| Gene Symbol | FABP5 |
| Entrez Gene ID | 2171 |
| Full Name | fatty acid binding protein 5 |
| Synonyms | E-FABP,EFABP,KFABP,PA-FABP,PAFABP |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]. |
| Disorder MIM: |
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FABP5 cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following FABP5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FABP5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu19667 
Clone ID Related Accession (Same CDS sequence) NM_001444.2 , NM_001444.3 Accession Version NM_001444.2 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 408bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1504972800000 Organism Homo sapiens(human) Product fatty acid-binding protein, epidermal Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN278427.1 and AK226036.1. This sequence is a reference standard in the RefSeqGene project. On Feb 16, 2011 this sequence version replaced NM_001444.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.129004.1, SRR1660805.38197.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361ATGGCCACAG TTCAGCAGCT GGAAGGAAGA TGGCGCCTGG TGGACAGCAA AGGCTTTGAT
GAATACATGA AGGAGCTAGG AGTGGGAATA GCTTTGCGAA AAATGGGCGC AATGGCCAAG
CCAGATTGTA TCATCACTTG TGATGGTAAA AACCTCACCA TAAAAACTGA GAGCACTTTG
AAAACAACAC AGTTTTCTTG TACCCTGGGA GAGAAGTTTG AAGAAACCAC AGCTGATGGC
AGAAAAACTC AGACTGTCTG CAACTTTACA GATGGTGCAT TGGTTCAGCA TCAGGAGTGG
GATGGGAAGG AAAGCACAAT AACAAGAAAA TTGAAAGATG GGAAATTAGT GGTGGAGTGT
GTCATGAACA ATGTCACCTG TACTCGGATC TATGAAAAAG TAGAATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001435.1 CDS 114..521 Translation 
Target ORF information:
RefSeq Version NM_001444.2 Organism Homo sapiens(human) Definition Homo sapiens fatty acid binding protein 5 (FABP5), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001444.2
ORF Insert Sequence:
1
61
121
181
241
301
361ATGGCCACAG TTCAGCAGCT GGAAGGAAGA TGGCGCCTGG TGGACAGCAA AGGCTTTGAT
GAATACATGA AGGAGCTAGG AGTGGGAATA GCTTTGCGAA AAATGGGCGC AATGGCCAAG
CCAGATTGTA TCATCACTTG TGATGGTAAA AACCTCACCA TAAAAACTGA GAGCACTTTG
AAAACAACAC AGTTTTCTTG TACCCTGGGA GAGAAGTTTG AAGAAACCAC AGCTGATGGC
AGAAAAACTC AGACTGTCTG CAACTTTACA GATGGTGCAT TGGTTCAGCA TCAGGAGTGG
GATGGGAAGG AAAGCACAAT AACAAGAAAA TTGAAAGATG GGAAATTAGT GGTGGAGTGT
GTCATGAACA ATGTCACCTG TACTCGGATC TATGAAAAAG TAGAATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu19667 Clone ID Related Accession (Same CDS sequence) NM_001444.2 , NM_001444.3 Accession Version NM_001444.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 408bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577635200000 Organism Homo sapiens(human) Product fatty acid-binding protein 5 Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK226036.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001444.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.178998.1, SRR5189652.209560.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000297258.11/ ENSP00000297258.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.
1
61
121
181
241
301
361ATGGCCACAG TTCAGCAGCT GGAAGGAAGA TGGCGCCTGG TGGACAGCAA AGGCTTTGAT
GAATACATGA AGGAGCTAGG AGTGGGAATA GCTTTGCGAA AAATGGGCGC AATGGCCAAG
CCAGATTGTA TCATCACTTG TGATGGTAAA AACCTCACCA TAAAAACTGA GAGCACTTTG
AAAACAACAC AGTTTTCTTG TACCCTGGGA GAGAAGTTTG AAGAAACCAC AGCTGATGGC
AGAAAAACTC AGACTGTCTG CAACTTTACA GATGGTGCAT TGGTTCAGCA TCAGGAGTGG
GATGGGAAGG AAAGCACAAT AACAAGAAAA TTGAAAGATG GGAAATTAGT GGTGGAGTGT
GTCATGAACA ATGTCACCTG TACTCGGATC TATGAAAAAG TAGAATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001435.1 CDS 61..468 Translation
Target ORF information:
RefSeq Version NM_001444.3 Organism Homo sapiens(human) Definition Homo sapiens fatty acid binding protein 5 (FABP5), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_001444.3
ORF Insert Sequence:
1
61
121
181
241
301
361ATGGCCACAG TTCAGCAGCT GGAAGGAAGA TGGCGCCTGG TGGACAGCAA AGGCTTTGAT
GAATACATGA AGGAGCTAGG AGTGGGAATA GCTTTGCGAA AAATGGGCGC AATGGCCAAG
CCAGATTGTA TCATCACTTG TGATGGTAAA AACCTCACCA TAAAAACTGA GAGCACTTTG
AAAACAACAC AGTTTTCTTG TACCCTGGGA GAGAAGTTTG AAGAAACCAC AGCTGATGGC
AGAAAAACTC AGACTGTCTG CAACTTTACA GATGGTGCAT TGGTTCAGCA TCAGGAGTGG
GATGGGAAGG AAAGCACAAT AACAAGAAAA TTGAAAGATG GGAAATTAGT GGTGGAGTGT
GTCATGAACA ATGTCACCTG TACTCGGATC TATGAAAAAG TAGAATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
FABP5 regulates the proliferation of clear cell renal cell carcinoma cells via the PI3K/AKT signaling pathway.
International journal of oncology54(4)1221-1232(2019 Apr)
Lv Q,Wang G,Zhang Y,Han X,Li H,Le W,Zhang M,Ma C,Wang P,Ding Q
[FABP5 promotes cell growth, invasion and metastasis in cervical cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology]41(3)200-207(2019 Mar)
Zhan YZ,Liu F,Zhang Y,Mo XY,Cheng WD,Wang W
Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes.
Molecular biology of the cell30(3)387-399(2019 02)
Melville D,Gorur A,Schekman R
Epidermal Fatty Acid-Binding Protein: A Novel Marker in the Diagnosis of Dry Eye Disease in Sjögren Syndrome.
International journal of molecular sciences19(11)(2018 Nov)
Shinzawa M,Dogru M,Den S,Ichijima T,Higa K,Kojima T,Seta N,Nomura T,Tsubota K,Shimazaki J
Fatty acid binding protein 5 promotes tumor angiogenesis and activates the IL6/STAT3/VEGFA pathway in hepatocellular carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie10668-76(2018 Oct)
Pan L,Xiao H,Liao R,Chen Q,Peng C,Zhang Y,Mu T,Wu Z
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