MYOC cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MYOC
Entrez Gene ID	4653
Full Name	myocilin
Synonyms	GLC1A,GPOA,JOAG,JOAG1,TIGR
General protein information	Preferred Names myocilin Names myocilin juvenile-onset open-angle glaucoma 1 mutated trabecular meshwork-induced glucocorticoid response protein myocilin 55 kDa subunit myocilin trabecular meshwork inducible glucocorticoid response protein trabecular meshwork inducible glucocorticoid response protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q24.3
Summary	MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008].
Disorder MIM:	601652
Disorder Html:	Glaucoma 1A, primary open angle, 137750 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000261.2	NP_000252.1	myocilin precursor
NM_000261.1	NP_000252.1	myocilin precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	MYOC	NP_000252.1
Macaca mulatta (Rhesus monkey)	MYOC	XP_001099905.1
Danio rerio (zebrafish)	myoc	NP_001015062.1
Mus musculus (house mouse)	Myoc	NP_034995.3
Gallus gallus (chicken)	MYOC	XP_422235.4
Xenopus tropicalis (tropical clawed frog)	myoc	XP_002934195.2
Pan troglodytes (chimpanzee)	MYOC	XP_513995.2
Canis lupus familiaris (dog)	MYOC	NP_001041495.2
Bos taurus (cattle)	MYOC	NP_776543.2
Rattus norvegicus (Norway rat)	Myoc	NP_110492.1

Gene Ontology
Bibliography

Related articles in PubMed

[Analysis of MYOC gene variants among sporadic patients with primary open-angle glaucoma].
Zhang X, Zhang D, Huang L, Hao F, Lin Y, Gong B, Yang Z
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics36(7)662-665(2019 Jul)

Occurrence of MYOC and CYP1B1 variants in juvenile open angle glaucoma Brazilian patients.
Svidnicki PV, Braghini CA, Costa VP, Schimiti RB, de Vasconcellos JPC, de Melo MB
Ophthalmic genetics39(6)717-724(2018 12)

Estimating the age of the p.Cys433Arg variant in the MYOC gene in patients with primary open-angle glaucoma.
Marques AM, Ananina G, Costa VP, de Vasconcellos JPC, de Melo MB
PloS one13(11)e0207409(2018)

Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle.
Lynch JM, Dolman AJ, Guo C, Dolan K, Xiang C, Reda S, Li B, Prasanna G
PloS one13(11)e0206801(2018)

Identification of myocilin as a blood plasma protein and analysis of its role in leukocyte adhesion to endothelial cell monolayers.
Aroca-Aguilar JD, Fernández-Navarro A, Ontañón J, Coca-Prados M, Escribano J
PloS one13(12)e0209364(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MYOC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYOC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24937	NM_000261.2 Latest version!	Homo sapiens myocilin (MYOC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
View Old Accession Versions >>
OHu24937	NM_000261.1	Homo sapiens myocilin (MYOC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MYOC ( NM_000261.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_000252.1 Homo sapiens myocilin (MYOC), mRNA.

Price & Availability↑

CloneID	OHu24937
Clone ID Related Accession (Same CDS sequence)	NM_000261.2 , NM_000261.1
Accession Version	NM_000261.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	myocilin precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z98750.1 and AF001620.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000261.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.323867.1, U85257.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153980, SAMEA2154125 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000037502.11/ ENSP00000037502.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGTTCT TCTGTGCACG TTGCTGCAGC TTTGGGCCTG AGATGCCAGC TGTCCAGCTG 
CTGCTTCTGG CCTGCCTGGT GTGGGATGTG GGGGCCAGGA CAGCTCAGCT CAGGAAGGCC 
AATGACCAGA GTGGCCGATG CCAGTATACC TTCAGTGTGG CCAGTCCCAA TGAATCCAGC 
TGCCCAGAGC AGAGCCAGGC CATGTCAGTC ATCCATAACT TACAGAGAGA CAGCAGCACC 
CAACGCTTAG ACCTGGAGGC CACCAAAGCT CGACTCAGCT CCCTGGAGAG CCTCCTCCAC 
CAATTGACCT TGGACCAGGC TGCCAGGCCC CAGGAGACCC AGGAGGGGCT GCAGAGGGAG 
CTGGGCACCC TGAGGCGGGA GCGGGACCAG CTGGAAACCC AAACCAGAGA GTTGGAGACT 
GCCTACAGCA ACCTCCTCCG AGACAAGTCA GTTCTGGAGG AAGAGAAGAA GCGACTAAGG 
CAAGAAAATG AGAATCTGGC CAGGAGGTTG GAAAGCAGCA GCCAGGAGGT AGCAAGGCTG 
AGAAGGGGCC AGTGTCCCCA GACCCGAGAC ACTGCTCGGG CTGTGCCACC AGGCTCCAGA 
GAAGTTTCTA CGTGGAATTT GGACACTTTG GCCTTCCAGG AACTGAAGTC CGAGCTAACT 
GAAGTTCCTG CTTCCCGAAT TTTGAAGGAG AGCCCATCTG GCTATCTCAG GAGTGGAGAG 
GGAGACACCG GATGTGGAGA ACTAGTTTGG GTAGGAGAGC CTCTCACGCT GAGAACAGCA 
GAAACAATTA CTGGCAAGTA TGGTGTGTGG ATGCGAGACC CCAAGCCCAC CTACCCCTAC 
ACCCAGGAGA CCACGTGGAG AATCGACACA GTTGGCACGG ATGTCCGCCA GGTTTTTGAG 
TATGACCTCA TCAGCCAGTT TATGCAGGGC TACCCTTCTA AGGTTCACAT ACTGCCTAGG 
CCACTGGAAA GCACGGGTGC TGTGGTGTAC TCGGGGAGCC TCTATTTCCA GGGCGCTGAG 
TCCAGAACTG TCATAAGATA TGAGCTGAAT ACCGAGACAG TGAAGGCTGA GAAGGAAATC 
CCTGGAGCTG GCTACCACGG ACAGTTCCCG TATTCTTGGG GTGGCTACAC GGACATTGAC 
TTGGCTGTGG ATGAAGCAGG CCTCTGGGTC ATTTACAGCA CCGATGAGGC CAAAGGTGCC 
ATTGTCCTCT CCAAACTGAA CCCAGAGAAT CTGGAACTCG AACAAACCTG GGAGACAAAC 
ATCCGTAAGC AGTCAGTCGC CAATGCCTTC ATCATCTGTG GCACCTTGTA CACCGTCAGC 
AGCTACACCT CAGCAGATGC TACCGTCAAC TTTGCTTATG ACACAGGCAC AGGTATCAGC 
AAGACCCTGA CCATCCCATT CAAGAACCGC TATAAGTACA GCAGCATGAT TGACTACAAC 
CCCCTGGAGA AGAAGCTCTT TGCCTGGGAC AACTTGAACA TGGTCACTTA TGACATCAAG 
CTCTCCAAGA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000252.1
CDS	78..1592
Translation	MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM

Target ORF information:

RefSeq Version	NM_000261.2
Organism	Homo sapiens(human)
Definition	Homo sapiens myocilin (MYOC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000261.2

ORF Insert Sequence:

ATGAGGTTCT TCTGTGCACG TTGCTGCAGC TTTGGGCCTG AGATGCCAGC TGTCCAGCTG 
CTGCTTCTGG CCTGCCTGGT GTGGGATGTG GGGGCCAGGA CAGCTCAGCT CAGGAAGGCC 
AATGACCAGA GTGGCCGATG CCAGTATACC TTCAGTGTGG CCAGTCCCAA TGAATCCAGC 
TGCCCAGAGC AGAGCCAGGC CATGTCAGTC ATCCATAACT TACAGAGAGA CAGCAGCACC 
CAACGCTTAG ACCTGGAGGC CACCAAAGCT CGACTCAGCT CCCTGGAGAG CCTCCTCCAC 
CAATTGACCT TGGACCAGGC TGCCAGGCCC CAGGAGACCC AGGAGGGGCT GCAGAGGGAG 
CTGGGCACCC TGAGGCGGGA GCGGGACCAG CTGGAAACCC AAACCAGAGA GTTGGAGACT 
GCCTACAGCA ACCTCCTCCG AGACAAGTCA GTTCTGGAGG AAGAGAAGAA GCGACTAAGG 
CAAGAAAATG AGAATCTGGC CAGGAGGTTG GAAAGCAGCA GCCAGGAGGT AGCAAGGCTG 
AGAAGGGGCC AGTGTCCCCA GACCCGAGAC ACTGCTCGGG CTGTGCCACC AGGCTCCAGA 
GAAGTTTCTA CGTGGAATTT GGACACTTTG GCCTTCCAGG AACTGAAGTC CGAGCTAACT 
GAAGTTCCTG CTTCCCGAAT TTTGAAGGAG AGCCCATCTG GCTATCTCAG GAGTGGAGAG 
GGAGACACCG GATGTGGAGA ACTAGTTTGG GTAGGAGAGC CTCTCACGCT GAGAACAGCA 
GAAACAATTA CTGGCAAGTA TGGTGTGTGG ATGCGAGACC CCAAGCCCAC CTACCCCTAC 
ACCCAGGAGA CCACGTGGAG AATCGACACA GTTGGCACGG ATGTCCGCCA GGTTTTTGAG 
TATGACCTCA TCAGCCAGTT TATGCAGGGC TACCCTTCTA AGGTTCACAT ACTGCCTAGG 
CCACTGGAAA GCACGGGTGC TGTGGTGTAC TCGGGGAGCC TCTATTTCCA GGGCGCTGAG 
TCCAGAACTG TCATAAGATA TGAGCTGAAT ACCGAGACAG TGAAGGCTGA GAAGGAAATC 
CCTGGAGCTG GCTACCACGG ACAGTTCCCG TATTCTTGGG GTGGCTACAC GGACATTGAC 
TTGGCTGTGG ATGAAGCAGG CCTCTGGGTC ATTTACAGCA CCGATGAGGC CAAAGGTGCC 
ATTGTCCTCT CCAAACTGAA CCCAGAGAAT CTGGAACTCG AACAAACCTG GGAGACAAAC 
ATCCGTAAGC AGTCAGTCGC CAATGCCTTC ATCATCTGTG GCACCTTGTA CACCGTCAGC 
AGCTACACCT CAGCAGATGC TACCGTCAAC TTTGCTTATG ACACAGGCAC AGGTATCAGC 
AAGACCCTGA CCATCCCATT CAAGAACCGC TATAAGTACA GCAGCATGAT TGACTACAAC 
CCCCTGGAGA AGAAGCTCTT TGCCTGGGAC AACTTGAACA TGGTCACTTA TGACATCAAG 
CTCTCCAAGA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MYOC ( NM_000261.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_000252.1 Homo sapiens myocilin (MYOC), mRNA.

Price & Availability↑

CloneID	OHu24937
Clone ID Related Accession (Same CDS sequence)	NM_000261.2 , NM_000261.1
Accession Version	NM_000261.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514217600000
Organism	Homo sapiens(human)
Product	myocilin precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF001620.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF001620.1, FJ237046.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153980, SAMEA2154125 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGGTTCT TCTGTGCACG TTGCTGCAGC TTTGGGCCTG AGATGCCAGC TGTCCAGCTG 
CTGCTTCTGG CCTGCCTGGT GTGGGATGTG GGGGCCAGGA CAGCTCAGCT CAGGAAGGCC 
AATGACCAGA GTGGCCGATG CCAGTATACC TTCAGTGTGG CCAGTCCCAA TGAATCCAGC 
TGCCCAGAGC AGAGCCAGGC CATGTCAGTC ATCCATAACT TACAGAGAGA CAGCAGCACC 
CAACGCTTAG ACCTGGAGGC CACCAAAGCT CGACTCAGCT CCCTGGAGAG CCTCCTCCAC 
CAATTGACCT TGGACCAGGC TGCCAGGCCC CAGGAGACCC AGGAGGGGCT GCAGAGGGAG 
CTGGGCACCC TGAGGCGGGA GCGGGACCAG CTGGAAACCC AAACCAGAGA GTTGGAGACT 
GCCTACAGCA ACCTCCTCCG AGACAAGTCA GTTCTGGAGG AAGAGAAGAA GCGACTAAGG 
CAAGAAAATG AGAATCTGGC CAGGAGGTTG GAAAGCAGCA GCCAGGAGGT AGCAAGGCTG 
AGAAGGGGCC AGTGTCCCCA GACCCGAGAC ACTGCTCGGG CTGTGCCACC AGGCTCCAGA 
GAAGTTTCTA CGTGGAATTT GGACACTTTG GCCTTCCAGG AACTGAAGTC CGAGCTAACT 
GAAGTTCCTG CTTCCCGAAT TTTGAAGGAG AGCCCATCTG GCTATCTCAG GAGTGGAGAG 
GGAGACACCG GATGTGGAGA ACTAGTTTGG GTAGGAGAGC CTCTCACGCT GAGAACAGCA 
GAAACAATTA CTGGCAAGTA TGGTGTGTGG ATGCGAGACC CCAAGCCCAC CTACCCCTAC 
ACCCAGGAGA CCACGTGGAG AATCGACACA GTTGGCACGG ATGTCCGCCA GGTTTTTGAG 
TATGACCTCA TCAGCCAGTT TATGCAGGGC TACCCTTCTA AGGTTCACAT ACTGCCTAGG 
CCACTGGAAA GCACGGGTGC TGTGGTGTAC TCGGGGAGCC TCTATTTCCA GGGCGCTGAG 
TCCAGAACTG TCATAAGATA TGAGCTGAAT ACCGAGACAG TGAAGGCTGA GAAGGAAATC 
CCTGGAGCTG GCTACCACGG ACAGTTCCCG TATTCTTGGG GTGGCTACAC GGACATTGAC 
TTGGCTGTGG ATGAAGCAGG CCTCTGGGTC ATTTACAGCA CCGATGAGGC CAAAGGTGCC 
ATTGTCCTCT CCAAACTGAA CCCAGAGAAT CTGGAACTCG AACAAACCTG GGAGACAAAC 
ATCCGTAAGC AGTCAGTCGC CAATGCCTTC ATCATCTGTG GCACCTTGTA CACCGTCAGC 
AGCTACACCT CAGCAGATGC TACCGTCAAC TTTGCTTATG ACACAGGCAC AGGTATCAGC 
AAGACCCTGA CCATCCCATT CAAGAACCGC TATAAGTACA GCAGCATGAT TGACTACAAC 
CCCCTGGAGA AGAAGCTCTT TGCCTGGGAC AACTTGAACA TGGTCACTTA TGACATCAAG 
CTCTCCAAGA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000252.1
CDS	23..1537
Translation	MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM

Target ORF information:

RefSeq Version	NM_000261.1
Organism	Homo sapiens(human)
Definition	Homo sapiens myocilin (MYOC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000261.1

ORF Insert Sequence:

ATGAGGTTCT TCTGTGCACG TTGCTGCAGC TTTGGGCCTG AGATGCCAGC TGTCCAGCTG 
CTGCTTCTGG CCTGCCTGGT GTGGGATGTG GGGGCCAGGA CAGCTCAGCT CAGGAAGGCC 
AATGACCAGA GTGGCCGATG CCAGTATACC TTCAGTGTGG CCAGTCCCAA TGAATCCAGC 
TGCCCAGAGC AGAGCCAGGC CATGTCAGTC ATCCATAACT TACAGAGAGA CAGCAGCACC 
CAACGCTTAG ACCTGGAGGC CACCAAAGCT CGACTCAGCT CCCTGGAGAG CCTCCTCCAC 
CAATTGACCT TGGACCAGGC TGCCAGGCCC CAGGAGACCC AGGAGGGGCT GCAGAGGGAG 
CTGGGCACCC TGAGGCGGGA GCGGGACCAG CTGGAAACCC AAACCAGAGA GTTGGAGACT 
GCCTACAGCA ACCTCCTCCG AGACAAGTCA GTTCTGGAGG AAGAGAAGAA GCGACTAAGG 
CAAGAAAATG AGAATCTGGC CAGGAGGTTG GAAAGCAGCA GCCAGGAGGT AGCAAGGCTG 
AGAAGGGGCC AGTGTCCCCA GACCCGAGAC ACTGCTCGGG CTGTGCCACC AGGCTCCAGA 
GAAGTTTCTA CGTGGAATTT GGACACTTTG GCCTTCCAGG AACTGAAGTC CGAGCTAACT 
GAAGTTCCTG CTTCCCGAAT TTTGAAGGAG AGCCCATCTG GCTATCTCAG GAGTGGAGAG 
GGAGACACCG GATGTGGAGA ACTAGTTTGG GTAGGAGAGC CTCTCACGCT GAGAACAGCA 
GAAACAATTA CTGGCAAGTA TGGTGTGTGG ATGCGAGACC CCAAGCCCAC CTACCCCTAC 
ACCCAGGAGA CCACGTGGAG AATCGACACA GTTGGCACGG ATGTCCGCCA GGTTTTTGAG 
TATGACCTCA TCAGCCAGTT TATGCAGGGC TACCCTTCTA AGGTTCACAT ACTGCCTAGG 
CCACTGGAAA GCACGGGTGC TGTGGTGTAC TCGGGGAGCC TCTATTTCCA GGGCGCTGAG 
TCCAGAACTG TCATAAGATA TGAGCTGAAT ACCGAGACAG TGAAGGCTGA GAAGGAAATC 
CCTGGAGCTG GCTACCACGG ACAGTTCCCG TATTCTTGGG GTGGCTACAC GGACATTGAC 
TTGGCTGTGG ATGAAGCAGG CCTCTGGGTC ATTTACAGCA CCGATGAGGC CAAAGGTGCC 
ATTGTCCTCT CCAAACTGAA CCCAGAGAAT CTGGAACTCG AACAAACCTG GGAGACAAAC 
ATCCGTAAGC AGTCAGTCGC CAATGCCTTC ATCATCTGTG GCACCTTGTA CACCGTCAGC 
AGCTACACCT CAGCAGATGC TACCGTCAAC TTTGCTTATG ACACAGGCAC AGGTATCAGC 
AAGACCCTGA CCATCCCATT CAAGAACCGC TATAAGTACA GCAGCATGAT TGACTACAAC 
CCCCTGGAGA AGAAGCTCTT TGCCTGGGAC AACTTGAACA TGGTCACTTA TGACATCAAG 
CTCTCCAAGA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[Analysis of MYOC gene variants among sporadic patients with primary open-angle glaucoma].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics36(7)662-665(2019 Jul)
Zhang X,Zhang D,Huang L,Hao F,Lin Y,Gong B,Yang Z

Occurrence of MYOC and CYP1B1 variants in juvenile open angle glaucoma Brazilian patients.
Ophthalmic genetics39(6)717-724(2018 12)
Svidnicki PV,Braghini CA,Costa VP,Schimiti RB,de Vasconcellos JPC,de Melo MB

Estimating the age of the p.Cys433Arg variant in the MYOC gene in patients with primary open-angle glaucoma.
PloS one13(11)e0207409(2018)
Marques AM,Ananina G,Costa VP,de Vasconcellos JPC,de Melo MB

Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle.
PloS one13(11)e0206801(2018)
Lynch JM,Dolman AJ,Guo C,Dolan K,Xiang C,Reda S,Li B,Prasanna G

Identification of myocilin as a blood plasma protein and analysis of its role in leukocyte adhesion to endothelial cell monolayers.
PloS one13(12)e0209364(2018)
Aroca-Aguilar JD,Fernández-Navarro A,Ontañón J,Coca-Prados M,Escribano J

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

MYOC cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM