TRIR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRIR
Entrez Gene ID	79002
Full Name	telomerase RNA component interacting RNase
Synonyms	C19orf43,TERCIR,fSAP18
General protein information	Preferred Names telomerase RNA component interacting RNase Names telomerase RNA component interacting RNase My029 protein exoribonuclease TRIR uncharacterized protein C19orf43
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001329739.2	NP_001316668.1	telomerase RNA component interacting RNase isoform 3
NM_024038.4	NP_076943.1	telomerase RNA component interacting RNase isoform 1
NM_024038.2	NP_076943.1	uncharacterized protein C19orf43
NM_001329738.1	NP_001316667.1	telomerase RNA component interacting RNase isoform 2
NM_001329738.2	NP_001316667.1	telomerase RNA component interacting RNase isoform 2
NM_001329739.1	NP_001316668.1	telomerase RNA component interacting RNase isoform 3
NM_024038.3	NP_076943.1	telomerase RNA component interacting RNase isoform 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC560758	XP_684751.1
Homo sapiens (human)	C19orf43	NP_076943.1
Pan troglodytes (chimpanzee)	C19H19orf43	XP_512412.1
Canis lupus familiaris (dog)	C20H19orf43	XP_533905.1
Bos taurus (cattle)	C7H19orf43	NP_001076840.1
Macaca mulatta (Rhesus monkey)	C19H19orf43	XP_001108705.1
Mus musculus (house mouse)	2310036O22Rik	NP_081036.2
Rattus norvegicus (Norway rat)	RGD1564093	NP_001099416.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of an RNase that preferentially cleaves A/G nucleotides.
Xie J, Chen Z, Zhang X, Chen H, Guan W
Scientific reports745207(2017 03)

Dynamic protein-protein interaction wiring of the human spliceosome.
Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, Lührmann R, Stelzl U
Molecular cell45(4)567-80(2012 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TRIR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRIR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu100588	NM_001329739.2 Latest version!	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu100591	NM_001329738.2 Latest version!	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu29817	NM_024038.4 Latest version!	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu29817	NM_024038.2	Homo sapiens chromosome 19 open reading frame 43 (C19orf43), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu100591	NM_001329738.1	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu100588	NM_001329739.1	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu29817	NM_024038.3	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRIR ( NM_001329739.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001316668.1 Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu100588
Clone ID Related Accession (Same CDS sequence)	NM_001329739.2 , NM_001329739.1
Accession Version	NM_001329739.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559145600000
Organism	Homo sapiens(human)
Product	telomerase RNA component interacting RNase isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018761.6. On May 31, 2019 this sequence version replaced NM_001329739.1. Transcript Variant: This variant (3) uses an alternate splice site, which results in a frameshift, compared to variant 1. The encoded protein (isoform 3) has a distinct, shorter C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.293743.1, BX376854.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155751, SAMEA2162946 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTGGGCAA ACGCAGAGGC GGGAACAAAC TAGCCCTCAA 
GACGGGAATA GTAGCCAAGA AGCAGAAGAC GGAGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001316668.1
CDS	28..426
Translation	MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQSAAAAGPGDPKRKGGGQTQRREQTSPQDGNSSQEAEDGG

Target ORF information:

RefSeq Version	NM_001329739.2
Organism	Homo sapiens(human)
Definition	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001329739.2

ORF Insert Sequence:

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTGGGCAA ACGCAGAGGC GGGAACAAAC TAGCCCTCAA 
GACGGGAATA GTAGCCAAGA AGCAGAAGAC GGAGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIR ( NM_001329739.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001316668.1 Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu100588
Clone ID Related Accession (Same CDS sequence)	NM_001329739.2 , NM_001329739.1
Accession Version	NM_001329739.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1545321600000
Organism	Homo sapiens(human)
Product	telomerase RNA component interacting RNase isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018761.6. Transcript Variant: This variant (3) uses an alternate splice site, which results in a frameshift, compared to variant 1. The encoded protein (isoform 3) has a distinct, shorter C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.293743.1, BX376854.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155751, SAMEA2162946 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTGGGCAA ACGCAGAGGC GGGAACAAAC TAGCCCTCAA 
GACGGGAATA GTAGCCAAGA AGCAGAAGAC GGAGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001316668.1
CDS	119..517
Translation	MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQSAAAAGPGDPKRKGGGQTQRREQTSPQDGNSSQEAEDGG

Target ORF information:

RefSeq Version	NM_001329739.1
Organism	Homo sapiens(human)
Definition	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001329739.1

ORF Insert Sequence:

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTGGGCAA ACGCAGAGGC GGGAACAAAC TAGCCCTCAA 
GACGGGAATA GTAGCCAAGA AGCAGAAGAC GGAGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIR ( NM_001329738.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001316667.1 Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu100591
Clone ID Related Accession (Same CDS sequence)	NM_001329738.1 , NM_001329738.2
Accession Version	NM_001329738.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1545321600000
Organism	Homo sapiens(human)
Product	telomerase RNA component interacting RNase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL559579.3, BQ668685.1, BU599327.1 and BC000216.2. ##Evidence-Data-START## Transcript exon combination :: BU599327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTATT AACAAGTAAA 
GGTGACGCGT GGGCCAAGTA CATGGCAGAA GTGAAAAAGT ACAAAGCTCA CCAGTGCGGT 
GACGATGATA AAACTCGGCC CCTGGTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001316667.1
CDS	119..571
Translation	MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQSAAAAGPGDPKRKGGPGSTLSFVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK

Target ORF information:

RefSeq Version	NM_001329738.1
Organism	Homo sapiens(human)
Definition	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001329738.1

ORF Insert Sequence:

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTATT AACAAGTAAA 
GGTGACGCGT GGGCCAAGTA CATGGCAGAA GTGAAAAAGT ACAAAGCTCA CCAGTGCGGT 
GACGATGATA AAACTCGGCC CCTGGTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIR ( NM_001329738.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001316667.1 Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu100591
Clone ID Related Accession (Same CDS sequence)	NM_001329738.1 , NM_001329738.2
Accession Version	NM_001329738.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559145600000
Organism	Homo sapiens(human)
Product	telomerase RNA component interacting RNase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ668685.1, BU599327.1 and BC000216.2. On May 31, 2019 this sequence version replaced NM_001329738.1. ##Evidence-Data-START## Transcript exon combination :: BU599327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTATT AACAAGTAAA 
GGTGACGCGT GGGCCAAGTA CATGGCAGAA GTGAAAAAGT ACAAAGCTCA CCAGTGCGGT 
GACGATGATA AAACTCGGCC CCTGGTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001316667.1
CDS	28..480
Translation	MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQSAAAAGPGDPKRKGGPGSTLSFVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK

Target ORF information:

RefSeq Version	NM_001329738.2
Organism	Homo sapiens(human)
Definition	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001329738.2

ORF Insert Sequence:

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTATT AACAAGTAAA 
GGTGACGCGT GGGCCAAGTA CATGGCAGAA GTGAAAAAGT ACAAAGCTCA CCAGTGCGGT 
GACGATGATA AAACTCGGCC CCTGGTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIR ( NM_024038.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_076943.1 Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29817
Clone ID Related Accession (Same CDS sequence)	NM_024038.4 , NM_024038.2 , NM_024038.3
Accession Version	NM_024038.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556640000000
Organism	Homo sapiens(human)
Product	telomerase RNA component interacting RNase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC000216.2. On Nov 22, 2018 this sequence version replaced NM_024038.3. Transcript Variant: This variant (1) encodes the longest protein (1). ##Evidence-Data-START## Transcript exon combination :: BC000216.2, BM925747.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000242784.5/ ENSP00000242784.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTGGG CAAACGCAGA 
GGCGGGAACA AACTAGCCCT CAAGACGGGA ATAGTAGCCA AGAAGCAGAA GACGGAGGAT 
GAGGTATTAA CAAGTAAAGG TGACGCGTGG GCCAAGTACA TGGCAGAAGT GAAAAAGTAC 
AAAGCTCACC AGTGCGGTGA CGATGATAAA ACTCGGCCCC TGGTGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076943.1
CDS	28..558
Translation	MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQSAAAAGPGDPKRKGGPGSTLSFVGKRRGGNKLALKTGIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK

Target ORF information:

RefSeq Version	NM_024038.4
Organism	Homo sapiens(human)
Definition	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024038.4

ORF Insert Sequence:

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTGGG CAAACGCAGA 
GGCGGGAACA AACTAGCCCT CAAGACGGGA ATAGTAGCCA AGAAGCAGAA GACGGAGGAT 
GAGGTATTAA CAAGTAAAGG TGACGCGTGG GCCAAGTACA TGGCAGAAGT GAAAAAGTAC 
AAAGCTCACC AGTGCGGTGA CGATGATAAA ACTCGGCCCC TGGTGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIR ( NM_024038.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_076943.1 Homo sapiens chromosome 19 open reading frame 43 (C19orf43), mRNA.

Price & Availability↑

CloneID	OHu29817
Clone ID Related Accession (Same CDS sequence)	NM_024038.4 , NM_024038.2 , NM_024038.3
Accession Version	NM_024038.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426262400000
Organism	Homo sapiens(Human)
Product	uncharacterized protein C19orf43
Comment

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTGGG CAAACGCAGA 
GGCGGGAACA AACTAGCCCT CAAGACGGGA ATAGTAGCCA AGAAGCAGAA GACGGAGGAT 
GAGGTATTAA CAAGTAAAGG TGACGCGTGG GCCAAGTACA TGGCAGAAGT GAAAAAGTAC 
AAAGCTCACC AGTGCGGTGA CGATGATAAA ACTCGGCCCC TGGTGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076943.1
Translation	MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQSAAAAGPGDPKRKGGPGSTLSFVGKRRGGNKLALKTGIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK

Target ORF information:

RefSeq Version	NM_024038.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens chromosome 19 open reading frame 43 (C19orf43), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024038.2

ORF Insert Sequence:

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTGGG CAAACGCAGA 
GGCGGGAACA AACTAGCCCT CAAGACGGGA ATAGTAGCCA AGAAGCAGAA GACGGAGGAT 
GAGGTATTAA CAAGTAAAGG TGACGCGTGG GCCAAGTACA TGGCAGAAGT GAAAAAGTAC 
AAAGCTCACC AGTGCGGTGA CGATGATAAA ACTCGGCCCC TGGTGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIR ( NM_024038.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_076943.1 Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 1, mRNA.

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CloneID	OHu29817
Clone ID Related Accession (Same CDS sequence)	NM_024038.4 , NM_024038.2 , NM_024038.3
Accession Version	NM_024038.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1511884800000
Organism	Homo sapiens(human)
Product	telomerase RNA component interacting RNase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL559579.3, BQ668685.1 and BC000216.2. On Jul 27, 2016 this sequence version replaced NM_024038.2. Transcript Variant: This variant (1) encodes the longest protein (1). ##Evidence-Data-START## Transcript exon combination :: SRR1163655.202914.1, SRR1163655.85889.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTGGG CAAACGCAGA 
GGCGGGAACA AACTAGCCCT CAAGACGGGA ATAGTAGCCA AGAAGCAGAA GACGGAGGAT 
GAGGTATTAA CAAGTAAAGG TGACGCGTGG GCCAAGTACA TGGCAGAAGT GAAAAAGTAC 
AAAGCTCACC AGTGCGGTGA CGATGATAAA ACTCGGCCCC TGGTGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076943.1
CDS	119..649
Translation	MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQSAAAAGPGDPKRKGGPGSTLSFVGKRRGGNKLALKTGIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK

Target ORF information:

RefSeq Version	NM_024038.3
Organism	Homo sapiens(human)
Definition	Homo sapiens telomerase RNA component interacting RNase (TRIR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024038.3

ORF Insert Sequence:

ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CAGGGCCGGG AGGCTCCGGG CCCCGCGGGC 
GGTGGCGGTG GCGGGAGCCG TTGGGCTGAG TCGGGATCGG GGACGTCGCC CGAGAGCGGG 
GACGAGGAGG TGTCGGGCGC GGGTTCGAGC CCGGTGTCGG GCGGCGTGAA CTTGTTCGCC 
AACGACGGCA GCTTCCTGGA GCTGTTCAAG CGGAAGATGG AGGAGGAGCA GCGGCAGCGG 
CAGGAGGAGC CGCCCCCGGG TCCGCAGCGA CCCGACCAGT CGGCCGCCGC CGCTGGCCCC 
GGGGATCCGA AGAGGAAGGG CGGTCCGGGC TCCACACTTA GCTTCGTGGG CAAACGCAGA 
GGCGGGAACA AACTAGCCCT CAAGACGGGA ATAGTAGCCA AGAAGCAGAA GACGGAGGAT 
GAGGTATTAA CAAGTAAAGG TGACGCGTGG GCCAAGTACA TGGCAGAAGT GAAAAAGTAC 
AAAGCTCACC AGTGCGGTGA CGATGATAAA ACTCGGCCCC TGGTGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of an RNase that preferentially cleaves A/G nucleotides.
Scientific reports745207(2017 03)
Xie J,Chen Z,Zhang X,Chen H,Guan W

Dynamic protein-protein interaction wiring of the human spliceosome.
Molecular cell45(4)567-80(2012 Feb)
Hegele A,Kamburov A,Grossmann A,Sourlis C,Wowro S,Weimann M,Will CL,Pena V,Lührmann R,Stelzl U

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TRIR cDNA ORF clone, Homo sapiens(human)

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