SLC10A6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC10A6
Entrez Gene ID	345274
Full Name	solute carrier family 10 member 6
Synonyms	SOAT
General protein information	Preferred Names solute carrier family 10 member 6 Names solute carrier family 10 member 6 sodium-dependent organic anion transporter solute carrier family 10 (sodium/bile acid cotransporter family), member 6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q21.3
Disorder MIM:	613366

mRNA and Protein(s)

mRNA	Protein	Name
NM_197965.2	NP_932069.1	solute carrier family 10 member 6
NM_197965.3	NP_932069.1	solute carrier family 10 member 6

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	slc10a6	XP_002936511.1
Bos taurus (cattle)	SLC10A6	NP_001075207.1
Homo sapiens (human)	SLC10A6	NP_932069.1
Macaca mulatta (Rhesus monkey)	SLC10A6	XP_001092284.2
Pan troglodytes (chimpanzee)	SLC10A6	XP_526626.2
Canis lupus familiaris (dog)	SLC10A6	XP_005639206.1
Mus musculus (house mouse)	Slc10a6	NP_083691.1
Rattus norvegicus (Norway rat)	Slc10a6	NP_932166.1

Gene Ontology
Bibliography

Related articles in PubMed

Transport of steroid 3-sulfates and steroid 17-sulfates by the sodium-dependent organic anion transporter SOAT (SLC10A6).
Grosser G, Bennien J, Sánchez-Guijo A, Bakhaus K, Döring B, Hartmann M, Wudy SA, Geyer J
The Journal of steroid biochemistry and molecular biology17920-25(2018 05)

The polymorphism L204F affects transport and membrane expression of the sodium-dependent organic anion transporter SOAT (SLC10A6).
Bakhaus K, Fietz D, Kliesch S, Weidner W, Bergmann M, Geyer J
The Journal of steroid biochemistry and molecular biology17936-44(2018 05)

Rare genetic variants in the sodium-dependent organic anion transporter SOAT (SLC10A6): Effects on transport function and membrane expression.
Bennien J, Fischer T, Geyer J
The Journal of steroid biochemistry and molecular biology17926-35(2018 05)

Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.
Chen G, Bentley A, Adeyemo A, Shriner D, Zhou J, Doumatey A, Huang H, Ramos E, Erdos M, Gerry N, Herbert A, Christman M, Rotimi C
Human molecular genetics21(20)4530-6(2012 Oct)

Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6).
Geyer J, Döring B, Meerkamp K, Ugele B, Bakhiya N, Fernandes CF, Godoy JR, Glatt H, Petzinger E
The Journal of biological chemistry282(27)19728-41(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SLC10A6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC10A6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02447	NM_197965.3 Latest version!	Homo sapiens solute carrier family 10 member 6 (SLC10A6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu02447	NM_197965.2	Homo sapiens solute carrier family 10 member 6 (SLC10A6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC10A6 ( NM_197965.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_932069.1 Homo sapiens solute carrier family 10 member 6 (SLC10A6), mRNA.

Price & Availability↑

CloneID	OHu02447
Clone ID Related Accession (Same CDS sequence)	NM_197965.2 , NM_197965.3
Accession Version	NM_197965.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550592000000
Organism	Homo sapiens(human)
Product	solute carrier family 10 member 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EF437223.1. On Mar 24, 2009 this sequence version replaced NM_197965.1. ##Evidence-Data-START## Transcript exon combination :: EF437223.1, SRR1803616.309206.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END##

ATGAGAGCCA ATTGTTCCAG CAGCTCAGCC TGCCCTGCCA ACAGTTCAGA GGAGGAGCTG 
CCAGTGGGAC TGGAGGTGCA TGGAAACCTG GAGCTCGTTT TCACAGTGGT GTCCACTGTG 
ATGATGGGGC TGCTCATGTT CTCTTTGGGA TGTTCCGTGG AGATCCGGAA GCTGTGGTCG 
CACATCAGGA GACCCTGGGG CATTGCTGTG GGACTGCTCT GCCAGTTTGG GCTCATGCCT 
TTTACAGCTT ATCTCCTGGC CATTAGCTTT TCTCTGAAGC CAGTCCAAGC TATTGCTGTT 
CTCATCATGG GCTGCTGCCC GGGGGGCACC ATCTCTAACA TTTTCACCTT CTGGGTTGAT 
GGAGATATGG ATCTCAGCAT CAGTATGACA ACCTGTTCCA CCGTGGCCGC CCTGGGAATG 
ATGCCACTCT GCATTTATCT CTACACCTGG TCCTGGAGTC TTCAGCAGAA TCTCACCATT 
CCTTATCAGA ACATAGGAAT TACCCTTGTG TGCCTGACCA TTCCTGTGGC CTTTGGTGTC 
TATGTGAATT ACAGATGGCC AAAACAATCC AAAATCATTC TCAAGATTGG GGCCGTTGTT 
GGTGGGGTCC TCCTTCTGGT GGTCGCAGTT GCTGGTGTGG TCCTGGCGAA AGGATCTTGG 
AATTCAGACA TCACCCTTCT GACCATCAGT TTCATCTTTC CTTTGATTGG CCATGTCACG 
GGTTTTCTGC TGGCACTTTT TACCCACCAG TCTTGGCAAA GGTGCAGGAC AATTTCCTTA 
GAAACTGGAG CTCAGAATAT TCAGATGTGC ATCACCATGC TCCAGTTATC TTTCACTGCT 
GAGCACTTGG TCCAGATGTT GAGTTTCCCA CTGGCCTATG GACTCTTCCA GCTGATAGAT 
GGATTTCTTA TTGTTGCAGC ATATCAGACG TACAAGAGGA GATTGAAGAA CAAACATGGA 
AAAAAGAACT CAGGTTGCAC AGAAGTCTGC CATACGAGGA AATCGACTTC TTCCAGAGAG 
ACCAATGCCT TCTTGGAGGT GAATGAAGAA GGTGCCATCA CTCCTGGGCC ACCAGGGCCA 
ATGGATTGCC ACAGGGCTCT CGAGCCAGTT GGCCACATCA CTTCATGTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_932069.1
CDS	149..1282
Translation	MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGPMDCHRALEPVGHITSCE

Target ORF information:

RefSeq Version	NM_197965.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 10 member 6 (SLC10A6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_197965.2

ORF Insert Sequence:

ATGAGAGCCA ATTGTTCCAG CAGCTCAGCC TGCCCTGCCA ACAGTTCAGA GGAGGAGCTG 
CCAGTGGGAC TGGAGGTGCA TGGAAACCTG GAGCTCGTTT TCACAGTGGT GTCCACTGTG 
ATGATGGGGC TGCTCATGTT CTCTTTGGGA TGTTCCGTGG AGATCCGGAA GCTGTGGTCG 
CACATCAGGA GACCCTGGGG CATTGCTGTG GGACTGCTCT GCCAGTTTGG GCTCATGCCT 
TTTACAGCTT ATCTCCTGGC CATTAGCTTT TCTCTGAAGC CAGTCCAAGC TATTGCTGTT 
CTCATCATGG GCTGCTGCCC GGGGGGCACC ATCTCTAACA TTTTCACCTT CTGGGTTGAT 
GGAGATATGG ATCTCAGCAT CAGTATGACA ACCTGTTCCA CCGTGGCCGC CCTGGGAATG 
ATGCCACTCT GCATTTATCT CTACACCTGG TCCTGGAGTC TTCAGCAGAA TCTCACCATT 
CCTTATCAGA ACATAGGAAT TACCCTTGTG TGCCTGACCA TTCCTGTGGC CTTTGGTGTC 
TATGTGAATT ACAGATGGCC AAAACAATCC AAAATCATTC TCAAGATTGG GGCCGTTGTT 
GGTGGGGTCC TCCTTCTGGT GGTCGCAGTT GCTGGTGTGG TCCTGGCGAA AGGATCTTGG 
AATTCAGACA TCACCCTTCT GACCATCAGT TTCATCTTTC CTTTGATTGG CCATGTCACG 
GGTTTTCTGC TGGCACTTTT TACCCACCAG TCTTGGCAAA GGTGCAGGAC AATTTCCTTA 
GAAACTGGAG CTCAGAATAT TCAGATGTGC ATCACCATGC TCCAGTTATC TTTCACTGCT 
GAGCACTTGG TCCAGATGTT GAGTTTCCCA CTGGCCTATG GACTCTTCCA GCTGATAGAT 
GGATTTCTTA TTGTTGCAGC ATATCAGACG TACAAGAGGA GATTGAAGAA CAAACATGGA 
AAAAAGAACT CAGGTTGCAC AGAAGTCTGC CATACGAGGA AATCGACTTC TTCCAGAGAG 
ACCAATGCCT TCTTGGAGGT GAATGAAGAA GGTGCCATCA CTCCTGGGCC ACCAGGGCCA 
ATGGATTGCC ACAGGGCTCT CGAGCCAGTT GGCCACATCA CTTCATGTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC10A6 ( NM_197965.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_932069.1 Homo sapiens solute carrier family 10 member 6 (SLC10A6), mRNA.

Price & Availability↑

CloneID	OHu02447
Clone ID Related Accession (Same CDS sequence)	NM_197965.2 , NM_197965.3
Accession Version	NM_197965.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	solute carrier family 10 member 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC093827.3 and EF437223.1. On May 17, 2019 this sequence version replaced NM_197965.2. ##Evidence-Data-START## Transcript exon combination :: EF437223.1, SRR1803616.309206.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000273905.7/ ENSP00000273905.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGAGCCA ATTGTTCCAG CAGCTCAGCC TGCCCTGCCA ACAGTTCAGA GGAGGAGCTG 
CCAGTGGGAC TGGAGGTGCA TGGAAACCTG GAGCTCGTTT TCACAGTGGT GTCCACTGTG 
ATGATGGGGC TGCTCATGTT CTCTTTGGGA TGTTCCGTGG AGATCCGGAA GCTGTGGTCG 
CACATCAGGA GACCCTGGGG CATTGCTGTG GGACTGCTCT GCCAGTTTGG GCTCATGCCT 
TTTACAGCTT ATCTCCTGGC CATTAGCTTT TCTCTGAAGC CAGTCCAAGC TATTGCTGTT 
CTCATCATGG GCTGCTGCCC GGGGGGCACC ATCTCTAACA TTTTCACCTT CTGGGTTGAT 
GGAGATATGG ATCTCAGCAT CAGTATGACA ACCTGTTCCA CCGTGGCCGC CCTGGGAATG 
ATGCCACTCT GCATTTATCT CTACACCTGG TCCTGGAGTC TTCAGCAGAA TCTCACCATT 
CCTTATCAGA ACATAGGAAT TACCCTTGTG TGCCTGACCA TTCCTGTGGC CTTTGGTGTC 
TATGTGAATT ACAGATGGCC AAAACAATCC AAAATCATTC TCAAGATTGG GGCCGTTGTT 
GGTGGGGTCC TCCTTCTGGT GGTCGCAGTT GCTGGTGTGG TCCTGGCGAA AGGATCTTGG 
AATTCAGACA TCACCCTTCT GACCATCAGT TTCATCTTTC CTTTGATTGG CCATGTCACG 
GGTTTTCTGC TGGCACTTTT TACCCACCAG TCTTGGCAAA GGTGCAGGAC AATTTCCTTA 
GAAACTGGAG CTCAGAATAT TCAGATGTGC ATCACCATGC TCCAGTTATC TTTCACTGCT 
GAGCACTTGG TCCAGATGTT GAGTTTCCCA CTGGCCTATG GACTCTTCCA GCTGATAGAT 
GGATTTCTTA TTGTTGCAGC ATATCAGACG TACAAGAGGA GATTGAAGAA CAAACATGGA 
AAAAAGAACT CAGGTTGCAC AGAAGTCTGC CATACGAGGA AATCGACTTC TTCCAGAGAG 
ACCAATGCCT TCTTGGAGGT GAATGAAGAA GGTGCCATCA CTCCTGGGCC ACCAGGGCCA 
ATGGATTGCC ACAGGGCTCT CGAGCCAGTT GGCCACATCA CTTCATGTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_932069.1
CDS	270..1403
Translation	MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGPMDCHRALEPVGHITSCE

Target ORF information:

RefSeq Version	NM_197965.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 10 member 6 (SLC10A6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_197965.3

ORF Insert Sequence:

ATGAGAGCCA ATTGTTCCAG CAGCTCAGCC TGCCCTGCCA ACAGTTCAGA GGAGGAGCTG 
CCAGTGGGAC TGGAGGTGCA TGGAAACCTG GAGCTCGTTT TCACAGTGGT GTCCACTGTG 
ATGATGGGGC TGCTCATGTT CTCTTTGGGA TGTTCCGTGG AGATCCGGAA GCTGTGGTCG 
CACATCAGGA GACCCTGGGG CATTGCTGTG GGACTGCTCT GCCAGTTTGG GCTCATGCCT 
TTTACAGCTT ATCTCCTGGC CATTAGCTTT TCTCTGAAGC CAGTCCAAGC TATTGCTGTT 
CTCATCATGG GCTGCTGCCC GGGGGGCACC ATCTCTAACA TTTTCACCTT CTGGGTTGAT 
GGAGATATGG ATCTCAGCAT CAGTATGACA ACCTGTTCCA CCGTGGCCGC CCTGGGAATG 
ATGCCACTCT GCATTTATCT CTACACCTGG TCCTGGAGTC TTCAGCAGAA TCTCACCATT 
CCTTATCAGA ACATAGGAAT TACCCTTGTG TGCCTGACCA TTCCTGTGGC CTTTGGTGTC 
TATGTGAATT ACAGATGGCC AAAACAATCC AAAATCATTC TCAAGATTGG GGCCGTTGTT 
GGTGGGGTCC TCCTTCTGGT GGTCGCAGTT GCTGGTGTGG TCCTGGCGAA AGGATCTTGG 
AATTCAGACA TCACCCTTCT GACCATCAGT TTCATCTTTC CTTTGATTGG CCATGTCACG 
GGTTTTCTGC TGGCACTTTT TACCCACCAG TCTTGGCAAA GGTGCAGGAC AATTTCCTTA 
GAAACTGGAG CTCAGAATAT TCAGATGTGC ATCACCATGC TCCAGTTATC TTTCACTGCT 
GAGCACTTGG TCCAGATGTT GAGTTTCCCA CTGGCCTATG GACTCTTCCA GCTGATAGAT 
GGATTTCTTA TTGTTGCAGC ATATCAGACG TACAAGAGGA GATTGAAGAA CAAACATGGA 
AAAAAGAACT CAGGTTGCAC AGAAGTCTGC CATACGAGGA AATCGACTTC TTCCAGAGAG 
ACCAATGCCT TCTTGGAGGT GAATGAAGAA GGTGCCATCA CTCCTGGGCC ACCAGGGCCA 
ATGGATTGCC ACAGGGCTCT CGAGCCAGTT GGCCACATCA CTTCATGTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transport of steroid 3-sulfates and steroid 17-sulfates by the sodium-dependent organic anion transporter SOAT (SLC10A6).
The Journal of steroid biochemistry and molecular biology17920-25(2018 05)
Grosser G,Bennien J,Sánchez-Guijo A,Bakhaus K,Döring B,Hartmann M,Wudy SA,Geyer J

The polymorphism L204F affects transport and membrane expression of the sodium-dependent organic anion transporter SOAT (SLC10A6).
The Journal of steroid biochemistry and molecular biology17936-44(2018 05)
Bakhaus K,Fietz D,Kliesch S,Weidner W,Bergmann M,Geyer J

Rare genetic variants in the sodium-dependent organic anion transporter SOAT (SLC10A6): Effects on transport function and membrane expression.
The Journal of steroid biochemistry and molecular biology17926-35(2018 05)
Bennien J,Fischer T,Geyer J

Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.
Human molecular genetics21(20)4530-6(2012 Oct)
Chen G,Bentley A,Adeyemo A,Shriner D,Zhou J,Doumatey A,Huang H,Ramos E,Erdos M,Gerry N,Herbert A,Christman M,Rotimi C

Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6).
The Journal of biological chemistry282(27)19728-41(2007 Jul)
Geyer J,Döring B,Meerkamp K,Ugele B,Bakhiya N,Fernandes CF,Godoy JR,Glatt H,Petzinger E

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SLC10A6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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