| Gene Symbol | ILK |
| Entrez Gene ID | 3611 |
| Full Name | integrin linked kinase |
| Synonyms | HEL-S-28,ILK-1,ILK-2,P59,p59ILK |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]. |
| Disorder MIM: |
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