| Gene Symbol | ATCAY |
| Entrez Gene ID | 85300 |
| Full Name | ATCAY, caytaxin |
| Synonyms | BNIP-H,CLAC |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | Ataxia, cerebellar, Cayman type, 601238 (3) |
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ATCAY cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following ATCAY gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATCAY cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu22234 Clone ID Related Accession (Same CDS sequence) NM_033064.5 , NM_033064.4 Accession Version NM_033064.5 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1116bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1561392000000 Organism Homo sapiens(human) Product caytaxin Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011488.7. On Nov 23, 2018 this sequence version replaced NM_033064.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK027889.1, AB058775.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000450849.7/ ENSP00000390941.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.
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481
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601
661
721
781
841
901
961
1021
1081ATGGGGACCA CCGAAGCCAC GCTCCGGATG GAAAACGTGG ACGTGAAGGA GGAATGGCAG
GACGAAGATC TTCCCAGGCC ACTCCCAGAA GAGACGGGGG TGGAACTGCT TGGCAGCCCG
GTGGAAGACA CATCCTCTCC TCCCAACACG CTAAATTTCA ACGGAGCGCA TCGTAAGAGG
AAGACGCTGG TGGCCCCAGA GATCAACATT TCTCTGGATC AGAGTGAGGG GTCCCTGCTG
TCCGATGACT TCTTGGATAC CCCTGATGAC CTGGATATTA ACGTGGATGA CATCGAGACC
CCCGATGAGA CCGACTCGCT GGAGTTCCTG GGGAATGGCA ACGAACTGGA GTGGGAAGAC
GACACCCCCG TGGCCACCGC CAAGAACATG CCCGGGGACA GCGCGGATCT ATTTGGGGAC
GGCACGACGG AGGACGGCAG CGCCGCCAAC GGGCGCCTGT GGCGGACAGT GATCATCGGG
GAGCAAGAGC ACCGTATAGA CCTGCACATG ATCCGGCCTT ACATGAAAGT GGTCACCCAC
GGAGGGTACT ACGGCGAAGG CCTCAACGCC ATCATCGTCT TCGCAGCCTG CTTCCTTCCA
GACAGCAGCC TCCCCGACTA CCACTACATC ATGGAGAACC TCTTCCTGTA CGTCATCAGC
AGCTTAGAGC TCCTGGTGGC TGAGGACTAC ATGATCGTGT ACCTGAACGG TGCCACGCCC
CGGCGGAGGA TGCCTGGAAT CGGCTGGCTG AAGAAGTGCT ACCAGATGAT CGACCGGAGG
TTGCGGAAAA ACCTGAAGTC CTTGATCATC GTCCACCCCT CGTGGTTCAT TCGGACTGTG
CTGGCCATCT CTCGCCCTTT CATCAGCGTC AAGTTCATCA ACAAGATCCA GTACGTGCAC
AGCTTGGAAG ACCTGGAGCA ACTCATCCCT ATGGAACACG TCCAGATCCC AGACTGCGTC
CTGCAATACG AAGAGGAAAG ACTGAAGGCC AGGAGGGAGA GCGCGAGGCC CCAGCCGGAG
TTTGTGCTGC CCAGGTCTGA AGAGAAGCCA GAGGTGGCAC CAGTGGAAAA CAGGTCTGCT
CTGGTCTCAG AAGATCAGGA AACAAGCATG TCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_149053.1 CDS 366..1481 Translation 
Target ORF information:
RefSeq Version NM_033064.5 Organism Homo sapiens(human) Definition Homo sapiens ATCAY kinesin light chain interacting caytaxin (ATCAY), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_033064.5
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGGGGACCA CCGAAGCCAC GCTCCGGATG GAAAACGTGG ACGTGAAGGA GGAATGGCAG
GACGAAGATC TTCCCAGGCC ACTCCCAGAA GAGACGGGGG TGGAACTGCT TGGCAGCCCG
GTGGAAGACA CATCCTCTCC TCCCAACACG CTAAATTTCA ACGGAGCGCA TCGTAAGAGG
AAGACGCTGG TGGCCCCAGA GATCAACATT TCTCTGGATC AGAGTGAGGG GTCCCTGCTG
TCCGATGACT TCTTGGATAC CCCTGATGAC CTGGATATTA ACGTGGATGA CATCGAGACC
CCCGATGAGA CCGACTCGCT GGAGTTCCTG GGGAATGGCA ACGAACTGGA GTGGGAAGAC
GACACCCCCG TGGCCACCGC CAAGAACATG CCCGGGGACA GCGCGGATCT ATTTGGGGAC
GGCACGACGG AGGACGGCAG CGCCGCCAAC GGGCGCCTGT GGCGGACAGT GATCATCGGG
GAGCAAGAGC ACCGTATAGA CCTGCACATG ATCCGGCCTT ACATGAAAGT GGTCACCCAC
GGAGGGTACT ACGGCGAAGG CCTCAACGCC ATCATCGTCT TCGCAGCCTG CTTCCTTCCA
GACAGCAGCC TCCCCGACTA CCACTACATC ATGGAGAACC TCTTCCTGTA CGTCATCAGC
AGCTTAGAGC TCCTGGTGGC TGAGGACTAC ATGATCGTGT ACCTGAACGG TGCCACGCCC
CGGCGGAGGA TGCCTGGAAT CGGCTGGCTG AAGAAGTGCT ACCAGATGAT CGACCGGAGG
TTGCGGAAAA ACCTGAAGTC CTTGATCATC GTCCACCCCT CGTGGTTCAT TCGGACTGTG
CTGGCCATCT CTCGCCCTTT CATCAGCGTC AAGTTCATCA ACAAGATCCA GTACGTGCAC
AGCTTGGAAG ACCTGGAGCA ACTCATCCCT ATGGAACACG TCCAGATCCC AGACTGCGTC
CTGCAATACG AAGAGGAAAG ACTGAAGGCC AGGAGGGAGA GCGCGAGGCC CCAGCCGGAG
TTTGTGCTGC CCAGGTCTGA AGAGAAGCCA GAGGTGGCAC CAGTGGAAAA CAGGTCTGCT
CTGGTCTCAG AAGATCAGGA AACAAGCATG TCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu22234 Clone ID Related Accession (Same CDS sequence) NM_033064.5 , NM_033064.4 Accession Version NM_033064.4 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1116bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1506787200000 Organism Homo sapiens(human) Product caytaxin Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA778097.1, BC026217.1, AB058775.1, AC011488.7 and BF516378.1. This sequence is a reference standard in the RefSeqGene project. On May 29, 2008 this sequence version replaced NM_033064.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.221684.1, SRR1803613.25653.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGGGGACCA CCGAAGCCAC GCTCCGGATG GAAAACGTGG ACGTGAAGGA GGAATGGCAG
GACGAAGATC TTCCCAGGCC ACTCCCAGAA GAGACGGGGG TGGAACTGCT TGGCAGCCCG
GTGGAAGACA CATCCTCTCC TCCCAACACG CTAAATTTCA ACGGAGCGCA TCGTAAGAGG
AAGACGCTGG TGGCCCCAGA GATCAACATT TCTCTGGATC AGAGTGAGGG GTCCCTGCTG
TCCGATGACT TCTTGGATAC CCCTGATGAC CTGGATATTA ACGTGGATGA CATCGAGACC
CCCGATGAGA CCGACTCGCT GGAGTTCCTG GGGAATGGCA ACGAACTGGA GTGGGAAGAC
GACACCCCCG TGGCCACCGC CAAGAACATG CCCGGGGACA GCGCGGATCT ATTTGGGGAC
GGCACGACGG AGGACGGCAG CGCCGCCAAC GGGCGCCTGT GGCGGACAGT GATCATCGGG
GAGCAAGAGC ACCGTATAGA CCTGCACATG ATCCGGCCTT ACATGAAAGT GGTCACCCAC
GGAGGGTACT ACGGCGAAGG CCTCAACGCC ATCATCGTCT TCGCAGCCTG CTTCCTTCCA
GACAGCAGCC TCCCCGACTA CCACTACATC ATGGAGAACC TCTTCCTGTA CGTCATCAGC
AGCTTAGAGC TCCTGGTGGC TGAGGACTAC ATGATCGTGT ACCTGAACGG TGCCACGCCC
CGGCGGAGGA TGCCTGGAAT CGGCTGGCTG AAGAAGTGCT ACCAGATGAT CGACCGGAGG
TTGCGGAAAA ACCTGAAGTC CTTGATCATC GTCCACCCCT CGTGGTTCAT TCGGACTGTG
CTGGCCATCT CTCGCCCTTT CATCAGCGTC AAGTTCATCA ACAAGATCCA GTACGTGCAC
AGCTTGGAAG ACCTGGAGCA ACTCATCCCT ATGGAACACG TCCAGATCCC AGACTGCGTC
CTGCAATACG AAGAGGAAAG ACTGAAGGCC AGGAGGGAGA GCGCGAGGCC CCAGCCGGAG
TTTGTGCTGC CCAGGTCTGA AGAGAAGCCA GAGGTGGCAC CAGTGGAAAA CAGGTCTGCT
CTGGTCTCAG AAGATCAGGA AACAAGCATG TCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_149053.1 CDS 431..1546 Translation
Target ORF information:
RefSeq Version NM_033064.4 Organism Homo sapiens(human) Definition Homo sapiens ATCAY, caytaxin (ATCAY), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_033064.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGGGGACCA CCGAAGCCAC GCTCCGGATG GAAAACGTGG ACGTGAAGGA GGAATGGCAG
GACGAAGATC TTCCCAGGCC ACTCCCAGAA GAGACGGGGG TGGAACTGCT TGGCAGCCCG
GTGGAAGACA CATCCTCTCC TCCCAACACG CTAAATTTCA ACGGAGCGCA TCGTAAGAGG
AAGACGCTGG TGGCCCCAGA GATCAACATT TCTCTGGATC AGAGTGAGGG GTCCCTGCTG
TCCGATGACT TCTTGGATAC CCCTGATGAC CTGGATATTA ACGTGGATGA CATCGAGACC
CCCGATGAGA CCGACTCGCT GGAGTTCCTG GGGAATGGCA ACGAACTGGA GTGGGAAGAC
GACACCCCCG TGGCCACCGC CAAGAACATG CCCGGGGACA GCGCGGATCT ATTTGGGGAC
GGCACGACGG AGGACGGCAG CGCCGCCAAC GGGCGCCTGT GGCGGACAGT GATCATCGGG
GAGCAAGAGC ACCGTATAGA CCTGCACATG ATCCGGCCTT ACATGAAAGT GGTCACCCAC
GGAGGGTACT ACGGCGAAGG CCTCAACGCC ATCATCGTCT TCGCAGCCTG CTTCCTTCCA
GACAGCAGCC TCCCCGACTA CCACTACATC ATGGAGAACC TCTTCCTGTA CGTCATCAGC
AGCTTAGAGC TCCTGGTGGC TGAGGACTAC ATGATCGTGT ACCTGAACGG TGCCACGCCC
CGGCGGAGGA TGCCTGGAAT CGGCTGGCTG AAGAAGTGCT ACCAGATGAT CGACCGGAGG
TTGCGGAAAA ACCTGAAGTC CTTGATCATC GTCCACCCCT CGTGGTTCAT TCGGACTGTG
CTGGCCATCT CTCGCCCTTT CATCAGCGTC AAGTTCATCA ACAAGATCCA GTACGTGCAC
AGCTTGGAAG ACCTGGAGCA ACTCATCCCT ATGGAACACG TCCAGATCCC AGACTGCGTC
CTGCAATACG AAGAGGAAAG ACTGAAGGCC AGGAGGGAGA GCGCGAGGCC CCAGCCGGAG
TTTGTGCTGC CCAGGTCTGA AGAGAAGCCA GAGGTGGCAC CAGTGGAAAA CAGGTCTGCT
CTGGTCTCAG AAGATCAGGA AACAAGCATG TCCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Novel homozygous variants in ATCAY, MCOLN1, and SACS in complex neurological disorders.
Parkinsonism & related disorders5191-95(2018 06)
Manzoor H,Brüggemann N,Hussain HMJ,Bäumer T,Hinrichs F,Wajid M,Münchau A,Naz S,Lohmann K
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M
Expression of Caytaxin protein in Cayman Ataxia mouse models correlates with phenotype severity.
PloS one7(11)e50570(2012)
Sikora KM,Nosavanh LM,Kantheti P,Burmeister M,Hortsch M
A genome-wide association study of aging.
Neurobiology of aging32(11)2109.e15-28(2011 Nov)
Walter S,Atzmon G,Demerath EW,Garcia ME,Kaplan RC,Kumari M,Lunetta KL,Milaneschi Y,Tanaka T,Tranah GJ,Völker U,Yu L,Arnold A,Benjamin EJ,Biffar R,Buchman AS,Boerwinkle E,Couper D,De Jager PL,Evans DA,Harris TB,Hoffmann W,Hofman A,Karasik D,Kiel DP,Kocher T,Kuningas M,Launer LJ,Lohman KK,Lutsey PL,Mackenbach J,Marciante K,Psaty BM,Reiman EM,Rotter JI,Seshadri S,Shardell MD,Smith AV,van Duijn C,Walston J,Zillikens MC,Bandinelli S,Baumeister SE,Bennett DA,Ferrucci L,Gudnason V,Kivimaki M,Liu Y,Murabito JM,Newman AB,Tiemeier H,Franceschini N
Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains.
Journal of cell science122(Pt 22)4177-85(2009 Nov)
Aoyama T,Hata S,Nakao T,Tanigawa Y,Oka C,Kawaichi M
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