCGCCATGG TGGACTGCCG AGGGCTGCAC AAGGATTATC TGGACGCTCT TGCTGGCATC 
TGCTACGACG GCCTCCAGGG CTTGCTGTAC CTTGGCCTCT TCTCCTTCCT GGCCGCCCTC 
GCCTTCTCCA CCATGATCTG TGCAGGGCCA AGGGCCTGGA AGCACTTCAC CACCAGAAAC 
AGAGACTACG ATGACATTGA TGATGATGAC CCCTTTAACC CCCAAGCCTG GCGCATGGCG 
GCTCACAGTC CCCCGAGGGG ACAGCTTCAC AGCTTCTGCA GCTACAGCAG TGGCCTGGGA 
AGTCAGACCA GCCTGCAGCC CCCGGCCCAG ACCATCTCCA ACGCCCCTGT CTCCGAGTAC 
ATGAACCAAG CCATGCTCTT TGGTAGGAAC CCACGCTACG AGAACGTGCC ACTAATCGGG 
AGAGCCTCCC CTCCGCCTAC GTACTCTCCC AGCATGAGAG CCACCTACCT GTCTGTGGCG 
GATGAGCACC TGAGGCACTA CGGGAATCAG TTTCCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH2 ( NM_001330453.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317382.1 Homo sapiens tweety family member 2 (TTYH2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu50816
Clone ID Related Accession (Same CDS sequence)	NM_001330453.1 , NM_001330453.2
Accession Version	NM_001330453.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559145600000
Organism	Homo sapiens(human)
Product	protein tweety homolog 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM548398.1, AK296511.1 and BC004233.2. On May 31, 2019 this sequence version replaced NM_001330453.1. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.140033.1, SRR1803615.228617.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGTGG TGGGCCAGGA CCGGAAGTCT GGCTCTGGGT GTTATTTAAG GTGGCTCCTG 
TTTTTGTCGC TGCTGTTCCT GGGGCTGGTG GCCGCCGTCT GCCTGGGCCT GAACCTCATC 
TTCCTTGTGG CTTACCTGGT CTGTGCATGC CACTGCCGGC GGGACGATGC GGTGCAGACC 
AAGCAGCACC ACTCCTGCTG CATCACCTGG ACGGCCGTGG TGGCCGGGCT CATCTGCTGT 
GCTGCGGTGG GCGTTGGTTT CTATGGAAAC AGCGAGACCA ACGATGGGGC GTACCAGCTG 
ATGTACTCCT TGGACGATGC CAACCACACC TTCTCTGGGA TCGATGCTCT GGTTTCCGGA 
ACTACCCAGA AGATGAAGGT GGACCTAGAG CAGCACCTGG CCCGGCTCAG TGAGATCTTT 
GCTGCCCGGG GCGATTACCT GCAGACCCTG AAGTTCATAC AGCAGATGGC GGGCAGCGTT 
GTTGTTCAGC TCTCAGGACT GCCCGTGTGG AGGGAGGTCA CCATGGAGCT GACCAAGCTA 
TCCGACCAGA CTGGCTACGT GGAGTACTAC AGGTGGCTCT CCTACCTCCT GCTCTTTATC 
CTGGACCTGG TCATCTGCCT CATTGCCTGC CTGGGACTGG CCAAGCGCTC CAAGTGTCTC 
CTGGCCTCGA TGCTGTGCTG TGGGGCACTG AGCCTGCTCC TCAGTTGGGC ATCCCTGGCC 
GCTGATGGCT CTGCGGCAGT GGCCACCAGT GACTTCTGTG TGGCTCCTGA CACCTTCATC 
CTGAACGTCA CGGAGGGCCA GATCAGCACA GAGGTGACTC GCTACTACCT GTATTGCAGC 
CAGAGTGGAA GCAGCCCCTT CCAGCAGACC CTGACCACCT TCCAGCGCGC ACTTACCACC 
ATGCAGATCC AGGTCGCGGG GCTGCTGCAG TTTGCCGTGC CCCTCTTCTC CACTGCAGAG 
GAAGACCTGC TTGCAATCCA GCTCCTGCTG AACTCCTCAG AGTCCAGCCT TCACCAGCTG 
ACCGCCATGG TGGACTGCCG AGGGCTGCAC AAGGATTATC TGGACGCTCT TGCTGGCATC 
TGCTACGACG GCCTCCAGGG CTTGCTGTAC CTTGGCCTCT TCTCCTTCCT GGCCGCCCTC 
GCCTTCTCCA CCATGATCTG TGCAGGGCCA AGGGCCTGGA AGCACTTCAC CACCAGAAAC 
AGAGACTACG ATGACATTGA TGATGATGAC CCCTTTAACC CCCAAGCCTG GCGCATGGCG 
GCTCACAGTC CCCCGAGGGG ACAGCTTCAC AGCTTCTGCA GCTACAGCAG TGGCCTGGGA 
AGTCAGACCA GCCTGCAGCC CCCGGCCCAG ACCATCTCCA ACGCCCCTGT CTCCGAGTAC 
ATGAACCAAG CCATGCTCTT TGGTAGGAAC CCACGCTACG AGAACGTGCC ACTAATCGGG 
AGAGCCTCCC CTCCGCCTAC GTACTCTCCC AGCATGAGAG CCACCTACCT GTCTGTGGCG 
GATGAGCACC TGAGGCACTA CGGGAATCAG TTTCCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317382.1
CDS	18..1559
Translation	MSVVGQDRKSGSGCYLRWLLFLSLLFLGLVAAVCLGLNLIFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQLMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGSVVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKCLLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYCSQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA

Target ORF information:

RefSeq Version	NM_001330453.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 2 (TTYH2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330453.2

ORF Insert Sequence:

ATGAGCGTGG TGGGCCAGGA CCGGAAGTCT GGCTCTGGGT GTTATTTAAG GTGGCTCCTG 
TTTTTGTCGC TGCTGTTCCT GGGGCTGGTG GCCGCCGTCT GCCTGGGCCT GAACCTCATC 
TTCCTTGTGG CTTACCTGGT CTGTGCATGC CACTGCCGGC GGGACGATGC GGTGCAGACC 
AAGCAGCACC ACTCCTGCTG CATCACCTGG ACGGCCGTGG TGGCCGGGCT CATCTGCTGT 
GCTGCGGTGG GCGTTGGTTT CTATGGAAAC AGCGAGACCA ACGATGGGGC GTACCAGCTG 
ATGTACTCCT TGGACGATGC CAACCACACC TTCTCTGGGA TCGATGCTCT GGTTTCCGGA 
ACTACCCAGA AGATGAAGGT GGACCTAGAG CAGCACCTGG CCCGGCTCAG TGAGATCTTT 
GCTGCCCGGG GCGATTACCT GCAGACCCTG AAGTTCATAC AGCAGATGGC GGGCAGCGTT 
GTTGTTCAGC TCTCAGGACT GCCCGTGTGG AGGGAGGTCA CCATGGAGCT GACCAAGCTA 
TCCGACCAGA CTGGCTACGT GGAGTACTAC AGGTGGCTCT CCTACCTCCT GCTCTTTATC 
CTGGACCTGG TCATCTGCCT CATTGCCTGC CTGGGACTGG CCAAGCGCTC CAAGTGTCTC 
CTGGCCTCGA TGCTGTGCTG TGGGGCACTG AGCCTGCTCC TCAGTTGGGC ATCCCTGGCC 
GCTGATGGCT CTGCGGCAGT GGCCACCAGT GACTTCTGTG TGGCTCCTGA CACCTTCATC 
CTGAACGTCA CGGAGGGCCA GATCAGCACA GAGGTGACTC GCTACTACCT GTATTGCAGC 
CAGAGTGGAA GCAGCCCCTT CCAGCAGACC CTGACCACCT TCCAGCGCGC ACTTACCACC 
ATGCAGATCC AGGTCGCGGG GCTGCTGCAG TTTGCCGTGC CCCTCTTCTC CACTGCAGAG 
GAAGACCTGC TTGCAATCCA GCTCCTGCTG AACTCCTCAG AGTCCAGCCT TCACCAGCTG 
ACCGCCATGG TGGACTGCCG AGGGCTGCAC AAGGATTATC TGGACGCTCT TGCTGGCATC 
TGCTACGACG GCCTCCAGGG CTTGCTGTAC CTTGGCCTCT TCTCCTTCCT GGCCGCCCTC 
GCCTTCTCCA CCATGATCTG TGCAGGGCCA AGGGCCTGGA AGCACTTCAC CACCAGAAAC 
AGAGACTACG ATGACATTGA TGATGATGAC CCCTTTAACC CCCAAGCCTG GCGCATGGCG 
GCTCACAGTC CCCCGAGGGG ACAGCTTCAC AGCTTCTGCA GCTACAGCAG TGGCCTGGGA 
AGTCAGACCA GCCTGCAGCC CCCGGCCCAG ACCATCTCCA ACGCCCCTGT CTCCGAGTAC 
ATGAACCAAG CCATGCTCTT TGGTAGGAAC CCACGCTACG AGAACGTGCC ACTAATCGGG 
AGAGCCTCCC CTCCGCCTAC GTACTCTCCC AGCATGAGAG CCACCTACCT GTCTGTGGCG 
GATGAGCACC TGAGGCACTA CGGGAATCAG TTTCCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH2 ( NM_052869.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_443101.1 Homo sapiens tweety family member 2 (TTYH2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29362
Clone ID Related Accession (Same CDS sequence)	NM_052869.1
Accession Version	NM_052869.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564675200000
Organism	Homo sapiens(human)
Product	protein tweety homolog 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX647912.1, AK126955.1, BC005168.1, AF319952.1, AK091085.1 and BC004233.2. Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (2) contains a shorter C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BX647912.1, AK126955.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGATCC AGGTCGCGGG GCTGCTGCAG TTTGCCGTGC CCCTCTTCTC CACTGCAGAG 
GAAGACCTGC TTGCAATCCA GCTCCTGCTG AACTCCTCAG AGTCCAGCCT TCACCAGCTG 
ACCGCCATGG TGGACTGCCG AGGGCTGCAC AAGGATTATC TGGACGCTCT TGCTGGCATC 
TGCTACGACG GCCTCCAGGG CTTGCTGTAC CTTGGCCTCT TCTCCTTCCT GGCCGCCCTC 
GCCTTCTCCA CCATGATCTG TGCAGGGCCA AGGGCCTGGA AGCACTTCAC CACCAGAAAC 
AGAGACTACG ATGACATTGA TGATGATGAC CCCTTTAACC CCCAAGCCTG GCGCATGGCG 
GCTCACAGTC CCCCGAGGGG ACAGCTTCAC AGCTTCTGCA GCTACAGCAG TGGCCTGGGA 
AGTCAGACCA GCCTGCAGCC CCCGGCCCAG ACCATCTCCA ACGCCCCTGT CTCCGAGTAC 
ATGAACCAAG CCATGCTCTT TGGTAGGAAC CCACGCTACG AGAACGTGCC ACTAATCGGG 
AGAGCCTCCC CTCCGCCTAC GTACTCTCCC AGCATGAGAG CCACCTACCT GTCTGTGGCG 
GATGAGCACC TGAGGCACTA CGGGAATCAG TTTCCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_443101.1
CDS	805..1446
Translation	MQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA

Target ORF information:

RefSeq Version	NM_052869.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 2 (TTYH2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_052869.1

ORF Insert Sequence:

ATGCAGATCC AGGTCGCGGG GCTGCTGCAG TTTGCCGTGC CCCTCTTCTC CACTGCAGAG 
GAAGACCTGC TTGCAATCCA GCTCCTGCTG AACTCCTCAG AGTCCAGCCT TCACCAGCTG 
ACCGCCATGG TGGACTGCCG AGGGCTGCAC AAGGATTATC TGGACGCTCT TGCTGGCATC 
TGCTACGACG GCCTCCAGGG CTTGCTGTAC CTTGGCCTCT TCTCCTTCCT GGCCGCCCTC 
GCCTTCTCCA CCATGATCTG TGCAGGGCCA AGGGCCTGGA AGCACTTCAC CACCAGAAAC 
AGAGACTACG ATGACATTGA TGATGATGAC CCCTTTAACC CCCAAGCCTG GCGCATGGCG 
GCTCACAGTC CCCCGAGGGG ACAGCTTCAC AGCTTCTGCA GCTACAGCAG TGGCCTGGGA 
AGTCAGACCA GCCTGCAGCC CCCGGCCCAG ACCATCTCCA ACGCCCCTGT CTCCGAGTAC 
ATGAACCAAG CCATGCTCTT TGGTAGGAAC CCACGCTACG AGAACGTGCC ACTAATCGGG 
AGAGCCTCCC CTCCGCCTAC GTACTCTCCC AGCATGAGAG CCACCTACCT GTCTGTGGCG 
GATGAGCACC TGAGGCACTA CGGGAATCAG TTTCCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH2 ( NM_032646.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_116035.5 Homo sapiens tweety family member 2 (TTYH2), transcript variant 1, mRNA.

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CloneID	OHu29367
Clone ID Related Accession (Same CDS sequence)	NM_032646.6 , NM_032646.5
Accession Version	NM_032646.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556640000000
Organism	Homo sapiens(human)
Product	protein tweety homolog 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF529231.1, BC005168.1, AF319952.1, AL831858.1, AK058197.1, AK126955.1 and BC004233.2. On Nov 22, 2018 this sequence version replaced NM_032646.5. Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803615.10951.1, SRR1660805.141609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000269346.9/ ENSP00000269346.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGGCGG CGCGCGTGGA CTACATCGCT CCCTGGTGGG TCGTGTGGCT GCACAGCGTC 
CCGCACGTCG GCCTGCGCCT GCAGCCCGTG AACAGCACCT TCAGCCCCGG CGACGAGAGT 
TACCAGGAGT CGCTGCTGTT CCTGGGGCTG GTGGCCGCCG TCTGCCTGGG CCTGAACCTC 
ATCTTCCTTG TGGCTTACCT GGTCTGTGCA TGCCACTGCC GGCGGGACGA TGCGGTGCAG 
ACCAAGCAGC ACCACTCCTG CTGCATCACC TGGACGGCCG TGGTGGCCGG GCTCATCTGC 
TGTGCTGCGG TGGGCGTTGG TTTCTATGGA AACAGCGAGA CCAACGATGG GGCGTACCAG 
CTGATGTACT CCTTGGACGA TGCCAACCAC ACCTTCTCTG GGATCGATGC TCTGGTTTCC 
GGAACTACCC AGAAGATGAA GGTGGACCTA GAGCAGCACC TGGCCCGGCT CAGTGAGATC 
TTTGCTGCCC GGGGCGATTA CCTGCAGACC CTGAAGTTCA TACAGCAGAT GGCGGGCAGC 
GTTGTTGTTC AGCTCTCAGG ACTGCCCGTG TGGAGGGAGG TCACCATGGA GCTGACCAAG 
CTATCCGACC AGACTGGCTA CGTGGAGTAC TACAGGTGGC TCTCCTACCT CCTGCTCTTT 
ATCCTGGACC TGGTCATCTG CCTCATTGCC TGCCTGGGAC TGGCCAAGCG CTCCAAGTGT 
CTCCTGGCCT CGATGCTGTG CTGTGGGGCA CTGAGCCTGC TCCTCAGTTG GGCATCCCTG 
GCCGCTGATG GCTCTGCGGC AGTGGCCACC AGTGACTTCT GTGTGGCTCC TGACACCTTC 
ATCCTGAACG TCACGGAGGG CCAGATCAGC ACAGAGGTGA CTCGCTACTA CCTGTATTGC 
AGCCAGAGTG GAAGCAGCCC CTTCCAGCAG ACCCTGACCA CCTTCCAGCG CGCACTTACC 
ACCATGCAGA TCCAGGTCGC GGGGCTGCTG CAGTTTGCCG TGCCCCTCTT CTCCACTGCA 
GAGGAAGACC TGCTTGCAAT CCAGCTCCTG CTGAACTCCT CAGAGTCCAG CCTTCACCAG 
CTGACCGCCA TGGTGGACTG CCGAGGGCTG CACAAGGATT ATCTGGACGC TCTTGCTGGC 
ATCTGCTACG ACGGCCTCCA GGGCTTGCTG TACCTTGGCC TCTTCTCCTT CCTGGCCGCC 
CTCGCCTTCT CCACCATGAT CTGTGCAGGG CCAAGGGCCT GGAAGCACTT CACCACCAGA 
AACAGAGACT ACGATGACAT TGATGATGAT GACCCCTTTA ACCCCCAAGC CTGGCGCATG 
GCGGCTCACA GTCCCCCGAG GGGACAGCTT CACAGCTTCT GCAGCTACAG CAGTGGCCTG 
GGAAGTCAGA CCAGCCTGCA GCCCCCGGCC CAGACCATCT CCAACGCCCC TGTCTCCGAG 
TACATGAACC AAGCCATGCT CTTTGGTAGG AACCCACGCT ACGAGAACGT GCCACTAATC 
GGGAGAGCCT CCCCTCCGCC TACGTACTCT CCCAGCATGA GAGCCACCTA CCTGTCTGTG 
GCGGATGAGC ACCTGAGGCA CTACGGGAAT CAGTTTCCAG CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116035.5
CDS	18..1622
Translation	MQAARVDYIAPWWVVWLHSVPHVGLRLQPVNSTFSPGDESYQESLLFLGLVAAVCLGLNLIFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQLMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGSVVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKCLLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYCSQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA

Target ORF information:

RefSeq Version	NM_032646.6
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 2 (TTYH2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032646.6

ORF Insert Sequence:

ATGCAGGCGG CGCGCGTGGA CTACATCGCT CCCTGGTGGG TCGTGTGGCT GCACAGCGTC 
CCGCACGTCG GCCTGCGCCT GCAGCCCGTG AACAGCACCT TCAGCCCCGG CGACGAGAGT 
TACCAGGAGT CGCTGCTGTT CCTGGGGCTG GTGGCCGCCG TCTGCCTGGG CCTGAACCTC 
ATCTTCCTTG TGGCTTACCT GGTCTGTGCA TGCCACTGCC GGCGGGACGA TGCGGTGCAG 
ACCAAGCAGC ACCACTCCTG CTGCATCACC TGGACGGCCG TGGTGGCCGG GCTCATCTGC 
TGTGCTGCGG TGGGCGTTGG TTTCTATGGA AACAGCGAGA CCAACGATGG GGCGTACCAG 
CTGATGTACT CCTTGGACGA TGCCAACCAC ACCTTCTCTG GGATCGATGC TCTGGTTTCC 
GGAACTACCC AGAAGATGAA GGTGGACCTA GAGCAGCACC TGGCCCGGCT CAGTGAGATC 
TTTGCTGCCC GGGGCGATTA CCTGCAGACC CTGAAGTTCA TACAGCAGAT GGCGGGCAGC 
GTTGTTGTTC AGCTCTCAGG ACTGCCCGTG TGGAGGGAGG TCACCATGGA GCTGACCAAG 
CTATCCGACC AGACTGGCTA CGTGGAGTAC TACAGGTGGC TCTCCTACCT CCTGCTCTTT 
ATCCTGGACC TGGTCATCTG CCTCATTGCC TGCCTGGGAC TGGCCAAGCG CTCCAAGTGT 
CTCCTGGCCT CGATGCTGTG CTGTGGGGCA CTGAGCCTGC TCCTCAGTTG GGCATCCCTG 
GCCGCTGATG GCTCTGCGGC AGTGGCCACC AGTGACTTCT GTGTGGCTCC TGACACCTTC 
ATCCTGAACG TCACGGAGGG CCAGATCAGC ACAGAGGTGA CTCGCTACTA CCTGTATTGC 
AGCCAGAGTG GAAGCAGCCC CTTCCAGCAG ACCCTGACCA CCTTCCAGCG CGCACTTACC 
ACCATGCAGA TCCAGGTCGC GGGGCTGCTG CAGTTTGCCG TGCCCCTCTT CTCCACTGCA 
GAGGAAGACC TGCTTGCAAT CCAGCTCCTG CTGAACTCCT CAGAGTCCAG CCTTCACCAG 
CTGACCGCCA TGGTGGACTG CCGAGGGCTG CACAAGGATT ATCTGGACGC TCTTGCTGGC 
ATCTGCTACG ACGGCCTCCA GGGCTTGCTG TACCTTGGCC TCTTCTCCTT CCTGGCCGCC 
CTCGCCTTCT CCACCATGAT CTGTGCAGGG CCAAGGGCCT GGAAGCACTT CACCACCAGA 
AACAGAGACT ACGATGACAT TGATGATGAT GACCCCTTTA ACCCCCAAGC CTGGCGCATG 
GCGGCTCACA GTCCCCCGAG GGGACAGCTT CACAGCTTCT GCAGCTACAG CAGTGGCCTG 
GGAAGTCAGA CCAGCCTGCA GCCCCCGGCC CAGACCATCT CCAACGCCCC TGTCTCCGAG 
TACATGAACC AAGCCATGCT CTTTGGTAGG AACCCACGCT ACGAGAACGT GCCACTAATC 
GGGAGAGCCT CCCCTCCGCC TACGTACTCT CCCAGCATGA GAGCCACCTA CCTGTCTGTG 
GCGGATGAGC ACCTGAGGCA CTACGGGAAT CAGTTTCCAG CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH2 ( NM_032646.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_116035.5 Homo sapiens tweety family member 2 (TTYH2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29367
Clone ID Related Accession (Same CDS sequence)	NM_032646.6 , NM_032646.5
Accession Version	NM_032646.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Homo sapiens(human)
Product	protein tweety homolog 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF529231.1, BC005168.1, AF319952.1, AL831858.1, AK058197.1, AK126955.1 and BC004233.2. On Oct 8, 2004 this sequence version replaced NM_032646.4. Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803615.196589.1, SRR1660805.141609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGCGG CGCGCGTGGA CTACATCGCT CCCTGGTGGG TCGTGTGGCT GCACAGCGTC 
CCGCACGTCG GCCTGCGCCT GCAGCCCGTG AACAGCACCT TCAGCCCCGG CGACGAGAGT 
TACCAGGAGT CGCTGCTGTT CCTGGGGCTG GTGGCCGCCG TCTGCCTGGG CCTGAACCTC 
ATCTTCCTTG TGGCTTACCT GGTCTGTGCA TGCCACTGCC GGCGGGACGA TGCGGTGCAG 
ACCAAGCAGC ACCACTCCTG CTGCATCACC TGGACGGCCG TGGTGGCCGG GCTCATCTGC 
TGTGCTGCGG TGGGCGTTGG TTTCTATGGA AACAGCGAGA CCAACGATGG GGCGTACCAG 
CTGATGTACT CCTTGGACGA TGCCAACCAC ACCTTCTCTG GGATCGATGC TCTGGTTTCC 
GGAACTACCC AGAAGATGAA GGTGGACCTA GAGCAGCACC TGGCCCGGCT CAGTGAGATC 
TTTGCTGCCC GGGGCGATTA CCTGCAGACC CTGAAGTTCA TACAGCAGAT GGCGGGCAGC 
GTTGTTGTTC AGCTCTCAGG ACTGCCCGTG TGGAGGGAGG TCACCATGGA GCTGACCAAG 
CTATCCGACC AGACTGGCTA CGTGGAGTAC TACAGGTGGC TCTCCTACCT CCTGCTCTTT 
ATCCTGGACC TGGTCATCTG CCTCATTGCC TGCCTGGGAC TGGCCAAGCG CTCCAAGTGT 
CTCCTGGCCT CGATGCTGTG CTGTGGGGCA CTGAGCCTGC TCCTCAGTTG GGCATCCCTG 
GCCGCTGATG GCTCTGCGGC AGTGGCCACC AGTGACTTCT GTGTGGCTCC TGACACCTTC 
ATCCTGAACG TCACGGAGGG CCAGATCAGC ACAGAGGTGA CTCGCTACTA CCTGTATTGC 
AGCCAGAGTG GAAGCAGCCC CTTCCAGCAG ACCCTGACCA CCTTCCAGCG CGCACTTACC 
ACCATGCAGA TCCAGGTCGC GGGGCTGCTG CAGTTTGCCG TGCCCCTCTT CTCCACTGCA 
GAGGAAGACC TGCTTGCAAT CCAGCTCCTG CTGAACTCCT CAGAGTCCAG CCTTCACCAG 
CTGACCGCCA TGGTGGACTG CCGAGGGCTG CACAAGGATT ATCTGGACGC TCTTGCTGGC 
ATCTGCTACG ACGGCCTCCA GGGCTTGCTG TACCTTGGCC TCTTCTCCTT CCTGGCCGCC 
CTCGCCTTCT CCACCATGAT CTGTGCAGGG CCAAGGGCCT GGAAGCACTT CACCACCAGA 
AACAGAGACT ACGATGACAT TGATGATGAT GACCCCTTTA ACCCCCAAGC CTGGCGCATG 
GCGGCTCACA GTCCCCCGAG GGGACAGCTT CACAGCTTCT GCAGCTACAG CAGTGGCCTG 
GGAAGTCAGA CCAGCCTGCA GCCCCCGGCC CAGACCATCT CCAACGCCCC TGTCTCCGAG 
TACATGAACC AAGCCATGCT CTTTGGTAGG AACCCACGCT ACGAGAACGT GCCACTAATC 
GGGAGAGCCT CCCCTCCGCC TACGTACTCT CCCAGCATGA GAGCCACCTA CCTGTCTGTG 
GCGGATGAGC ACCTGAGGCA CTACGGGAAT CAGTTTCCAG CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116035.5
CDS	32..1636
Translation	MQAARVDYIAPWWVVWLHSVPHVGLRLQPVNSTFSPGDESYQESLLFLGLVAAVCLGLNLIFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQLMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGSVVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKCLLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYCSQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA

Target ORF information:

RefSeq Version	NM_032646.5
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 2 (TTYH2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032646.5

ORF Insert Sequence:

ATGCAGGCGG CGCGCGTGGA CTACATCGCT CCCTGGTGGG TCGTGTGGCT GCACAGCGTC 
CCGCACGTCG GCCTGCGCCT GCAGCCCGTG AACAGCACCT TCAGCCCCGG CGACGAGAGT 
TACCAGGAGT CGCTGCTGTT CCTGGGGCTG GTGGCCGCCG TCTGCCTGGG CCTGAACCTC 
ATCTTCCTTG TGGCTTACCT GGTCTGTGCA TGCCACTGCC GGCGGGACGA TGCGGTGCAG 
ACCAAGCAGC ACCACTCCTG CTGCATCACC TGGACGGCCG TGGTGGCCGG GCTCATCTGC 
TGTGCTGCGG TGGGCGTTGG TTTCTATGGA AACAGCGAGA CCAACGATGG GGCGTACCAG 
CTGATGTACT CCTTGGACGA TGCCAACCAC ACCTTCTCTG GGATCGATGC TCTGGTTTCC 
GGAACTACCC AGAAGATGAA GGTGGACCTA GAGCAGCACC TGGCCCGGCT CAGTGAGATC 
TTTGCTGCCC GGGGCGATTA CCTGCAGACC CTGAAGTTCA TACAGCAGAT GGCGGGCAGC 
GTTGTTGTTC AGCTCTCAGG ACTGCCCGTG TGGAGGGAGG TCACCATGGA GCTGACCAAG 
CTATCCGACC AGACTGGCTA CGTGGAGTAC TACAGGTGGC TCTCCTACCT CCTGCTCTTT 
ATCCTGGACC TGGTCATCTG CCTCATTGCC TGCCTGGGAC TGGCCAAGCG CTCCAAGTGT 
CTCCTGGCCT CGATGCTGTG CTGTGGGGCA CTGAGCCTGC TCCTCAGTTG GGCATCCCTG 
GCCGCTGATG GCTCTGCGGC AGTGGCCACC AGTGACTTCT GTGTGGCTCC TGACACCTTC 
ATCCTGAACG TCACGGAGGG CCAGATCAGC ACAGAGGTGA CTCGCTACTA CCTGTATTGC 
AGCCAGAGTG GAAGCAGCCC CTTCCAGCAG ACCCTGACCA CCTTCCAGCG CGCACTTACC 
ACCATGCAGA TCCAGGTCGC GGGGCTGCTG CAGTTTGCCG TGCCCCTCTT CTCCACTGCA 
GAGGAAGACC TGCTTGCAAT CCAGCTCCTG CTGAACTCCT CAGAGTCCAG CCTTCACCAG 
CTGACCGCCA TGGTGGACTG CCGAGGGCTG CACAAGGATT ATCTGGACGC TCTTGCTGGC 
ATCTGCTACG ACGGCCTCCA GGGCTTGCTG TACCTTGGCC TCTTCTCCTT CCTGGCCGCC 
CTCGCCTTCT CCACCATGAT CTGTGCAGGG CCAAGGGCCT GGAAGCACTT CACCACCAGA 
AACAGAGACT ACGATGACAT TGATGATGAT GACCCCTTTA ACCCCCAAGC CTGGCGCATG 
GCGGCTCACA GTCCCCCGAG GGGACAGCTT CACAGCTTCT GCAGCTACAG CAGTGGCCTG 
GGAAGTCAGA CCAGCCTGCA GCCCCCGGCC CAGACCATCT CCAACGCCCC TGTCTCCGAG 
TACATGAACC AAGCCATGCT CTTTGGTAGG AACCCACGCT ACGAGAACGT GCCACTAATC 
GGGAGAGCCT CCCCTCCGCC TACGTACTCT CCCAGCATGA GAGCCACCTA CCTGTCTGTG 
GCGGATGAGC ACCTGAGGCA CTACGGGAAT CAGTTTCCAG CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.
The Journal of biological chemistry283(35)24000-10(2008 Aug)
He Y,Hryciw DH,Carroll ML,Myers SA,Whitbread AK,Kumar S,Poronnik P,Hooper JD

N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).
The Biochemical journal412(1)45-55(2008 May)
He Y,Ramsay AJ,Hunt ML,Whitbread AK,Myers SA,Hooper JD

TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is up-regulated in colon carcinoma and involved in cell proliferation and cell aggregation.
World journal of gastroenterology13(19)2717-21(2007 May)
Toiyama Y,Mizoguchi A,Kimura K,Hiro J,Inoue Y,Tutumi T,Miki C,Kusunoki M

A novel human Cl(-) channel family related to Drosophila flightless locus.
The Journal of biological chemistry279(21)22461-8(2004 May)
Suzuki M,Mizuno A

A novel proteomic approach for specific identification of tyrosine kinase substrates using [13C]tyrosine.
The Journal of biological chemistry279(16)15805-13(2004 Apr)
Ibarrola N,Molina H,Iwahori A,Pandey A

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TTYH2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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