EPAS1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EPAS1
Entrez Gene ID	2034
Full Name	endothelial PAS domain protein 1
Synonyms	ECYT4,HIF2A,HLF,MOP2,PASD2,bHLHe73
General protein information	Preferred Names endothelial PAS domain protein 1 Names endothelial PAS domain-containing protein 1 EPAS-1 HIF-1-alpha-like factor HIF-1alpha-like factor HIF-2-alpha HIF2-alpha PAS domain-containing protein 2 basic-helix-loop-helix-PAS protein MOP2 class E basic helix-loop-helix protein 73 hypoxia-inducible factor 2 alpha member of PAS protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p21
Summary	This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009].
Disorder MIM:	603349
Disorder Html:	Erythrocytosis, familial, 4, 611783 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001430.4	NP_001421.2	endothelial PAS domain-containing protein 1
XM_011532698.2	XP_011531000.1	endothelial PAS domain-containing protein 1 isoform X1
NM_001430.5	NP_001421.2	endothelial PAS domain-containing protein 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EPAS1	XP_005626137.1
Rattus norvegicus (Norway rat)	Epas1	NP_075578.1
Macaca mulatta (Rhesus monkey)	EPAS1	XP_001112947.2
Mus musculus (house mouse)	Epas1	NP_034267.3
Pan troglodytes (chimpanzee)	EPAS1	XP_001147219.1
Gallus gallus (chicken)	EPAS1	NP_990138.1
Danio rerio (zebrafish)	epas1b	NP_001034895.1
Xenopus tropicalis (tropical clawed frog)	epas1	NP_001005647.1
Homo sapiens (human)	EPAS1	NP_001421.2
Bos taurus (cattle)	EPAS1	NP_777150.1

Gene Ontology
Bibliography

Related articles in PubMed

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Hypoxia Up-regulates HIF Expression While Suppressing Cell Growth and NOTCH Activity in Leukaemia Cells.
Itoh M, Okuhashi Y, Takahashi Y, Sonoda Y, Mohammad S, Saito T, Shiratori E, Tohda S
Anticancer research39(8)4165-4170(2019 Aug)

Extracellular ATP promotes breast cancer invasion and epithelial-mesenchymal transition via hypoxia-inducible factor 2α signaling.
Yang H, Geng YH, Wang P, Zhou YT, Yang H, Huo YF, Zhang HQ, Li Y, He HY, Tian XX, Fang WG
Cancer science110(8)2456-2470(2019 Aug)

Chiari Malformation Type 1 in
Rosenblum JS, Maggio D, Pang Y, Nazari MA, Gonzales MK, Lechan RM, Smirniotopoulos JG, Zhuang Z, Pacak K, Heiss JD
International journal of molecular sciences20(11)(2019 Jun)

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.
Zou Y, Palte MJ, Deik AA, Li H, Eaton JK, Wang W, Tseng YY, Deasy R, Kost-Alimova M, Dančík V, Leshchiner ES, Viswanathan VS, Signoretti S, Choueiri TK, Boehm JS, Wagner BK, Doench JG, Clish CB, Clemons PA, Schreiber SL
Nature communications10(1)1617(2019 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EPAS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EPAS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23001	NM_001430.5 Latest version!	Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu57508	XM_011532698.2 Latest version!	Homo sapiens endothelial PAS domain protein 1 (EPAS1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OHu23001	NM_001430.4	Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EPAS1 ( NM_001430.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001421.2 Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA.

Price & Availability↑

CloneID	OHu23001
Clone ID Related Accession (Same CDS sequence)	NM_001430.4 , NM_001430.5
Accession Version	NM_001430.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2613bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514649600000
Organism	Homo sapiens(human)
Product	endothelial PAS domain-containing protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC016696.8, CD109908.1, BC051338.1, AK123845.1 and BM671511.1. This sequence is a reference standard in the RefSeqGene project. On Nov 6, 2009 this sequence version replaced NM_001430.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.67820.1, SRR1660803.153586.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAGCTG ACAAGGAGAA GAAAAGGAGT AGCTCGGAGA GGAGGAAGGA GAAGTCCCGG 
GATGCTGCGC GGTGCCGGCG GAGCAAGGAG ACGGAGGTGT TCTATGAGCT GGCCCATGAG 
CTGCCTCTGC CCCACAGTGT GAGCTCCCAT CTGGACAAGG CCTCCATCAT GCGACTGGCA 
ATCAGCTTCC TGCGAACACA CAAGCTCCTC TCCTCAGTTT GCTCTGAAAA CGAGTCCGAA 
GCCGAAGCTG ACCAGCAGAT GGACAACTTG TACCTGAAAG CCTTGGAGGG TTTCATTGCC 
GTGGTGACCC AAGATGGCGA CATGATCTTT CTGTCAGAAA ACATCAGCAA GTTCATGGGA 
CTTACACAGG TGGAGCTAAC AGGACATAGT ATCTTTGACT TCACTCATCC CTGCGACCAT 
GAGGAGATTC GTGAGAACCT GAGTCTCAAA AATGGCTCTG GTTTTGGGAA AAAAAGCAAA 
GACATGTCCA CAGAGCGGGA CTTCTTCATG AGGATGAAGT GCACGGTCAC CAACAGAGGC 
CGTACTGTCA ACCTCAAGTC AGCCACCTGG AAGGTCTTGC ACTGCACGGG CCAGGTGAAA 
GTCTACAACA ACTGCCCTCC TCACAATAGT CTGTGTGGCT ACAAGGAGCC CCTGCTGTCC 
TGCCTCATCA TCATGTGTGA ACCAATCCAG CACCCATCCC ACATGGACAT CCCCCTGGAT 
AGCAAGACCT TCCTGAGCCG CCACAGCATG GACATGAAGT TCACCTACTG TGATGACAGA 
ATCACAGAAC TGATTGGTTA CCACCCTGAG GAGCTGCTTG GCCGCTCAGC CTATGAATTC 
TACCATGCGC TAGACTCCGA GAACATGACC AAGAGTCACC AGAACTTGTG CACCAAGGGT 
CAGGTAGTAA GTGGCCAGTA CCGGATGCTC GCAAAGCATG GGGGCTACGT GTGGCTGGAG 
ACCCAGGGGA CGGTCATCTA CAACCCTCGC AACCTGCAGC CCCAGTGCAT CATGTGTGTC 
AACTACGTCC TGAGTGAGAT TGAGAAGAAT GACGTGGTGT TCTCCATGGA CCAGACTGAA 
TCCCTGTTCA AGCCCCACCT GATGGCCATG AACAGCATCT TTGATAGCAG TGGCAAGGGG 
GCTGTGTCTG AGAAGAGTAA CTTCCTATTC ACCAAGCTAA AGGAGGAGCC CGAGGAGCTG 
GCCCAGCTGG CTCCCACCCC AGGAGACGCC ATCATCTCTC TGGATTTCGG GAATCAGAAC 
TTCGAGGAGT CCTCAGCCTA TGGCAAGGCC ATCCTGCCCC CGAGCCAGCC ATGGGCCACG 
GAGTTGAGGA GCCACAGCAC CCAGAGCGAG GCTGGGAGCC TGCCTGCCTT CACCGTGCCC 
CAGGCAGCTG CCCCGGGCAG CACCACCCCC AGTGCCACCA GCAGCAGCAG CAGCTGCTCC 
ACGCCCAATA GCCCTGAAGA CTATTACACA TCTTTGGATA ACGACCTGAA GATTGAAGTG 
ATTGAGAAGC TCTTCGCCAT GGACACAGAG GCCAAGGACC AATGCAGTAC CCAGACGGAT 
TTCAATGAGC TGGACTTGGA GACACTGGCA CCCTATATCC CCATGGACGG GGAAGACTTC 
CAGCTAAGCC CCATCTGCCC CGAGGAGCGG CTCTTGGCGG AGAACCCACA GTCCACCCCC 
CAGCACTGCT TCAGTGCCAT GACAAACATC TTCCAGCCAC TGGCCCCTGT AGCCCCGCAC 
AGTCCCTTCC TCCTGGACAA GTTTCAGCAG CAGCTGGAGA GCAAGAAGAC AGAGCCCGAG 
CACCGGCCCA TGTCCTCCAT CTTCTTTGAT GCCGGAAGCA AAGCATCCCT GCCACCGTGC 
TGTGGCCAGG CCAGCACCCC TCTCTCTTCC ATGGGGGGCA GATCCAATAC CCAGTGGCCC 
CCAGATCCAC CATTACATTT TGGGCCCACA AAGTGGGCCG TCGGGGATCA GCGCACAGAG 
TTCTTGGGAG CAGCGCCGTT GGGGCCCCCT GTCTCTCCAC CCCATGTCTC CACCTTCAAG 
ACAAGGTCTG CAAAGGGTTT TGGGGCTCGA GGCCCAGACG TGCTGAGTCC GGCCATGGTA 
GCCCTCTCCA ACAAGCTGAA GCTGAAGCGA CAGCTGGAGT ATGAAGAGCA AGCCTTCCAG 
GACCTGAGCG GGGGGGACCC ACCTGGTGGC AGCACCTCAC ATTTGATGTG GAAACGGATG 
AAGAACCTCA GGGGTGGGAG CTGCCCTTTG ATGCCGGACA AGCCACTGAG CGCAAATGTA 
CCCAATGATA AGTTCACCCA AAACCCCATG AGGGGCCTGG GCCATCCCCT GAGACATCTG 
CCGCTGCCAC AGCCTCCATC TGCCATCAGT CCCGGGGAGA ACAGCAAGAG CAGGTTCCCC 
CCACAGTGCT ACGCCACCCA GTACCAGGAC TACAGCCTGT CGTCAGCCCA CAAGGTGTCA 
GGCATGGCAA GCCGGCTGCT CGGGCCCTCA TTTGAGTCCT ACCTGCTGCC CGAACTGACC 
AGATATGACT GTGAGGTGAA CGTGCCCGTG CTGGGAAGCT CCACGCTCCT GCAAGGAGGG 
GACCTCCTCA GAGCCCTGGA CCAGGCCACC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001421.2
CDS	511..3123
Translation	MTADKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKSKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSGKGAVSEKSNFLFTKLKEEPEELAQLAPTPGDAIISLDFGNQNFEESSAYGKAILPPSQPWATELRSHSTQSEAGSLPAFTVPQAAAPGSTTPSATSSSSSCSTPNSPEDYYTSLDNDLKIEVIEKLFAMDTEAKDQCSTQTDFNELDLETLAPYIPMDGEDFQLSPICPEERLLAENPQSTPQHCFSAMTNIFQPLAPVAPHSPFLLDKFQQQLESKKTEPEHRPMSSIFFDAGSKASLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAPLGPPVSPPHVSTFKTRSAKGFGARGPDVLSPAMVALSNKLKLKRQLEYEEQAFQDLSGGDPPGGSTSHLMWKRMKNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHLPLPQPPSAISPGENSKSRFPPQCYATQYQDYSLSSAHKVSGMASRLLGPSFESYLLPELTRYDCEVNVPVLGSSTLLQGGDLLRALDQAT

Target ORF information:

RefSeq Version	NM_001430.4
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001430.4

ORF Insert Sequence:

ATGACAGCTG ACAAGGAGAA GAAAAGGAGT AGCTCGGAGA GGAGGAAGGA GAAGTCCCGG 
GATGCTGCGC GGTGCCGGCG GAGCAAGGAG ACGGAGGTGT TCTATGAGCT GGCCCATGAG 
CTGCCTCTGC CCCACAGTGT GAGCTCCCAT CTGGACAAGG CCTCCATCAT GCGACTGGCA 
ATCAGCTTCC TGCGAACACA CAAGCTCCTC TCCTCAGTTT GCTCTGAAAA CGAGTCCGAA 
GCCGAAGCTG ACCAGCAGAT GGACAACTTG TACCTGAAAG CCTTGGAGGG TTTCATTGCC 
GTGGTGACCC AAGATGGCGA CATGATCTTT CTGTCAGAAA ACATCAGCAA GTTCATGGGA 
CTTACACAGG TGGAGCTAAC AGGACATAGT ATCTTTGACT TCACTCATCC CTGCGACCAT 
GAGGAGATTC GTGAGAACCT GAGTCTCAAA AATGGCTCTG GTTTTGGGAA AAAAAGCAAA 
GACATGTCCA CAGAGCGGGA CTTCTTCATG AGGATGAAGT GCACGGTCAC CAACAGAGGC 
CGTACTGTCA ACCTCAAGTC AGCCACCTGG AAGGTCTTGC ACTGCACGGG CCAGGTGAAA 
GTCTACAACA ACTGCCCTCC TCACAATAGT CTGTGTGGCT ACAAGGAGCC CCTGCTGTCC 
TGCCTCATCA TCATGTGTGA ACCAATCCAG CACCCATCCC ACATGGACAT CCCCCTGGAT 
AGCAAGACCT TCCTGAGCCG CCACAGCATG GACATGAAGT TCACCTACTG TGATGACAGA 
ATCACAGAAC TGATTGGTTA CCACCCTGAG GAGCTGCTTG GCCGCTCAGC CTATGAATTC 
TACCATGCGC TAGACTCCGA GAACATGACC AAGAGTCACC AGAACTTGTG CACCAAGGGT 
CAGGTAGTAA GTGGCCAGTA CCGGATGCTC GCAAAGCATG GGGGCTACGT GTGGCTGGAG 
ACCCAGGGGA CGGTCATCTA CAACCCTCGC AACCTGCAGC CCCAGTGCAT CATGTGTGTC 
AACTACGTCC TGAGTGAGAT TGAGAAGAAT GACGTGGTGT TCTCCATGGA CCAGACTGAA 
TCCCTGTTCA AGCCCCACCT GATGGCCATG AACAGCATCT TTGATAGCAG TGGCAAGGGG 
GCTGTGTCTG AGAAGAGTAA CTTCCTATTC ACCAAGCTAA AGGAGGAGCC CGAGGAGCTG 
GCCCAGCTGG CTCCCACCCC AGGAGACGCC ATCATCTCTC TGGATTTCGG GAATCAGAAC 
TTCGAGGAGT CCTCAGCCTA TGGCAAGGCC ATCCTGCCCC CGAGCCAGCC ATGGGCCACG 
GAGTTGAGGA GCCACAGCAC CCAGAGCGAG GCTGGGAGCC TGCCTGCCTT CACCGTGCCC 
CAGGCAGCTG CCCCGGGCAG CACCACCCCC AGTGCCACCA GCAGCAGCAG CAGCTGCTCC 
ACGCCCAATA GCCCTGAAGA CTATTACACA TCTTTGGATA ACGACCTGAA GATTGAAGTG 
ATTGAGAAGC TCTTCGCCAT GGACACAGAG GCCAAGGACC AATGCAGTAC CCAGACGGAT 
TTCAATGAGC TGGACTTGGA GACACTGGCA CCCTATATCC CCATGGACGG GGAAGACTTC 
CAGCTAAGCC CCATCTGCCC CGAGGAGCGG CTCTTGGCGG AGAACCCACA GTCCACCCCC 
CAGCACTGCT TCAGTGCCAT GACAAACATC TTCCAGCCAC TGGCCCCTGT AGCCCCGCAC 
AGTCCCTTCC TCCTGGACAA GTTTCAGCAG CAGCTGGAGA GCAAGAAGAC AGAGCCCGAG 
CACCGGCCCA TGTCCTCCAT CTTCTTTGAT GCCGGAAGCA AAGCATCCCT GCCACCGTGC 
TGTGGCCAGG CCAGCACCCC TCTCTCTTCC ATGGGGGGCA GATCCAATAC CCAGTGGCCC 
CCAGATCCAC CATTACATTT TGGGCCCACA AAGTGGGCCG TCGGGGATCA GCGCACAGAG 
TTCTTGGGAG CAGCGCCGTT GGGGCCCCCT GTCTCTCCAC CCCATGTCTC CACCTTCAAG 
ACAAGGTCTG CAAAGGGTTT TGGGGCTCGA GGCCCAGACG TGCTGAGTCC GGCCATGGTA 
GCCCTCTCCA ACAAGCTGAA GCTGAAGCGA CAGCTGGAGT ATGAAGAGCA AGCCTTCCAG 
GACCTGAGCG GGGGGGACCC ACCTGGTGGC AGCACCTCAC ATTTGATGTG GAAACGGATG 
AAGAACCTCA GGGGTGGGAG CTGCCCTTTG ATGCCGGACA AGCCACTGAG CGCAAATGTA 
CCCAATGATA AGTTCACCCA AAACCCCATG AGGGGCCTGG GCCATCCCCT GAGACATCTG 
CCGCTGCCAC AGCCTCCATC TGCCATCAGT CCCGGGGAGA ACAGCAAGAG CAGGTTCCCC 
CCACAGTGCT ACGCCACCCA GTACCAGGAC TACAGCCTGT CGTCAGCCCA CAAGGTGTCA 
GGCATGGCAA GCCGGCTGCT CGGGCCCTCA TTTGAGTCCT ACCTGCTGCC CGAACTGACC 
AGATATGACT GTGAGGTGAA CGTGCCCGTG CTGGGAAGCT CCACGCTCCT GCAAGGAGGG 
GACCTCCTCA GAGCCCTGGA CCAGGCCACC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EPAS1 ( NM_001430.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001421.2 Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA.

Price & Availability↑

CloneID	OHu23001
Clone ID Related Accession (Same CDS sequence)	NM_001430.4 , NM_001430.5
Accession Version	NM_001430.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2613bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	endothelial PAS domain-containing protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC016696.8, CD109908.1, BC051338.1 and AK123845.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001430.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.156330.1, SRR1660803.67820.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263734.5/ ENSP00000263734.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACAGCTG ACAAGGAGAA GAAAAGGAGT AGCTCGGAGA GGAGGAAGGA GAAGTCCCGG 
GATGCTGCGC GGTGCCGGCG GAGCAAGGAG ACGGAGGTGT TCTATGAGCT GGCCCATGAG 
CTGCCTCTGC CCCACAGTGT GAGCTCCCAT CTGGACAAGG CCTCCATCAT GCGACTGGCA 
ATCAGCTTCC TGCGAACACA CAAGCTCCTC TCCTCAGTTT GCTCTGAAAA CGAGTCCGAA 
GCCGAAGCTG ACCAGCAGAT GGACAACTTG TACCTGAAAG CCTTGGAGGG TTTCATTGCC 
GTGGTGACCC AAGATGGCGA CATGATCTTT CTGTCAGAAA ACATCAGCAA GTTCATGGGA 
CTTACACAGG TGGAGCTAAC AGGACATAGT ATCTTTGACT TCACTCATCC CTGCGACCAT 
GAGGAGATTC GTGAGAACCT GAGTCTCAAA AATGGCTCTG GTTTTGGGAA AAAAAGCAAA 
GACATGTCCA CAGAGCGGGA CTTCTTCATG AGGATGAAGT GCACGGTCAC CAACAGAGGC 
CGTACTGTCA ACCTCAAGTC AGCCACCTGG AAGGTCTTGC ACTGCACGGG CCAGGTGAAA 
GTCTACAACA ACTGCCCTCC TCACAATAGT CTGTGTGGCT ACAAGGAGCC CCTGCTGTCC 
TGCCTCATCA TCATGTGTGA ACCAATCCAG CACCCATCCC ACATGGACAT CCCCCTGGAT 
AGCAAGACCT TCCTGAGCCG CCACAGCATG GACATGAAGT TCACCTACTG TGATGACAGA 
ATCACAGAAC TGATTGGTTA CCACCCTGAG GAGCTGCTTG GCCGCTCAGC CTATGAATTC 
TACCATGCGC TAGACTCCGA GAACATGACC AAGAGTCACC AGAACTTGTG CACCAAGGGT 
CAGGTAGTAA GTGGCCAGTA CCGGATGCTC GCAAAGCATG GGGGCTACGT GTGGCTGGAG 
ACCCAGGGGA CGGTCATCTA CAACCCTCGC AACCTGCAGC CCCAGTGCAT CATGTGTGTC 
AACTACGTCC TGAGTGAGAT TGAGAAGAAT GACGTGGTGT TCTCCATGGA CCAGACTGAA 
TCCCTGTTCA AGCCCCACCT GATGGCCATG AACAGCATCT TTGATAGCAG TGGCAAGGGG 
GCTGTGTCTG AGAAGAGTAA CTTCCTATTC ACCAAGCTAA AGGAGGAGCC CGAGGAGCTG 
GCCCAGCTGG CTCCCACCCC AGGAGACGCC ATCATCTCTC TGGATTTCGG GAATCAGAAC 
TTCGAGGAGT CCTCAGCCTA TGGCAAGGCC ATCCTGCCCC CGAGCCAGCC ATGGGCCACG 
GAGTTGAGGA GCCACAGCAC CCAGAGCGAG GCTGGGAGCC TGCCTGCCTT CACCGTGCCC 
CAGGCAGCTG CCCCGGGCAG CACCACCCCC AGTGCCACCA GCAGCAGCAG CAGCTGCTCC 
ACGCCCAATA GCCCTGAAGA CTATTACACA TCTTTGGATA ACGACCTGAA GATTGAAGTG 
ATTGAGAAGC TCTTCGCCAT GGACACAGAG GCCAAGGACC AATGCAGTAC CCAGACGGAT 
TTCAATGAGC TGGACTTGGA GACACTGGCA CCCTATATCC CCATGGACGG GGAAGACTTC 
CAGCTAAGCC CCATCTGCCC CGAGGAGCGG CTCTTGGCGG AGAACCCACA GTCCACCCCC 
CAGCACTGCT TCAGTGCCAT GACAAACATC TTCCAGCCAC TGGCCCCTGT AGCCCCGCAC 
AGTCCCTTCC TCCTGGACAA GTTTCAGCAG CAGCTGGAGA GCAAGAAGAC AGAGCCCGAG 
CACCGGCCCA TGTCCTCCAT CTTCTTTGAT GCCGGAAGCA AAGCATCCCT GCCACCGTGC 
TGTGGCCAGG CCAGCACCCC TCTCTCTTCC ATGGGGGGCA GATCCAATAC CCAGTGGCCC 
CCAGATCCAC CATTACATTT TGGGCCCACA AAGTGGGCCG TCGGGGATCA GCGCACAGAG 
TTCTTGGGAG CAGCGCCGTT GGGGCCCCCT GTCTCTCCAC CCCATGTCTC CACCTTCAAG 
ACAAGGTCTG CAAAGGGTTT TGGGGCTCGA GGCCCAGACG TGCTGAGTCC GGCCATGGTA 
GCCCTCTCCA ACAAGCTGAA GCTGAAGCGA CAGCTGGAGT ATGAAGAGCA AGCCTTCCAG 
GACCTGAGCG GGGGGGACCC ACCTGGTGGC AGCACCTCAC ATTTGATGTG GAAACGGATG 
AAGAACCTCA GGGGTGGGAG CTGCCCTTTG ATGCCGGACA AGCCACTGAG CGCAAATGTA 
CCCAATGATA AGTTCACCCA AAACCCCATG AGGGGCCTGG GCCATCCCCT GAGACATCTG 
CCGCTGCCAC AGCCTCCATC TGCCATCAGT CCCGGGGAGA ACAGCAAGAG CAGGTTCCCC 
CCACAGTGCT ACGCCACCCA GTACCAGGAC TACAGCCTGT CGTCAGCCCA CAAGGTGTCA 
GGCATGGCAA GCCGGCTGCT CGGGCCCTCA TTTGAGTCCT ACCTGCTGCC CGAACTGACC 
AGATATGACT GTGAGGTGAA CGTGCCCGTG CTGGGAAGCT CCACGCTCCT GCAAGGAGGG 
GACCTCCTCA GAGCCCTGGA CCAGGCCACC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001421.2
CDS	506..3118
Translation	MTADKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKSKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSGKGAVSEKSNFLFTKLKEEPEELAQLAPTPGDAIISLDFGNQNFEESSAYGKAILPPSQPWATELRSHSTQSEAGSLPAFTVPQAAAPGSTTPSATSSSSSCSTPNSPEDYYTSLDNDLKIEVIEKLFAMDTEAKDQCSTQTDFNELDLETLAPYIPMDGEDFQLSPICPEERLLAENPQSTPQHCFSAMTNIFQPLAPVAPHSPFLLDKFQQQLESKKTEPEHRPMSSIFFDAGSKASLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAPLGPPVSPPHVSTFKTRSAKGFGARGPDVLSPAMVALSNKLKLKRQLEYEEQAFQDLSGGDPPGGSTSHLMWKRMKNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHLPLPQPPSAISPGENSKSRFPPQCYATQYQDYSLSSAHKVSGMASRLLGPSFESYLLPELTRYDCEVNVPVLGSSTLLQGGDLLRALDQAT

Target ORF information:

RefSeq Version	NM_001430.5
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001430.5

ORF Insert Sequence:

ATGACAGCTG ACAAGGAGAA GAAAAGGAGT AGCTCGGAGA GGAGGAAGGA GAAGTCCCGG 
GATGCTGCGC GGTGCCGGCG GAGCAAGGAG ACGGAGGTGT TCTATGAGCT GGCCCATGAG 
CTGCCTCTGC CCCACAGTGT GAGCTCCCAT CTGGACAAGG CCTCCATCAT GCGACTGGCA 
ATCAGCTTCC TGCGAACACA CAAGCTCCTC TCCTCAGTTT GCTCTGAAAA CGAGTCCGAA 
GCCGAAGCTG ACCAGCAGAT GGACAACTTG TACCTGAAAG CCTTGGAGGG TTTCATTGCC 
GTGGTGACCC AAGATGGCGA CATGATCTTT CTGTCAGAAA ACATCAGCAA GTTCATGGGA 
CTTACACAGG TGGAGCTAAC AGGACATAGT ATCTTTGACT TCACTCATCC CTGCGACCAT 
GAGGAGATTC GTGAGAACCT GAGTCTCAAA AATGGCTCTG GTTTTGGGAA AAAAAGCAAA 
GACATGTCCA CAGAGCGGGA CTTCTTCATG AGGATGAAGT GCACGGTCAC CAACAGAGGC 
CGTACTGTCA ACCTCAAGTC AGCCACCTGG AAGGTCTTGC ACTGCACGGG CCAGGTGAAA 
GTCTACAACA ACTGCCCTCC TCACAATAGT CTGTGTGGCT ACAAGGAGCC CCTGCTGTCC 
TGCCTCATCA TCATGTGTGA ACCAATCCAG CACCCATCCC ACATGGACAT CCCCCTGGAT 
AGCAAGACCT TCCTGAGCCG CCACAGCATG GACATGAAGT TCACCTACTG TGATGACAGA 
ATCACAGAAC TGATTGGTTA CCACCCTGAG GAGCTGCTTG GCCGCTCAGC CTATGAATTC 
TACCATGCGC TAGACTCCGA GAACATGACC AAGAGTCACC AGAACTTGTG CACCAAGGGT 
CAGGTAGTAA GTGGCCAGTA CCGGATGCTC GCAAAGCATG GGGGCTACGT GTGGCTGGAG 
ACCCAGGGGA CGGTCATCTA CAACCCTCGC AACCTGCAGC CCCAGTGCAT CATGTGTGTC 
AACTACGTCC TGAGTGAGAT TGAGAAGAAT GACGTGGTGT TCTCCATGGA CCAGACTGAA 
TCCCTGTTCA AGCCCCACCT GATGGCCATG AACAGCATCT TTGATAGCAG TGGCAAGGGG 
GCTGTGTCTG AGAAGAGTAA CTTCCTATTC ACCAAGCTAA AGGAGGAGCC CGAGGAGCTG 
GCCCAGCTGG CTCCCACCCC AGGAGACGCC ATCATCTCTC TGGATTTCGG GAATCAGAAC 
TTCGAGGAGT CCTCAGCCTA TGGCAAGGCC ATCCTGCCCC CGAGCCAGCC ATGGGCCACG 
GAGTTGAGGA GCCACAGCAC CCAGAGCGAG GCTGGGAGCC TGCCTGCCTT CACCGTGCCC 
CAGGCAGCTG CCCCGGGCAG CACCACCCCC AGTGCCACCA GCAGCAGCAG CAGCTGCTCC 
ACGCCCAATA GCCCTGAAGA CTATTACACA TCTTTGGATA ACGACCTGAA GATTGAAGTG 
ATTGAGAAGC TCTTCGCCAT GGACACAGAG GCCAAGGACC AATGCAGTAC CCAGACGGAT 
TTCAATGAGC TGGACTTGGA GACACTGGCA CCCTATATCC CCATGGACGG GGAAGACTTC 
CAGCTAAGCC CCATCTGCCC CGAGGAGCGG CTCTTGGCGG AGAACCCACA GTCCACCCCC 
CAGCACTGCT TCAGTGCCAT GACAAACATC TTCCAGCCAC TGGCCCCTGT AGCCCCGCAC 
AGTCCCTTCC TCCTGGACAA GTTTCAGCAG CAGCTGGAGA GCAAGAAGAC AGAGCCCGAG 
CACCGGCCCA TGTCCTCCAT CTTCTTTGAT GCCGGAAGCA AAGCATCCCT GCCACCGTGC 
TGTGGCCAGG CCAGCACCCC TCTCTCTTCC ATGGGGGGCA GATCCAATAC CCAGTGGCCC 
CCAGATCCAC CATTACATTT TGGGCCCACA AAGTGGGCCG TCGGGGATCA GCGCACAGAG 
TTCTTGGGAG CAGCGCCGTT GGGGCCCCCT GTCTCTCCAC CCCATGTCTC CACCTTCAAG 
ACAAGGTCTG CAAAGGGTTT TGGGGCTCGA GGCCCAGACG TGCTGAGTCC GGCCATGGTA 
GCCCTCTCCA ACAAGCTGAA GCTGAAGCGA CAGCTGGAGT ATGAAGAGCA AGCCTTCCAG 
GACCTGAGCG GGGGGGACCC ACCTGGTGGC AGCACCTCAC ATTTGATGTG GAAACGGATG 
AAGAACCTCA GGGGTGGGAG CTGCCCTTTG ATGCCGGACA AGCCACTGAG CGCAAATGTA 
CCCAATGATA AGTTCACCCA AAACCCCATG AGGGGCCTGG GCCATCCCCT GAGACATCTG 
CCGCTGCCAC AGCCTCCATC TGCCATCAGT CCCGGGGAGA ACAGCAAGAG CAGGTTCCCC 
CCACAGTGCT ACGCCACCCA GTACCAGGAC TACAGCCTGT CGTCAGCCCA CAAGGTGTCA 
GGCATGGCAA GCCGGCTGCT CGGGCCCTCA TTTGAGTCCT ACCTGCTGCC CGAACTGACC 
AGATATGACT GTGAGGTGAA CGTGCCCGTG CTGGGAAGCT CCACGCTCCT GCAAGGAGGG 
GACCTCCTCA GAGCCCTGGA CCAGGCCACC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EPAS1 ( XM_011532698.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011531000.1 Homo sapiens endothelial PAS domain protein 1 (EPAS1), transcript variant X1, mRNA.

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CloneID	OHu57508
Clone ID Related Accession (Same CDS sequence)	XM_011532698.2
Accession Version	XM_011532698.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2652bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	endothelial PAS domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532698.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTAGGGC TTTTTGTTTT TAAAACAGGG ACACAAAGAA GAAACAGAAG GCTGCCATAT 
GCAAGGAGTA GCTCGGAGAG GAGGAAGGAG AAGTCCCGGG ATGCTGCGCG GTGCCGGCGG 
AGCAAGGAGA CGGAGGTGTT CTATGAGCTG GCCCATGAGC TGCCTCTGCC CCACAGTGTG 
AGCTCCCATC TGGACAAGGC CTCCATCATG CGACTGGCAA TCAGCTTCCT GCGAACACAC 
AAGCTCCTCT CCTCAGTTTG CTCTGAAAAC GAGTCCGAAG CCGAAGCTGA CCAGCAGATG 
GACAACTTGT ACCTGAAAGC CTTGGAGGGT TTCATTGCCG TGGTGACCCA AGATGGCGAC 
ATGATCTTTC TGTCAGAAAA CATCAGCAAG TTCATGGGAC TTACACAGGT GGAGCTAACA 
GGACATAGTA TCTTTGACTT CACTCATCCC TGCGACCATG AGGAGATTCG TGAGAACCTG 
AGTCTCAAAA ATGGCTCTGG TTTTGGGAAA AAAAGCAAAG ACATGTCCAC AGAGCGGGAC 
TTCTTCATGA GGATGAAGTG CACGGTCACC AACAGAGGCC GTACTGTCAA CCTCAAGTCA 
GCCACCTGGA AGGTCTTGCA CTGCACGGGC CAGGTGAAAG TCTACAACAA CTGCCCTCCT 
CACAATAGTC TGTGTGGCTA CAAGGAGCCC CTGCTGTCCT GCCTCATCAT CATGTGTGAA 
CCAATCCAGC ACCCATCCCA CATGGACATC CCCCTGGATA GCAAGACCTT CCTGAGCCGC 
CACAGCATGG ACATGAAGTT CACCTACTGT GATGACAGAA TCACAGAACT GATTGGTTAC 
CACCCTGAGG AGCTGCTTGG CCGCTCAGCC TATGAATTCT ACCATGCGCT AGACTCCGAG 
AACATGACCA AGAGTCACCA GAACTTGTGC ACCAAGGGTC AGGTAGTAAG TGGCCAGTAC 
CGGATGCTCG CAAAGCATGG GGGCTACGTG TGGCTGGAGA CCCAGGGGAC GGTCATCTAC 
AACCCTCGCA ACCTGCAGCC CCAGTGCATC ATGTGTGTCA ACTACGTCCT GAGTGAGATT 
GAGAAGAATG ACGTGGTGTT CTCCATGGAC CAGACTGAAT CCCTGTTCAA GCCCCACCTG 
ATGGCCATGA ACAGCATCTT TGATAGCAGT GGCAAGGGGG CTGTGTCTGA GAAGAGTAAC 
TTCCTATTCA CCAAGCTAAA GGAGGAGCCC GAGGAGCTGG CCCAGCTGGC TCCCACCCCA 
GGAGACGCCA TCATCTCTCT GGATTTCGGG AATCAGAACT TCGAGGAGTC CTCAGCCTAT 
GGCAAGGCCA TCCTGCCCCC GAGCCAGCCA TGGGCCACGG AGTTGAGGAG CCACAGCACC 
CAGAGCGAGG CTGGGAGCCT GCCTGCCTTC ACCGTGCCCC AGGCAGCTGC CCCGGGCAGC 
ACCACCCCCA GTGCCACCAG CAGCAGCAGC AGCTGCTCCA CGCCCAATAG CCCTGAAGAC 
TATTACACAT CTTTGGATAA CGACCTGAAG ATTGAAGTGA TTGAGAAGCT CTTCGCCATG 
GACACAGAGG CCAAGGACCA ATGCAGTACC CAGACGGATT TCAATGAGCT GGACTTGGAG 
ACACTGGCAC CCTATATCCC CATGGACGGG GAAGACTTCC AGCTAAGCCC CATCTGCCCC 
GAGGAGCGGC TCTTGGCGGA GAACCCACAG TCCACCCCCC AGCACTGCTT CAGTGCCATG 
ACAAACATCT TCCAGCCACT GGCCCCTGTA GCCCCGCACA GTCCCTTCCT CCTGGACAAG 
TTTCAGCAGC AGCTGGAGAG CAAGAAGACA GAGCCCGAGC ACCGGCCCAT GTCCTCCATC 
TTCTTTGATG CCGGAAGCAA AGCATCCCTG CCACCGTGCT GTGGCCAGGC CAGCACCCCT 
CTCTCTTCCA TGGGGGGCAG ATCCAATACC CAGTGGCCCC CAGATCCACC ATTACATTTT 
GGGCCCACAA AGTGGGCCGT CGGGGATCAG CGCACAGAGT TCTTGGGAGC AGCGCCGTTG 
GGGCCCCCTG TCTCTCCACC CCATGTCTCC ACCTTCAAGA CAAGGTCTGC AAAGGGTTTT 
GGGGCTCGAG GCCCAGACGT GCTGAGTCCG GCCATGGTAG CCCTCTCCAA CAAGCTGAAG 
CTGAAGCGAC AGCTGGAGTA TGAAGAGCAA GCCTTCCAGG ACCTGAGCGG GGGGGACCCA 
CCTGGTGGCA GCACCTCACA TTTGATGTGG AAACGGATGA AGAACCTCAG GGGTGGGAGC 
TGCCCTTTGA TGCCGGACAA GCCACTGAGC GCAAATGTAC CCAATGATAA GTTCACCCAA 
AACCCCATGA GGGGCCTGGG CCATCCCCTG AGACATCTGC CGCTGCCACA GCCTCCATCT 
GCCATCAGTC CCGGGGAGAA CAGCAAGAGC AGGTTCCCCC CACAGTGCTA CGCCACCCAG 
TACCAGGACT ACAGCCTGTC GTCAGCCCAC AAGGTGTCAG GCATGGCAAG CCGGCTGCTC 
GGGCCCTCAT TTGAGTCCTA CCTGCTGCCC GAACTGACCA GATATGACTG TGAGGTGAAC 
GTGCCCGTGC TGGGAAGCTC CACGCTCCTG CAAGGAGGGG ACCTCCTCAG AGCCCTGGAC 
CAGGCCACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011531000.1
CDS	230..2881
Translation	MLGLFVFKTGTQRRNRRLPYARSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKSKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSGKGAVSEKSNFLFTKLKEEPEELAQLAPTPGDAIISLDFGNQNFEESSAYGKAILPPSQPWATELRSHSTQSEAGSLPAFTVPQAAAPGSTTPSATSSSSSCSTPNSPEDYYTSLDNDLKIEVIEKLFAMDTEAKDQCSTQTDFNELDLETLAPYIPMDGEDFQLSPICPEERLLAENPQSTPQHCFSAMTNIFQPLAPVAPHSPFLLDKFQQQLESKKTEPEHRPMSSIFFDAGSKASLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAPLGPPVSPPHVSTFKTRSAKGFGARGPDVLSPAMVALSNKLKLKRQLEYEEQAFQDLSGGDPPGGSTSHLMWKRMKNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHLPLPQPPSAISPGENSKSRFPPQCYATQYQDYSLSSAHKVSGMASRLLGPSFESYLLPELTRYDCEVNVPVLGSSTLLQGGDLLRALDQAT

Target ORF information:

RefSeq Version	XM_011532698.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endothelial PAS domain protein 1 (EPAS1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532698.2

ORF Insert Sequence:

ATGTTAGGGC TTTTTGTTTT TAAAACAGGG ACACAAAGAA GAAACAGAAG GCTGCCATAT 
GCAAGGAGTA GCTCGGAGAG GAGGAAGGAG AAGTCCCGGG ATGCTGCGCG GTGCCGGCGG 
AGCAAGGAGA CGGAGGTGTT CTATGAGCTG GCCCATGAGC TGCCTCTGCC CCACAGTGTG 
AGCTCCCATC TGGACAAGGC CTCCATCATG CGACTGGCAA TCAGCTTCCT GCGAACACAC 
AAGCTCCTCT CCTCAGTTTG CTCTGAAAAC GAGTCCGAAG CCGAAGCTGA CCAGCAGATG 
GACAACTTGT ACCTGAAAGC CTTGGAGGGT TTCATTGCCG TGGTGACCCA AGATGGCGAC 
ATGATCTTTC TGTCAGAAAA CATCAGCAAG TTCATGGGAC TTACACAGGT GGAGCTAACA 
GGACATAGTA TCTTTGACTT CACTCATCCC TGCGACCATG AGGAGATTCG TGAGAACCTG 
AGTCTCAAAA ATGGCTCTGG TTTTGGGAAA AAAAGCAAAG ACATGTCCAC AGAGCGGGAC 
TTCTTCATGA GGATGAAGTG CACGGTCACC AACAGAGGCC GTACTGTCAA CCTCAAGTCA 
GCCACCTGGA AGGTCTTGCA CTGCACGGGC CAGGTGAAAG TCTACAACAA CTGCCCTCCT 
CACAATAGTC TGTGTGGCTA CAAGGAGCCC CTGCTGTCCT GCCTCATCAT CATGTGTGAA 
CCAATCCAGC ACCCATCCCA CATGGACATC CCCCTGGATA GCAAGACCTT CCTGAGCCGC 
CACAGCATGG ACATGAAGTT CACCTACTGT GATGACAGAA TCACAGAACT GATTGGTTAC 
CACCCTGAGG AGCTGCTTGG CCGCTCAGCC TATGAATTCT ACCATGCGCT AGACTCCGAG 
AACATGACCA AGAGTCACCA GAACTTGTGC ACCAAGGGTC AGGTAGTAAG TGGCCAGTAC 
CGGATGCTCG CAAAGCATGG GGGCTACGTG TGGCTGGAGA CCCAGGGGAC GGTCATCTAC 
AACCCTCGCA ACCTGCAGCC CCAGTGCATC ATGTGTGTCA ACTACGTCCT GAGTGAGATT 
GAGAAGAATG ACGTGGTGTT CTCCATGGAC CAGACTGAAT CCCTGTTCAA GCCCCACCTG 
ATGGCCATGA ACAGCATCTT TGATAGCAGT GGCAAGGGGG CTGTGTCTGA GAAGAGTAAC 
TTCCTATTCA CCAAGCTAAA GGAGGAGCCC GAGGAGCTGG CCCAGCTGGC TCCCACCCCA 
GGAGACGCCA TCATCTCTCT GGATTTCGGG AATCAGAACT TCGAGGAGTC CTCAGCCTAT 
GGCAAGGCCA TCCTGCCCCC GAGCCAGCCA TGGGCCACGG AGTTGAGGAG CCACAGCACC 
CAGAGCGAGG CTGGGAGCCT GCCTGCCTTC ACCGTGCCCC AGGCAGCTGC CCCGGGCAGC 
ACCACCCCCA GTGCCACCAG CAGCAGCAGC AGCTGCTCCA CGCCCAATAG CCCTGAAGAC 
TATTACACAT CTTTGGATAA CGACCTGAAG ATTGAAGTGA TTGAGAAGCT CTTCGCCATG 
GACACAGAGG CCAAGGACCA ATGCAGTACC CAGACGGATT TCAATGAGCT GGACTTGGAG 
ACACTGGCAC CCTATATCCC CATGGACGGG GAAGACTTCC AGCTAAGCCC CATCTGCCCC 
GAGGAGCGGC TCTTGGCGGA GAACCCACAG TCCACCCCCC AGCACTGCTT CAGTGCCATG 
ACAAACATCT TCCAGCCACT GGCCCCTGTA GCCCCGCACA GTCCCTTCCT CCTGGACAAG 
TTTCAGCAGC AGCTGGAGAG CAAGAAGACA GAGCCCGAGC ACCGGCCCAT GTCCTCCATC 
TTCTTTGATG CCGGAAGCAA AGCATCCCTG CCACCGTGCT GTGGCCAGGC CAGCACCCCT 
CTCTCTTCCA TGGGGGGCAG ATCCAATACC CAGTGGCCCC CAGATCCACC ATTACATTTT 
GGGCCCACAA AGTGGGCCGT CGGGGATCAG CGCACAGAGT TCTTGGGAGC AGCGCCGTTG 
GGGCCCCCTG TCTCTCCACC CCATGTCTCC ACCTTCAAGA CAAGGTCTGC AAAGGGTTTT 
GGGGCTCGAG GCCCAGACGT GCTGAGTCCG GCCATGGTAG CCCTCTCCAA CAAGCTGAAG 
CTGAAGCGAC AGCTGGAGTA TGAAGAGCAA GCCTTCCAGG ACCTGAGCGG GGGGGACCCA 
CCTGGTGGCA GCACCTCACA TTTGATGTGG AAACGGATGA AGAACCTCAG GGGTGGGAGC 
TGCCCTTTGA TGCCGGACAA GCCACTGAGC GCAAATGTAC CCAATGATAA GTTCACCCAA 
AACCCCATGA GGGGCCTGGG CCATCCCCTG AGACATCTGC CGCTGCCACA GCCTCCATCT 
GCCATCAGTC CCGGGGAGAA CAGCAAGAGC AGGTTCCCCC CACAGTGCTA CGCCACCCAG 
TACCAGGACT ACAGCCTGTC GTCAGCCCAC AAGGTGTCAG GCATGGCAAG CCGGCTGCTC 
GGGCCCTCAT TTGAGTCCTA CCTGCTGCCC GAACTGACCA GATATGACTG TGAGGTGAAC 
GTGCCCGTGC TGGGAAGCTC CACGCTCCTG CAAGGAGGGG ACCTCCTCAG AGCCCTGGAC 
CAGGCCACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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Artificial cells, nanomedicine, and biotechnology47(1)1342-1348(2019 Dec)
Zhao D,Wang S,Chu X,Han D

Hypoxia Up-regulates HIF Expression While Suppressing Cell Growth and NOTCH Activity in Leukaemia Cells.
Anticancer research39(8)4165-4170(2019 Aug)
Itoh M,Okuhashi Y,Takahashi Y,Sonoda Y,Mohammad S,Saito T,Shiratori E,Tohda S

Extracellular ATP promotes breast cancer invasion and epithelial-mesenchymal transition via hypoxia-inducible factor 2α signaling.
Cancer science110(8)2456-2470(2019 Aug)
Yang H,Geng YH,Wang P,Zhou YT,Yang H,Huo YF,Zhang HQ,Li Y,He HY,Tian XX,Fang WG

Chiari Malformation Type 1 in
International journal of molecular sciences20(11)(2019 Jun)
Rosenblum JS,Maggio D,Pang Y,Nazari MA,Gonzales MK,Lechan RM,Smirniotopoulos JG,Zhuang Z,Pacak K,Heiss JD

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.
Nature communications10(1)1617(2019 04)
Zou Y,Palte MJ,Deik AA,Li H,Eaton JK,Wang W,Tseng YY,Deasy R,Kost-Alimova M,Dančík V,Leshchiner ES,Viswanathan VS,Signoretti S,Choueiri TK,Boehm JS,Wagner BK,Doench JG,Clish CB,Clemons PA,Schreiber SL

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EPAS1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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