RAB8B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAB8B
Entrez Gene ID	51762
Full Name	RAB8B, member RAS oncogene family
General protein information	Preferred Names RAB8B, member RAS oncogene family Names ras-related protein Rab-8B RAB-8b protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q22.2
Summary	RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010].
Disorder MIM:	613532

mRNA and Protein(s)

mRNA	Protein	Name
NM_016530.3	NP_057614.1	ras-related protein Rab-8B
NM_016530.2	NP_057614.1	ras-related protein Rab-8B
XM_017022312.1	XP_016877801.1	ras-related protein Rab-8B isoform X1
XM_011521669.3	XP_011519971.1	ras-related protein Rab-8B isoform X2
XM_011521669.2	XP_011519971.1	ras-related protein Rab-8B isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RAB8B	XP_510465.4
Mus musculus (house mouse)	Rab8b	NP_775589.1
Homo sapiens (human)	RAB8B	NP_057614.1
Canis lupus familiaris (dog)	RAB8B	XP_005638551.1
Rattus norvegicus (Norway rat)	Rab8b	NP_695229.1
Gallus gallus (chicken)	RAB8B	XP_004943799.1
Xenopus tropicalis (tropical clawed frog)	rab8b	NP_001090677.1
Danio rerio (zebrafish)	rab8b	NP_001092729.1
Oryza sativa (rice)	Os07g0195100	NP_001059115.1
Macaca mulatta (Rhesus monkey)	RAB8B	XP_002804851.1
Bos taurus (cattle)	RAB8B	NP_001069785.1

Gene Ontology
Bibliography

Related articles in PubMed

The rs1986112 Variant is Associated with Increased RAB8B Gene Expression in Schizophrenic Patients.
Johari AH, Nejad FR, Mansoori N, Vafaei F, Salehi S, Alehabib E, Alinaghi S, Chapi M, Jamali F, Darvish H, Ghaedi H
Clinical laboratory65(4)(2019 Apr)

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.
Lai YC, Kondapalli C, Lehneck R, Procter JB, Dill BD, Woodroof HI, Gourlay R, Peggie M, Macartney TJ, Corti O, Corvol JC, Campbell DG, Itzen A, Trost M, Muqit MM
The EMBO journal34(22)2840-61(2015 Nov)

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.
St Pourcain B, Skuse DH, Mandy WP, Wang K, Hakonarson H, Timpson NJ, Evans DM, Kemp JP, Ring SM, McArdle WL, Golding J, Smith GD
Molecular autism5(1)18(2014 Feb)

Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.
Seto S, Tsujimura K, Koide Y
Traffic (Copenhagen, Denmark)12(4)407-20(2011 Apr)

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
Yoshimura S, Gerondopoulos A, Linford A, Rigden DJ, Barr FA
The Journal of cell biology191(2)367-81(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RAB8B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAB8B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02309	NM_016530.3 Latest version!	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu48373	XM_017022312.1 Latest version!	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu68159	XM_011521669.3 Latest version!	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu02309	NM_016530.2	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu68159	XM_011521669.2	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAB8B ( NM_016530.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057614.1 Homo sapiens RAB8B, member RAS oncogene family (RAB8B), mRNA.

Price & Availability↑

CloneID	OHu02309
Clone ID Related Accession (Same CDS sequence)	NM_016530.3 , NM_016530.2
Accession Version	NM_016530.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	ras-related protein Rab-8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG721755.1, AB038995.1 and AC016207.9. On Nov 23, 2018 this sequence version replaced NM_016530.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.183400.1, SRR1660803.106208.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000321437.9/ ENSP00000312734.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGGGCA TTATGCTGGT CTATGACATC ACAAATGAAA AATCCTTTGA CAATATTAAA 
AATTGGATCA GAAACATTGA AGAGCATGCC TCTTCCGATG TCGAAAGAAT GATCCTGGGT 
AACAAATGTG ATATGAATGA CAAAAGACAA GTGTCAAAAG AAAGAGGGGA GAAGCTAGCA 
ATTGACTATG GGATTAAATT CTTGGAGACA AGCGCAAAAT CCAGTGCAAA TGTAGAAGAG 
GCATTTTTTA CACTTGCACG AGATATAATG ACAAAACTCA ACAGAAAAAT GAATGACAGC 
AATTCAGCAG GAGCAGGTGG ACCAGTGAAA ATAACAGAAA ACCGATCAAA GAAGACCAGT 
TTCTTTCGTT GCTCGCTACT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057614.1
CDS	20..643
Translation	MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITENRSKKTSFFRCSLL

Target ORF information:

RefSeq Version	NM_016530.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016530.3

ORF Insert Sequence:

