ST6GALNAC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ST6GALNAC2
Entrez Gene ID	10610
Full Name	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Synonyms	SAITL1,SIAT7,SIAT7B,SIATL1,ST6GalNAII,STHM
General protein information	Preferred Names ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Names alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase SIAT7-B ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 ST6 GalNAc alpha-2,6-sialyltransferase 2 ST6GALNAC2, alpha-2,6-sialyltransferase 2 ST6GalNAc II ST6GalNAcII galNAc alpha-2,6-sialyltransferase II sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) B sialyltransferase 7B sialyltransferase-like 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.1
Summary	ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610137

mRNA and Protein(s)

mRNA	Protein	Name
NM_006456.3	NP_006447.2	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 precursor
XM_005256954.4	XP_005257011.1	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 isoform X1
XM_024450539.1	XP_024306307.1	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 isoform X2
NM_006456.2	NP_006447.2	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 precursor
XM_005256954.3	XP_005257011.1	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ST6GALNAC2	NP_006447.2
Xenopus tropicalis (tropical clawed frog)	st6galnac2	NP_989414.2
Canis lupus familiaris (dog)	ST6GALNAC2	NP_001091028.1
Macaca mulatta (Rhesus monkey)	ST6GALNAC2	XP_001105204.1
Mus musculus (house mouse)	St6galnac2	NP_033206.2
Pan troglodytes (chimpanzee)	ST6GALNAC2	NP_001180593.1
Danio rerio (zebrafish)	st6galnac2	NP_001164693.1
Bos taurus (cattle)	ST6GALNAC2	NP_001069001.1
Rattus norvegicus (Norway rat)	St6galnac2	NP_001026822.1
Gallus gallus (chicken)	ST6GALNAC2	NP_990564.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression system for structural and functional studies of human glycosylation enzymes.
Moremen KW, Ramiah A, Stuart M, Steel J, Meng L, Forouhar F, Moniz HA, Gahlay G, Gao Z, Chapla D, Wang S, Yang JY, Prabhakar PK, Johnson R, Rosa MD, Geisler C, Nairn AV, Seetharaman J, Wu SC, Tong L, Gilbert HJ, LaBaer J, Jarvis DL
Nature chemical biology14(2)156-162(2018 02)

Upregulation of microRNA-135b and microRNA-182 promotes chemoresistance of colorectal cancer by targeting ST6GALNAC2 via PI3K/AKT pathway.
Liu B, Liu Y, Zhao L, Pan Y, Shan Y, Li Y, Jia L
Molecular carcinogenesis56(12)2669-2680(2017 Dec)

miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway.
Jia L, Luo S, Ren X, Li Y, Hu J, Liu B, Zhao L, Shan Y, Zhou H
Digestive diseases and sciences62(12)3447-3459(2017 12)

ST6GalNAcII mediates tumor invasion through PI3K/Akt/NF-κB signaling pathway in follicular thyroid carcinoma.
Miao X, Zhao Y
Oncology reports35(4)2131-40(2016 Apr)

Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.
Venkitachalam S, Revoredo L, Varadan V, Fecteau RE, Ravi L, Lutterbaugh J, Markowitz SD, Willis JE, Gerken TA, Guda K
Scientific reports623642(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ST6GALNAC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ST6GALNAC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu104234	XM_024450539.1 Latest version!	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu50036	XM_005256954.4 Latest version!	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu26339	NM_006456.3 Latest version!	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu26339	NM_006456.2	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
OHu50036	XM_005256954.3	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ST6GALNAC2 ( XM_024450539.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306307.1 Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu104234
Clone ID Related Accession (Same CDS sequence)	XM_024450539.1
Accession Version	XM_024450539.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCATTGT GGTTGACAAT GGCACCATTG TTCCTGGAGT CCCCTCAGTG GGGGCCACAG 
GGCTCACACA CCCTGGTCCA GTGGATGCTG AGGGGGTGCC AGGATTCTGG ATGCAAGATA 
CAGCCACTGA AGGACCTGCA GTATATCTTC ATCCCCTCAG ACATCCGCGA CTATGTGATG 
CTGAGATCGG CCATTCTGGG CGTGCCTGTC CCTGAGGGCC TAGATAAAGG GGACAGGCCG 
CACGCCTATT TTGGACCAGA AGCCTCTGCC AGTAAATTCA AGCTGCTACA TCCGGACTTC 
ATCAGCTACC TGACAGAAAG GTTCTTGAAA TCAAAGTTGA TTAACACACA TTTTGGAGAC 
CTATATATGC CTAGTACCGG GGCTCTCATG CTGCTGACAG CTTTGCATAC CTGTGACCAG 
GTCAGTGCCT ATGGATTCAT CACAAGCAAC TACTGGAAAT TTTCCGACCA CTATTTCGAA 
CGAAAAATGA AGCCATTGAT ATTTTATGCA AACCACGATC TGTCCCTGGA AGCTGCCCTG 
TGGAGGGACC TGCACAAGGC CGGCATCCTT CAGCTGTACC AGCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306307.1
CDS	13..600
Translation	MPLWLTMAPLFLESPQWGPQGSHTLVQWMLRGCQDSGCKIQPLKDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR

Target ORF information:

RefSeq Version	XM_024450539.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450539.1

ORF Insert Sequence:

ATGCCATTGT GGTTGACAAT GGCACCATTG TTCCTGGAGT CCCCTCAGTG GGGGCCACAG 
GGCTCACACA CCCTGGTCCA GTGGATGCTG AGGGGGTGCC AGGATTCTGG ATGCAAGATA 
CAGCCACTGA AGGACCTGCA GTATATCTTC ATCCCCTCAG ACATCCGCGA CTATGTGATG 
CTGAGATCGG CCATTCTGGG CGTGCCTGTC CCTGAGGGCC TAGATAAAGG GGACAGGCCG 
CACGCCTATT TTGGACCAGA AGCCTCTGCC AGTAAATTCA AGCTGCTACA TCCGGACTTC 
ATCAGCTACC TGACAGAAAG GTTCTTGAAA TCAAAGTTGA TTAACACACA TTTTGGAGAC 
CTATATATGC CTAGTACCGG GGCTCTCATG CTGCTGACAG CTTTGCATAC CTGTGACCAG 
GTCAGTGCCT ATGGATTCAT CACAAGCAAC TACTGGAAAT TTTCCGACCA CTATTTCGAA 
CGAAAAATGA AGCCATTGAT ATTTTATGCA AACCACGATC TGTCCCTGGA AGCTGCCCTG 
TGGAGGGACC TGCACAAGGC CGGCATCCTT CAGCTGTACC AGCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ST6GALNAC2 ( XM_005256954.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005257011.1 Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu50036
Clone ID Related Accession (Same CDS sequence)	XM_005256954.4 , XM_005256954.3
Accession Version	XM_005256954.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005256954.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGTTCTTG 
AAATCAAAGT TGATTAACAC ACATTTTGGA GACCTATATA TGCCTAGTAC CGGGGCTCTC 
ATGCTGCTGA CAGCTTTGCA TACCTGTGAC CAGGTCAGTG CCTATGGATT CATCACAAGC 
AACTACTGGA AATTTTCCGA CCACTATTTC GAACGAAAAA TGAAGCCATT GATATTTTAT 
GCAAACCACG ATCTGTCCCT GGAAGCTGCC CTGTGGAGGG ACCTGCACAA GGCCGGCATC 
CTTCAGCTGT ACCAGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005257011.1
CDS	259..1299
Translation	MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR

Target ORF information:

RefSeq Version	XM_005256954.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256954.4

ORF Insert Sequence:

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGTTCTTG 
AAATCAAAGT TGATTAACAC ACATTTTGGA GACCTATATA TGCCTAGTAC CGGGGCTCTC 
ATGCTGCTGA CAGCTTTGCA TACCTGTGAC CAGGTCAGTG CCTATGGATT CATCACAAGC 
AACTACTGGA AATTTTCCGA CCACTATTTC GAACGAAAAA TGAAGCCATT GATATTTTAT 
GCAAACCACG ATCTGTCCCT GGAAGCTGCC CTGTGGAGGG ACCTGCACAA GGCCGGCATC 
CTTCAGCTGT ACCAGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ST6GALNAC2 ( XM_005256954.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005257011.1 Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu50036
Clone ID Related Accession (Same CDS sequence)	XM_005256954.4 , XM_005256954.3
Accession Version	XM_005256954.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005256954.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGTTCTTG 
AAATCAAAGT TGATTAACAC ACATTTTGGA GACCTATATA TGCCTAGTAC CGGGGCTCTC 
ATGCTGCTGA CAGCTTTGCA TACCTGTGAC CAGGTCAGTG CCTATGGATT CATCACAAGC 
AACTACTGGA AATTTTCCGA CCACTATTTC GAACGAAAAA TGAAGCCATT GATATTTTAT 
GCAAACCACG ATCTGTCCCT GGAAGCTGCC CTGTGGAGGG ACCTGCACAA GGCCGGCATC 
CTTCAGCTGT ACCAGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005257011.1
CDS	259..1299
Translation	MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR

Target ORF information:

RefSeq Version	XM_005256954.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256954.3

ORF Insert Sequence:

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGTTCTTG 
AAATCAAAGT TGATTAACAC ACATTTTGGA GACCTATATA TGCCTAGTAC CGGGGCTCTC 
ATGCTGCTGA CAGCTTTGCA TACCTGTGAC CAGGTCAGTG CCTATGGATT CATCACAAGC 
AACTACTGGA AATTTTCCGA CCACTATTTC GAACGAAAAA TGAAGCCATT GATATTTTAT 
GCAAACCACG ATCTGTCCCT GGAAGCTGCC CTGTGGAGGG ACCTGCACAA GGCCGGCATC 
CTTCAGCTGT ACCAGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ST6GALNAC2 ( NM_006456.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006447.2 Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), mRNA.

Price & Availability↑

CloneID	OHu26339
Clone ID Related Accession (Same CDS sequence)	NM_006456.3 , NM_006456.2
Accession Version	NM_006456.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC015802.21 and BT019972.1. On May 17, 2019 this sequence version replaced NM_006456.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.255230.1, SRR1660809.201916.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162841 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000225276.10/ ENSP00000225276.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGCCGCAC 
GCCTATTTTG GACCAGAAGC CTCTGCCAGT AAATTCAAGC TGCTACATCC GGACTTCATC 
AGCTACCTGA CAGAAAGGTT CTTGAAATCA AAGTTGATTA ACACACATTT TGGAGACCTA 
TATATGCCTA GTACCGGGGC TCTCATGCTG CTGACAGCTT TGCATACCTG TGACCAGGTC 
AGTGCCTATG GATTCATCAC AAGCAACTAC TGGAAATTTT CCGACCACTA TTTCGAACGA 
AAAATGAAGC CATTGATATT TTATGCAAAC CACGATCTGT CCCTGGAAGC TGCCCTGTGG 
AGGGACCTGC ACAAGGCCGG CATCCTTCAG CTGTACCAGC GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006447.2
CDS	53..1177
Translation	MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR

Target ORF information:

RefSeq Version	NM_006456.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006456.3

ORF Insert Sequence:

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGCCGCAC 
GCCTATTTTG GACCAGAAGC CTCTGCCAGT AAATTCAAGC TGCTACATCC GGACTTCATC 
AGCTACCTGA CAGAAAGGTT CTTGAAATCA AAGTTGATTA ACACACATTT TGGAGACCTA 
TATATGCCTA GTACCGGGGC TCTCATGCTG CTGACAGCTT TGCATACCTG TGACCAGGTC 
AGTGCCTATG GATTCATCAC AAGCAACTAC TGGAAATTTT CCGACCACTA TTTCGAACGA 
AAAATGAAGC CATTGATATT TTATGCAAAC CACGATCTGT CCCTGGAAGC TGCCCTGTGG 
AGGGACCTGC ACAAGGCCGG CATCCTTCAG CTGTACCAGC GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ST6GALNAC2 ( NM_006456.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006447.2 Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), mRNA.

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CloneID	OHu26339
Clone ID Related Accession (Same CDS sequence)	NM_006456.3 , NM_006456.2
Accession Version	NM_006456.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550332800000
Organism	Homo sapiens(human)
Product	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC015802.21 and BT019972.1. On Jun 24, 2008 this sequence version replaced NM_006456.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ251053.1, SRR1660809.201916.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162841 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGCCGCAC 
GCCTATTTTG GACCAGAAGC CTCTGCCAGT AAATTCAAGC TGCTACATCC GGACTTCATC 
AGCTACCTGA CAGAAAGGTT CTTGAAATCA AAGTTGATTA ACACACATTT TGGAGACCTA 
TATATGCCTA GTACCGGGGC TCTCATGCTG CTGACAGCTT TGCATACCTG TGACCAGGTC 
AGTGCCTATG GATTCATCAC AAGCAACTAC TGGAAATTTT CCGACCACTA TTTCGAACGA 
AAAATGAAGC CATTGATATT TTATGCAAAC CACGATCTGT CCCTGGAAGC TGCCCTGTGG 
AGGGACCTGC ACAAGGCCGG CATCCTTCAG CTGTACCAGC GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006447.2
CDS	256..1380
Translation	MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR

Target ORF information:

RefSeq Version	NM_006456.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006456.2

ORF Insert Sequence:

ATGGGGCTCC CGCGCGGGTC GTTCTTCTGG CTGCTGCTCC TGCTCACGGC TGCCTGCTCG 
GGGCTCCTCT TTGCCCTGTA CTTCTCGGCG GTGCAGCGGT ACCCGGGGCC AGCGGCCGGA 
GCCAGGGACA CCACATCATT TGAAGCATTC TTTCAATCCA AGGCATCGAA TTCTTGGACA 
GGAAAGGGCC AGGCCTGCCG ACACCTGCTT CACCTGGCCA TTCAGCGGCA CCCCCACTTC 
CGTGGCCTGT TCAATCTCTC CATTCCAGTG CTGCTGTGGG GGGACCTCTT CACCCCAGCG 
CTCTGGGACC GCCTGAGCCA ACACAAAGCC CCGTATGGCT GGCGGGGGCT CTCTCACCAA 
GTCATCGCCT CCACCCTGAG CCTTCTGAAC GGCTCAGAGA GTGCCAAGCT GTTTGCCCCG 
CCCAGGGACA CCCCTCCAAA GTGTATCCGG TGTGCCGTGG TGGGCAACGG AGGCATTCTG 
AATGGGTCCC GCCAGGGTCC CAACATCGAT GCCCATGACT ATGTATTCAG ACTCAATGGA 
GCTGTGATCA AAGGCTTCGA GCGCGATGTG GGCACCAAGA CTTCCTTCTA TGGTTTCACT 
GTGAACACGA TGAAGAACTC CCTCGTCTCC TACTGGAATC TGGGCTTCAC CTCCGTGCCA 
CAAGGACAGG ACCTGCAGTA TATCTTCATC CCCTCAGACA TCCGCGACTA TGTGATGCTG 
AGATCGGCCA TTCTGGGCGT GCCTGTCCCT GAGGGCCTAG ATAAAGGGGA CAGGCCGCAC 
GCCTATTTTG GACCAGAAGC CTCTGCCAGT AAATTCAAGC TGCTACATCC GGACTTCATC 
AGCTACCTGA CAGAAAGGTT CTTGAAATCA AAGTTGATTA ACACACATTT TGGAGACCTA 
TATATGCCTA GTACCGGGGC TCTCATGCTG CTGACAGCTT TGCATACCTG TGACCAGGTC 
AGTGCCTATG GATTCATCAC AAGCAACTAC TGGAAATTTT CCGACCACTA TTTCGAACGA 
AAAATGAAGC CATTGATATT TTATGCAAAC CACGATCTGT CCCTGGAAGC TGCCCTGTGG 
AGGGACCTGC ACAAGGCCGG CATCCTTCAG CTGTACCAGC GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression system for structural and functional studies of human glycosylation enzymes.
Nature chemical biology14(2)156-162(2018 02)
Moremen KW,Ramiah A,Stuart M,Steel J,Meng L,Forouhar F,Moniz HA,Gahlay G,Gao Z,Chapla D,Wang S,Yang JY,Prabhakar PK,Johnson R,Rosa MD,Geisler C,Nairn AV,Seetharaman J,Wu SC,Tong L,Gilbert HJ,LaBaer J,Jarvis DL

Upregulation of microRNA-135b and microRNA-182 promotes chemoresistance of colorectal cancer by targeting ST6GALNAC2 via PI3K/AKT pathway.
Molecular carcinogenesis56(12)2669-2680(2017 Dec)
Liu B,Liu Y,Zhao L,Pan Y,Shan Y,Li Y,Jia L

miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway.
Digestive diseases and sciences62(12)3447-3459(2017 12)
Jia L,Luo S,Ren X,Li Y,Hu J,Liu B,Zhao L,Shan Y,Zhou H

ST6GalNAcII mediates tumor invasion through PI3K/Akt/NF-κB signaling pathway in follicular thyroid carcinoma.
Oncology reports35(4)2131-40(2016 Apr)
Miao X,Zhao Y

Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.
Scientific reports623642(2016 Mar)
Venkitachalam S,Revoredo L,Varadan V,Fecteau RE,Ravi L,Lutterbaugh J,Markowitz SD,Willis JE,Gerken TA,Guda K

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ST6GALNAC2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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