MBOAT4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MBOAT4
Entrez Gene ID	619373
Full Name	membrane bound O-acyltransferase domain containing 4
Synonyms	FKSG89,GOAT,OACT4
General protein information	Preferred Names membrane bound O-acyltransferase domain containing 4 Names ghrelin O-acyltransferase O-acyltransferase (membrane bound) domain containing 4 O-acyltransferase domain-containing protein 4 membrane-bound O-acyltransferase domain-containing protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p12
Disorder MIM:	611940

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100916.2	NP_001094386.1	ghrelin O-acyltransferase
XM_011544609.1	XP_011542911.1	ghrelin O-acyltransferase isoform X1
NM_001100916.1	NP_001094386.1	ghrelin O-acyltransferase
XM_017013726.1	XP_016869215.1	ghrelin O-acyltransferase isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Mboat4	NP_001119786.1
Homo sapiens (human)	MBOAT4	NP_001094386.1
Pan troglodytes (chimpanzee)	MBOAT4	XP_519692.2
Rattus norvegicus (Norway rat)	Mboat4	NP_001100787.2
Gallus gallus (chicken)	MBOAT4	NP_001186218.1
Macaca mulatta (Rhesus monkey)	MBOAT4	XP_002805350.1
Xenopus tropicalis (tropical clawed frog)	LOC100487840	XP_002936505.2
Canis lupus familiaris (dog)	MBOAT4	NP_001188260.1
Bos taurus (cattle)	MBOAT4	NP_001179186.1
Danio rerio (zebrafish)	mboat4	NP_001116416.1

Gene Ontology
Bibliography

Related articles in PubMed

Differential expression of the ghrelin-related mRNAs GHS-R1a, GHS-R1b, and MBOAT4 in Japanese patients with schizophrenia.
Nakata S, Yoshino Y, Okita M, Kawabe K, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Iga JI, Ueno SI
Psychiatry research272334-339(2019 02)

Plasma ghrelin O-acyltransferase (GOAT) enzyme levels: A novel non-invasive diagnosis tool for patients with significant prostate cancer.
Gómez-Gómez E, Jiménez-Vacas JM, Carrasco-Valiente J, Herrero-Aguayo V, Blanca-Pedregosa AM, León-González AJ, Valero-Rosa J, Fernández-Rueda JL, González-Serrano T, López-Miranda J, Gahete MD, Castaño JP, Requena-Tapia MJ, Luque RM
Journal of cellular and molecular medicine22(11)5688-5697(2018 11)

Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Novel Potential Biomarker in Gastroenteropancreatic Neuroendocrine Tumors.
Herrera-Martínez AD, Gahete MD, Sánchez-Sánchez R, Alors-Perez E, Pedraza-Arevalo S, Serrano-Blanch R, Martínez-Fuentes AJ, Gálvez-Moreno MA, Castaño JP, Luque RM
Clinical and translational gastroenterology9(10)196(2018 10)

Identification and Characterization of a New Series of Ghrelin O-Acyl Transferase Inhibitors.
Yoneyama-Hirozane M, Deguchi K, Hirakawa T, Ishii T, Odani T, Matsui J, Nakano Y, Imahashi K, Takakura N, Chisaki I, Takekawa S, Sakamoto J
SLAS discovery : advancing life sciences R & D23(2)154-163(2018 02)

Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.
McGovern-Gooch KR, Mahajani NS, Garagozzo A, Schramm AJ, Hannah LG, Sieburg MA, Chisholm JD, Hougland JL
Biochemistry56(7)919-931(2017 02)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MBOAT4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MBOAT4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31938	NM_001100916.2 Latest version!	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$251.30 $359.00
OHu31938	XM_011544609.1 Latest version!	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$251.30 $359.00
OHu31938	XM_017013726.1 Latest version!	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$251.30 $359.00
View Old Accession Versions >>
OHu31938	NM_001100916.1	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$251.30 $359.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MBOAT4 ( NM_001100916.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001094386.1 Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), mRNA.

Price & Availability↑

CloneID	OHu31938
Clone ID Related Accession (Same CDS sequence)	NM_001100916.2 , XM_011544609.1 , NM_001100916.1 , XM_017013726.1
Accession Version	NM_001100916.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577808000000
Organism	Homo sapiens(human)
Product	ghrelin O-acyltransferase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EU518495.2 and AC026979.9. On May 17, 2019 this sequence version replaced NM_001100916.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU518495.2, DN930415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2146982 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000320542.4/ ENSP00000314196.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094386.1
CDS	65..1372
Translation	MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN

Target ORF information:

RefSeq Version	NM_001100916.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100916.2

ORF Insert Sequence:

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBOAT4 ( NM_001100916.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001094386.1 Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), mRNA.

Price & Availability↑

CloneID	OHu31938
Clone ID Related Accession (Same CDS sequence)	NM_001100916.2 , XM_011544609.1 , NM_001100916.1 , XM_017013726.1
Accession Version	NM_001100916.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529683200000
Organism	Homo sapiens(human)
Product	ghrelin O-acyltransferase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EU518495.2 and AC026979.9. On or before Jun 11, 2008 this sequence version replaced XM_001717299.1, XM_001125855.2, XM_940502.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU518495.2, DN930415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2146982 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094386.1
CDS	84..1391
Translation	MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN

Target ORF information:

RefSeq Version	NM_001100916.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100916.1

ORF Insert Sequence:

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBOAT4 ( XM_011544609.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011542911.1 Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu31938
Clone ID Related Accession (Same CDS sequence)	NM_001100916.2 , XM_011544609.1 , NM_001100916.1 , XM_017013726.1
Accession Version	XM_011544609.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	ghrelin O-acyltransferase isoform X1
Comment

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011542911.1

Translation

MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN

Target ORF information:

RefSeq Version	XM_011544609.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544609.1

ORF Insert Sequence:

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBOAT4 ( XM_017013726.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869215.1 Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), transcript variant X1, mRNA.

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CloneID	OHu31938
Clone ID Related Accession (Same CDS sequence)	NM_001100916.2 , XM_011544609.1 , NM_001100916.1 , XM_017013726.1
Accession Version	XM_017013726.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	ghrelin O-acyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869215.1
CDS	687..1994
Translation	MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN

Target ORF information:

RefSeq Version	XM_017013726.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound O-acyltransferase domain containing 4 (MBOAT4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013726.1

ORF Insert Sequence:

ATGGAGTGGC TTTGGCTGTT CTTTCTCCAT CCTATATCGT TTTACCAGGG GGCTGCATTT 
CCCTTTGCAC TTCTCTTCAA TTATCTCTGC ATCATGGATT CATTCTCCAC TCGTGCCAGG 
TACCTCTTTC TCCTGACTGG AGGAGGTGCC CTGGCCGTGG CTGCCATGGG TTCCTACGCC 
GTGCTCGTCT TCACCCCTGC TGTCTGCGCT GTGGCTCTCC TCTGTTCCCT GGCTCCTCAG 
CAAGTCCACA GGTGGACCTT CTGCTTTCAG ATGAGCTGGC AGACCTTGTG TCACCTAGGT 
CTGCACTACA CTGAGTATTA TCTGCATGAG CCTCCTTCTG TGAGGTTCTG CATCACTCTT 
TCTTCTCTCA TGCTCTTGAC CCAGAGGGTC ACGTCCCTCT CTCTGGACAT TTGTGAGGGG 
AAAGTGAAGG CAGCATCTGG AGGCTTCAGG AGCAGGAGCT CTTTGTCTGA GCATGTGTGT 
AAGGCACTGC CCTATTTCAG CTACTTGCTC TTTTTCCCTG CTCTCCTGGG AGGCTCTCTG 
TGCTCCTTCC AGCGATTTCA GGCTCGTGTT CAAGGGTCCA GTGCTTTGCA TCCCAGACAC 
TCTTTCTGGG CTCTGAGCTG GAGGGGTCTG CAGATTCTTG GACTAGAATG CCTAAACGTG 
GCAGTGAGCA GGGTGGTGGA TGCAGGAGCG GGACTGACTG ATTGCCAGCA ATTCGAGTGC 
ATCTATGTCG TGTGGACCAC AGCTGGGCTT TTCAAGCTCA CCTACTACTC CCACTGGATC 
CTGGACGACT CCCTCCTCCA CGCAGCGGGC TTTGGGCCTG AGCTTGGTCA GAGCCCTGGA 
GAGGAGGGAT ATGTCCCCGA TGCAGACATC TGGACCCTGG AAAGAACCCA CAGGATATCT 
GTGTTCTCAA GAAAGTGGAA CCAAAGCACA GCTCGATGGC TCCGACGGCT TGTATTCCAG 
CACAGCAGGG CTTGGCCGTT GTTGCAGACA TTTGCCTTCT CTGCCTGGTG GCATGGACTC 
CATCCAGGAC AGGTGTTTGG TTTCGTTTGC TGGGCCGTGA TGGTGGAAGC TGACTACCTG 
ATTCACTCCT TTGCCAATGA GTTTATCAGA TCCTGGCCGA TGAGGCTGTT CTATAGAACC 
CTCACCTGGG CCCACACCCA GTTGATCATT GCCTACATCA TGCTGGCTGT GGAGGTCAGG 
AGTCTCTCCT CTCTCTGGTT GCTCTGTAAT TCGTACAACA GTGTCTTTCC CATGGTGTAC 
TGTATTCTGC TTTTGCTATT GGCGAAGAGA AAGCACAAAT GTAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Differential expression of the ghrelin-related mRNAs GHS-R1a, GHS-R1b, and MBOAT4 in Japanese patients with schizophrenia.
Psychiatry research272334-339(2019 02)
Nakata S,Yoshino Y,Okita M,Kawabe K,Yamazaki K,Ozaki Y,Mori Y,Ochi S,Iga JI,Ueno SI

Plasma ghrelin O-acyltransferase (GOAT) enzyme levels: A novel non-invasive diagnosis tool for patients with significant prostate cancer.
Journal of cellular and molecular medicine22(11)5688-5697(2018 11)
Gómez-Gómez E,Jiménez-Vacas JM,Carrasco-Valiente J,Herrero-Aguayo V,Blanca-Pedregosa AM,León-González AJ,Valero-Rosa J,Fernández-Rueda JL,González-Serrano T,López-Miranda J,Gahete MD,Castaño JP,Requena-Tapia MJ,Luque RM

Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Novel Potential Biomarker in Gastroenteropancreatic Neuroendocrine Tumors.
Clinical and translational gastroenterology9(10)196(2018 10)
Herrera-Martínez AD,Gahete MD,Sánchez-Sánchez R,Alors-Perez E,Pedraza-Arevalo S,Serrano-Blanch R,Martínez-Fuentes AJ,Gálvez-Moreno MA,Castaño JP,Luque RM

Identification and Characterization of a New Series of Ghrelin O-Acyl Transferase Inhibitors.
SLAS discovery : advancing life sciences R & D23(2)154-163(2018 02)
Yoneyama-Hirozane M,Deguchi K,Hirakawa T,Ishii T,Odani T,Matsui J,Nakano Y,Imahashi K,Takakura N,Chisaki I,Takekawa S,Sakamoto J

Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.
Biochemistry56(7)919-931(2017 02)
McGovern-Gooch KR,Mahajani NS,Garagozzo A,Schramm AJ,Hannah LG,Sieburg MA,Chisholm JD,Hougland JL

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MBOAT4 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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