MICB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MICB
Entrez Gene ID	4277
Full Name	MHC class I polypeptide-related sequence B
Synonyms	PERB11.2
General protein information	Preferred Names MHC class I polypeptide-related sequence B Names MHC class I polypeptide-related sequence B MHC class I chain-related protein B MHC class I mic-B antigen MHC class I-like molecule PERB11.2-IMX stress inducible class I homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.33
Summary	This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
Disorder MIM:	602436

mRNA and Protein(s)

mRNA	Protein	Name
NM_005931.4	NP_005922.2	MHC class I polypeptide-related sequence B isoform 1 precursor
NM_005931.5	NP_005922.2	MHC class I polypeptide-related sequence B isoform 1 precursor
NM_001289161.2	NP_001276090.1	MHC class I polypeptide-related sequence B isoform 3 precursor
NM_001289160.1	NP_001276089.1	MHC class I polypeptide-related sequence B isoform 2
NM_001289161.1	NP_001276090.1	MHC class I polypeptide-related sequence B isoform 3 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MICB	NP_001038959.1
Mus musculus (house mouse)	Mill2	NP_715641.1
Macaca mulatta (Rhesus monkey)	CD9	NP_001108437.1
Bos taurus (cattle)	MIC1	NP_001120789.1
Rattus norvegicus (Norway rat)	Micb	NP_001017468.1
Homo sapiens (human)	MICB	NP_005922.2
Macaca mulatta (Rhesus monkey)	MICB	NP_001108428.1

Gene Ontology
Bibliography

Related articles in PubMed

Diversity and characterisation of polymorphic 3' untranslated region haplotypes of MICA and MICB genes.
Cox ST, Hernandez D, Danby R, Turner TR, Madrigal JA
HLA92(6)392-402(2018 12)

MicroRNA-34a promotes MICB expression in hepatocytes.
Zhou MT, Zhao C, Chen X, Zhang HC, Li G, Lou H, Huang WJ, Wei LJ, Li DW, Wu X, Zhang ZC, Liu H, Ou R, Yang WJ, Hu S, Xu Y, Tang KF
Carcinogenesis39(12)1477-1487(2018 12)

Genetic polymorphism analysis of MICB gene in Jing ethnic minority of Southern China.
Liu X, Chen X, Wei X, Meng Y, Liu L, Dai S
HLA92(4)224-230(2018 10)

Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis.
Cahill ME, Conley S, DeWan AT, Montgomery RR
BMC infectious diseases18(1)282(2018 06)

Association of MICA and MICB polymorphisms with the susceptibility of leukemia in Korean patients.
Baek IC, Shin DH, Choi EJ, Kim HJ, Yoon JH, Cho BS, Kim YJ, Lee S, Min WS, Kim HJ, Kim TG
Blood cancer journal8(6)58(2018 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MICB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MICB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15606	NM_001289160.1 Latest version!	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu15629	NM_001289161.2 Latest version!	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu21386	NM_005931.5 Latest version!	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$258.30 $369.00
View Old Accession Versions >>
OHu21386	NM_005931.4	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$258.30 $369.00
OHu15629	NM_001289161.1	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MICB ( NM_001289160.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276089.1 Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15606
Clone ID Related Accession (Same CDS sequence)	NM_001289160.1
Accession Version	NM_001289160.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569254400000
Organism	Homo sapiens(human)
Product	MHC class I polypeptide-related sequence B isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB121254.1, AK300791.1, DC364717.1, AK303655.1, CN389975.1, BC044218.1 and BQ216247.1. On or before Jan 16, 2014 this sequence version replaced XM_005249125.1, XM_005272818.1, XM_005274863.1, XM_005275250.1, XM_005275408.1, XM_005275556.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300791.1, SRR1163658.57237.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCTGT CCCAGGATGG ATCTGTGCAG TCAGGGTTTC TCGCTGAGGG ACATCTGGAT 
GGTCAGCCCT TCCTGCGCTA TGACAGGCAG AAACGCAGGG CAAAGCCCCA GGGACAGTGG 
GCAGAAAATG TCCTGGGAGC TAAGACCTGG GACACAGAGA CCGAGGACTT GACAGAGAAT 
GGGCAAGACC TCAGGAGGAC CCTGACTCAT ATCAAGGACC AGAAAGGAGG CTTGCATTCC 
CTCCAGGAGA TTAGGGTCTG TGAGATCCAT GAAGACAGCA GCACCAGGGG CTCCCGGCAT 
TTCTACTACG ATGGGGAGCT CTTCCTCTCC CAAAACCTGG AGACTCAAGA ATCGACAGTG 
CCCCAGTCCT CCAGAGCTCA GACCTTGGCT ATGAACGTCA CAAATTTCTG GAAGGAAGAT 
GCCATGAAGA CCAAGACACA CTATCGCGCT ATGCAGGCAG ACTGCCTGCA GAAACTACAG 
CGATATCTGA AATCCGGGGT GGCCATCAGG AGAACAGTGC CCCCCATGGT GAATGTCACC 
TGCAGCGAGG TCTCAGAGGG CAACATCACC GTGACATGCA GGGCTTCCAG CTTCTATCCC 
CGGAATATCA CACTGACCTG GCGTCAGGAT GGGGTATCTT TGAGCCACAA CACCCAGCAG 
TGGGGGGATG TCCTGCCTGA TGGGAATGGA ACCTACCAGA CCTGGGTGGC CACCAGGATT 
CGCCAAGGAG AGGAGCAGAG GTTCACCTGC TACATGGAAC ACAGCGGGAA TCACGGCACT 
CACCCTGTGC CCTCTGGGAA GGCGCTGGTG CTTCAGAGTC AACGGACAGA CTTTCCATAT 
GTTTCTGCTG CTATGCCATG TTTTGTTATT ATTATTATTC TCTGTGTCCC TTGTTGCAAG 
AAGAAAACAT CAGCGGCAGA GGGTCCAGAG CTTGTGAGCC TGCAGGTCCT GGATCAACAC 
CCAGTTGGGA CAGGAGACCA CAGGGATGCA GCACAGCTGG GATTTCAGCC TCTGATGTCA 
GCTACTGGGT CCACTGGTTC CACTGAGGGC ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276089.1
CDS	142..1197
Translation	MVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGT

Target ORF information:

RefSeq Version	NM_001289160.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289160.1

ORF Insert Sequence:

ATGGTGCTGT CCCAGGATGG ATCTGTGCAG TCAGGGTTTC TCGCTGAGGG ACATCTGGAT 
GGTCAGCCCT TCCTGCGCTA TGACAGGCAG AAACGCAGGG CAAAGCCCCA GGGACAGTGG 
GCAGAAAATG TCCTGGGAGC TAAGACCTGG GACACAGAGA CCGAGGACTT GACAGAGAAT 
GGGCAAGACC TCAGGAGGAC CCTGACTCAT ATCAAGGACC AGAAAGGAGG CTTGCATTCC 
CTCCAGGAGA TTAGGGTCTG TGAGATCCAT GAAGACAGCA GCACCAGGGG CTCCCGGCAT 
TTCTACTACG ATGGGGAGCT CTTCCTCTCC CAAAACCTGG AGACTCAAGA ATCGACAGTG 
CCCCAGTCCT CCAGAGCTCA GACCTTGGCT ATGAACGTCA CAAATTTCTG GAAGGAAGAT 
GCCATGAAGA CCAAGACACA CTATCGCGCT ATGCAGGCAG ACTGCCTGCA GAAACTACAG 
CGATATCTGA AATCCGGGGT GGCCATCAGG AGAACAGTGC CCCCCATGGT GAATGTCACC 
TGCAGCGAGG TCTCAGAGGG CAACATCACC GTGACATGCA GGGCTTCCAG CTTCTATCCC 
CGGAATATCA CACTGACCTG GCGTCAGGAT GGGGTATCTT TGAGCCACAA CACCCAGCAG 
TGGGGGGATG TCCTGCCTGA TGGGAATGGA ACCTACCAGA CCTGGGTGGC CACCAGGATT 
CGCCAAGGAG AGGAGCAGAG GTTCACCTGC TACATGGAAC ACAGCGGGAA TCACGGCACT 
CACCCTGTGC CCTCTGGGAA GGCGCTGGTG CTTCAGAGTC AACGGACAGA CTTTCCATAT 
GTTTCTGCTG CTATGCCATG TTTTGTTATT ATTATTATTC TCTGTGTCCC TTGTTGCAAG 
AAGAAAACAT CAGCGGCAGA GGGTCCAGAG CTTGTGAGCC TGCAGGTCCT GGATCAACAC 
CCAGTTGGGA CAGGAGACCA CAGGGATGCA GCACAGCTGG GATTTCAGCC TCTGATGTCA 
GCTACTGGGT CCACTGGTTC CACTGAGGGC ACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MICB ( NM_001289161.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276090.1 Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15629
Clone ID Related Accession (Same CDS sequence)	NM_001289161.2 , NM_001289161.1
Accession Version	NM_001289161.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569513600000
Organism	Homo sapiens(human)
Product	MHC class I polypeptide-related sequence B isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC044218.1, DC364717.1, CN389975.1 and BQ216247.1. On May 31, 2019 this sequence version replaced NM_001289161.1. Transcript Variant: This variant (3) contains an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform 3, which is shorter than isofom 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044218.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGTGCCC CAGTCCTCCA GAGCTCAGAC CTTGGCTATG 
AACGTCACAA ATTTCTGGAA GGAAGATGCC ATGAAGACCA AGACACACTA TCGCGCTATG 
CAGGCAGACT GCCTGCAGAA ACTACAGCGA TATCTGAAAT CCGGGGTGGC CATCAGGAGA 
ACAGTGCCCC CCATGGTGAA TGTCACCTGC AGCGAGGTCT CAGAGGGCAA CATCACCGTG 
ACATGCAGGG CTTCCAGCTT CTATCCCCGG AATATCACAC TGACCTGGCG TCAGGATGGG 
GTATCTTTGA GCCACAACAC CCAGCAGTGG GGGGATGTCC TGCCTGATGG GAATGGAACC 
TACCAGACCT GGGTGGCCAC CAGGATTCGC CAAGGAGAGG AGCAGAGGTT CACCTGCTAC 
ATGGAACACA GCGGGAATCA CGGCACTCAC CCTGTGCCCT CTGGGAAGGC GCTGGTGCTT 
CAGAGTCAAC GGACAGACTT TCCATATGTT TCTGCTGCTA TGCCATGTTT TGTTATTATT 
ATTATTCTCT GTGTCCCTTG TTGCAAGAAG AAAACATCAG CGGCAGAGGG TCCAGAGCTT 
GTGAGCCTGC AGGTCCTGGA TCAACACCCA GTTGGGACAG GAGACCACAG GGATGCAGCA 
CAGCTGGGAT TTCAGCCTCT GATGTCAGCT ACTGGGTCCA CTGGTTCCAC TGAGGGCACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276090.1
CDS	50..1072
Translation	MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGT

Target ORF information:

RefSeq Version	NM_001289161.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289161.2

ORF Insert Sequence:

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGTGCCC CAGTCCTCCA GAGCTCAGAC CTTGGCTATG 
AACGTCACAA ATTTCTGGAA GGAAGATGCC ATGAAGACCA AGACACACTA TCGCGCTATG 
CAGGCAGACT GCCTGCAGAA ACTACAGCGA TATCTGAAAT CCGGGGTGGC CATCAGGAGA 
ACAGTGCCCC CCATGGTGAA TGTCACCTGC AGCGAGGTCT CAGAGGGCAA CATCACCGTG 
ACATGCAGGG CTTCCAGCTT CTATCCCCGG AATATCACAC TGACCTGGCG TCAGGATGGG 
GTATCTTTGA GCCACAACAC CCAGCAGTGG GGGGATGTCC TGCCTGATGG GAATGGAACC 
TACCAGACCT GGGTGGCCAC CAGGATTCGC CAAGGAGAGG AGCAGAGGTT CACCTGCTAC 
ATGGAACACA GCGGGAATCA CGGCACTCAC CCTGTGCCCT CTGGGAAGGC GCTGGTGCTT 
CAGAGTCAAC GGACAGACTT TCCATATGTT TCTGCTGCTA TGCCATGTTT TGTTATTATT 
ATTATTCTCT GTGTCCCTTG TTGCAAGAAG AAAACATCAG CGGCAGAGGG TCCAGAGCTT 
GTGAGCCTGC AGGTCCTGGA TCAACACCCA GTTGGGACAG GAGACCACAG GGATGCAGCA 
CAGCTGGGAT TTCAGCCTCT GATGTCAGCT ACTGGGTCCA CTGGTTCCAC TGAGGGCACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MICB ( NM_001289161.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276090.1 Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15629
Clone ID Related Accession (Same CDS sequence)	NM_001289161.2 , NM_001289161.1
Accession Version	NM_001289161.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530288000000
Organism	Homo sapiens(human)
Product	MHC class I polypeptide-related sequence B isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL663061.8, BC044218.1, DC364717.1, CN389975.1 and BQ216247.1. On or before Jan 16, 2014 this sequence version replaced XM_005249126.1, XM_005272819.1, XM_005274864.1, XM_005274976.1, XM_005275251.1, XM_005275409.1, XM_005275557.1. Transcript Variant: This variant (3) contains an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform 3, which is shorter than isofom 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044218.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGTGCCC CAGTCCTCCA GAGCTCAGAC CTTGGCTATG 
AACGTCACAA ATTTCTGGAA GGAAGATGCC ATGAAGACCA AGACACACTA TCGCGCTATG 
CAGGCAGACT GCCTGCAGAA ACTACAGCGA TATCTGAAAT CCGGGGTGGC CATCAGGAGA 
ACAGTGCCCC CCATGGTGAA TGTCACCTGC AGCGAGGTCT CAGAGGGCAA CATCACCGTG 
ACATGCAGGG CTTCCAGCTT CTATCCCCGG AATATCACAC TGACCTGGCG TCAGGATGGG 
GTATCTTTGA GCCACAACAC CCAGCAGTGG GGGGATGTCC TGCCTGATGG GAATGGAACC 
TACCAGACCT GGGTGGCCAC CAGGATTCGC CAAGGAGAGG AGCAGAGGTT CACCTGCTAC 
ATGGAACACA GCGGGAATCA CGGCACTCAC CCTGTGCCCT CTGGGAAGGC GCTGGTGCTT 
CAGAGTCAAC GGACAGACTT TCCATATGTT TCTGCTGCTA TGCCATGTTT TGTTATTATT 
ATTATTCTCT GTGTCCCTTG TTGCAAGAAG AAAACATCAG CGGCAGAGGG TCCAGAGCTT 
GTGAGCCTGC AGGTCCTGGA TCAACACCCA GTTGGGACAG GAGACCACAG GGATGCAGCA 
CAGCTGGGAT TTCAGCCTCT GATGTCAGCT ACTGGGTCCA CTGGTTCCAC TGAGGGCACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276090.1
CDS	145..1167
Translation	MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGT

Target ORF information:

RefSeq Version	NM_001289161.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289161.1

ORF Insert Sequence:

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGTGCCC CAGTCCTCCA GAGCTCAGAC CTTGGCTATG 
AACGTCACAA ATTTCTGGAA GGAAGATGCC ATGAAGACCA AGACACACTA TCGCGCTATG 
CAGGCAGACT GCCTGCAGAA ACTACAGCGA TATCTGAAAT CCGGGGTGGC CATCAGGAGA 
ACAGTGCCCC CCATGGTGAA TGTCACCTGC AGCGAGGTCT CAGAGGGCAA CATCACCGTG 
ACATGCAGGG CTTCCAGCTT CTATCCCCGG AATATCACAC TGACCTGGCG TCAGGATGGG 
GTATCTTTGA GCCACAACAC CCAGCAGTGG GGGGATGTCC TGCCTGATGG GAATGGAACC 
TACCAGACCT GGGTGGCCAC CAGGATTCGC CAAGGAGAGG AGCAGAGGTT CACCTGCTAC 
ATGGAACACA GCGGGAATCA CGGCACTCAC CCTGTGCCCT CTGGGAAGGC GCTGGTGCTT 
CAGAGTCAAC GGACAGACTT TCCATATGTT TCTGCTGCTA TGCCATGTTT TGTTATTATT 
ATTATTCTCT GTGTCCCTTG TTGCAAGAAG AAAACATCAG CGGCAGAGGG TCCAGAGCTT 
GTGAGCCTGC AGGTCCTGGA TCAACACCCA GTTGGGACAG GAGACCACAG GGATGCAGCA 
CAGCTGGGAT TTCAGCCTCT GATGTCAGCT ACTGGGTCCA CTGGTTCCAC TGAGGGCACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MICB ( NM_005931.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005922.2 Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21386
Clone ID Related Accession (Same CDS sequence)	NM_005931.4 , NM_005931.5
Accession Version	NM_005931.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1510329600000
Organism	Homo sapiens(human)
Product	MHC class I polypeptide-related sequence B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL663061.8, AK314228.1, DC364717.1, CN389975.1, BC044218.1 and BQ216247.1. This sequence is a reference standard in the RefSeqGene project. On Jan 16, 2014 this sequence version replaced NM_005931.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291927.1, X91625.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGGCTTG CATTCCCTCC AGGAGATTAG GGTCTGTGAG 
ATCCATGAAG ACAGCAGCAC CAGGGGCTCC CGGCATTTCT ACTACGATGG GGAGCTCTTC 
CTCTCCCAAA ACCTGGAGAC TCAAGAATCG ACAGTGCCCC AGTCCTCCAG AGCTCAGACC 
TTGGCTATGA ACGTCACAAA TTTCTGGAAG GAAGATGCCA TGAAGACCAA GACACACTAT 
CGCGCTATGC AGGCAGACTG CCTGCAGAAA CTACAGCGAT ATCTGAAATC CGGGGTGGCC 
ATCAGGAGAA CAGTGCCCCC CATGGTGAAT GTCACCTGCA GCGAGGTCTC AGAGGGCAAC 
ATCACCGTGA CATGCAGGGC TTCCAGCTTC TATCCCCGGA ATATCACACT GACCTGGCGT 
CAGGATGGGG TATCTTTGAG CCACAACACC CAGCAGTGGG GGGATGTCCT GCCTGATGGG 
AATGGAACCT ACCAGACCTG GGTGGCCACC AGGATTCGCC AAGGAGAGGA GCAGAGGTTC 
ACCTGCTACA TGGAACACAG CGGGAATCAC GGCACTCACC CTGTGCCCTC TGGGAAGGCG 
CTGGTGCTTC AGAGTCAACG GACAGACTTT CCATATGTTT CTGCTGCTAT GCCATGTTTT 
GTTATTATTA TTATTCTCTG TGTCCCTTGT TGCAAGAAGA AAACATCAGC GGCAGAGGGT 
CCAGAGCTTG TGAGCCTGCA GGTCCTGGAT CAACACCCAG TTGGGACAGG AGACCACAGG 
GATGCAGCAC AGCTGGGATT TCAGCCTCTG ATGTCAGCTA CTGGGTCCAC TGGTTCCACT 
GAGGGCACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005922.2
CDS	145..1296
Translation	MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGT

Target ORF information:

RefSeq Version	NM_005931.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005931.4

ORF Insert Sequence:

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGGCTTG CATTCCCTCC AGGAGATTAG GGTCTGTGAG 
ATCCATGAAG ACAGCAGCAC CAGGGGCTCC CGGCATTTCT ACTACGATGG GGAGCTCTTC 
CTCTCCCAAA ACCTGGAGAC TCAAGAATCG ACAGTGCCCC AGTCCTCCAG AGCTCAGACC 
TTGGCTATGA ACGTCACAAA TTTCTGGAAG GAAGATGCCA TGAAGACCAA GACACACTAT 
CGCGCTATGC AGGCAGACTG CCTGCAGAAA CTACAGCGAT ATCTGAAATC CGGGGTGGCC 
ATCAGGAGAA CAGTGCCCCC CATGGTGAAT GTCACCTGCA GCGAGGTCTC AGAGGGCAAC 
ATCACCGTGA CATGCAGGGC TTCCAGCTTC TATCCCCGGA ATATCACACT GACCTGGCGT 
CAGGATGGGG TATCTTTGAG CCACAACACC CAGCAGTGGG GGGATGTCCT GCCTGATGGG 
AATGGAACCT ACCAGACCTG GGTGGCCACC AGGATTCGCC AAGGAGAGGA GCAGAGGTTC 
ACCTGCTACA TGGAACACAG CGGGAATCAC GGCACTCACC CTGTGCCCTC TGGGAAGGCG 
CTGGTGCTTC AGAGTCAACG GACAGACTTT CCATATGTTT CTGCTGCTAT GCCATGTTTT 
GTTATTATTA TTATTCTCTG TGTCCCTTGT TGCAAGAAGA AAACATCAGC GGCAGAGGGT 
CCAGAGCTTG TGAGCCTGCA GGTCCTGGAT CAACACCCAG TTGGGACAGG AGACCACAGG 
GATGCAGCAC AGCTGGGATT TCAGCCTCTG ATGTCAGCTA CTGGGTCCAC TGGTTCCACT 
GAGGGCACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MICB ( NM_005931.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005922.2 Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.

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CloneID	OHu21386
Clone ID Related Accession (Same CDS sequence)	NM_005931.4 , NM_005931.5
Accession Version	NM_005931.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569427200000
Organism	Homo sapiens(human)
Product	MHC class I polypeptide-related sequence B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314228.1, DC364717.1, CN389975.1, BC044218.1 and BQ216247.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_005931.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314228.1, X91625.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000252229.7/ ENSP00000252229.6 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGGCTTG CATTCCCTCC AGGAGATTAG GGTCTGTGAG 
ATCCATGAAG ACAGCAGCAC CAGGGGCTCC CGGCATTTCT ACTACGATGG GGAGCTCTTC 
CTCTCCCAAA ACCTGGAGAC TCAAGAATCG ACAGTGCCCC AGTCCTCCAG AGCTCAGACC 
TTGGCTATGA ACGTCACAAA TTTCTGGAAG GAAGATGCCA TGAAGACCAA GACACACTAT 
CGCGCTATGC AGGCAGACTG CCTGCAGAAA CTACAGCGAT ATCTGAAATC CGGGGTGGCC 
ATCAGGAGAA CAGTGCCCCC CATGGTGAAT GTCACCTGCA GCGAGGTCTC AGAGGGCAAC 
ATCACCGTGA CATGCAGGGC TTCCAGCTTC TATCCCCGGA ATATCACACT GACCTGGCGT 
CAGGATGGGG TATCTTTGAG CCACAACACC CAGCAGTGGG GGGATGTCCT GCCTGATGGG 
AATGGAACCT ACCAGACCTG GGTGGCCACC AGGATTCGCC AAGGAGAGGA GCAGAGGTTC 
ACCTGCTACA TGGAACACAG CGGGAATCAC GGCACTCACC CTGTGCCCTC TGGGAAGGCG 
CTGGTGCTTC AGAGTCAACG GACAGACTTT CCATATGTTT CTGCTGCTAT GCCATGTTTT 
GTTATTATTA TTATTCTCTG TGTCCCTTGT TGCAAGAAGA AAACATCAGC GGCAGAGGGT 
CCAGAGCTTG TGAGCCTGCA GGTCCTGGAT CAACACCCAG TTGGGACAGG AGACCACAGG 
GATGCAGCAC AGCTGGGATT TCAGCCTCTG ATGTCAGCTA CTGGGTCCAC TGGTTCCACT 
GAGGGCACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005922.2
CDS	50..1201
Translation	MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGT

Target ORF information:

RefSeq Version	NM_005931.5
Organism	Homo sapiens(human)
Definition	Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005931.5

ORF Insert Sequence:

ATGGGGCTGG GCCGGGTCCT GCTGTTTCTG GCCGTCGCCT TCCCTTTTGC ACCCCCGGCA 
GCCGCCGCTG AGCCCCACAG TCTTCGTTAC AACCTCATGG TGCTGTCCCA GGATGGATCT 
GTGCAGTCAG GGTTTCTCGC TGAGGGACAT CTGGATGGTC AGCCCTTCCT GCGCTATGAC 
AGGCAGAAAC GCAGGGCAAA GCCCCAGGGA CAGTGGGCAG AAAATGTCCT GGGAGCTAAG 
ACCTGGGACA CAGAGACCGA GGACTTGACA GAGAATGGGC AAGACCTCAG GAGGACCCTG 
ACTCATATCA AGGACCAGAA AGGAGGCTTG CATTCCCTCC AGGAGATTAG GGTCTGTGAG 
ATCCATGAAG ACAGCAGCAC CAGGGGCTCC CGGCATTTCT ACTACGATGG GGAGCTCTTC 
CTCTCCCAAA ACCTGGAGAC TCAAGAATCG ACAGTGCCCC AGTCCTCCAG AGCTCAGACC 
TTGGCTATGA ACGTCACAAA TTTCTGGAAG GAAGATGCCA TGAAGACCAA GACACACTAT 
CGCGCTATGC AGGCAGACTG CCTGCAGAAA CTACAGCGAT ATCTGAAATC CGGGGTGGCC 
ATCAGGAGAA CAGTGCCCCC CATGGTGAAT GTCACCTGCA GCGAGGTCTC AGAGGGCAAC 
ATCACCGTGA CATGCAGGGC TTCCAGCTTC TATCCCCGGA ATATCACACT GACCTGGCGT 
CAGGATGGGG TATCTTTGAG CCACAACACC CAGCAGTGGG GGGATGTCCT GCCTGATGGG 
AATGGAACCT ACCAGACCTG GGTGGCCACC AGGATTCGCC AAGGAGAGGA GCAGAGGTTC 
ACCTGCTACA TGGAACACAG CGGGAATCAC GGCACTCACC CTGTGCCCTC TGGGAAGGCG 
CTGGTGCTTC AGAGTCAACG GACAGACTTT CCATATGTTT CTGCTGCTAT GCCATGTTTT 
GTTATTATTA TTATTCTCTG TGTCCCTTGT TGCAAGAAGA AAACATCAGC GGCAGAGGGT 
CCAGAGCTTG TGAGCCTGCA GGTCCTGGAT CAACACCCAG TTGGGACAGG AGACCACAGG 
GATGCAGCAC AGCTGGGATT TCAGCCTCTG ATGTCAGCTA CTGGGTCCAC TGGTTCCACT 
GAGGGCACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Diversity and characterisation of polymorphic 3' untranslated region haplotypes of MICA and MICB genes.
HLA92(6)392-402(2018 12)
Cox ST,Hernandez D,Danby R,Turner TR,Madrigal JA

MicroRNA-34a promotes MICB expression in hepatocytes.
Carcinogenesis39(12)1477-1487(2018 12)
Zhou MT,Zhao C,Chen X,Zhang HC,Li G,Lou H,Huang WJ,Wei LJ,Li DW,Wu X,Zhang ZC,Liu H,Ou R,Yang WJ,Hu S,Xu Y,Tang KF

Genetic polymorphism analysis of MICB gene in Jing ethnic minority of Southern China.
HLA92(4)224-230(2018 10)
Liu X,Chen X,Wei X,Meng Y,Liu L,Dai S

Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis.
BMC infectious diseases18(1)282(2018 06)
Cahill ME,Conley S,DeWan AT,Montgomery RR

Association of MICA and MICB polymorphisms with the susceptibility of leukemia in Korean patients.
Blood cancer journal8(6)58(2018 06)
Baek IC,Shin DH,Choi EJ,Kim HJ,Yoon JH,Cho BS,Kim YJ,Lee S,Min WS,Kim HJ,Kim TG

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MICB cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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