ORF » Species Summary » Homo sapiens » AKR1C4 cDNA ORF clone

AKR1C4 cDNA ORF clone, Homo sapiens(human)

The following AKR1C4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AKR1C4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu24837 NM_001818.4
Latest version!		 Homo sapiens aldo-keto reductase family 1 member C4 (AKR1C4), mRNA. pcDNA3.1-C-(k)DYK or customized vector 5+ $216.30
$309.00
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OHu24837 NM_001818.3 Homo sapiens aldo-keto reductase family 1 member C4 (AKR1C4), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$154.50-$216.30
$309.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    AKR1C4 ( NM_001818.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001809.3 Homo sapiens aldo-keto reductase family 1 member C4 (AKR1C4), mRNA.
    Price & Availability↑
    CloneID OHu24837
    Clone ID Related Accession (Same CDS sequence) NM_001818.4 , NM_001818.3
    Accession Version NM_001818.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 972bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 1506787200000
    Organism Homo sapiens(human)
    Product aldo-keto reductase family 1 member C4
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC020744.1 and D26125.1. This sequence is a reference standard in the RefSeqGene project. On Mar 10, 2011 this sequence version replaced NM_001818.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC020744.1, AK314988.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144835, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGATCCCA AATATCAGCG TGTAGAGCTA AATGATGGTC ACTTCATGCC CGTATTGGGA 
    TTTGGCACCT ATGCACCTCC AGAGGTTCCG AGGAACAGAG CTGTAGAGGT CACCAAATTA 
    GCAATAGAAG CTGGCTTCCG CCATATTGAT TCTGCTTATT TATACAATAA TGAGGAGCAG 
    GTTGGACTGG CCATCCGAAG CAAGATTGCA GATGGCAGTG TGAAGAGAGA AGACATATTC 
    TACACTTCAA AGCTTTGGTG CACTTTCTTT CAACCACAGA TGGTCCAACC AGCCTTGGAA 
    AGCTCACTGA AAAAACTTCA ACTGGACTAT GTTGACCTCT ATCTTCTTCA TTTCCCAATG 
    GCTCTCAAGC CAGGTGAGAC GCCACTACCA AAAGATGAAA ATGGAAAAGT AATATTCGAC 
    ACAGTGGATC TCTCTGCCAC ATGGGAGGTC ATGGAGAAGT GTAAGGATGC AGGATTGGCC 
    AAGTCCATCG GGGTGTCAAA CTTCAACTGC AGGCAGCTGG AGATGATCCT CAACAAGCCA 
    GGACTCAAGT ACAAGCCTGT CTGCAACCAG GTAGAATGTC ATCCTTACCT CAACCAGAGC 
    AAACTGCTGG ATTTCTGCAA GTCAAAAGAC ATTGTTCTGG TTGCCCACAG TGCTCTGGGA 
    ACCCAACGAC ATAAACTATG GGTGGACCCA AACTCCCCAG TTCTTTTGGA GGACCCAGTT 
    CTTTGTGCCT TAGCAAAGAA ACACAAACGA ACCCCAGCCC TGATTGCCCT GCGCTACCAG 
    CTGCAGCGTG GGGTTGTGGT CCTGGCCAAG AGCTACAATG AGCAGCGGAT CAGAGAGAAC 
    ATCCAGGTTT TTGAATTCCA GTTGACATCA GAGGATATGA AAGTTCTAGA TGGTCTAAAC 
    AGAAATTATC GATATGTTGT CATGGATTTT CTTATGGACC ATCCTGATTA TCCATTTTCA 
    GATGAATATT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001809.3
    CDS34..1005
    Translation

    Target ORF information:

