KIF2B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KIF2B
Entrez Gene ID	84643
Full Name	kinesin family member 2B
General protein information	Preferred Names kinesin family member 2B Names kinesin-like protein KIF2B kinesin protein testis tissue sperm-binding protein Li 82P
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q22
Disorder MIM:	615142

mRNA and Protein(s)

mRNA	Protein	Name
NM_032559.5	NP_115948.4	kinesin-like protein KIF2B
NM_032559.4	NP_115948.4	kinesin-like protein KIF2B

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Kif2b	NP_001005874.2
Pan troglodytes (chimpanzee)	KIF2B	XP_001171578.1
Bos taurus (cattle)	KIF2B	NP_001094651.1
Macaca mulatta (Rhesus monkey)	KIF2B	XP_001102312.2
Mus musculus (house mouse)	Kif2b	NP_082823.1
Homo sapiens (human)	KIF2B	NP_115948.4
Canis lupus familiaris (dog)	KIF2B	XP_005625044.1

Gene Ontology
Bibliography

Related articles in PubMed

Phosphorylation of SKAP by GSK3β ensures chromosome segregation by a temporal inhibition of Kif2b activity.
Qin B, Cao D, Wu H, Mo F, Shao H, Chu J, Powell M, Aikhionbare F, Wang D, Fu C, He P, Pan W, Wang W, Liu X, Yao X
Scientific reports638791(2016 12)

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
Watanabe T, Kakeno M, Matsui T, Sugiyama I, Arimura N, Matsuzawa K, Shirahige A, Ishidate F, Nishioka T, Taya S, Hoshino M, Kaibuchi K
The Journal of cell biology210(5)737-51(2015 Aug)

Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK.
Shrestha RL, Draviam VM
Current biology : CB23(16)1514-26(2013 Aug)

The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.
Welburn JP, Cheeseman IM
Molecular biology of the cell23(24)4786-95(2012 Dec)

Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
Hood EA, Kettenbach AN, Gerber SA, Compton DA
Molecular biology of the cell23(12)2264-74(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KIF2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KIF2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30761	NM_032559.5 Latest version!	Homo sapiens kinesin family member 2B (KIF2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu30761	NM_032559.4	Homo sapiens kinesin family member 2B (KIF2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KIF2B ( NM_032559.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_115948.4 Homo sapiens kinesin family member 2B (KIF2B), mRNA.

Price & Availability↑

CloneID	OHu30761
Clone ID Related Accession (Same CDS sequence)	NM_032559.5 , NM_032559.4
Accession Version	NM_032559.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF2B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC019315.9 and AF333335.2. On May 17, 2019 this sequence version replaced NM_032559.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC033802.1, SRR5189667.121511.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000268919.6/ ENSP00000268919.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCC AGTTCTGCCT CCCTGAATCC CCATGTCTCT CGCCCCTGAA ACCCTTGAAG 
CCACATTTCG GAGACATCCA AGAGGGCATC TACGTGGCGA TCCAGCGCAG TGACAAGCGG 
ATCCACCTCG CTGTGGTCAC GGAGATCAAC AGAGAAAACT ATTGGGTCAC GGTAGAGTGG 
GTGGAGAAAG CAGTCAAAAA AGGCAAGAAG ATTGACCTGG AGACCATACT CCTGCTGAAT 
CCAGCTCTGG ACTCTGCTGA ACACCCCATG CCGCCCCCGC CCTTATCCCC CTTGGCTCTG 
GCGCCCTCTT CGGCCATCAG GGACCAGCGT ACCGCCACGA AATGGGTTGC GATGATCCCC 
CAGAAAAACC AAACAGCCTC AGGGGACAGC CTGGATGTGA GGGTCCCCAG CAAACCTTGT 
CTGATGAAGC AGAAAAAGTC TCCCTGCCTC TGGGAAATCC AGAAACTGCA GGAGCAGCGG 
GAAAAGCGCA GGCGGCTGCA GCAGGAGATC CGAGCTAGAC GCGCCCTCGA TGTCAATACC 
AGAAACCCCA ACTACGAAAT CATGCACATG ATCGAAGAGT ATCGCAGGCA CCTGGACAGC 
AGCAAGATCT CAGTCCTGGA GCCCCCGCAA GAACATCGCA TCTGCGTCTG CGTGAGGAAG 
CGGCCTCTCA ACCAGCGAGA GACAACCTTA AAGGACCTGG ATATCATCAC CGTCCCCTCG 
GACAATGTGG TTATGGTGCA TGAGTCCAAG CAAAAGGTGG ACCTCACTCG CTACCTGCAG 
AACCAGACCT TCTGCTTCGA CCATGCCTTC GATGACAAAG CCTCCAACGA GTTGGTGTAC 
CAGTTCACCG CCCAGCCACT GGTGGAGTCC ATCTTCCGCA AGGGCATGGC CACCTGCTTT 
GCCTATGGGC AGACGGGAAG TGGGAAGACG TACACCATGG GTGGAGACTT TTCAGGAACG 
GCCCAAGATT GTTCTAAGGG CATTTATGCT CTGGTGGCAC AGGATGTCTT TCTCCTGCTC 
AGAAACTCCA CATATGAGAA GCTGGACCTC AAAGTCTATG GGACATTTTT TGAGATTTAT 
GGGGGCAAGG TGTATGATTT GTTGAACTGG AAGAAGAAGC TGCAAGTCCT TGAGGATGGC 
AATCAGCAAA TCCAAGTGGT CGGGCTGCAG GAGAAAGAGG TGTGTTGTGT GGAGGAAGTG 
CTGAACCTGG TGGAAATAGG GAATAGCTGT CGGACTTCCA GGCAAACACC TGTCAACGCT 
CACTCATCCA GGAGCCATGC AGTGTTCCAG ATCATCCTGA AGTCAGGACG GATAATGCAT 
GGCAAGTTTT CCCTCGTTGA TTTAGCTGGG AATGAAAGAG GAGCAGATAC AACCAAGGCC 
AGCCGGAAAA GGCAGCTGGA AGGGGCAGAG ATTAACAAGA GTCTTCTAGC CCTCAAAGAA 
TGTATTCTGG CTTTGGGTCA GAACAAGCCT CACACCCCAT TCAGAGCCAG CAAACTCACA 
CTGGTGCTCC GGGACTCCTT TATAGGCCAG AACTCCTCCA CTTGCATGAT TGCTACCATC 
TCTCCGGGGA TGACCTCTTG TGAAAACACT CTCAACACTT TAAGATATGC AAACAGAGTA 
AAAAAATTAA ATGTAGATGT AAGGCCCTAC CATCGTGGCC ACTATCCGAT TGGACATGAG 
GCACCAAGGA TGTTAAAAAG TCACATCGGA AATTCAGAAA TGTCCCTTCA GAGGGATGAA 
TTTATTAAAA TACCTTATGT ACAGAGTGAG GAGCAGAAAG AGATTGAAGA GGTTGAAACA 
TTACCCACTC TGTTAGGGAA GGATACCACA ATTTCAGGGA AGGGATCTAG CCAATGGCTG 
GAAAACATCC AGGAGAGAGC TGGTGGAGTA CACCATGATA TTGATTTTTG CATTGCCCGG 
TCTTTGTCCA TTTTGGAGCA GAAAATTGAT GCTCTGACCG AGATCCAAAA GAAACTGAAA 
TTATTACTAG CTGACCTCCA CGTGAAGAGC AAGGTAGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115948.4
CDS	108..2129
Translation	MASQFCLPESPCLSPLKPLKPHFGDIQEGIYVAIQRSDKRIHLAVVTEINRENYWVTVEWVEKAVKKGKKIDLETILLLNPALDSAEHPMPPPPLSPLALAPSSAIRDQRTATKWVAMIPQKNQTASGDSLDVRVPSKPCLMKQKKSPCLWEIQKLQEQREKRRRLQQEIRARRALDVNTRNPNYEIMHMIEEYRRHLDSSKISVLEPPQEHRICVCVRKRPLNQRETTLKDLDIITVPSDNVVMVHESKQKVDLTRYLQNQTFCFDHAFDDKASNELVYQFTAQPLVESIFRKGMATCFAYGQTGSGKTYTMGGDFSGTAQDCSKGIYALVAQDVFLLLRNSTYEKLDLKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGNQQIQVVGLQEKEVCCVEEVLNLVEIGNSCRTSRQTPVNAHSSRSHAVFQIILKSGRIMHGKFSLVDLAGNERGADTTKASRKRQLEGAEINKSLLALKECILALGQNKPHTPFRASKLTLVLRDSFIGQNSSTCMIATISPGMTSCENTLNTLRYANRVKKLNVDVRPYHRGHYPIGHEAPRMLKSHIGNSEMSLQRDEFIKIPYVQSEEQKEIEEVETLPTLLGKDTTISGKGSSQWLENIQERAGGVHHDIDFCIARSLSILEQKIDALTEIQKKLKLLLADLHVKSKVE

Target ORF information:

RefSeq Version	NM_032559.5
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 2B (KIF2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032559.5

ORF Insert Sequence:

ATGGCCAGCC AGTTCTGCCT CCCTGAATCC CCATGTCTCT CGCCCCTGAA ACCCTTGAAG 
CCACATTTCG GAGACATCCA AGAGGGCATC TACGTGGCGA TCCAGCGCAG TGACAAGCGG 
ATCCACCTCG CTGTGGTCAC GGAGATCAAC AGAGAAAACT ATTGGGTCAC GGTAGAGTGG 
GTGGAGAAAG CAGTCAAAAA AGGCAAGAAG ATTGACCTGG AGACCATACT CCTGCTGAAT 
CCAGCTCTGG ACTCTGCTGA ACACCCCATG CCGCCCCCGC CCTTATCCCC CTTGGCTCTG 
GCGCCCTCTT CGGCCATCAG GGACCAGCGT ACCGCCACGA AATGGGTTGC GATGATCCCC 
CAGAAAAACC AAACAGCCTC AGGGGACAGC CTGGATGTGA GGGTCCCCAG CAAACCTTGT 
CTGATGAAGC AGAAAAAGTC TCCCTGCCTC TGGGAAATCC AGAAACTGCA GGAGCAGCGG 
GAAAAGCGCA GGCGGCTGCA GCAGGAGATC CGAGCTAGAC GCGCCCTCGA TGTCAATACC 
AGAAACCCCA ACTACGAAAT CATGCACATG ATCGAAGAGT ATCGCAGGCA CCTGGACAGC 
AGCAAGATCT CAGTCCTGGA GCCCCCGCAA GAACATCGCA TCTGCGTCTG CGTGAGGAAG 
CGGCCTCTCA ACCAGCGAGA GACAACCTTA AAGGACCTGG ATATCATCAC CGTCCCCTCG 
GACAATGTGG TTATGGTGCA TGAGTCCAAG CAAAAGGTGG ACCTCACTCG CTACCTGCAG 
AACCAGACCT TCTGCTTCGA CCATGCCTTC GATGACAAAG CCTCCAACGA GTTGGTGTAC 
CAGTTCACCG CCCAGCCACT GGTGGAGTCC ATCTTCCGCA AGGGCATGGC CACCTGCTTT 
GCCTATGGGC AGACGGGAAG TGGGAAGACG TACACCATGG GTGGAGACTT TTCAGGAACG 
GCCCAAGATT GTTCTAAGGG CATTTATGCT CTGGTGGCAC AGGATGTCTT TCTCCTGCTC 
AGAAACTCCA CATATGAGAA GCTGGACCTC AAAGTCTATG GGACATTTTT TGAGATTTAT 
GGGGGCAAGG TGTATGATTT GTTGAACTGG AAGAAGAAGC TGCAAGTCCT TGAGGATGGC 
AATCAGCAAA TCCAAGTGGT CGGGCTGCAG GAGAAAGAGG TGTGTTGTGT GGAGGAAGTG 
CTGAACCTGG TGGAAATAGG GAATAGCTGT CGGACTTCCA GGCAAACACC TGTCAACGCT 
CACTCATCCA GGAGCCATGC AGTGTTCCAG ATCATCCTGA AGTCAGGACG GATAATGCAT 
GGCAAGTTTT CCCTCGTTGA TTTAGCTGGG AATGAAAGAG GAGCAGATAC AACCAAGGCC 
AGCCGGAAAA GGCAGCTGGA AGGGGCAGAG ATTAACAAGA GTCTTCTAGC CCTCAAAGAA 
TGTATTCTGG CTTTGGGTCA GAACAAGCCT CACACCCCAT TCAGAGCCAG CAAACTCACA 
CTGGTGCTCC GGGACTCCTT TATAGGCCAG AACTCCTCCA CTTGCATGAT TGCTACCATC 
TCTCCGGGGA TGACCTCTTG TGAAAACACT CTCAACACTT TAAGATATGC AAACAGAGTA 
AAAAAATTAA ATGTAGATGT AAGGCCCTAC CATCGTGGCC ACTATCCGAT TGGACATGAG 
GCACCAAGGA TGTTAAAAAG TCACATCGGA AATTCAGAAA TGTCCCTTCA GAGGGATGAA 
TTTATTAAAA TACCTTATGT ACAGAGTGAG GAGCAGAAAG AGATTGAAGA GGTTGAAACA 
TTACCCACTC TGTTAGGGAA GGATACCACA ATTTCAGGGA AGGGATCTAG CCAATGGCTG 
GAAAACATCC AGGAGAGAGC TGGTGGAGTA CACCATGATA TTGATTTTTG CATTGCCCGG 
TCTTTGTCCA TTTTGGAGCA GAAAATTGAT GCTCTGACCG AGATCCAAAA GAAACTGAAA 
TTATTACTAG CTGACCTCCA CGTGAAGAGC AAGGTAGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIF2B ( NM_032559.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115948.4 Homo sapiens kinesin family member 2B (KIF2B), mRNA.

Price & Availability↑

CloneID	OHu30761
Clone ID Related Accession (Same CDS sequence)	NM_032559.5 , NM_032559.4
Accession Version	NM_032559.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550246400000
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF2B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB457485.1, AC019315.9 and AF333335.2. On Apr 13, 2007 this sequence version replaced NM_032559.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGCCAGCC AGTTCTGCCT CCCTGAATCC CCATGTCTCT CGCCCCTGAA ACCCTTGAAG 
CCACATTTCG GAGACATCCA AGAGGGCATC TACGTGGCGA TCCAGCGCAG TGACAAGCGG 
ATCCACCTCG CTGTGGTCAC GGAGATCAAC AGAGAAAACT ATTGGGTCAC GGTAGAGTGG 
GTGGAGAAAG CAGTCAAAAA AGGCAAGAAG ATTGACCTGG AGACCATACT CCTGCTGAAT 
CCAGCTCTGG ACTCTGCTGA ACACCCCATG CCGCCCCCGC CCTTATCCCC CTTGGCTCTG 
GCGCCCTCTT CGGCCATCAG GGACCAGCGT ACCGCCACGA AATGGGTTGC GATGATCCCC 
CAGAAAAACC AAACAGCCTC AGGGGACAGC CTGGATGTGA GGGTCCCCAG CAAACCTTGT 
CTGATGAAGC AGAAAAAGTC TCCCTGCCTC TGGGAAATCC AGAAACTGCA GGAGCAGCGG 
GAAAAGCGCA GGCGGCTGCA GCAGGAGATC CGAGCTAGAC GCGCCCTCGA TGTCAATACC 
AGAAACCCCA ACTACGAAAT CATGCACATG ATCGAAGAGT ATCGCAGGCA CCTGGACAGC 
AGCAAGATCT CAGTCCTGGA GCCCCCGCAA GAACATCGCA TCTGCGTCTG CGTGAGGAAG 
CGGCCTCTCA ACCAGCGAGA GACAACCTTA AAGGACCTGG ATATCATCAC CGTCCCCTCG 
GACAATGTGG TTATGGTGCA TGAGTCCAAG CAAAAGGTGG ACCTCACTCG CTACCTGCAG 
AACCAGACCT TCTGCTTCGA CCATGCCTTC GATGACAAAG CCTCCAACGA GTTGGTGTAC 
CAGTTCACCG CCCAGCCACT GGTGGAGTCC ATCTTCCGCA AGGGCATGGC CACCTGCTTT 
GCCTATGGGC AGACGGGAAG TGGGAAGACG TACACCATGG GTGGAGACTT TTCAGGAACG 
GCCCAAGATT GTTCTAAGGG CATTTATGCT CTGGTGGCAC AGGATGTCTT TCTCCTGCTC 
AGAAACTCCA CATATGAGAA GCTGGACCTC AAAGTCTATG GGACATTTTT TGAGATTTAT 
GGGGGCAAGG TGTATGATTT GTTGAACTGG AAGAAGAAGC TGCAAGTCCT TGAGGATGGC 
AATCAGCAAA TCCAAGTGGT CGGGCTGCAG GAGAAAGAGG TGTGTTGTGT GGAGGAAGTG 
CTGAACCTGG TGGAAATAGG GAATAGCTGT CGGACTTCCA GGCAAACACC TGTCAACGCT 
CACTCATCCA GGAGCCATGC AGTGTTCCAG ATCATCCTGA AGTCAGGACG GATAATGCAT 
GGCAAGTTTT CCCTCGTTGA TTTAGCTGGG AATGAAAGAG GAGCAGATAC AACCAAGGCC 
AGCCGGAAAA GGCAGCTGGA AGGGGCAGAG ATTAACAAGA GTCTTCTAGC CCTCAAAGAA 
TGTATTCTGG CTTTGGGTCA GAACAAGCCT CACACCCCAT TCAGAGCCAG CAAACTCACA 
CTGGTGCTCC GGGACTCCTT TATAGGCCAG AACTCCTCCA CTTGCATGAT TGCTACCATC 
TCTCCGGGGA TGACCTCTTG TGAAAACACT CTCAACACTT TAAGATATGC AAACAGAGTA 
AAAAAATTAA ATGTAGATGT AAGGCCCTAC CATCGTGGCC ACTATCCGAT TGGACATGAG 
GCACCAAGGA TGTTAAAAAG TCACATCGGA AATTCAGAAA TGTCCCTTCA GAGGGATGAA 
TTTATTAAAA TACCTTATGT ACAGAGTGAG GAGCAGAAAG AGATTGAAGA GGTTGAAACA 
TTACCCACTC TGTTAGGGAA GGATACCACA ATTTCAGGGA AGGGATCTAG CCAATGGCTG 
GAAAACATCC AGGAGAGAGC TGGTGGAGTA CACCATGATA TTGATTTTTG CATTGCCCGG 
TCTTTGTCCA TTTTGGAGCA GAAAATTGAT GCTCTGACCG AGATCCAAAA GAAACTGAAA 
TTATTACTAG CTGACCTCCA CGTGAAGAGC AAGGTAGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115948.4
CDS	157..2178
Translation	MASQFCLPESPCLSPLKPLKPHFGDIQEGIYVAIQRSDKRIHLAVVTEINRENYWVTVEWVEKAVKKGKKIDLETILLLNPALDSAEHPMPPPPLSPLALAPSSAIRDQRTATKWVAMIPQKNQTASGDSLDVRVPSKPCLMKQKKSPCLWEIQKLQEQREKRRRLQQEIRARRALDVNTRNPNYEIMHMIEEYRRHLDSSKISVLEPPQEHRICVCVRKRPLNQRETTLKDLDIITVPSDNVVMVHESKQKVDLTRYLQNQTFCFDHAFDDKASNELVYQFTAQPLVESIFRKGMATCFAYGQTGSGKTYTMGGDFSGTAQDCSKGIYALVAQDVFLLLRNSTYEKLDLKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGNQQIQVVGLQEKEVCCVEEVLNLVEIGNSCRTSRQTPVNAHSSRSHAVFQIILKSGRIMHGKFSLVDLAGNERGADTTKASRKRQLEGAEINKSLLALKECILALGQNKPHTPFRASKLTLVLRDSFIGQNSSTCMIATISPGMTSCENTLNTLRYANRVKKLNVDVRPYHRGHYPIGHEAPRMLKSHIGNSEMSLQRDEFIKIPYVQSEEQKEIEEVETLPTLLGKDTTISGKGSSQWLENIQERAGGVHHDIDFCIARSLSILEQKIDALTEIQKKLKLLLADLHVKSKVE

Target ORF information:

RefSeq Version	NM_032559.4
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 2B (KIF2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032559.4

ORF Insert Sequence:

ATGGCCAGCC AGTTCTGCCT CCCTGAATCC CCATGTCTCT CGCCCCTGAA ACCCTTGAAG 
CCACATTTCG GAGACATCCA AGAGGGCATC TACGTGGCGA TCCAGCGCAG TGACAAGCGG 
ATCCACCTCG CTGTGGTCAC GGAGATCAAC AGAGAAAACT ATTGGGTCAC GGTAGAGTGG 
GTGGAGAAAG CAGTCAAAAA AGGCAAGAAG ATTGACCTGG AGACCATACT CCTGCTGAAT 
CCAGCTCTGG ACTCTGCTGA ACACCCCATG CCGCCCCCGC CCTTATCCCC CTTGGCTCTG 
GCGCCCTCTT CGGCCATCAG GGACCAGCGT ACCGCCACGA AATGGGTTGC GATGATCCCC 
CAGAAAAACC AAACAGCCTC AGGGGACAGC CTGGATGTGA GGGTCCCCAG CAAACCTTGT 
CTGATGAAGC AGAAAAAGTC TCCCTGCCTC TGGGAAATCC AGAAACTGCA GGAGCAGCGG 
GAAAAGCGCA GGCGGCTGCA GCAGGAGATC CGAGCTAGAC GCGCCCTCGA TGTCAATACC 
AGAAACCCCA ACTACGAAAT CATGCACATG ATCGAAGAGT ATCGCAGGCA CCTGGACAGC 
AGCAAGATCT CAGTCCTGGA GCCCCCGCAA GAACATCGCA TCTGCGTCTG CGTGAGGAAG 
CGGCCTCTCA ACCAGCGAGA GACAACCTTA AAGGACCTGG ATATCATCAC CGTCCCCTCG 
GACAATGTGG TTATGGTGCA TGAGTCCAAG CAAAAGGTGG ACCTCACTCG CTACCTGCAG 
AACCAGACCT TCTGCTTCGA CCATGCCTTC GATGACAAAG CCTCCAACGA GTTGGTGTAC 
CAGTTCACCG CCCAGCCACT GGTGGAGTCC ATCTTCCGCA AGGGCATGGC CACCTGCTTT 
GCCTATGGGC AGACGGGAAG TGGGAAGACG TACACCATGG GTGGAGACTT TTCAGGAACG 
GCCCAAGATT GTTCTAAGGG CATTTATGCT CTGGTGGCAC AGGATGTCTT TCTCCTGCTC 
AGAAACTCCA CATATGAGAA GCTGGACCTC AAAGTCTATG GGACATTTTT TGAGATTTAT 
GGGGGCAAGG TGTATGATTT GTTGAACTGG AAGAAGAAGC TGCAAGTCCT TGAGGATGGC 
AATCAGCAAA TCCAAGTGGT CGGGCTGCAG GAGAAAGAGG TGTGTTGTGT GGAGGAAGTG 
CTGAACCTGG TGGAAATAGG GAATAGCTGT CGGACTTCCA GGCAAACACC TGTCAACGCT 
CACTCATCCA GGAGCCATGC AGTGTTCCAG ATCATCCTGA AGTCAGGACG GATAATGCAT 
GGCAAGTTTT CCCTCGTTGA TTTAGCTGGG AATGAAAGAG GAGCAGATAC AACCAAGGCC 
AGCCGGAAAA GGCAGCTGGA AGGGGCAGAG ATTAACAAGA GTCTTCTAGC CCTCAAAGAA 
TGTATTCTGG CTTTGGGTCA GAACAAGCCT CACACCCCAT TCAGAGCCAG CAAACTCACA 
CTGGTGCTCC GGGACTCCTT TATAGGCCAG AACTCCTCCA CTTGCATGAT TGCTACCATC 
TCTCCGGGGA TGACCTCTTG TGAAAACACT CTCAACACTT TAAGATATGC AAACAGAGTA 
AAAAAATTAA ATGTAGATGT AAGGCCCTAC CATCGTGGCC ACTATCCGAT TGGACATGAG 
GCACCAAGGA TGTTAAAAAG TCACATCGGA AATTCAGAAA TGTCCCTTCA GAGGGATGAA 
TTTATTAAAA TACCTTATGT ACAGAGTGAG GAGCAGAAAG AGATTGAAGA GGTTGAAACA 
TTACCCACTC TGTTAGGGAA GGATACCACA ATTTCAGGGA AGGGATCTAG CCAATGGCTG 
GAAAACATCC AGGAGAGAGC TGGTGGAGTA CACCATGATA TTGATTTTTG CATTGCCCGG 
TCTTTGTCCA TTTTGGAGCA GAAAATTGAT GCTCTGACCG AGATCCAAAA GAAACTGAAA 
TTATTACTAG CTGACCTCCA CGTGAAGAGC AAGGTAGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phosphorylation of SKAP by GSK3β ensures chromosome segregation by a temporal inhibition of Kif2b activity.
Scientific reports638791(2016 12)
Qin B,Cao D,Wu H,Mo F,Shao H,Chu J,Powell M,Aikhionbare F,Wang D,Fu C,He P,Pan W,Wang W,Liu X,Yao X

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
The Journal of cell biology210(5)737-51(2015 Aug)
Watanabe T,Kakeno M,Matsui T,Sugiyama I,Arimura N,Matsuzawa K,Shirahige A,Ishidate F,Nishioka T,Taya S,Hoshino M,Kaibuchi K

Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK.
Current biology : CB23(16)1514-26(2013 Aug)
Shrestha RL,Draviam VM

The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.
Molecular biology of the cell23(24)4786-95(2012 Dec)
Welburn JP,Cheeseman IM

Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
Molecular biology of the cell23(12)2264-74(2012 Jun)
Hood EA,Kettenbach AN,Gerber SA,Compton DA

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KIF2B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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