DMRTB1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DMRTB1
Entrez Gene ID	63948
Full Name	DMRT like family B with proline rich C-terminal 1
General protein information	Preferred Names DMRT like family B with proline rich C-terminal 1 Names doublesex- and mab-3-related transcription factor B1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p32.3
Disorder MIM:	614805

mRNA and Protein(s)

mRNA	Protein	Name
NM_033067.2	NP_149056.1	doublesex- and mab-3-related transcription factor B1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	DMRTB1	XP_005620332.1
Macaca mulatta (Rhesus monkey)	LOC714424	XP_001112973.1
Bos taurus (cattle)	DMRTB1	XP_002686430.2
Homo sapiens (human)	DMRTB1	NP_149056.1
Rattus norvegicus (Norway rat)	Dmrtb1	NP_001178690.1
Pan troglodytes (chimpanzee)	DMRTB1	XP_001148838.1
Mus musculus (house mouse)	Dmrtb1	NP_063925.1

Gene Ontology
Bibliography

Related articles in PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Genome-wide association of lipid-lowering response to statins in combined study populations.
Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, Li X, Wilke RA, Rieder MJ, Williams PT, Ridker PM, Chatterjee A, Rotter JI, Nickerson DA, Stephens M, Krauss RM
PloS one5(3)e9763(2010 Mar)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY
Cell125(4)801-14(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DMRTB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DMRTB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29885	NM_033067.2 Latest version!	Homo sapiens DMRT like family B with proline rich C-terminal 1 (DMRTB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00

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2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DMRTB1 ( NM_033067.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_149056.1 Homo sapiens DMRT like family B with proline rich C-terminal 1 (DMRTB1), mRNA.

Price & Availability↑

CloneID	OHu29885
Clone ID Related Accession (Same CDS sequence)	NM_033067.2
Accession Version	NM_033067.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556812800000
Organism	Homo sapiens(human)
Product	doublesex- and mab-3-related transcription factor B1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK057273.1 and BC029566.1. On Feb 7, 2015 this sequence version replaced NM_033067.1. ##Evidence-Data-START## Transcript exon combination :: AK057273.1, ERR279850.423.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGACA AAATGGTGCG CACCCCCAAG TGCTCGAGAT GCAGGAACCA TGGCTTCCTG 
GTGCCCGTCA AGGGACACGC GGGCAAATGC CGCTGGAAGC AGTGCCTCTG CGAGAAGTGC 
TACCTGATCT CCGAGCGCCA GAAGATCATG GCCGCGCAGA AGGTGCTCAA GACGCAGGCC 
GCCGAGGAGG AGCAGGAGGC GGCCCTGTGT GCGCAGGGGC CCAAGCAGGC CTCCGGGGCT 
GCGGCCGCCG CCCCCGCCCC CGTCCCCGTC CCGGCCGCGA GCCTCCGCCC GCTGTCCCCG 
GGGACTCCCT CCGGAGACGC CGACCCGGGA CCCGAGGGCC GCGCGGCCGC TTGCTTCTTC 
GAGCAGCCCC CGCGGGGCCG GAACCCCGGC CCGAGAGCCC TCCAGCCGGT TCTGGGCGGC 
CGCAGCCACG TGGAGCCGAG CGAGCGAGCC GCCGTGGCGA TGCCCAGCCT TGCGGGACCC 
CCTTTTGGGG CGGAGGCCGC AGGCAGTGGC TACCCTGGCC CCCTAGACCT GCGCAGGCCG 
ATGCGGACCG TGCCCGGCCC ACTGTTCACC GACTTTGTGC GCCCTCTGAA CATCAACCCG 
GACCGTGCAC TGGGCCCTGA GTACCCTGGT GGCTCCAGCA TGCACCCCTA CTGCCCGTTC 
CCGCTGGGCT ACCTGGACGC CCCTCCTGGC GTCCCCCTGC AGCAGGGCTT CCGGCATGTG 
TCCCGCAGCC AGTACCAAGG CGGAGGCTTG GTGTCAGAAC CAGGAGGAGA CTTCCAGCCA 
AGCTACTACC TGCCGCCGCC GCCGCCGCCA CTGCCGCCCC TTCCACCGCT TCCACCGCAG 
CCCCAGTTCC TCCCGCCAGG CTACCTCTCT GCGCTCCACT TCCTCCCCCC GCCACCGCCA 
CCACCACCTC CATCATCTTT CTCACTGACC GTCCTGTTTG ATACTGACAA GGAGAACACT 
GATGACCAGG ATGCAGAGGT ACTGTCGGGT GAGCCCAGCC AGCCATCGTC TCAGGAGCAG 
TCCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149056.1
CDS	56..1084
Translation	MADKMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVLFDTDKENTDDQDAEVLSGEPSQPSSQEQSD

Target ORF information:

RefSeq Version	NM_033067.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DMRT like family B with proline rich C-terminal 1 (DMRTB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033067.2

ORF Insert Sequence:

ATGGCCGACA AAATGGTGCG CACCCCCAAG TGCTCGAGAT GCAGGAACCA TGGCTTCCTG 
GTGCCCGTCA AGGGACACGC GGGCAAATGC CGCTGGAAGC AGTGCCTCTG CGAGAAGTGC 
TACCTGATCT CCGAGCGCCA GAAGATCATG GCCGCGCAGA AGGTGCTCAA GACGCAGGCC 
GCCGAGGAGG AGCAGGAGGC GGCCCTGTGT GCGCAGGGGC CCAAGCAGGC CTCCGGGGCT 
GCGGCCGCCG CCCCCGCCCC CGTCCCCGTC CCGGCCGCGA GCCTCCGCCC GCTGTCCCCG 
GGGACTCCCT CCGGAGACGC CGACCCGGGA CCCGAGGGCC GCGCGGCCGC TTGCTTCTTC 
GAGCAGCCCC CGCGGGGCCG GAACCCCGGC CCGAGAGCCC TCCAGCCGGT TCTGGGCGGC 
CGCAGCCACG TGGAGCCGAG CGAGCGAGCC GCCGTGGCGA TGCCCAGCCT TGCGGGACCC 
CCTTTTGGGG CGGAGGCCGC AGGCAGTGGC TACCCTGGCC CCCTAGACCT GCGCAGGCCG 
ATGCGGACCG TGCCCGGCCC ACTGTTCACC GACTTTGTGC GCCCTCTGAA CATCAACCCG 
GACCGTGCAC TGGGCCCTGA GTACCCTGGT GGCTCCAGCA TGCACCCCTA CTGCCCGTTC 
CCGCTGGGCT ACCTGGACGC CCCTCCTGGC GTCCCCCTGC AGCAGGGCTT CCGGCATGTG 
TCCCGCAGCC AGTACCAAGG CGGAGGCTTG GTGTCAGAAC CAGGAGGAGA CTTCCAGCCA 
AGCTACTACC TGCCGCCGCC GCCGCCGCCA CTGCCGCCCC TTCCACCGCT TCCACCGCAG 
CCCCAGTTCC TCCCGCCAGG CTACCTCTCT GCGCTCCACT TCCTCCCCCC GCCACCGCCA 
CCACCACCTC CATCATCTTT CTCACTGACC GTCCTGTTTG ATACTGACAA GGAGAACACT 
GATGACCAGG ATGCAGAGGT ACTGTCGGGT GAGCCCAGCC AGCCATCGTC TCAGGAGCAG 
TCCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Taşan M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barabási AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Genome-wide association of lipid-lowering response to statins in combined study populations.
PloS one5(3)e9763(2010 Mar)
Barber MJ,Mangravite LM,Hyde CL,Chasman DI,Smith JD,McCarty CA,Li X,Wilke RA,Rieder MJ,Williams PT,Ridker PM,Chatterjee A,Rotter JI,Nickerson DA,Stephens M,Krauss RM

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Cell125(4)801-14(2006 May)
Lim J,Hao T,Shaw C,Patel AJ,Szabó G,Rual JF,Fisk CJ,Li N,Smolyar A,Hill DE,Barabási AL,Vidal M,Zoghbi HY

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DMRTB1 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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