PKD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PKD2
Entrez Gene ID	5311
Full Name	polycystin 2, transient receptor potential cation channel
Synonyms	APKD2,PC2,PKD4,Pc-2,TRPP2
General protein information	Preferred Names polycystin 2, transient receptor potential cation channel Names polycystin-2 autosomal dominant polycystic kidney disease type II protein polycystic kidney disease 2 (autosomal dominant) transient receptor potential cation channel subfamily P member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q22.1
Summary	This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011].
Disorder MIM:	173910
Disorder Html:	Polycystic kidney disease 2, 613095 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000297.4	NP_000288.1	polycystin-2
NM_000297.3	NP_000288.1	polycystin-2
XM_011532028.2	XP_011530330.1	polycystin-2 isoform X1
XM_011532029.1	XP_011530331.1	polycystin-2 isoform X2
XM_011532030.2	XP_011530332.1	polycystin-2 isoform X3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PKD2	XP_003310458.1
Macaca mulatta (Rhesus monkey)	PKD2	XP_001099242.1
Mus musculus (house mouse)	Pkd2	NP_032887.3
Bos taurus (cattle)	PKD2	NP_001039777.1
Gallus gallus (chicken)	PKD2	NP_001026311.1
Canis lupus familiaris (dog)	PKD2	XP_544974.2
Xenopus tropicalis (tropical clawed frog)	pkd2	XP_002938673.2
Homo sapiens (human)	PKD2	NP_000288.1
Rattus norvegicus (Norway rat)	Pkd2	NP_001178863.1
Danio rerio (zebrafish)	pkd2	NP_001002310.1
Caenorhabditis elegans (roundworm)	pkd-2	NP_502838.3

Gene Ontology
Bibliography

Related articles in PubMed

A role for polycystin-1 and polycystin-2 in neural progenitor cell differentiation.
Winokurow N, Schumacher S
Cellular and molecular life sciences : CMLS76(14)2851-2869(2019 Jul)

Identification of PKD1 and PKD2 gene variants in a cohort of 125 Asian Indian patients of ADPKD.
Pandita S, Ramachandran V, Balakrishnan P, Rolfs A, Brandau O, Eichler S, Bhalla AK, Khullar D, Amitabh V, Ramanarayanan S, Kher V, Verma J, Kohli S, Saxena R, Verma IC
Journal of human genetics64(5)409-419(2019 May)

Polycystins and Mechanotransduction in Human Disease.
Gargalionis AN, Basdra EK, Papavassiliou AG
International journal of molecular sciences20(9)(2019 May)

The Polycystin Complex Reveals Its Complexity.
Padovano V, Caplan MJ
Biochemistry57(51)6917-6918(2018 12)

MicroRNA-106b-5p regulates cisplatin chemosensitivity by targeting polycystic kidney disease-2 in non-small-cell lung cancer.
Yu S, Qin X, Chen T, Zhou L, Xu X, Feng J
Anti-cancer drugs28(8)852-860(2017 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PKD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PKD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26897	NM_000297.4 Latest version!	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu59727	XM_011532028.2 Latest version!	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu59728	XM_011532029.1 Latest version!	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu59729	XM_011532030.2 Latest version!	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu26897	NM_000297.3	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PKD2 ( NM_000297.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000288.1 Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26897
Clone ID Related Accession (Same CDS sequence)	NM_000297.4 , NM_000297.3
Accession Version	NM_000297.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2907bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1567353600000
Organism	Homo sapiens(human)
Product	polycystin-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC084732.1, BC112263.1, AF054992.1, AF113693.1 and AW600307.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000297.3. Transcript Variant: This variant (1) represents the longer transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U50928.1, BC112261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000237596.7/ ENSP00000237596.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGAACT CCAGTCGCGT GCAGCCTCAG CAGCCCGGGG ACGCCAAGCG GCCGCCCGCG 
CCCCGCGCGC CGGACCCGGG CCGGCTGATG GCTGGCTGCG CGGCCGTGGG CGCCAGCCTC 
GCCGCCCCGG GCGGCCTCTG CGAGCAGCGG GGCCTGGAGA TCGAGATGCA GCGCATCCGG 
CAGGCGGCCG CGCGGGACCC CCCGGCCGGA GCCGCGGCCT CCCCTTCTCC TCCGCTCTCG 
TCGTGCTCCC GGCAGGCGTG GAGCCGCGAT AACCCCGGCT TCGAGGCCGA GGAGGAGGAG 
GAGGAGGTGG AAGGGGAAGA AGGCGGAATG GTGGTGGAGA TGGACGTAGA GTGGCGCCCG 
GGCAGCCGGA GGTCGGCCGC CTCCTCGGCC GTGAGCTCCG TGGGCGCGCG GAGCCGGGGG 
CTTGGGGGCT ACCACGGCGC GGGCCACCCG AGCGGGAGGC GGCGCCGGCG AGAGGACCAG 
GGCCCGCCGT GCCCCAGCCC AGTCGGCGGC GGGGACCCGC TGCATCGCCA CCTCCCCCTG 
GAAGGGCAGC CGCCCCGAGT GGCCTGGGCG GAGAGGCTGG TTCGCGGGCT GCGAGGTCTC 
TGGGGAACAA GACTCATGGA GGAAAGCAGC ACTAACCGAG AGAAATACCT TAAAAGTGTT 
TTACGGGAAC TGGTCACATA CCTCCTTTTT CTCATAGTCT TGTGCATCTT GACCTACGGC 
ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000288.1
CDS	100..3006
Translation	MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLCEQRGLEIEMQRIRQAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRPGSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPLEGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV

Target ORF information:

RefSeq Version	NM_000297.4
Organism	Homo sapiens(human)
Definition	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000297.4

ORF Insert Sequence:

ATGGTGAACT CCAGTCGCGT GCAGCCTCAG CAGCCCGGGG ACGCCAAGCG GCCGCCCGCG 
CCCCGCGCGC CGGACCCGGG CCGGCTGATG GCTGGCTGCG CGGCCGTGGG CGCCAGCCTC 
GCCGCCCCGG GCGGCCTCTG CGAGCAGCGG GGCCTGGAGA TCGAGATGCA GCGCATCCGG 
CAGGCGGCCG CGCGGGACCC CCCGGCCGGA GCCGCGGCCT CCCCTTCTCC TCCGCTCTCG 
TCGTGCTCCC GGCAGGCGTG GAGCCGCGAT AACCCCGGCT TCGAGGCCGA GGAGGAGGAG 
GAGGAGGTGG AAGGGGAAGA AGGCGGAATG GTGGTGGAGA TGGACGTAGA GTGGCGCCCG 
GGCAGCCGGA GGTCGGCCGC CTCCTCGGCC GTGAGCTCCG TGGGCGCGCG GAGCCGGGGG 
CTTGGGGGCT ACCACGGCGC GGGCCACCCG AGCGGGAGGC GGCGCCGGCG AGAGGACCAG 
GGCCCGCCGT GCCCCAGCCC AGTCGGCGGC GGGGACCCGC TGCATCGCCA CCTCCCCCTG 
GAAGGGCAGC CGCCCCGAGT GGCCTGGGCG GAGAGGCTGG TTCGCGGGCT GCGAGGTCTC 
TGGGGAACAA GACTCATGGA GGAAAGCAGC ACTAACCGAG AGAAATACCT TAAAAGTGTT 
TTACGGGAAC TGGTCACATA CCTCCTTTTT CTCATAGTCT TGTGCATCTT GACCTACGGC 
ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKD2 ( NM_000297.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000288.1 Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), mRNA.

Price & Availability↑

CloneID	OHu26897
Clone ID Related Accession (Same CDS sequence)	NM_000297.4 , NM_000297.3
Accession Version	NM_000297.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2907bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512835200000
Organism	Homo sapiens(human)
Product	polycystin-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC112263.1, AF054992.1, AF113693.1 and AW600307.1. This sequence is a reference standard in the RefSeqGene project. On Mar 3, 2011 this sequence version replaced NM_000297.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC112261.1, U50928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGAACT CCAGTCGCGT GCAGCCTCAG CAGCCCGGGG ACGCCAAGCG GCCGCCCGCG 
CCCCGCGCGC CGGACCCGGG CCGGCTGATG GCTGGCTGCG CGGCCGTGGG CGCCAGCCTC 
GCCGCCCCGG GCGGCCTCTG CGAGCAGCGG GGCCTGGAGA TCGAGATGCA GCGCATCCGG 
CAGGCGGCCG CGCGGGACCC CCCGGCCGGA GCCGCGGCCT CCCCTTCTCC TCCGCTCTCG 
TCGTGCTCCC GGCAGGCGTG GAGCCGCGAT AACCCCGGCT TCGAGGCCGA GGAGGAGGAG 
GAGGAGGTGG AAGGGGAAGA AGGCGGAATG GTGGTGGAGA TGGACGTAGA GTGGCGCCCG 
GGCAGCCGGA GGTCGGCCGC CTCCTCGGCC GTGAGCTCCG TGGGCGCGCG GAGCCGGGGG 
CTTGGGGGCT ACCACGGCGC GGGCCACCCG AGCGGGAGGC GGCGCCGGCG AGAGGACCAG 
GGCCCGCCGT GCCCCAGCCC AGTCGGCGGC GGGGACCCGC TGCATCGCCA CCTCCCCCTG 
GAAGGGCAGC CGCCCCGAGT GGCCTGGGCG GAGAGGCTGG TTCGCGGGCT GCGAGGTCTC 
TGGGGAACAA GACTCATGGA GGAAAGCAGC ACTAACCGAG AGAAATACCT TAAAAGTGTT 
TTACGGGAAC TGGTCACATA CCTCCTTTTT CTCATAGTCT TGTGCATCTT GACCTACGGC 
ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000288.1
CDS	88..2994
Translation	MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLCEQRGLEIEMQRIRQAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRPGSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPLEGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV

Target ORF information:

RefSeq Version	NM_000297.3
Organism	Homo sapiens(human)
Definition	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000297.3

ORF Insert Sequence:

ATGGTGAACT CCAGTCGCGT GCAGCCTCAG CAGCCCGGGG ACGCCAAGCG GCCGCCCGCG 
CCCCGCGCGC CGGACCCGGG CCGGCTGATG GCTGGCTGCG CGGCCGTGGG CGCCAGCCTC 
GCCGCCCCGG GCGGCCTCTG CGAGCAGCGG GGCCTGGAGA TCGAGATGCA GCGCATCCGG 
CAGGCGGCCG CGCGGGACCC CCCGGCCGGA GCCGCGGCCT CCCCTTCTCC TCCGCTCTCG 
TCGTGCTCCC GGCAGGCGTG GAGCCGCGAT AACCCCGGCT TCGAGGCCGA GGAGGAGGAG 
GAGGAGGTGG AAGGGGAAGA AGGCGGAATG GTGGTGGAGA TGGACGTAGA GTGGCGCCCG 
GGCAGCCGGA GGTCGGCCGC CTCCTCGGCC GTGAGCTCCG TGGGCGCGCG GAGCCGGGGG 
CTTGGGGGCT ACCACGGCGC GGGCCACCCG AGCGGGAGGC GGCGCCGGCG AGAGGACCAG 
GGCCCGCCGT GCCCCAGCCC AGTCGGCGGC GGGGACCCGC TGCATCGCCA CCTCCCCCTG 
GAAGGGCAGC CGCCCCGAGT GGCCTGGGCG GAGAGGCTGG TTCGCGGGCT GCGAGGTCTC 
TGGGGAACAA GACTCATGGA GGAAAGCAGC ACTAACCGAG AGAAATACCT TAAAAGTGTT 
TTACGGGAAC TGGTCACATA CCTCCTTTTT CTCATAGTCT TGTGCATCTT GACCTACGGC 
ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKD2 ( XM_011532028.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530330.1 Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu59727
Clone ID Related Accession (Same CDS sequence)	XM_011532028.2
Accession Version	XM_011532028.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2682bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	polycystin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532028.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGAACT CCAGTCGCGT GCAGCCTCAG CAGCCCGGGG ACGCCAAGCG GCCGCCCGCG 
CCCCGCGCGC CGGACCCGGG CCGGCTGATG GCTGGCTGCG CGGCCGTGGG CGCCAGCCTC 
GCCGCCCCGG GCGGCCTCTG CGAGCAGCGG GGCCTGGAGA TCGAGATGCA GCGCATCCGG 
CAGGCGGCCG CGCGGGACCC CCCGGCCGGA GCCGCGGCCT CCCCTTCTCC TCCGCTCTCG 
TCGTGCTCCC GGCAGGCGTG GAGCCGCGAT AACCCCGGCT TCGAGGCCGA GGAGGAGGAG 
GAGGAGGTGG AAGGGGAAGA AGGCGGAATG GTGGTGGAGA TGGACGTAGA GTGGCGCCCG 
GGCAGCCGGA GGTCGGCCGC CTCCTCGGCC GTGAGCTCCG TGGGCGCGCG GAGCCGGGGG 
CTTGGGGGCT ACCACGGCGC GGGCCACCCG AGCGGGAGGC GGCGCCGGCG AGAGGACCAG 
GGCCCGCCGT GCCCCAGCCC AGTCGGCGGC GGGGACCCGC TGCATCGCCA CCTCCCCCTG 
GAAGGGCAGC CGCCCCGAGT GGCCTGGGCG GAGAGGCTGG TTCGCGGGCT GCGAGGTCTC 
TGGGGAACAA GACTCATGGA GGAAAGCAGC ACTAACCGAG AGAAATACCT TAAAAGTGTT 
TTACGGGAAC TGGTCACATA CCTCCTTTTT CTCATAGTCT TGTGCATCTT GACCTACGGC 
ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCGTTATT GGTTGAATTC CCAGCAACAG GTGGTGTGAT TCCATCTTGG 
CAATTTCAGC CTTTAAAGCT GATCCGATAT GTCACAACTT TTGATTTCTT CCTGGCAGCC 
TGTGAGATTA TCTTTTGTTT CTTTATCTTT TACTATGTGG TGGAAGAGAT ATTGGAAATT 
CGCATTCACA AACTACACTA TTTCAGGAGT TTCTGGAATT GTCTGGATGT TGTGATCGTT 
GTGCTGTCAG TGGTAGCTAT AGGAATTAAC ATATACAGAA CATCAAATGT GGAGGTGCTA 
CTACAGTTTC TGGAAGATCA AAATACTTTC CCCAACTTTG AGCATCTGGC ATATTGGCAG 
ATACAGTTCA ACAATATAGC TGCTGTCACA GTATTTTTTG TCTGGATTAA GCTCTTCAAA 
TTCATCAATT TTAACAGGAC CATGAGCCAG CTCTCGACAA CCATGTCTCG ATGTGCCAAA 
GACCTGTTTG GCTTTGCTAT TATGTTCTTC ATTATTTTCC TAGCGTATGC TCAGTTGGCA 
TACCTTGTCT TTGGCACTCA GGTCGATGAC TTCAGTACTT TCCAAGAGTG TATCTTCACT 
CAATTCCGTA TCATTTTGGG CGATATCAAC TTTGCAGAGA TTGAGGAAGC TAATCGAGTT 
TTGGGACCAA TTTATTTCAC TACATTTGTG TTCTTTATGT TCTTCATTCT TTTGAATATG 
TTTTTGGCTA TCATCAATGA TACTTACTCT GAAGTGAAAT CTGACTTGGC ACAGCAGAAA 
GCTGAAATGG AACTCTCAGA TCTTATCAGA AAGGGCTACC ATAAAGCTTT GGTCAAACTA 
AAACTGAAAA AAAATACCGT GGATGACATT TCAGAGAGTC TGCGGCAAGG AGGAGGCAAG 
TTAAACTTTG ACGAACTTCG ACAAGATCTC AAAGGGAAGG GCCATACTGA TGCAGAGATT 
GAGGCAATAT TCACAAAGTA CGACCAAGAT GGAGACCAAG AACTGACCGA ACATGAACAT 
CAGCAGATGA GAGACGACTT GGAGAAAGAG AGGGAGGACC TGGATTTGGA TCACAGTTCT 
TTACCACGTC CCATGAGCAG CCGAAGTTTC CCTCGAAGCC TGGATGACTC TGAGGAGGAT 
GACGATGAAG ATAGCGGACA TAGCTCCAGA AGGAGGGGAA GCATTTCTAG TGGCGTTTCT 
TACGAAGAGT TTCAAGTCCT GGTGAGACGA GTGGACCGGA TGGAGCATTC CATCGGCAGC 
ATAGTGTCCA AGATTGACGC CGTGATCGTG AAGCTAGAGA TTATGGAGCG AGCCAAACTG 
AAGAGGAGGG AGGTGCTGGG AAGGCTGTTG GATGGGGTGG CCGAGGATGA AAGGCTGGGT 
CGTGACAGTG AAATCCATAG GGAACAGATG GAACGGCTAG TACGTGAAGA GTTGGAACGC 
TGGGAATCCG ATGATGCAGC TTCCCAGATC AGTCATGGTT TAGGCACGCC AGTGGGACTA 
AATGGTCAAC CTCGCCCCAG AAGCTCCCGC CCATCTTCCT CCCAATCTAC AGAAGGCATG 
GAAGGTGCAG GTGGAAATGG GAGTTCTAAT GTCCACGTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530330.1
CDS	81..2762
Translation	MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLCEQRGLEIEMQRIRQAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRPGSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPLEGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTALLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV

Target ORF information:

RefSeq Version	XM_011532028.2
Organism	Homo sapiens(human)
Definition	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532028.2

ORF Insert Sequence:

ATGGTGAACT CCAGTCGCGT GCAGCCTCAG CAGCCCGGGG ACGCCAAGCG GCCGCCCGCG 
CCCCGCGCGC CGGACCCGGG CCGGCTGATG GCTGGCTGCG CGGCCGTGGG CGCCAGCCTC 
GCCGCCCCGG GCGGCCTCTG CGAGCAGCGG GGCCTGGAGA TCGAGATGCA GCGCATCCGG 
CAGGCGGCCG CGCGGGACCC CCCGGCCGGA GCCGCGGCCT CCCCTTCTCC TCCGCTCTCG 
TCGTGCTCCC GGCAGGCGTG GAGCCGCGAT AACCCCGGCT TCGAGGCCGA GGAGGAGGAG 
GAGGAGGTGG AAGGGGAAGA AGGCGGAATG GTGGTGGAGA TGGACGTAGA GTGGCGCCCG 
GGCAGCCGGA GGTCGGCCGC CTCCTCGGCC GTGAGCTCCG TGGGCGCGCG GAGCCGGGGG 
CTTGGGGGCT ACCACGGCGC GGGCCACCCG AGCGGGAGGC GGCGCCGGCG AGAGGACCAG 
GGCCCGCCGT GCCCCAGCCC AGTCGGCGGC GGGGACCCGC TGCATCGCCA CCTCCCCCTG 
GAAGGGCAGC CGCCCCGAGT GGCCTGGGCG GAGAGGCTGG TTCGCGGGCT GCGAGGTCTC 
TGGGGAACAA GACTCATGGA GGAAAGCAGC ACTAACCGAG AGAAATACCT TAAAAGTGTT 
TTACGGGAAC TGGTCACATA CCTCCTTTTT CTCATAGTCT TGTGCATCTT GACCTACGGC 
ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCGTTATT GGTTGAATTC CCAGCAACAG GTGGTGTGAT TCCATCTTGG 
CAATTTCAGC CTTTAAAGCT GATCCGATAT GTCACAACTT TTGATTTCTT CCTGGCAGCC 
TGTGAGATTA TCTTTTGTTT CTTTATCTTT TACTATGTGG TGGAAGAGAT ATTGGAAATT 
CGCATTCACA AACTACACTA TTTCAGGAGT TTCTGGAATT GTCTGGATGT TGTGATCGTT 
GTGCTGTCAG TGGTAGCTAT AGGAATTAAC ATATACAGAA CATCAAATGT GGAGGTGCTA 
CTACAGTTTC TGGAAGATCA AAATACTTTC CCCAACTTTG AGCATCTGGC ATATTGGCAG 
ATACAGTTCA ACAATATAGC TGCTGTCACA GTATTTTTTG TCTGGATTAA GCTCTTCAAA 
TTCATCAATT TTAACAGGAC CATGAGCCAG CTCTCGACAA CCATGTCTCG ATGTGCCAAA 
GACCTGTTTG GCTTTGCTAT TATGTTCTTC ATTATTTTCC TAGCGTATGC TCAGTTGGCA 
TACCTTGTCT TTGGCACTCA GGTCGATGAC TTCAGTACTT TCCAAGAGTG TATCTTCACT 
CAATTCCGTA TCATTTTGGG CGATATCAAC TTTGCAGAGA TTGAGGAAGC TAATCGAGTT 
TTGGGACCAA TTTATTTCAC TACATTTGTG TTCTTTATGT TCTTCATTCT TTTGAATATG 
TTTTTGGCTA TCATCAATGA TACTTACTCT GAAGTGAAAT CTGACTTGGC ACAGCAGAAA 
GCTGAAATGG AACTCTCAGA TCTTATCAGA AAGGGCTACC ATAAAGCTTT GGTCAAACTA 
AAACTGAAAA AAAATACCGT GGATGACATT TCAGAGAGTC TGCGGCAAGG AGGAGGCAAG 
TTAAACTTTG ACGAACTTCG ACAAGATCTC AAAGGGAAGG GCCATACTGA TGCAGAGATT 
GAGGCAATAT TCACAAAGTA CGACCAAGAT GGAGACCAAG AACTGACCGA ACATGAACAT 
CAGCAGATGA GAGACGACTT GGAGAAAGAG AGGGAGGACC TGGATTTGGA TCACAGTTCT 
TTACCACGTC CCATGAGCAG CCGAAGTTTC CCTCGAAGCC TGGATGACTC TGAGGAGGAT 
GACGATGAAG ATAGCGGACA TAGCTCCAGA AGGAGGGGAA GCATTTCTAG TGGCGTTTCT 
TACGAAGAGT TTCAAGTCCT GGTGAGACGA GTGGACCGGA TGGAGCATTC CATCGGCAGC 
ATAGTGTCCA AGATTGACGC CGTGATCGTG AAGCTAGAGA TTATGGAGCG AGCCAAACTG 
AAGAGGAGGG AGGTGCTGGG AAGGCTGTTG GATGGGGTGG CCGAGGATGA AAGGCTGGGT 
CGTGACAGTG AAATCCATAG GGAACAGATG GAACGGCTAG TACGTGAAGA GTTGGAACGC 
TGGGAATCCG ATGATGCAGC TTCCCAGATC AGTCATGGTT TAGGCACGCC AGTGGGACTA 
AATGGTCAAC CTCGCCCCAG AAGCTCCCGC CCATCTTCCT CCCAATCTAC AGAAGGCATG 
GAAGGTGCAG GTGGAAATGG GAGTTCTAAT GTCCACGTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKD2 ( XM_011532029.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530331.1 Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu59728
Clone ID Related Accession (Same CDS sequence)	XM_011532029.1
Accession Version	XM_011532029.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	polycystin-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530331.1
CDS	98..2284
Translation	MMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV

Target ORF information:

RefSeq Version	XM_011532029.1
Organism	Homo sapiens(human)
Definition	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532029.1

ORF Insert Sequence:

ATGATGAGCT CCAATGTGTA CTACTACACC CGGATGATGT CACAGCTCTT CCTAGACACC 
CCCGTGTCCA AAACGGAGAA AACTAACTTT AAAACTCTGT CTTCCATGGA AGACTTCTGG 
AAGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKD2 ( XM_011532030.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530332.1 Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X3, mRNA.

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CloneID	OHu59729
Clone ID Related Accession (Same CDS sequence)	XM_011532030.2
Accession Version	XM_011532030.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2067bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	polycystin-2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532030.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530332.1
CDS	259..2325
Translation	MFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV

Target ORF information:

RefSeq Version	XM_011532030.2
Organism	Homo sapiens(human)
Definition	Homo sapiens polycystin 2, transient receptor potential cation channel (PKD2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532030.2

ORF Insert Sequence:

ATGTTCACAG AAGGCTCCTT ATTGGATGGG CTGTACTGGA AGATGCAGCC CAGCAACCAG 
ACTGAAGCTG ACAACCGAAG TTTCATCTTC TATGAGAACC TGCTGTTAGG GGTTCCACGA 
ATACGGCAAC TCCGAGTCAG AAATGGATCC TGCTCTATCC CCCAGGACTT GAGAGATGAA 
ATTAAAGAGT GCTATGATGT CTACTCTGTC AGTAGTGAAG ATAGGGCTCC CTTTGGGCCC 
CGAAATGGAA CCGCTTGGAT CTACACAAGT GAAAAAGACT TGAATGGTAG TAGCCACTGG 
GGAATCATTG CAACTTATAG TGGAGCTGGC TATTATCTGG ATTTGTCAAG AACAAGAGAG 
GAAACAGCTG CACAAGTTGC TAGCCTCAAG AAAAATGTCT GGCTGGACCG AGGAACCAGG 
GCAACTTTTA TTGACTTCTC AGTGTACAAC GCCAACATTA ACCTGTTCTG TGTGGTCAGG 
TTATTGGTTG AATTCCCAGC AACAGGTGGT GTGATTCCAT CTTGGCAATT TCAGCCTTTA 
AAGCTGATCC GATATGTCAC AACTTTTGAT TTCTTCCTGG CAGCCTGTGA GATTATCTTT 
TGTTTCTTTA TCTTTTACTA TGTGGTGGAA GAGATATTGG AAATTCGCAT TCACAAACTA 
CACTATTTCA GGAGTTTCTG GAATTGTCTG GATGTTGTGA TCGTTGTGCT GTCAGTGGTA 
GCTATAGGAA TTAACATATA CAGAACATCA AATGTGGAGG TGCTACTACA GTTTCTGGAA 
GATCAAAATA CTTTCCCCAA CTTTGAGCAT CTGGCATATT GGCAGATACA GTTCAACAAT 
ATAGCTGCTG TCACAGTATT TTTTGTCTGG ATTAAGCTCT TCAAATTCAT CAATTTTAAC 
AGGACCATGA GCCAGCTCTC GACAACCATG TCTCGATGTG CCAAAGACCT GTTTGGCTTT 