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGGGCA TTATGCTGGT CTATGACATC ACAAATGAAA AATCCTTTGA CAATATTAAA 
AATTGGATCA GAAACATTGA AGAGCATGCC TCTTCCGATG TCGAAAGAAT GATCCTGGGT 
AACAAATGTG ATATGAATGA CAAAAGACAA GTGTCAAAAG AAAGAGGGGA GAAGCTAGCA 
ATTGACTATG GGATTAAATT CTTGGAGACA AGCGCAAAAT CCAGTGCAAA TGTAGAAGAG 
GCATTTTTTA CACTTGCACG AGATATAATG ACAAAACTCA ACAGAAAAAT GAATGACAGC 
AATTCAGCAG GAGCAGGTGG ACCAGTGAAA ATAACAGAAA ACCGATCAAA GAAGACCAGT 
TTCTTTCGTT GCTCGCTACT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAB8B ( NM_016530.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_057614.1 Homo sapiens RAB8B, member RAS oncogene family (RAB8B), mRNA.

Price & Availability↑

CloneID	OHu02309
Clone ID Related Accession (Same CDS sequence)	NM_016530.3 , NM_016530.2
Accession Version	NM_016530.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514217600000
Organism	Homo sapiens(human)
Product	ras-related protein Rab-8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG721755.1, AB038995.1 and AC016207.9. On Apr 22, 2005 this sequence version replaced NM_016530.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.183400.1, SRR1660807.106654.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGGGCA TTATGCTGGT CTATGACATC ACAAATGAAA AATCCTTTGA CAATATTAAA 
AATTGGATCA GAAACATTGA AGAGCATGCC TCTTCCGATG TCGAAAGAAT GATCCTGGGT 
AACAAATGTG ATATGAATGA CAAAAGACAA GTGTCAAAAG AAAGAGGGGA GAAGCTAGCA 
ATTGACTATG GGATTAAATT CTTGGAGACA AGCGCAAAAT CCAGTGCAAA TGTAGAAGAG 
GCATTTTTTA CACTTGCACG AGATATAATG ACAAAACTCA ACAGAAAAAT GAATGACAGC 
AATTCAGCAG GAGCAGGTGG ACCAGTGAAA ATAACAGAAA ACCGATCAAA GAAGACCAGT 
TTCTTTCGTT GCTCGCTACT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057614.1
CDS	97..720
Translation	MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITENRSKKTSFFRCSLL

Target ORF information:

RefSeq Version	NM_016530.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016530.2

ORF Insert Sequence:

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGGGCA TTATGCTGGT CTATGACATC ACAAATGAAA AATCCTTTGA CAATATTAAA 
AATTGGATCA GAAACATTGA AGAGCATGCC TCTTCCGATG TCGAAAGAAT GATCCTGGGT 
AACAAATGTG ATATGAATGA CAAAAGACAA GTGTCAAAAG AAAGAGGGGA GAAGCTAGCA 
ATTGACTATG GGATTAAATT CTTGGAGACA AGCGCAAAAT CCAGTGCAAA TGTAGAAGAG 
GCATTTTTTA CACTTGCACG AGATATAATG ACAAAACTCA ACAGAAAAAT GAATGACAGC 
AATTCAGCAG GAGCAGGTGG ACCAGTGAAA ATAACAGAAA ACCGATCAAA GAAGACCAGT 
TTCTTTCGTT GCTCGCTACT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAB8B ( XM_017022312.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877801.1 Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu48373
Clone ID Related Accession (Same CDS sequence)	XM_017022312.1
Accession Version	XM_017022312.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	ras-related protein Rab-8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCATTA TGCTGGTCTA TGACATCACA AATGAAAAAT CCTTTGACAA TATTAAAAAT 
TGGATCAGAA ACATTGAAGA GCATGCCTCT TCCGATGTCG AAAGAATGAT CCTGGGTAAC 
AAATGTGATA TGAATGACAA AAGACAAGTG TCAAAAGAAA GAGGGGAGAA GCTAGCAATT 
GACTATGGGA TTAAATTCTT GGAGACAAGC GCAAAATCCA GTGCAAATGT AGAAGAGGCA 
TTTTTTACAC TTGCACGAGA TATAATGACA AAACTCAACA GAAAAATGAA TGACAGCAAT 
TCAGCAGGAG CAGGTGGACC AGTGAAAATA ACAGAAAACC GATCAAAGAA GACCAGTTTC 
TTTCGTTGCT CGCTACTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877801.1
CDS	395..775
Translation	MGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITENRSKKTSFFRCSLL

Target ORF information:

RefSeq Version	XM_017022312.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022312.1

ORF Insert Sequence:

ATGGGCATTA TGCTGGTCTA TGACATCACA AATGAAAAAT CCTTTGACAA TATTAAAAAT 
TGGATCAGAA ACATTGAAGA GCATGCCTCT TCCGATGTCG AAAGAATGAT CCTGGGTAAC 
AAATGTGATA TGAATGACAA AAGACAAGTG TCAAAAGAAA GAGGGGAGAA GCTAGCAATT 
GACTATGGGA TTAAATTCTT GGAGACAAGC GCAAAATCCA GTGCAAATGT AGAAGAGGCA 
TTTTTTACAC TTGCACGAGA TATAATGACA AAACTCAACA GAAAAATGAA TGACAGCAAT 
TCAGCAGGAG CAGGTGGACC AGTGAAAATA ACAGAAAACC GATCAAAGAA GACCAGTTTC 
TTTCGTTGCT CGCTACTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAB8B ( XM_011521669.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519971.1 Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu68159
Clone ID Related Accession (Same CDS sequence)	XM_011521669.3 , XM_011521669.2
Accession Version	XM_011521669.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	ras-related protein Rab-8B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011521669.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGCCCT GCCACCATTA TCTCTTACCT CACCACCTCC ACAACATCCA CTGCTGTGGC 
TCATCTCCCT GTCATCCCCC TGACCACCAT TCTGCCAGCT GGCCGGAAAG AATCTGGAAG 
GAATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519971.1
CDS	90..458
Translation	MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMPCHHYLLPHHLHNIHCCGSSPCHPPDHHSASWPERIWKEF

Target ORF information:

RefSeq Version	XM_011521669.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521669.3

ORF Insert Sequence:

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGCCCT GCCACCATTA TCTCTTACCT CACCACCTCC ACAACATCCA CTGCTGTGGC 
TCATCTCCCT GTCATCCCCC TGACCACCAT TCTGCCAGCT GGCCGGAAAG AATCTGGAAG 
GAATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAB8B ( XM_011521669.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519971.1 Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu68159
Clone ID Related Accession (Same CDS sequence)	XM_011521669.3 , XM_011521669.2
Accession Version	XM_011521669.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	ras-related protein Rab-8B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011521669.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGCCCT GCCACCATTA TCTCTTACCT CACCACCTCC ACAACATCCA CTGCTGTGGC 
TCATCTCCCT GTCATCCCCC TGACCACCAT TCTGCCAGCT GGCCGGAAAG AATCTGGAAG 
GAATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519971.1
CDS	90..458
Translation	MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMPCHHYLLPHHLHNIHCCGSSPCHPPDHHSASWPERIWKEF

Target ORF information:

RefSeq Version	XM_011521669.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB8B, member RAS oncogene family (RAB8B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521669.2

ORF Insert Sequence:

ATGGCGAAGA CGTACGATTA TCTCTTCAAG CTCCTGCTGA TCGGCGACTC GGGGGTAGGC 
AAGACCTGCC TCCTGTTCCG CTTCTCAGAG GACGCCTTCA ACACCACCTT CATCTCCACC 
ATCGGAATTG ATTTTAAAAT TAGAACGATA GAACTAGATG GAAAGAAAAT TAAGCTTCAG 
ATATGGGACA CAGCGGGTCA GGAAAGATTC CGAACAATCA CGACAGCGTA CTACAGAGGA 
GCCATGCCCT GCCACCATTA TCTCTTACCT CACCACCTCC ACAACATCCA CTGCTGTGGC 
TCATCTCCCT GTCATCCCCC TGACCACCAT TCTGCCAGCT GGCCGGAAAG AATCTGGAAG 
GAATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The rs1986112 Variant is Associated with Increased RAB8B Gene Expression in Schizophrenic Patients.
Clinical laboratory65(4)(2019 Apr)
Johari AH,Nejad FR,Mansoori N,Vafaei F,Salehi S,Alehabib E,Alinaghi S,Chapi M,Jamali F,Darvish H,Ghaedi H

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.
The EMBO journal34(22)2840-61(2015 Nov)
Lai YC,Kondapalli C,Lehneck R,Procter JB,Dill BD,Woodroof HI,Gourlay R,Peggie M,Macartney TJ,Corti O,Corvol JC,Campbell DG,Itzen A,Trost M,Muqit MM

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.
Molecular autism5(1)18(2014 Feb)
St Pourcain B,Skuse DH,Mandy WP,Wang K,Hakonarson H,Timpson NJ,Evans DM,Kemp JP,Ring SM,McArdle WL,Golding J,Smith GD

Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.
Traffic (Copenhagen, Denmark)12(4)407-20(2011 Apr)
Seto S,Tsujimura K,Koide Y

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
The Journal of cell biology191(2)367-81(2010 Oct)
Yoshimura S,Gerondopoulos A,Linford A,Rigden DJ,Barr FA

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