RDH5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RDH5
Entrez Gene ID	5959
Full Name	retinol dehydrogenase 5
Synonyms	9cRDH,HSD17B9,RDH1,SDR9C5
General protein information	Preferred Names retinol dehydrogenase 5 Names 11-cis retinol dehydrogenase 11-cis RDH 11-cis RoDH 9-cis retinol dehydrogenase 9-cis-retinol specific dehydrogenase retinol dehydrogenase 1 retinol dehydrogenase 5 (11-cis and 9-cis) retinol dehydrogenase 5 (11-cis/9-cis) short chain dehydrogenase/reductase family 9C member 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.2
Summary	This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010].
Disorder MIM:	601617
Disorder Html:	Fundus albipunctatus, 136880 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001199771.1	NP_001186700.1	11-cis retinol dehydrogenase precursor
NM_002905.4	NP_002896.2	retinol dehydrogenase 5 precursor
NM_002905.3	NP_002896.2	11-cis retinol dehydrogenase precursor
NM_002905.5	NP_002896.2	retinol dehydrogenase 5 precursor
NM_001199771.2	NP_001186700.1	retinol dehydrogenase 5 precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	rdh5	NP_001011363.1
Homo sapiens (human)	RDH5	NP_001186700.1
Mus musculus (house mouse)	Rdh5	NP_598767.1
Rattus norvegicus (Norway rat)	Rdh5	XP_006240872.1
Macaca mulatta (Rhesus monkey)	RDH5	XP_001110917.1
Danio rerio (zebrafish)	rdh5	NP_001025272.1
Bos taurus (cattle)	RDH5	NP_776591.2
Pan troglodytes (chimpanzee)	RDH5	XP_522429.1
Canis lupus familiaris (dog)	RDH5	XP_005625516.1
Gallus gallus (chicken)	RDH5	NP_990044.1

Gene Ontology
Bibliography

Related articles in PubMed

A novel mutation in RDH5 gene causes retinitis pigmentosa in consanguineous Pakistani family.
Sultan N, Ali I, Bukhari SA, Baig SM, Asif M, Qasim M, Naseer MI, Rasool M
Genes & genomics40(5)553-559(2018 05)

Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium.
Wen B, Li S, Li H, Chen Y, Ma X, Wang J, Lu F, Qu J, Hou L
Scientific reports621208(2016 Feb)

RDH5 retinopathy (fundus albipunctatus) with preserved rod function.
Liu X, Liu L, Li H, Xu F, Jiang R, Sui R
Retina (Philadelphia, Pa.)35(3)582-9(2015 Mar)

Cone abnormalities in fundus albipunctatus associated with RDH5 mutations assessed using adaptive optics scanning laser ophthalmoscopy.
Makiyama Y, Ooto S, Hangai M, Ogino K, Gotoh N, Oishi A, Yoshimura N
American journal of ophthalmology157(3)558-70.e1-4(2014 Mar)

A high association with cone dystrophy in Fundus albipunctatus caused by mutations of the RDH5 gene.
Nakamura M, Hotta Y, Tanikawa A, Terasaki H, Miyake Y
Investigative ophthalmology & visual science41(12)3925-32(2000 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RDH5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RDH5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17644	NM_001199771.2 Latest version!	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu17644	NM_002905.5 Latest version!	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
View Old Accession Versions >>
OHu17644	NM_002905.3	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu17644	NM_002905.4	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu17644	NM_001199771.1	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RDH5 ( NM_001199771.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186700.1 Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17644
Clone ID Related Accession (Same CDS sequence)	NM_001199771.1 , NM_002905.4 , NM_002905.3 , NM_002905.5 , NM_001199771.2
Accession Version	NM_001199771.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Homo sapiens(human)
Product	11-cis retinol dehydrogenase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP381700.1, BI765016.1, BC028298.1 and BU617433.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC028298.1, BI765016.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186700.1
CDS	189..1145
Translation	MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY

Target ORF information:

RefSeq Version	NM_001199771.1
Organism	Homo sapiens(human)
Definition	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199771.1

ORF Insert Sequence:

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDH5 ( NM_002905.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002896.2 Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17644
Clone ID Related Accession (Same CDS sequence)	NM_001199771.1 , NM_002905.4 , NM_002905.3 , NM_002905.5 , NM_001199771.2
Accession Version	NM_002905.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559318400000
Organism	Homo sapiens(human)
Product	retinol dehydrogenase 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP381700.1, U43559.1 and BU617433.1. On Jun 2, 2019 this sequence version replaced NM_002905.3. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U43559.1, U89717.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002896.2
CDS	158..1114
Translation	MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY

Target ORF information:

RefSeq Version	NM_002905.4
Organism	Homo sapiens(human)
Definition	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002905.4

ORF Insert Sequence:

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDH5 ( NM_002905.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002896.2 Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17644
Clone ID Related Accession (Same CDS sequence)	NM_001199771.1 , NM_002905.4 , NM_002905.3 , NM_002905.5 , NM_001199771.2
Accession Version	NM_002905.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550332800000
Organism	Homo sapiens(human)
Product	11-cis retinol dehydrogenase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP381700.1, U43559.1 and BU617433.1. This sequence is a reference standard in the RefSeqGene project. On Sep 4, 2008 this sequence version replaced NM_002905.2. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U89717.1, U43559.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002896.2
CDS	184..1140
Translation	MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY

Target ORF information:

RefSeq Version	NM_002905.3
Organism	Homo sapiens(human)
Definition	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002905.3

ORF Insert Sequence:

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDH5 ( NM_002905.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002896.2 Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17644
Clone ID Related Accession (Same CDS sequence)	NM_001199771.1 , NM_002905.4 , NM_002905.3 , NM_002905.5 , NM_001199771.2
Accession Version	NM_002905.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Homo sapiens(human)
Product	retinol dehydrogenase 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP381700.1, U43559.1 and BU617433.1. On Nov 30, 2019 this sequence version replaced NM_002905.4. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U89717.1, U43559.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002896.2
CDS	158..1114
Translation	MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY

Target ORF information:

RefSeq Version	NM_002905.5
Organism	Homo sapiens(human)
Definition	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002905.5

ORF Insert Sequence:

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDH5 ( NM_001199771.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186700.1 Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17644
Clone ID Related Accession (Same CDS sequence)	NM_001199771.1 , NM_002905.4 , NM_002905.3 , NM_002905.5 , NM_001199771.2
Accession Version	NM_001199771.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Homo sapiens(human)
Product	retinol dehydrogenase 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP381700.1, BI765016.1, BC028298.1 and BU617433.1. On Jun 2, 2019 this sequence version replaced NM_001199771.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.69481.1, BC028298.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186700.1
CDS	163..1119
Translation	MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY

Target ORF information:

RefSeq Version	NM_001199771.2
Organism	Homo sapiens(human)
Definition	Homo sapiens retinol dehydrogenase 5 (RDH5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199771.2

ORF Insert Sequence:

ATGTGGCTGC CTCTTCTGCT GGGTGCCTTA CTCTGGGCAG TGCTGTGGTT GCTCAGGGAC 
CGGCAGAGCC TGCCCGCCAG CAATGCCTTT GTCTTCATCA CCGGCTGTGA CTCAGGCTTT 
GGGCGCCTTC TGGCACTGCA GCTGGACCAG AGAGGCTTCC GAGTCCTGGC CAGCTGCCTG 
ACCCCCTCCG GGGCCGAGGA CCTGCAGCGG GTGGCCTCCT CCCGCCTCCA CACCACCCTG 
TTGGATATCA CTGATCCCCA GAGCGTCCAG CAGGCAGCCA AGTGGGTGGA GATGCACGTT 
AAGGAAGCAG GGCTTTTTGG TCTGGTGAAT AATGCTGGTG TGGCTGGTAT CATCGGACCC 
ACACCATGGC TGACCCGGGA CGATTTCCAG CGGGTGCTGA ATGTGAACAC AATGGGTCCC 
ATCGGGGTCA CCCTTGCCCT GCTGCCTCTG CTGCAGCAAG CCCGGGGCCG GGTGATCAAC 
ATCACCAGCG TCCTGGGTCG CCTGGCAGCC AATGGTGGGG GCTACTGTGT CTCCAAATTT 
GGCCTGGAGG CCTTCTCTGA CAGCCTGAGG CGGGATGTAG CTCATTTTGG GATACGAGTC 
TCCATCGTGG AGCCTGGCTT CTTCCGAACC CCTGTGACCA ACCTGGAGAG TCTGGAGAAA 
ACCCTGCAGG CCTGCTGGGC ACGGCTGCCT CCTGCCACAC AGGCCCACTA TGGGGGGGCC 
TTCCTCACCA AGTACCTGAA AATGCAACAG CGCATCATGA ACCTGATCTG TGACCCGGAC 
CTAACCAAGG TGAGCCGATG CCTGGAGCAT GCCCTGACTG CTCGACACCC CCGAACCCGC 
TACAGCCCAG GTTGGGATGC CAAGCTGCTC TGGCTGCCTG CCTCCTACCT GCCAGCCAGC 
CTGGTGGATG CTGTGCTCAC CTGGGTCCTT CCCAAGCCTG CCCAAGCAGT CTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel mutation in RDH5 gene causes retinitis pigmentosa in consanguineous Pakistani family.
Genes & genomics40(5)553-559(2018 05)
Sultan N,Ali I,Bukhari SA,Baig SM,Asif M,Qasim M,Naseer MI,Rasool M

Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium.
Scientific reports621208(2016 Feb)
Wen B,Li S,Li H,Chen Y,Ma X,Wang J,Lu F,Qu J,Hou L

RDH5 retinopathy (fundus albipunctatus) with preserved rod function.
Retina (Philadelphia, Pa.)35(3)582-9(2015 Mar)
Liu X,Liu L,Li H,Xu F,Jiang R,Sui R

Cone abnormalities in fundus albipunctatus associated with RDH5 mutations assessed using adaptive optics scanning laser ophthalmoscopy.
American journal of ophthalmology157(3)558-70.e1-4(2014 Mar)
Makiyama Y,Ooto S,Hangai M,Ogino K,Gotoh N,Oishi A,Yoshimura N

A high association with cone dystrophy in Fundus albipunctatus caused by mutations of the RDH5 gene.
Investigative ophthalmology & visual science41(12)3925-32(2000 Nov)
Nakamura M,Hotta Y,Tanikawa A,Terasaki H,Miyake Y

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

RDH5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM