| Gene Symbol | DPH7 |
| Entrez Gene ID | 92715 |
| Full Name | diphthamide biosynthesis 7 |
| Synonyms | C9orf112,RRT2,WDR85 |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | Diphthamide is a post-translationally modified histidine residue present in elongation factor 2, and is the target of diphtheria toxin. This gene encodes a protein that contains a WD-40 domain, and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase, converting methylated diphthine to diphthine, which can then undergo amidation to produce diphthamide. [provided by RefSeq, Oct 2016]. |
| Disorder MIM: |
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