POLR1E cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	POLR1E
Entrez Gene ID	64425
Full Name	RNA polymerase I subunit E
Synonyms	PAF53,PRAF1
General protein information	Preferred Names RNA polymerase I subunit E Names DNA-directed RNA polymerase I subunit RPA49 DNA-directed RNA polymerase I subunit E RNA polymerase I subunit A49 RNA polymerase I-associated factor 53 polymerase (RNA) I associated factor 1 polymerase (RNA) I polypeptide E, 53kDa polymerase (RNA) I subunit E
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p13.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_022490.3	NP_071935.1	DNA-directed RNA polymerase I subunit RPA49 isoform 1
XM_005251547.2	XP_005251604.1	DNA-directed RNA polymerase I subunit RPA49 isoform X1
NM_022490.4	NP_071935.1	DNA-directed RNA polymerase I subunit RPA49 isoform 1
NM_001282766.1	NP_001269695.1	DNA-directed RNA polymerase I subunit RPA49 isoform 2
NM_022490.2	NP_071935.1	DNA-directed RNA polymerase I subunit RPA49 isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Polr1e	NP_001101408.1
Xenopus tropicalis (tropical clawed frog)	polr1e	NP_001120306.1
Gallus gallus (chicken)	POLR1E	XP_424416.3
Danio rerio (zebrafish)	polr1e	NP_001018540.1
Mus musculus (house mouse)	Polr1e	NP_073722.1
Homo sapiens (human)	POLR1E	NP_071935.1
Pan troglodytes (chimpanzee)	POLR1E	XP_001169824.1
Canis lupus familiaris (dog)	POLR1E	XP_531998.2
Bos taurus (cattle)	POLR1E	NP_001029580.1

Gene Ontology
Bibliography

Related articles in PubMed

Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7.
Chen S, Seiler J, Santiago-Reichelt M, Felbel K, Grummt I, Voit R
Molecular cell52(3)303-13(2013 Nov)

The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription.
Percipalle P, Fomproix N, Cavellán E, Voit R, Reimer G, Krüger T, Thyberg J, Scheer U, Grummt I, Farrants AK
EMBO reports7(5)525-30(2006 May)

Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.
Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M
Molecular and cellular biology24(14)6338-49(2004 Jul)

Regulation of ribosomal RNA synthesis during the final phases of porcine oocyte growth.
Bjerregaard B, Wrenzycki C, Philimonenko VV, Hozak P, Laurincik J, Niemann H, Motlik J, Maddox-Hyttel P
Biology of reproduction70(4)925-35(2004 Apr)

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G
Nature cell biology6(2)97-105(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following POLR1E gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POLR1E cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu108813	NM_022490.4 Latest version!	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu14186	NM_001282766.1 Latest version!	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu42823	XM_005251547.2 Latest version!	Homo sapiens polymerase (RNA) I subunit E (POLR1E), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu11924	NM_022490.3 Latest version!	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu11924	NM_022490.2	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POLR1E ( NM_022490.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071935.1 Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu108813
Clone ID Related Accession (Same CDS sequence)	NM_022490.4
Accession Version	NM_022490.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568390400000
Organism	Homo sapiens(human)
Product	DNA-directed RNA polymerase I subunit RPA49 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7. On Aug 31, 2019 this sequence version replaced NM_022490.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK023452.1, BC001337.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377798.9/ ENSP00000367029.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC 
CAGAGAGCTG TACTGGTCCA GTTCTCCAAC GGGAAGCTAC AGAGTCCAGG CAACATGCGC 
TTTACCTTGT ATGAGAACAA AGATTCCACC AACCCCAGGA AGAGGAATCA ACGGATCCTG 
GCAGCTGAAA CAGATAGGCT CTCCTATGTG GGAAACAATT TTGGGACTGG AGCCCTCAAA 
TGCAACACTT TGTGCAGGCA CTTTGTGGGA ATTTTGAACA AGACCTCTGG CCAAATGGAA 
GTATATGATG CTGAATTGTT CAACATGCAG CCACTATTTT CAGATGTATC AGTTGAGAGT 
GAACTGGCGC TAGAGAGTCA GACCAAAACT TACAGAGAAA AGATGGATTC TTGTATTGAA 
GCCTTTGGTA CCACCAAACA GAAGCGAGCT CTGAACACCA GGAGAATGAA CAGAGTTGGC 
AATGAATCTT TGAATCGTGC AGTGGCTAAA GCTGCAGAGA CTATCATTGA TACGAAGGGT 
GTGACTGCTC TGGTCAGCGA TGCTATCCAC AATGACTTGC AAGATGACTC CCTCTACCTT 
CCTCCCTGCT ATGATGATGC AGCCAAGCCT GAAGACGTGT ATAAATTTGA AGATCTTCTT 
TCCCCTGCGG AGTATGAAGC TCTTCAGAGC CCATCTGAAG CTTTCAGGAA CGTCACGTCA 
GAAGAAATAC TGAAGATGAT TGAGGAGAAC AGCCATTGCA CCTTTGTCAT AGAAGCGTTG 
AAGTCTTTGC CATCAGATGT GGAGAGCCGA GACCGCCAGG CCCGATGCAT ATGGTTTCTG 
GATACCCTCA TCAAATTTCG AGCTCATAGG GTAGTTAAGC GGAAAAGTGC TCTGGGACCT 
GGAGTTCCCC ACATCATCAA CACCAAACTG CTGAAGCACT TTACTTGCTT GACCTACAAC 
AATGGCAGAT TACGGAACTT AATTTCGGAT TCTATGAAGG CGAAGATTAC TGCATATGTG 
ATCATACTTG CCTTGCACAT ACATGACTTC CAAATTGACC TGACAGTGTT ACAGAGGGAC 
TTGAAGCTCA GTGAGAAAAG GATGATGGAG ATAGCCAAAG CCATGAGGCT GAAGATCTCC 
AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT GAAGAAGATC ACAAGCTGGG CACCCTGTCC 
CTCCCGCTGC CTCCAGCCCA GACCTCAGAC CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071935.1
CDS	101..1360
Translation	MAAEVLPSARWQYCGAPDGSQRAVLVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFSDVSVESELALESQTKTYREKMDSCIEAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAETIIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENSHCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGPGVPHIINTKLLKHFTCLTYNNGRLRNLISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGSEEDHKLGTLSLPLPPAQTSDRLAKRRKIT

Target ORF information:

RefSeq Version	NM_022490.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022490.4

ORF Insert Sequence:

ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC 
CAGAGAGCTG TACTGGTCCA GTTCTCCAAC GGGAAGCTAC AGAGTCCAGG CAACATGCGC 
TTTACCTTGT ATGAGAACAA AGATTCCACC AACCCCAGGA AGAGGAATCA ACGGATCCTG 
GCAGCTGAAA CAGATAGGCT CTCCTATGTG GGAAACAATT TTGGGACTGG AGCCCTCAAA 
TGCAACACTT TGTGCAGGCA CTTTGTGGGA ATTTTGAACA AGACCTCTGG CCAAATGGAA 
GTATATGATG CTGAATTGTT CAACATGCAG CCACTATTTT CAGATGTATC AGTTGAGAGT 
GAACTGGCGC TAGAGAGTCA GACCAAAACT TACAGAGAAA AGATGGATTC TTGTATTGAA 
GCCTTTGGTA CCACCAAACA GAAGCGAGCT CTGAACACCA GGAGAATGAA CAGAGTTGGC 
AATGAATCTT TGAATCGTGC AGTGGCTAAA GCTGCAGAGA CTATCATTGA TACGAAGGGT 
GTGACTGCTC TGGTCAGCGA TGCTATCCAC AATGACTTGC AAGATGACTC CCTCTACCTT 
CCTCCCTGCT ATGATGATGC AGCCAAGCCT GAAGACGTGT ATAAATTTGA AGATCTTCTT 
TCCCCTGCGG AGTATGAAGC TCTTCAGAGC CCATCTGAAG CTTTCAGGAA CGTCACGTCA 
GAAGAAATAC TGAAGATGAT TGAGGAGAAC AGCCATTGCA CCTTTGTCAT AGAAGCGTTG 
AAGTCTTTGC CATCAGATGT GGAGAGCCGA GACCGCCAGG CCCGATGCAT ATGGTTTCTG 
GATACCCTCA TCAAATTTCG AGCTCATAGG GTAGTTAAGC GGAAAAGTGC TCTGGGACCT 
GGAGTTCCCC ACATCATCAA CACCAAACTG CTGAAGCACT TTACTTGCTT GACCTACAAC 
AATGGCAGAT TACGGAACTT AATTTCGGAT TCTATGAAGG CGAAGATTAC TGCATATGTG 
ATCATACTTG CCTTGCACAT ACATGACTTC CAAATTGACC TGACAGTGTT ACAGAGGGAC 
TTGAAGCTCA GTGAGAAAAG GATGATGGAG ATAGCCAAAG CCATGAGGCT GAAGATCTCC 
AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT GAAGAAGATC ACAAGCTGGG CACCCTGTCC 
CTCCCGCTGC CTCCAGCCCA GACCTCAGAC CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POLR1E ( NM_001282766.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269695.1 Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14186
Clone ID Related Accession (Same CDS sequence)	NM_001282766.1
Accession Version	NM_001282766.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569254400000
Organism	Homo sapiens(human)
Product	DNA-directed RNA polymerase I subunit RPA49 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7, AK303167.1 and BC001337.1. On Sep 19, 2013 this sequence version replaced XM_005251548.1. Transcript Variant: This variant (2) uses an alternate exon the coding region which results in the use of downstream start codon compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK303167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGATGCTGA ATTGTTCAAC ATGCAGCCAC TATTTTCAGG TCTTTCACCA AGAAAGCAAA 
ATTATTTTCT GGAAAGAGCC AAGGACTTGT TTTCTAATCC TGTCTCTGCC ACTACCTGGT 
GAACTGACCT GGGATGTATC AGTTGAGAGT GAACTGGCGC TAGAGAGTCA GACCAAAACT 
TACAGAGAAA AGATGGATTC TTGTATTGAA GCCTTTGGTA CCACCAAACA GAAGCGAGCT 
CTGAACACCA GGAGAATGAA CAGAGTTGGC AATGAATCTT TGAATCGTGC AGTGGCTAAA 
GCTGCAGAGA CTATCATTGA TACGAAGGGT GTGACTGCTC TGGTCAGCGA TGCTATCCAC 
AATGACTTGC AAGATGACTC CCTCTACCTT CCTCCCTGCT ATGATGATGC AGCCAAGCCT 
GAAGACGTGT ATAAATTTGA AGATCTTCTT TCCCCTGCGG AGTATGAAGC TCTTCAGAGC 
CCATCTGAAG CTTTCAGGAA CGTCACGTCA GAAGAAATAC TGAAGATGAT TGAGGAGAAC 
AGCCATTGCA CCTTTGTCAT AGAAGCGTTG AAGTCTTTGC CATCAGATGT GGAGAGCCGA 
GACCGCCAGG CCCGATGCAT ATGGTTTCTG GATACCCTCA TCAAATTTCG AGCTCATAGG 
GTAGTTAAGC GGAAAAGTGC TCTGGGACCT GGAGTTCCCC ACATCATCAA CACCAAACTG 
CTGAAGCACT TTACTTGCTT GACCTACAAC AATGGCAGAT TACGGAACTT AATTTCGGAT 
TCTATGAAGG CGAAGATTAC TGCATATGTG ATCATACTTG CCTTGCACAT ACATGACTTC 
CAAATTGACC TGACAGTGTT ACAGAGGGAC TTGAAGCTCA GTGAGAAAAG GATGATGGAG 
ATAGCCAAAG CCATGAGGCT GAAGATCTCC AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT 
GAAGAAGATC ACAAACTGGG CACCCTGTCC CTCCCGCTGC CTCCAGCCCA GACCTCAGAC 
CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269695.1
CDS	418..1467
Translation	MMLNCSTCSHYFQVFHQESKIIFWKEPRTCFLILSLPLPGELTWDVSVESELALESQTKTYREKMDSCIEAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAETIIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENSHCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGPGVPHIINTKLLKHFTCLTYNNGRLRNLISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGSEEDHKLGTLSLPLPPAQTSDRLAKRRKIT

Target ORF information:

RefSeq Version	NM_001282766.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282766.1

ORF Insert Sequence:

ATGATGCTGA ATTGTTCAAC ATGCAGCCAC TATTTTCAGG TCTTTCACCA AGAAAGCAAA 
ATTATTTTCT GGAAAGAGCC AAGGACTTGT TTTCTAATCC TGTCTCTGCC ACTACCTGGT 
GAACTGACCT GGGATGTATC AGTTGAGAGT GAACTGGCGC TAGAGAGTCA GACCAAAACT 
TACAGAGAAA AGATGGATTC TTGTATTGAA GCCTTTGGTA CCACCAAACA GAAGCGAGCT 
CTGAACACCA GGAGAATGAA CAGAGTTGGC AATGAATCTT TGAATCGTGC AGTGGCTAAA 
GCTGCAGAGA CTATCATTGA TACGAAGGGT GTGACTGCTC TGGTCAGCGA TGCTATCCAC 
AATGACTTGC AAGATGACTC CCTCTACCTT CCTCCCTGCT ATGATGATGC AGCCAAGCCT 
GAAGACGTGT ATAAATTTGA AGATCTTCTT TCCCCTGCGG AGTATGAAGC TCTTCAGAGC 
CCATCTGAAG CTTTCAGGAA CGTCACGTCA GAAGAAATAC TGAAGATGAT TGAGGAGAAC 
AGCCATTGCA CCTTTGTCAT AGAAGCGTTG AAGTCTTTGC CATCAGATGT GGAGAGCCGA 
GACCGCCAGG CCCGATGCAT ATGGTTTCTG GATACCCTCA TCAAATTTCG AGCTCATAGG 
GTAGTTAAGC GGAAAAGTGC TCTGGGACCT GGAGTTCCCC ACATCATCAA CACCAAACTG 
CTGAAGCACT TTACTTGCTT GACCTACAAC AATGGCAGAT TACGGAACTT AATTTCGGAT 
TCTATGAAGG CGAAGATTAC TGCATATGTG ATCATACTTG CCTTGCACAT ACATGACTTC 
CAAATTGACC TGACAGTGTT ACAGAGGGAC TTGAAGCTCA GTGAGAAAAG GATGATGGAG 
ATAGCCAAAG CCATGAGGCT GAAGATCTCC AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT 
GAAGAAGATC ACAAACTGGG CACCCTGTCC CTCCCGCTGC CTCCAGCCCA GACCTCAGAC 
CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POLR1E ( XM_005251547.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005251604.1 Homo sapiens polymerase (RNA) I subunit E (POLR1E), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu42823
Clone ID Related Accession (Same CDS sequence)	XM_005251547.2
Accession Version	XM_005251547.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1446bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	DNA-directed RNA polymerase I subunit RPA49 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005251547.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACCAGG CCTCTGCTGT CAGCCTCCTT CCGCGAGACA TTCCCTCCTG TCACAGCCCC 
TCCCCAGGGT TCTCCCACCT CCCTACCTCC TCTTCTCAGC TGGCCCCGGA TCTCCTCCAG 
TTCCCTTTGG GTCAGGACCC GAGCTTCCTT GCCATCCCCA TTCTGACACT CCCTCCCAGT 
GACAGTCTAG TCCCACCGTA CATTGTGTGG TACATTGTGT GGCCTTCTGC TCTCATCTCA 
TTCTTGGGCT GCACTCTTAC AGTCCAGTTC TCCAACGGGA AGCTACAGAG TCCAGGCAAC 
ATGCGCTTTA CCTTGTATGA GAACAAAGAT TCCACCAACC CCAGGAAGAG GAATCAACGG 
ATCCTGGCAG CTGAAACAGA TAGGCTCTCC TATGTGGGAA ACAATTTTGG GACTGGAGCC 
CTCAAATGCA ACACTTTGTG CAGGCACTTT GTGGGAATTT TGAACAAGAC CTCTGGCCAA 
ATGGAAGTAT ATGATGCTGA ATTGTTCAAC ATGCAGCCAC TATTTTCAGA TGTATCAGTT 
GAGAGTGAAC TGGCGCTAGA GAGTCAGACC AAAACTTACA GAGAAAAGAT GGATTCTTGT 
ATTGAAGCCT TTGGTACCAC CAAACAGAAG CGAGCTCTGA ACACCAGGAG AATGAACAGA 
GTTGGCAATG AATCTTTGAA TCGTGCAGTG GCTAAAGCTG CAGAGACTAT CATTGATACG 
AAGGGTGTGA CTGCTCTGGT CAGCGATGCT ATCCACAATG ACTTGCAAGA TGACTCCCTC 
TACCTTCCTC CCTGCTATGA TGATGCAGCC AAGCCTGAAG ACGTGTATAA ATTTGAAGAT 
CTTCTTTCCC CTGCGGAGTA TGAAGCTCTT CAGAGCCCAT CTGAAGCTTT CAGGAACGTC 
ACGTCAGAAG AAATACTGAA GATGATTGAG GAGAACAGCC ATTGCACCTT TGTCATAGAA 
GCGTTGAAGT CTTTGCCATC AGATGTGGAG AGCCGAGACC GCCAGGCCCG ATGCATATGG 
TTTCTGGATA CCCTCATCAA ATTTCGAGCT CATAGGGTAG TTAAGCGGAA AAGTGCTCTG 
GGACCTGGAG TTCCCCACAT CATCAACACC AAACTGCTGA AGCACTTTAC TTGCTTGACC 
TACAACAATG GCAGATTACG GAACTTAATT TCGGATTCTA TGAAGGCGAA GATTACTGCA 
TATGTGATCA TACTTGCCTT GCACATACAT GACTTCCAAA TTGACCTGAC AGTGTTACAG 
AGGGACTTGA AGCTCAGTGA GAAAAGGATG ATGGAGATAG CCAAAGCCAT GAGGCTGAAG 
ATCTCCAAAA GAAGGGTGTC TGTGGCCGCC GGCAGTGAAG AAGATCACAA GCTGGGCACC 
CTGTCCCTCC CGCTGCCTCC AGCCCAGACC TCAGACCGCC TGGCAAAGCG GAGGAAGATT 
ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005251604.1
CDS	173..1618
Translation	MYQASAVSLLPRDIPSCHSPSPGFSHLPTSSSQLAPDLLQFPLGQDPSFLAIPILTLPPSDSLVPPYIVWYIVWPSALISFLGCTLTVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFSDVSVESELALESQTKTYREKMDSCIEAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAETIIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENSHCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGPGVPHIINTKLLKHFTCLTYNNGRLRNLISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGSEEDHKLGTLSLPLPPAQTSDRLAKRRKIT

