POLR3A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	POLR3A
Entrez Gene ID	11128
Full Name	RNA polymerase III subunit A
Synonyms	ADDH,HLD7,RPC1,RPC155,hRPC155
General protein information	Preferred Names RNA polymerase III subunit A Names DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III largest subunit DNA-directed RNA polymerase III subunit A RNA polymerase III 155 kDa subunit RNA polymerase III subunit C1 RNA polymerase III subunit C160 RNA polymerase III subunit RPC155-D polymerase (RNA) III (DNA directed) polypeptide A, 155kDa polymerase (RNA) III subunit A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q22.3
Summary	The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response. [provided by RefSeq, Aug 2011].
Disorder MIM:	614258
Disorder Html:	Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism, 607694 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_007055.4	NP_008986.2	DNA-directed RNA polymerase III subunit RPC1
NM_007055.3	NP_008986.2	DNA-directed RNA polymerase III subunit RPC1

Pathways from BioSystems

Homologies

Homo sapiens (human)	POLR3A	NP_008986.2
Mus musculus (house mouse)	Polr3a	NP_001074716.1
Gallus gallus (chicken)	POLR3A	NP_001006500.1
Danio rerio (zebrafish)	polr3a	NP_001263425.1
Macaca mulatta (Rhesus monkey)	POLR3A	XP_002805710.1
Bos taurus (cattle)	POLR3A	NP_001077219.1
Caenorhabditis elegans (roundworm)	rpc-1	NP_501127.2
Magnaporthe oryzae (rice blast fungus)	MGG_04477	XP_003710983.1
Oryza sativa (rice)	Os04g0492300	NP_001053175.1
Rattus norvegicus (Norway rat)	Polr3a	XP_341389.5
Drosophila melanogaster (fruit fly)	CG17209	NP_001096987.2
Arabidopsis thaliana (thale cress)	NRPC1	NP_200812.2
Kluyveromyces lactis	KLLA0E21253g	XP_454912.1
Schizosaccharomyces pombe (fission yeast)	rpc1	NP_595506.1
Eremothecium gossypii	AGOS_AER252C	NP_985109.2
Saccharomyces cerevisiae (baker's yeast)	RPO31	NP_014759.1
Xenopus tropicalis (tropical clawed frog)	polr3a	NP_001096178.1
Pan troglodytes (chimpanzee)	POLR3A	XP_507865.4
Canis lupus familiaris (dog)	POLR3A	XP_536399.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004703	XP_318130.4
Neurospora crassa	NCU03986	XP_956571.2

Gene Ontology
Bibliography

Related articles in PubMed

Specific combinations of biallelic
Paolacci S, Li Y, Agolini E, Bellacchio E, Arboleda-Bustos CE, Carrero D, Bertola D, Al-Gazali L, Alders M, Altmüller J, Arboleda G, Beleggia F, Bruselles A, Ciolfi A, Gillessen-Kaesbach G, Krieg T, Mohammed S, Müller C, Novelli A, Ortega J, Sandoval A, Velasco G, Yigit G, Arboleda H, Lopez-Otin C, Wollnik B, Tartaglia M, Hennekam RC
Journal of medical genetics55(12)837-846(2018 12)

Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations.
Lessel D, Ozel AB, Campbell SE, Saadi A, Arlt MF, McSweeney KM, Plaiasu V, Szakszon K, Szőllős A, Rusu C, Rojas AJ, Lopez-Valdez J, Thiele H, Nürnberg P, Nickerson DA, Bamshad MJ, Li JZ, Kubisch C, Glover TW, Gordon LB
Human genetics137(11-12)921-939(2018 Dec)

Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome.
Wambach JA, Wegner DJ, Patni N, Kircher M, Willing MC, Baldridge D, Xing C, Agarwal AK, Vergano SAS, Patel C, Grange DK, Kenney A, Najaf T, Nickerson DA, Bamshad MJ, Cole FS, Garg A
American journal of human genetics103(6)968-975(2018 12)

RNA Polymerase III as a Gatekeeper to Prevent Severe VZV Infections.
Carter-Timofte ME, Paludan SR, Mogensen TH
Trends in molecular medicine24(10)904-915(2018 10)

Epigenetic regulation of RNA polymerase III transcription in early breast tumorigenesis.
Park JL, Lee YS, Song MJ, Hong SH, Ahn JH, Seo EH, Shin SP, Lee SJ, Johnson BH, Stampfer MR, Kim HP, Kim SY, Lee YS
Oncogene36(49)6793-6804(2017 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following POLR3A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POLR3A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27038	NM_007055.4 Latest version!	Homo sapiens RNA polymerase III subunit A (POLR3A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$384.30 $549.00
View Old Accession Versions >>
OHu27038	NM_007055.3	Homo sapiens RNA polymerase III subunit A (POLR3A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$384.30 $549.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POLR3A ( NM_007055.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_008986.2 Homo sapiens RNA polymerase III subunit A (POLR3A), mRNA.

Price & Availability↑

CloneID	OHu27038
Clone ID Related Accession (Same CDS sequence)	NM_007055.4 , NM_007055.3
Accession Version	NM_007055.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574006400000
Organism	Homo sapiens(human)
Product	DNA-directed RNA polymerase III subunit RPC1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA103416.1, AY091459.1, BC041089.1, AK024744.1, DA353439.1 and CA449326.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_007055.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.40301.1, SRR1660809.11944.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372371.8/ ENSP00000361446.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGAAGG AGCAGTTCCG GGAGACGGAT GTGGCCAAGA AAATAAGCCA CATCTGTTTT 
GGAATGAAGT CACCTGAGGA GATGCGCCAG CAGGCGCACA TCCAAGTTGT GAGTAAGAAC 
CTGTACAGCC AGGACAACCA ACATGCCCCC TTGCTATATG GGGTGCTCGA CCATAGGATG 
GGTACGAGTG AGAAGGATCG TCCATGTGAA ACCTGTGGGA AAAACTTGGC TGACTGTCTA 
GGCCACTATG GGTATATCGA CCTGGAGTTG CCGTGTTTTC ATGTAGGGTA CTTCAGAGCA 
GTCATAGGCA TCTTACAGAT GATCTGCAAA ACCTGCTGCC ACATCATGCT GTCCCAAGAG 
GAGAAGAAGC AGTTTCTGGA CTATCTAAAG AGGCCCGGCC TGACCTACCT TCAGAAGCGA 
GGACTGAAAA AGAAAATCTC TGACAAGTGC CGGAAGAAAA ACATCTGCCA TCACTGTGGC 
GCTTTTAATG GTACCGTAAA GAAGTGTGGA CTGCTGAAAA TAATTCATGA GAAATACAAG 
ACCAACAAAA AAGTGGTGGA TCCCATTGTA TCAAATTTCC TTCAGTCTTT TGAAACAGCC 
ATTGAACATA ATAAAGAAGT GGAGCCTCTG CTGGGAAGGG CACAGGAAAA CTTGAATCCC 
TTAGTAGTTC TGAATTTATT TAAACGAATC CCAGCTGAAG ATGTTCCTCT ACTTCTGATG 
AACCCAGAAG CCGGAAAGCC GTCTGATTTG ATTCTCACAC GACTTTTGGT GCCTCCTTTG 
TGTATCAGAC CCTCCGTTGT GAGTGATTTG AAGTCTGGCA CCAATGAAGA TGATCTGACA 
ATGAAACTGA CAGAAATCAT TTTCCTAAAC GATGTTATTA AAAAGCATCG GATCTCAGGA 
GCCAAGACCC AGATGATCAT GGAGGACTGG GATTTCCTGC AGCTGCAGTG TGCCCTCTAC 
ATTAACAGTG AGCTCTCGGG CATTCCCCTC AACATGGCAC CCAAGAAGTG GACCAGAGGC 
TTCGTCCAAC GCCTGAAGGG AAAACAGGGT CGATTTAGAG GAAATCTCTC AGGAAAGAGA 
GTGGATTTTT CTGGCAGAAC AGTCATCTCG CCCGACCCCA ACCTCCGGAT TGATGAGGTA 
GCTGTGCCAG TTCATGTGGC CAAAATTCTA ACTTTTCCTG AGAAGGTAAA CAAAGCAAAC 
ATCAATTTCT TGAGGAAACT GGTTCAAAAC GGCCCTGAGG TTCACCCAGG AGCAAACTTC 
ATTCAGCAGA GACATACGCA GATGAAAAGG TTTTTGAAAT ACGGAAATCG AGAAAAGATG 
GCTCAAGAGC TCAAGTATGG TGACATCGTA GAGAGACACC TCATCGATGG AGATGTGGTG 
CTGTTCAATC GGCAGCCCTC GCTGCACAAA TTGAGCATTA TGGCTCATCT GGCCAGGGTC 
AAGCCCCACC GGACCTTCAG ATTTAATGAG TGTGTCTGTA CACCCTATAA TGCTGACTTT 
GATGGTGATG AAATGAACCT TCATCTTCCT CAAACAGAAG AAGCTAAAGC AGAGGCCCTT 
GTTCTGATGG GGACTAAAGC AAATCTTGTA ACCCCGAGGA ATGGGGAACC GCTGATTGCT 
GCTATTCAGG ATTTTCTAAC AGGTGCCTAT CTCCTCACTC TCAAGGACAC TTTCTTTGAT 
CGAGCCAAGG CTTGCCAAAT CATTGCTTCA ATACTGGTTG GCAAGGATGA GAAAATTAAA 
GTTCGCCTCC CACCGCCTAC AATCCTAAAG CCTGTCACCC TGTGGACGGG AAAGCAGATC 
TTCAGTGTCA TCCTCAGGCC TAGCGATGAC AATCCAGTGA GGGCCAACCT GCGAACCAAG 
GGCAAGCAGT ACTGTGGCAA AGGGGAAGAT CTCTGTGCCA ATGATTCCTA TGTTACAATC 
CAGAACAGTG AGTTGATGAG TGGCAGCATG GACAAAGGAA CCCTAGGGTC AGGATCCAAG 
AACAATATTT TTTACATTTT GCTGCGAGAC TGGGGACAGA ATGAAGCTGC AGATGCCATG 
TCACGGCTCG CCAGGCTGGC TCCTGTCTAC CTGTCTAACC GTGGTTTCTC AATTGGGATC 
GGTGATGTCA CACCTGGCCA AGGACTGCTG AAGGCCAAGT ATGAGTTGCT GAATGCCGGC 
TACAAGAAAT GTGATGAGTA CATCGAAGCC CTGAACACGG GCAAGCTGCA GCAGCAGCCT 
GGCTGCACTG CTGAGGAGAC CCTGGAGGCA CTGATCCTGA AGGAGCTGTC TGTGATCCGT 
GACCACGCTG GCAGTGCCTG CCTCCGGGAG CTGGACAAGA GCAACAGCCC CCTCACCATG 
GCTCTGTGCG GCTCCAAAGG TTCCTTCATT AACATATCAC AGATGATTGC CTGTGTGGGA 
CAGCAGGCCA TCAGTGGCTC TCGAGTGCCA GACGGCTTTG AAAACAGGTC CTTGCCTCAT 
TTTGAAAAAC ACTCAAAGCT CCCAGCTGCC AAAGGCTTTG TGGCTAATAG CTTTTATTCC 
GGTTTGACAC CAACTGAGTT TTTCTTCCAC ACAATGGCCG GCCGGGAAGG TCTAGTCGAC 
ACGGCTGTAA AGACAGCTGA AACGGGATAC ATGCAGCGAA GGCTTGTCAA ATCTCTTGAA 
GATCTTTGCT CCCAGTATGA TCTGACAGTC CGAAGCTCTA CTGGCGATAT TATCCAGTTC 
ATTTATGGAG GAGATGGCTT AGATCCTGCA GCTATGGAGG GAAAAGATGA ACCTTTGGAG 
TTTAAAAGGG TTCTGGACAA CATCAAAGCA GTCTTCCCGT GTCCCAGTGA GCCTGCTCTC 
AGCAAAAACG AGCTGATCCT GACCACAGAG TCCATCATGA AGAAGAGTGA GTTCCTCTGC 
TGCCAGGACA GCTTCCTGCA GGAAATAAAA AAATTCATTA AGGGGGTCTC TGAGAAGATC 
AAGAAAACCA GAGATAAATA TGGCATCAAT GATAACGGCA CAACAGAGCC CCGTGTGCTG 
TACCAGCTGG ACCGCATCAC CCCCACCCAA GTAGAAAAGT TTCTGGAGAC CTGTAGGGAC 
AAGTACATGA GGGCACAGAT GGAGCCAGGT TCTGCAGTGG GTGCTCTGTG TGCCCAGAGC 
ATTGGTGAGC CAGGCACCCA GATGACCCTG AAGACTTTCC ACTTTGCAGG TGTGGCCTCC 
ATGAACATCA CCCTGGGCGT GCCCCGGATT AAAGAGATCA TCAACGCTTC CAAGGCCATC 
AGCACTCCAA TTATCACAGC ACAGCTAGAC AAGGATGACG ACGCGGATTA TGCTCGCCTC 
GTGAAAGGGA GAATTGAGAA AACCCTCTTG GGAGAGATTT CCGAGTATAT TGAAGAAGTG 
TTTCTTCCTG ATGACTGCTT TATTCTCGTC AAGCTCTCCC TGGAACGGAT TAGGCTTCTG 
AGACTGGAAG TGAACGCTGA GACAGTGAGA TATTCCATCT GCACATCCAA GCTCCGTGTG 
AAGCCCGGTG ATGTGGCTGT TCATGGTGAG GCTGTGGTGT GTGTCACCCC CAGAGAGAAC 
AGCAAGAGCT CCATGTACTA CGTGCTGCAG TTCCTGAAAG AGGATCTCCC CAAGGTGGTG 
GTGCAGGGCA TTCCAGAGGT GTCCAGAGCT GTCATCCACA TTGACGAGCA GAGTGGAAAG 
GAGAAGTACA AGCTTCTGGT GGAAGGTGAT AACCTGCGGG CAGTCATGGC CACACACGGT 
GTGAAGGGCA CCCGAACCAC CTCCAATAAC ACCTATGAGG TGGAGAAAAC TCTGGGCATC 
GAGGCCGCCC GGACAACGAT CATCAATGAA ATCCAGTACA CCATGGTGAA CCACGGCATG 
AGCATCGACA GGAGGCACGT GATGCTGCTC TCCGACCTCA TGACCTACAA GGGTGAAGTC 
CTGGGCATCA CTAGGTTTGG CCTGGCCAAG ATGAAGGAGA GTGTGCTGAT GCTGGCCTCC 
TTTGAGAAGA CGGCTGACCA TCTCTTTGAC GCTGCCTACT TCGGGCAGAA GGACTCTGTG 
TGTGGGGTGT CTGAGTGCAT CATCATGGGA ATCCCAATGA ACATTGGAAC CGGGCTCTTC 
AAGCTGCTTC ACAAGGCTGA CAGGGACCCG AACCCTCCCA AGAGGCCCCT GATCTTCGAC 
ACAAATGAAT TCCACATCCC CCTTGTCACA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008986.2
CDS	109..4281
Translation	MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQEEKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDVPLLLMNPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANFIQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLCCQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLLRLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPLIFDTNEFHIPLVT

Target ORF information:

RefSeq Version	NM_007055.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA polymerase III subunit A (POLR3A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007055.4

ORF Insert Sequence:

ATGGTGAAGG AGCAGTTCCG GGAGACGGAT GTGGCCAAGA AAATAAGCCA CATCTGTTTT 
GGAATGAAGT CACCTGAGGA GATGCGCCAG CAGGCGCACA TCCAAGTTGT GAGTAAGAAC 
CTGTACAGCC AGGACAACCA ACATGCCCCC TTGCTATATG GGGTGCTCGA CCATAGGATG 
GGTACGAGTG AGAAGGATCG TCCATGTGAA ACCTGTGGGA AAAACTTGGC TGACTGTCTA 
GGCCACTATG GGTATATCGA CCTGGAGTTG CCGTGTTTTC ATGTAGGGTA CTTCAGAGCA 
GTCATAGGCA TCTTACAGAT GATCTGCAAA ACCTGCTGCC ACATCATGCT GTCCCAAGAG 
GAGAAGAAGC AGTTTCTGGA CTATCTAAAG AGGCCCGGCC TGACCTACCT TCAGAAGCGA 
GGACTGAAAA AGAAAATCTC TGACAAGTGC CGGAAGAAAA ACATCTGCCA TCACTGTGGC 
GCTTTTAATG GTACCGTAAA GAAGTGTGGA CTGCTGAAAA TAATTCATGA GAAATACAAG 
ACCAACAAAA AAGTGGTGGA TCCCATTGTA TCAAATTTCC TTCAGTCTTT TGAAACAGCC 
ATTGAACATA ATAAAGAAGT GGAGCCTCTG CTGGGAAGGG CACAGGAAAA CTTGAATCCC 
TTAGTAGTTC TGAATTTATT TAAACGAATC CCAGCTGAAG ATGTTCCTCT ACTTCTGATG 
AACCCAGAAG CCGGAAAGCC GTCTGATTTG ATTCTCACAC GACTTTTGGT GCCTCCTTTG 
TGTATCAGAC CCTCCGTTGT GAGTGATTTG AAGTCTGGCA CCAATGAAGA TGATCTGACA 
ATGAAACTGA CAGAAATCAT TTTCCTAAAC GATGTTATTA AAAAGCATCG GATCTCAGGA 
GCCAAGACCC AGATGATCAT GGAGGACTGG GATTTCCTGC AGCTGCAGTG TGCCCTCTAC 
ATTAACAGTG AGCTCTCGGG CATTCCCCTC AACATGGCAC CCAAGAAGTG GACCAGAGGC 
TTCGTCCAAC GCCTGAAGGG AAAACAGGGT CGATTTAGAG GAAATCTCTC AGGAAAGAGA 
GTGGATTTTT CTGGCAGAAC AGTCATCTCG CCCGACCCCA ACCTCCGGAT TGATGAGGTA 
GCTGTGCCAG TTCATGTGGC CAAAATTCTA ACTTTTCCTG AGAAGGTAAA CAAAGCAAAC 
ATCAATTTCT TGAGGAAACT GGTTCAAAAC GGCCCTGAGG TTCACCCAGG AGCAAACTTC 
ATTCAGCAGA GACATACGCA GATGAAAAGG TTTTTGAAAT ACGGAAATCG AGAAAAGATG 
GCTCAAGAGC TCAAGTATGG TGACATCGTA GAGAGACACC TCATCGATGG AGATGTGGTG 
CTGTTCAATC GGCAGCCCTC GCTGCACAAA TTGAGCATTA TGGCTCATCT GGCCAGGGTC 
AAGCCCCACC GGACCTTCAG ATTTAATGAG TGTGTCTGTA CACCCTATAA TGCTGACTTT 
GATGGTGATG AAATGAACCT TCATCTTCCT CAAACAGAAG AAGCTAAAGC AGAGGCCCTT 
GTTCTGATGG GGACTAAAGC AAATCTTGTA ACCCCGAGGA ATGGGGAACC GCTGATTGCT 
GCTATTCAGG ATTTTCTAAC AGGTGCCTAT CTCCTCACTC TCAAGGACAC TTTCTTTGAT 
CGAGCCAAGG CTTGCCAAAT CATTGCTTCA ATACTGGTTG GCAAGGATGA GAAAATTAAA 
GTTCGCCTCC CACCGCCTAC AATCCTAAAG CCTGTCACCC TGTGGACGGG AAAGCAGATC 
TTCAGTGTCA TCCTCAGGCC TAGCGATGAC AATCCAGTGA GGGCCAACCT GCGAACCAAG 
GGCAAGCAGT ACTGTGGCAA AGGGGAAGAT CTCTGTGCCA ATGATTCCTA TGTTACAATC 
CAGAACAGTG AGTTGATGAG TGGCAGCATG GACAAAGGAA CCCTAGGGTC AGGATCCAAG 
AACAATATTT TTTACATTTT GCTGCGAGAC TGGGGACAGA ATGAAGCTGC AGATGCCATG 
TCACGGCTCG CCAGGCTGGC TCCTGTCTAC CTGTCTAACC GTGGTTTCTC AATTGGGATC 
GGTGATGTCA CACCTGGCCA AGGACTGCTG AAGGCCAAGT ATGAGTTGCT GAATGCCGGC 
TACAAGAAAT GTGATGAGTA CATCGAAGCC CTGAACACGG GCAAGCTGCA GCAGCAGCCT 
GGCTGCACTG CTGAGGAGAC CCTGGAGGCA CTGATCCTGA AGGAGCTGTC TGTGATCCGT 
GACCACGCTG GCAGTGCCTG CCTCCGGGAG CTGGACAAGA GCAACAGCCC CCTCACCATG 
GCTCTGTGCG GCTCCAAAGG TTCCTTCATT AACATATCAC AGATGATTGC CTGTGTGGGA 
CAGCAGGCCA TCAGTGGCTC TCGAGTGCCA GACGGCTTTG AAAACAGGTC CTTGCCTCAT 
TTTGAAAAAC ACTCAAAGCT CCCAGCTGCC AAAGGCTTTG TGGCTAATAG CTTTTATTCC 
GGTTTGACAC CAACTGAGTT TTTCTTCCAC ACAATGGCCG GCCGGGAAGG TCTAGTCGAC 
ACGGCTGTAA AGACAGCTGA AACGGGATAC ATGCAGCGAA GGCTTGTCAA ATCTCTTGAA 
GATCTTTGCT CCCAGTATGA TCTGACAGTC CGAAGCTCTA CTGGCGATAT TATCCAGTTC 
ATTTATGGAG GAGATGGCTT AGATCCTGCA GCTATGGAGG GAAAAGATGA ACCTTTGGAG 
TTTAAAAGGG TTCTGGACAA CATCAAAGCA GTCTTCCCGT GTCCCAGTGA GCCTGCTCTC 
AGCAAAAACG AGCTGATCCT GACCACAGAG TCCATCATGA AGAAGAGTGA GTTCCTCTGC 
TGCCAGGACA GCTTCCTGCA GGAAATAAAA AAATTCATTA AGGGGGTCTC TGAGAAGATC 
AAGAAAACCA GAGATAAATA TGGCATCAAT GATAACGGCA CAACAGAGCC CCGTGTGCTG 
TACCAGCTGG ACCGCATCAC CCCCACCCAA GTAGAAAAGT TTCTGGAGAC CTGTAGGGAC 
AAGTACATGA GGGCACAGAT GGAGCCAGGT TCTGCAGTGG GTGCTCTGTG TGCCCAGAGC 
ATTGGTGAGC CAGGCACCCA GATGACCCTG AAGACTTTCC ACTTTGCAGG TGTGGCCTCC 
ATGAACATCA CCCTGGGCGT GCCCCGGATT AAAGAGATCA TCAACGCTTC CAAGGCCATC 
AGCACTCCAA TTATCACAGC ACAGCTAGAC AAGGATGACG ACGCGGATTA TGCTCGCCTC 
GTGAAAGGGA GAATTGAGAA AACCCTCTTG GGAGAGATTT CCGAGTATAT TGAAGAAGTG 
TTTCTTCCTG ATGACTGCTT TATTCTCGTC AAGCTCTCCC TGGAACGGAT TAGGCTTCTG 
AGACTGGAAG TGAACGCTGA GACAGTGAGA TATTCCATCT GCACATCCAA GCTCCGTGTG 
AAGCCCGGTG ATGTGGCTGT TCATGGTGAG GCTGTGGTGT GTGTCACCCC CAGAGAGAAC 
AGCAAGAGCT CCATGTACTA CGTGCTGCAG TTCCTGAAAG AGGATCTCCC CAAGGTGGTG 
GTGCAGGGCA TTCCAGAGGT GTCCAGAGCT GTCATCCACA TTGACGAGCA GAGTGGAAAG 
GAGAAGTACA AGCTTCTGGT GGAAGGTGAT AACCTGCGGG CAGTCATGGC CACACACGGT 
GTGAAGGGCA CCCGAACCAC CTCCAATAAC ACCTATGAGG TGGAGAAAAC TCTGGGCATC 
GAGGCCGCCC GGACAACGAT CATCAATGAA ATCCAGTACA CCATGGTGAA CCACGGCATG 
AGCATCGACA GGAGGCACGT GATGCTGCTC TCCGACCTCA TGACCTACAA GGGTGAAGTC 
CTGGGCATCA CTAGGTTTGG CCTGGCCAAG ATGAAGGAGA GTGTGCTGAT GCTGGCCTCC 
TTTGAGAAGA CGGCTGACCA TCTCTTTGAC GCTGCCTACT TCGGGCAGAA GGACTCTGTG 
TGTGGGGTGT CTGAGTGCAT CATCATGGGA ATCCCAATGA ACATTGGAAC CGGGCTCTTC 
AAGCTGCTTC ACAAGGCTGA CAGGGACCCG AACCCTCCCA AGAGGCCCCT GATCTTCGAC 
ACAAATGAAT TCCACATCCC CCTTGTCACA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POLR3A ( NM_007055.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_008986.2 Homo sapiens RNA polymerase III subunit A (POLR3A), mRNA.

Price & Availability↑

CloneID	OHu27038
Clone ID Related Accession (Same CDS sequence)	NM_007055.4 , NM_007055.3
Accession Version	NM_007055.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514390400000
Organism	Homo sapiens(human)
Product	DNA-directed RNA polymerase III subunit RPC1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA103416.1, AY091459.1, BC041089.1, AK024744.1, DA353439.1 and CA449326.1. This sequence is a reference standard in the RefSeqGene project. On May 13, 2010 this sequence version replaced NM_007055.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.40301.1, SRR1660809.11944.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGAAGG AGCAGTTCCG GGAGACGGAT GTGGCCAAGA AAATAAGCCA CATCTGTTTT 
GGAATGAAGT CACCTGAGGA GATGCGCCAG CAGGCGCACA TCCAAGTTGT GAGTAAGAAC 
CTGTACAGCC AGGACAACCA ACATGCCCCC TTGCTATATG GGGTGCTCGA CCATAGGATG 
GGTACGAGTG AGAAGGATCG TCCATGTGAA ACCTGTGGGA AAAACTTGGC TGACTGTCTA 
GGCCACTATG GGTATATCGA CCTGGAGTTG CCGTGTTTTC ATGTAGGGTA CTTCAGAGCA 
GTCATAGGCA TCTTACAGAT GATCTGCAAA ACCTGCTGCC ACATCATGCT GTCCCAAGAG 
GAGAAGAAGC AGTTTCTGGA CTATCTAAAG AGGCCCGGCC TGACCTACCT TCAGAAGCGA 
GGACTGAAAA AGAAAATCTC TGACAAGTGC CGGAAGAAAA ACATCTGCCA TCACTGTGGC 
GCTTTTAATG GTACCGTAAA GAAGTGTGGA CTGCTGAAAA TAATTCATGA GAAATACAAG 
ACCAACAAAA AAGTGGTGGA TCCCATTGTA TCAAATTTCC TTCAGTCTTT TGAAACAGCC 
ATTGAACATA ATAAAGAAGT GGAGCCTCTG CTGGGAAGGG CACAGGAAAA CTTGAATCCC 
TTAGTAGTTC TGAATTTATT TAAACGAATC CCAGCTGAAG ATGTTCCTCT ACTTCTGATG 
AACCCAGAAG CCGGAAAGCC GTCTGATTTG ATTCTCACAC GACTTTTGGT GCCTCCTTTG 
TGTATCAGAC CCTCCGTTGT GAGTGATTTG AAGTCTGGCA CCAATGAAGA TGATCTGACA 
ATGAAACTGA CAGAAATCAT TTTCCTAAAC GATGTTATTA AAAAGCATCG GATCTCAGGA 
GCCAAGACCC AGATGATCAT GGAGGACTGG GATTTCCTGC AGCTGCAGTG TGCCCTCTAC 
ATTAACAGTG AGCTCTCGGG CATTCCCCTC AACATGGCAC CCAAGAAGTG GACCAGAGGC 
TTCGTCCAAC GCCTGAAGGG AAAACAGGGT CGATTTAGAG GAAATCTCTC AGGAAAGAGA 
GTGGATTTTT CTGGCAGAAC AGTCATCTCG CCCGACCCCA ACCTCCGGAT TGATGAGGTA 
GCTGTGCCAG TTCATGTGGC CAAAATTCTA ACTTTTCCTG AGAAGGTAAA CAAAGCAAAC 
ATCAATTTCT TGAGGAAACT GGTTCAAAAC GGCCCTGAGG TTCACCCAGG AGCAAACTTC 
ATTCAGCAGA GACATACGCA GATGAAAAGG TTTTTGAAAT ACGGAAATCG AGAAAAGATG 
GCTCAAGAGC TCAAGTATGG TGACATCGTA GAGAGACACC TCATCGATGG AGATGTGGTG 
CTGTTCAATC GGCAGCCCTC GCTGCACAAA TTGAGCATTA TGGCTCATCT GGCCAGGGTC 
AAGCCCCACC GGACCTTCAG ATTTAATGAG TGTGTCTGTA CACCCTATAA TGCTGACTTT 
GATGGTGATG AAATGAACCT TCATCTTCCT CAAACAGAAG AAGCTAAAGC AGAGGCCCTT 
GTTCTGATGG GGACTAAAGC AAATCTTGTA ACCCCGAGGA ATGGGGAACC GCTGATTGCT 
GCTATTCAGG ATTTTCTAAC AGGTGCCTAT CTCCTCACTC TCAAGGACAC TTTCTTTGAT 
CGAGCCAAGG CTTGCCAAAT CATTGCTTCA ATACTGGTTG GCAAGGATGA GAAAATTAAA 
GTTCGCCTCC CACCGCCTAC AATCCTAAAG CCTGTCACCC TGTGGACGGG AAAGCAGATC 
TTCAGTGTCA TCCTCAGGCC TAGCGATGAC AATCCAGTGA GGGCCAACCT GCGAACCAAG 
GGCAAGCAGT ACTGTGGCAA AGGGGAAGAT CTCTGTGCCA ATGATTCCTA TGTTACAATC 
CAGAACAGTG AGTTGATGAG TGGCAGCATG GACAAAGGAA CCCTAGGGTC AGGATCCAAG 
AACAATATTT TTTACATTTT GCTGCGAGAC TGGGGACAGA ATGAAGCTGC AGATGCCATG 
TCACGGCTCG CCAGGCTGGC TCCTGTCTAC CTGTCTAACC GTGGTTTCTC AATTGGGATC 
GGTGATGTCA CACCTGGCCA AGGACTGCTG AAGGCCAAGT ATGAGTTGCT GAATGCCGGC 
TACAAGAAAT GTGATGAGTA CATCGAAGCC CTGAACACGG GCAAGCTGCA GCAGCAGCCT 
GGCTGCACTG CTGAGGAGAC CCTGGAGGCA CTGATCCTGA AGGAGCTGTC TGTGATCCGT 
GACCACGCTG GCAGTGCCTG CCTCCGGGAG CTGGACAAGA GCAACAGCCC CCTCACCATG 
GCTCTGTGCG GCTCCAAAGG TTCCTTCATT AACATATCAC AGATGATTGC CTGTGTGGGA 
CAGCAGGCCA TCAGTGGCTC TCGAGTGCCA GACGGCTTTG AAAACAGGTC CTTGCCTCAT 
TTTGAAAAAC ACTCAAAGCT CCCAGCTGCC AAAGGCTTTG TGGCTAATAG CTTTTATTCC 
GGTTTGACAC CAACTGAGTT TTTCTTCCAC ACAATGGCCG GCCGGGAAGG TCTAGTCGAC 
ACGGCTGTAA AGACAGCTGA AACGGGATAC ATGCAGCGAA GGCTTGTCAA ATCTCTTGAA 
GATCTTTGCT CCCAGTATGA TCTGACAGTC CGAAGCTCTA CTGGCGATAT TATCCAGTTC 
ATTTATGGAG GAGATGGCTT AGATCCTGCA GCTATGGAGG GAAAAGATGA ACCTTTGGAG 
TTTAAAAGGG TTCTGGACAA CATCAAAGCA GTCTTCCCGT GTCCCAGTGA GCCTGCTCTC 
AGCAAAAACG AGCTGATCCT GACCACAGAG TCCATCATGA AGAAGAGTGA GTTCCTCTGC 
TGCCAGGACA GCTTCCTGCA GGAAATAAAA AAATTCATTA AGGGGGTCTC TGAGAAGATC 
AAGAAAACCA GAGATAAATA TGGCATCAAT GATAACGGCA CAACAGAGCC CCGTGTGCTG 
TACCAGCTGG ACCGCATCAC CCCCACCCAA GTAGAAAAGT TTCTGGAGAC CTGTAGGGAC 
AAGTACATGA GGGCACAGAT GGAGCCAGGT TCTGCAGTGG GTGCTCTGTG TGCCCAGAGC 
ATTGGTGAGC CAGGCACCCA GATGACCCTG AAGACTTTCC ACTTTGCAGG TGTGGCCTCC 
ATGAACATCA CCCTGGGCGT GCCCCGGATT AAAGAGATCA TCAACGCTTC CAAGGCCATC 
AGCACTCCAA TTATCACAGC ACAGCTAGAC AAGGATGACG ACGCGGATTA TGCTCGCCTC 
GTGAAAGGGA GAATTGAGAA AACCCTCTTG GGAGAGATTT CCGAGTATAT TGAAGAAGTG 
TTTCTTCCTG ATGACTGCTT TATTCTCGTC AAGCTCTCCC TGGAACGGAT TAGGCTTCTG 
AGACTGGAAG TGAACGCTGA GACAGTGAGA TATTCCATCT GCACATCCAA GCTCCGTGTG 
AAGCCCGGTG ATGTGGCTGT TCATGGTGAG GCTGTGGTGT GTGTCACCCC CAGAGAGAAC 
AGCAAGAGCT CCATGTACTA CGTGCTGCAG TTCCTGAAAG AGGATCTCCC CAAGGTGGTG 
GTGCAGGGCA TTCCAGAGGT GTCCAGAGCT GTCATCCACA TTGACGAGCA GAGTGGAAAG 
GAGAAGTACA AGCTTCTGGT GGAAGGTGAT AACCTGCGGG CAGTCATGGC CACACACGGT 
GTGAAGGGCA CCCGAACCAC CTCCAATAAC ACCTATGAGG TGGAGAAAAC TCTGGGCATC 
GAGGCCGCCC GGACAACGAT CATCAATGAA ATCCAGTACA CCATGGTGAA CCACGGCATG 
AGCATCGACA GGAGGCACGT GATGCTGCTC TCCGACCTCA TGACCTACAA GGGTGAAGTC 
CTGGGCATCA CTAGGTTTGG CCTGGCCAAG ATGAAGGAGA GTGTGCTGAT GCTGGCCTCC 
TTTGAGAAGA CGGCTGACCA TCTCTTTGAC GCTGCCTACT TCGGGCAGAA GGACTCTGTG 
TGTGGGGTGT CTGAGTGCAT CATCATGGGA ATCCCAATGA ACATTGGAAC CGGGCTCTTC 
AAGCTGCTTC ACAAGGCTGA CAGGGACCCG AACCCTCCCA AGAGGCCCCT GATCTTCGAC 
ACAAATGAAT TCCACATCCC CCTTGTCACA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008986.2
CDS	134..4306
Translation	MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQEEKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDVPLLLMNPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANFIQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLCCQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRDKYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAISTPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLLRLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPLIFDTNEFHIPLVT

Target ORF information:

RefSeq Version	NM_007055.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA polymerase III subunit A (POLR3A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007055.3

ORF Insert Sequence:

ATGGTGAAGG AGCAGTTCCG GGAGACGGAT GTGGCCAAGA AAATAAGCCA CATCTGTTTT 
GGAATGAAGT CACCTGAGGA GATGCGCCAG CAGGCGCACA TCCAAGTTGT GAGTAAGAAC 
CTGTACAGCC AGGACAACCA ACATGCCCCC TTGCTATATG GGGTGCTCGA CCATAGGATG 
GGTACGAGTG AGAAGGATCG TCCATGTGAA ACCTGTGGGA AAAACTTGGC TGACTGTCTA 
GGCCACTATG GGTATATCGA CCTGGAGTTG CCGTGTTTTC ATGTAGGGTA CTTCAGAGCA 
GTCATAGGCA TCTTACAGAT GATCTGCAAA ACCTGCTGCC ACATCATGCT GTCCCAAGAG 
GAGAAGAAGC AGTTTCTGGA CTATCTAAAG AGGCCCGGCC TGACCTACCT TCAGAAGCGA 
GGACTGAAAA AGAAAATCTC TGACAAGTGC CGGAAGAAAA ACATCTGCCA TCACTGTGGC 
GCTTTTAATG GTACCGTAAA GAAGTGTGGA CTGCTGAAAA TAATTCATGA GAAATACAAG 
ACCAACAAAA AAGTGGTGGA TCCCATTGTA TCAAATTTCC TTCAGTCTTT TGAAACAGCC 
ATTGAACATA ATAAAGAAGT GGAGCCTCTG CTGGGAAGGG CACAGGAAAA CTTGAATCCC 
TTAGTAGTTC TGAATTTATT TAAACGAATC CCAGCTGAAG ATGTTCCTCT ACTTCTGATG 
AACCCAGAAG CCGGAAAGCC GTCTGATTTG ATTCTCACAC GACTTTTGGT GCCTCCTTTG 
TGTATCAGAC CCTCCGTTGT GAGTGATTTG AAGTCTGGCA CCAATGAAGA TGATCTGACA 
ATGAAACTGA CAGAAATCAT TTTCCTAAAC GATGTTATTA AAAAGCATCG GATCTCAGGA 
GCCAAGACCC AGATGATCAT GGAGGACTGG GATTTCCTGC AGCTGCAGTG TGCCCTCTAC 
ATTAACAGTG AGCTCTCGGG CATTCCCCTC AACATGGCAC CCAAGAAGTG GACCAGAGGC 
TTCGTCCAAC GCCTGAAGGG AAAACAGGGT CGATTTAGAG GAAATCTCTC AGGAAAGAGA 
GTGGATTTTT CTGGCAGAAC AGTCATCTCG CCCGACCCCA ACCTCCGGAT TGATGAGGTA 
GCTGTGCCAG TTCATGTGGC CAAAATTCTA ACTTTTCCTG AGAAGGTAAA CAAAGCAAAC 
ATCAATTTCT TGAGGAAACT GGTTCAAAAC GGCCCTGAGG TTCACCCAGG AGCAAACTTC 
ATTCAGCAGA GACATACGCA GATGAAAAGG TTTTTGAAAT ACGGAAATCG AGAAAAGATG 
GCTCAAGAGC TCAAGTATGG TGACATCGTA GAGAGACACC TCATCGATGG AGATGTGGTG 
CTGTTCAATC GGCAGCCCTC GCTGCACAAA TTGAGCATTA TGGCTCATCT GGCCAGGGTC 
AAGCCCCACC GGACCTTCAG ATTTAATGAG TGTGTCTGTA CACCCTATAA TGCTGACTTT 
GATGGTGATG AAATGAACCT TCATCTTCCT CAAACAGAAG AAGCTAAAGC AGAGGCCCTT 
GTTCTGATGG GGACTAAAGC AAATCTTGTA ACCCCGAGGA ATGGGGAACC GCTGATTGCT 
GCTATTCAGG ATTTTCTAAC AGGTGCCTAT CTCCTCACTC TCAAGGACAC TTTCTTTGAT 
CGAGCCAAGG CTTGCCAAAT CATTGCTTCA ATACTGGTTG GCAAGGATGA GAAAATTAAA 
GTTCGCCTCC CACCGCCTAC AATCCTAAAG CCTGTCACCC TGTGGACGGG AAAGCAGATC 
TTCAGTGTCA TCCTCAGGCC TAGCGATGAC AATCCAGTGA GGGCCAACCT GCGAACCAAG 
GGCAAGCAGT ACTGTGGCAA AGGGGAAGAT CTCTGTGCCA ATGATTCCTA TGTTACAATC 
CAGAACAGTG AGTTGATGAG TGGCAGCATG GACAAAGGAA CCCTAGGGTC AGGATCCAAG 
AACAATATTT TTTACATTTT GCTGCGAGAC TGGGGACAGA ATGAAGCTGC AGATGCCATG 
TCACGGCTCG CCAGGCTGGC TCCTGTCTAC CTGTCTAACC GTGGTTTCTC AATTGGGATC 
GGTGATGTCA CACCTGGCCA AGGACTGCTG AAGGCCAAGT ATGAGTTGCT GAATGCCGGC 
TACAAGAAAT GTGATGAGTA CATCGAAGCC CTGAACACGG GCAAGCTGCA GCAGCAGCCT 
GGCTGCACTG CTGAGGAGAC CCTGGAGGCA CTGATCCTGA AGGAGCTGTC TGTGATCCGT 
GACCACGCTG GCAGTGCCTG CCTCCGGGAG CTGGACAAGA GCAACAGCCC CCTCACCATG 
GCTCTGTGCG GCTCCAAAGG TTCCTTCATT AACATATCAC AGATGATTGC CTGTGTGGGA 
CAGCAGGCCA TCAGTGGCTC TCGAGTGCCA GACGGCTTTG AAAACAGGTC CTTGCCTCAT 
TTTGAAAAAC ACTCAAAGCT CCCAGCTGCC AAAGGCTTTG TGGCTAATAG CTTTTATTCC 
GGTTTGACAC CAACTGAGTT TTTCTTCCAC ACAATGGCCG GCCGGGAAGG TCTAGTCGAC 
ACGGCTGTAA AGACAGCTGA AACGGGATAC ATGCAGCGAA GGCTTGTCAA ATCTCTTGAA 
GATCTTTGCT CCCAGTATGA TCTGACAGTC CGAAGCTCTA CTGGCGATAT TATCCAGTTC 
ATTTATGGAG GAGATGGCTT AGATCCTGCA GCTATGGAGG GAAAAGATGA ACCTTTGGAG 
TTTAAAAGGG TTCTGGACAA CATCAAAGCA GTCTTCCCGT GTCCCAGTGA GCCTGCTCTC 
AGCAAAAACG AGCTGATCCT GACCACAGAG TCCATCATGA AGAAGAGTGA GTTCCTCTGC 
TGCCAGGACA GCTTCCTGCA GGAAATAAAA AAATTCATTA AGGGGGTCTC TGAGAAGATC 
AAGAAAACCA GAGATAAATA TGGCATCAAT GATAACGGCA CAACAGAGCC CCGTGTGCTG 
TACCAGCTGG ACCGCATCAC CCCCACCCAA GTAGAAAAGT TTCTGGAGAC CTGTAGGGAC 
AAGTACATGA GGGCACAGAT GGAGCCAGGT TCTGCAGTGG GTGCTCTGTG TGCCCAGAGC 
ATTGGTGAGC CAGGCACCCA GATGACCCTG AAGACTTTCC ACTTTGCAGG TGTGGCCTCC 
ATGAACATCA CCCTGGGCGT GCCCCGGATT AAAGAGATCA TCAACGCTTC CAAGGCCATC 
AGCACTCCAA TTATCACAGC ACAGCTAGAC AAGGATGACG ACGCGGATTA TGCTCGCCTC 
GTGAAAGGGA GAATTGAGAA AACCCTCTTG GGAGAGATTT CCGAGTATAT TGAAGAAGTG 
TTTCTTCCTG ATGACTGCTT TATTCTCGTC AAGCTCTCCC TGGAACGGAT TAGGCTTCTG 
AGACTGGAAG TGAACGCTGA GACAGTGAGA TATTCCATCT GCACATCCAA GCTCCGTGTG 
AAGCCCGGTG ATGTGGCTGT TCATGGTGAG GCTGTGGTGT GTGTCACCCC CAGAGAGAAC 
AGCAAGAGCT CCATGTACTA CGTGCTGCAG TTCCTGAAAG AGGATCTCCC CAAGGTGGTG 
GTGCAGGGCA TTCCAGAGGT GTCCAGAGCT GTCATCCACA TTGACGAGCA GAGTGGAAAG 
GAGAAGTACA AGCTTCTGGT GGAAGGTGAT AACCTGCGGG CAGTCATGGC CACACACGGT 
GTGAAGGGCA CCCGAACCAC CTCCAATAAC ACCTATGAGG TGGAGAAAAC TCTGGGCATC 
GAGGCCGCCC GGACAACGAT CATCAATGAA ATCCAGTACA CCATGGTGAA CCACGGCATG 
AGCATCGACA GGAGGCACGT GATGCTGCTC TCCGACCTCA TGACCTACAA GGGTGAAGTC 
CTGGGCATCA CTAGGTTTGG CCTGGCCAAG ATGAAGGAGA GTGTGCTGAT GCTGGCCTCC 
TTTGAGAAGA CGGCTGACCA TCTCTTTGAC GCTGCCTACT TCGGGCAGAA GGACTCTGTG 
TGTGGGGTGT CTGAGTGCAT CATCATGGGA ATCCCAATGA ACATTGGAAC CGGGCTCTTC 
AAGCTGCTTC ACAAGGCTGA CAGGGACCCG AACCCTCCCA AGAGGCCCCT GATCTTCGAC 
ACAAATGAAT TCCACATCCC CCTTGTCACA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Specific combinations of biallelic
Journal of medical genetics55(12)837-846(2018 12)
Paolacci S,Li Y,Agolini E,Bellacchio E,Arboleda-Bustos CE,Carrero D,Bertola D,Al-Gazali L,Alders M,Altmüller J,Arboleda G,Beleggia F,Bruselles A,Ciolfi A,Gillessen-Kaesbach G,Krieg T,Mohammed S,Müller C,Novelli A,Ortega J,Sandoval A,Velasco G,Yigit G,Arboleda H,Lopez-Otin C,Wollnik B,Tartaglia M,Hennekam RC

Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations.
Human genetics137(11-12)921-939(2018 Dec)
Lessel D,Ozel AB,Campbell SE,Saadi A,Arlt MF,McSweeney KM,Plaiasu V,Szakszon K,Szőllős A,Rusu C,Rojas AJ,Lopez-Valdez J,Thiele H,Nürnberg P,Nickerson DA,Bamshad MJ,Li JZ,Kubisch C,Glover TW,Gordon LB

Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome.
American journal of human genetics103(6)968-975(2018 12)
Wambach JA,Wegner DJ,Patni N,Kircher M,Willing MC,Baldridge D,Xing C,Agarwal AK,Vergano SAS,Patel C,Grange DK,Kenney A,Najaf T,Nickerson DA,Bamshad MJ,Cole FS,Garg A

RNA Polymerase III as a Gatekeeper to Prevent Severe VZV Infections.
Trends in molecular medicine24(10)904-915(2018 10)
Carter-Timofte ME,Paludan SR,Mogensen TH

Epigenetic regulation of RNA polymerase III transcription in early breast tumorigenesis.
Oncogene36(49)6793-6804(2017 12)
Park JL,Lee YS,Song MJ,Hong SH,Ahn JH,Seo EH,Shin SP,Lee SJ,Johnson BH,Stampfer MR,Kim HP,Kim SY,Lee YS

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

POLR3A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM