NDUFA3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NDUFA3
Entrez Gene ID	4696
Full Name	NADH:ubiquinone oxidoreductase subunit A3
Synonyms	B9,CI-B9
General protein information	Preferred Names NADH:ubiquinone oxidoreductase subunit A3 Names NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa NADH-ubiquinone oxidoreductase B9 subunit complex I B9 subunit complex I-B9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.42
Disorder MIM:	603832

mRNA and Protein(s)

mRNA	Protein	Name
XM_017026833.1	XP_016882322.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1
NM_004542.3	NP_004533.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
NM_004542.4	NP_004533.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LOC710937	XP_001098699.1
Danio rerio (zebrafish)	zgc:100908	NP_001003516.2
Pan troglodytes (chimpanzee)	NDUFA3	NP_001238904.1
Bos taurus (cattle)	NDUFA3	NP_788832.1
Mus musculus (house mouse)	Ndufa3	NP_079624.1
Homo sapiens (human)	NDUFA3	NP_004533.1
Rattus norvegicus (Norway rat)	Ndufa3	XP_001076462.2
Rattus norvegicus (Norway rat)	LOC684509	XP_003749429.1
Xenopus tropicalis (tropical clawed frog)	ndufa3	NP_001017047.1

Gene Ontology
Bibliography

Related articles in PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT
Nature538(7623)123-126(2016 Oct)

Supernumerary subunits NDUFA3, NDUFA5 and NDUFA12 are required for the formation of the extramembrane arm of human mitochondrial complex I.
Rak M, Rustin P
FEBS letters588(9)1832-8(2014 May)

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Casabonne D, Reina O, Benavente Y, Becker N, Maynadié M, Foretová L, Cocco P, González-Neira A, Nieters A, Boffetta P, Middeldorp JM, de Sanjose S
Haematologica96(2)323-7(2011 Feb)

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
Zhao X, León IR, Bak S, Mogensen M, Wrzesinski K, Højlund K, Jensen ON
Molecular & cellular proteomics : MCP10(1)M110.000299(2011 Jan)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NDUFA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NDUFA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26234	NM_004542.4 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu26234	XM_017026833.1 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu26234	NM_004542.3	Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NDUFA3 ( NM_004542.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004533.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), mRNA.

Price & Availability↑

CloneID	OHu26234
Clone ID Related Accession (Same CDS sequence)	XM_017026833.1 , NM_004542.3 , NM_004542.4
Accession Version	NM_004542.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550505600000
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC061644.1. On Jan 22, 2009 this sequence version replaced NM_004542.2. ##Evidence-Data-START## Transcript exon combination :: BC061644.1, BU851920.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGCGA GAGTCGGCGC CTTCCTCAAG AATGCCTGGG ACAAGGAGCC AGTGCTGGTC 
GTGTCCTTCG TCGTCGGGGG CCTCGCTGTA ATTCTGCCCC CATTGAGCCC CTACTTCAAG 
TACTCCGTCA TGATCAACAA GGCCACGCCC TACAACTACC CAGTGCCCGT CCGTGATGAT 
GGGAACATGC CCGACGTGCC CAGCCACCCC CAGGACCCTC AGGGCCCCAG CCTGGAGTGG 
CTGAAGAAAC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004533.1
CDS	28..282
Translation	MAARVGAFLKNAWDKEPVLVVSFVVGGLAVILPPLSPYFKYSVMINKATPYNYPVPVRDDGNMPDVPSHPQDPQGPSLEWLKKL

Target ORF information:

RefSeq Version	NM_004542.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004542.3

ORF Insert Sequence:

ATGGCTGCGA GAGTCGGCGC CTTCCTCAAG AATGCCTGGG ACAAGGAGCC AGTGCTGGTC 
GTGTCCTTCG TCGTCGGGGG CCTCGCTGTA ATTCTGCCCC CATTGAGCCC CTACTTCAAG 
TACTCCGTCA TGATCAACAA GGCCACGCCC TACAACTACC CAGTGCCCGT CCGTGATGAT 
GGGAACATGC CCGACGTGCC CAGCCACCCC CAGGACCCTC AGGGCCCCAG CCTGGAGTGG 
CTGAAGAAAC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFA3 ( NM_004542.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004533.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), mRNA.

Price & Availability↑

CloneID	OHu26234
Clone ID Related Accession (Same CDS sequence)	XM_017026833.1 , NM_004542.3 , NM_004542.4
Accession Version	NM_004542.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC061644.1 and AC245052.3. On May 17, 2019 this sequence version replaced NM_004542.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.315261.1, EL582436.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000485876.6/ ENSP00000418438.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGCTGCGA GAGTCGGCGC CTTCCTCAAG AATGCCTGGG ACAAGGAGCC AGTGCTGGTC 
GTGTCCTTCG TCGTCGGGGG CCTCGCTGTA ATTCTGCCCC CATTGAGCCC CTACTTCAAG 
TACTCCGTCA TGATCAACAA GGCCACGCCC TACAACTACC CAGTGCCCGT CCGTGATGAT 
GGGAACATGC CCGACGTGCC CAGCCACCCC CAGGACCCTC AGGGCCCCAG CCTGGAGTGG 
CTGAAGAAAC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004533.1
CDS	25..279
Translation	MAARVGAFLKNAWDKEPVLVVSFVVGGLAVILPPLSPYFKYSVMINKATPYNYPVPVRDDGNMPDVPSHPQDPQGPSLEWLKKL

Target ORF information:

RefSeq Version	NM_004542.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004542.4

ORF Insert Sequence:

ATGGCTGCGA GAGTCGGCGC CTTCCTCAAG AATGCCTGGG ACAAGGAGCC AGTGCTGGTC 
GTGTCCTTCG TCGTCGGGGG CCTCGCTGTA ATTCTGCCCC CATTGAGCCC CTACTTCAAG 
TACTCCGTCA TGATCAACAA GGCCACGCCC TACAACTACC CAGTGCCCGT CCGTGATGAT 
GGGAACATGC CCGACGTGCC CAGCCACCCC CAGGACCCTC AGGGCCCCAG CCTGGAGTGG 
CTGAAGAAAC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFA3 ( XM_017026833.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882322.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu26234
Clone ID Related Accession (Same CDS sequence)	XM_017026833.1 , NM_004542.3 , NM_004542.4
Accession Version	XM_017026833.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCGA GAGTCGGCGC CTTCCTCAAG AATGCCTGGG ACAAGGAGCC AGTGCTGGTC 
GTGTCCTTCG TCGTCGGGGG CCTCGCTGTA ATTCTGCCCC CATTGAGCCC CTACTTCAAG 
TACTCCGTCA TGATCAACAA GGCCACGCCC TACAACTACC CAGTGCCCGT CCGTGATGAT 
GGGAACATGC CCGACGTGCC CAGCCACCCC CAGGACCCTC AGGGCCCCAG CCTGGAGTGG 
CTGAAGAAAC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882322.1
CDS	445..699
Translation	MAARVGAFLKNAWDKEPVLVVSFVVGGLAVILPPLSPYFKYSVMINKATPYNYPVPVRDDGNMPDVPSHPQDPQGPSLEWLKKL

Target ORF information:

RefSeq Version	XM_017026833.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A3 (NDUFA3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026833.1

ORF Insert Sequence:

ATGGCTGCGA GAGTCGGCGC CTTCCTCAAG AATGCCTGGG ACAAGGAGCC AGTGCTGGTC 
GTGTCCTTCG TCGTCGGGGG CCTCGCTGTA ATTCTGCCCC CATTGAGCCC CTACTTCAAG 
TACTCCGTCA TGATCAACAA GGCCACGCCC TACAACTACC CAGTGCCCGT CCGTGATGAT 
GGGAACATGC CCGACGTGCC CAGCCACCCC CAGGACCCTC AGGGCCCCAG CCTGGAGTGG 
CTGAAGAAAC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Nature538(7623)123-126(2016 Oct)
Stroud DA,Surgenor EE,Formosa LE,Reljic B,Frazier AE,Dibley MG,Osellame LD,Stait T,Beilharz TH,Thorburn DR,Salim A,Ryan MT

Supernumerary subunits NDUFA3, NDUFA5 and NDUFA12 are required for the formation of the extramembrane arm of human mitochondrial complex I.
FEBS letters588(9)1832-8(2014 May)
Rak M,Rustin P

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Haematologica96(2)323-7(2011 Feb)
Casabonne D,Reina O,Benavente Y,Becker N,Maynadié M,Foretová L,Cocco P,González-Neira A,Nieters A,Boffetta P,Middeldorp JM,de Sanjose S

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
Molecular & cellular proteomics : MCP10(1)M110.000299(2011 Jan)
Zhao X,León IR,Bak S,Mogensen M,Wrzesinski K,Højlund K,Jensen ON

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

NDUFA3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM