ARHGEF26 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ARHGEF26
Entrez Gene ID	26084
Full Name	Rho guanine nucleotide exchange factor 26
Synonyms	CSGEF,HMFN1864,SGEF
General protein information	Preferred Names Rho guanine nucleotide exchange factor 26 Names rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor (GEF) 26 SH3 domain-containing guanine exchange factor Src homology 3 domain-containing guanine nucleotide exchange factor testicular tissue protein Li 171
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q25.2
Summary	This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011].
Disorder MIM:	617552

mRNA and Protein(s)

mRNA	Protein	Name
XM_017006160.1	XP_016861649.1	rho guanine nucleotide exchange factor 26 isoform X2
NM_001251963.2	NP_001238892.1	rho guanine nucleotide exchange factor 26 isoform 2
NM_015595.3	NP_056410.3	rho guanine nucleotide exchange factor 26 isoform 1
NM_001251962.1	NP_001238891.1	rho guanine nucleotide exchange factor 26 isoform 1
NM_001251963.1	NP_001238892.1	rho guanine nucleotide exchange factor 26 isoform 2
XM_011512672.1	XP_011510974.1	rho guanine nucleotide exchange factor 26 isoform X1
NM_015595.4	NP_056410.3	rho guanine nucleotide exchange factor 26 isoform 1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LOC708205	XP_002803053.1
Gallus gallus (chicken)	ARHGEF26	XP_426718.3
Bos taurus (cattle)	ARHGEF26	NP_001192918.1
Mus musculus (house mouse)	Arhgef26	NP_001074764.1
Xenopus tropicalis (tropical clawed frog)	arhgef26	XP_002933294.2
Canis lupus familiaris (dog)	ARHGEF26	XP_005634713.1
Homo sapiens (human)	ARHGEF26	NP_056410.3
Rattus norvegicus (Norway rat)	Arhgef26	XP_227201.4
Pan troglodytes (chimpanzee)	ARHGEF26	XP_526354.3

Gene Ontology
Bibliography

Related articles in PubMed

SGEF is a potential prognostic and therapeutic target for lung adenocarcinoma.
Chen Q, Lu X, Liu QX, Zhou D, Qiu Y, Dai JG, Zheng H
World journal of surgical oncology16(1)32(2018 Feb)

Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.
Klarin D, Zhu QM, Emdin CA, Chaffin M, Horner S, McMillan BJ, Leed A, Weale ME, Spencer CCA, Aguet F, Segrè AV, Ardlie KG, Khera AV, Kaushik VK, Natarajan P, , Kathiresan S
Nature genetics49(9)1392-1397(2017 Sep)

A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells.
Goicoechea SM, Zinn A, Awadia SS, Snyder K, Garcia-Mata R
Journal of cell science130(6)1064-1077(2017 03)

SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.
Ensign SP, Roos A, Mathews IT, Dhruv HD, Tuncali S, Sarkaria JN, Symons MH, Loftus JC, Berens ME, Tran NL
Molecular cancer research : MCR14(3)302-12(2016 Mar)

Tyrosine Phosphorylation of SGEF Regulates RhoG Activity and Cell Migration.
Okuyama Y, Umeda K, Negishi M, Katoh H
PloS one11(7)e0159617(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ARHGEF26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARHGEF26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10796	NM_001251962.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu10796	NM_015595.4 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu15440	NM_001251963.2 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu66786	XM_011512672.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu94056	XM_017006160.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu15440	NM_001251963.1	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu10796	NM_015595.3	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ARHGEF26 ( NM_015595.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056410.3 Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 2, mRNA.

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CloneID	OHu10796
Clone ID Related Accession (Same CDS sequence)	NM_015595.3 , NM_001251962.1 , NM_015595.4
Accession Version	NM_015595.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2616bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514217600000
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 26 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA248533.1, DB069290.1, AY552599.1 and AC018452.11. This sequence is a reference standard in the RefSeqGene project. On Jul 26, 2008 this sequence version replaced NM_015595.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM005484.1, BC078655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTCA CTGACCCAGG TGGAAATCGT TAGGTCATTT 
ACTGCTAAGC AGCCAGATGA ACTCTCCCTG CAGGTGGCTG ACGTCGTCCT CATCTATCAA 
CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA CGACTACGAG ATGGAGAAAG AGGCTGGTTT 
CCTATGGAAT GTGCCAAGGA GATAACATGT CAAGCTACAA TTGATAAGAA TGTGGAGAGA 
ATGGGACGCT TGCTAGGACT GGAGACCAAC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056410.3
CDS	212..2827
Translation	MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV

Target ORF information:

RefSeq Version	NM_015595.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015595.3

ORF Insert Sequence:

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTCA CTGACCCAGG TGGAAATCGT TAGGTCATTT 
ACTGCTAAGC AGCCAGATGA ACTCTCCCTG CAGGTGGCTG ACGTCGTCCT CATCTATCAA 
CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA CGACTACGAG ATGGAGAAAG AGGCTGGTTT 
CCTATGGAAT GTGCCAAGGA GATAACATGT CAAGCTACAA TTGATAAGAA TGTGGAGAGA 
ATGGGACGCT TGCTAGGACT GGAGACCAAC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF26 ( NM_001251962.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238891.1 Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10796
Clone ID Related Accession (Same CDS sequence)	NM_015595.3 , NM_001251962.1 , NM_015595.4
Accession Version	NM_001251962.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2616bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 26 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK127282.1, AC018452.11 and AY552599.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK127282.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2153932 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTCA CTGACCCAGG TGGAAATCGT TAGGTCATTT 
ACTGCTAAGC AGCCAGATGA ACTCTCCCTG CAGGTGGCTG ACGTCGTCCT CATCTATCAA 
CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA CGACTACGAG ATGGAGAAAG AGGCTGGTTT 
CCTATGGAAT GTGCCAAGGA GATAACATGT CAAGCTACAA TTGATAAGAA TGTGGAGAGA 
ATGGGACGCT TGCTAGGACT GGAGACCAAC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238891.1
CDS	285..2900
Translation	MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV

Target ORF information:

RefSeq Version	NM_001251962.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251962.1

ORF Insert Sequence:

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTCA CTGACCCAGG TGGAAATCGT TAGGTCATTT 
ACTGCTAAGC AGCCAGATGA ACTCTCCCTG CAGGTGGCTG ACGTCGTCCT CATCTATCAA 
CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA CGACTACGAG ATGGAGAAAG AGGCTGGTTT 
CCTATGGAAT GTGCCAAGGA GATAACATGT CAAGCTACAA TTGATAAGAA TGTGGAGAGA 
ATGGGACGCT TGCTAGGACT GGAGACCAAC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF26 ( NM_015595.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056410.3 Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 2, mRNA.

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CloneID	OHu10796
Clone ID Related Accession (Same CDS sequence)	NM_015595.3 , NM_001251962.1 , NM_015595.4
Accession Version	NM_015595.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2616bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566316800000
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 26 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA248533.1, DB069290.1, AY552599.1 and AC018452.11. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_015595.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC078655.1, AF415175.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000465093.6/ ENSP00000423418.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTCA CTGACCCAGG TGGAAATCGT TAGGTCATTT 
ACTGCTAAGC AGCCAGATGA ACTCTCCCTG CAGGTGGCTG ACGTCGTCCT CATCTATCAA 
CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA CGACTACGAG ATGGAGAAAG AGGCTGGTTT 
CCTATGGAAT GTGCCAAGGA GATAACATGT CAAGCTACAA TTGATAAGAA TGTGGAGAGA 
ATGGGACGCT TGCTAGGACT GGAGACCAAC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056410.3
CDS	182..2797
Translation	MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV

Target ORF information:

RefSeq Version	NM_015595.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015595.4

ORF Insert Sequence:

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTCA CTGACCCAGG TGGAAATCGT TAGGTCATTT 
ACTGCTAAGC AGCCAGATGA ACTCTCCCTG CAGGTGGCTG ACGTCGTCCT CATCTATCAA 
CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA CGACTACGAG ATGGAGAAAG AGGCTGGTTT 
CCTATGGAAT GTGCCAAGGA GATAACATGT CAAGCTACAA TTGATAAGAA TGTGGAGAGA 
ATGGGACGCT TGCTAGGACT GGAGACCAAC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF26 ( NM_001251963.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238892.1 Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15440
Clone ID Related Accession (Same CDS sequence)	NM_001251963.2 , NM_001251963.1
Accession Version	NM_001251963.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559232000000
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 26 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB069290.1, AK123040.1 and AC018452.11. On Jun 1, 2019 this sequence version replaced NM_001251963.1. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK123040.1, SRR1660809.67952.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTGT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238892.1
CDS	182..2557
Translation	MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTCG

Target ORF information:

RefSeq Version	NM_001251963.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251963.2

ORF Insert Sequence:

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTGT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF26 ( NM_001251963.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238892.1 Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 3, mRNA.

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CloneID	OHu15440
Clone ID Related Accession (Same CDS sequence)	NM_001251963.2 , NM_001251963.1
Accession Version	NM_001251963.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 26 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA248533.1, DB069290.1, AK123040.1 and AC018452.11. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK123040.1, SRR1660809.67952.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTGT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238892.1
CDS	212..2587
Translation	MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTCG

Target ORF information:

RefSeq Version	NM_001251963.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251963.1

ORF Insert Sequence:

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGTTGGT TCGACTATGC 
AATGAGGGCG CCCGGAAGAT GGAAAGGACT GAGATGATGT ACACAATTAA CTCCCAGCTG 
GAATTTAAAA TTAAGCCTTT TCCTTTAGTC TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT 
GAATTGACAG CCTATGTTGA AGACACTGTG CTTTTCTCAA GAAGGACATC CAAACAGCAA 
GTCTACTTCT TTCTCTTTAA CGATGTGCTC ATTATCACCA AGAAGAAGAG TGAAGAAAGT 
TACAACGTCA ATGATTATTC CTTAAGAGAT CAGCTATTGG TGGAATCTTG TGACAATGAA 
GAGCTTAATT CTTCTCCAGG GAAGAACAGC TCCACAATGC TCTATTCAAG ACAGAGCTCT 
GCCAGTCACC TCTTTACTCT GACAGTCCTT AGTAACCACG CGAATGAGAA AGTGGAGATG 
CTACTAGGAG CTGAGACGCA GAGCGAGCGA GCCCGCTGGA TAACTGCCCT GGGACACAGC 
AGCGGGAAGC CGCCTGCAGA CCGAACCTGT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF26 ( XM_011512672.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510974.1 Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu66786
Clone ID Related Accession (Same CDS sequence)	XM_011512672.1
Accession Version	XM_011512672.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2526bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 26 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGCCTTT TCCTTTAGTC 
TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT GAATTGACAG CCTATGTTGA AGACACTGTG 
CTTTTCTCAA GAAGGACATC CAAACAGCAA GTCTACTTCT TTCTCTTTAA CGATGTGCTC 
ATTATCACCA AGAAGAAGAG TGAAGAAAGT TACAACGTCA ATGATTATTC CTTAAGAGAT 
CAGCTATTGG TGGAATCTTG TGACAATGAA GAGCTTAATT CTTCTCCAGG GAAGAACAGC 
TCCACAATGC TCTATTCAAG ACAGAGCTCT GCCAGTCACC TCTTTACTCT GACAGTCCTT 
AGTAACCACG CGAATGAGAA AGTGGAGATG CTACTAGGAG CTGAGACGCA GAGCGAGCGA 
GCCCGCTGGA TAACTGCCCT GGGACACAGC AGCGGGAAGC CGCCTGCAGA CCGAACCTCA 
CTGACCCAGG TGGAAATCGT TAGGTCATTT ACTGCTAAGC AGCCAGATGA ACTCTCCCTG 
CAGGTGGCTG ACGTCGTCCT CATCTATCAA CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA 
CGACTACGAG ATGGAGAAAG AGGCTGGTTT CCTATGGAAT GTGCCAAGGA GATAACATGT 
CAAGCTACAA TTGATAAGAA TGTGGAGAGA ATGGGACGCT TGCTAGGACT GGAGACCAAC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510974.1
CDS	212..2737
Translation	MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV

Target ORF information:

RefSeq Version	XM_011512672.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512672.1

ORF Insert Sequence:

ATGGACGGCG AGAGCGAGGT GGATTTTTCT AGCAACAGCA TAACCCCTTT GTGGCGGAGG 
CGGTCGATTC CTCAGCCCCA CCAGGTTCTG GGCCGGAGCA AGCCGAGGCC CCAGTCCTAC 
CAGAGCCCCA ACGGGTTACT AATTACGGAT TTCCCGGTGG AGGACGGAGG GACGCTCCTC 
GCAGCGCAGA TTCCCGCCCA GGTGCCCACC GCCTCGGACA GCAGGACGGT ACATAGGAGC 
CCCCTGCTTC TGGGCGCCCA GCGGAGAGCG GTGGCCAATG GTGGGACGGC ATCCCCGGAG 
TACAGGGCTG CCTCTCCTCG ACTTCGACGG CCCAAGTCAC CCAAGCTCCC CAAAGCGGTG 
CCTGGCGGCT CCCCGAAATC CCCAGCAAAT GGCGCGGTGA CCTTGCCTGC GCCGCCGCCG 
CCGCCGGTTC TGCGCCCCCC GCGGACTCCT AACGCGCCCG CCCCCTGCAC CCCCGAGGAG 
GACCTTACTG GGTTGACTGC CAGCCCGGTG CCTTCGCCCA CTGCAAATGG CCTTGCCGCT 
AATAACGACT CTCCTGGGTC AGGTTCGCAG TCCGGCCGGA AGGCAAAGGA CCCCGAACGG 
GGGCTCTTTC CTGGGCCCCA GAAAAGTTCT TCGGAACAAA AACTCCCCCT CCAAAGGCTG 
CCCTCCCAGG AGAACGAGCT CCTCGAGAAT CCTTCCGTGG TTTTGAGTAC AAACAGCCCC 
GCCGCCCTCA AAGTGGGGAA GCAGCAGATC ATTCCGAAGA GTCTGGCCTC GGAAATTAAA 
ATAAGTAAAT CCAACAATCA AAATGTGGAG CCCCACAAGA GACTCCTCAA GGTGCGCAGC 
ATGGTGGAGG GCCTAGGAGG ACCCCTGGGT CACGCAGGGG AGGAGAGTGA GGTCGATAAC 
GACGTGGATA GCCCAGGGTC TCTGCGGAGA GGCTTGCGGT CCACGTCTTA TCGCAGGGCA 
GTGGTCAGTG GCTTTGATTT TGACAGTCCT ACCAGCTCGA AGAAGAAGAA CAGAATGTCC 
CAGCCTGTTC TGAAAGTGGT GATGGAAGAC AAGGAGAAGT TTTCCAGTCT GGGAAGGATA 
AAGAAAAAAA TGCTGAAAGG ACAAGGAACA TTTGATGGGG AAGAAAATGC TGTCCTGTAT 
CAAAACTACA AGGAAAAGGC CCTTGACATT GATTCTGATG AAGAGTCAGA GCCCAAAGAA 
CAGAAGTCAG ATGAAAAAAT TGTGATTCAC CATAAGCCAT TGAGATCCAC ATGGAGCCAA 
CTCTCTGCGG TGAAAAGAAA GGGATTATCT CAGACAGTAA GCCAGGAGGA AAGAAAGAGA 
CAAGAGGCTA TCTTTGAAGT CATATCCTCT GAACATTCAT ATTTACTCAG CTTGGAGATC 
TTGATACGAA TGTTTAAAAA TTCTAAAGAA CTGAGTGATA CAATGACTAA AACCGAGAGG 
CACCATCTTT TCTCCAATAT TACAGATGTC TGTGAGGCAA GCAAAAAGTT CTTTATAGAG 
TTGGAAGCAA GACATCAGAA TAATATCTTC ATAGATGACA TAAGTGACAT TGTGGAAAAA 
CACACAGCAT CCACATTTGA CCCATATGTG AAATACTGCA CAAATGAAGT CTACCAACAA 
CGAACACTAC AAAAATTGTT AGCTACCAAT CCATCCTTTA AGGAAGTATT GTCAAGGATT 
GAGTCCCATG AAGACTGTAG GAACTTACCC ATGATCTCTT TTCTCATTCT CCCCATGCAG 
AGGGTGACCC GCCTTCCCCT GCTGATGGAT ACTATCTGTC AAAAAACACC TAAGGACTCT 
CCGAAGTATG AAGTCTGCAA AAGAGCCTTG AAGGAAGTTA GCAAGCCTTT TCCTTTAGTC 
TCCTCTTCCC GGTGGTTGGT AAAAAGAGGT GAATTGACAG CCTATGTTGA AGACACTGTG 
CTTTTCTCAA GAAGGACATC CAAACAGCAA GTCTACTTCT TTCTCTTTAA CGATGTGCTC 
ATTATCACCA AGAAGAAGAG TGAAGAAAGT TACAACGTCA ATGATTATTC CTTAAGAGAT 
CAGCTATTGG TGGAATCTTG TGACAATGAA GAGCTTAATT CTTCTCCAGG GAAGAACAGC 
TCCACAATGC TCTATTCAAG ACAGAGCTCT GCCAGTCACC TCTTTACTCT GACAGTCCTT 
AGTAACCACG CGAATGAGAA AGTGGAGATG CTACTAGGAG CTGAGACGCA GAGCGAGCGA 
GCCCGCTGGA TAACTGCCCT GGGACACAGC AGCGGGAAGC CGCCTGCAGA CCGAACCTCA 
CTGACCCAGG TGGAAATCGT TAGGTCATTT ACTGCTAAGC AGCCAGATGA ACTCTCCCTG 
CAGGTGGCTG ACGTCGTCCT CATCTATCAA CGTGTCAGCG ATGGCTGGTA TGAGGGGGAA 
CGACTACGAG ATGGAGAAAG AGGCTGGTTT CCTATGGAAT GTGCCAAGGA GATAACATGT 
CAAGCTACAA TTGATAAGAA TGTGGAGAGA ATGGGACGCT TGCTAGGACT GGAGACCAAC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF26 ( XM_017006160.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016861649.1 Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant X2, mRNA.

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CloneID	OHu94056
Clone ID Related Accession (Same CDS sequence)	XM_017006160.1
Accession Version	XM_017006160.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 26 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTTG CAGTACTGAA AGTTGCCCTG GAAAATGCTG TCCTGTATCA AAACTACAAG 
GAAAAGGCCC TTGACATTGA TTCTGATGAA GAGTCAGAGC CCAAAGAACA GAAGTCAGAT 
GAAAAAATTG TGATTCACCA TAAGCCATTG AGATCCACAT GGAGCCAACT CTCTGCGGTG 
AAAAGAAAGG GATTATCTCA GACAGTAAGC CAGGAGGAAA GAAAGAGACA AGAGGCTATC 
TTTGAAGTCA TATCCTCTGA ACATTCATAT TTACTCAGCT TGGAGATCTT GATACGAATG 
TTTAAAAATT CTAAAGAACT GAGTGATACA ATGACTAAAA CCGAGAGGCA CCATCTTTTC 
TCCAATATTA CAGATGTCTG TGAGGCAAGC AAAAAGTTCT TTATAGAGTT GGAAGCAAGA 
CATCAGAATA ATATCTTCAT AGATGACATA AGTGACATTG TGGAAAAACA CACAGCATCC 
ACATTTGACC CATATGTGAA ATACTGCACA AATGAAGTCT ACCAACAACG AACACTACAA 
AAATTGTTAG CTACCAATCC ATCCTTTAAG GAAGTATTGT CAAGGATTGA GTCCCATGAA 
GACTGTAGGA ACTTACCCAT GATCTCTTTT CTCATTCTCC CCATGCAGAG GGTGACCCGC 
CTTCCCCTGC TGATGGATAC TATCTGTCAA AAAACACCTA AGGACTCTCC GAAGTATGAA 
GTCTGCAAAA GAGCCTTGAA GGAAGTTAGC AAGTTGGTTC GACTATGCAA TGAGGGCGCC 
CGGAAGATGG AAAGGACTGA GATGATGTAC ACAATTAACT CCCAGCTGGA ATTTAAAATT 
AAGCCTTTTC CTTTAGTCTC CTCTTCCCGG TGGTTGGTAA AAAGAGGTGA ATTGACAGCC 
TATGTTGAAG ACACTGTGCT TTTCTCAAGA AGGACATCCA AACAGCAAGT CTACTTCTTT 
CTCTTTAACG ATGTGCTCAT TATCACCAAG AAGAAGAGTG AAGAAAGTTA CAACGTCAAT 
GATTATTCCT TAAGAGATCA GCTATTGGTG GAATCTTGTG ACAATGAAGA GCTTAATTCT 
TCTCCAGGGA AGAACAGCTC CACAATGCTC TATTCAAGAC AGAGCTCTGC CAGTCACCTC 
TTTACTCTGA CAGTCCTTAG TAACCACGCG AATGAGAAAG TGGAGATGCT ACTAGGAGCT 
GAGACGCAGA GCGAGCGAGC CCGCTGGATA ACTGCCCTGG GACACAGCAG CGGGAAGCCG 
CCTGCAGACC GAACCTCACT GACCCAGGTG GAAATCGTTA GGTCATTTAC TGCTAAGCAG 
CCAGATGAAC TCTCCCTGCA GGTGGCTGAC GTCGTCCTCA TCTATCAACG TGTCAGCGAT 
GGCTGGTATG AGGGGGAACG ACTACGAGAT GGAGAAAGAG GCTGGTTTCC TATGGAATGT 
GCCAAGGAGA TAACATGTCA AGCTACAATT GATAAGAATG TGGAGAGAAT GGGACGCTTG 
CTAGGACTGG AGACCAACGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016861649.1
CDS	46..1569
Translation	MELAVLKVALENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV

Target ORF information:

RefSeq Version	XM_017006160.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 26 (ARHGEF26), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006160.1

ORF Insert Sequence:

ATGGAGCTTG CAGTACTGAA AGTTGCCCTG GAAAATGCTG TCCTGTATCA AAACTACAAG 
GAAAAGGCCC TTGACATTGA TTCTGATGAA GAGTCAGAGC CCAAAGAACA GAAGTCAGAT 
GAAAAAATTG TGATTCACCA TAAGCCATTG AGATCCACAT GGAGCCAACT CTCTGCGGTG 
AAAAGAAAGG GATTATCTCA GACAGTAAGC CAGGAGGAAA GAAAGAGACA AGAGGCTATC 
TTTGAAGTCA TATCCTCTGA ACATTCATAT TTACTCAGCT TGGAGATCTT GATACGAATG 
TTTAAAAATT CTAAAGAACT GAGTGATACA ATGACTAAAA CCGAGAGGCA CCATCTTTTC 
TCCAATATTA CAGATGTCTG TGAGGCAAGC AAAAAGTTCT TTATAGAGTT GGAAGCAAGA 
CATCAGAATA ATATCTTCAT AGATGACATA AGTGACATTG TGGAAAAACA CACAGCATCC 
ACATTTGACC CATATGTGAA ATACTGCACA AATGAAGTCT ACCAACAACG AACACTACAA 
AAATTGTTAG CTACCAATCC ATCCTTTAAG GAAGTATTGT CAAGGATTGA GTCCCATGAA 
GACTGTAGGA ACTTACCCAT GATCTCTTTT CTCATTCTCC CCATGCAGAG GGTGACCCGC 
CTTCCCCTGC TGATGGATAC TATCTGTCAA AAAACACCTA AGGACTCTCC GAAGTATGAA 
GTCTGCAAAA GAGCCTTGAA GGAAGTTAGC AAGTTGGTTC GACTATGCAA TGAGGGCGCC 
CGGAAGATGG AAAGGACTGA GATGATGTAC ACAATTAACT CCCAGCTGGA ATTTAAAATT 
AAGCCTTTTC CTTTAGTCTC CTCTTCCCGG TGGTTGGTAA AAAGAGGTGA ATTGACAGCC 
TATGTTGAAG ACACTGTGCT TTTCTCAAGA AGGACATCCA AACAGCAAGT CTACTTCTTT 
CTCTTTAACG ATGTGCTCAT TATCACCAAG AAGAAGAGTG AAGAAAGTTA CAACGTCAAT 
GATTATTCCT TAAGAGATCA GCTATTGGTG GAATCTTGTG ACAATGAAGA GCTTAATTCT 
TCTCCAGGGA AGAACAGCTC CACAATGCTC TATTCAAGAC AGAGCTCTGC CAGTCACCTC 
TTTACTCTGA CAGTCCTTAG TAACCACGCG AATGAGAAAG TGGAGATGCT ACTAGGAGCT 
GAGACGCAGA GCGAGCGAGC CCGCTGGATA ACTGCCCTGG GACACAGCAG CGGGAAGCCG 
CCTGCAGACC GAACCTCACT GACCCAGGTG GAAATCGTTA GGTCATTTAC TGCTAAGCAG 
CCAGATGAAC TCTCCCTGCA GGTGGCTGAC GTCGTCCTCA TCTATCAACG TGTCAGCGAT 
GGCTGGTATG AGGGGGAACG ACTACGAGAT GGAGAAAGAG GCTGGTTTCC TATGGAATGT 
GCCAAGGAGA TAACATGTCA AGCTACAATT GATAAGAATG TGGAGAGAAT GGGACGCTTG 
CTAGGACTGG AGACCAACGT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SGEF is a potential prognostic and therapeutic target for lung adenocarcinoma.
World journal of surgical oncology16(1)32(2018 Feb)
Chen Q,Lu X,Liu QX,Zhou D,Qiu Y,Dai JG,Zheng H

Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.
Nature genetics49(9)1392-1397(2017 Sep)
Klarin D,Zhu QM,Emdin CA,Chaffin M,Horner S,McMillan BJ,Leed A,Weale ME,Spencer CCA,Aguet F,Segrè AV,Ardlie KG,Khera AV,Kaushik VK,Natarajan P,,Kathiresan S

A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells.
Journal of cell science130(6)1064-1077(2017 03)
Goicoechea SM,Zinn A,Awadia SS,Snyder K,Garcia-Mata R

SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.
Molecular cancer research : MCR14(3)302-12(2016 Mar)
Ensign SP,Roos A,Mathews IT,Dhruv HD,Tuncali S,Sarkaria JN,Symons MH,Loftus JC,Berens ME,Tran NL

Tyrosine Phosphorylation of SGEF Regulates RhoG Activity and Cell Migration.
PloS one11(7)e0159617(2016)
Okuyama Y,Umeda K,Negishi M,Katoh H

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ARHGEF26 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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