SHARPIN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SHARPIN
Entrez Gene ID	81858
Full Name	SHANK associated RH domain interactor
Synonyms	SIPL1
General protein information	Preferred Names SHANK associated RH domain interactor Names sharpin hSIPL1 shank-associated RH domain-interacting protein shank-interacting protein-like 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q24.3
Disorder MIM:	611885

mRNA and Protein(s)

mRNA	Protein	Name
NM_030974.3	NP_112236.3	sharpin
XM_017013887.2	XP_016869376.1	sharpin isoform X1
XM_017013887.1	XP_016869376.1	sharpin isoform X1
XM_017013888.1	XP_016869377.1	sharpin isoform X2
XM_017013888.2	XP_016869377.1	sharpin isoform X2
NM_030974.4	NP_112236.3	sharpin

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SHARPIN	XP_001156216.2
Mus musculus (house mouse)	Sharpin	NP_079616.2
Homo sapiens (human)	SHARPIN	NP_112236.3
Rattus norvegicus (Norway rat)	Sharpin	NP_112415.1
Danio rerio (zebrafish)	LOC793673	XP_001333481.5
Macaca mulatta (Rhesus monkey)	LOC713534	XP_001102921.2
Bos taurus (cattle)	SHARPIN	NP_001103236.1
Canis lupus familiaris (dog)	SHARPIN	XP_532352.3

Gene Ontology
Bibliography

Related articles in PubMed

SHARPIN at the nexus of integrin, immune, and inflammatory signaling in human platelets.
Kasirer-Friede A, Tjahjono W, Eto K, Shattil SJ
Proceedings of the National Academy of Sciences of the United States of America116(11)4983-4988(2019 03)

Down-regulated SHARPIN may accelerate the development of atopic dermatitis through activating interleukin-33/ST2 signalling.
Tang L, Wang J, Zhu J, Liang Y
Experimental dermatology27(12)1328-1335(2018 12)

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.
Van Quickelberghe E, De Sutter D, van Loo G, Eyckerman S, Gevaert K
Scientific data5180289(2018 12)

A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer.
Ojo D, Wu Y, Bane A, Tang D
Biochimica et biophysica acta. Molecular basis of disease1864(3)735-745(2018 Mar)

SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.
Tamiya H, Kim H, Klymenko O, Kim H, Feng Y, Zhang T, Han JY, Murao A, Snipas SJ, Jilaveanu L, Brown K, Kluger H, Zhang H, Iwai K, Ronai ZA
The Journal of clinical investigation128(1)517-530(2018 01)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SHARPIN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SHARPIN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu98235	XM_017013887.2 Latest version!	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu98236	XM_017013888.2 Latest version!	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu04571	NM_030974.4 Latest version!	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu98235	XM_017013887.1	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu98236	XM_017013888.1	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu04571	NM_030974.3	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SHARPIN ( NM_030974.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_112236.3 Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04571
Clone ID Related Accession (Same CDS sequence)	NM_030974.3 , NM_030974.4
Accession Version	NM_030974.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514649600000
Organism	Homo sapiens(human)
Product	sharpin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC025244.1, BI911222.1, AK075518.1, AL136816.1, BE877614.1 and BC017230.2. On Dec 7, 2006 this sequence version replaced NM_030974.2. Transcript Variant: This variant (1) includes all coding exons, is not a candidate for nonsense-mediated decay, and encodes the protein product. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK075518.1, ERR279837.3182.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2161674 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCACAGGA CCTAGCCCTC AGCACCCCCA GAAGATGGAC 
GGGGAACTTG GACGCTTGTT TCCCCCATCA TTGGGGCTAC CCCCAGGCCC CCAGCCAGCT 
GCCTCCAGCC TGCCCAGTCC ACTCCAGCCC AGCTGGTCCT GTCCTTCCTG CACCTTCATC 
AATGCCCCAG ACCGCCCTGG CTGTGAGATG TGTAGCACCC AGAGGCCCTG CACTTGGGAC 
CCCCTTGCTG CAGCTTCCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112236.3
CDS	485..1648
Translation	MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPATGPSPQHPQKMDGELGRLFPPSLGLPPGPQPAASSLPSPLQPSWSCPSCTFINAPDRPGCEMCSTQRPCTWDPLAAAST

Target ORF information:

RefSeq Version	NM_030974.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030974.3

ORF Insert Sequence:

