SERF2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SERF2
Entrez Gene ID	10169
Full Name	small EDRK-rich factor 2
Synonyms	4F5REL,FAM2C,H4F5REL,HsT17089
General protein information	Preferred Names small EDRK-rich factor 2 Names small EDRK-rich factor 2 gastric cancer-related protein VRG107 protein 4F5-related
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q15.3
Disorder MIM:	605054

mRNA and Protein(s)

mRNA	Protein	Name
NM_001199877.1	NP_001186806.1	small EDRK-rich factor 2 isoform c
NM_001199875.1	NP_001186804.1	small EDRK-rich factor 2 isoform a
NM_001199876.1	NP_001186805.1	small EDRK-rich factor 2 isoform b
NM_001199878.2	NP_001186807.1	small EDRK-rich factor 2 isoform d
NM_001018108.4	NP_001018118.1	small EDRK-rich factor 2 isoform c
NM_001199878.1	NP_001186807.1	small EDRK-rich factor 2 isoform d
NM_001199877.2	NP_001186806.1	small EDRK-rich factor 2 isoform c
NM_001018108.3	NP_001018118.1	small EDRK-rich factor 2 isoform c

Pathways from BioSystems

Homologies

Homo sapiens (human)	SERF2	NP_001186806.1
Mus musculus (house mouse)	Serf2	NP_035484.1
Macaca mulatta (Rhesus monkey)	SERF2	XP_001094763.1
Canis lupus familiaris (dog)	SERF2	NP_001239197.1
Bos taurus (cattle)	SERF2	NP_001193277.1
Rattus norvegicus (Norway rat)	Serf2	NP_001092252.1
Pan troglodytes (chimpanzee)	SERF2	NP_001238854.1

Gene Ontology
Bibliography

Related articles in PubMed

Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2.
Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ
Scientific reports8(1)14891(2018 10)

Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
van Ham TJ, Holmberg MA, van der Goot AT, Teuling E, Garcia-Arencibia M, Kim HE, Du D, Thijssen KL, Wiersma M, Burggraaff R, van Bergeijk P, van Rheenen J, Jerre van Veluw G, Hofstra RM, Rubinsztein DC, Nollen EA
Cell142(4)601-12(2010 Aug)

Blocking BE301622 gene expression by RNAi initiates differentiation of neural stem cells in rat.
Wen T, Bao K, Li H
Cell biochemistry and function25(6)775-9(2007 Nov-Dec)

Structured RNAs in the ENCODE selected regions of the human genome.
Washietl S, Pedersen JS, Korbel JO, Stocsits C, Gruber AR, Hackermüller J, Hertel J, Lindemeyer M, Reiche K, Tanzer A, Ucla C, Wyss C, Antonarakis SE, Denoeud F, Lagarde J, Drenkow J, Kapranov P, Gingeras TR, Guigó R, Snyder M, Gerstein MB, Reymond A, Hofacker IL, Stadler PF
Genome research17(6)852-64(2007 Jun)

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y
Molecular cell23(4)607-18(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SERF2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SERF2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07917	NM_001199875.1 Latest version!	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu08153	NM_001199876.1 Latest version!	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu08082	NM_001018108.4 Latest version!	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu08082	NM_001199877.2 Latest version!	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu11587	NM_001199878.2 Latest version!	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu11587	NM_001199878.1	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu08082	NM_001199877.1	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu08082	NM_001018108.3	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SERF2 ( NM_001199875.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186804.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07917
Clone ID Related Accession (Same CDS sequence)	NM_001199875.1
Accession Version	NM_001199875.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 513bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC009869.2, AC018512.6, AK307547.1 and BM970646.1. Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.201619.1, SRR1803614.14367.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGTG 
GGAGTACAGC AGCCAAACGC TGAACTTAGT CCCATCCACT TCCATCTTAT CCTTTGTGCC 
CTTCATCCCC CTGCATCTTG TCCTTTTTGC CCTCTGGTAC CTCCCAGTGC CCCATCATCT 
CTACCCCCAG GGACTCGGAG ATCATGCAGC AGAAGCAGAA AAAGGCAAAC GAGAAGAAGG 
AGGAACCCAA GTAGCTTTGT GGCTTCGTGT CCAACCCTCT TGCCCTTCGC CTGTGTGCCT 
GGAGCCAGTC CCACCACGCT CGCGTTTCCT CCTGTAGTGC TCACAGGTCC CAGCACCGAT 
GGCATTCCCT TTGCCCTGAG TCTGCAGCGG GTCCCTTTTG TGCTTCCTTC CCCTCAGGTA 
GCCTCTCTCC CCCTGGGCCA CTCCCGGGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186804.1
CDS	402..914
Translation	MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRVGVQQPNAELSPIHFHLILCALHPPASCPFCPLVPPSAPSSLPPGTRRSCSRSRKRQTRRRRNPSSFVASCPTLLPFACVPGASPTTLAFPPVVLTGPSTDGIPFALSLQRVPFVLPSPQVASLPLGHSRG

Target ORF information:

RefSeq Version	NM_001199875.1
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199875.1

ORF Insert Sequence:

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGTG 
GGAGTACAGC AGCCAAACGC TGAACTTAGT CCCATCCACT TCCATCTTAT CCTTTGTGCC 
CTTCATCCCC CTGCATCTTG TCCTTTTTGC CCTCTGGTAC CTCCCAGTGC CCCATCATCT 
CTACCCCCAG GGACTCGGAG ATCATGCAGC AGAAGCAGAA AAAGGCAAAC GAGAAGAAGG 
AGGAACCCAA GTAGCTTTGT GGCTTCGTGT CCAACCCTCT TGCCCTTCGC CTGTGTGCCT 
GGAGCCAGTC CCACCACGCT CGCGTTTCCT CCTGTAGTGC TCACAGGTCC CAGCACCGAT 
GGCATTCCCT TTGCCCTGAG TCTGCAGCGG GTCCCTTTTG TGCTTCCTTC CCCTCAGGTA 
GCCTCTCTCC CCCTGGGCCA CTCCCGGGGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERF2 ( NM_001199876.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186805.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08153
Clone ID Related Accession (Same CDS sequence)	NM_001199876.1
Accession Version	NM_001199876.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC009869.2, AC018512.6, BP317864.2 and BM970646.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.107485.1, ERR279827.6588.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGTGCC 
CCATCATCTC TACCCCCAGG GACTCGGAGA TCATGCAGCA GAAGCAGAAA AAGGCAAACG 
AGAAGAAGGA GGAACCCAAG TAGCTTTGTG GCTTCGTGTC CAACCCTCTT GCCCTTCGCC 
TGTGTGCCTG GAGCCAGTCC CACCACGCTC GCGTTTCCTC CTGTAGTGCT CACAGGTCCC 
AGCACCGATG GCATTCCCTT TGCCCTGAGT CTGCAGCGGG TCCCTTTTGT GCTTCCTTCC 
CCTCAGGTAG CCTCTCTCCC CCTGGGCCAC TCCCGGGGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186805.1
CDS	402..803
Translation	MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQSAPSSLPPGTRRSCSRSRKRQTRRRRNPSSFVASCPTLLPFACVPGASPTTLAFPPVVLTGPSTDGIPFALSLQRVPFVLPSPQVASLPLGHSRG

Target ORF information:

RefSeq Version	NM_001199876.1
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199876.1

ORF Insert Sequence:

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGTGCC 
CCATCATCTC TACCCCCAGG GACTCGGAGA TCATGCAGCA GAAGCAGAAA AAGGCAAACG 
AGAAGAAGGA GGAACCCAAG TAGCTTTGTG GCTTCGTGTC CAACCCTCTT GCCCTTCGCC 
TGTGTGCCTG GAGCCAGTCC CACCACGCTC GCGTTTCCTC CTGTAGTGCT CACAGGTCCC 
AGCACCGATG GCATTCCCTT TGCCCTGAGT CTGCAGCGGG TCCCTTTTGT GCTTCCTTCC 
CCTCAGGTAG CCTCTCTCCC CCTGGGCCAC TCCCGGGGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERF2 ( NM_001199877.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186806.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu08082
Clone ID Related Accession (Same CDS sequence)	NM_001199877.1 , NM_001018108.4 , NM_001199877.2 , NM_001018108.3
Accession Version	NM_001199877.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529769600000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ061048.1, BC009869.2, AC018512.6 and BM970646.1. Transcript Variant: This variant (4) differs in the 5' UTR, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (c) has a distinct and shorter C-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.58824.1, BC009869.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186806.1
CDS	934..1113
Translation	MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK

Target ORF information:

RefSeq Version	NM_001199877.1
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199877.1

ORF Insert Sequence:

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERF2 ( NM_001018108.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001018118.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08082
Clone ID Related Accession (Same CDS sequence)	NM_001199877.1 , NM_001018108.4 , NM_001199877.2 , NM_001018108.3
Accession Version	NM_001018108.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008214.1, AC018512.6 and BM970646.1. On Jun 2, 2019 this sequence version replaced NM_001018108.3. Transcript Variant: This variant (3) differs in the 5' UTR, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (c) has a distinct and shorter C-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.105912.1, SRR1803615.193126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018118.1
CDS	58..237
Translation	MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK

Target ORF information:

RefSeq Version	NM_001018108.4
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001018108.4

ORF Insert Sequence:

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERF2 ( NM_001199877.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186806.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu08082
Clone ID Related Accession (Same CDS sequence)	NM_001199877.1 , NM_001018108.4 , NM_001199877.2 , NM_001018108.3
Accession Version	NM_001199877.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018512.6, BQ061048.1, BC009869.2 and BM970646.1. On Jun 2, 2019 this sequence version replaced NM_001199877.1. Transcript Variant: This variant (4) differs in the 5' UTR, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (c) has a distinct and shorter C-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.58824.1, BC009869.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186806.1
CDS	944..1123
Translation	MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK

Target ORF information:

RefSeq Version	NM_001199877.2
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199877.2

ORF Insert Sequence:

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERF2 ( NM_001018108.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001018118.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08082
Clone ID Related Accession (Same CDS sequence)	NM_001199877.1 , NM_001018108.4 , NM_001199877.2 , NM_001018108.3
Accession Version	NM_001018108.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529769600000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008214.1, AC018512.6 and BM970646.1. On Dec 26, 2010 this sequence version replaced NM_001018108.2. Transcript Variant: This variant (3) differs in the 5' UTR, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (c) has a distinct and shorter C-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC008214.1, SRR1803615.193126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018118.1
CDS	536..715
Translation	MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK

Target ORF information:

RefSeq Version	NM_001018108.3
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001018108.3

ORF Insert Sequence:

1
61
121

ATGACCCGCG GTAACCAGCG TGAGCTCGCC CGCCAGAAGA ATATGAAAAA GCAGAGCGAC 
TCGGTTAAGG GAAAGCGCCG AGATGACGGG CTTTCTGCTG CCGCCCGCAA GCAGAGGGAC 
TCGGAGATCA TGCAGCAGAA GCAGAAAAAG GCAAACGAGA AGAAGGAGGA ACCCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERF2 ( NM_001199878.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186807.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu11587
Clone ID Related Accession (Same CDS sequence)	NM_001199878.2 , NM_001199878.1
Accession Version	NM_001199878.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 138bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform d
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018512.6, DA302996.1, BI260545.1 and BM970646.1. On Jun 2, 2019 this sequence version replaced NM_001199878.1. Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, uses a downstream start codon, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (d) is shorter at the N-terminus and has a distinct C-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.49692.1, SRR1803616.1921.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGAAAAAGC AGAGCGACTC GGTTAAGGGA AAGCGCCGAG ATGACGGGCT TTCTGCTGCC 
GCCCGCAAGC AGAGGGACTC GGAGATCATG CAGCAGAAGC AGAAAAAGGC AAACGAGAAG 
AAGGAGGAAC CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186807.1
CDS	328..465
Translation	MKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK

Target ORF information:

RefSeq Version	NM_001199878.2
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199878.2

ORF Insert Sequence:

1
61
121

ATGAAAAAGC AGAGCGACTC GGTTAAGGGA AAGCGCCGAG ATGACGGGCT TTCTGCTGCC 
GCCCGCAAGC AGAGGGACTC GGAGATCATG CAGCAGAAGC AGAAAAAGGC AAACGAGAAG 
AAGGAGGAAC CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SERF2 ( NM_001199878.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186807.1 Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu11587
Clone ID Related Accession (Same CDS sequence)	NM_001199878.2 , NM_001199878.1
Accession Version	NM_001199878.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 138bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529769600000
Organism	Homo sapiens(human)
Product	small EDRK-rich factor 2 isoform d
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA302996.1, BI260545.1, AC018512.6 and BM970646.1. Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, uses a downstream start codon, and uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (d) is shorter at the N-terminus and has a distinct C-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DA302996.1, SRR1803614.49692.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGAAAAAGC AGAGCGACTC GGTTAAGGGA AAGCGCCGAG ATGACGGGCT TTCTGCTGCC 
GCCCGCAAGC AGAGGGACTC GGAGATCATG CAGCAGAAGC AGAAAAAGGC AAACGAGAAG 
AAGGAGGAAC CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186807.1
CDS	271..408
Translation	MKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK

Target ORF information:

RefSeq Version	NM_001199878.1
Organism	Homo sapiens(human)
Definition	Homo sapiens small EDRK-rich factor 2 (SERF2), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199878.1

ORF Insert Sequence:

1
61
121

ATGAAAAAGC AGAGCGACTC GGTTAAGGGA AAGCGCCGAG ATGACGGGCT TTCTGCTGCC 
GCCCGCAAGC AGAGGGACTC GGAGATCATG CAGCAGAAGC AGAAAAAGGC AAACGAGAAG 
AAGGAGGAAC CCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2.
Scientific reports8(1)14891(2018 10)
Balasubramaniam M,Ayyadevara S,Shmookler Reis RJ

Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
Cell142(4)601-12(2010 Aug)
van Ham TJ,Holmberg MA,van der Goot AT,Teuling E,Garcia-Arencibia M,Kim HE,Du D,Thijssen KL,Wiersma M,Burggraaff R,van Bergeijk P,van Rheenen J,Jerre van Veluw G,Hofstra RM,Rubinsztein DC,Nollen EA

Blocking BE301622 gene expression by RNAi initiates differentiation of neural stem cells in rat.
Cell biochemistry and function25(6)775-9(2007 Nov-Dec)
Wen T,Bao K,Li H

Structured RNAs in the ENCODE selected regions of the human genome.
Genome research17(6)852-64(2007 Jun)
Washietl S,Pedersen JS,Korbel JO,Stocsits C,Gruber AR,Hackermüller J,Hertel J,Lindemeyer M,Reiche K,Tanzer A,Ucla C,Wyss C,Antonarakis SE,Denoeud F,Lagarde J,Drenkow J,Kapranov P,Gingeras TR,Guigó R,Snyder M,Gerstein MB,Reymond A,Hofacker IL,Stadler PF

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Molecular cell23(4)607-18(2006 Aug)
Kim SC,Sprung R,Chen Y,Xu Y,Ball H,Pei J,Cheng T,Kho Y,Xiao H,Xiao L,Grishin NV,White M,Yang XJ,Zhao Y

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SERF2 cDNA ORF clone, Homo sapiens(human)

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