Target ORF information:

RefSeq Version	XM_005251547.2
Organism	Homo sapiens(human)
Definition	Homo sapiens polymerase (RNA) I subunit E (POLR1E), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005251547.2

ORF Insert Sequence:

ATGTACCAGG CCTCTGCTGT CAGCCTCCTT CCGCGAGACA TTCCCTCCTG TCACAGCCCC 
TCCCCAGGGT TCTCCCACCT CCCTACCTCC TCTTCTCAGC TGGCCCCGGA TCTCCTCCAG 
TTCCCTTTGG GTCAGGACCC GAGCTTCCTT GCCATCCCCA TTCTGACACT CCCTCCCAGT 
GACAGTCTAG TCCCACCGTA CATTGTGTGG TACATTGTGT GGCCTTCTGC TCTCATCTCA 
TTCTTGGGCT GCACTCTTAC AGTCCAGTTC TCCAACGGGA AGCTACAGAG TCCAGGCAAC 
ATGCGCTTTA CCTTGTATGA GAACAAAGAT TCCACCAACC CCAGGAAGAG GAATCAACGG 
ATCCTGGCAG CTGAAACAGA TAGGCTCTCC TATGTGGGAA ACAATTTTGG GACTGGAGCC 
CTCAAATGCA ACACTTTGTG CAGGCACTTT GTGGGAATTT TGAACAAGAC CTCTGGCCAA 
ATGGAAGTAT ATGATGCTGA ATTGTTCAAC ATGCAGCCAC TATTTTCAGA TGTATCAGTT 
GAGAGTGAAC TGGCGCTAGA GAGTCAGACC AAAACTTACA GAGAAAAGAT GGATTCTTGT 
ATTGAAGCCT TTGGTACCAC CAAACAGAAG CGAGCTCTGA ACACCAGGAG AATGAACAGA 
GTTGGCAATG AATCTTTGAA TCGTGCAGTG GCTAAAGCTG CAGAGACTAT CATTGATACG 
AAGGGTGTGA CTGCTCTGGT CAGCGATGCT ATCCACAATG ACTTGCAAGA TGACTCCCTC 
TACCTTCCTC CCTGCTATGA TGATGCAGCC AAGCCTGAAG ACGTGTATAA ATTTGAAGAT 
CTTCTTTCCC CTGCGGAGTA TGAAGCTCTT CAGAGCCCAT CTGAAGCTTT CAGGAACGTC 
ACGTCAGAAG AAATACTGAA GATGATTGAG GAGAACAGCC ATTGCACCTT TGTCATAGAA 
GCGTTGAAGT CTTTGCCATC AGATGTGGAG AGCCGAGACC GCCAGGCCCG ATGCATATGG 
TTTCTGGATA CCCTCATCAA ATTTCGAGCT CATAGGGTAG TTAAGCGGAA AAGTGCTCTG 
GGACCTGGAG TTCCCCACAT CATCAACACC AAACTGCTGA AGCACTTTAC TTGCTTGACC 
TACAACAATG GCAGATTACG GAACTTAATT TCGGATTCTA TGAAGGCGAA GATTACTGCA 
TATGTGATCA TACTTGCCTT GCACATACAT GACTTCCAAA TTGACCTGAC AGTGTTACAG 
AGGGACTTGA AGCTCAGTGA GAAAAGGATG ATGGAGATAG CCAAAGCCAT GAGGCTGAAG 
ATCTCCAAAA GAAGGGTGTC TGTGGCCGCC GGCAGTGAAG AAGATCACAA GCTGGGCACC 
CTGTCCCTCC CGCTGCCTCC AGCCCAGACC TCAGACCGCC TGGCAAAGCG GAGGAAGATT 
ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POLR1E ( NM_022490.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071935.1 Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.

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CloneID	OHu11924
Clone ID Related Accession (Same CDS sequence)	NM_022490.3 , NM_022490.2
Accession Version	NM_022490.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556640000000
Organism	Homo sapiens(human)
Product	DNA-directed RNA polymerase I subunit RPA49 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7, AK024032.1 and BC001337.1. On Nov 22, 2018 this sequence version replaced NM_022490.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1142558.1, SRR1803612.273198.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC 
CAGAGAGCTG TACTGGTCCA GTTCTCCAAC GGGAAGCTAC AGAGTCCAGG CAACATGCGC 
TTTACCTTGT ATGAGAACAA AGATTCCACC AACCCCAGGA AGAGGAATCA ACGGATCCTG 
GCAGCTGAAA CAGATAGGCT CTCCTATGTG GGAAACAATT TTGGGACTGG AGCCCTCAAA 
TGCAACACTT TGTGCAGGCA CTTTGTGGGA ATTTTGAACA AGACCTCTGG CCAAATGGAA 
GTATATGATG CTGAATTGTT CAACATGCAG CCACTATTTT CAGATGTATC AGTTGAGAGT 
GAACTGGCGC TAGAGAGTCA GACCAAAACT TACAGAGAAA AGATGGATTC TTGTATTGAA 
GCCTTTGGTA CCACCAAACA GAAGCGAGCT CTGAACACCA GGAGAATGAA CAGAGTTGGC 
AATGAATCTT TGAATCGTGC AGTGGCTAAA GCTGCAGAGA CTATCATTGA TACGAAGGGT 
GTGACTGCTC TGGTCAGCGA TGCTATCCAC AATGACTTGC AAGATGACTC CCTCTACCTT 
CCTCCCTGCT ATGATGATGC AGCCAAGCCT GAAGACGTGT ATAAATTTGA AGATCTTCTT 
TCCCCTGCGG AGTATGAAGC TCTTCAGAGC CCATCTGAAG CTTTCAGGAA CGTCACGTCA 
GAAGAAATAC TGAAGATGAT TGAGGAGAAC AGCCATTGCA CCTTTGTCAT AGAAGCGTTG 
AAGTCTTTGC CATCAGATGT GGAGAGCCGA GACCGCCAGG CCCGATGCAT ATGGTTTCTG 
GATACCCTCA TCAAATTTCG AGCTCATAGG GTAGTTAAGC GGAAAAGTGC TCTGGGACCT 
GGAGTTCCCC ACATCATCAA CACCAAACTG CTGAAGCACT TTACTTGCTT GACCTACAAC 
AATGGCAGAT TACGGAACTT AATTTCGGAT TCTATGAAGG CGAAGATTAC TGCATATGTG 
ATCATACTTG CCTTGCACAT ACATGACTTC CAAATTGACC TGACAGTGTT ACAGAGGGAC 
TTGAAGCTCA GTGAGAAAAG GATGATGGAG ATAGCCAAAG CCATGAGGCT GAAGATCTCC 
AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT GAAGAAGATC ACAAACTGGG CACCCTGTCC 
CTCCCGCTGC CTCCAGCCCA GACCTCAGAC CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071935.1
CDS	101..1360
Translation	MAAEVLPSARWQYCGAPDGSQRAVLVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFSDVSVESELALESQTKTYREKMDSCIEAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAETIIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENSHCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGPGVPHIINTKLLKHFTCLTYNNGRLRNLISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGSEEDHKLGTLSLPLPPAQTSDRLAKRRKIT

Target ORF information:

RefSeq Version	NM_022490.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022490.3

ORF Insert Sequence:

ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC 
CAGAGAGCTG TACTGGTCCA GTTCTCCAAC GGGAAGCTAC AGAGTCCAGG CAACATGCGC 
TTTACCTTGT ATGAGAACAA AGATTCCACC AACCCCAGGA AGAGGAATCA ACGGATCCTG 
GCAGCTGAAA CAGATAGGCT CTCCTATGTG GGAAACAATT TTGGGACTGG AGCCCTCAAA 
TGCAACACTT TGTGCAGGCA CTTTGTGGGA ATTTTGAACA AGACCTCTGG CCAAATGGAA 
GTATATGATG CTGAATTGTT CAACATGCAG CCACTATTTT CAGATGTATC AGTTGAGAGT 
GAACTGGCGC TAGAGAGTCA GACCAAAACT TACAGAGAAA AGATGGATTC TTGTATTGAA 
GCCTTTGGTA CCACCAAACA GAAGCGAGCT CTGAACACCA GGAGAATGAA CAGAGTTGGC 
AATGAATCTT TGAATCGTGC AGTGGCTAAA GCTGCAGAGA CTATCATTGA TACGAAGGGT 
GTGACTGCTC TGGTCAGCGA TGCTATCCAC AATGACTTGC AAGATGACTC CCTCTACCTT 
CCTCCCTGCT ATGATGATGC AGCCAAGCCT GAAGACGTGT ATAAATTTGA AGATCTTCTT 
TCCCCTGCGG AGTATGAAGC TCTTCAGAGC CCATCTGAAG CTTTCAGGAA CGTCACGTCA 
GAAGAAATAC TGAAGATGAT TGAGGAGAAC AGCCATTGCA CCTTTGTCAT AGAAGCGTTG 
AAGTCTTTGC CATCAGATGT GGAGAGCCGA GACCGCCAGG CCCGATGCAT ATGGTTTCTG 
GATACCCTCA TCAAATTTCG AGCTCATAGG GTAGTTAAGC GGAAAAGTGC TCTGGGACCT 
GGAGTTCCCC ACATCATCAA CACCAAACTG CTGAAGCACT TTACTTGCTT GACCTACAAC 
AATGGCAGAT TACGGAACTT AATTTCGGAT TCTATGAAGG CGAAGATTAC TGCATATGTG 
ATCATACTTG CCTTGCACAT ACATGACTTC CAAATTGACC TGACAGTGTT ACAGAGGGAC 
TTGAAGCTCA GTGAGAAAAG GATGATGGAG ATAGCCAAAG CCATGAGGCT GAAGATCTCC 
AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT GAAGAAGATC ACAAACTGGG CACCCTGTCC 
CTCCCGCTGC CTCCAGCCCA GACCTCAGAC CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POLR1E ( NM_022490.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_071935.1 Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu11924
Clone ID Related Accession (Same CDS sequence)	NM_022490.3 , NM_022490.2
Accession Version	NM_022490.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	DNA-directed RNA polymerase I subunit RPA49 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7, AK024032.1 and BC001337.1. On Sep 19, 2013 this sequence version replaced NM_022490.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC001337.1, BC014331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC 
CAGAGAGCTG TACTGGTCCA GTTCTCCAAC GGGAAGCTAC AGAGTCCAGG CAACATGCGC 
TTTACCTTGT ATGAGAACAA AGATTCCACC AACCCCAGGA AGAGGAATCA ACGGATCCTG 
GCAGCTGAAA CAGATAGGCT CTCCTATGTG GGAAACAATT TTGGGACTGG AGCCCTCAAA 
TGCAACACTT TGTGCAGGCA CTTTGTGGGA ATTTTGAACA AGACCTCTGG CCAAATGGAA 
GTATATGATG CTGAATTGTT CAACATGCAG CCACTATTTT CAGATGTATC AGTTGAGAGT 
GAACTGGCGC TAGAGAGTCA GACCAAAACT TACAGAGAAA AGATGGATTC TTGTATTGAA 
GCCTTTGGTA CCACCAAACA GAAGCGAGCT CTGAACACCA GGAGAATGAA CAGAGTTGGC 
AATGAATCTT TGAATCGTGC AGTGGCTAAA GCTGCAGAGA CTATCATTGA TACGAAGGGT 
GTGACTGCTC TGGTCAGCGA TGCTATCCAC AATGACTTGC AAGATGACTC CCTCTACCTT 
CCTCCCTGCT ATGATGATGC AGCCAAGCCT GAAGACGTGT ATAAATTTGA AGATCTTCTT 
TCCCCTGCGG AGTATGAAGC TCTTCAGAGC CCATCTGAAG CTTTCAGGAA CGTCACGTCA 
GAAGAAATAC TGAAGATGAT TGAGGAGAAC AGCCATTGCA CCTTTGTCAT AGAAGCGTTG 
AAGTCTTTGC CATCAGATGT GGAGAGCCGA GACCGCCAGG CCCGATGCAT ATGGTTTCTG 
GATACCCTCA TCAAATTTCG AGCTCATAGG GTAGTTAAGC GGAAAAGTGC TCTGGGACCT 
GGAGTTCCCC ACATCATCAA CACCAAACTG CTGAAGCACT TTACTTGCTT GACCTACAAC 
AATGGCAGAT TACGGAACTT AATTTCGGAT TCTATGAAGG CGAAGATTAC TGCATATGTG 
ATCATACTTG CCTTGCACAT ACATGACTTC CAAATTGACC TGACAGTGTT ACAGAGGGAC 
TTGAAGCTCA GTGAGAAAAG GATGATGGAG ATAGCCAAAG CCATGAGGCT GAAGATCTCC 
AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT GAAGAAGATC ACAAACTGGG CACCCTGTCC 
CTCCCGCTGC CTCCAGCCCA GACCTCAGAC CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071935.1
CDS	114..1373
Translation	MAAEVLPSARWQYCGAPDGSQRAVLVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFSDVSVESELALESQTKTYREKMDSCIEAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAETIIDTKGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNVTSEEILKMIEENSHCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSALGPGVPHIINTKLLKHFTCLTYNNGRLRNLISDSMKAKITAYVIILALHIHDFQIDLTVLQRDLKLSEKRMMEIAKAMRLKISKRRVSVAAGSEEDHKLGTLSLPLPPAQTSDRLAKRRKIT

Target ORF information:

RefSeq Version	NM_022490.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA polymerase I subunit E (POLR1E), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022490.2

ORF Insert Sequence:

ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC 
CAGAGAGCTG TACTGGTCCA GTTCTCCAAC GGGAAGCTAC AGAGTCCAGG CAACATGCGC 
TTTACCTTGT ATGAGAACAA AGATTCCACC AACCCCAGGA AGAGGAATCA ACGGATCCTG 
GCAGCTGAAA CAGATAGGCT CTCCTATGTG GGAAACAATT TTGGGACTGG AGCCCTCAAA 
TGCAACACTT TGTGCAGGCA CTTTGTGGGA ATTTTGAACA AGACCTCTGG CCAAATGGAA 
GTATATGATG CTGAATTGTT CAACATGCAG CCACTATTTT CAGATGTATC AGTTGAGAGT 
GAACTGGCGC TAGAGAGTCA GACCAAAACT TACAGAGAAA AGATGGATTC TTGTATTGAA 
GCCTTTGGTA CCACCAAACA GAAGCGAGCT CTGAACACCA GGAGAATGAA CAGAGTTGGC 
AATGAATCTT TGAATCGTGC AGTGGCTAAA GCTGCAGAGA CTATCATTGA TACGAAGGGT 
GTGACTGCTC TGGTCAGCGA TGCTATCCAC AATGACTTGC AAGATGACTC CCTCTACCTT 
CCTCCCTGCT ATGATGATGC AGCCAAGCCT GAAGACGTGT ATAAATTTGA AGATCTTCTT 
TCCCCTGCGG AGTATGAAGC TCTTCAGAGC CCATCTGAAG CTTTCAGGAA CGTCACGTCA 
GAAGAAATAC TGAAGATGAT TGAGGAGAAC AGCCATTGCA CCTTTGTCAT AGAAGCGTTG 
AAGTCTTTGC CATCAGATGT GGAGAGCCGA GACCGCCAGG CCCGATGCAT ATGGTTTCTG 
GATACCCTCA TCAAATTTCG AGCTCATAGG GTAGTTAAGC GGAAAAGTGC TCTGGGACCT 
GGAGTTCCCC ACATCATCAA CACCAAACTG CTGAAGCACT TTACTTGCTT GACCTACAAC 
AATGGCAGAT TACGGAACTT AATTTCGGAT TCTATGAAGG CGAAGATTAC TGCATATGTG 
ATCATACTTG CCTTGCACAT ACATGACTTC CAAATTGACC TGACAGTGTT ACAGAGGGAC 
TTGAAGCTCA GTGAGAAAAG GATGATGGAG ATAGCCAAAG CCATGAGGCT GAAGATCTCC 
AAAAGAAGGG TGTCTGTGGC CGCCGGCAGT GAAGAAGATC ACAAACTGGG CACCCTGTCC 
CTCCCGCTGC CTCCAGCCCA GACCTCAGAC CGCCTGGCAA AGCGGAGGAA GATTACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7.
Molecular cell52(3)303-13(2013 Nov)
Chen S,Seiler J,Santiago-Reichelt M,Felbel K,Grummt I,Voit R

The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription.
EMBO reports7(5)525-30(2006 May)
Percipalle P,Fomproix N,Cavellán E,Voit R,Reimer G,Krüger T,Thyberg J,Scheer U,Grummt I,Farrants AK

Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.
Molecular and cellular biology24(14)6338-49(2004 Jul)
Yamamoto K,Yamamoto M,Hanada K,Nogi Y,Matsuyama T,Muramatsu M

Regulation of ribosomal RNA synthesis during the final phases of porcine oocyte growth.
Biology of reproduction70(4)925-35(2004 Apr)
Bjerregaard B,Wrenzycki C,Philimonenko VV,Hozak P,Laurincik J,Niemann H,Motlik J,Maddox-Hyttel P

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
Nature cell biology6(2)97-105(2004 Feb)
Bouwmeester T,Bauch A,Ruffner H,Angrand PO,Bergamini G,Croughton K,Cruciat C,Eberhard D,Gagneur J,Ghidelli S,Hopf C,Huhse B,Mangano R,Michon AM,Schirle M,Schlegl J,Schwab M,Stein MA,Bauer A,Casari G,Drewes G,Gavin AC,Jackson DB,Joberty G,Neubauer G,Rick J,Kuster B,Superti-Furga G

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POLR1E cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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