LHX4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LHX4
Entrez Gene ID	89884
Full Name	LIM homeobox 4
Synonyms	CPHD4
General protein information	Preferred Names LIM homeobox 4 Names LIM/homeobox protein Lhx4 LIM homeobox protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q25.2
Summary	This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4. [provided by RefSeq, Dec 2010].
Disorder MIM:	602146
Disorder Html:	Pituitary hormone deficiency, combined, 4, 262700 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011510106.3	XP_011508408.1	LIM/homeobox protein Lhx4 isoform X1
XM_017002755.1	XP_016858244.1	LIM/homeobox protein Lhx4 isoform X2
XM_011510105.2	XP_011508407.1	LIM/homeobox protein Lhx4 isoform X1
XM_011510106.2	XP_011508408.1	LIM/homeobox protein Lhx4 isoform X1
NM_033343.4	NP_203129.1	LIM/homeobox protein Lhx4
XM_011510108.2	XP_011508410.1	LIM/homeobox protein Lhx4 isoform X2
NM_033343.3	NP_203129.1	LIM/homeobox protein Lhx4

Pathways from BioSystems

Homologies

Homo sapiens (human)	LHX4	NP_203129.1
Pan troglodytes (chimpanzee)	LHX4	XP_524984.3
Mus musculus (house mouse)	Lhx4	NP_034842.2
Danio rerio (zebrafish)	lhx4	NP_001116445.1
Macaca mulatta (Rhesus monkey)	LOC716454	XP_001115086.1
Canis lupus familiaris (dog)	LHX4	XP_547420.2
Bos taurus (cattle)	LHX4	NP_001179714.1
Gallus gallus (chicken)	LHX4	XP_001235592.3
Rattus norvegicus (Norway rat)	Lhx4	NP_001101818.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J
Science (New York, N.Y.)356(6337)(2017 05)

Contribution of LHX4 Mutations to Pituitary Deficits in a Cohort of 417 Unrelated Patients.
Cohen E, Maghnie M, Collot N, Leger J, Dastot F, Polak M, Rose S, Touraine P, Duquesnoy P, Tauber M, Copin B, Bertrand AM, Brioude F, Larizza D, Edouard T, González Briceño L, Netchine I, Oliver-Petit I, Sobrier ML, Amselem S, Legendre M
The Journal of clinical endocrinology and metabolism102(1)290-301(2017 01)

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LHX4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LHX4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu74131	XM_011510106.3 Latest version!	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu74131	XM_011510105.2 Latest version!	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu74132	XM_017002755.1 Latest version!	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu74132	XM_011510108.2 Latest version!	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu22868	NM_033343.4 Latest version!	Homo sapiens LIM homeobox 4 (LHX4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu74131	XM_011510106.2	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu22868	NM_033343.3	Homo sapiens LIM homeobox 4 (LHX4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LHX4 ( XM_011510106.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508408.1 Homo sapiens LIM homeobox 4 (LHX4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu74131
Clone ID Related Accession (Same CDS sequence)	XM_011510106.3 , XM_011510105.2 , XM_011510106.2
Accession Version	XM_011510106.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011510106.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCTGG CGGACAGGTG CTTCTCCAGG GCTGGGAGCG TCTACTGCAA GGAGGACTTC 
TTCAAGCGCT TCGGCACAAA ATGCACGGCC TGCCAGCAGG GTATCCCCCC AACCCAGGTG 
GTCCGCAAGG CCCAGGACTT TGTCTACCAC CTGCACTGCT TTGCTTGCAT CATCTGCAAC 
CGGCAGCTGG CCACGGGGGA CGAATTCTAC CTCATGGAGG ACGGGCGGCT GGTGTGCAAG 
GAAGACTACG AGACAGCCAA GCAGAACGAT GACTCAGAGG CTGGAGCTAA GCGGCCCCGG 
ACCACCATCA CAGCCAAGCA GCTGGAGACA TTAAAGAATG CATACAAGAA CTCCCCCAAG 
CCTGCCCGGC ACGTGAGGGA GCAGCTGTCC TCAGAGACAG GCCTGGACAT GAGGGTCGTA 
CAGGTTTGGT TTCAGAACAG AAGGGCCAAA GAGAAACGCC TGAAGAAGGA TGCAGGGCGG 
CACCGCTGGG GGCAGTTCTA TAAGAGCGTC AAGAGGAGCC GGGGCAGCAG CAAGCAGGAG 
AAGGAGAGCT CTGCAGAGGA CTGTGGGGTT AGTGACAGTG AGCTGAGCTT CCGAGAGGAT 
CAAATTCTCT CAGAACTTGG CCACACCAAT AGGATTTATG GCAACGTGGG GGACGTTACA 
GGCGGACAGT TAATGAATGG GAGCTTCTCC ATGGACGGGA CAGGACAATC CTATCAGGAC 
TTGAGGGATG GGAGCCCCTA TGGAATCCCC CAGTCTCCAT CCTCCATATC GTCCCTGCCA 
TCCCACGCTC CTTTGCTCAA TGGGCTGGAT TACACGGTGG ACAGTAATTT GGGCATCATT 
GCGCATGCAG GGCAGGGAGT AAGCCAGACG CTGAGAGCCA TGGCTGGGGG ACCCACCTCT 
GACATCTCCA CAGGAAGCAG TGTAGGCTAT CCCGACTTTC CAACTAGCCC AGGCTCTTGG 
CTCGATGAAA TGGATCATCC TCCTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508408.1
CDS	264..1253
Translation	MQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF

Target ORF information:

RefSeq Version	XM_011510106.3
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510106.3

ORF Insert Sequence:

ATGCAGCTGG CGGACAGGTG CTTCTCCAGG GCTGGGAGCG TCTACTGCAA GGAGGACTTC 
TTCAAGCGCT TCGGCACAAA ATGCACGGCC TGCCAGCAGG GTATCCCCCC AACCCAGGTG 
GTCCGCAAGG CCCAGGACTT TGTCTACCAC CTGCACTGCT TTGCTTGCAT CATCTGCAAC 
CGGCAGCTGG CCACGGGGGA CGAATTCTAC CTCATGGAGG ACGGGCGGCT GGTGTGCAAG 
GAAGACTACG AGACAGCCAA GCAGAACGAT GACTCAGAGG CTGGAGCTAA GCGGCCCCGG 
ACCACCATCA CAGCCAAGCA GCTGGAGACA TTAAAGAATG CATACAAGAA CTCCCCCAAG 
CCTGCCCGGC ACGTGAGGGA GCAGCTGTCC TCAGAGACAG GCCTGGACAT GAGGGTCGTA 
CAGGTTTGGT TTCAGAACAG AAGGGCCAAA GAGAAACGCC TGAAGAAGGA TGCAGGGCGG 
CACCGCTGGG GGCAGTTCTA TAAGAGCGTC AAGAGGAGCC GGGGCAGCAG CAAGCAGGAG 
AAGGAGAGCT CTGCAGAGGA CTGTGGGGTT AGTGACAGTG AGCTGAGCTT CCGAGAGGAT 
CAAATTCTCT CAGAACTTGG CCACACCAAT AGGATTTATG GCAACGTGGG GGACGTTACA 
GGCGGACAGT TAATGAATGG GAGCTTCTCC ATGGACGGGA CAGGACAATC CTATCAGGAC 
TTGAGGGATG GGAGCCCCTA TGGAATCCCC CAGTCTCCAT CCTCCATATC GTCCCTGCCA 
TCCCACGCTC CTTTGCTCAA TGGGCTGGAT TACACGGTGG ACAGTAATTT GGGCATCATT 
GCGCATGCAG GGCAGGGAGT AAGCCAGACG CTGAGAGCCA TGGCTGGGGG ACCCACCTCT 
GACATCTCCA CAGGAAGCAG TGTAGGCTAT CCCGACTTTC CAACTAGCCC AGGCTCTTGG 
CTCGATGAAA TGGATCATCC TCCTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX4 ( XM_011510105.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508407.1 Homo sapiens LIM homeobox 4 (LHX4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu74131
Clone ID Related Accession (Same CDS sequence)	XM_011510106.3 , XM_011510105.2 , XM_011510106.2
Accession Version	XM_011510105.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011510105.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCTGG CGGACAGGTG CTTCTCCAGG GCTGGGAGCG TCTACTGCAA GGAGGACTTC 
TTCAAGCGCT TCGGCACAAA ATGCACGGCC TGCCAGCAGG GTATCCCCCC AACCCAGGTG 
GTCCGCAAGG CCCAGGACTT TGTCTACCAC CTGCACTGCT TTGCTTGCAT CATCTGCAAC 
CGGCAGCTGG CCACGGGGGA CGAATTCTAC CTCATGGAGG ACGGGCGGCT GGTGTGCAAG 
GAAGACTACG AGACAGCCAA GCAGAACGAT GACTCAGAGG CTGGAGCTAA GCGGCCCCGG 
ACCACCATCA CAGCCAAGCA GCTGGAGACA TTAAAGAATG CATACAAGAA CTCCCCCAAG 
CCTGCCCGGC ACGTGAGGGA GCAGCTGTCC TCAGAGACAG GCCTGGACAT GAGGGTCGTA 
CAGGTTTGGT TTCAGAACAG AAGGGCCAAA GAGAAACGCC TGAAGAAGGA TGCAGGGCGG 
CACCGCTGGG GGCAGTTCTA TAAGAGCGTC AAGAGGAGCC GGGGCAGCAG CAAGCAGGAG 
AAGGAGAGCT CTGCAGAGGA CTGTGGGGTT AGTGACAGTG AGCTGAGCTT CCGAGAGGAT 
CAAATTCTCT CAGAACTTGG CCACACCAAT AGGATTTATG GCAACGTGGG GGACGTTACA 
GGCGGACAGT TAATGAATGG GAGCTTCTCC ATGGACGGGA CAGGACAATC CTATCAGGAC 
TTGAGGGATG GGAGCCCCTA TGGAATCCCC CAGTCTCCAT CCTCCATATC GTCCCTGCCA 
TCCCACGCTC CTTTGCTCAA TGGGCTGGAT TACACGGTGG ACAGTAATTT GGGCATCATT 
GCGCATGCAG GGCAGGGAGT AAGCCAGACG CTGAGAGCCA TGGCTGGGGG ACCCACCTCT 
GACATCTCCA CAGGAAGCAG TGTAGGCTAT CCCGACTTTC CAACTAGCCC AGGCTCTTGG 
CTCGATGAAA TGGATCATCC TCCTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508407.1
CDS	650..1639
Translation	MQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF

Target ORF information:

RefSeq Version	XM_011510105.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510105.2

ORF Insert Sequence:

ATGCAGCTGG CGGACAGGTG CTTCTCCAGG GCTGGGAGCG TCTACTGCAA GGAGGACTTC 
TTCAAGCGCT TCGGCACAAA ATGCACGGCC TGCCAGCAGG GTATCCCCCC AACCCAGGTG 
GTCCGCAAGG CCCAGGACTT TGTCTACCAC CTGCACTGCT TTGCTTGCAT CATCTGCAAC 
CGGCAGCTGG CCACGGGGGA CGAATTCTAC CTCATGGAGG ACGGGCGGCT GGTGTGCAAG 
GAAGACTACG AGACAGCCAA GCAGAACGAT GACTCAGAGG CTGGAGCTAA GCGGCCCCGG 
ACCACCATCA CAGCCAAGCA GCTGGAGACA TTAAAGAATG CATACAAGAA CTCCCCCAAG 
CCTGCCCGGC ACGTGAGGGA GCAGCTGTCC TCAGAGACAG GCCTGGACAT GAGGGTCGTA 
CAGGTTTGGT TTCAGAACAG AAGGGCCAAA GAGAAACGCC TGAAGAAGGA TGCAGGGCGG 
CACCGCTGGG GGCAGTTCTA TAAGAGCGTC AAGAGGAGCC GGGGCAGCAG CAAGCAGGAG 
AAGGAGAGCT CTGCAGAGGA CTGTGGGGTT AGTGACAGTG AGCTGAGCTT CCGAGAGGAT 
CAAATTCTCT CAGAACTTGG CCACACCAAT AGGATTTATG GCAACGTGGG GGACGTTACA 
GGCGGACAGT TAATGAATGG GAGCTTCTCC ATGGACGGGA CAGGACAATC CTATCAGGAC 
TTGAGGGATG GGAGCCCCTA TGGAATCCCC CAGTCTCCAT CCTCCATATC GTCCCTGCCA 
TCCCACGCTC CTTTGCTCAA TGGGCTGGAT TACACGGTGG ACAGTAATTT GGGCATCATT 
GCGCATGCAG GGCAGGGAGT AAGCCAGACG CTGAGAGCCA TGGCTGGGGG ACCCACCTCT 
GACATCTCCA CAGGAAGCAG TGTAGGCTAT CCCGACTTTC CAACTAGCCC AGGCTCTTGG 
CTCGATGAAA TGGATCATCC TCCTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX4 ( XM_011510106.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508408.1 Homo sapiens LIM homeobox 4 (LHX4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu74131
Clone ID Related Accession (Same CDS sequence)	XM_011510106.3 , XM_011510105.2 , XM_011510106.2
Accession Version	XM_011510106.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011510106.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCTGG CGGACAGGTG CTTCTCCAGG GCTGGGAGCG TCTACTGCAA GGAGGACTTC 
TTCAAGCGCT TCGGCACAAA ATGCACGGCC TGCCAGCAGG GTATCCCCCC AACCCAGGTG 
GTCCGCAAGG CCCAGGACTT TGTCTACCAC CTGCACTGCT TTGCTTGCAT CATCTGCAAC 
CGGCAGCTGG CCACGGGGGA CGAATTCTAC CTCATGGAGG ACGGGCGGCT GGTGTGCAAG 
GAAGACTACG AGACAGCCAA GCAGAACGAT GACTCAGAGG CTGGAGCTAA GCGGCCCCGG 
ACCACCATCA CAGCCAAGCA GCTGGAGACA TTAAAGAATG CATACAAGAA CTCCCCCAAG 
CCTGCCCGGC ACGTGAGGGA GCAGCTGTCC TCAGAGACAG GCCTGGACAT GAGGGTCGTA 
CAGGTTTGGT TTCAGAACAG AAGGGCCAAA GAGAAACGCC TGAAGAAGGA TGCAGGGCGG 
CACCGCTGGG GGCAGTTCTA TAAGAGCGTC AAGAGGAGCC GGGGCAGCAG CAAGCAGGAG 
AAGGAGAGCT CTGCAGAGGA CTGTGGGGTT AGTGACAGTG AGCTGAGCTT CCGAGAGGAT 
CAAATTCTCT CAGAACTTGG CCACACCAAT AGGATTTATG GCAACGTGGG GGACGTTACA 
GGCGGACAGT TAATGAATGG GAGCTTCTCC ATGGACGGGA CAGGACAATC CTATCAGGAC 
TTGAGGGATG GGAGCCCCTA TGGAATCCCC CAGTCTCCAT CCTCCATATC GTCCCTGCCA 
TCCCACGCTC CTTTGCTCAA TGGGCTGGAT TACACGGTGG ACAGTAATTT GGGCATCATT 
GCGCATGCAG GGCAGGGAGT AAGCCAGACG CTGAGAGCCA TGGCTGGGGG ACCCACCTCT 
GACATCTCCA CAGGAAGCAG TGTAGGCTAT CCCGACTTTC CAACTAGCCC AGGCTCTTGG 
CTCGATGAAA TGGATCATCC TCCTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508408.1
CDS	273..1262
Translation	MQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF

Target ORF information:

RefSeq Version	XM_011510106.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510106.2

ORF Insert Sequence:

ATGCAGCTGG CGGACAGGTG CTTCTCCAGG GCTGGGAGCG TCTACTGCAA GGAGGACTTC 
TTCAAGCGCT TCGGCACAAA ATGCACGGCC TGCCAGCAGG GTATCCCCCC AACCCAGGTG 
GTCCGCAAGG CCCAGGACTT TGTCTACCAC CTGCACTGCT TTGCTTGCAT CATCTGCAAC 
CGGCAGCTGG CCACGGGGGA CGAATTCTAC CTCATGGAGG ACGGGCGGCT GGTGTGCAAG 
GAAGACTACG AGACAGCCAA GCAGAACGAT GACTCAGAGG CTGGAGCTAA GCGGCCCCGG 
ACCACCATCA CAGCCAAGCA GCTGGAGACA TTAAAGAATG CATACAAGAA CTCCCCCAAG 
CCTGCCCGGC ACGTGAGGGA GCAGCTGTCC TCAGAGACAG GCCTGGACAT GAGGGTCGTA 
CAGGTTTGGT TTCAGAACAG AAGGGCCAAA GAGAAACGCC TGAAGAAGGA TGCAGGGCGG 
CACCGCTGGG GGCAGTTCTA TAAGAGCGTC AAGAGGAGCC GGGGCAGCAG CAAGCAGGAG 
AAGGAGAGCT CTGCAGAGGA CTGTGGGGTT AGTGACAGTG AGCTGAGCTT CCGAGAGGAT 
CAAATTCTCT CAGAACTTGG CCACACCAAT AGGATTTATG GCAACGTGGG GGACGTTACA 
GGCGGACAGT TAATGAATGG GAGCTTCTCC ATGGACGGGA CAGGACAATC CTATCAGGAC 
TTGAGGGATG GGAGCCCCTA TGGAATCCCC CAGTCTCCAT CCTCCATATC GTCCCTGCCA 
TCCCACGCTC CTTTGCTCAA TGGGCTGGAT TACACGGTGG ACAGTAATTT GGGCATCATT 
GCGCATGCAG GGCAGGGAGT AAGCCAGACG CTGAGAGCCA TGGCTGGGGG ACCCACCTCT 
GACATCTCCA CAGGAAGCAG TGTAGGCTAT CCCGACTTTC CAACTAGCCC AGGCTCTTGG 
CTCGATGAAA TGGATCATCC TCCTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX4 ( XM_017002755.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016858244.1 Homo sapiens LIM homeobox 4 (LHX4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu74132
Clone ID Related Accession (Same CDS sequence)	XM_017002755.1 , XM_011510108.2
Accession Version	XM_017002755.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCAG AGAGGACCAG ACGGCGCTTC GGCACAAAAT GCACGGCCTG CCAGCAGGGT 
ATCCCCCCAA CCCAGGTGGT CCGCAAGGCC CAGGACTTTG TCTACCACCT GCACTGCTTT 
GCTTGCATCA TCTGCAACCG GCAGCTGGCC ACGGGGGACG AATTCTACCT CATGGAGGAC 
GGGCGGCTGG TGTGCAAGGA AGACTACGAG ACAGCCAAGC AGAACGATGA CTCAGAGGCT 
GGAGCTAAGC GGCCCCGGAC CACCATCACA GCCAAGCAGC TGGAGACATT AAAGAATGCA 
TACAAGAACT CCCCCAAGCC TGCCCGGCAC GTGAGGGAGC AGCTGTCCTC AGAGACAGGC 
CTGGACATGA GGGTCGTACA GGTTTGGTTT CAGAACAGAA GGGCCAAAGA GAAACGCCTG 
AAGAAGGATG CAGGGCGGCA CCGCTGGGGG CAGTTCTATA AGAGCGTCAA GAGGAGCCGG 
GGCAGCAGCA AGCAGGAGAA GGAGAGCTCT GCAGAGGACT GTGGGGTTAG TGACAGTGAG 
CTGAGCTTCC GAGAGGATCA AATTCTCTCA GAACTTGGCC ACACCAATAG GATTTATGGC 
AACGTGGGGG ACGTTACAGG CGGACAGTTA ATGAATGGGA GCTTCTCCAT GGACGGGACA 
GGACAATCCT ATCAGGACTT GAGGGATGGG AGCCCCTATG GAATCCCCCA GTCTCCATCC 
TCCATATCGT CCCTGCCATC CCACGCTCCT TTGCTCAATG GGCTGGATTA CACGGTGGAC 
AGTAATTTGG GCATCATTGC GCATGCAGGG CAGGGAGTAA GCCAGACGCT GAGAGCCATG 
GCTGGGGGAC CCACCTCTGA CATCTCCACA GGAAGCAGTG TAGGCTATCC CGACTTTCCA 
ACTAGCCCAG GCTCTTGGCT CGATGAAATG GATCATCCTC CTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016858244.1
CDS	810..1757
Translation	MEAERTRRRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF

Target ORF information:

RefSeq Version	XM_017002755.1
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017002755.1

ORF Insert Sequence:

ATGGAGGCAG AGAGGACCAG ACGGCGCTTC GGCACAAAAT GCACGGCCTG CCAGCAGGGT 
ATCCCCCCAA CCCAGGTGGT CCGCAAGGCC CAGGACTTTG TCTACCACCT GCACTGCTTT 
GCTTGCATCA TCTGCAACCG GCAGCTGGCC ACGGGGGACG AATTCTACCT CATGGAGGAC 
GGGCGGCTGG TGTGCAAGGA AGACTACGAG ACAGCCAAGC AGAACGATGA CTCAGAGGCT 
GGAGCTAAGC GGCCCCGGAC CACCATCACA GCCAAGCAGC TGGAGACATT AAAGAATGCA 
TACAAGAACT CCCCCAAGCC TGCCCGGCAC GTGAGGGAGC AGCTGTCCTC AGAGACAGGC 
CTGGACATGA GGGTCGTACA GGTTTGGTTT CAGAACAGAA GGGCCAAAGA GAAACGCCTG 
AAGAAGGATG CAGGGCGGCA CCGCTGGGGG CAGTTCTATA AGAGCGTCAA GAGGAGCCGG 
GGCAGCAGCA AGCAGGAGAA GGAGAGCTCT GCAGAGGACT GTGGGGTTAG TGACAGTGAG 
CTGAGCTTCC GAGAGGATCA AATTCTCTCA GAACTTGGCC ACACCAATAG GATTTATGGC 
AACGTGGGGG ACGTTACAGG CGGACAGTTA ATGAATGGGA GCTTCTCCAT GGACGGGACA 
GGACAATCCT ATCAGGACTT GAGGGATGGG AGCCCCTATG GAATCCCCCA GTCTCCATCC 
TCCATATCGT CCCTGCCATC CCACGCTCCT TTGCTCAATG GGCTGGATTA CACGGTGGAC 
AGTAATTTGG GCATCATTGC GCATGCAGGG CAGGGAGTAA GCCAGACGCT GAGAGCCATG 
GCTGGGGGAC CCACCTCTGA CATCTCCACA GGAAGCAGTG TAGGCTATCC CGACTTTCCA 
ACTAGCCCAG GCTCTTGGCT CGATGAAATG GATCATCCTC CTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX4 ( XM_011510108.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508410.1 Homo sapiens LIM homeobox 4 (LHX4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu74132
Clone ID Related Accession (Same CDS sequence)	XM_017002755.1 , XM_011510108.2
Accession Version	XM_011510108.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011510108.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCAG AGAGGACCAG ACGGCGCTTC GGCACAAAAT GCACGGCCTG CCAGCAGGGT 
ATCCCCCCAA CCCAGGTGGT CCGCAAGGCC CAGGACTTTG TCTACCACCT GCACTGCTTT 
GCTTGCATCA TCTGCAACCG GCAGCTGGCC ACGGGGGACG AATTCTACCT CATGGAGGAC 
GGGCGGCTGG TGTGCAAGGA AGACTACGAG ACAGCCAAGC AGAACGATGA CTCAGAGGCT 
GGAGCTAAGC GGCCCCGGAC CACCATCACA GCCAAGCAGC TGGAGACATT AAAGAATGCA 
TACAAGAACT CCCCCAAGCC TGCCCGGCAC GTGAGGGAGC AGCTGTCCTC AGAGACAGGC 
CTGGACATGA GGGTCGTACA GGTTTGGTTT CAGAACAGAA GGGCCAAAGA GAAACGCCTG 
AAGAAGGATG CAGGGCGGCA CCGCTGGGGG CAGTTCTATA AGAGCGTCAA GAGGAGCCGG 
GGCAGCAGCA AGCAGGAGAA GGAGAGCTCT GCAGAGGACT GTGGGGTTAG TGACAGTGAG 
CTGAGCTTCC GAGAGGATCA AATTCTCTCA GAACTTGGCC ACACCAATAG GATTTATGGC 
AACGTGGGGG ACGTTACAGG CGGACAGTTA ATGAATGGGA GCTTCTCCAT GGACGGGACA 
GGACAATCCT ATCAGGACTT GAGGGATGGG AGCCCCTATG GAATCCCCCA GTCTCCATCC 
TCCATATCGT CCCTGCCATC CCACGCTCCT TTGCTCAATG GGCTGGATTA CACGGTGGAC 
AGTAATTTGG GCATCATTGC GCATGCAGGG CAGGGAGTAA GCCAGACGCT GAGAGCCATG 
GCTGGGGGAC CCACCTCTGA CATCTCCACA GGAAGCAGTG TAGGCTATCC CGACTTTCCA 
ACTAGCCCAG GCTCTTGGCT CGATGAAATG GATCATCCTC CTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508410.1
CDS	98..1045
Translation	MEAERTRRRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF

Target ORF information:

RefSeq Version	XM_011510108.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 4 (LHX4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510108.2

ORF Insert Sequence:

ATGGAGGCAG AGAGGACCAG ACGGCGCTTC GGCACAAAAT GCACGGCCTG CCAGCAGGGT 
ATCCCCCCAA CCCAGGTGGT CCGCAAGGCC CAGGACTTTG TCTACCACCT GCACTGCTTT 
GCTTGCATCA TCTGCAACCG GCAGCTGGCC ACGGGGGACG AATTCTACCT CATGGAGGAC 
GGGCGGCTGG TGTGCAAGGA AGACTACGAG ACAGCCAAGC AGAACGATGA CTCAGAGGCT 
GGAGCTAAGC GGCCCCGGAC CACCATCACA GCCAAGCAGC TGGAGACATT AAAGAATGCA 
TACAAGAACT CCCCCAAGCC TGCCCGGCAC GTGAGGGAGC AGCTGTCCTC AGAGACAGGC 
CTGGACATGA GGGTCGTACA GGTTTGGTTT CAGAACAGAA GGGCCAAAGA GAAACGCCTG 
AAGAAGGATG CAGGGCGGCA CCGCTGGGGG CAGTTCTATA AGAGCGTCAA GAGGAGCCGG 
GGCAGCAGCA AGCAGGAGAA GGAGAGCTCT GCAGAGGACT GTGGGGTTAG TGACAGTGAG 
CTGAGCTTCC GAGAGGATCA AATTCTCTCA GAACTTGGCC ACACCAATAG GATTTATGGC 
AACGTGGGGG ACGTTACAGG CGGACAGTTA ATGAATGGGA GCTTCTCCAT GGACGGGACA 
GGACAATCCT ATCAGGACTT GAGGGATGGG AGCCCCTATG GAATCCCCCA GTCTCCATCC 
TCCATATCGT CCCTGCCATC CCACGCTCCT TTGCTCAATG GGCTGGATTA CACGGTGGAC 
AGTAATTTGG GCATCATTGC GCATGCAGGG CAGGGAGTAA GCCAGACGCT GAGAGCCATG 
GCTGGGGGAC CCACCTCTGA CATCTCCACA GGAAGCAGTG TAGGCTATCC CGACTTTCCA 
ACTAGCCCAG GCTCTTGGCT CGATGAAATG GATCATCCTC CTTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX4 ( NM_033343.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_203129.1 Homo sapiens LIM homeobox 4 (LHX4), mRNA.

Price & Availability↑

CloneID	OHu22868
Clone ID Related Accession (Same CDS sequence)	NM_033343.4 , NM_033343.3
Accession Version	NM_033343.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139141.23, BX954266.1, AF179849.1 and BC011759.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_033343.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.111766.1, AF179849.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263726.4/ ENSP00000263726.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGCAGA GTGCGACTGT CCCCGCGGAA GGGGCTGTCA AGGGGCTCCC GGAGATGCTA 
GGTGTGCCGA TGCAACAGAT TCCCCAGTGC GCTGGCTGCA ACCAGCACAT CCTGGACAAG 
TTCATCCTGA AGGTCCTGGA CAGACACTGG CACAGCTCCT GCCTCAAGTG TGCAGACTGC 
CAGATGCAGC TGGCGGACAG GTGCTTCTCC AGGGCTGGGA GCGTCTACTG CAAGGAGGAC 
TTCTTCAAGC GCTTCGGCAC AAAATGCACG GCCTGCCAGC AGGGTATCCC CCCAACCCAG 
GTGGTCCGCA AGGCCCAGGA CTTTGTCTAC CACCTGCACT GCTTTGCTTG CATCATCTGC 
AACCGGCAGC TGGCCACGGG GGACGAATTC TACCTCATGG AGGACGGGCG GCTGGTGTGC 
AAGGAAGACT ACGAGACAGC CAAGCAGAAC GATGACTCAG AGGCTGGAGC TAAGCGGCCC 
CGGACCACCA TCACAGCCAA GCAGCTGGAG ACATTAAAGA ATGCATACAA GAACTCCCCC 
AAGCCTGCCC GGCACGTGAG GGAGCAGCTG TCCTCAGAGA CAGGCCTGGA CATGAGGGTC 
GTACAGGTTT GGTTTCAGAA CAGAAGGGCC AAAGAGAAAC GCCTGAAGAA GGATGCAGGG 
CGGCACCGCT GGGGGCAGTT CTATAAGAGC GTCAAGAGGA GCCGGGGCAG CAGCAAGCAG 
GAGAAGGAGA GCTCTGCAGA GGACTGTGGG GTTAGTGACA GTGAGCTGAG CTTCCGAGAG 
GATCAAATTC TCTCAGAACT TGGCCACACC AATAGGATTT ATGGCAACGT GGGGGACGTT 
ACAGGCGGAC AGTTAATGAA TGGGAGCTTC TCCATGGACG GGACAGGACA ATCCTATCAG 
GACTTGAGGG ATGGGAGCCC CTATGGAATC CCCCAGTCTC CATCCTCCAT ATCGTCCCTG 
CCATCCCACG CTCCTTTGCT CAATGGGCTG GATTACACGG TGGACAGTAA TTTGGGCATC 
ATTGCGCATG CAGGGCAGGG AGTAAGCCAG ACGCTGAGAG CCATGGCTGG GGGACCCACC 
TCTGACATCT CCACAGGAAG CAGTGTAGGC TATCCCGACT TTCCAACTAG CCCAGGCTCT 
TGGCTCGATG AAATGGATCA TCCTCCTTTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_203129.1
CDS	267..1439
Translation	MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF

Target ORF information:

RefSeq Version	NM_033343.4
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 4 (LHX4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033343.4

ORF Insert Sequence:

ATGATGCAGA GTGCGACTGT CCCCGCGGAA GGGGCTGTCA AGGGGCTCCC GGAGATGCTA 
GGTGTGCCGA TGCAACAGAT TCCCCAGTGC GCTGGCTGCA ACCAGCACAT CCTGGACAAG 
TTCATCCTGA AGGTCCTGGA CAGACACTGG CACAGCTCCT GCCTCAAGTG TGCAGACTGC 
CAGATGCAGC TGGCGGACAG GTGCTTCTCC AGGGCTGGGA GCGTCTACTG CAAGGAGGAC 
TTCTTCAAGC GCTTCGGCAC AAAATGCACG GCCTGCCAGC AGGGTATCCC CCCAACCCAG 
GTGGTCCGCA AGGCCCAGGA CTTTGTCTAC CACCTGCACT GCTTTGCTTG CATCATCTGC 
AACCGGCAGC TGGCCACGGG GGACGAATTC TACCTCATGG AGGACGGGCG GCTGGTGTGC 
AAGGAAGACT ACGAGACAGC CAAGCAGAAC GATGACTCAG AGGCTGGAGC TAAGCGGCCC 
CGGACCACCA TCACAGCCAA GCAGCTGGAG ACATTAAAGA ATGCATACAA GAACTCCCCC 
AAGCCTGCCC GGCACGTGAG GGAGCAGCTG TCCTCAGAGA CAGGCCTGGA CATGAGGGTC 
GTACAGGTTT GGTTTCAGAA CAGAAGGGCC AAAGAGAAAC GCCTGAAGAA GGATGCAGGG 
CGGCACCGCT GGGGGCAGTT CTATAAGAGC GTCAAGAGGA GCCGGGGCAG CAGCAAGCAG 
GAGAAGGAGA GCTCTGCAGA GGACTGTGGG GTTAGTGACA GTGAGCTGAG CTTCCGAGAG 
GATCAAATTC TCTCAGAACT TGGCCACACC AATAGGATTT ATGGCAACGT GGGGGACGTT 
ACAGGCGGAC AGTTAATGAA TGGGAGCTTC TCCATGGACG GGACAGGACA ATCCTATCAG 
GACTTGAGGG ATGGGAGCCC CTATGGAATC CCCCAGTCTC CATCCTCCAT ATCGTCCCTG 
CCATCCCACG CTCCTTTGCT CAATGGGCTG GATTACACGG TGGACAGTAA TTTGGGCATC 
ATTGCGCATG CAGGGCAGGG AGTAAGCCAG ACGCTGAGAG CCATGGCTGG GGGACCCACC 
TCTGACATCT CCACAGGAAG CAGTGTAGGC TATCCCGACT TTCCAACTAG CCCAGGCTCT 
TGGCTCGATG AAATGGATCA TCCTCCTTTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX4 ( NM_033343.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_203129.1 Homo sapiens LIM homeobox 4 (LHX4), mRNA.

Price & Availability↑

CloneID	OHu22868
Clone ID Related Accession (Same CDS sequence)	NM_033343.4 , NM_033343.3
Accession Version	NM_033343.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX954266.1, AF179849.1, AL139141.23 and BC011759.2. This sequence is a reference standard in the RefSeqGene project. On Dec 14, 2010 this sequence version replaced NM_033343.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011759.2, SRR1660807.111766.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGCAGA GTGCGACTGT CCCCGCGGAA GGGGCTGTCA AGGGGCTCCC GGAGATGCTA 
GGTGTGCCGA TGCAACAGAT TCCCCAGTGC GCTGGCTGCA ACCAGCACAT CCTGGACAAG 
TTCATCCTGA AGGTCCTGGA CAGACACTGG CACAGCTCCT GCCTCAAGTG TGCAGACTGC 
CAGATGCAGC TGGCGGACAG GTGCTTCTCC AGGGCTGGGA GCGTCTACTG CAAGGAGGAC 
TTCTTCAAGC GCTTCGGCAC AAAATGCACG GCCTGCCAGC AGGGTATCCC CCCAACCCAG 
GTGGTCCGCA AGGCCCAGGA CTTTGTCTAC CACCTGCACT GCTTTGCTTG CATCATCTGC 
AACCGGCAGC TGGCCACGGG GGACGAATTC TACCTCATGG AGGACGGGCG GCTGGTGTGC 
AAGGAAGACT ACGAGACAGC CAAGCAGAAC GATGACTCAG AGGCTGGAGC TAAGCGGCCC 
CGGACCACCA TCACAGCCAA GCAGCTGGAG ACATTAAAGA ATGCATACAA GAACTCCCCC 
AAGCCTGCCC GGCACGTGAG GGAGCAGCTG TCCTCAGAGA CAGGCCTGGA CATGAGGGTC 
GTACAGGTTT GGTTTCAGAA CAGAAGGGCC AAAGAGAAAC GCCTGAAGAA GGATGCAGGG 
CGGCACCGCT GGGGGCAGTT CTATAAGAGC GTCAAGAGGA GCCGGGGCAG CAGCAAGCAG 
GAGAAGGAGA GCTCTGCAGA GGACTGTGGG GTTAGTGACA GTGAGCTGAG CTTCCGAGAG 
GATCAAATTC TCTCAGAACT TGGCCACACC AATAGGATTT ATGGCAACGT GGGGGACGTT 
ACAGGCGGAC AGTTAATGAA TGGGAGCTTC TCCATGGACG GGACAGGACA ATCCTATCAG 
GACTTGAGGG ATGGGAGCCC CTATGGAATC CCCCAGTCTC CATCCTCCAT ATCGTCCCTG 
CCATCCCACG CTCCTTTGCT CAATGGGCTG GATTACACGG TGGACAGTAA TTTGGGCATC 
ATTGCGCATG CAGGGCAGGG AGTAAGCCAG ACGCTGAGAG CCATGGCTGG GGGACCCACC 
TCTGACATCT CCACAGGAAG CAGTGTAGGC TATCCCGACT TTCCAACTAG CCCAGGCTCT 
TGGCTCGATG AAATGGATCA TCCTCCTTTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_203129.1
CDS	233..1405
Translation	MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF

Target ORF information:

RefSeq Version	NM_033343.3
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 4 (LHX4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033343.3

ORF Insert Sequence:

ATGATGCAGA GTGCGACTGT CCCCGCGGAA GGGGCTGTCA AGGGGCTCCC GGAGATGCTA 
GGTGTGCCGA TGCAACAGAT TCCCCAGTGC GCTGGCTGCA ACCAGCACAT CCTGGACAAG 
TTCATCCTGA AGGTCCTGGA CAGACACTGG CACAGCTCCT GCCTCAAGTG TGCAGACTGC 
CAGATGCAGC TGGCGGACAG GTGCTTCTCC AGGGCTGGGA GCGTCTACTG CAAGGAGGAC 
TTCTTCAAGC GCTTCGGCAC AAAATGCACG GCCTGCCAGC AGGGTATCCC CCCAACCCAG 
GTGGTCCGCA AGGCCCAGGA CTTTGTCTAC CACCTGCACT GCTTTGCTTG CATCATCTGC 
AACCGGCAGC TGGCCACGGG GGACGAATTC TACCTCATGG AGGACGGGCG GCTGGTGTGC 
AAGGAAGACT ACGAGACAGC CAAGCAGAAC GATGACTCAG AGGCTGGAGC TAAGCGGCCC 
CGGACCACCA TCACAGCCAA GCAGCTGGAG ACATTAAAGA ATGCATACAA GAACTCCCCC 
AAGCCTGCCC GGCACGTGAG GGAGCAGCTG TCCTCAGAGA CAGGCCTGGA CATGAGGGTC 
GTACAGGTTT GGTTTCAGAA CAGAAGGGCC AAAGAGAAAC GCCTGAAGAA GGATGCAGGG 
CGGCACCGCT GGGGGCAGTT CTATAAGAGC GTCAAGAGGA GCCGGGGCAG CAGCAAGCAG 
GAGAAGGAGA GCTCTGCAGA GGACTGTGGG GTTAGTGACA GTGAGCTGAG CTTCCGAGAG 
GATCAAATTC TCTCAGAACT TGGCCACACC AATAGGATTT ATGGCAACGT GGGGGACGTT 
ACAGGCGGAC AGTTAATGAA TGGGAGCTTC TCCATGGACG GGACAGGACA ATCCTATCAG 
GACTTGAGGG ATGGGAGCCC CTATGGAATC CCCCAGTCTC CATCCTCCAT ATCGTCCCTG 
CCATCCCACG CTCCTTTGCT CAATGGGCTG GATTACACGG TGGACAGTAA TTTGGGCATC 
ATTGCGCATG CAGGGCAGGG AGTAAGCCAG ACGCTGAGAG CCATGGCTGG GGGACCCACC 
TCTGACATCT CCACAGGAAG CAGTGTAGGC TATCCCGACT TTCCAACTAG CCCAGGCTCT 
TGGCTCGATG AAATGGATCA TCCTCCTTTT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science (New York, N.Y.)356(6337)(2017 05)
Yin Y,Morgunova E,Jolma A,Kaasinen E,Sahu B,Khund-Sayeed S,Das PK,Kivioja T,Dave K,Zhong F,Nitta KR,Taipale M,Popov A,Ginno PA,Domcke S,Yan J,Schübeler D,Vinson C,Taipale J

Contribution of LHX4 Mutations to Pituitary Deficits in a Cohort of 417 Unrelated Patients.
The Journal of clinical endocrinology and metabolism102(1)290-301(2017 01)
Cohen E,Maghnie M,Collot N,Leger J,Dastot F,Polak M,Rose S,Touraine P,Duquesnoy P,Tauber M,Copin B,Bertrand AM,Brioude F,Larizza D,Edouard T,González Briceño L,Netchine I,Oliver-Petit I,Sobrier ML,Amselem S,Legendre M

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Taşan M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barabási AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
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LHX4 cDNA ORF clone, Homo sapiens(human)

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