GLRA3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GLRA3
Entrez Gene ID	8001
Full Name	glycine receptor alpha 3
General protein information	Preferred Names glycine receptor alpha 3 Names glycine receptor subunit alpha-3 glycine receptor, alpha-3 polypeptide ligand gated ion channel
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q34.1
Summary	This gene encodes a member of the ligand-gated ion channel protein family. The encoded protein is a member of the glycine receptor subfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013].
Disorder MIM:	600421

mRNA and Protein(s)

mRNA	Protein	Name
NM_001042543.2	NP_001036008.1	glycine receptor subunit alpha-3 isoform b precursor
NM_001042543.3	NP_001036008.1	glycine receptor subunit alpha-3 isoform b precursor
XM_011532267.2	XP_011530569.1	glycine receptor subunit alpha-3 isoform X2
NM_006529.4	NP_006520.2	glycine receptor subunit alpha-3 isoform a precursor
XM_017008630.1	XP_016864119.1	glycine receptor subunit alpha-3 isoform X1
NM_006529.3	NP_006520.2	glycine receptor subunit alpha-3 isoform a precursor
XM_011532268.2	XP_011530570.1	glycine receptor subunit alpha-3 isoform X3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GLRA3	XP_517543.2
Danio rerio (zebrafish)	glra3	NP_694497.1
Caenorhabditis elegans (roundworm)	glc-2	NP_491470.1
Homo sapiens (human)	GLRA3	NP_006520.2
Mus musculus (house mouse)	Glra3	NP_536686.2
Xenopus tropicalis (tropical clawed frog)	glra3	XP_002933371.1
Macaca mulatta (Rhesus monkey)	GLRA3	XP_001088083.1
Canis lupus familiaris (dog)	GLRA3	XP_003433410.1
Bos taurus (cattle)	GLRA3	XP_003586404.1
Rattus norvegicus (Norway rat)	Glra3	NP_446176.3
Gallus gallus (chicken)	GLRA3	XP_420527.2

Gene Ontology
Bibliography

Related articles in PubMed

Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes.
Sandholm N, Haukka JK, Toppila I, Valo E, Harjutsalo V, Forsblom C, Groop PH
Scientific reports8(1)12408(2018 08)

Identification of Novel Functionally Important Aromatic Residue Interactions in the Extracellular Domain of the Glycine Receptor.
Tang B, Devenish SO, Lummis SCR
Biochemistry57(27)4029-4035(2018 07)

Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.
Patrizio A, Renner M, Pizzarelli R, Triller A, Specht CG
Scientific reports7(1)10899(2017 09)

Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators.
Huang X, Shaffer PL, Ayube S, Bregman H, Chen H, Lehto SG, Luther JA, Matson DJ, McDonough SI, Michelsen K, Plant MH, Schneider S, Simard JR, Teffera Y, Yi S, Zhang M, DiMauro EF, Gingras J
Nature structural & molecular biology24(2)108-113(2017 02)

Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.
Raltschev C, Hetsch F, Winkelmann A, Meier JC, Semtner M
The Journal of biological chemistry291(34)18030-40(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GLRA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GLRA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11792	NM_001042543.3 Latest version!	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu61582	XM_011532267.2 Latest version!	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu61583	XM_011532268.2 Latest version!	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu95409	XM_017008630.1 Latest version!	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu10716	NM_006529.4 Latest version!	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu11792	NM_001042543.2	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu10716	NM_006529.3	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GLRA3 ( NM_001042543.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036008.1 Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 2, mRNA.

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CloneID	OHu11792
Clone ID Related Accession (Same CDS sequence)	NM_001042543.2 , NM_001042543.3
Accession Version	NM_001042543.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530201600000
Organism	Homo sapiens(human)
Product	glycine receptor subunit alpha-3 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI600831.1, BC036086.1, AC107216.5 and U93917.1. On Nov 13, 2013 this sequence version replaced NM_001042543.1. Transcript Variant: This variant (2, also known as alpha3K) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U93917.1, SRR1803613.211947.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GGATGATGAG 
GTAAGGGAAA GCCGATTCAG CTTCACAGCC TATGGAATGG GACCATGTCT ACAAGCAAAG 
GATGGCATGA CTCCAAAGGG CCCCAACCAC CCTGTCCAGG TAATGCCAAA AAGTCCTGAT 
GAAATGAGGA AGGTCTTTAT CGACCGGGCC AAGAAGATTG ATACCATCTC CCGAGCCTGC 
TTCCCATTAG CTTTTTTGAT TTTTAATATT TTCTACTGGG TTATCTATAA AATTCTTAGG 
CATGAGGATA TTCATCAGCA GCAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036008.1
CDS	505..1854
Translation	MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD

Target ORF information:

RefSeq Version	NM_001042543.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042543.2

ORF Insert Sequence:

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GGATGATGAG 
GTAAGGGAAA GCCGATTCAG CTTCACAGCC TATGGAATGG GACCATGTCT ACAAGCAAAG 
GATGGCATGA CTCCAAAGGG CCCCAACCAC CCTGTCCAGG TAATGCCAAA AAGTCCTGAT 
GAAATGAGGA AGGTCTTTAT CGACCGGGCC AAGAAGATTG ATACCATCTC CCGAGCCTGC 
TTCCCATTAG CTTTTTTGAT TTTTAATATT TTCTACTGGG TTATCTATAA AATTCTTAGG 
CATGAGGATA TTCATCAGCA GCAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLRA3 ( NM_001042543.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036008.1 Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11792
Clone ID Related Accession (Same CDS sequence)	NM_001042543.2 , NM_001042543.3
Accession Version	NM_001042543.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572105600000
Organism	Homo sapiens(human)
Product	glycine receptor subunit alpha-3 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036086.1, AC107216.5 and U93917.1. On May 31, 2019 this sequence version replaced NM_001042543.2. Transcript Variant: This variant (2, also known as alpha3K) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U93917.1, SRR1803613.211947.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GGATGATGAG 
GTAAGGGAAA GCCGATTCAG CTTCACAGCC TATGGAATGG GACCATGTCT ACAAGCAAAG 
GATGGCATGA CTCCAAAGGG CCCCAACCAC CCTGTCCAGG TAATGCCAAA AAGTCCTGAT 
GAAATGAGGA AGGTCTTTAT CGACCGGGCC AAGAAGATTG ATACCATCTC CCGAGCCTGC 
TTCCCATTAG CTTTTTTGAT TTTTAATATT TTCTACTGGG TTATCTATAA AATTCTTAGG 
CATGAGGATA TTCATCAGCA GCAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036008.1
CDS	437..1786
Translation	MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD

Target ORF information:

RefSeq Version	NM_001042543.3
Organism	Homo sapiens(human)
Definition	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042543.3

ORF Insert Sequence:

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GGATGATGAG 
GTAAGGGAAA GCCGATTCAG CTTCACAGCC TATGGAATGG GACCATGTCT ACAAGCAAAG 
GATGGCATGA CTCCAAAGGG CCCCAACCAC CCTGTCCAGG TAATGCCAAA AAGTCCTGAT 
GAAATGAGGA AGGTCTTTAT CGACCGGGCC AAGAAGATTG ATACCATCTC CCGAGCCTGC 
TTCCCATTAG CTTTTTTGAT TTTTAATATT TTCTACTGGG TTATCTATAA AATTCTTAGG 
CATGAGGATA TTCATCAGCA GCAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLRA3 ( XM_011532267.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530569.1 Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu61582
Clone ID Related Accession (Same CDS sequence)	XM_011532267.2
Accession Version	XM_011532267.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	glycine receptor subunit alpha-3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532267.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGCT AACGTTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530569.1
CDS	758..1699
Translation	MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKANVS

Target ORF information:

RefSeq Version	XM_011532267.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532267.2

ORF Insert Sequence:

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGCT AACGTTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLRA3 ( XM_011532268.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530570.1 Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X5, mRNA.

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CloneID	OHu61583
Clone ID Related Accession (Same CDS sequence)	XM_011532268.2
Accession Version	XM_011532268.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	glycine receptor subunit alpha-3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532268.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGATC TCATTTTTGA ATGGCAAGAT GAGGCACCCG TACAAGTGGC AGAAGGACTC 
ACTTTGCCCC AGTTTCTGTT GAAAGAAGAA AAAGATTTAC GATACTGCAC TAAACATTAC 
AATACAGGAA AGTTTACGTG TATAGAAGTG CGATTCCATC TGGAGCGACA AATGGGATAC 
TATCTGATCC AGATGTACAT TCCCAGTCTC CTGATTGTTA TTCTATCCTG GGTTTCATTC 
TGGATCAACA TGGATGCAGC ACCGGCCAGG GTAGCTCTGG GGATAACCAC TGTGCTAACG 
ATGACTACAC AGAGTTCAGG ATCACGAGCT TCCTTGCCAA AAGTTTCATA TGTCAAAGCT 
ATTGATATTT GGATGGCAGT ATGCCTCCTT TTTGTGTTTT CAGCACTTCT GGAGTATGCA 
GCTGTAAATT TTGTATCAAG ACAACACAAA GAACTTCTGA GATTTCGACG AAAGAGAAAG 
AATAAGACAG AAGCTTTTGC ACTGGAGAAG TTTTACCGTT TCTCAGATAT GGATGATGAG 
GTAAGGGAAA GCCGATTCAG CTTCACAGCC TATGGAATGG GACCATGTCT ACAAGCAAAG 
GATGGCATGA CTCCAAAGGG CCCCAACCAC CCTGTCCAGG TAATGCCAAA AAGTCCTGAT 
GAAATGAGGA AGGTCTTTAT CGACCGGGCC AAGAAGATTG ATACCATCTC CCGAGCCTGC 
TTCCCATTAG CTTTTTTGAT TTTTAATATT TTCTACTGGG TTATCTATAA AATTCTTAGG 
CATGAGGATA TTCATCAGCA GCAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530570.1
CDS	336..1145
Translation	MNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD

Target ORF information:

RefSeq Version	XM_011532268.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532268.2

ORF Insert Sequence:

ATGAATGATC TCATTTTTGA ATGGCAAGAT GAGGCACCCG TACAAGTGGC AGAAGGACTC 
ACTTTGCCCC AGTTTCTGTT GAAAGAAGAA AAAGATTTAC GATACTGCAC TAAACATTAC 
AATACAGGAA AGTTTACGTG TATAGAAGTG CGATTCCATC TGGAGCGACA AATGGGATAC 
TATCTGATCC AGATGTACAT TCCCAGTCTC CTGATTGTTA TTCTATCCTG GGTTTCATTC 
TGGATCAACA TGGATGCAGC ACCGGCCAGG GTAGCTCTGG GGATAACCAC TGTGCTAACG 
ATGACTACAC AGAGTTCAGG ATCACGAGCT TCCTTGCCAA AAGTTTCATA TGTCAAAGCT 
ATTGATATTT GGATGGCAGT ATGCCTCCTT TTTGTGTTTT CAGCACTTCT GGAGTATGCA 
GCTGTAAATT TTGTATCAAG ACAACACAAA GAACTTCTGA GATTTCGACG AAAGAGAAAG 
AATAAGACAG AAGCTTTTGC ACTGGAGAAG TTTTACCGTT TCTCAGATAT GGATGATGAG 
GTAAGGGAAA GCCGATTCAG CTTCACAGCC TATGGAATGG GACCATGTCT ACAAGCAAAG 
GATGGCATGA CTCCAAAGGG CCCCAACCAC CCTGTCCAGG TAATGCCAAA AAGTCCTGAT 
GAAATGAGGA AGGTCTTTAT CGACCGGGCC AAGAAGATTG ATACCATCTC CCGAGCCTGC 
TTCCCATTAG CTTTTTTGAT TTTTAATATT TTCTACTGGG TTATCTATAA AATTCTTAGG 
CATGAGGATA TTCATCAGCA GCAAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLRA3 ( XM_017008630.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864119.1 Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X1, mRNA.

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CloneID	OHu95409
Clone ID Related Accession (Same CDS sequence)	XM_017008630.1
Accession Version	XM_017008630.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1275bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	glycine receptor subunit alpha-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GACAGAAGCT 
TTTGCACTGG AGAAGTTTTA CCGTTTCTCA GATATGGATG ATGAGGTAAG GGAAAGCCGA 
TTCAGCTTCA CAGCCTATGG AATGGGACCA TGTCTACAAG CAAAGGATGG CATGACTCCA 
AAGGGCCCCA ACCACCCTGT CCAGGTAATG CCAAAAAGTC CTGATGAAAT GAGGAAGGTC 
TTTATCGACC GGGCCAAGAA GATTGATACC ATCTCCCGAG CCTGCTTCCC ATTAGCTTTT 
TTGATTTTTA ATATTTTCTA CTGGGTTATC TATAAAATTC TTAGGCATGA GGATATTCAT 
CAGCAGCAAG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864119.1
CDS	649..1923
Translation	MSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD

Target ORF information:

RefSeq Version	XM_017008630.1
Organism	Homo sapiens(human)
Definition	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008630.1

ORF Insert Sequence:

ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GACAGAAGCT 
TTTGCACTGG AGAAGTTTTA CCGTTTCTCA GATATGGATG ATGAGGTAAG GGAAAGCCGA 
TTCAGCTTCA CAGCCTATGG AATGGGACCA TGTCTACAAG CAAAGGATGG CATGACTCCA 
AAGGGCCCCA ACCACCCTGT CCAGGTAATG CCAAAAAGTC CTGATGAAAT GAGGAAGGTC 
TTTATCGACC GGGCCAAGAA GATTGATACC ATCTCCCGAG CCTGCTTCCC ATTAGCTTTT 
TTGATTTTTA ATATTTTCTA CTGGGTTATC TATAAAATTC TTAGGCATGA GGATATTCAT 
CAGCAGCAAG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLRA3 ( NM_006529.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006520.2 Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 1, mRNA.

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CloneID	OHu10716
Clone ID Related Accession (Same CDS sequence)	NM_006529.4 , NM_006529.3
Accession Version	NM_006529.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572105600000
Organism	Homo sapiens(human)
Product	glycine receptor subunit alpha-3 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036086.1, AC107216.5 and AF018157.1. On Nov 22, 2018 this sequence version replaced NM_006529.3. Transcript Variant: This variant (1, also known as alpha3L) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036086.1, SRR1803614.124928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000274093.8/ ENSP00000274093.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GACAGAAGCT 
TTTGCACTGG AGAAGTTTTA CCGTTTCTCA GATATGGATG ATGAGGTAAG GGAAAGCCGA 
TTCAGCTTCA CAGCCTATGG AATGGGACCA TGTCTACAAG CAAAGGATGG CATGACTCCA 
AAGGGCCCCA ACCACCCTGT CCAGGTAATG CCAAAAAGTC CTGATGAAAT GAGGAAGGTC 
TTTATCGACC GGGCCAAGAA GATTGATACC ATCTCCCGAG CCTGCTTCCC ATTAGCTTTT 
TTGATTTTTA ATATTTTCTA CTGGGTTATC TATAAAATTC TTAGGCATGA GGATATTCAT 
CAGCAGCAAG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006520.2
CDS	437..1831
Translation	MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD

Target ORF information:

RefSeq Version	NM_006529.4
Organism	Homo sapiens(human)
Definition	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006529.4

ORF Insert Sequence:

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GACAGAAGCT 
TTTGCACTGG AGAAGTTTTA CCGTTTCTCA GATATGGATG ATGAGGTAAG GGAAAGCCGA 
TTCAGCTTCA CAGCCTATGG AATGGGACCA TGTCTACAAG CAAAGGATGG CATGACTCCA 
AAGGGCCCCA ACCACCCTGT CCAGGTAATG CCAAAAAGTC CTGATGAAAT GAGGAAGGTC 
TTTATCGACC GGGCCAAGAA GATTGATACC ATCTCCCGAG CCTGCTTCCC ATTAGCTTTT 
TTGATTTTTA ATATTTTCTA CTGGGTTATC TATAAAATTC TTAGGCATGA GGATATTCAT 
CAGCAGCAAG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLRA3 ( NM_006529.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006520.2 Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10716
Clone ID Related Accession (Same CDS sequence)	NM_006529.4 , NM_006529.3
Accession Version	NM_006529.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506873600000
Organism	Homo sapiens(human)
Product	glycine receptor subunit alpha-3 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI600831.1, BC036086.1, AC107216.5 and AF018157.1. On Nov 13, 2013 this sequence version replaced NM_006529.2. Transcript Variant: This variant (1, also known as alpha3L) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036086.1, SRR1803614.124928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GACAGAAGCT 
TTTGCACTGG AGAAGTTTTA CCGTTTCTCA GATATGGATG ATGAGGTAAG GGAAAGCCGA 
TTCAGCTTCA CAGCCTATGG AATGGGACCA TGTCTACAAG CAAAGGATGG CATGACTCCA 
AAGGGCCCCA ACCACCCTGT CCAGGTAATG CCAAAAAGTC CTGATGAAAT GAGGAAGGTC 
TTTATCGACC GGGCCAAGAA GATTGATACC ATCTCCCGAG CCTGCTTCCC ATTAGCTTTT 
TTGATTTTTA ATATTTTCTA CTGGGTTATC TATAAAATTC TTAGGCATGA GGATATTCAT 
CAGCAGCAAG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006520.2
CDS	505..1899
Translation	MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD

Target ORF information:

RefSeq Version	NM_006529.3
Organism	Homo sapiens(human)
Definition	Homo sapiens glycine receptor alpha 3 (GLRA3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006529.3

ORF Insert Sequence:

ATGGCCCACG TGAGACACTT TCGGACATTA GTTTCGGGAT TTTACTTCTG GGAAGCAGCA 
CTGTTACTCA GTTTGGTTGC CACAAAGGAA ACAGACAGTG CAAGATCTCG AAGTGCTCCA 
ATGTCACCTT CTGATTTTCT GGATAAATTA ATGGGCAGGA CATCAGGATA TGATGCAAGA 
ATCAGACCCA ATTTTAAAGG CCCTCCAGTT AATGTCACAT GCAACATATT CATCAACAGC 
TTTGGCTCTA TCGCAGAGAC GACCATGGAT TACAGAGTGA ATATCTTTCT TCGTCAGAAA 
TGGAATGATC CCCGCCTCGC GTACAGTGAA TATCCTGACG ACTCTTTAGA CCTCGACCCC 
TCCATGTTGG ACTCCATTTG GAAACCTGAT TTGTTCTTTG CCAATGAAAA GGGTGCCAAC 
TTTCATGAAG TCACTACAGA CAACAAATTG CTAAGAATTT TCAAAAATGG AAATGTTCTT 
TATTCAATAA GATTAACATT AACACTTTCC TGTCCAATGG ATCTCAAGAA TTTTCCCATG 
GATGTACAAA CATGTATAAT GCAACTGGAA AGCTTTGGGT ACACAATGAA TGATCTCATT 
TTTGAATGGC AAGATGAGGC ACCCGTACAA GTGGCAGAAG GACTCACTTT GCCCCAGTTT 
CTGTTGAAAG AAGAAAAAGA TTTACGATAC TGCACTAAAC ATTACAATAC AGGAAAGTTT 
ACGTGTATAG AAGTGCGATT CCATCTGGAG CGACAAATGG GATACTATCT GATCCAGATG 
TACATTCCCA GTCTCCTGAT TGTTATTCTA TCCTGGGTTT CATTCTGGAT CAACATGGAT 
GCAGCACCGG CCAGGGTAGC TCTGGGGATA ACCACTGTGC TAACGATGAC TACACAGAGT 
TCAGGATCAC GAGCTTCCTT GCCAAAAGTT TCATATGTCA AAGCTATTGA TATTTGGATG 
GCAGTATGCC TCCTTTTTGT GTTTTCAGCA CTTCTGGAGT ATGCAGCTGT AAATTTTGTA 
TCAAGACAAC ACAAAGAACT TCTGAGATTT CGACGAAAGA GAAAGAATAA GACAGAAGCT 
TTTGCACTGG AGAAGTTTTA CCGTTTCTCA GATATGGATG ATGAGGTAAG GGAAAGCCGA 
TTCAGCTTCA CAGCCTATGG AATGGGACCA TGTCTACAAG CAAAGGATGG CATGACTCCA 
AAGGGCCCCA ACCACCCTGT CCAGGTAATG CCAAAAAGTC CTGATGAAAT GAGGAAGGTC 
TTTATCGACC GGGCCAAGAA GATTGATACC ATCTCCCGAG CCTGCTTCCC ATTAGCTTTT 
TTGATTTTTA ATATTTTCTA CTGGGTTATC TATAAAATTC TTAGGCATGA GGATATTCAT 
CAGCAGCAAG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes.
Scientific reports8(1)12408(2018 08)
Sandholm N,Haukka JK,Toppila I,Valo E,Harjutsalo V,Forsblom C,Groop PH

Identification of Novel Functionally Important Aromatic Residue Interactions in the Extracellular Domain of the Glycine Receptor.
Biochemistry57(27)4029-4035(2018 07)
Tang B,Devenish SO,Lummis SCR

Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.
Scientific reports7(1)10899(2017 09)
Patrizio A,Renner M,Pizzarelli R,Triller A,Specht CG

Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators.
Nature structural & molecular biology24(2)108-113(2017 02)
Huang X,Shaffer PL,Ayube S,Bregman H,Chen H,Lehto SG,Luther JA,Matson DJ,McDonough SI,Michelsen K,Plant MH,Schneider S,Simard JR,Teffera Y,Yi S,Zhang M,DiMauro EF,Gingras J

Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.
The Journal of biological chemistry291(34)18030-40(2016 08)
Raltschev C,Hetsch F,Winkelmann A,Meier JC,Semtner M

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GLRA3 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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