CENPQ cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CENPQ
Entrez Gene ID	55166
Full Name	centromere protein Q
Synonyms	C6orf139,CENP-Q
General protein information	Preferred Names centromere protein Q Names centromere protein Q
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p12.3
Summary	CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008].
Disorder MIM:	611506

mRNA and Protein(s)

mRNA	Protein	Name
NM_018132.4	NP_060602.2	centromere protein Q
XM_011514723.2	XP_011513025.2	centromere protein Q isoform X1
NM_018132.3	NP_060602.2	centromere protein Q
XM_005249205.1	XP_005249262.1	centromere protein Q isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cenpq	NP_114069.1
Gallus gallus (chicken)	CENPQ	NP_001038114.1
Pan troglodytes (chimpanzee)	CENPQ	XP_003311370.1
Danio rerio (zebrafish)	LOC101885540	XP_005168071.1
Homo sapiens (human)	CENPQ	NP_060602.2
Bos taurus (cattle)	CENPQ	NP_001071533.1
Canis lupus familiaris (dog)	CENPQ	XP_532165.3
Macaca mulatta (Rhesus monkey)	LOC721027	XP_001117023.2
Rattus norvegicus (Norway rat)	Cenpq	NP_001014237.1

Gene Ontology
Bibliography

Related articles in PubMed

Mammalian Polo-like kinase 1 (Plk1) promotes proper chromosome segregation by phosphorylating and delocalizing the PBIP1·CENP-Q complex from kinetochores.
Park CH, Park JE, Kim TS, Kang YH, Soung NK, Zhou M, Kim NH, Bang JK, Lee KS
The Journal of biological chemistry290(13)8569-81(2015 Mar)

Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways.
Bancroft J, Auckland P, Samora CP, McAinsh AD
Journal of cell science128(1)171-84(2015 Jan)

Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.
Eskat A, Deng W, Hofmeister A, Rudolphi S, Emmerth S, Hellwig D, Ulbricht T, Döring V, Bancroft JM, McAinsh AD, Cardoso MC, Meraldi P, Hoischen C, Leonhardt H, Diekmann S
PloS one7(9)e44717(2012)

Mammalian polo-like kinase 1-dependent regulation of the PBIP1-CENP-Q complex at kinetochores.
Kang YH, Park CH, Kim TS, Soung NK, Bang JK, Kim BY, Park JE, Lee KS
The Journal of biological chemistry286(22)19744-57(2011 Jun)

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.
Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T
Nature cell biology8(5)446-57(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CENPQ gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CENPQ cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu96669	XM_011514723.2 Latest version!	Homo sapiens centromere protein Q (CENPQ), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu02702	NM_018132.4 Latest version!	Homo sapiens centromere protein Q (CENPQ), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OHu02702	XM_005249205.1 Latest version!	Homo sapiens centromere protein Q (CENPQ), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
View Old Accession Versions >>
OHu02702	NM_018132.3	Homo sapiens centromere protein Q (CENPQ), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CENPQ ( XM_011514723.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011513025.2 Homo sapiens centromere protein Q (CENPQ), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu96669
Clone ID Related Accession (Same CDS sequence)	XM_011514723.2
Accession Version	XM_011514723.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	centromere protein Q isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514723.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCGTTT CCGCTTTCTT CCCACCCACT TCCGGGTCTC CTCTGTTTAC GAATGTTTGG 
GCGCGAATTA CTCTAAGCGC GGCTCTCAGA AGGGTGCAAG AAGAATCAGT GGTTAGAAAC 
ACAGTGAAAA AAAATAAAAA TCATCTGAAA GATCTGTCTT CTGAAGGACA AACAAAGCAC 
ACTAACCTAA AACACGGAAA GACAGCAGCC AGCAAGAGAA AAACCTGGCA ACCTCTGTCA 
AAGAGTACCA GAGACCATTT GCAAACTATG ATGGAATCAG TAATAATGAC AATTTTGAGT 
AACAGTATTA AAGAAAAAGA AGAAATACAA TACCATCTCA ACTTCCTGAA GAAAAGATTG 
CTACAACAGT GTGAAACTCT GAAAGTCCCT CCCAAAAAGA TGGAAGATTT AACTAATGTA 
TCAAGTCTAC TGAATATGGA AAGGGCACGA GACAAAGCTA ATGAAGAAGG TCTGGCATTA 
CTACAGGAAG AAATAGATAA AATGGTAGAG ACCACAGAGT TAATGACTGG GAATATTCAG 
AGCCTAAAGA ACAAAATTCA GATTCTGGCA AGTGAGGTGG AAGAAGAAGA GGAGAGAGTA 
AAACAGATGC ATCAAATAAA TAGTAGTGGA GTACTCTCTC TTCCGGAACT TTCTCAGAAA 
ACTCTCAAAG CACCCACACT TCAGAAAGAA ATTTTGGCGC TAATTCCAAA CCAGAATGCT 
CTTCTAAAGG ACTTGGATAT TCTTCATAAT TCATCACAGA TGAAGAGCAT GTCAACCTTC 
ATTGAAGAAG CCTATAAGAA ACTGGATGCA TCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011513025.2
CDS	17..832
Translation	MPVSAFFPPTSGSPLFTNVWARITLSAALRRVQEESVVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS

Target ORF information:

RefSeq Version	XM_011514723.2
Organism	Homo sapiens(human)
Definition	Homo sapiens centromere protein Q (CENPQ), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514723.2

ORF Insert Sequence:

ATGCCCGTTT CCGCTTTCTT CCCACCCACT TCCGGGTCTC CTCTGTTTAC GAATGTTTGG 
GCGCGAATTA CTCTAAGCGC GGCTCTCAGA AGGGTGCAAG AAGAATCAGT GGTTAGAAAC 
ACAGTGAAAA AAAATAAAAA TCATCTGAAA GATCTGTCTT CTGAAGGACA AACAAAGCAC 
ACTAACCTAA AACACGGAAA GACAGCAGCC AGCAAGAGAA AAACCTGGCA ACCTCTGTCA 
AAGAGTACCA GAGACCATTT GCAAACTATG ATGGAATCAG TAATAATGAC AATTTTGAGT 
AACAGTATTA AAGAAAAAGA AGAAATACAA TACCATCTCA ACTTCCTGAA GAAAAGATTG 
CTACAACAGT GTGAAACTCT GAAAGTCCCT CCCAAAAAGA TGGAAGATTT AACTAATGTA 
TCAAGTCTAC TGAATATGGA AAGGGCACGA GACAAAGCTA ATGAAGAAGG TCTGGCATTA 
CTACAGGAAG AAATAGATAA AATGGTAGAG ACCACAGAGT TAATGACTGG GAATATTCAG 
AGCCTAAAGA ACAAAATTCA GATTCTGGCA AGTGAGGTGG AAGAAGAAGA GGAGAGAGTA 
AAACAGATGC ATCAAATAAA TAGTAGTGGA GTACTCTCTC TTCCGGAACT TTCTCAGAAA 
ACTCTCAAAG CACCCACACT TCAGAAAGAA ATTTTGGCGC TAATTCCAAA CCAGAATGCT 
CTTCTAAAGG ACTTGGATAT TCTTCATAAT TCATCACAGA TGAAGAGCAT GTCAACCTTC 
ATTGAAGAAG CCTATAAGAA ACTGGATGCA TCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CENPQ ( NM_018132.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060602.2 Homo sapiens centromere protein Q (CENPQ), mRNA.

Price & Availability↑

CloneID	OHu02702
Clone ID Related Accession (Same CDS sequence)	NM_018132.4 , NM_018132.3 , XM_005249205.1
Accession Version	NM_018132.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	centromere protein Q
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL590668.5 and AL590244.5. On Nov 23, 2018 this sequence version replaced NM_018132.3. ##Evidence-Data-START## Transcript exon combination :: SRR5189658.77771.1, SRR3476690.1009017.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000335783.4/ ENSP00000337289.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTGGTA AAGCAAATGC TTCCAAGAAA AACGCTCAAC AGTTAAAAAG AAATCCAAAG 
AGAAAAAAGG ATAATGAGGA AGTTGTGTTG TCAGAGAATA AGGTTAGAAA CACAGTGAAA 
AAAAATAAAA ATCATCTGAA AGATCTGTCT TCTGAAGGAC AAACAAAGCA CACTAACCTA 
AAACACGGAA AGACAGCAGC CAGCAAGAGA AAAACCTGGC AACCTCTGTC AAAGAGTACC 
AGAGACCATT TGCAAACTAT GATGGAATCA GTAATAATGA CAATTTTGAG TAACAGTATT 
AAAGAAAAAG AAGAAATACA ATACCATCTC AACTTCCTGA AGAAAAGATT GCTACAACAG 
TGTGAAACTC TGAAAGTCCC TCCCAAAAAG ATGGAAGATT TAACTAATGT ATCAAGTCTA 
CTGAATATGG AAAGGGCACG AGACAAAGCT AATGAAGAAG GTCTGGCATT ACTACAGGAA 
GAAATAGATA AAATGGTAGA GACCACAGAG TTAATGACTG GGAATATTCA GAGCCTAAAG 
AACAAAATTC AGATTCTGGC AAGTGAGGTG GAAGAAGAAG AGGAGAGAGT AAAACAGATG 
CATCAAATAA ATAGTAGTGG AGTACTCTCT CTTCCGGAAC TTTCTCAGAA AACTCTCAAA 
GCACCCACAC TTCAGAAAGA AATTTTGGCG CTAATTCCAA ACCAGAATGC TCTTCTAAAG 
GACTTGGATA TTCTTCATAA TTCATCACAG ATGAAGAGCA TGTCAACCTT CATTGAAGAA 
GCCTATAAGA AACTGGATGC ATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060602.2
CDS	103..909
Translation	MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS

Target ORF information:

RefSeq Version	NM_018132.4
Organism	Homo sapiens(human)
Definition	Homo sapiens centromere protein Q (CENPQ), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018132.4

ORF Insert Sequence:

ATGTCTGGTA AAGCAAATGC TTCCAAGAAA AACGCTCAAC AGTTAAAAAG AAATCCAAAG 
AGAAAAAAGG ATAATGAGGA AGTTGTGTTG TCAGAGAATA AGGTTAGAAA CACAGTGAAA 
AAAAATAAAA ATCATCTGAA AGATCTGTCT TCTGAAGGAC AAACAAAGCA CACTAACCTA 
AAACACGGAA AGACAGCAGC CAGCAAGAGA AAAACCTGGC AACCTCTGTC AAAGAGTACC 
AGAGACCATT TGCAAACTAT GATGGAATCA GTAATAATGA CAATTTTGAG TAACAGTATT 
AAAGAAAAAG AAGAAATACA ATACCATCTC AACTTCCTGA AGAAAAGATT GCTACAACAG 
TGTGAAACTC TGAAAGTCCC TCCCAAAAAG ATGGAAGATT TAACTAATGT ATCAAGTCTA 
CTGAATATGG AAAGGGCACG AGACAAAGCT AATGAAGAAG GTCTGGCATT ACTACAGGAA 
GAAATAGATA AAATGGTAGA GACCACAGAG TTAATGACTG GGAATATTCA GAGCCTAAAG 
AACAAAATTC AGATTCTGGC AAGTGAGGTG GAAGAAGAAG AGGAGAGAGT AAAACAGATG 
CATCAAATAA ATAGTAGTGG AGTACTCTCT CTTCCGGAAC TTTCTCAGAA AACTCTCAAA 
GCACCCACAC TTCAGAAAGA AATTTTGGCG CTAATTCCAA ACCAGAATGC TCTTCTAAAG 
GACTTGGATA TTCTTCATAA TTCATCACAG ATGAAGAGCA TGTCAACCTT CATTGAAGAA 
GCCTATAAGA AACTGGATGC ATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CENPQ ( NM_018132.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060602.2 Homo sapiens centromere protein Q (CENPQ), mRNA.

Price & Availability↑

CloneID	OHu02702
Clone ID Related Accession (Same CDS sequence)	NM_018132.4 , NM_018132.3 , XM_005249205.1
Accession Version	NM_018132.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Homo sapiens(human)
Product	centromere protein Q
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI768787.1, BC016279.1, AK001407.1, AI039464.1 and AA811376.1. On Apr 7, 2004 this sequence version replaced NM_018132.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.425456.1, SRR1163655.561507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGGTA AAGCAAATGC TTCCAAGAAA AACGCTCAAC AGTTAAAAAG AAATCCAAAG 
AGAAAAAAGG ATAATGAGGA AGTTGTGTTG TCAGAGAATA AGGTTAGAAA CACAGTGAAA 
AAAAATAAAA ATCATCTGAA AGATCTGTCT TCTGAAGGAC AAACAAAGCA CACTAACCTA 
AAACACGGAA AGACAGCAGC CAGCAAGAGA AAAACCTGGC AACCTCTGTC AAAGAGTACC 
AGAGACCATT TGCAAACTAT GATGGAATCA GTAATAATGA CAATTTTGAG TAACAGTATT 
AAAGAAAAAG AAGAAATACA ATACCATCTC AACTTCCTGA AGAAAAGATT GCTACAACAG 
TGTGAAACTC TGAAAGTCCC TCCCAAAAAG ATGGAAGATT TAACTAATGT ATCAAGTCTA 
CTGAATATGG AAAGGGCACG AGACAAAGCT AATGAAGAAG GTCTGGCATT ACTACAGGAA 
GAAATAGATA AAATGGTAGA GACCACAGAG TTAATGACTG GGAATATTCA GAGCCTAAAG 
AACAAAATTC AGATTCTGGC AAGTGAGGTG GAAGAAGAAG AGGAGAGAGT AAAACAGATG 
CATCAAATAA ATAGTAGTGG AGTACTCTCT CTTCCGGAAC TTTCTCAGAA AACTCTCAAA 
GCACCCACAC TTCAGAAAGA AATTTTGGCG CTAATTCCAA ACCAGAATGC TCTTCTAAAG 
GACTTGGATA TTCTTCATAA TTCATCACAG ATGAAGAGCA TGTCAACCTT CATTGAAGAA 
GCCTATAAGA AACTGGATGC ATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060602.2
CDS	90..896
Translation	MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS

Target ORF information:

RefSeq Version	NM_018132.3
Organism	Homo sapiens(human)
Definition	Homo sapiens centromere protein Q (CENPQ), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018132.3

ORF Insert Sequence:

ATGTCTGGTA AAGCAAATGC TTCCAAGAAA AACGCTCAAC AGTTAAAAAG AAATCCAAAG 
AGAAAAAAGG ATAATGAGGA AGTTGTGTTG TCAGAGAATA AGGTTAGAAA CACAGTGAAA 
AAAAATAAAA ATCATCTGAA AGATCTGTCT TCTGAAGGAC AAACAAAGCA CACTAACCTA 
AAACACGGAA AGACAGCAGC CAGCAAGAGA AAAACCTGGC AACCTCTGTC AAAGAGTACC 
AGAGACCATT TGCAAACTAT GATGGAATCA GTAATAATGA CAATTTTGAG TAACAGTATT 
AAAGAAAAAG AAGAAATACA ATACCATCTC AACTTCCTGA AGAAAAGATT GCTACAACAG 
TGTGAAACTC TGAAAGTCCC TCCCAAAAAG ATGGAAGATT TAACTAATGT ATCAAGTCTA 
CTGAATATGG AAAGGGCACG AGACAAAGCT AATGAAGAAG GTCTGGCATT ACTACAGGAA 
GAAATAGATA AAATGGTAGA GACCACAGAG TTAATGACTG GGAATATTCA GAGCCTAAAG 
AACAAAATTC AGATTCTGGC AAGTGAGGTG GAAGAAGAAG AGGAGAGAGT AAAACAGATG 
CATCAAATAA ATAGTAGTGG AGTACTCTCT CTTCCGGAAC TTTCTCAGAA AACTCTCAAA 
GCACCCACAC TTCAGAAAGA AATTTTGGCG CTAATTCCAA ACCAGAATGC TCTTCTAAAG 
GACTTGGATA TTCTTCATAA TTCATCACAG ATGAAGAGCA TGTCAACCTT CATTGAAGAA 
GCCTATAAGA AACTGGATGC ATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CENPQ ( XM_005249205.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249262.1 Homo sapiens centromere protein Q (CENPQ), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu02702
Clone ID Related Accession (Same CDS sequence)	NM_018132.4 , NM_018132.3 , XM_005249205.1
Accession Version	XM_005249205.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	centromere protein Q isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGGTA AAGCAAATGC TTCCAAGAAA AACGCTCAAC AGTTAAAAAG AAATCCAAAG 
AGAAAAAAGG ATAATGAGGA AGTTGTGTTG TCAGAGAATA AGGTTAGAAA CACAGTGAAA 
AAAAATAAAA ATCATCTGAA AGATCTGTCT TCTGAAGGAC AAACAAAGCA CACTAACCTA 
AAACACGGAA AGACAGCAGC CAGCAAGAGA AAAACCTGGC AACCTCTGTC AAAGAGTACC 
AGAGACCATT TGCAAACTAT GATGGAATCA GTAATAATGA CAATTTTGAG TAACAGTATT 
AAAGAAAAAG AAGAAATACA ATACCATCTC AACTTCCTGA AGAAAAGATT GCTACAACAG 
TGTGAAACTC TGAAAGTCCC TCCCAAAAAG ATGGAAGATT TAACTAATGT ATCAAGTCTA 
CTGAATATGG AAAGGGCACG AGACAAAGCT AATGAAGAAG GTCTGGCATT ACTACAGGAA 
GAAATAGATA AAATGGTAGA GACCACAGAG TTAATGACTG GGAATATTCA GAGCCTAAAG 
AACAAAATTC AGATTCTGGC AAGTGAGGTG GAAGAAGAAG AGGAGAGAGT AAAACAGATG 
CATCAAATAA ATAGTAGTGG AGTACTCTCT CTTCCGGAAC TTTCTCAGAA AACTCTCAAA 
GCACCCACAC TTCAGAAAGA AATTTTGGCG CTAATTCCAA ACCAGAATGC TCTTCTAAAG 
GACTTGGATA TTCTTCATAA TTCATCACAG ATGAAGAGCA TGTCAACCTT CATTGAAGAA 
GCCTATAAGA AACTGGATGC ATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249262.1
CDS	151..957
Translation	MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS

Target ORF information:

RefSeq Version	XM_005249205.1
Organism	Homo sapiens(human)
Definition	Homo sapiens centromere protein Q (CENPQ), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005249205.1

ORF Insert Sequence:

ATGTCTGGTA AAGCAAATGC TTCCAAGAAA AACGCTCAAC AGTTAAAAAG AAATCCAAAG 
AGAAAAAAGG ATAATGAGGA AGTTGTGTTG TCAGAGAATA AGGTTAGAAA CACAGTGAAA 
AAAAATAAAA ATCATCTGAA AGATCTGTCT TCTGAAGGAC AAACAAAGCA CACTAACCTA 
AAACACGGAA AGACAGCAGC CAGCAAGAGA AAAACCTGGC AACCTCTGTC AAAGAGTACC 
AGAGACCATT TGCAAACTAT GATGGAATCA GTAATAATGA CAATTTTGAG TAACAGTATT 
AAAGAAAAAG AAGAAATACA ATACCATCTC AACTTCCTGA AGAAAAGATT GCTACAACAG 
TGTGAAACTC TGAAAGTCCC TCCCAAAAAG ATGGAAGATT TAACTAATGT ATCAAGTCTA 
CTGAATATGG AAAGGGCACG AGACAAAGCT AATGAAGAAG GTCTGGCATT ACTACAGGAA 
GAAATAGATA AAATGGTAGA GACCACAGAG TTAATGACTG GGAATATTCA GAGCCTAAAG 
AACAAAATTC AGATTCTGGC AAGTGAGGTG GAAGAAGAAG AGGAGAGAGT AAAACAGATG 
CATCAAATAA ATAGTAGTGG AGTACTCTCT CTTCCGGAAC TTTCTCAGAA AACTCTCAAA 
GCACCCACAC TTCAGAAAGA AATTTTGGCG CTAATTCCAA ACCAGAATGC TCTTCTAAAG 
GACTTGGATA TTCTTCATAA TTCATCACAG ATGAAGAGCA TGTCAACCTT CATTGAAGAA 
GCCTATAAGA AACTGGATGC ATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mammalian Polo-like kinase 1 (Plk1) promotes proper chromosome segregation by phosphorylating and delocalizing the PBIP1·CENP-Q complex from kinetochores.
The Journal of biological chemistry290(13)8569-81(2015 Mar)
Park CH,Park JE,Kim TS,Kang YH,Soung NK,Zhou M,Kim NH,Bang JK,Lee KS

Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways.
Journal of cell science128(1)171-84(2015 Jan)
Bancroft J,Auckland P,Samora CP,McAinsh AD

Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.
PloS one7(9)e44717(2012)
Eskat A,Deng W,Hofmeister A,Rudolphi S,Emmerth S,Hellwig D,Ulbricht T,Döring V,Bancroft JM,McAinsh AD,Cardoso MC,Meraldi P,Hoischen C,Leonhardt H,Diekmann S

Mammalian polo-like kinase 1-dependent regulation of the PBIP1-CENP-Q complex at kinetochores.
The Journal of biological chemistry286(22)19744-57(2011 Jun)
Kang YH,Park CH,Kim TS,Soung NK,Bang JK,Kim BY,Park JE,Lee KS

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.
Nature cell biology8(5)446-57(2006 May)
Okada M,Cheeseman IM,Hori T,Okawa K,McLeod IX,Yates JR 3rd,Desai A,Fukagawa T

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

CENPQ cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM