AVPR1A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AVPR1A
Entrez Gene ID	552
Full Name	arginine vasopressin receptor 1A
Synonyms	AVPR V1a,AVPR1,V1aR
General protein information	Preferred Names arginine vasopressin receptor 1A Names vasopressin V1a receptor SCCL vasopressin subtype 1a receptor V1-vascular vasopressin receptor AVPR1A V1a vasopressin receptor antidiuretic hormone receptor 1A vascular/hepatic-type arginine vasopressin receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q14.2
Summary	The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008].
Disorder MIM:	600821

mRNA and Protein(s)

mRNA	Protein	Name
NM_000706.5	NP_000697.1	vasopressin V1a receptor
NM_000706.4	NP_000697.1	vasopressin V1a receptor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	AVPR1A	XP_001116798.2
Canis lupus familiaris (dog)	AVPR1A	NP_001185587.1
Danio rerio (zebrafish)	LOC571591	XP_700287.2
Homo sapiens (human)	AVPR1A	NP_000697.1
Mus musculus (house mouse)	Avpr1a	NP_058543.2
Gallus gallus (chicken)	AVPR1A	NP_001103908.1
Caenorhabditis elegans (roundworm)	CELE_T07D10.2	NP_493193.1
Pan troglodytes (chimpanzee)	AVPR1A	XP_003952184.1
Rattus norvegicus (Norway rat)	Avpr1a	NP_444178.2
Caenorhabditis elegans (roundworm)	F14F4.1	NP_510477.1
Bos taurus (cattle)	AVPR1A	NP_001098460.1
Danio rerio (zebrafish)	avpr1b	XP_683692.1
Xenopus tropicalis (tropical clawed frog)	avpr1a	XP_002931664.1

Gene Ontology
Bibliography

Related articles in PubMed

Hyper-methylation of AVPR1A and PKCΒ gene associated with insensitivity to arginine vasopressin in human pre-eclamptic placental vasculature.
Gao Q, Li H, Ding H, Fan X, Xu T, Tang J, Liu Y, Chen X, Zhou X, Tao J, Xu Z
EBioMedicine44574-581(2019 Jun)

Beyond romance: Neural and genetic correlates of altruism in pair-bonds.
Acevedo BP, Poulin MJ, Brown LL
Behavioral neuroscience133(1)18-31(2019 Feb)

Associations between neurochemical receptor genes, 2D:4D, impulsivity and relationship quality.
Pearce E, Wlodarski R, Machin A, Dunbar RIM
Biology letters14(12)(2018 12)

Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors.
Landefeld CC, Hodgkinson CA, Spagnolo PA, Marietta CA, Shen PH, Sun H, Zhou Z, Lipska BK, Goldman D
Translational psychiatry8(1)72(2018 03)

Identification and functional characterization of arginine vasopressin receptor 1A : atypical chemokine receptor 3 heteromers in vascular smooth muscle.
Albee LJ, LaPorte HM, Gao X, Eby JM, Cheng YH, Nevins AM, Volkman BF, Gaponenko V, Majetschak M
Open biology8(1)(2018 01)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AVPR1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AVPR1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21816	NM_000706.5 Latest version!	Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu21816	NM_000706.4	Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AVPR1A ( NM_000706.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000697.1 Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA.

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CloneID	OHu21816
Clone ID Related Accession (Same CDS sequence)	NM_000706.5 , NM_000706.4
Accession Version	NM_000706.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576684800000
Organism	Homo sapiens(human)
Product	vasopressin V1a receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC135584.2, AF101725.1 and AA533159.1. On Aug 14, 2019 this sequence version replaced NM_000706.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.90892.1, SRR1803614.273592.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID: 8838314) RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCGTCTCT CCGCCGGTCC CGACGCGGGG CCCTCGGGCA ACTCCAGCCC ATGGTGGCCT 
CTGGCCACCG GCGCTGGCAA CACAAGCCGG GAGGCCGAAG CCCTCGGGGA GGGCAACGGC 
CCACCGAGGG ACGTGCGCAA CGAGGAGCTG GCCAAACTGG AGATCGCCGT GCTGGCGGTG 
ACTTTCGCGG TGGCCGTGCT GGGCAACAGC AGCGTACTGC TGGCTCTGCA CCGGACGCCG 
CGCAAGACGT CCCGCATGCA CCTCTTCATC CGACACCTCA GCCTGGCCGA CCTGGCCGTG 
GCATTCTTCC AGGTGCTGCC GCAAATGTGC TGGGACATCA CCTACCGCTT CCGCGGCCCC 
GACTGGCTGT GCCGCGTGGT GAAGCACCTG CAGGTGTTCG GCATGTTTGC GTCGGCCTAC 
ATGCTGGTAG TCATGACAGC CGACCGCTAC ATCGCGGTGT GCCACCCGCT CAAGACTCTG 
CAACAGCCCG CGCGCCGCTC GCGCCTCATG ATCGCGGCCG CCTGGGTGCT GAGCTTCGTG 
CTGAGCACGC CGCAGTACTT CGTCTTCTCC ATGATCGAGG TGAACAATGT CACCAAGGCC 
CGCGACTGCT GGGCCACCTT CATCCAGCCC TGGGGTTCTC GTGCCTACGT GACCTGGATG 
ACGGGCGGCA TCTTTGTGGC GCCCGTGGTC ATCTTGGGTA CCTGCTACGG CTTCATCTGC 
TACAACATCT GGTGCAACGT CCGCGGGAAG ACGGCGTCGC GCCAGAGCAA GGGTGCAGAG 
CAAGCGGGTG TGGCCTTCCA AAAGGGGTTC CTGCTCGCAC CCTGTGTCAG CAGCGTGAAG 
TCCATTTCCC GGGCCAAGAT CCGCACGGTG AAGATGACTT TTGTGATCGT GACGGCTTAC 
ATCGTCTGCT GGGCGCCTTT CTTCATCATC CAGATGTGGT CTGTCTGGGA TCCCATGTCC 
GTCTGGACCG AATCGGAAAA CCCTACCATC ACCATCACTG CATTACTGGG TTCCTTGAAT 
AGCTGCTGTA ATCCCTGGAT ATACATGTTT TTTAGTGGCC ATCTCCTTCA AGACTGTGTT 
CAAAGCTTCC CATGCTGCCA AAACATGAAG GAAAAATTCA ACAAAGAAGA TACTGACAGT 
ATGAGCAGAA GACAGACTTT TTATTCTAAC AATCGAAGCC CAACAAACAG TACGGGTATG 
TGGAAGGACT CGCCTAAATC TTCCAAGTCC ATCAAATTCA TTCCTGTTTC AACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000697.1
CDS	366..1622
Translation	MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST

Target ORF information:

RefSeq Version	NM_000706.5
Organism	Homo sapiens(human)
Definition	Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000706.5

ORF Insert Sequence:

ATGCGTCTCT CCGCCGGTCC CGACGCGGGG CCCTCGGGCA ACTCCAGCCC ATGGTGGCCT 
CTGGCCACCG GCGCTGGCAA CACAAGCCGG GAGGCCGAAG CCCTCGGGGA GGGCAACGGC 
CCACCGAGGG ACGTGCGCAA CGAGGAGCTG GCCAAACTGG AGATCGCCGT GCTGGCGGTG 
ACTTTCGCGG TGGCCGTGCT GGGCAACAGC AGCGTACTGC TGGCTCTGCA CCGGACGCCG 
CGCAAGACGT CCCGCATGCA CCTCTTCATC CGACACCTCA GCCTGGCCGA CCTGGCCGTG 
GCATTCTTCC AGGTGCTGCC GCAAATGTGC TGGGACATCA CCTACCGCTT CCGCGGCCCC 
GACTGGCTGT GCCGCGTGGT GAAGCACCTG CAGGTGTTCG GCATGTTTGC GTCGGCCTAC 
ATGCTGGTAG TCATGACAGC CGACCGCTAC ATCGCGGTGT GCCACCCGCT CAAGACTCTG 
CAACAGCCCG CGCGCCGCTC GCGCCTCATG ATCGCGGCCG CCTGGGTGCT GAGCTTCGTG 
CTGAGCACGC CGCAGTACTT CGTCTTCTCC ATGATCGAGG TGAACAATGT CACCAAGGCC 
CGCGACTGCT GGGCCACCTT CATCCAGCCC TGGGGTTCTC GTGCCTACGT GACCTGGATG 
ACGGGCGGCA TCTTTGTGGC GCCCGTGGTC ATCTTGGGTA CCTGCTACGG CTTCATCTGC 
TACAACATCT GGTGCAACGT CCGCGGGAAG ACGGCGTCGC GCCAGAGCAA GGGTGCAGAG 
CAAGCGGGTG TGGCCTTCCA AAAGGGGTTC CTGCTCGCAC CCTGTGTCAG CAGCGTGAAG 
TCCATTTCCC GGGCCAAGAT CCGCACGGTG AAGATGACTT TTGTGATCGT GACGGCTTAC 
ATCGTCTGCT GGGCGCCTTT CTTCATCATC CAGATGTGGT CTGTCTGGGA TCCCATGTCC 
GTCTGGACCG AATCGGAAAA CCCTACCATC ACCATCACTG CATTACTGGG TTCCTTGAAT 
AGCTGCTGTA ATCCCTGGAT ATACATGTTT TTTAGTGGCC ATCTCCTTCA AGACTGTGTT 
CAAAGCTTCC CATGCTGCCA AAACATGAAG GAAAAATTCA ACAAAGAAGA TACTGACAGT 
ATGAGCAGAA GACAGACTTT TTATTCTAAC AATCGAAGCC CAACAAACAG TACGGGTATG 
TGGAAGGACT CGCCTAAATC TTCCAAGTCC ATCAAATTCA TTCCTGTTTC AACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AVPR1A ( NM_000706.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000697.1 Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA.

Price & Availability↑

CloneID	OHu21816
Clone ID Related Accession (Same CDS sequence)	NM_000706.5 , NM_000706.4
Accession Version	NM_000706.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556553600000
Organism	Homo sapiens(human)
Product	vasopressin V1a receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC135584.2, AF101725.1 and AA533159.1. On Jul 3, 2012 this sequence version replaced NM_000706.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.90892.1, SRR1803613.94958.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID: 8838314) RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 5' end.

ATGCGTCTCT CCGCCGGTCC CGACGCGGGG CCCTCGGGCA ACTCCAGCCC ATGGTGGCCT 
CTGGCCACCG GCGCTGGCAA CACAAGCCGG GAGGCCGAAG CCCTCGGGGA GGGCAACGGC 
CCACCGAGGG ACGTGCGCAA CGAGGAGCTG GCCAAACTGG AGATCGCCGT GCTGGCGGTG 
ACTTTCGCGG TGGCCGTGCT GGGCAACAGC AGCGTACTGC TGGCTCTGCA CCGGACGCCG 
CGCAAGACGT CCCGCATGCA CCTCTTCATC CGACACCTCA GCCTGGCCGA CCTGGCCGTG 
GCATTCTTCC AGGTGCTGCC GCAAATGTGC TGGGACATCA CCTACCGCTT CCGCGGCCCC 
GACTGGCTGT GCCGCGTGGT GAAGCACCTG CAGGTGTTCG GCATGTTTGC GTCGGCCTAC 
ATGCTGGTAG TCATGACAGC CGACCGCTAC ATCGCGGTGT GCCACCCGCT CAAGACTCTG 
CAACAGCCCG CGCGCCGCTC GCGCCTCATG ATCGCGGCCG CCTGGGTGCT GAGCTTCGTG 
CTGAGCACGC CGCAGTACTT CGTCTTCTCC ATGATCGAGG TGAACAATGT CACCAAGGCC 
CGCGACTGCT GGGCCACCTT CATCCAGCCC TGGGGTTCTC GTGCCTACGT GACCTGGATG 
ACGGGCGGCA TCTTTGTGGC GCCCGTGGTC ATCTTGGGTA CCTGCTACGG CTTCATCTGC 
TACAACATCT GGTGCAACGT CCGCGGGAAG ACGGCGTCGC GCCAGAGCAA GGGTGCAGAG 
CAAGCGGGTG TGGCCTTCCA AAAGGGGTTC CTGCTCGCAC CCTGTGTCAG CAGCGTGAAG 
TCCATTTCCC GGGCCAAGAT CCGCACGGTG AAGATGACTT TTGTGATCGT GACGGCTTAC 
ATCGTCTGCT GGGCGCCTTT CTTCATCATC CAGATGTGGT CTGTCTGGGA TCCCATGTCC 
GTCTGGACCG AATCGGAAAA CCCTACCATC ACCATCACTG CATTACTGGG TTCCTTGAAT 
AGCTGCTGTA ATCCCTGGAT ATACATGTTT TTTAGTGGCC ATCTCCTTCA AGACTGTGTT 
CAAAGCTTCC CATGCTGCCA AAACATGAAG GAAAAATTCA ACAAAGAAGA TACTGACAGT 
ATGAGCAGAA GACAGACTTT TTATTCTAAC AATCGAAGCC CAACAAACAG TACGGGTATG 
TGGAAGGACT CGCCTAAATC TTCCAAGTCC ATCAAATTCA TTCCTGTTTC AACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000697.1
CDS	1975..3231
Translation	MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST

Target ORF information:

RefSeq Version	NM_000706.4
Organism	Homo sapiens(human)
Definition	Homo sapiens arginine vasopressin receptor 1A (AVPR1A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000706.4

ORF Insert Sequence:

ATGCGTCTCT CCGCCGGTCC CGACGCGGGG CCCTCGGGCA ACTCCAGCCC ATGGTGGCCT 
CTGGCCACCG GCGCTGGCAA CACAAGCCGG GAGGCCGAAG CCCTCGGGGA GGGCAACGGC 
CCACCGAGGG ACGTGCGCAA CGAGGAGCTG GCCAAACTGG AGATCGCCGT GCTGGCGGTG 
ACTTTCGCGG TGGCCGTGCT GGGCAACAGC AGCGTACTGC TGGCTCTGCA CCGGACGCCG 
CGCAAGACGT CCCGCATGCA CCTCTTCATC CGACACCTCA GCCTGGCCGA CCTGGCCGTG 
GCATTCTTCC AGGTGCTGCC GCAAATGTGC TGGGACATCA CCTACCGCTT CCGCGGCCCC 
GACTGGCTGT GCCGCGTGGT GAAGCACCTG CAGGTGTTCG GCATGTTTGC GTCGGCCTAC 
ATGCTGGTAG TCATGACAGC CGACCGCTAC ATCGCGGTGT GCCACCCGCT CAAGACTCTG 
CAACAGCCCG CGCGCCGCTC GCGCCTCATG ATCGCGGCCG CCTGGGTGCT GAGCTTCGTG 
CTGAGCACGC CGCAGTACTT CGTCTTCTCC ATGATCGAGG TGAACAATGT CACCAAGGCC 
CGCGACTGCT GGGCCACCTT CATCCAGCCC TGGGGTTCTC GTGCCTACGT GACCTGGATG 
ACGGGCGGCA TCTTTGTGGC GCCCGTGGTC ATCTTGGGTA CCTGCTACGG CTTCATCTGC 
TACAACATCT GGTGCAACGT CCGCGGGAAG ACGGCGTCGC GCCAGAGCAA GGGTGCAGAG 
CAAGCGGGTG TGGCCTTCCA AAAGGGGTTC CTGCTCGCAC CCTGTGTCAG CAGCGTGAAG 
TCCATTTCCC GGGCCAAGAT CCGCACGGTG AAGATGACTT TTGTGATCGT GACGGCTTAC 
ATCGTCTGCT GGGCGCCTTT CTTCATCATC CAGATGTGGT CTGTCTGGGA TCCCATGTCC 
GTCTGGACCG AATCGGAAAA CCCTACCATC ACCATCACTG CATTACTGGG TTCCTTGAAT 
AGCTGCTGTA ATCCCTGGAT ATACATGTTT TTTAGTGGCC ATCTCCTTCA AGACTGTGTT 
CAAAGCTTCC CATGCTGCCA AAACATGAAG GAAAAATTCA ACAAAGAAGA TACTGACAGT 
ATGAGCAGAA GACAGACTTT TTATTCTAAC AATCGAAGCC CAACAAACAG TACGGGTATG 
TGGAAGGACT CGCCTAAATC TTCCAAGTCC ATCAAATTCA TTCCTGTTTC AACTTGA