    RefSeq Version NM_001818.3
    Organism Homo sapiens(human)
    Definition Homo sapiens aldo-keto reductase family 1 member C4 (AKR1C4), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    		 NM_001818.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGATCCCA AATATCAGCG TGTAGAGCTA AATGATGGTC ACTTCATGCC CGTATTGGGA 
    TTTGGCACCT ATGCACCTCC AGAGGTTCCG AGGAACAGAG CTGTAGAGGT CACCAAATTA 
    GCAATAGAAG CTGGCTTCCG CCATATTGAT TCTGCTTATT TATACAATAA TGAGGAGCAG 
    GTTGGACTGG CCATCCGAAG CAAGATTGCA GATGGCAGTG TGAAGAGAGA AGACATATTC 
    TACACTTCAA AGCTTTGGTG CACTTTCTTT CAACCACAGA TGGTCCAACC AGCCTTGGAA 
    AGCTCACTGA AAAAACTTCA ACTGGACTAT GTTGACCTCT ATCTTCTTCA TTTCCCAATG 
    GCTCTCAAGC CAGGTGAGAC GCCACTACCA AAAGATGAAA ATGGAAAAGT AATATTCGAC 
    ACAGTGGATC TCTCTGCCAC ATGGGAGGTC ATGGAGAAGT GTAAGGATGC AGGATTGGCC 
    AAGTCCATCG GGGTGTCAAA CTTCAACTGC AGGCAGCTGG AGATGATCCT CAACAAGCCA 
    GGACTCAAGT ACAAGCCTGT CTGCAACCAG GTAGAATGTC ATCCTTACCT CAACCAGAGC 
    AAACTGCTGG ATTTCTGCAA GTCAAAAGAC ATTGTTCTGG TTGCCCACAG TGCTCTGGGA 
    ACCCAACGAC ATAAACTATG GGTGGACCCA AACTCCCCAG TTCTTTTGGA GGACCCAGTT 
    CTTTGTGCCT TAGCAAAGAA ACACAAACGA ACCCCAGCCC TGATTGCCCT GCGCTACCAG 
    CTGCAGCGTG GGGTTGTGGT CCTGGCCAAG AGCTACAATG AGCAGCGGAT CAGAGAGAAC 
    ATCCAGGTTT TTGAATTCCA GTTGACATCA GAGGATATGA AAGTTCTAGA TGGTCTAAAC 
    AGAAATTATC GATATGTTGT CATGGATTTT CTTATGGACC ATCCTGATTA TCCATTTTCA 
    GATGAATATT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    AKR1C4 ( NM_001818.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001809.3 Homo sapiens aldo-keto reductase family 1 member C4 (AKR1C4), mRNA.
    Price & Availability↑
    CloneID OHu24837
    Clone ID Related Accession (Same CDS sequence) NM_001818.4 , NM_001818.3
    Accession Version NM_001818.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 972bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 1577808000000
    Organism Homo sapiens(human)
    Product aldo-keto reductase family 1 member C4
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC020744.1, D26125.1 and AL355303.17. On Nov 23, 2018 this sequence version replaced NM_001818.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.108791.1, BC020744.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144835, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGATCCCA AATATCAGCG TGTAGAGCTA AATGATGGTC ACTTCATGCC CGTATTGGGA 
    TTTGGCACCT ATGCACCTCC AGAGGTTCCG AGGAACAGAG CTGTAGAGGT CACCAAATTA 
    GCAATAGAAG CTGGCTTCCG CCATATTGAT TCTGCTTATT TATACAATAA TGAGGAGCAG 
    GTTGGACTGG CCATCCGAAG CAAGATTGCA GATGGCAGTG TGAAGAGAGA AGACATATTC 
    TACACTTCAA AGCTTTGGTG CACTTTCTTT CAACCACAGA TGGTCCAACC AGCCTTGGAA 
    AGCTCACTGA AAAAACTTCA ACTGGACTAT GTTGACCTCT ATCTTCTTCA TTTCCCAATG 
    GCTCTCAAGC CAGGTGAGAC GCCACTACCA AAAGATGAAA ATGGAAAAGT AATATTCGAC 
    ACAGTGGATC TCTCTGCCAC ATGGGAGGTC ATGGAGAAGT GTAAGGATGC AGGATTGGCC 
    AAGTCCATCG GGGTGTCAAA CTTCAACTGC AGGCAGCTGG AGATGATCCT CAACAAGCCA 
    GGACTCAAGT ACAAGCCTGT CTGCAACCAG GTAGAATGTC ATCCTTACCT CAACCAGAGC 
    AAACTGCTGG ATTTCTGCAA GTCAAAAGAC ATTGTTCTGG TTGCCCACAG TGCTCTGGGA 
    ACCCAACGAC ATAAACTATG GGTGGACCCA AACTCCCCAG TTCTTTTGGA GGACCCAGTT 
    CTTTGTGCCT TAGCAAAGAA ACACAAACGA ACCCCAGCCC TGATTGCCCT GCGCTACCAG 
    CTGCAGCGTG GGGTTGTGGT CCTGGCCAAG AGCTACAATG AGCAGCGGAT CAGAGAGAAC 
    ATCCAGGTTT TTGAATTCCA GTTGACATCA GAGGATATGA AAGTTCTAGA TGGTCTAAAC 
    AGAAATTATC GATATGTTGT CATGGATTTT CTTATGGACC ATCCTGATTA TCCATTTTCA 
    GATGAATATT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001809.3
    CDS32..1003
    Translation

    Target ORF information:

    RefSeq Version NM_001818.4
    Organism Homo sapiens(human)
    Definition Homo sapiens aldo-keto reductase family 1 member C4 (AKR1C4), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    		 NM_001818.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGATCCCA AATATCAGCG TGTAGAGCTA AATGATGGTC ACTTCATGCC CGTATTGGGA 
    TTTGGCACCT ATGCACCTCC AGAGGTTCCG AGGAACAGAG CTGTAGAGGT CACCAAATTA 
    GCAATAGAAG CTGGCTTCCG CCATATTGAT TCTGCTTATT TATACAATAA TGAGGAGCAG 
    GTTGGACTGG CCATCCGAAG CAAGATTGCA GATGGCAGTG TGAAGAGAGA AGACATATTC 
    TACACTTCAA AGCTTTGGTG CACTTTCTTT CAACCACAGA TGGTCCAACC AGCCTTGGAA 
    AGCTCACTGA AAAAACTTCA ACTGGACTAT GTTGACCTCT ATCTTCTTCA TTTCCCAATG 
    GCTCTCAAGC CAGGTGAGAC GCCACTACCA AAAGATGAAA ATGGAAAAGT AATATTCGAC 
    ACAGTGGATC TCTCTGCCAC ATGGGAGGTC ATGGAGAAGT GTAAGGATGC AGGATTGGCC 
    AAGTCCATCG GGGTGTCAAA CTTCAACTGC AGGCAGCTGG AGATGATCCT CAACAAGCCA 
    GGACTCAAGT ACAAGCCTGT CTGCAACCAG GTAGAATGTC ATCCTTACCT CAACCAGAGC 
    AAACTGCTGG ATTTCTGCAA GTCAAAAGAC ATTGTTCTGG TTGCCCACAG TGCTCTGGGA 
    ACCCAACGAC ATAAACTATG GGTGGACCCA AACTCCCCAG TTCTTTTGGA GGACCCAGTT 
    CTTTGTGCCT TAGCAAAGAA ACACAAACGA ACCCCAGCCC TGATTGCCCT GCGCTACCAG 
    CTGCAGCGTG GGGTTGTGGT CCTGGCCAAG AGCTACAATG AGCAGCGGAT CAGAGAGAAC 
    ATCCAGGTTT TTGAATTCCA GTTGACATCA GAGGATATGA AAGTTCTAGA TGGTCTAAAC 
    AGAAATTATC GATATGTTGT CATGGATTTT CTTATGGACC ATCCTGATTA TCCATTTTCA 
    GATGAATATT AG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.
    Oncology reports37(4)2025-2032(2017 Apr)
    Shiiba M,Yamagami H,Yamamoto A,Minakawa Y,Okamoto A,Kasamatsu A,Sakamoto Y,Uzawa K,Takiguchi Y,Tanzawa H


    An atlas of genetic influences on human blood metabolites.
    Nature genetics46(6)543-550(2014 Jun)
    Shin SY,Fauman EB,Petersen AK,Krumsiek J,Santos R,Huang J,Arnold M,Erte I,Forgetta V,Yang TP,Walter K,Menni C,Chen L,Vasquez L,Valdes AM,Hyde CL,Wang V,Ziemek D,Roberts P,Xi L,Grundberg E,,Waldenberger M,Richards JB,Mohney RP,Milburn MV,John SL,Trimmer J,Theis FJ,Overington JP,Suhre K,Brosnan MJ,Gieger C,Kastenmüller G,Spector TD,Soranzo N


    Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
    Steroids7949-63(2014 Jan)
    Rižner TL,Penning TM


    Discovery and refinement of loci associated with lipid levels.
    Nature genetics45(11)1274-1283(2013 Nov)
    Willer CJ,Schmidt EM,Sengupta S,Peloso GM,Gustafsson S,Kanoni S,Ganna A,Chen J,Buchkovich ML,Mora S,Beckmann JS,Bragg-Gresham JL,Chang HY,Demirkan A,Den Hertog HM,Do R,Donnelly LA,Ehret GB,Esko T,Feitosa MF,Ferreira T,Fischer K,Fontanillas P,Fraser RM,Freitag DF,Gurdasani D,Heikkilä K,Hyppönen E,Isaacs A,Jackson AU,Johansson Å,Johnson T,Kaakinen M,Kettunen J,Kleber ME,Li X,Luan J,Lyytikäinen LP,Magnusson PKE,Mangino M,Mihailov E,Montasser ME,Müller-Nurasyid M,Nolte IM,O'Connell JR,Palmer CD,Perola M,Petersen AK,Sanna S,Saxena R,Service SK,Shah S,Shungin D,Sidore C,Song C,Strawbridge RJ,Surakka I,Tanaka T,Teslovich TM,Thorleifsson G,Van den Herik EG,Voight BF,Volcik KA,Waite LL,Wong A,Wu Y,Zhang W,Absher D,Asiki G,Barroso I,Been LF,Bolton JL,Bonnycastle LL,Brambilla P,Burnett MS,Cesana G,Dimitriou M,Doney ASF,Döring A,Elliott P,Epstein SE,Ingi Eyjolfsson G,Gigante B,Goodarzi MO,Grallert H,Gravito ML,Groves CJ,Hallmans G,Hartikainen AL,Hayward C,Hernandez D,Hicks AA,Holm H,Hung YJ,Illig T,Jones MR,Kaleebu P,Kastelein JJP,Khaw KT,Kim E,Klopp N,Komulainen P,Kumari M,Langenberg C,Lehtimäki T,Lin SY,Lindström J,Loos RJF,Mach F,McArdle WL,Meisinger C,Mitchell BD,Müller G,Nagaraja R,Narisu N,Nieminen TVM,Nsubuga RN,Olafsson I,Ong KK,Palotie A,Papamarkou T,Pomilla C,Pouta A,Rader DJ,Reilly MP,Ridker PM,Rivadeneira F,Rudan I,Ruokonen A,Samani N,Scharnagl H,Seeley J,Silander K,Stančáková A,Stirrups K,Swift AJ,Tiret L,Uitterlinden AG,van Pelt LJ,Vedantam S,Wainwright N,Wijmenga C,Wild SH,Willemsen G,Wilsgaard T,Wilson JF,Young EH,Zhao JH,Adair LS,Arveiler D,Assimes TL,Bandinelli S,Bennett F,Bochud M,Boehm BO,Boomsma DI,Borecki IB,Bornstein SR,Bovet P,Burnier M,Campbell H,Chakravarti A,Chambers JC,Chen YI,Collins FS,Cooper RS,Danesh J,Dedoussis G,de Faire U,Feranil AB,Ferrières J,Ferrucci L,Freimer NB,Gieger C,Groop LC,Gudnason V,Gyllensten U,Hamsten A,Harris TB,Hingorani A,Hirschhorn JN,Hofman A,Hovingh GK,Hsiung CA,Humphries SE,Hunt SC,Hveem K,Iribarren C,Järvelin MR,Jula A,Kähönen M,Kaprio J,Kesäniemi A,Kivimaki M,Kooner JS,Koudstaal PJ,Krauss RM,Kuh D,Kuusisto J,Kyvik KO,Laakso M,Lakka TA,Lind L,Lindgren CM,Martin NG,März W,McCarthy MI,McKenzie CA,Meneton P,Metspalu A,Moilanen L,Morris AD,Munroe PB,Njølstad I,Pedersen NL,Power C,Pramstaller PP,Price JF,Psaty BM,Quertermous T,Rauramaa R,Saleheen D,Salomaa V,Sanghera DK,Saramies J,Schwarz PEH,Sheu WH,Shuldiner AR,Siegbahn A,Spector TD,Stefansson K,Strachan DP,Tayo BO,Tremoli E,Tuomilehto J,Uusitupa M,van Duijn CM,Vollenweider P,Wallentin L,Wareham NJ,Whitfield JB,Wolffenbuttel BHR,Ordovas JM,Boerwinkle E,Palmer CNA,Thorsteinsdottir U,Chasman DI,Rotter JI,Franks PW,Ripatti S,Cupples LA,Sandhu MS,Rich SS,Boehnke M,Deloukas P,Kathiresan S,Mohlke KL,Ingelsson E,Abecasis GR,


    Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology22(9)632-40(2012 Sep)
    Johansson AG,Nikamo P,Schalling M,Landén M


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