TULP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TULP1
Entrez Gene ID	7287
Full Name	tubby like protein 1
Synonyms	LCA15,RP14,TUBL1
General protein information	Preferred Names tubby like protein 1 Names tubby-related protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.31
Summary	This gene encodes a member of the tubby-like gene family (TULPs). Members of this family have been identified in plants, vertebrates, and invertebrates. TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. The protein encoded by this gene is thought to play a role in the physiology of photoreceptors. Mutations in this gene are associated with recessive juvenile retinitis pigmentosa and Leber congenital amaurosis-15. [provided by RefSeq, Nov 2016].
Disorder MIM:	602280
Disorder Html:	Retinitis pigmentosa 14, 600132 (3); Leber congenital amaurosis 15, 613843 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_003322.4	NP_003313.3	tubby-related protein 1 isoform 1
NM_001289395.1	NP_001276324.1	tubby-related protein 1 isoform 2
NM_003322.5	NP_003313.3	tubby-related protein 1 isoform 1
NM_003322.6	NP_003313.3	tubby-related protein 1 isoform 1
NM_001289395.2	NP_001276324.1	tubby-related protein 1 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TULP1	XP_001172351.1
Macaca mulatta (Rhesus monkey)	TULP1	XP_001111988.2
Gallus gallus (chicken)	TULP1	NP_989946.1
Canis lupus familiaris (dog)	TULP1	XP_538879.3
Mus musculus (house mouse)	Tulp1	NP_067453.1
Bos taurus (cattle)	TULP1	NP_001193657.1
Homo sapiens (human)	TULP1	NP_003313.3
Rattus norvegicus (Norway rat)	Tulp1	NP_001101112.1
Xenopus tropicalis (tropical clawed frog)	tulp1	NP_001016482.1

Gene Ontology
Bibliography

Related articles in PubMed

TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR).
Lobo GP, Ebke LA, Au A, Hagstrom SA
Advances in experimental medicine and biology854223-30(2016)

Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration.
Lobo GP, Au A, Kiser PD, Hagstrom SA
PloS one11(3)e0151806(2016)

Pathogenic mutations in TULP1 responsible for retinitis pigmentosa identified in consanguineous familial cases.
Ullah I, Kabir F, Iqbal M, Gottsch CB, Naeem MA, Assir MZ, Khan SN, Akram J, Riazuddin S, Ayyagari R, Hejtmancik JF, Riazuddin SA
Molecular vision22797-815(2016)

A TULP1 founder mutation, p.Gln301*, underlies a recognisable congenital rod-cone dystrophy phenotype on the Arabian Peninsula.
Khan AO, Bergmann C, Eisenberger T, Bolz HJ
The British journal of ophthalmology99(4)488-92(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TULP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TULP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16922	NM_001289395.2 Latest version!	Homo sapiens TUB like protein 1 (TULP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu21506	NM_003322.6 Latest version!	Homo sapiens TUB like protein 1 (TULP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$321.30 $459.00
View Old Accession Versions >>
OHu21506	NM_003322.4	Homo sapiens tubby like protein 1 (TULP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$321.30 $459.00
OHu21506	NM_003322.5	Homo sapiens tubby like protein 1 (TULP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$321.30 $459.00
OHu16922	NM_001289395.1	Homo sapiens tubby like protein 1 (TULP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TULP1 ( NM_001289395.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276324.1 Homo sapiens tubby like protein 1 (TULP1), transcript variant 2, mRNA.

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CloneID	OHu16922
Clone ID Related Accession (Same CDS sequence)	NM_001289395.1 , NM_001289395.2
Accession Version	NM_001289395.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550851200000
Organism	Homo sapiens(human)
Product	tubby-related protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB593123.1, BC032714.1, CN355966.1 and BC065261.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065261.1, BC032714.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG AGGAGGAGGA GGAAGAGGAG GACGAGGAGG ACGAGGAAGA GGAGGCAGAG 
GAAAAGAAAG AGAAAATCCT TCTGCCTCCC AAGAAGCCCC TGAGAGAGAA GAGCTCCGCA 
GACCTGAAGG AGAGGAGGGC CAAGGCCCAG GGCCCAAGGG GAGACCTGGG AAGCCCTGAC 
CCCCCACCGA AACCTCTGCG TGTTAGGAAT AAGGAAGCTC CAGCAGGGGA GGGGACCAAG 
ATGAGAAAGA CCAAGAAGAA AGGGTCTGGG GAGGCCGACA AGGACCCCTC AGGGAGCCCA 
GCCAGTGCGA GGAAGAGCCC AGCAGCCATG TTTCTGGTTG GGGAAGGCAG TCCTGACAAG 
AAAGCCCTGA AGAAGAAAGG CACTCCCAAA GGCGCGAGGA AGGAGGAAGA AGAGGAGGAG 
GAGGCAGCTA CGGTGATAAA GAAGAGCAAT CAAAAGGGCA AAGCCAAAGG AAAAGGCAAA 
AAGAAAGCGA AGGAGGAGAG GGCCCCGTCT CCCCCCGTGG AGGTGGACGA ACCCCGGGAG 
TTTGTGCTCC GGCCTGCCCC CCAGGGCCGC ACGGTGCGCT GCCGGCTGAC CCGGGACAAA 
AAGGGCATGG ATCGAGGCAT GTATCCCTCC TACTTCCTGC ACCTGGACAC GGAGAAGAAG 
GTGTTCCTCT TGGCTGGCAG GAAACGAAAA CGGAGCAAGA CAGCCAATTA CCTCATCTCC 
ATCGACCCTA CCAATCTGTC CCGAGGAGGG GAGAATTTCA TCGGGAAGCT GAGGTCCAAC 
CTCCTGGGGA ACCGCTTCAC GGTCTTTGAC AACGGGCAGA ACCCACAGCG TGGGTACAGC 
ACTAATGTGG CAAGCCTTCG GCAGGAGCTG GCAGCTGTGA TCTATGAAAC CAACGTGCTG 
GGCTTCCGTG GCCCCCGGCG CATGACCGTC ATCATTCCTG GCATGAGTGC GGAGAACGAG 
AGGGTCCCCA TCCGGCCCCG AAATGCTAGT GACGGCCTGC TGGTGCGCTG GCAGAACAAG 
ACGCTGGAGA GCCTCATAGA ACTGCACAAC AAGCCACCTG TCTGGAACGA TGACAGTGGC 
TCCTACACCC TCAACTTCCA AGGCCGGGTC ACCCAGGCCT CAGTCAAGAA CTTCCAGATT 
GTCCACGCTG ATGACCCCGA CTATATCGTG CTGCAGTTCG GCCGCGTGGC GGAGGACGCC 
TTCACCCTAG ACTACCGGTA CCCGCTGTGC GCCCTGCAGG CCTTCGCCAT CGCCCTCTCC 
AGTTTCGACG GGAAGCTGGC CTGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276324.1
CDS	45..1514
Translation	MPLRDETLREVWASDSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPGEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMYPSYFLHLDTEKKVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRFTVFDNGQNPQRGYSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLACE

Target ORF information:

RefSeq Version	NM_001289395.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tubby like protein 1 (TULP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289395.1

ORF Insert Sequence:

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG AGGAGGAGGA GGAAGAGGAG GACGAGGAGG ACGAGGAAGA GGAGGCAGAG 
GAAAAGAAAG AGAAAATCCT TCTGCCTCCC AAGAAGCCCC TGAGAGAGAA GAGCTCCGCA 
GACCTGAAGG AGAGGAGGGC CAAGGCCCAG GGCCCAAGGG GAGACCTGGG AAGCCCTGAC 
CCCCCACCGA AACCTCTGCG TGTTAGGAAT AAGGAAGCTC CAGCAGGGGA GGGGACCAAG 
ATGAGAAAGA CCAAGAAGAA AGGGTCTGGG GAGGCCGACA AGGACCCCTC AGGGAGCCCA 
GCCAGTGCGA GGAAGAGCCC AGCAGCCATG TTTCTGGTTG GGGAAGGCAG TCCTGACAAG 
AAAGCCCTGA AGAAGAAAGG CACTCCCAAA GGCGCGAGGA AGGAGGAAGA AGAGGAGGAG 
GAGGCAGCTA CGGTGATAAA GAAGAGCAAT CAAAAGGGCA AAGCCAAAGG AAAAGGCAAA 
AAGAAAGCGA AGGAGGAGAG GGCCCCGTCT CCCCCCGTGG AGGTGGACGA ACCCCGGGAG 
TTTGTGCTCC GGCCTGCCCC CCAGGGCCGC ACGGTGCGCT GCCGGCTGAC CCGGGACAAA 
AAGGGCATGG ATCGAGGCAT GTATCCCTCC TACTTCCTGC ACCTGGACAC GGAGAAGAAG 
GTGTTCCTCT TGGCTGGCAG GAAACGAAAA CGGAGCAAGA CAGCCAATTA CCTCATCTCC 
ATCGACCCTA CCAATCTGTC CCGAGGAGGG GAGAATTTCA TCGGGAAGCT GAGGTCCAAC 
CTCCTGGGGA ACCGCTTCAC GGTCTTTGAC AACGGGCAGA ACCCACAGCG TGGGTACAGC 
ACTAATGTGG CAAGCCTTCG GCAGGAGCTG GCAGCTGTGA TCTATGAAAC CAACGTGCTG 
GGCTTCCGTG GCCCCCGGCG CATGACCGTC ATCATTCCTG GCATGAGTGC GGAGAACGAG 
AGGGTCCCCA TCCGGCCCCG AAATGCTAGT GACGGCCTGC TGGTGCGCTG GCAGAACAAG 
ACGCTGGAGA GCCTCATAGA ACTGCACAAC AAGCCACCTG TCTGGAACGA TGACAGTGGC 
TCCTACACCC TCAACTTCCA AGGCCGGGTC ACCCAGGCCT CAGTCAAGAA CTTCCAGATT 
GTCCACGCTG ATGACCCCGA CTATATCGTG CTGCAGTTCG GCCGCGTGGC GGAGGACGCC 
TTCACCCTAG ACTACCGGTA CCCGCTGTGC GCCCTGCAGG CCTTCGCCAT CGCCCTCTCC 
AGTTTCGACG GGAAGCTGGC CTGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TULP1 ( NM_001289395.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276324.1 Homo sapiens TUB like protein 1 (TULP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16922
Clone ID Related Accession (Same CDS sequence)	NM_001289395.1 , NM_001289395.2
Accession Version	NM_001289395.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564675200000
Organism	Homo sapiens(human)
Product	tubby-related protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB593123.1, BC032714.1, CN355966.1 and BC065261.1. On Jun 1, 2019 this sequence version replaced NM_001289395.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065261.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG AGGAGGAGGA GGAAGAGGAG GACGAGGAGG ACGAGGAAGA GGAGGCAGAG 
GAAAAGAAAG AGAAAATCCT TCTGCCTCCC AAGAAGCCCC TGAGAGAGAA GAGCTCCGCA 
GACCTGAAGG AGAGGAGGGC CAAGGCCCAG GGCCCAAGGG GAGACCTGGG AAGCCCTGAC 
CCCCCACCGA AACCTCTGCG TGTTAGGAAT AAGGAAGCTC CAGCAGGGGA GGGGACCAAG 
ATGAGAAAGA CCAAGAAGAA AGGGTCTGGG GAGGCCGACA AGGACCCCTC AGGGAGCCCA 
GCCAGTGCGA GGAAGAGCCC AGCAGCCATG TTTCTGGTTG GGGAAGGCAG TCCTGACAAG 
AAAGCCCTGA AGAAGAAAGG CACTCCCAAA GGCGCGAGGA AGGAGGAAGA AGAGGAGGAG 
GAGGCAGCTA CGGTGATAAA GAAGAGCAAT CAAAAGGGCA AAGCCAAAGG AAAAGGCAAA 
AAGAAAGCGA AGGAGGAGAG GGCCCCGTCT CCCCCCGTGG AGGTGGACGA ACCCCGGGAG 
TTTGTGCTCC GGCCTGCCCC CCAGGGCCGC ACGGTGCGCT GCCGGCTGAC CCGGGACAAA 
AAGGGCATGG ATCGAGGCAT GTATCCCTCC TACTTCCTGC ACCTGGACAC GGAGAAGAAG 
GTGTTCCTCT TGGCTGGCAG GAAACGAAAA CGGAGCAAGA CAGCCAATTA CCTCATCTCC 
ATCGACCCTA CCAATCTGTC CCGAGGAGGG GAGAATTTCA TCGGGAAGCT GAGGTCCAAC 
CTCCTGGGGA ACCGCTTCAC GGTCTTTGAC AACGGGCAGA ACCCACAGCG TGGGTACAGC 
ACTAATGTGG CAAGCCTTCG GCAGGAGCTG GCAGCTGTGA TCTATGAAAC CAACGTGCTG 
GGCTTCCGTG GCCCCCGGCG CATGACCGTC ATCATTCCTG GCATGAGTGC GGAGAACGAG 
AGGGTCCCCA TCCGGCCCCG AAATGCTAGT GACGGCCTGC TGGTGCGCTG GCAGAACAAG 
ACGCTGGAGA GCCTCATAGA ACTGCACAAC AAGCCACCTG TCTGGAACGA TGACAGTGGC 
TCCTACACCC TCAACTTCCA AGGCCGGGTC ACCCAGGCCT CAGTCAAGAA CTTCCAGATT 
GTCCACGCTG ATGACCCCGA CTATATCGTG CTGCAGTTCG GCCGCGTGGC GGAGGACGCC 
TTCACCCTAG ACTACCGGTA CCCGCTGTGC GCCCTGCAGG CCTTCGCCAT CGCCCTCTCC 
AGTTTCGACG GGAAGCTGGC CTGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276324.1
CDS	39..1508
Translation	MPLRDETLREVWASDSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPGEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMYPSYFLHLDTEKKVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRFTVFDNGQNPQRGYSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLACE

Target ORF information:

RefSeq Version	NM_001289395.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TUB like protein 1 (TULP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289395.2

ORF Insert Sequence:

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG AGGAGGAGGA GGAAGAGGAG GACGAGGAGG ACGAGGAAGA GGAGGCAGAG 
GAAAAGAAAG AGAAAATCCT TCTGCCTCCC AAGAAGCCCC TGAGAGAGAA GAGCTCCGCA 
GACCTGAAGG AGAGGAGGGC CAAGGCCCAG GGCCCAAGGG GAGACCTGGG AAGCCCTGAC 
CCCCCACCGA AACCTCTGCG TGTTAGGAAT AAGGAAGCTC CAGCAGGGGA GGGGACCAAG 
ATGAGAAAGA CCAAGAAGAA AGGGTCTGGG GAGGCCGACA AGGACCCCTC AGGGAGCCCA 
GCCAGTGCGA GGAAGAGCCC AGCAGCCATG TTTCTGGTTG GGGAAGGCAG TCCTGACAAG 
AAAGCCCTGA AGAAGAAAGG CACTCCCAAA GGCGCGAGGA AGGAGGAAGA AGAGGAGGAG 
GAGGCAGCTA CGGTGATAAA GAAGAGCAAT CAAAAGGGCA AAGCCAAAGG AAAAGGCAAA 
AAGAAAGCGA AGGAGGAGAG GGCCCCGTCT CCCCCCGTGG AGGTGGACGA ACCCCGGGAG 
TTTGTGCTCC GGCCTGCCCC CCAGGGCCGC ACGGTGCGCT GCCGGCTGAC CCGGGACAAA 
AAGGGCATGG ATCGAGGCAT GTATCCCTCC TACTTCCTGC ACCTGGACAC GGAGAAGAAG 
GTGTTCCTCT TGGCTGGCAG GAAACGAAAA CGGAGCAAGA CAGCCAATTA CCTCATCTCC 
ATCGACCCTA CCAATCTGTC CCGAGGAGGG GAGAATTTCA TCGGGAAGCT GAGGTCCAAC 
CTCCTGGGGA ACCGCTTCAC GGTCTTTGAC AACGGGCAGA ACCCACAGCG TGGGTACAGC 
ACTAATGTGG CAAGCCTTCG GCAGGAGCTG GCAGCTGTGA TCTATGAAAC CAACGTGCTG 
GGCTTCCGTG GCCCCCGGCG CATGACCGTC ATCATTCCTG GCATGAGTGC GGAGAACGAG 
AGGGTCCCCA TCCGGCCCCG AAATGCTAGT GACGGCCTGC TGGTGCGCTG GCAGAACAAG 
ACGCTGGAGA GCCTCATAGA ACTGCACAAC AAGCCACCTG TCTGGAACGA TGACAGTGGC 
TCCTACACCC TCAACTTCCA AGGCCGGGTC ACCCAGGCCT CAGTCAAGAA CTTCCAGATT 
GTCCACGCTG ATGACCCCGA CTATATCGTG CTGCAGTTCG GCCGCGTGGC GGAGGACGCC 
TTCACCCTAG ACTACCGGTA CCCGCTGTGC GCCCTGCAGG CCTTCGCCAT CGCCCTCTCC 
AGTTTCGACG GGAAGCTGGC CTGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TULP1 ( NM_003322.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003313.3 Homo sapiens tubby like protein 1 (TULP1), transcript variant 1, mRNA.