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCACAGGA CCTAGCCCTC AGCACCCCCA GAAGATGGAC 
GGGGAACTTG GACGCTTGTT TCCCCCATCA TTGGGGCTAC CCCCAGGCCC CCAGCCAGCT 
GCCTCCAGCC TGCCCAGTCC ACTCCAGCCC AGCTGGTCCT GTCCTTCCTG CACCTTCATC 
AATGCCCCAG ACCGCCCTGG CTGTGAGATG TGTAGCACCC AGAGGCCCTG CACTTGGGAC 
CCCCTTGCTG CAGCTTCCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHARPIN ( XM_017013887.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869376.1 Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu98235
Clone ID Related Accession (Same CDS sequence)	XM_017013887.2 , XM_017013887.1
Accession Version	XM_017013887.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	sharpin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013887.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGGACCTAGC CCTCAGCACC CCCAGAAGAT GGACGGGGAA 
CTTGGACGCT TGTTTCCCCC ATCATTGGGG CTACCCCCAG GCCCCCAGCC AGCTGCCTCC 
AGCCTGCCCA GTCCACTCCA GCCCAGCTGG TCCTGTCCTT CCTGCACCTT CATCAATGCC 
CCAGACCGCC CTGGCTGTGA GATGTGTAGC ACCCAGAGGC CCTGCACTTG GGACCCCCTT 
GCTGCAGCTT CCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869376.1
CDS	496..1653
Translation	MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPGPSPQHPQKMDGELGRLFPPSLGLPPGPQPAASSLPSPLQPSWSCPSCTFINAPDRPGCEMCSTQRPCTWDPLAAAST

Target ORF information:

RefSeq Version	XM_017013887.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013887.2

ORF Insert Sequence:

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGGACCTAGC CCTCAGCACC CCCAGAAGAT GGACGGGGAA 
CTTGGACGCT TGTTTCCCCC ATCATTGGGG CTACCCCCAG GCCCCCAGCC AGCTGCCTCC 
AGCCTGCCCA GTCCACTCCA GCCCAGCTGG TCCTGTCCTT CCTGCACCTT CATCAATGCC 
CCAGACCGCC CTGGCTGTGA GATGTGTAGC ACCCAGAGGC CCTGCACTTG GGACCCCCTT 
GCTGCAGCTT CCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHARPIN ( XM_017013887.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869376.1 Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu98235
Clone ID Related Accession (Same CDS sequence)	XM_017013887.2 , XM_017013887.1
Accession Version	XM_017013887.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	sharpin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGGACCTAGC CCTCAGCACC CCCAGAAGAT GGACGGGGAA 
CTTGGACGCT TGTTTCCCCC ATCATTGGGG CTACCCCCAG GCCCCCAGCC AGCTGCCTCC 
AGCCTGCCCA GTCCACTCCA GCCCAGCTGG TCCTGTCCTT CCTGCACCTT CATCAATGCC 
CCAGACCGCC CTGGCTGTGA GATGTGTAGC ACCCAGAGGC CCTGCACTTG GGACCCCCTT 
GCTGCAGCTT CCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869376.1
CDS	513..1670
Translation	MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPGPSPQHPQKMDGELGRLFPPSLGLPPGPQPAASSLPSPLQPSWSCPSCTFINAPDRPGCEMCSTQRPCTWDPLAAAST

Target ORF information:

RefSeq Version	XM_017013887.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013887.1

ORF Insert Sequence:

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGGACCTAGC CCTCAGCACC CCCAGAAGAT GGACGGGGAA 
CTTGGACGCT TGTTTCCCCC ATCATTGGGG CTACCCCCAG GCCCCCAGCC AGCTGCCTCC 
AGCCTGCCCA GTCCACTCCA GCCCAGCTGG TCCTGTCCTT CCTGCACCTT CATCAATGCC 
CCAGACCGCC CTGGCTGTGA GATGTGTAGC ACCCAGAGGC CCTGCACTTG GGACCCCCTT 
GCTGCAGCTT CCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHARPIN ( XM_017013888.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869377.1 Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu98236
Clone ID Related Accession (Same CDS sequence)	XM_017013888.1 , XM_017013888.2
Accession Version	XM_017013888.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	sharpin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCCAGCTG GTCCTGTCCT TCCTGCACCT TCATCAATGC 
CCCAGACCGC CCTGGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869377.1
CDS	513..1493
Translation	MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPAQLVLSFLHLHQCPRPPWL

Target ORF information:

RefSeq Version	XM_017013888.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013888.1

ORF Insert Sequence:

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCCAGCTG GTCCTGTCCT TCCTGCACCT TCATCAATGC 
CCCAGACCGC CCTGGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHARPIN ( XM_017013888.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869377.1 Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu98236
Clone ID Related Accession (Same CDS sequence)	XM_017013888.1 , XM_017013888.2
Accession Version	XM_017013888.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	sharpin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013888.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCCAGCTG GTCCTGTCCT TCCTGCACCT TCATCAATGC 
CCCAGACCGC CCTGGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869377.1
CDS	496..1476
Translation	MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPAQLVLSFLHLHQCPRPPWL

Target ORF information:

RefSeq Version	XM_017013888.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013888.2

ORF Insert Sequence:

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCCAGCTG GTCCTGTCCT TCCTGCACCT TCATCAATGC 
CCCAGACCGC CCTGGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHARPIN ( NM_030974.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_112236.3 Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04571
Clone ID Related Accession (Same CDS sequence)	NM_030974.3 , NM_030974.4
Accession Version	NM_030974.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572105600000
Organism	Homo sapiens(human)
Product	sharpin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL136816.1 and BE877614.1. On Nov 22, 2018 this sequence version replaced NM_030974.3. Transcript Variant: This variant (1) includes all coding exons, is not a candidate for nonsense-mediated decay, and encodes the protein product. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL136816.1, FJ655995.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2161674 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000398712.7/ ENSP00000381698.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCACAGGA CCTAGCCCTC AGCACCCCCA GAAGATGGAC 
GGGGAACTTG GACGCTTGTT TCCCCCATCA TTGGGGCTAC CCCCAGGCCC CCAGCCAGCT 
GCCTCCAGCC TGCCCAGTCC ACTCCAGCCC AGCTGGTCCT GTCCTTCCTG CACCTTCATC 
AATGCCCCAG ACCGCCCTGG CTGTGAGATG TGTAGCACCC AGAGGCCCTG CACTTGGGAC 
CCCCTTGCTG CAGCTTCCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112236.3
CDS	21..1184
Translation	MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPATGPSPQHPQKMDGELGRLFPPSLGLPPGPQPAASSLPSPLQPSWSCPSCTFINAPDRPGCEMCSTQRPCTWDPLAAAST

Target ORF information:

RefSeq Version	NM_030974.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SHANK associated RH domain interactor (SHARPIN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030974.4

ORF Insert Sequence:

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCGGCCTCGG ACTTGGGCTC CGCCGCAGTG 
CTCTTGGCTG TGCACGCCGC GGTGAGGCCG CTGGGCGCCG GGCCAGACGC CGAGGCACAG 
CTGCGGAGGC TGCAGCTGAG CGCGGACCCT GAGCGGCCTG GGCGCTTCCG GCTGGAGCTG 
CTGGGCGCGG GACCTGGGGC GGTTAATTTG GAGTGGCCCC TGGAGTCAGT TTCCTACACC 
ATCCGAGGCC CCACCCAGCA CGAGCTACAG CCTCCACCAG GAGGGCCTGG AACCCTCAGC 
CTGCACTTCC TCAACCCTCA GGAAGCTCAG CGGTGGGCAG TCCTAGTCCG AGGTGCCACC 
GTGGAAGGAC AGAATGGCAG CAAGAGCAAC TCACCACCAG CCTTGGGCCC AGAAGCATGC 
CCTGTCTCCC TGCCCAGTCC CCCGGAAGCC TCCACACTCA AGGGCCCTCC ACCTGAGGCA 
GATCTTCCTA GGAGCCCTGG AAACTTGACG GAGAGAGAAG AGCTGGCAGG GAGCCTGGCC 
CGGGCTATTG CAGGTGGAGA CGAGAAGGGG GCAGCCCAAG TGGCAGCCGT CCTGGCCCAG 
CATCGTGTGG CCCTGAGTGT TCAGCTTCAG GAGGCCTGCT TCCCACCTGG CCCCATCAGG 
CTGCAGGTCA CACTTGAAGA CGCTGCCTCT GCCGCATCCG CCGCGTCCTC TGCACACGTT 
GCCCTGCAGG TCCACCCCCA CTGCACTGTT GCAGCTCTCC AGGAGCAGGT GTTCTCAGAG 
CTCGGTTTCC CGCCAGCCGT GCAACGCTGG GTCATCGGAC GGTGCCTGTG TGTGCCTGAG 
CGCAGCCTTG CCTCTTACGG GGTTCGGCAG GATGGGGACC CTGCTTTCCT CTACTTGCTG 
TCAGCTCCTC GAGAAGCCCC AGCCACAGGA CCTAGCCCTC AGCACCCCCA GAAGATGGAC 
GGGGAACTTG GACGCTTGTT TCCCCCATCA TTGGGGCTAC CCCCAGGCCC CCAGCCAGCT 
GCCTCCAGCC TGCCCAGTCC ACTCCAGCCC AGCTGGTCCT GTCCTTCCTG CACCTTCATC 
AATGCCCCAG ACCGCCCTGG CTGTGAGATG TGTAGCACCC AGAGGCCCTG CACTTGGGAC 
CCCCTTGCTG CAGCTTCCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SHARPIN at the nexus of integrin, immune, and inflammatory signaling in human platelets.
Proceedings of the National Academy of Sciences of the United States of America116(11)4983-4988(2019 03)
Kasirer-Friede A,Tjahjono W,Eto K,Shattil SJ

Down-regulated SHARPIN may accelerate the development of atopic dermatitis through activating interleukin-33/ST2 signalling.
Experimental dermatology27(12)1328-1335(2018 12)
Tang L,Wang J,Zhu J,Liang Y

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.
Scientific data5180289(2018 12)
Van Quickelberghe E,De Sutter D,van Loo G,Eyckerman S,Gevaert K

A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer.
Biochimica et biophysica acta. Molecular basis of disease1864(3)735-745(2018 Mar)
Ojo D,Wu Y,Bane A,Tang D

SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.
The Journal of clinical investigation128(1)517-530(2018 01)
Tamiya H,Kim H,Klymenko O,Kim H,Feng Y,Zhang T,Han JY,Murao A,Snipas SJ,Jilaveanu L,Brown K,Kluger H,Zhang H,Iwai K,Ronai ZA

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SHARPIN cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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