MCM5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MCM5
Entrez Gene ID	4174
Full Name	minichromosome maintenance complex component 5
Synonyms	CDC46,MGORS8,P1-CDC46
General protein information	Preferred Names minichromosome maintenance complex component 5 Names DNA replication licensing factor MCM5 CDC46 homolog MCM5 minichromosome maintenance deficient 5, cell division cycle 46 minichromosome maintenance deficient 5 (cell division cycle 46)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q12.3
Summary	The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008].
Disorder MIM:	602696
Disorder Html:	?Meier-Gorlin syndrome 8, 617564 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006739.4	NP_006730.2	DNA replication licensing factor MCM5
XM_006724242.3	XP_006724305.1	DNA replication licensing factor MCM5 isoform X1
XM_006724242.4	XP_006724305.1	DNA replication licensing factor MCM5 isoform X1
NM_006739.3	NP_006730.2	DNA replication licensing factor MCM5

Pathways from BioSystems

Homologies

Homo sapiens (human)	MCM5	NP_006730.2
Rattus norvegicus (Norway rat)	Mcm5	NP_001099640.1
Oryza sativa (rice)	Os02g0797400	NP_001048396.1
Pan troglodytes (chimpanzee)	MCM5	XP_001156025.1
Canis lupus familiaris (dog)	MCM5	XP_005626282.1
Caenorhabditis elegans (roundworm)	mcm-5	NP_497858.1
Saccharomyces cerevisiae (baker's yeast)	MCM5	NP_013376.1
Xenopus tropicalis (tropical clawed frog)	mcm5	NP_001017327.2
Neurospora crassa	NCU01171	XP_961537.1
Kluyveromyces lactis	KLLA0D09262g	XP_453475.1
Schizosaccharomyces pombe (fission yeast)	mcm5	XP_001713071.1
Bos taurus (cattle)	MCM5	NP_001068758.1
Mus musculus (house mouse)	Mcm5	NP_032592.2
Gallus gallus (chicken)	MCM5	NP_001006243.1
Drosophila melanogaster (fruit fly)	Mcm5	NP_524308.2
Danio rerio (zebrafish)	mcm5	NP_848523.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004408	XP_313694.2
Magnaporthe oryzae (rice blast fungus)	MGG_08646	XP_003711077.1
Eremothecium gossypii	AGOS_AGR276W	NP_986942.1
Arabidopsis thaliana (thale cress)	MCM5	NP_178812.1

Gene Ontology
Bibliography

Related articles in PubMed

MCM5 Expression Is Associated With the Grade of Malignancy and Ki-67 Antigen in LSCC.
Nowinska K, Ciesielska U, Piotrowska A, Jablonska K, Partynska A, Paprocka M, Zatonski T, Podhorska-Okolow M, Dziegiel P
Anticancer research39(5)2325-2335(2019 May)

Minichromosome Maintenance Proteins MCM-3, MCM-5, MCM-7, and Ki-67 as Proliferative Markers in Adrenocortical Tumors.
Aporowicz M, Czopnik P, Kubicka E, Piotrowska A, Dziegiel P, Bolanowski M, Domoslawski P
Anticancer research39(3)1151-1159(2019 Mar)

Comparative Study of the Minichromosome Maintenance Proteins Complex (MCM 4/5/6) in Ameloblastoma and Unicystic Ameloblastoma.
Apellániz D, Pereira-Prado V, Sicco E, Vigil-Bastitta G, González-González R, Mosqueda-Taylor A, Molina-Frechero N, Hernandez M, Sánchez-Romero C, Bologna-Molina R
International journal of surgical pathology26(8)714-720(2018 Dec)

MiR-362-3p functions as a tumor suppressor through targeting MCM5 in cervical adenocarcinoma.
Wang D, Wang H, Li Y, Li Q
Bioscience reports38(3)(2018 06)

Identification of Significant Gene Signatures and Prognostic Biomarkers for Patients With Cervical Cancer by Integrated Bioinformatic Methods.
Li X, Tian R, Gao H, Yan F, Ying L, Yang Y, Yang P, Gao Y
Technology in cancer research & treatment171533033818767455(2018 01)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MCM5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MCM5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu53579	XM_006724242.4 Latest version!	Homo sapiens minichromosome maintenance complex component 5 (MCM5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu02170	NM_006739.4 Latest version!	Homo sapiens minichromosome maintenance complex component 5 (MCM5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu53579	XM_006724242.3	Homo sapiens minichromosome maintenance complex component 5 (MCM5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu02170	NM_006739.3	Homo sapiens minichromosome maintenance complex component 5 (MCM5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MCM5 ( XM_006724242.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006724305.1 Homo sapiens minichromosome maintenance complex component 5 (MCM5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu53579
Clone ID Related Accession (Same CDS sequence)	XM_006724242.3 , XM_006724242.4
Accession Version	XM_006724242.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	DNA replication licensing factor MCM5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006724242.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGCTCTCCC TCCTGTCAGG ACAAGCAAAA GCATCAGAGA CAGAGACAGA CAGAGATAGA 
GATGAAAGAC AGACAGAGTT GGAGACGGCG ATAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006724305.1
CDS	150..2348
Translation	MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQLSLLSGQAKASETETDRDRDERQTELETAIE

Target ORF information:

RefSeq Version	XM_006724242.3
Organism	Homo sapiens(human)
Definition	Homo sapiens minichromosome maintenance complex component 5 (MCM5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006724242.3

ORF Insert Sequence:

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGCTCTCCC TCCTGTCAGG ACAAGCAAAA GCATCAGAGA CAGAGACAGA CAGAGATAGA 
GATGAAAGAC AGACAGAGTT GGAGACGGCG ATAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MCM5 ( XM_006724242.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006724305.1 Homo sapiens minichromosome maintenance complex component 5 (MCM5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu53579
Clone ID Related Accession (Same CDS sequence)	XM_006724242.3 , XM_006724242.4
Accession Version	XM_006724242.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	DNA replication licensing factor MCM5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006724242.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGCTCTCCC TCCTGTCAGG ACAAGCAAAA GCATCAGAGA CAGAGACAGA CAGAGATAGA 
GATGAAAGAC AGACAGAGTT GGAGACGGCG ATAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006724305.1
CDS	85..2283
Translation	MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQLSLLSGQAKASETETDRDRDERQTELETAIE

Target ORF information:

RefSeq Version	XM_006724242.4
Organism	Homo sapiens(human)
Definition	Homo sapiens minichromosome maintenance complex component 5 (MCM5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006724242.4

ORF Insert Sequence:

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGCTCTCCC TCCTGTCAGG ACAAGCAAAA GCATCAGAGA CAGAGACAGA CAGAGATAGA 
GATGAAAGAC AGACAGAGTT GGAGACGGCG ATAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MCM5 ( NM_006739.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006730.2 Homo sapiens minichromosome maintenance complex component 5 (MCM5), mRNA.

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CloneID	OHu02170
Clone ID Related Accession (Same CDS sequence)	NM_006739.4 , NM_006739.3
Accession Version	NM_006739.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1558886400000
Organism	Homo sapiens(human)
Product	DNA replication licensing factor MCM5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM787690.1, X74795.2 and Z82244.1. On Nov 22, 2018 this sequence version replaced NM_006739.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.22654.1, SRR1803614.45180.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000216122.9/ ENSP00000216122.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGAAATACC CGGAGCACGC CATCCACAAG GTGCTGCAGC TCATGCTGCG GCGCGGCGAG 
ATCCAGCATC GCATGCAGCG CAAGGTTCTC TACCGCCTCA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006730.2
CDS	78..2282
Translation	MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK

Target ORF information:

RefSeq Version	NM_006739.4
Organism	Homo sapiens(human)
Definition	Homo sapiens minichromosome maintenance complex component 5 (MCM5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006739.4

ORF Insert Sequence:

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGAAATACC CGGAGCACGC CATCCACAAG GTGCTGCAGC TCATGCTGCG GCGCGGCGAG 
ATCCAGCATC GCATGCAGCG CAAGGTTCTC TACCGCCTCA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MCM5 ( NM_006739.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006730.2 Homo sapiens minichromosome maintenance complex component 5 (MCM5), mRNA.

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CloneID	OHu02170
Clone ID Related Accession (Same CDS sequence)	NM_006739.4 , NM_006739.3
Accession Version	NM_006739.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1510416000000
Organism	Homo sapiens(human)
Product	DNA replication licensing factor MCM5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM787690.1 and X74795.2. On Apr 6, 2007 this sequence version replaced NM_006739.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.30465.1, SRR1803611.103811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGAAATACC CGGAGCACGC CATCCACAAG GTGCTGCAGC TCATGCTGCG GCGCGGCGAG 
ATCCAGCATC GCATGCAGCG CAAGGTTCTC TACCGCCTCA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006730.2
CDS	95..2299
Translation	MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK

Target ORF information:

RefSeq Version	NM_006739.3
Organism	Homo sapiens(human)
Definition	Homo sapiens minichromosome maintenance complex component 5 (MCM5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006739.3

ORF Insert Sequence:

ATGTCGGGAT TCGACGATCC TGGCATTTTC TACAGCGACA GCTTCGGGGG CGACGCCCAG 
GCCGACGAGG GGCAGGCCCG CAAATCGCAG CTGCAGAGGC GCTTCAAGGA GTTCCTGCGG 
CAGTACCGAG TGGGCACCGA CCGCACGGGC TTCACCTTCA AATACAGGGA TGAACTCAAG 
CGGCATTACA ACCTGGGGGA GTACTGGATT GAGGTGGAGA TGGAGGATCT GGCCAGCTTT 
GATGAGGACC TGGCCGACTA CTTGTACAAG CAGCCAGCCG AGCACCTGCA GCTGCTGGAG 
GAAGCTGCCA AGGAGGTAGC TGATGAGGTG ACCCGGCCCC GGCCTTCTGG GGAGGAGGTG 
CTCCAGGACA TCCAGGTCAT GCTCAAGTCG GACGCCAGCC CTTCCAGCAT TCGTAGCCTG 
AAGTCGGACA TGATGTCACA CCTGGTGAAG ATCCCTGGCA TCATCATCGC GGCCTCTGCG 
GTCCGTGCCA AGGCCACCCG CATCTCTATC CAGTGCCGCA GCTGCCGCAA CACCCTCACC 
AACATTGCCA TGCGCCCTGG CCTCGAGGGC TATGCCCTGC CCAGGAAGTG CAACACAGAT 
CAGGCTGGGC GCCCCAAATG CCCATTGGAC CCGTACTTCA TCATGCCCGA CAAATGCAAA 
TGCGTGGACT TCCAGACCCT GAAGCTGCAG GAGCTGCCTG ATGCAGTCCC CCACGGGGAG 
ATGCCCAGAC ACATGCAGCT CTACTGCGAC AGGTACCTGT GTGACAAGGT CGTCCCTGGG 
AACAGGGTTA CCATCATGGG CATCTACTCC ATCAAGAAGT TTGGCCTGAC TACCAGCAGG 
GGCCGTGACA GGGTGGGCGT GGGCATCCGA AGCTCCTACA TCCGTGTCCT GGGCATCCAG 
GTGGACACAG ATGGCTCTGG CCGCAGCTTT GCTGGGGCCG TGAGCCCCCA GGAGGAGGAG 
GAGTTCCGTC GCCTGGCTGC CCTCCCAAAT GTCTATGAGG TCATCTCCAA GAGCATCGCC 
CCCTCCATCT TTGGGGGCAC AGACATGAAG AAGGCCATTG CCTGCCTGCT CTTTGGGGGC 
TCCCGAAAGA GGCTCCCTGA TGGACTTACT CGCCGAGGAG ACATCAACCT GCTGATGCTA 
GGGGACCCTG GGACAGCCAA GTCCCAGCTT CTGAAGTTTG TGGAGAAGTG TTCTCCCATT 
GGGGTATACA CGTCTGGGAA AGGCAGCAGC GCAGCTGGAC TGACAGCCTC GGTGATGAGG 
GACCCTTCGT CCCGGAATTT CATCATGGAG GGCGGAGCCA TGGTCCTGGC CGATGGTGGG 
GTCGTCTGTA TTGACGAGTT TGACAAGATG CGAGAAGATG ACCGTGTGGC AATCCACGAA 
GCCATGGAGC AGCAGACCAT CTCTATCGCC AAGGCTGGGA TCACCACCAC CCTGAACTCC 
CGCTGCTCCG TCCTGGCTGC TGCCAACTCA GTGTTCGGCC GCTGGGATGA GACGAAGGGG 
GAGGACAACA TTGACTTCAT GCCCACCATC TTGTCGCGCT TCGACATGAT CTTCATCGTC 
AAGGATGAGC ACAATGAGGA GAGGGATGTG ATGCTGGCCA AGCATGTCAT CACTCTGCAC 
GTGAGCGCAC TGACACAGAC ACAGGCTGTG GAGGGCGAGA TTGACCTGGC CAAGCTGAAG 
AAGTTTATTG CCTACTGCCG AGTGAAGTGT GGCCCCCGGC TGTCAGCAGA GGCTGCAGAG 
AAACTGAAGA ACCGCTACAT CATCATGCGG AGCGGGGCCC GTCAGCACGA GAGGGACAGT 
GACCGCCGCT CCAGCATCCC CATCACTGTG CGGCAGCTGG AGGCCATTGT GCGCATCGCG 
GAAGCCCTCA GCAAGATGAA GCTGCAGCCC TTCGCCACAG AGGCAGATGT GGAGGAGGCC 
CTGCGGCTCT TCCAAGTGTC CACGTTGGAT GCTGCCTTGT CCGGTACCCT GTCAGGGGTG 
GAGGGCTTCA CCAGCCAGGA GGACCAGGAG ATGCTGAGCC GCATCGAGAA GCAGCTCAAG 
CGCCGCTTTG CCATTGGCTC CCAGGTGTCT GAGCACAGCA TCATCAAGGA CTTCACCAAG 
CAGAAATACC CGGAGCACGC CATCCACAAG GTGCTGCAGC TCATGCTGCG GCGCGGCGAG 
ATCCAGCATC GCATGCAGCG CAAGGTTCTC TACCGCCTCA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MCM5 Expression Is Associated With the Grade of Malignancy and Ki-67 Antigen in LSCC.
Anticancer research39(5)2325-2335(2019 May)
Nowinska K,Ciesielska U,Piotrowska A,Jablonska K,Partynska A,Paprocka M,Zatonski T,Podhorska-Okolow M,Dziegiel P

Minichromosome Maintenance Proteins MCM-3, MCM-5, MCM-7, and Ki-67 as Proliferative Markers in Adrenocortical Tumors.
Anticancer research39(3)1151-1159(2019 Mar)
Aporowicz M,Czopnik P,Kubicka E,Piotrowska A,Dziegiel P,Bolanowski M,Domoslawski P

Comparative Study of the Minichromosome Maintenance Proteins Complex (MCM 4/5/6) in Ameloblastoma and Unicystic Ameloblastoma.
International journal of surgical pathology26(8)714-720(2018 Dec)
Apellániz D,Pereira-Prado V,Sicco E,Vigil-Bastitta G,González-González R,Mosqueda-Taylor A,Molina-Frechero N,Hernandez M,Sánchez-Romero C,Bologna-Molina R

MiR-362-3p functions as a tumor suppressor through targeting MCM5 in cervical adenocarcinoma.
Bioscience reports38(3)(2018 06)
Wang D,Wang H,Li Y,Li Q

Identification of Significant Gene Signatures and Prognostic Biomarkers for Patients With Cervical Cancer by Integrated Bioinformatic Methods.
Technology in cancer research & treatment171533033818767455(2018 01)
Li X,Tian R,Gao H,Yan F,Ying L,Yang Y,Yang P,Gao Y

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MCM5 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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