GCTATTATGT TCTTCATTAT TTTCCTAGCG TATGCTCAGT TGGCATACCT TGTCTTTGGC 
ACTCAGGTCG ATGACTTCAG TACTTTCCAA GAGTGTATCT TCACTCAATT CCGTATCATT 
TTGGGCGATA TCAACTTTGC AGAGATTGAG GAAGCTAATC GAGTTTTGGG ACCAATTTAT 
TTCACTACAT TTGTGTTCTT TATGTTCTTC ATTCTTTTGA ATATGTTTTT GGCTATCATC 
AATGATACTT ACTCTGAAGT GAAATCTGAC TTGGCACAGC AGAAAGCTGA AATGGAACTC 
TCAGATCTTA TCAGAAAGGG CTACCATAAA GCTTTGGTCA AACTAAAACT GAAAAAAAAT 
ACCGTGGATG ACATTTCAGA GAGTCTGCGG CAAGGAGGAG GCAAGTTAAA CTTTGACGAA 
CTTCGACAAG ATCTCAAAGG GAAGGGCCAT ACTGATGCAG AGATTGAGGC AATATTCACA 
AAGTACGACC AAGATGGAGA CCAAGAACTG ACCGAACATG AACATCAGCA GATGAGAGAC 
GACTTGGAGA AAGAGAGGGA GGACCTGGAT TTGGATCACA GTTCTTTACC ACGTCCCATG 
AGCAGCCGAA GTTTCCCTCG AAGCCTGGAT GACTCTGAGG AGGATGACGA TGAAGATAGC 
GGACATAGCT CCAGAAGGAG GGGAAGCATT TCTAGTGGCG TTTCTTACGA AGAGTTTCAA 
GTCCTGGTGA GACGAGTGGA CCGGATGGAG CATTCCATCG GCAGCATAGT GTCCAAGATT 
GACGCCGTGA TCGTGAAGCT AGAGATTATG GAGCGAGCCA AACTGAAGAG GAGGGAGGTG 
CTGGGAAGGC TGTTGGATGG GGTGGCCGAG GATGAAAGGC TGGGTCGTGA CAGTGAAATC 
CATAGGGAAC AGATGGAACG GCTAGTACGT GAAGAGTTGG AACGCTGGGA ATCCGATGAT 
GCAGCTTCCC AGATCAGTCA TGGTTTAGGC ACGCCAGTGG GACTAAATGG TCAACCTCGC 
CCCAGAAGCT CCCGCCCATC TTCCTCCCAA TCTACAGAAG GCATGGAAGG TGCAGGTGGA 
AATGGGAGTT CTAATGTCCA CGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A role for polycystin-1 and polycystin-2 in neural progenitor cell differentiation.
Cellular and molecular life sciences : CMLS76(14)2851-2869(2019 Jul)
Winokurow N,Schumacher S

Identification of PKD1 and PKD2 gene variants in a cohort of 125 Asian Indian patients of ADPKD.
Journal of human genetics64(5)409-419(2019 May)
Pandita S,Ramachandran V,Balakrishnan P,Rolfs A,Brandau O,Eichler S,Bhalla AK,Khullar D,Amitabh V,Ramanarayanan S,Kher V,Verma J,Kohli S,Saxena R,Verma IC

Polycystins and Mechanotransduction in Human Disease.
International journal of molecular sciences20(9)(2019 May)
Gargalionis AN,Basdra EK,Papavassiliou AG

The Polycystin Complex Reveals Its Complexity.
Biochemistry57(51)6917-6918(2018 12)
Padovano V,Caplan MJ

MicroRNA-106b-5p regulates cisplatin chemosensitivity by targeting polycystic kidney disease-2 in non-small-cell lung cancer.
Anti-cancer drugs28(8)852-860(2017 09)
Yu S,Qin X,Chen T,Zhou L,Xu X,Feng J

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PKD2 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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