MSMO1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MSMO1
Entrez Gene ID	6307
Full Name	methylsterol monooxygenase 1
Synonyms	DESP4,ERG25,MCCPD,SC4MOL
General protein information	Preferred Names methylsterol monooxygenase 1 Names methylsterol monooxygenase 1 C-4 methylsterol oxidase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q32.3
Summary	Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	607545
Disorder Html:	Microcephaly, congenital cataract, and psoriasiform dermatitis, 616834 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017369.2	NP_001017369.1	methylsterol monooxygenase 1 isoform 2
XM_005263176.1	XP_005263233.1	methylsterol monooxygenase 1 isoform X1
XM_005263176.2	XP_005263233.1	methylsterol monooxygenase 1 isoform X1
NM_006745.4	NP_006736.1	methylsterol monooxygenase 1 isoform 1
NM_006745.5	NP_006736.1	methylsterol monooxygenase 1 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MSMO1	XP_003310610.1
Gallus gallus (chicken)	MSMO1	NP_001006438.1
Danio rerio (zebrafish)	msmo1	NP_998518.1
Homo sapiens (human)	MSMO1	NP_006736.1
Rattus norvegicus (Norway rat)	Msmo1	NP_543162.1
Macaca mulatta (Rhesus monkey)	SC4MOL	XP_001101517.1
Bos taurus (cattle)	MSMO1	NP_001092333.1
Magnaporthe oryzae (rice blast fungus)	MGG_17103	XP_003716576.1
Mus musculus (house mouse)	Sc4mol	NP_079712.1
Xenopus tropicalis (tropical clawed frog)	msmo1	NP_001072809.1

Gene Ontology
Bibliography

Related articles in PubMed

The role of sterol-C4-methyl oxidase in epidermal biology.
He M, Smith LD, Chang R, Li X, Vockley J
Biochimica et biophysica acta1841(3)331-5(2014 Mar)

Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.
Chen G, Bentley A, Adeyemo A, Shriner D, Zhou J, Doumatey A, Huang H, Ramos E, Erdos M, Gerry N, Herbert A, Christman M, Rotimi C
Human molecular genetics21(20)4530-6(2012 Oct)

Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay.
He M, Kratz LE, Michel JJ, Vallejo AN, Ferris L, Kelley RI, Hoover JJ, Jukic D, Gibson KM, Wolfe LA, Ramachandran D, Zwick ME, Vockley J
The Journal of clinical investigation121(3)976-84(2011 Mar)

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
Lu Y, Dollé ME, Imholz S, van 't Slot R, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM
Journal of lipid research49(12)2582-9(2008 Dec)

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY
Cell125(4)801-14(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MSMO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MSMO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16929	NM_001017369.2 Latest version!	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu16957	NM_006745.5 Latest version!	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu16957	XM_005263176.2 Latest version!	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
View Old Accession Versions >>
OHu16957	XM_005263176.1	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu16957	NM_006745.4	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MSMO1 ( NM_001017369.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001017369.1 Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16929
Clone ID Related Accession (Same CDS sequence)	NM_001017369.2
Accession Version	NM_001017369.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564848000000
Organism	Homo sapiens(human)
Product	methylsterol monooxygenase 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX441001.2, AK295432.1, BC010653.1 and BU676028.1. On Sep 6, 2011 this sequence version replaced NM_001017369.1. Transcript Variant: This variant (2) lacks an exon in the 5' region, resulting in translation initiation from a downstream AUG codon, as compared to variant 1. The encoded isoform 2 has a shorter N-terminus, as compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.173705.1, SRR1803616.142274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAAGAT GGTATTTTCT TTTGGCAAGA TGCTTTGGTT GTGCAGTCAT TGAAGATACT 
TGGCACTATT TTCTGCATAG ACTCTTACAC CACAAAAGAA TATACAAGTA TATTCATAAA 
GTTCATCATG AGTTTCAGGC TCCATTTGGA ATGGAAGCTG AATATGCACA TCCTTTGGAG 
ACTCTAATTC TTGGAACTGG ATTTTTCATT GGAATCGTGC TTTTGTGTGA TCATGTAATT 
CTTCTTTGGG CATGGGTGAC CATTCGTTTA TTAGAAACTA TTGATGTCCA TAGTGGTTAT 
GATATTCCTC TCAACCCTTT AAATCTGATC CCTTTCTATG CTGGTTCTCG GCATCATGAT 
TTCCACCACA TGAACTTCAT TGGAAACTAT GCTTCAACAT TTACATGGTG GGATCGAATT 
TTTGGAACAG ACTCTCAGTA TAATGCCTAT AATGAAAAGA GGAAGAAGTT TGAGAAAAAG 
ACTGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017369.1
CDS	238..726
Translation	MPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE

Target ORF information:

RefSeq Version	NM_001017369.2
Organism	Homo sapiens(human)
Definition	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017369.2

ORF Insert Sequence:

ATGCCAAGAT GGTATTTTCT TTTGGCAAGA TGCTTTGGTT GTGCAGTCAT TGAAGATACT 
TGGCACTATT TTCTGCATAG ACTCTTACAC CACAAAAGAA TATACAAGTA TATTCATAAA 
GTTCATCATG AGTTTCAGGC TCCATTTGGA ATGGAAGCTG AATATGCACA TCCTTTGGAG 
ACTCTAATTC TTGGAACTGG ATTTTTCATT GGAATCGTGC TTTTGTGTGA TCATGTAATT 
CTTCTTTGGG CATGGGTGAC CATTCGTTTA TTAGAAACTA TTGATGTCCA TAGTGGTTAT 
GATATTCCTC TCAACCCTTT AAATCTGATC CCTTTCTATG CTGGTTCTCG GCATCATGAT 
TTCCACCACA TGAACTTCAT TGGAAACTAT GCTTCAACAT TTACATGGTG GGATCGAATT 
TTTGGAACAG ACTCTCAGTA TAATGCCTAT AATGAAAAGA GGAAGAAGTT TGAGAAAAAG 
ACTGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MSMO1 ( NM_006745.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006736.1 Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16957
Clone ID Related Accession (Same CDS sequence)	XM_005263176.1 , XM_005263176.2 , NM_006745.4 , NM_006745.5
Accession Version	NM_006745.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506873600000
Organism	Homo sapiens(human)
Product	methylsterol monooxygenase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX441001.2, BC010653.1 and BU676028.1. This sequence is a reference standard in the RefSeqGene project. On Sep 6, 2011 this sequence version replaced NM_006745.3. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1660803.234088.1, SRR1803615.219279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006736.1
CDS	131..1012
Translation	MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE

Target ORF information:

RefSeq Version	NM_006745.4
Organism	Homo sapiens(human)
Definition	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006745.4

ORF Insert Sequence:

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MSMO1 ( NM_006745.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006736.1 Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16957
Clone ID Related Accession (Same CDS sequence)	XM_005263176.1 , XM_005263176.2 , NM_006745.4 , NM_006745.5
Accession Version	NM_006745.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577548800000
Organism	Homo sapiens(human)
Product	methylsterol monooxygenase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX441001.2, BC010653.1 and BU676028.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_006745.4. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR3476690.632771.1, SRR1803615.219279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261507.11/ ENSP00000261507.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006736.1
CDS	128..1009
Translation	MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE

Target ORF information:

RefSeq Version	NM_006745.5
Organism	Homo sapiens(human)
Definition	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006745.5

ORF Insert Sequence:

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MSMO1 ( XM_005263176.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005263233.1 Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu16957
Clone ID Related Accession (Same CDS sequence)	XM_005263176.1 , XM_005263176.2 , NM_006745.4 , NM_006745.5
Accession Version	XM_005263176.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	methylsterol monooxygenase 1 isoform X1
Comment

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005263233.1
Translation	MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE

Target ORF information:

RefSeq Version	XM_005263176.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005263176.1

ORF Insert Sequence:

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MSMO1 ( XM_005263176.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005263233.1 Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu16957
Clone ID Related Accession (Same CDS sequence)	XM_005263176.1 , XM_005263176.2 , NM_006745.4 , NM_006745.5
Accession Version	XM_005263176.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	methylsterol monooxygenase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005263176.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005263233.1
CDS	248..1129
Translation	MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE

Target ORF information:

RefSeq Version	XM_005263176.2
Organism	Homo sapiens(human)
Definition	Homo sapiens methylsterol monooxygenase 1 (MSMO1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005263176.2

ORF Insert Sequence:

ATGGCAACAA ATGAAAGTGT CAGCATCTTT AGTTCAGCAT CCTTGGCTGT GGAATATGTA 
GATTCACTTT TACCTGAGAA TCCTCTGCAA GAACCATTTA AAAATGCTTG GAACTATATG 
TTGAATAATT ATACAAAGTT CCAGATTGCA ACATGGGGAT CCCTTATAGT TCATGAAGCC 
CTTTATTTCT TATTCTGTTT ACCTGGATTT TTATTTCAAT TTATACCTTA TATGAAAAAA 
TACAAAATTC AAAAGGATAA GCCAGAGACA TGGGAAAACC AATGGAAGTG TTTCAAAGTT 
CTTCTCTTTA ATCACTTCTG TATCCAGCTG CCTTTGATTT GTGGAACCTA TTATTTTACA 
GAGTATTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTATTT TCTTTTGGCA 
AGATGCTTTG GTTGTGCAGT CATTGAAGAT ACTTGGCACT ATTTTCTGCA TAGACTCTTA 
CACCACAAAA GAATATACAA GTATATTCAT AAAGTTCATC ATGAGTTTCA GGCTCCATTT 
GGAATGGAAG CTGAATATGC ACATCCTTTG GAGACTCTAA TTCTTGGAAC TGGATTTTTC 
ATTGGAATCG TGCTTTTGTG TGATCATGTA ATTCTTCTTT GGGCATGGGT GACCATTCGT 
TTATTAGAAA CTATTGATGT CCATAGTGGT TATGATATTC CTCTCAACCC TTTAAATCTG 
ATCCCTTTCT ATGCTGGTTC TCGGCATCAT GATTTCCACC ACATGAACTT CATTGGAAAC 
TATGCTTCAA CATTTACATG GTGGGATCGA ATTTTTGGAA CAGACTCTCA GTATAATGCC 
TATAATGAAA AGAGGAAGAA GTTTGAGAAA AAGACTGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of sterol-C4-methyl oxidase in epidermal biology.
Biochimica et biophysica acta1841(3)331-5(2014 Mar)
He M,Smith LD,Chang R,Li X,Vockley J

Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.
Human molecular genetics21(20)4530-6(2012 Oct)
Chen G,Bentley A,Adeyemo A,Shriner D,Zhou J,Doumatey A,Huang H,Ramos E,Erdos M,Gerry N,Herbert A,Christman M,Rotimi C

Mutations in the human SC4MOL gene encoding a methyl sterol oxidase cause psoriasiform dermatitis, microcephaly, and developmental delay.
The Journal of clinical investigation121(3)976-84(2011 Mar)
He M,Kratz LE,Michel JJ,Vallejo AN,Ferris L,Kelley RI,Hoover JJ,Jukic D,Gibson KM,Wolfe LA,Ramachandran D,Zwick ME,Vockley J

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
Journal of lipid research49(12)2582-9(2008 Dec)
Lu Y,Dollé ME,Imholz S,van 't Slot R,Verschuren WM,Wijmenga C,Feskens EJ,Boer JM

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Cell125(4)801-14(2006 May)
Lim J,Hao T,Shaw C,Patel AJ,Szabó G,Rual JF,Fisk CJ,Li N,Smolyar A,Hill DE,Barabási AL,Vidal M,Zoghbi HY

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

MSMO1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM