MPO cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MPO
Entrez Gene ID	4353
Full Name	myeloperoxidase
General protein information	Preferred Names myeloperoxidase Names myeloperoxidase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q22
Summary	Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014].
Disorder MIM:	606989
Disorder Html:	Myeloperoxidase deficiency, 254600 (3); {Alzheimer disease, susceptibility to}, 104300 (3); {Lung cancer, protection against, in smokers} (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000250.1	NP_000241.1	myeloperoxidase precursor
NM_000250.2	NP_000241.1	myeloperoxidase precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	MPO	NP_000241.1
Xenopus tropicalis (tropical clawed frog)	mpo	XP_002935236.2
Pan troglodytes (chimpanzee)	MPO	XP_001162602.2
Mus musculus (house mouse)	Mpo	NP_034954.2
Macaca mulatta (Rhesus monkey)	MPO	XP_001103896.2
Xenopus tropicalis (tropical clawed frog)	LOC100496213	XP_002933592.2
Canis lupus familiaris (dog)	MPO	XP_852445.2
Gallus gallus (chicken)	MPO	XP_004946465.1
Bos taurus (cattle)	MPO	NP_001106769.1

Gene Ontology
Bibliography

Related articles in PubMed

Association of myeloperoxidase with cardiovascular disease risk factors in prediabetic subjects.
Mahat RK, Singh N, Rathore V
Diabetes & metabolic syndrome13(1)396-400(2019 Jan - Feb)

Advanced Glycated End Products Alter Neutrophil Effect on Regulation of CD
Lu H, Xu S, Liang X, Dai Y, Huang Z, Ren Y, Lin J, Liu X
Inflammation42(2)559-571(2019 Apr)

Salivary and plasma levels of matrix metalloproteinase-9 and myeloperoxidase at rest and after acute physical exercise in patients with coronary artery disease.
Mahmood Z, Enocsson H, Bäck M, Chung RWS, Lundberg AK, Jonasson L
PloS one14(2)e0207166(2019)

Tracking significant modules and key genes for esophageal squamous cell carcinoma based on differential modules.
Zheng ML, Zhou NK, Luo CH
Journal of cancer research and therapeutics14(Supplement)S1135-S1140(2018 Dec)

Myeloperoxidase activity and acute coronary syndrome survival: long-term evaluation in the ERICO study.
Quidim AV, Bruno TC, Lacerda Leocádio PC, Dos Reis Menta PL, Alvarez-Leite JI, Santos IS, Lotufo PA, Benseñor IM, Goulart AC
Biomarkers in medicine12(11)1219-1229(2018 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MPO gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MPO cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25515	NM_000250.2 Latest version!	Homo sapiens myeloperoxidase (MPO), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu25515	NM_000250.1	Homo sapiens myeloperoxidase (MPO), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MPO ( NM_000250.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_000241.1 Homo sapiens myeloperoxidase (MPO), mRNA.

Price & Availability↑

CloneID	OHu25515
Clone ID Related Accession (Same CDS sequence)	NM_000250.1 , NM_000250.2
Accession Version	NM_000250.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2238bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1552233600000
Organism	Homo sapiens(human)
Product	myeloperoxidase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M19507.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M19507.1, X04876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149004, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGGGGTTC CCTTCTTCTC TTCTCTCAGA TGCATGGTGG ACTTAGGACC TTGCTGGGCT 
GGGGGTCTCA CTGCAGAGAT GAAGCTGCTT CTGGCCCTAG CAGGGCTCCT GGCCATTCTG 
GCCACGCCCC AGCCCTCTGA AGGTGCTGCT CCAGCTGTCC TGGGGGAGGT GGACACCTCG 
TTGGTGCTGA GCTCCATGGA GGAGGCCAAG CAGCTGGTGG ACAAGGCCTA CAAGGAGCGG 
CGGGAAAGCA TCAAGCAGCG GCTTCGCAGC GGCTCAGCCA GCCCCATGGA ACTCCTATCC 
TACTTCAAGC AGCCGGTGGC AGCCACCAGG ACGGCGGTGA GGGCCGCTGA CTACCTGCAC 
GTGGCTCTAG ACCTGCTGGA GAGGAAGCTG CGGTCCCTGT GGCGAAGGCC ATTCAATGTC 
ACTGATGTGC TGACGCCCGC CCAGCTGAAT GTGTTGTCCA AGTCAAGCGG CTGCGCCTAC 
CAGGACGTGG GGGTGACTTG CCCGGAGCAG GACAAATACC GCACCATCAC CGGGATGTGC 
AACAACAGAC GCAGCCCCAC GCTGGGGGCC TCCAACCGTG CCTTTGTGCG CTGGCTGCCG 
GCGGAGTATG AGGACGGCTT CTCTCTTCCC TACGGCTGGA CGCCCGGGGT CAAGCGCAAC 
GGCTTCCCGG TGGCTCTGGC TCGCGCGGTC TCCAACGAGA TCGTGCGCTT CCCCACTGAT 
CAGCTGACTC CGGACCAGGA GCGCTCACTC ATGTTCATGC AATGGGGCCA GCTGTTGGAC 
CACGACCTCG ACTTCACCCC TGAGCCGGCC GCCCGGGCCT CCTTCGTCAC TGGCGTCAAC 
TGCGAGACCA GCTGCGTTCA GCAGCCGCCC TGCTTCCCGC TCAAGATCCC GCCCAATGAC 
CCCCGCATCA AGAACCAAGC CGACTGCATC CCGTTCTTCC GCTCCTGCCC GGCTTGCCCC 
GGGAGCAACA TCACCATCCG CAACCAGATC AACGCGCTCA CTTCCTTCGT GGACGCCAGC 
ATGGTGTACG GCAGCGAGGA GCCCCTGGCC AGGAACCTGC GCAACATGTC CAACCAGCTG 
GGGCTGCTGG CCGTCAACCA GCGCTTCCAA GACAACGGCC GGGCCCTGCT GCCCTTTGAC 
AACCTGCACG ATGACCCCTG TCTCCTCACC AACCGCTCAG CGCGCATCCC CTGCTTCCTG 
GCAGGGGACA CCCGTTCCAG TGAGATGCCC GAGCTCACCT CCATGCACAC CCTCTTACTT 
CGGGAGCACA ACCGGCTGGC CACAGAGCTC AAGAGCCTGA ACCCTAGGTG GGATGGGGAG 
AGGCTCTACC AGGAAGCCCG GAAGATCGTG GGGGCCATGG TCCAGATCAT CACTTACCGG 
GACTACCTGC CCCTGGTGCT GGGGCCAACG GCCATGAGGA AGTACCTGCC CACGTACCGT 
TCCTACAATG ACTCAGTGGA CCCACGCATC GCCAACGTCT TCACCAATGC CTTCCGCTAC 
GGCCACACCC TCATCCAACC CTTCATGTTC CGCCTGGACA ATCGGTACCA GCCCATGGAA 
CCCAACCCCC GTGTCCCCCT CAGCAGGGTC TTTTTTGCCT CCTGGAGGGT CGTGCTGGAA 
GGTGGCATTG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAATCGTCAG 
AACCAAATTG CAGTGGATGA GATCCGGGAG CGATTGTTTG AGCAGGTCAT GAGGATTGGG 
CTGGACCTGC CTGCTCTGAA CATGCAGCGC AGCAGGGACC ACGGCCTCCC AGGATACAAT 
GCCTGGAGGC GCTTCTGTGG GCTCCCGCAG CCTGAAACTG TGGGCCAGCT GGGCACGGTG 
CTGAGGAACC TGAAATTGGC GAGGAAACTG ATGGAGCAGT ATGGCACGCC CAACAACATC 
GACATCTGGA TGGGCGGCGT GTCCGAGCCT CTGAAGCGCA AAGGCCGCGT GGGCCCACTC 
CTCGCCTGCA TCATCGGTAC CCAGTTCAGG AAGCTCCGGG ATGGTGATCG GTTTTGGTGG 
GAGAACGAGG GTGTGTTCAG CATGCAGCAG CGACAGGCCC TGGCCCAGAT CTCATTGCCC 
CGGATCATCT GCGACAACAC AGGCATCACC ACCGTGTCTA AGAACAACAT CTTCATGTCC 
AACTCATATC CCCGGGACTT TGTCAACTGC AGTACACTTC CTGCATTGAA CCTGGCTTCC 
TGGAGGGAAG CCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000241.1
CDS	178..2415
Translation	MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREAS

Target ORF information:

RefSeq Version	NM_000250.1
Organism	Homo sapiens(human)
Definition	Homo sapiens myeloperoxidase (MPO), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000250.1

ORF Insert Sequence:

ATGGGGGTTC CCTTCTTCTC TTCTCTCAGA TGCATGGTGG ACTTAGGACC TTGCTGGGCT 
GGGGGTCTCA CTGCAGAGAT GAAGCTGCTT CTGGCCCTAG CAGGGCTCCT GGCCATTCTG 
GCCACGCCCC AGCCCTCTGA AGGTGCTGCT CCAGCTGTCC TGGGGGAGGT GGACACCTCG 
TTGGTGCTGA GCTCCATGGA GGAGGCCAAG CAGCTGGTGG ACAAGGCCTA CAAGGAGCGG 
CGGGAAAGCA TCAAGCAGCG GCTTCGCAGC GGCTCAGCCA GCCCCATGGA ACTCCTATCC 
TACTTCAAGC AGCCGGTGGC AGCCACCAGG ACGGCGGTGA GGGCCGCTGA CTACCTGCAC 
GTGGCTCTAG ACCTGCTGGA GAGGAAGCTG CGGTCCCTGT GGCGAAGGCC ATTCAATGTC 
ACTGATGTGC TGACGCCCGC CCAGCTGAAT GTGTTGTCCA AGTCAAGCGG CTGCGCCTAC 
CAGGACGTGG GGGTGACTTG CCCGGAGCAG GACAAATACC GCACCATCAC CGGGATGTGC 
AACAACAGAC GCAGCCCCAC GCTGGGGGCC TCCAACCGTG CCTTTGTGCG CTGGCTGCCG 
GCGGAGTATG AGGACGGCTT CTCTCTTCCC TACGGCTGGA CGCCCGGGGT CAAGCGCAAC 
GGCTTCCCGG TGGCTCTGGC TCGCGCGGTC TCCAACGAGA TCGTGCGCTT CCCCACTGAT 
CAGCTGACTC CGGACCAGGA GCGCTCACTC ATGTTCATGC AATGGGGCCA GCTGTTGGAC 
CACGACCTCG ACTTCACCCC TGAGCCGGCC GCCCGGGCCT CCTTCGTCAC TGGCGTCAAC 
TGCGAGACCA GCTGCGTTCA GCAGCCGCCC TGCTTCCCGC TCAAGATCCC GCCCAATGAC 
CCCCGCATCA AGAACCAAGC CGACTGCATC CCGTTCTTCC GCTCCTGCCC GGCTTGCCCC 
GGGAGCAACA TCACCATCCG CAACCAGATC AACGCGCTCA CTTCCTTCGT GGACGCCAGC 
ATGGTGTACG GCAGCGAGGA GCCCCTGGCC AGGAACCTGC GCAACATGTC CAACCAGCTG 
GGGCTGCTGG CCGTCAACCA GCGCTTCCAA GACAACGGCC GGGCCCTGCT GCCCTTTGAC 
AACCTGCACG ATGACCCCTG TCTCCTCACC AACCGCTCAG CGCGCATCCC CTGCTTCCTG 
GCAGGGGACA CCCGTTCCAG TGAGATGCCC GAGCTCACCT CCATGCACAC CCTCTTACTT 
CGGGAGCACA ACCGGCTGGC CACAGAGCTC AAGAGCCTGA ACCCTAGGTG GGATGGGGAG 
AGGCTCTACC AGGAAGCCCG GAAGATCGTG GGGGCCATGG TCCAGATCAT CACTTACCGG 
GACTACCTGC CCCTGGTGCT GGGGCCAACG GCCATGAGGA AGTACCTGCC CACGTACCGT 
TCCTACAATG ACTCAGTGGA CCCACGCATC GCCAACGTCT TCACCAATGC CTTCCGCTAC 
GGCCACACCC TCATCCAACC CTTCATGTTC CGCCTGGACA ATCGGTACCA GCCCATGGAA 
CCCAACCCCC GTGTCCCCCT CAGCAGGGTC TTTTTTGCCT CCTGGAGGGT CGTGCTGGAA 
GGTGGCATTG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAATCGTCAG 
AACCAAATTG CAGTGGATGA GATCCGGGAG CGATTGTTTG AGCAGGTCAT GAGGATTGGG 
CTGGACCTGC CTGCTCTGAA CATGCAGCGC AGCAGGGACC ACGGCCTCCC AGGATACAAT 
GCCTGGAGGC GCTTCTGTGG GCTCCCGCAG CCTGAAACTG TGGGCCAGCT GGGCACGGTG 
CTGAGGAACC TGAAATTGGC GAGGAAACTG ATGGAGCAGT ATGGCACGCC CAACAACATC 
GACATCTGGA TGGGCGGCGT GTCCGAGCCT CTGAAGCGCA AAGGCCGCGT GGGCCCACTC 
CTCGCCTGCA TCATCGGTAC CCAGTTCAGG AAGCTCCGGG ATGGTGATCG GTTTTGGTGG 
GAGAACGAGG GTGTGTTCAG CATGCAGCAG CGACAGGCCC TGGCCCAGAT CTCATTGCCC 
CGGATCATCT GCGACAACAC AGGCATCACC ACCGTGTCTA AGAACAACAT CTTCATGTCC 
AACTCATATC CCCGGGACTT TGTCAACTGC AGTACACTTC CTGCATTGAA CCTGGCTTCC 
TGGAGGGAAG CCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MPO ( NM_000250.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_000241.1 Homo sapiens myeloperoxidase (MPO), mRNA.

Price & Availability↑

CloneID	OHu25515
Clone ID Related Accession (Same CDS sequence)	NM_000250.1 , NM_000250.2
Accession Version	NM_000250.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2238bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572796800000
Organism	Homo sapiens(human)
Product	myeloperoxidase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M19507.1 and AC004687.2. On May 17, 2019 this sequence version replaced NM_000250.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M19507.1, X04876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149004, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology MANE Ensembl match :: ENST00000225275.4/ ENSP00000225275.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGGGGTTC CCTTCTTCTC TTCTCTCAGA TGCATGGTGG ACTTAGGACC TTGCTGGGCT 
GGGGGTCTCA CTGCAGAGAT GAAGCTGCTT CTGGCCCTAG CAGGGCTCCT GGCCATTCTG 
GCCACGCCCC AGCCCTCTGA AGGTGCTGCT CCAGCTGTCC TGGGGGAGGT GGACACCTCG 
TTGGTGCTGA GCTCCATGGA GGAGGCCAAG CAGCTGGTGG ACAAGGCCTA CAAGGAGCGG 
CGGGAAAGCA TCAAGCAGCG GCTTCGCAGC GGCTCAGCCA GCCCCATGGA ACTCCTATCC 
TACTTCAAGC AGCCGGTGGC AGCCACCAGG ACGGCGGTGA GGGCCGCTGA CTACCTGCAC 
GTGGCTCTAG ACCTGCTGGA GAGGAAGCTG CGGTCCCTGT GGCGAAGGCC ATTCAATGTC 
ACTGATGTGC TGACGCCCGC CCAGCTGAAT GTGTTGTCCA AGTCAAGCGG CTGCGCCTAC 
CAGGACGTGG GGGTGACTTG CCCGGAGCAG GACAAATACC GCACCATCAC CGGGATGTGC 
AACAACAGAC GCAGCCCCAC GCTGGGGGCC TCCAACCGTG CCTTTGTGCG CTGGCTGCCG 
GCGGAGTATG AGGACGGCTT CTCTCTTCCC TACGGCTGGA CGCCCGGGGT CAAGCGCAAC 
GGCTTCCCGG TGGCTCTGGC TCGCGCGGTC TCCAACGAGA TCGTGCGCTT CCCCACTGAT 
CAGCTGACTC CGGACCAGGA GCGCTCACTC ATGTTCATGC AATGGGGCCA GCTGTTGGAC 
CACGACCTCG ACTTCACCCC TGAGCCGGCC GCCCGGGCCT CCTTCGTCAC TGGCGTCAAC 
TGCGAGACCA GCTGCGTTCA GCAGCCGCCC TGCTTCCCGC TCAAGATCCC GCCCAATGAC 
CCCCGCATCA AGAACCAAGC CGACTGCATC CCGTTCTTCC GCTCCTGCCC GGCTTGCCCC 
GGGAGCAACA TCACCATCCG CAACCAGATC AACGCGCTCA CTTCCTTCGT GGACGCCAGC 
ATGGTGTACG GCAGCGAGGA GCCCCTGGCC AGGAACCTGC GCAACATGTC CAACCAGCTG 
GGGCTGCTGG CCGTCAACCA GCGCTTCCAA GACAACGGCC GGGCCCTGCT GCCCTTTGAC 
AACCTGCACG ATGACCCCTG TCTCCTCACC AACCGCTCAG CGCGCATCCC CTGCTTCCTG 
GCAGGGGACA CCCGTTCCAG TGAGATGCCC GAGCTCACCT CCATGCACAC CCTCTTACTT 
CGGGAGCACA ACCGGCTGGC CACAGAGCTC AAGAGCCTGA ACCCTAGGTG GGATGGGGAG 
AGGCTCTACC AGGAAGCCCG GAAGATCGTG GGGGCCATGG TCCAGATCAT CACTTACCGG 
GACTACCTGC CCCTGGTGCT GGGGCCAACG GCCATGAGGA AGTACCTGCC CACGTACCGT 
TCCTACAATG ACTCAGTGGA CCCACGCATC GCCAACGTCT TCACCAATGC CTTCCGCTAC 
GGCCACACCC TCATCCAACC CTTCATGTTC CGCCTGGACA ATCGGTACCA GCCCATGGAA 
CCCAACCCCC GTGTCCCCCT CAGCAGGGTC TTTTTTGCCT CCTGGAGGGT CGTGCTGGAA 
GGTGGCATTG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAATCGTCAG 
AACCAAATTG CAGTGGATGA GATCCGGGAG CGATTGTTTG AGCAGGTCAT GAGGATTGGG 
CTGGACCTGC CTGCTCTGAA CATGCAGCGC AGCAGGGACC ACGGCCTCCC AGGATACAAT 
GCCTGGAGGC GCTTCTGTGG GCTCCCGCAG CCTGAAACTG TGGGCCAGCT GGGCACGGTG 
CTGAGGAACC TGAAATTGGC GAGGAAACTG ATGGAGCAGT ATGGCACGCC CAACAACATC 
GACATCTGGA TGGGCGGCGT GTCCGAGCCT CTGAAGCGCA AAGGCCGCGT GGGCCCACTC 
CTCGCCTGCA TCATCGGTAC CCAGTTCAGG AAGCTCCGGG ATGGTGATCG GTTTTGGTGG 
GAGAACGAGG GTGTGTTCAG CATGCAGCAG CGACAGGCCC TGGCCCAGAT CTCATTGCCC 
CGGATCATCT GCGACAACAC AGGCATCACC ACCGTGTCTA AGAACAACAT CTTCATGTCC 
AACTCATATC CCCGGGACTT TGTCAACTGC AGTACACTTC CTGCATTGAA CCTGGCTTCC 
TGGAGGGAAG CCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000241.1
CDS	178..2415
Translation	MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREAS

Target ORF information:

RefSeq Version	NM_000250.2
Organism	Homo sapiens(human)
Definition	Homo sapiens myeloperoxidase (MPO), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000250.2

ORF Insert Sequence:

ATGGGGGTTC CCTTCTTCTC TTCTCTCAGA TGCATGGTGG ACTTAGGACC TTGCTGGGCT 
GGGGGTCTCA CTGCAGAGAT GAAGCTGCTT CTGGCCCTAG CAGGGCTCCT GGCCATTCTG 
GCCACGCCCC AGCCCTCTGA AGGTGCTGCT CCAGCTGTCC TGGGGGAGGT GGACACCTCG 
TTGGTGCTGA GCTCCATGGA GGAGGCCAAG CAGCTGGTGG ACAAGGCCTA CAAGGAGCGG 
CGGGAAAGCA TCAAGCAGCG GCTTCGCAGC GGCTCAGCCA GCCCCATGGA ACTCCTATCC 
TACTTCAAGC AGCCGGTGGC AGCCACCAGG ACGGCGGTGA GGGCCGCTGA CTACCTGCAC 
GTGGCTCTAG ACCTGCTGGA GAGGAAGCTG CGGTCCCTGT GGCGAAGGCC ATTCAATGTC 
ACTGATGTGC TGACGCCCGC CCAGCTGAAT GTGTTGTCCA AGTCAAGCGG CTGCGCCTAC 
CAGGACGTGG GGGTGACTTG CCCGGAGCAG GACAAATACC GCACCATCAC CGGGATGTGC 
AACAACAGAC GCAGCCCCAC GCTGGGGGCC TCCAACCGTG CCTTTGTGCG CTGGCTGCCG 
GCGGAGTATG AGGACGGCTT CTCTCTTCCC TACGGCTGGA CGCCCGGGGT CAAGCGCAAC 
GGCTTCCCGG TGGCTCTGGC TCGCGCGGTC TCCAACGAGA TCGTGCGCTT CCCCACTGAT 
CAGCTGACTC CGGACCAGGA GCGCTCACTC ATGTTCATGC AATGGGGCCA GCTGTTGGAC 
CACGACCTCG ACTTCACCCC TGAGCCGGCC GCCCGGGCCT CCTTCGTCAC TGGCGTCAAC 
TGCGAGACCA GCTGCGTTCA GCAGCCGCCC TGCTTCCCGC TCAAGATCCC GCCCAATGAC 
CCCCGCATCA AGAACCAAGC CGACTGCATC CCGTTCTTCC GCTCCTGCCC GGCTTGCCCC 
GGGAGCAACA TCACCATCCG CAACCAGATC AACGCGCTCA CTTCCTTCGT GGACGCCAGC 
ATGGTGTACG GCAGCGAGGA GCCCCTGGCC AGGAACCTGC GCAACATGTC CAACCAGCTG 
GGGCTGCTGG CCGTCAACCA GCGCTTCCAA GACAACGGCC GGGCCCTGCT GCCCTTTGAC 
AACCTGCACG ATGACCCCTG TCTCCTCACC AACCGCTCAG CGCGCATCCC CTGCTTCCTG 
GCAGGGGACA CCCGTTCCAG TGAGATGCCC GAGCTCACCT CCATGCACAC CCTCTTACTT 
CGGGAGCACA ACCGGCTGGC CACAGAGCTC AAGAGCCTGA ACCCTAGGTG GGATGGGGAG 
AGGCTCTACC AGGAAGCCCG GAAGATCGTG GGGGCCATGG TCCAGATCAT CACTTACCGG 
GACTACCTGC CCCTGGTGCT GGGGCCAACG GCCATGAGGA AGTACCTGCC CACGTACCGT 
TCCTACAATG ACTCAGTGGA CCCACGCATC GCCAACGTCT TCACCAATGC CTTCCGCTAC 
GGCCACACCC TCATCCAACC CTTCATGTTC CGCCTGGACA ATCGGTACCA GCCCATGGAA 
CCCAACCCCC GTGTCCCCCT CAGCAGGGTC TTTTTTGCCT CCTGGAGGGT CGTGCTGGAA 
GGTGGCATTG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAATCGTCAG 
AACCAAATTG CAGTGGATGA GATCCGGGAG CGATTGTTTG AGCAGGTCAT GAGGATTGGG 
CTGGACCTGC CTGCTCTGAA CATGCAGCGC AGCAGGGACC ACGGCCTCCC AGGATACAAT 
GCCTGGAGGC GCTTCTGTGG GCTCCCGCAG CCTGAAACTG TGGGCCAGCT GGGCACGGTG 
CTGAGGAACC TGAAATTGGC GAGGAAACTG ATGGAGCAGT ATGGCACGCC CAACAACATC 
GACATCTGGA TGGGCGGCGT GTCCGAGCCT CTGAAGCGCA AAGGCCGCGT GGGCCCACTC 
CTCGCCTGCA TCATCGGTAC CCAGTTCAGG AAGCTCCGGG ATGGTGATCG GTTTTGGTGG 
GAGAACGAGG GTGTGTTCAG CATGCAGCAG CGACAGGCCC TGGCCCAGAT CTCATTGCCC 
CGGATCATCT GCGACAACAC AGGCATCACC ACCGTGTCTA AGAACAACAT CTTCATGTCC 
AACTCATATC CCCGGGACTT TGTCAACTGC AGTACACTTC CTGCATTGAA CCTGGCTTCC 
TGGAGGGAAG CCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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Salivary and plasma levels of matrix metalloproteinase-9 and myeloperoxidase at rest and after acute physical exercise in patients with coronary artery disease.
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Tracking significant modules and key genes for esophageal squamous cell carcinoma based on differential modules.
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Quidim AV,Bruno TC,Lacerda Leocádio PC,Dos Reis Menta PL,Alvarez-Leite JI,Santos IS,Lotufo PA,Benseñor IM,Goulart AC

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MPO cDNA ORF clone, Homo sapiens(human)

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