| Gene Symbol | IRF3 |
| Entrez Gene ID | 3661 |
| Full Name | interferon regulatory factor 3 |
| Synonyms | IIAE7 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]. |
| Disorder MIM: | |
| Disorder Html: | {?Herpes simplex encephalitis, susceptibility to, 7}, 616532 (3) |

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