ADH4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADH4
Entrez Gene ID	127
Full Name	alcohol dehydrogenase 4 (class II), pi polypeptide
Synonyms	ADH-2,HEL-S-4
General protein information	Preferred Names alcohol dehydrogenase 4 (class II), pi polypeptide Names alcohol dehydrogenase 4 alcohol dehydrogenase class II pi chain aldehyde reductase epididymis secretory protein Li 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q23
Summary	This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008].
Disorder MIM:	103740

mRNA and Protein(s)

mRNA	Protein	Name
XM_017007714.1	XP_016863203.1	alcohol dehydrogenase 4 isoform X1
NM_001306171.1	NP_001293100.1	all-trans-retinol dehydrogenase [NAD(+)] ADH4 isoform 1
NM_001306172.1	NP_001293101.1	all-trans-retinol dehydrogenase [NAD(+)] ADH4 isoform 1
NM_000670.4	NP_000661.2	all-trans-retinol dehydrogenase [NAD(+)] ADH4 isoform 2
XM_017007713.1	XP_016863202.1	alcohol dehydrogenase 4 isoform X1
XM_017007715.1	XP_016863204.1	alcohol dehydrogenase 4 isoform X2

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os11g0210500	NP_001067485.1
Canis lupus familiaris (dog)	ADH4	XP_535665.2
Mus musculus (house mouse)	Adh4	NP_036126.2
Rattus norvegicus (Norway rat)	Adh4	NP_058966.2
Homo sapiens (human)	ADH4	NP_000661.2
Macaca mulatta (Rhesus monkey)	ADH4	XP_001106068.2
Oryza sativa (rice)	Os11g0210300	NP_001067484.1
Pan troglodytes (chimpanzee)	ADH4	XP_001166445.1
Bos taurus (cattle)	ADH4	NP_001095529.1
Arabidopsis thaliana (thale cress)	ADH1	NP_177837.1
Xenopus tropicalis (tropical clawed frog)	adh4	XP_002934819.1

Gene Ontology
Bibliography

Related articles in PubMed

Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes.
Wang Y, Anderson EP, Tatakis DN
Journal of periodontology(2019 Nov)

Genetic association of HCRTR2, ADH4 and CLOCK genes with cluster headache: a Chinese population-based case-control study.
Fan Z, Hou L, Wan D, Ao R, Zhao D, Yu S
The journal of headache and pain19(1)1(2018 Jan)

Molecular analysis of cluster headache.
Zarrilli F, Tomaiuolo R, Ceglia C, Lombardo B, Izzo B, Castaldo G, Pastore L, De Simone R
The Clinical journal of pain31(1)52-7(2015 Jan)

Impact of alcohol dehydrogenase gene 4 polymorphisms on esophageal squamous cell carcinoma risk in a Chinese population.
Xu X, Wang J, Zhu SM, Yang M, Fang Y, Zhao A, Song Q, Mao W
PloS one10(6)e0127304(2015)

Genetic determinants influencing human serum metabolome among African Americans.
Yu B, Zheng Y, Alexander D, Morrison AC, Coresh J, Boerwinkle E
PLoS genetics10(3)e1004212(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ADH4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADH4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu94890	XM_017007714.1 Latest version!	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu94890	XM_017007713.1 Latest version!	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu94891	XM_017007715.1 Latest version!	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu17356	NM_000670.4 Latest version!	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
OHu56177	NM_001306172.1 Latest version!	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu56177	NM_001306171.1 Latest version!	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADH4 ( XM_017007714.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863203.1 Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu94890
Clone ID Related Accession (Same CDS sequence)	XM_017007714.1 , XM_017007713.1
Accession Version	XM_017007714.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	alcohol dehydrogenase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CTCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCTATA GGAGATCCGA GAACAGTGAC 
TATTCCAAGA CTAAAACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863203.1
CDS	199..1419
Translation	MLVRGPHFELQRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSYRRSENSDYSKTKT

Target ORF information:

RefSeq Version	XM_017007714.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007714.1

ORF Insert Sequence:

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CTCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCTATA GGAGATCCGA GAACAGTGAC 
TATTCCAAGA CTAAAACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADH4 ( XM_017007713.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863202.1 Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu94890
Clone ID Related Accession (Same CDS sequence)	XM_017007714.1 , XM_017007713.1
Accession Version	XM_017007713.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	alcohol dehydrogenase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CTCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCTATA GGAGATCCGA GAACAGTGAC 
TATTCCAAGA CTAAAACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863202.1
CDS	191..1411
Translation	MLVRGPHFELQRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSYRRSENSDYSKTKT

Target ORF information:

RefSeq Version	XM_017007713.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007713.1

ORF Insert Sequence:

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CTCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCTATA GGAGATCCGA GAACAGTGAC 
TATTCCAAGA CTAAAACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADH4 ( XM_017007715.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863204.1 Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu94891
Clone ID Related Accession (Same CDS sequence)	XM_017007715.1
Accession Version	XM_017007715.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	alcohol dehydrogenase 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCACCA AGGGCAAAGT TATTAAATGC AAAGCAGCCA TCGCCTGGGA AGCAGGCAAG 
CCCCTTTGCA TTGAAGAGGT TGAAGTAGCT CCCCCCAAGG CTCATGAAGT TCGCATTCAG 
ATCATTGCTA CCTCTCTGTG CCATACTGAT GCCACTGTTA TCGATTCTAA ATTTGAGGGC 
CTAGCTTTCC CAGTGATCGT TGGCCATGAG GCTGCAGGTA TTGTGGAAAG TATTGGGCCA 
GGAGTGACCA ACGTCAAACC AGGTGACAAA GTAATTCCAC TTTATGCACC TCTATGTAGA 
AAATGCAAGT TTTGTCTGAG TCCACTCACA AATTTGTGTG GGAAAATCAG TAATCTCAAA 
AGTCCTGCTA GTGATCAACA ACTAATGGAA GACAAAACCA GCAGGTTTAC CTGCAAAGGA 
AAACCAGTTT ACCATTTCTT TGGAACCAGT ACATTCTCTC AGTACACTGT GGTGTCAGAT 
ATCAATCTTG CCAAAATAGA TGATGATGCA AATTTAGAGA GAGTTTGTCT GCTTGGATGT 
GGGTTTTCAA CTGGCTATGG GGCTGCAATC AACAATGCCA AGGTCACCCC TGGTTCGACT 
TGTGCTGTCT TTGGCCTAGG AGGTGTGGGT CTTTCTGCTG TAATGGGTTG TAAAGCAGCA 
GGAGCTTCCA GAATCATAGG TATTGACATC AACAGTGAGA AGTTTGTGAA GGCTAAAGCC 
CTGGGAGCCA CTGACTGCCT CAATCCTAGA GACTTACATA AACCGATCCA GGAAGTTATC 
ATTGAATTGA CCAAGGGAGG TGTGGATTTT GCCCTTGACT GTGCAGGTGG ATCTGAAACC 
ATGAAAGCAG CCCTGGACTG TACAACCGCA GGCTGGGGAT CATGTACTTT CATTGGAGTA 
GCTGCTGGTA GCAAAGGATT GACTATTTTT CCAGAGGAGC TAATAATCGG CCGTACTATA 
AATGGAACAT TCTTTGGTGG TTGGAAAAGT GTAGATTCTA TCCCAAAGCT GGTCACTGAC 
TATAAGAATA AGAAATTCAA TCTGGATGCA CTGGTGACCC ATACCCTGCC TTTTGACAAA 
ATCAGTGAGG CATTTGACCT AATGAACCAA GGAAAAAGCT ATAGGAGATC CGAGAACAGT 
GACTATTCCA AGACTAAAAC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863204.1
CDS	109..1272
Translation	MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSYRRSENSDYSKTKT

Target ORF information:

RefSeq Version	XM_017007715.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007715.1

ORF Insert Sequence:

ATGGGCACCA AGGGCAAAGT TATTAAATGC AAAGCAGCCA TCGCCTGGGA AGCAGGCAAG 
CCCCTTTGCA TTGAAGAGGT TGAAGTAGCT CCCCCCAAGG CTCATGAAGT TCGCATTCAG 
ATCATTGCTA CCTCTCTGTG CCATACTGAT GCCACTGTTA TCGATTCTAA ATTTGAGGGC 
CTAGCTTTCC CAGTGATCGT TGGCCATGAG GCTGCAGGTA TTGTGGAAAG TATTGGGCCA 
GGAGTGACCA ACGTCAAACC AGGTGACAAA GTAATTCCAC TTTATGCACC TCTATGTAGA 
AAATGCAAGT TTTGTCTGAG TCCACTCACA AATTTGTGTG GGAAAATCAG TAATCTCAAA 
AGTCCTGCTA GTGATCAACA ACTAATGGAA GACAAAACCA GCAGGTTTAC CTGCAAAGGA 
AAACCAGTTT ACCATTTCTT TGGAACCAGT ACATTCTCTC AGTACACTGT GGTGTCAGAT 
ATCAATCTTG CCAAAATAGA TGATGATGCA AATTTAGAGA GAGTTTGTCT GCTTGGATGT 
GGGTTTTCAA CTGGCTATGG GGCTGCAATC AACAATGCCA AGGTCACCCC TGGTTCGACT 
TGTGCTGTCT TTGGCCTAGG AGGTGTGGGT CTTTCTGCTG TAATGGGTTG TAAAGCAGCA 
GGAGCTTCCA GAATCATAGG TATTGACATC AACAGTGAGA AGTTTGTGAA GGCTAAAGCC 
CTGGGAGCCA CTGACTGCCT CAATCCTAGA GACTTACATA AACCGATCCA GGAAGTTATC 
ATTGAATTGA CCAAGGGAGG TGTGGATTTT GCCCTTGACT GTGCAGGTGG ATCTGAAACC 
ATGAAAGCAG CCCTGGACTG TACAACCGCA GGCTGGGGAT CATGTACTTT CATTGGAGTA 
GCTGCTGGTA GCAAAGGATT GACTATTTTT CCAGAGGAGC TAATAATCGG CCGTACTATA 
AATGGAACAT TCTTTGGTGG TTGGAAAAGT GTAGATTCTA TCCCAAAGCT GGTCACTGAC 
TATAAGAATA AGAAATTCAA TCTGGATGCA CTGGTGACCC ATACCCTGCC TTTTGACAAA 
ATCAGTGAGG CATTTGACCT AATGAACCAA GGAAAAAGCT ATAGGAGATC CGAGAACAGT 
GACTATTCCA AGACTAAAAC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADH4 ( NM_000670.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000661.2 Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 3, mRNA.

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CloneID	OHu17356
Clone ID Related Accession (Same CDS sequence)	NM_000670.4
Accession Version	NM_000670.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574092800000
Organism	Homo sapiens(human)
Product	all-trans-retinol dehydrogenase [NAD(+)] ADH4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AV659364.1, M15943.1, BC022319.1, AK290835.1, EU668317.1, AV658711.1 and AK295556.1. On Apr 16, 2015 this sequence version replaced NM_000670.3. Transcript Variant: This variant (3) differs in the 5' UTR and lacks an exon in the 5' coding region, which results in use of an alternate start codon compared to variant 1. It encodes isoform 2, which is shorter than and has a novel N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU668317.1, M15943.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGCACCA AGGGCAAAGT TATTAAATGC AAAGCAGCCA TCGCCTGGGA AGCAGGCAAG 
CCCCTTTGCA TTGAAGAGGT TGAAGTAGCT CCCCCCAAGG CTCATGAAGT TCGCATTCAG 
ATCATTGCTA CCTCCCTGTG CCATACTGAT GCCACTGTTA TCGATTCTAA ATTTGAGGGC 
CTAGCTTTCC CAGTGATCGT TGGCCATGAG GCTGCAGGTA TTGTGGAAAG TATTGGGCCA 
GGAGTGACCA ACGTCAAACC AGGTGACAAA GTAATTCCAC TTTATGCACC TCTATGTAGA 
AAATGCAAGT TTTGTCTGAG TCCACTCACA AATTTGTGTG GGAAAATCAG TAATCTCAAA 
AGTCCTGCTA GTGATCAACA ACTAATGGAA GACAAAACCA GCAGGTTTAC CTGCAAAGGA 
AAACCAGTTT ACCATTTCTT TGGAACCAGT ACATTCTCTC AGTACACTGT GGTGTCAGAT 
ATCAATCTTG CCAAAATAGA TGATGATGCA AATTTAGAGA GAGTTTGTCT GCTTGGATGT 
GGGTTTTCAA CTGGCTATGG GGCTGCAATC AACAATGCCA AGGTCACCCC TGGTTCGACT 
TGTGCTGTCT TTGGCCTAGG AGGTGTGGGT CTTTCTGCTG TAATGGGTTG TAAAGCAGCA 
GGAGCTTCCA GAATCATAGG TATTGACATC AACAGTGAGA AGTTTGTGAA GGCTAAAGCC 
CTGGGAGCCA CTGACTGCCT CAATCCTAGA GACTTACATA AACCGATCCA GGAAGTTATC 
ATTGAATTGA CCAAGGGAGG TGTGGATTTT GCCCTTGACT GTGCAGGTGG ATCTGAAACC 
ATGAAAGCAG CCCTGGACTG TACAACCGCA GGCTGGGGAT CATGTACTTT CATTGGAGTA 
GCTGCTGGTA GCAAAGGATT GACTATTTTT CCAGAGGAGC TAATAATCGG CCGTACTATA 
AATGGAACAT TCTTTGGTGG TTGGAAAAGT GTAGATTCTA TCCCAAAGCT GGTCACTGAC 
TATAAGAATA AGAAATTCAA TCTGGATGCA CTGGTGACCC ATACCCTGCC TTTTGACAAA 
ATCAGTGAGG CATTTGACCT AATGAACCAA GGAAAAAGCG TCCGAACAAT CCTCATCTTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000661.2
CDS	77..1219
Translation	MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF

Target ORF information:

RefSeq Version	NM_000670.4
Organism	Homo sapiens(human)
Definition	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000670.4

ORF Insert Sequence:

ATGGGCACCA AGGGCAAAGT TATTAAATGC AAAGCAGCCA TCGCCTGGGA AGCAGGCAAG 
CCCCTTTGCA TTGAAGAGGT TGAAGTAGCT CCCCCCAAGG CTCATGAAGT TCGCATTCAG 
ATCATTGCTA CCTCCCTGTG CCATACTGAT GCCACTGTTA TCGATTCTAA ATTTGAGGGC 
CTAGCTTTCC CAGTGATCGT TGGCCATGAG GCTGCAGGTA TTGTGGAAAG TATTGGGCCA 
GGAGTGACCA ACGTCAAACC AGGTGACAAA GTAATTCCAC TTTATGCACC TCTATGTAGA 
AAATGCAAGT TTTGTCTGAG TCCACTCACA AATTTGTGTG GGAAAATCAG TAATCTCAAA 
AGTCCTGCTA GTGATCAACA ACTAATGGAA GACAAAACCA GCAGGTTTAC CTGCAAAGGA 
AAACCAGTTT ACCATTTCTT TGGAACCAGT ACATTCTCTC AGTACACTGT GGTGTCAGAT 
ATCAATCTTG CCAAAATAGA TGATGATGCA AATTTAGAGA GAGTTTGTCT GCTTGGATGT 
GGGTTTTCAA CTGGCTATGG GGCTGCAATC AACAATGCCA AGGTCACCCC TGGTTCGACT 
TGTGCTGTCT TTGGCCTAGG AGGTGTGGGT CTTTCTGCTG TAATGGGTTG TAAAGCAGCA 
GGAGCTTCCA GAATCATAGG TATTGACATC AACAGTGAGA AGTTTGTGAA GGCTAAAGCC 
CTGGGAGCCA CTGACTGCCT CAATCCTAGA GACTTACATA AACCGATCCA GGAAGTTATC 
ATTGAATTGA CCAAGGGAGG TGTGGATTTT GCCCTTGACT GTGCAGGTGG ATCTGAAACC 
ATGAAAGCAG CCCTGGACTG TACAACCGCA GGCTGGGGAT CATGTACTTT CATTGGAGTA 
GCTGCTGGTA GCAAAGGATT GACTATTTTT CCAGAGGAGC TAATAATCGG CCGTACTATA 
AATGGAACAT TCTTTGGTGG TTGGAAAAGT GTAGATTCTA TCCCAAAGCT GGTCACTGAC 
TATAAGAATA AGAAATTCAA TCTGGATGCA CTGGTGACCC ATACCCTGCC TTTTGACAAA 
ATCAGTGAGG CATTTGACCT AATGAACCAA GGAAAAAGCG TCCGAACAAT CCTCATCTTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADH4 ( NM_001306171.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001293100.1 Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu56177
Clone ID Related Accession (Same CDS sequence)	NM_001306171.1 , NM_001306172.1
Accession Version	NM_001306171.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574092800000
Organism	Homo sapiens(human)
Product	all-trans-retinol dehydrogenase [NAD(+)] ADH4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AV659353.1, AK295556.1, EU668317.1, AK290835.1 and AV658711.1. On Apr 16, 2015 this sequence version replaced XM_011531591.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1 and 2 encode isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295556.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CCCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCGTCC GAACAATCCT CATCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001293100.1
CDS	168..1367
Translation	MLVRGPHFELQRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF

Target ORF information:

RefSeq Version	NM_001306171.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001306171.1

ORF Insert Sequence:

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CCCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCGTCC GAACAATCCT CATCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADH4 ( NM_001306172.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001293101.1 Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu56177
Clone ID Related Accession (Same CDS sequence)	NM_001306171.1 , NM_001306172.1
Accession Version	NM_001306172.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574092800000
Organism	Homo sapiens(human)
Product	all-trans-retinol dehydrogenase [NAD(+)] ADH4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AV659353.1, CD014080.1, AK295556.1, EU668317.1, AK290835.1 and AV658711.1. On Apr 16, 2015 this sequence version replaced XM_011531590.1. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR compared to variant 1. Variants 1 and 2 encode isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD014080.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CCCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCGTCC GAACAATCCT CATCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001293101.1
CDS	160..1359
Translation	MLVRGPHFELQRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF

Target ORF information:

RefSeq Version	NM_001306172.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alcohol dehydrogenase 4 (class II), pi polypeptide (ADH4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001306172.1

ORF Insert Sequence:

ATGCTTGTCC GAGGACCACA CTTCGAGTTG CAGAGATGTA AAACACATCT ATTCTCCAGC 
AATTATCTGA CTCAGGTTAT TAAATGCAAA GCAGCCATCG CCTGGGAAGC AGGCAAGCCC 
CTTTGCATTG AAGAGGTTGA AGTAGCTCCC CCCAAGGCTC ATGAAGTTCG CATTCAGATC 
ATTGCTACCT CCCTGTGCCA TACTGATGCC ACTGTTATCG ATTCTAAATT TGAGGGCCTA 
GCTTTCCCAG TGATCGTTGG CCATGAGGCT GCAGGTATTG TGGAAAGTAT TGGGCCAGGA 
GTGACCAACG TCAAACCAGG TGACAAAGTA ATTCCACTTT ATGCACCTCT ATGTAGAAAA 
TGCAAGTTTT GTCTGAGTCC ACTCACAAAT TTGTGTGGGA AAATCAGTAA TCTCAAAAGT 
CCTGCTAGTG ATCAACAACT AATGGAAGAC AAAACCAGCA GGTTTACCTG CAAAGGAAAA 
CCAGTTTACC ATTTCTTTGG AACCAGTACA TTCTCTCAGT ACACTGTGGT GTCAGATATC 
AATCTTGCCA AAATAGATGA TGATGCAAAT TTAGAGAGAG TTTGTCTGCT TGGATGTGGG 
TTTTCAACTG GCTATGGGGC TGCAATCAAC AATGCCAAGG TCACCCCTGG TTCGACTTGT 
GCTGTCTTTG GCCTAGGAGG TGTGGGTCTT TCTGCTGTAA TGGGTTGTAA AGCAGCAGGA 
GCTTCCAGAA TCATAGGTAT TGACATCAAC AGTGAGAAGT TTGTGAAGGC TAAAGCCCTG 
GGAGCCACTG ACTGCCTCAA TCCTAGAGAC TTACATAAAC CGATCCAGGA AGTTATCATT 
GAATTGACCA AGGGAGGTGT GGATTTTGCC CTTGACTGTG CAGGTGGATC TGAAACCATG 
AAAGCAGCCC TGGACTGTAC AACCGCAGGC TGGGGATCAT GTACTTTCAT TGGAGTAGCT 
GCTGGTAGCA AAGGATTGAC TATTTTTCCA GAGGAGCTAA TAATCGGCCG TACTATAAAT 
GGAACATTCT TTGGTGGTTG GAAAAGTGTA GATTCTATCC CAAAGCTGGT CACTGACTAT 
AAGAATAAGA AATTCAATCT GGATGCACTG GTGACCCATA CCCTGCCTTT TGACAAAATC 
AGTGAGGCAT TTGACCTAAT GAACCAAGGA AAAAGCGTCC GAACAATCCT CATCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes.
Journal of periodontology(2019 Nov)
Wang Y,Anderson EP,Tatakis DN

Genetic association of HCRTR2, ADH4 and CLOCK genes with cluster headache: a Chinese population-based case-control study.
The journal of headache and pain19(1)1(2018 Jan)
Fan Z,Hou L,Wan D,Ao R,Zhao D,Yu S

Molecular analysis of cluster headache.
The Clinical journal of pain31(1)52-7(2015 Jan)
Zarrilli F,Tomaiuolo R,Ceglia C,Lombardo B,Izzo B,Castaldo G,Pastore L,De Simone R

Impact of alcohol dehydrogenase gene 4 polymorphisms on esophageal squamous cell carcinoma risk in a Chinese population.
PloS one10(6)e0127304(2015)
Xu X,Wang J,Zhu SM,Yang M,Fang Y,Zhao A,Song Q,Mao W

Genetic determinants influencing human serum metabolome among African Americans.
PLoS genetics10(3)e1004212(2014 Mar)
Yu B,Zheng Y,Alexander D,Morrison AC,Coresh J,Boerwinkle E

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ADH4 cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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