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CloneID	OHu21506
Clone ID Related Accession (Same CDS sequence)	NM_003322.4 , NM_003322.5 , NM_003322.6
Accession Version	NM_003322.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1629bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426262400000
Organism	Homo sapiens(Human)
Product	tubby-related protein 1 isoform 1
Comment

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG CTGGGCGGAC GGGGAGGCCG CGGGAGGAGC CTTCCCCAGA CCCAGCCCAG 
GCCCGGGCGC CGCAGACGGT CTACGCCAGG TTCCTCAGGG ACCCCGAGGC CAAGAAGCGC 
GACCCCCGGG AAACCTTTCT GGTAGCCCGT GCCCCAGACG CGGAGGACGA GGAGGAGGAG 
GAAGAGGAGG ACGAGGAGGA CGAGGAAGAG GAGGCAGAGG AAAAGAAAGA GAAAATCCTT 
CTGCCTCCCA AGAAGCCCCT GAGAGAGAAG AGCTCCGCAG ACCTGAAGGA GAGGAGGGCC 
AAGGCCCAGG GCCCAAGGGG AGACCTGGGA AGCCCTGACC CCCCACCGAA ACCTCTGCGT 
GTTAGGAATA AGGAAGCTCC AGCAGGGGAG GGGACCAAGA TGAGAAAGAC CAAGAAGAAA 
GGGTCTGGGG AGGCCGACAA GGACCCCTCA GGGAGCCCAG CCAGTGCGAG GAAGAGCCCA 
GCAGCCATGT TTCTGGTTGG GGAAGGCAGT CCTGACAAGA AAGCCCTGAA GAAGAAAGGC 
ACTCCCAAAG GCGCGAGGAA GGAGGAAGAA GAGGAGGAGG AGGCAGCTAC GGTGATAAAG 
AAGAGCAATC AAAAGGGCAA AGCCAAAGGA AAAGGCAAAA AGAAAGCGAA GGAGGAGAGG 
GCCCCGTCTC CCCCCGTGGA GGTGGACGAA CCCCGGGAGT TTGTGCTCCG GCCTGCCCCC 
CAGGGCCGCA CGGTGCGCTG CCGGCTGACC CGGGACAAAA AGGGCATGGA TCGAGGCATG 
TATCCCTCCT ACTTCCTGCA CCTGGACACG GAGAAGAAGG TGTTCCTCTT GGCTGGCAGG 
AAACGAAAAC GGAGCAAGAC AGCCAATTAC CTCATCTCCA TCGACCCTAC CAATCTGTCC 
CGAGGAGGGG AGAATTTCAT CGGGAAGCTG AGGTCCAACC TCCTGGGGAA CCGCTTCACG 
GTCTTTGACA ACGGGCAGAA CCCACAGCGT GGGTACAGCA CTAATGTGGC AAGCCTTCGG 
CAGGAGCTGG CAGCTGTGAT CTATGAAACC AACGTGCTGG GCTTCCGTGG CCCCCGGCGC 
ATGACCGTCA TCATTCCTGG CATGAGTGCG GAGAACGAGA GGGTCCCCAT CCGGCCCCGA 
AATGCTAGTG ACGGCCTGCT GGTGCGCTGG CAGAACAAGA CGCTGGAGAG CCTCATAGAA 
CTGCACAACA AGCCACCTGT CTGGAACGAT GACAGTGGCT CCTACACCCT CAACTTCCAA 
GGCCGGGTCA CCCAGGCCTC AGTCAAGAAC TTCCAGATTG TCCACGCTGA TGACCCCGAC 
TATATCGTGC TGCAGTTCGG CCGCGTGGCG GAGGACGCCT TCACCCTAGA CTACCGGTAC 
CCGCTGTGCG CCCTGCAGGC CTTCGCCATC GCCCTCTCCA GTTTCGACGG GAAGCTGGCC 
TGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_003313.3

Translation

MPLRDETLREVWASDSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPGAGRTGRPREEPSPDPAQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMYPSYFLHLDTEKKVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRFTVFDNGQNPQRGYSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLACE

Target ORF information:

RefSeq Version	NM_003322.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens tubby like protein 1 (TULP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003322.4

ORF Insert Sequence:

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG CTGGGCGGAC GGGGAGGCCG CGGGAGGAGC CTTCCCCAGA CCCAGCCCAG 
GCCCGGGCGC CGCAGACGGT CTACGCCAGG TTCCTCAGGG ACCCCGAGGC CAAGAAGCGC 
GACCCCCGGG AAACCTTTCT GGTAGCCCGT GCCCCAGACG CGGAGGACGA GGAGGAGGAG 
GAAGAGGAGG ACGAGGAGGA CGAGGAAGAG GAGGCAGAGG AAAAGAAAGA GAAAATCCTT 
CTGCCTCCCA AGAAGCCCCT GAGAGAGAAG AGCTCCGCAG ACCTGAAGGA GAGGAGGGCC 
AAGGCCCAGG GCCCAAGGGG AGACCTGGGA AGCCCTGACC CCCCACCGAA ACCTCTGCGT 
GTTAGGAATA AGGAAGCTCC AGCAGGGGAG GGGACCAAGA TGAGAAAGAC CAAGAAGAAA 
GGGTCTGGGG AGGCCGACAA GGACCCCTCA GGGAGCCCAG CCAGTGCGAG GAAGAGCCCA 
GCAGCCATGT TTCTGGTTGG GGAAGGCAGT CCTGACAAGA AAGCCCTGAA GAAGAAAGGC 
ACTCCCAAAG GCGCGAGGAA GGAGGAAGAA GAGGAGGAGG AGGCAGCTAC GGTGATAAAG 
AAGAGCAATC AAAAGGGCAA AGCCAAAGGA AAAGGCAAAA AGAAAGCGAA GGAGGAGAGG 
GCCCCGTCTC CCCCCGTGGA GGTGGACGAA CCCCGGGAGT TTGTGCTCCG GCCTGCCCCC 
CAGGGCCGCA CGGTGCGCTG CCGGCTGACC CGGGACAAAA AGGGCATGGA TCGAGGCATG 
TATCCCTCCT ACTTCCTGCA CCTGGACACG GAGAAGAAGG TGTTCCTCTT GGCTGGCAGG 
AAACGAAAAC GGAGCAAGAC AGCCAATTAC CTCATCTCCA TCGACCCTAC CAATCTGTCC 
CGAGGAGGGG AGAATTTCAT CGGGAAGCTG AGGTCCAACC TCCTGGGGAA CCGCTTCACG 
GTCTTTGACA ACGGGCAGAA CCCACAGCGT GGGTACAGCA CTAATGTGGC AAGCCTTCGG 
CAGGAGCTGG CAGCTGTGAT CTATGAAACC AACGTGCTGG GCTTCCGTGG CCCCCGGCGC 
ATGACCGTCA TCATTCCTGG CATGAGTGCG GAGAACGAGA GGGTCCCCAT CCGGCCCCGA 
AATGCTAGTG ACGGCCTGCT GGTGCGCTGG CAGAACAAGA CGCTGGAGAG CCTCATAGAA 
CTGCACAACA AGCCACCTGT CTGGAACGAT GACAGTGGCT CCTACACCCT CAACTTCCAA 
GGCCGGGTCA CCCAGGCCTC AGTCAAGAAC TTCCAGATTG TCCACGCTGA TGACCCCGAC 
TATATCGTGC TGCAGTTCGG CCGCGTGGCG GAGGACGCCT TCACCCTAGA CTACCGGTAC 
CCGCTGTGCG CCCTGCAGGC CTTCGCCATC GCCCTCTCCA GTTTCGACGG GAAGCTGGCC 
TGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TULP1 ( NM_003322.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003313.3 Homo sapiens tubby like protein 1 (TULP1), transcript variant 1, mRNA.

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CloneID	OHu21506
Clone ID Related Accession (Same CDS sequence)	NM_003322.4 , NM_003322.5 , NM_003322.6
Accession Version	NM_003322.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1629bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506960000000
Organism	Homo sapiens(human)
Product	tubby-related protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ426893.1, U82468.2, AL033519.42 and BC065261.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2016 this sequence version replaced NM_003322.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U82468.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG CTGGGCGGAC GGGGAGGCCG CGGGAGGAGC CTTCCCCAGA CCCAGCCCAG 
GCCCGGGCGC CGCAGACGGT CTACGCCAGG TTCCTCAGGG ACCCCGAGGC CAAGAAGCGC 
GACCCCCGGG AAACCTTTCT GGTAGCCCGT GCCCCAGACG CGGAGGACGA GGAGGAGGAG 
GAAGAGGAGG ACGAGGAGGA CGAGGAAGAG GAGGCAGAGG AAAAGAAAGA GAAAATCCTT 
CTGCCTCCCA AGAAGCCCCT GAGAGAGAAG AGCTCCGCAG ACCTGAAGGA GAGGAGGGCC 
AAGGCCCAGG GCCCAAGGGG AGACCTGGGA AGCCCTGACC CCCCACCGAA ACCTCTGCGT 
GTTAGGAATA AGGAAGCTCC AGCAGGGGAG GGGACCAAGA TGAGAAAGAC CAAGAAGAAA 
GGGTCTGGGG AGGCCGACAA GGACCCCTCA GGGAGCCCAG CCAGTGCGAG GAAGAGCCCA 
GCAGCCATGT TTCTGGTTGG GGAAGGCAGT CCTGACAAGA AAGCCCTGAA GAAGAAAGGC 
ACTCCCAAAG GCGCGAGGAA GGAGGAAGAA GAGGAGGAGG AGGCAGCTAC GGTGATAAAG 
AAGAGCAATC AAAAGGGCAA AGCCAAAGGA AAAGGCAAAA AGAAAGCGAA GGAGGAGAGG 
GCCCCGTCTC CCCCCGTGGA GGTGGACGAA CCCCGGGAGT TTGTGCTCCG GCCTGCCCCC 
CAGGGCCGCA CGGTGCGCTG CCGGCTGACC CGGGACAAAA AGGGCATGGA TCGAGGCATG 
TATCCCTCCT ACTTCCTGCA CCTGGACACG GAGAAGAAGG TGTTCCTCTT GGCTGGCAGG 
AAACGAAAAC GGAGCAAGAC AGCCAATTAC CTCATCTCCA TCGACCCTAC CAATCTGTCC 
CGAGGAGGGG AGAATTTCAT CGGGAAGCTG AGGTCCAACC TCCTGGGGAA CCGCTTCACG 
GTCTTTGACA ACGGGCAGAA CCCACAGCGT GGGTACAGCA CTAATGTGGC AAGCCTTCGG 
CAGGAGCTGG CAGCTGTGAT CTATGAAACC AACGTGCTGG GCTTCCGTGG CCCCCGGCGC 
ATGACCGTCA TCATTCCTGG CATGAGTGCG GAGAACGAGA GGGTCCCCAT CCGGCCCCGA 
AATGCTAGTG ACGGCCTGCT GGTGCGCTGG CAGAACAAGA CGCTGGAGAG CCTCATAGAA 
CTGCACAACA AGCCACCTGT CTGGAACGAT GACAGTGGCT CCTACACCCT CAACTTCCAA 
GGCCGGGTCA CCCAGGCCTC AGTCAAGAAC TTCCAGATTG TCCACGCTGA TGACCCCGAC 
TATATCGTGC TGCAGTTCGG CCGCGTGGCG GAGGACGCCT TCACCCTAGA CTACCGGTAC 
CCGCTGTGCG CCCTGCAGGC CTTCGCCATC GCCCTCTCCA GTTTCGACGG GAAGCTGGCC 
TGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003313.3
CDS	81..1709
Translation	MPLRDETLREVWASDSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPGAGRTGRPREEPSPDPAQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMYPSYFLHLDTEKKVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRFTVFDNGQNPQRGYSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLACE

Target ORF information:

RefSeq Version	NM_003322.5
Organism	Homo sapiens(human)
Definition	Homo sapiens tubby like protein 1 (TULP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003322.5

ORF Insert Sequence:

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG CTGGGCGGAC GGGGAGGCCG CGGGAGGAGC CTTCCCCAGA CCCAGCCCAG 
GCCCGGGCGC CGCAGACGGT CTACGCCAGG TTCCTCAGGG ACCCCGAGGC CAAGAAGCGC 
GACCCCCGGG AAACCTTTCT GGTAGCCCGT GCCCCAGACG CGGAGGACGA GGAGGAGGAG 
GAAGAGGAGG ACGAGGAGGA CGAGGAAGAG GAGGCAGAGG AAAAGAAAGA GAAAATCCTT 
CTGCCTCCCA AGAAGCCCCT GAGAGAGAAG AGCTCCGCAG ACCTGAAGGA GAGGAGGGCC 
AAGGCCCAGG GCCCAAGGGG AGACCTGGGA AGCCCTGACC CCCCACCGAA ACCTCTGCGT 
GTTAGGAATA AGGAAGCTCC AGCAGGGGAG GGGACCAAGA TGAGAAAGAC CAAGAAGAAA 
GGGTCTGGGG AGGCCGACAA GGACCCCTCA GGGAGCCCAG CCAGTGCGAG GAAGAGCCCA 
GCAGCCATGT TTCTGGTTGG GGAAGGCAGT CCTGACAAGA AAGCCCTGAA GAAGAAAGGC 
ACTCCCAAAG GCGCGAGGAA GGAGGAAGAA GAGGAGGAGG AGGCAGCTAC GGTGATAAAG 
AAGAGCAATC AAAAGGGCAA AGCCAAAGGA AAAGGCAAAA AGAAAGCGAA GGAGGAGAGG 
GCCCCGTCTC CCCCCGTGGA GGTGGACGAA CCCCGGGAGT TTGTGCTCCG GCCTGCCCCC 
CAGGGCCGCA CGGTGCGCTG CCGGCTGACC CGGGACAAAA AGGGCATGGA TCGAGGCATG 
TATCCCTCCT ACTTCCTGCA CCTGGACACG GAGAAGAAGG TGTTCCTCTT GGCTGGCAGG 
AAACGAAAAC GGAGCAAGAC AGCCAATTAC CTCATCTCCA TCGACCCTAC CAATCTGTCC 
CGAGGAGGGG AGAATTTCAT CGGGAAGCTG AGGTCCAACC TCCTGGGGAA CCGCTTCACG 
GTCTTTGACA ACGGGCAGAA CCCACAGCGT GGGTACAGCA CTAATGTGGC AAGCCTTCGG 
CAGGAGCTGG CAGCTGTGAT CTATGAAACC AACGTGCTGG GCTTCCGTGG CCCCCGGCGC 
ATGACCGTCA TCATTCCTGG CATGAGTGCG GAGAACGAGA GGGTCCCCAT CCGGCCCCGA 
AATGCTAGTG ACGGCCTGCT GGTGCGCTGG CAGAACAAGA CGCTGGAGAG CCTCATAGAA 
CTGCACAACA AGCCACCTGT CTGGAACGAT GACAGTGGCT CCTACACCCT CAACTTCCAA 
GGCCGGGTCA CCCAGGCCTC AGTCAAGAAC TTCCAGATTG TCCACGCTGA TGACCCCGAC 
TATATCGTGC TGCAGTTCGG CCGCGTGGCG GAGGACGCCT TCACCCTAGA CTACCGGTAC 
CCGCTGTGCG CCCTGCAGGC CTTCGCCATC GCCCTCTCCA GTTTCGACGG GAAGCTGGCC 
TGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TULP1 ( NM_003322.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_003313.3 Homo sapiens TUB like protein 1 (TULP1), transcript variant 1, mRNA.

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CloneID	OHu21506
Clone ID Related Accession (Same CDS sequence)	NM_003322.4 , NM_003322.5 , NM_003322.6
Accession Version	NM_003322.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1629bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566316800000
Organism	Homo sapiens(human)
Product	tubby-related protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ426893.1, U82468.2, AL033519.42 and BC065261.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_003322.5. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U82468.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000229771.11/ ENSP00000229771.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG CTGGGCGGAC GGGGAGGCCG CGGGAGGAGC CTTCCCCAGA CCCAGCCCAG 
GCCCGGGCGC CGCAGACGGT CTACGCCAGG TTCCTCAGGG ACCCCGAGGC CAAGAAGCGC 
GACCCCCGGG AAACCTTTCT GGTAGCCCGT GCCCCAGACG CGGAGGACGA GGAGGAGGAG 
GAAGAGGAGG ACGAGGAGGA CGAGGAAGAG GAGGCAGAGG AAAAGAAAGA GAAAATCCTT 
CTGCCTCCCA AGAAGCCCCT GAGAGAGAAG AGCTCCGCAG ACCTGAAGGA GAGGAGGGCC 
AAGGCCCAGG GCCCAAGGGG AGACCTGGGA AGCCCTGACC CCCCACCGAA ACCTCTGCGT 
GTTAGGAATA AGGAAGCTCC AGCAGGGGAG GGGACCAAGA TGAGAAAGAC CAAGAAGAAA 
GGGTCTGGGG AGGCCGACAA GGACCCCTCA GGGAGCCCAG CCAGTGCGAG GAAGAGCCCA 
GCAGCCATGT TTCTGGTTGG GGAAGGCAGT CCTGACAAGA AAGCCCTGAA GAAGAAAGGC 
ACTCCCAAAG GCGCGAGGAA GGAGGAAGAA GAGGAGGAGG AGGCAGCTAC GGTGATAAAG 
AAGAGCAATC AAAAGGGCAA AGCCAAAGGA AAAGGCAAAA AGAAAGCGAA GGAGGAGAGG 
GCCCCGTCTC CCCCCGTGGA GGTGGACGAA CCCCGGGAGT TTGTGCTCCG GCCTGCCCCC 
CAGGGCCGCA CGGTGCGCTG CCGGCTGACC CGGGACAAAA AGGGCATGGA TCGAGGCATG 
TATCCCTCCT ACTTCCTGCA CCTGGACACG GAGAAGAAGG TGTTCCTCTT GGCTGGCAGG 
AAACGAAAAC GGAGCAAGAC AGCCAATTAC CTCATCTCCA TCGACCCTAC CAATCTGTCC 
CGAGGAGGGG AGAATTTCAT CGGGAAGCTG AGGTCCAACC TCCTGGGGAA CCGCTTCACG 
GTCTTTGACA ACGGGCAGAA CCCACAGCGT GGGTACAGCA CTAATGTGGC AAGCCTTCGG 
CAGGAGCTGG CAGCTGTGAT CTATGAAACC AACGTGCTGG GCTTCCGTGG CCCCCGGCGC 
ATGACCGTCA TCATTCCTGG CATGAGTGCG GAGAACGAGA GGGTCCCCAT CCGGCCCCGA 
AATGCTAGTG ACGGCCTGCT GGTGCGCTGG CAGAACAAGA CGCTGGAGAG CCTCATAGAA 
CTGCACAACA AGCCACCTGT CTGGAACGAT GACAGTGGCT CCTACACCCT CAACTTCCAA 
GGCCGGGTCA CCCAGGCCTC AGTCAAGAAC TTCCAGATTG TCCACGCTGA TGACCCCGAC 
TATATCGTGC TGCAGTTCGG CCGCGTGGCG GAGGACGCCT TCACCCTAGA CTACCGGTAC 
CCGCTGTGCG CCCTGCAGGC CTTCGCCATC GCCCTCTCCA GTTTCGACGG GAAGCTGGCC 
TGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003313.3
CDS	39..1667
Translation	MPLRDETLREVWASDSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPGAGRTGRPREEPSPDPAQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMYPSYFLHLDTEKKVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRFTVFDNGQNPQRGYSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLACE

Target ORF information:

RefSeq Version	NM_003322.6
Organism	Homo sapiens(human)
Definition	Homo sapiens TUB like protein 1 (TULP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003322.6

ORF Insert Sequence:

ATGCCTCTGC GGGATGAAAC CCTCCGAGAG GTGTGGGCCT CTGACAGTGG GCATGAAGAA 
GAAAGCCTGA GCCCGGAGGC CCCGCGGCGC CCCAAACAGC GACCCGCCCC GGCACAGAGG 
CTAAGGAAGA AGAGGACGGA GGCCCCCGAA TCCCCCTGCC CCACGGGATC CAAGCCCCGG 
AAGCCCGGAG CTGGGCGGAC GGGGAGGCCG CGGGAGGAGC CTTCCCCAGA CCCAGCCCAG 
GCCCGGGCGC CGCAGACGGT CTACGCCAGG TTCCTCAGGG ACCCCGAGGC CAAGAAGCGC 
GACCCCCGGG AAACCTTTCT GGTAGCCCGT GCCCCAGACG CGGAGGACGA GGAGGAGGAG 
GAAGAGGAGG ACGAGGAGGA CGAGGAAGAG GAGGCAGAGG AAAAGAAAGA GAAAATCCTT 
CTGCCTCCCA AGAAGCCCCT GAGAGAGAAG AGCTCCGCAG ACCTGAAGGA GAGGAGGGCC 
AAGGCCCAGG GCCCAAGGGG AGACCTGGGA AGCCCTGACC CCCCACCGAA ACCTCTGCGT 
GTTAGGAATA AGGAAGCTCC AGCAGGGGAG GGGACCAAGA TGAGAAAGAC CAAGAAGAAA 
GGGTCTGGGG AGGCCGACAA GGACCCCTCA GGGAGCCCAG CCAGTGCGAG GAAGAGCCCA 
GCAGCCATGT TTCTGGTTGG GGAAGGCAGT CCTGACAAGA AAGCCCTGAA GAAGAAAGGC 
ACTCCCAAAG GCGCGAGGAA GGAGGAAGAA GAGGAGGAGG AGGCAGCTAC GGTGATAAAG 
AAGAGCAATC AAAAGGGCAA AGCCAAAGGA AAAGGCAAAA AGAAAGCGAA GGAGGAGAGG 
GCCCCGTCTC CCCCCGTGGA GGTGGACGAA CCCCGGGAGT TTGTGCTCCG GCCTGCCCCC 
CAGGGCCGCA CGGTGCGCTG CCGGCTGACC CGGGACAAAA AGGGCATGGA TCGAGGCATG 
TATCCCTCCT ACTTCCTGCA CCTGGACACG GAGAAGAAGG TGTTCCTCTT GGCTGGCAGG 
AAACGAAAAC GGAGCAAGAC AGCCAATTAC CTCATCTCCA TCGACCCTAC CAATCTGTCC 
CGAGGAGGGG AGAATTTCAT CGGGAAGCTG AGGTCCAACC TCCTGGGGAA CCGCTTCACG 
GTCTTTGACA ACGGGCAGAA CCCACAGCGT GGGTACAGCA CTAATGTGGC AAGCCTTCGG 
CAGGAGCTGG CAGCTGTGAT CTATGAAACC AACGTGCTGG GCTTCCGTGG CCCCCGGCGC 
ATGACCGTCA TCATTCCTGG CATGAGTGCG GAGAACGAGA GGGTCCCCAT CCGGCCCCGA 
AATGCTAGTG ACGGCCTGCT GGTGCGCTGG CAGAACAAGA CGCTGGAGAG CCTCATAGAA 
CTGCACAACA AGCCACCTGT CTGGAACGAT GACAGTGGCT CCTACACCCT CAACTTCCAA 
GGCCGGGTCA CCCAGGCCTC AGTCAAGAAC TTCCAGATTG TCCACGCTGA TGACCCCGAC 
TATATCGTGC TGCAGTTCGG CCGCGTGGCG GAGGACGCCT TCACCCTAGA CTACCGGTAC 
CCGCTGTGCG CCCTGCAGGC CTTCGCCATC GCCCTCTCCA GTTTCGACGG GAAGCTGGCC 
TGCGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR).
Advances in experimental medicine and biology854223-30(2016)
Lobo GP,Ebke LA,Au A,Hagstrom SA

Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration.
PloS one11(3)e0151806(2016)
Lobo GP,Au A,Kiser PD,Hagstrom SA

Pathogenic mutations in TULP1 responsible for retinitis pigmentosa identified in consanguineous familial cases.
Molecular vision22797-815(2016)
Ullah I,Kabir F,Iqbal M,Gottsch CB,Naeem MA,Assir MZ,Khan SN,Akram J,Riazuddin S,Ayyagari R,Hejtmancik JF,Riazuddin SA

A TULP1 founder mutation, p.Gln301*, underlies a recognisable congenital rod-cone dystrophy phenotype on the Arabian Peninsula.
The British journal of ophthalmology99(4)488-92(2015 Apr)
Khan AO,Bergmann C,Eisenberger T,Bolz HJ

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TULP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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