CTDSP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CTDSP2
Entrez Gene ID	10106
Full Name	CTD small phosphatase 2
Synonyms	OS4,PSR2,SCP2
General protein information	Preferred Names CTD small phosphatase 2 Names carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 NLI-interacting factor 2 conserved gene amplified in osteosarcoma nuclear LIM interactor-interacting factor 2 protein OS-4 small C-terminal domain phosphatase 2 small CTD phosphatase 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q14.1
Disorder MIM:	608711

mRNA and Protein(s)

mRNA	Protein	Name
NM_005730.3	NP_005721.3	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
NM_005730.4	NP_005721.3	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
XM_005268556.1	XP_005268613.1	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 isoform X1
XM_005268556.2	XP_005268613.1	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CTDSP2	NP_005721.3
Mus musculus (house mouse)	Ctdsp2	NP_001106941.1
Xenopus tropicalis (tropical clawed frog)	ctdsp2	NP_001006793.1
Pan troglodytes (chimpanzee)	CTDSP2	XP_001167131.1
Macaca mulatta (Rhesus monkey)	CTDSP2	XP_001116527.1
Eremothecium gossypii	AGOS_AAL158W	NP_982384.1
Canis lupus familiaris (dog)	CTDSP2	XP_538256.2
Danio rerio (zebrafish)	ctdsp2	NP_955838.1
Saccharomyces cerevisiae (baker's yeast)	PSR1	NP_013091.1
Kluyveromyces lactis	KLLA0F15620g	XP_455782.1
Saccharomyces cerevisiae (baker's yeast)	PSR2	NP_013119.1
Bos taurus (cattle)	CTDSP2	NP_001039400.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).
Kloet DE, Polderman PE, Eijkelenboom A, Smits LM, van Triest MH, van den Berg MC, Groot Koerkamp MJ, van Leenen D, Lijnzaad P, Holstege FC, Burgering BM
The Biochemical journal469(2)289-98(2015 Jul)

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.
Simonis N, Rual JF, Lemmens I, Boxus M, Hirozane-Kishikawa T, Gatot JS, Dricot A, Hao T, Vertommen D, Legros S, Daakour S, Klitgord N, Martin M, Willaert JF, Dequiedt F, Navratil V, Cusick ME, Burny A, Van Lint C, Hill DE, Tavernier J, Kettmann R, Vidal M, Twizere JC
Retrovirology926(2012 Mar)

Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.
Sapkota G, Knockaert M, Alarcón C, Montalvo E, Brivanlou AH, Massagué J
The Journal of biological chemistry281(52)40412-9(2006 Dec)

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.
Knockaert M, Sapkota G, Alarcón C, Massagué J, Brivanlou AH
Proceedings of the National Academy of Sciences of the United States of America103(32)11940-5(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CTDSP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CTDSP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu46241	XM_005268556.2 Latest version!	Homo sapiens CTD small phosphatase 2 (CTDSP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu05097	NM_005730.4 Latest version!	Homo sapiens CTD small phosphatase 2 (CTDSP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu05097	NM_005730.3	Homo sapiens CTD small phosphatase 2 (CTDSP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
OHu46241	XM_005268556.1	Homo sapiens CTD small phosphatase 2 (CTDSP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CTDSP2 ( XM_005268556.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268613.1 Homo sapiens CTD small phosphatase 2 (CTDSP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46241
Clone ID Related Accession (Same CDS sequence)	XM_005268556.1 , XM_005268556.2
Accession Version	XM_005268556.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGGTACGTGA CTCTGGCCTG ATCCCAGGGA CCTGCCTGCT CCCAGAGGTG 
ACAGAGGAAG ATCAAGGAAG GATCTGTGTG GTCATTGACC TCGATGAAAC CCTTGTGCAT 
AGCTCCTTTA AGCCAATCAA CAATGCTGAC TTCATAGTGC CTATAGAGAT TGAGGGGACC 
ACTCACCAGG TGTATGTGCT CAAGAGGCCT TATGTGGATG AGTTCCTGAG ACGCATGGGG 
GAACTCTTTG AATGTGTTCT CTTCACTGCC AGCCTGGCCA AGTATGCCGA CCCTGTGACA 
GACCTGCTGG ACCGGTGTGG GGTGTTCCGG GCCCGCCTAT TCCGTGAGTC TTGCGTGTTC 
CACCAGGGCT GCTACGTCAA GGACCTCAGC CGCCTGGGGA GGGACCTGAG AAAGACCCTC 
ATCCTGGACA ACTCGCCTGC TTCTTACATA TTCCACCCCG AGAATGCAGT GCCTGTGCAG 
TCCTGGTTTG ATGACATGGC AGACACTGAG TTGCTGAACC TGATCCCAAT CTTTGAGGAG 
CTGAGCGGAG CAGAGGACGT CTACACCAGC CTTGGGCAGC TGCGGGCCCC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268613.1
CDS	290..1123
Translation	MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQVRDSGLIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP

Target ORF information:

RefSeq Version	XM_005268556.1
Organism	Homo sapiens(human)
Definition	Homo sapiens CTD small phosphatase 2 (CTDSP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268556.1

ORF Insert Sequence:

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGGTACGTGA CTCTGGCCTG ATCCCAGGGA CCTGCCTGCT CCCAGAGGTG 
ACAGAGGAAG ATCAAGGAAG GATCTGTGTG GTCATTGACC TCGATGAAAC CCTTGTGCAT 
AGCTCCTTTA AGCCAATCAA CAATGCTGAC TTCATAGTGC CTATAGAGAT TGAGGGGACC 
ACTCACCAGG TGTATGTGCT CAAGAGGCCT TATGTGGATG AGTTCCTGAG ACGCATGGGG 
GAACTCTTTG AATGTGTTCT CTTCACTGCC AGCCTGGCCA AGTATGCCGA CCCTGTGACA 
GACCTGCTGG ACCGGTGTGG GGTGTTCCGG GCCCGCCTAT TCCGTGAGTC TTGCGTGTTC 
CACCAGGGCT GCTACGTCAA GGACCTCAGC CGCCTGGGGA GGGACCTGAG AAAGACCCTC 
ATCCTGGACA ACTCGCCTGC TTCTTACATA TTCCACCCCG AGAATGCAGT GCCTGTGCAG 
TCCTGGTTTG ATGACATGGC AGACACTGAG TTGCTGAACC TGATCCCAAT CTTTGAGGAG 
CTGAGCGGAG CAGAGGACGT CTACACCAGC CTTGGGCAGC TGCGGGCCCC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTDSP2 ( XM_005268556.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268613.1 Homo sapiens CTD small phosphatase 2 (CTDSP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46241
Clone ID Related Accession (Same CDS sequence)	XM_005268556.1 , XM_005268556.2
Accession Version	XM_005268556.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005268556.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGGTACGTGA CTCTGGCCTG ATCCCAGGGA CCTGCCTGCT CCCAGAGGTG 
ACAGAGGAAG ATCAAGGAAG GATCTGTGTG GTCATTGACC TCGATGAAAC CCTTGTGCAT 
AGCTCCTTTA AGCCAATCAA CAATGCTGAC TTCATAGTGC CTATAGAGAT TGAGGGGACC 
ACTCACCAGG TGTATGTGCT CAAGAGGCCT TATGTGGATG AGTTCCTGAG ACGCATGGGG 
GAACTCTTTG AATGTGTTCT CTTCACTGCC AGCCTGGCCA AGTATGCCGA CCCTGTGACA 
GACCTGCTGG ACCGGTGTGG GGTGTTCCGG GCCCGCCTAT TCCGTGAGTC TTGCGTGTTC 
CACCAGGGCT GCTACGTCAA GGACCTCAGC CGCCTGGGGA GGGACCTGAG AAAGACCCTC 
ATCCTGGACA ACTCGCCTGC TTCTTACATA TTCCACCCCG AGAATGCAGT GCCTGTGCAG 
TCCTGGTTTG ATGACATGGC AGACACTGAG TTGCTGAACC TGATCCCAAT CTTTGAGGAG 
CTGAGCGGAG CAGAGGACGT CTACACCAGC CTTGGGCAGC TGCGGGCCCC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268613.1
CDS	290..1123
Translation	MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQVRDSGLIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP

Target ORF information:

RefSeq Version	XM_005268556.2
Organism	Homo sapiens(human)
Definition	Homo sapiens CTD small phosphatase 2 (CTDSP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268556.2

ORF Insert Sequence:

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGGTACGTGA CTCTGGCCTG ATCCCAGGGA CCTGCCTGCT CCCAGAGGTG 
ACAGAGGAAG ATCAAGGAAG GATCTGTGTG GTCATTGACC TCGATGAAAC CCTTGTGCAT 
AGCTCCTTTA AGCCAATCAA CAATGCTGAC TTCATAGTGC CTATAGAGAT TGAGGGGACC 
ACTCACCAGG TGTATGTGCT CAAGAGGCCT TATGTGGATG AGTTCCTGAG ACGCATGGGG 
GAACTCTTTG AATGTGTTCT CTTCACTGCC AGCCTGGCCA AGTATGCCGA CCCTGTGACA 
GACCTGCTGG ACCGGTGTGG GGTGTTCCGG GCCCGCCTAT TCCGTGAGTC TTGCGTGTTC 
CACCAGGGCT GCTACGTCAA GGACCTCAGC CGCCTGGGGA GGGACCTGAG AAAGACCCTC 
ATCCTGGACA ACTCGCCTGC TTCTTACATA TTCCACCCCG AGAATGCAGT GCCTGTGCAG 
TCCTGGTTTG ATGACATGGC AGACACTGAG TTGCTGAACC TGATCCCAAT CTTTGAGGAG 
CTGAGCGGAG CAGAGGACGT CTACACCAGC CTTGGGCAGC TGCGGGCCCC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTDSP2 ( NM_005730.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005721.3 Homo sapiens CTD small phosphatase 2 (CTDSP2), mRNA.

Price & Availability↑

CloneID	OHu05097
Clone ID Related Accession (Same CDS sequence)	NM_005730.3 , NM_005730.4
Accession Version	NM_005730.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB001093.1, CN313995.1, BC018922.2 and AC121759.9. On Apr 20, 2006 this sequence version replaced NM_005730.2. ##Evidence-Data-START## Transcript exon combination :: AF000152.1, AK226076.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGATCCCAGG GACCTGCCTG CTCCCAGAGG TGACAGAGGA AGATCAAGGA 
AGGATCTGTG TGGTCATTGA CCTCGATGAA ACCCTTGTGC ATAGCTCCTT TAAGCCAATC 
AACAATGCTG ACTTCATAGT GCCTATAGAG ATTGAGGGGA CCACTCACCA GGTGTATGTG 
CTCAAGAGGC CTTATGTGGA TGAGTTCCTG AGACGCATGG GGGAACTCTT TGAATGTGTT 
CTCTTCACTG CCAGCCTGGC CAAGTATGCC GACCCTGTGA CAGACCTGCT GGACCGGTGT 
GGGGTGTTCC GGGCCCGCCT ATTCCGTGAG TCTTGCGTGT TCCACCAGGG CTGCTACGTC 
AAGGACCTCA GCCGCCTGGG GAGGGACCTG AGAAAGACCC TCATCCTGGA CAACTCGCCT 
GCTTCTTACA TATTCCACCC CGAGAATGCA GTGCCTGTGC AGTCCTGGTT TGATGACATG 
GCAGACACTG AGTTGCTGAA CCTGATCCCA ATCTTTGAGG AGCTGAGCGG AGCAGAGGAC 
GTCTACACCA GCCTTGGGCA GCTGCGGGCC CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005721.3
CDS	530..1345
Translation	MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP

Target ORF information:

RefSeq Version	NM_005730.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CTD small phosphatase 2 (CTDSP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005730.3

ORF Insert Sequence:

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGATCCCAGG GACCTGCCTG CTCCCAGAGG TGACAGAGGA AGATCAAGGA 
AGGATCTGTG TGGTCATTGA CCTCGATGAA ACCCTTGTGC ATAGCTCCTT TAAGCCAATC 
AACAATGCTG ACTTCATAGT GCCTATAGAG ATTGAGGGGA CCACTCACCA GGTGTATGTG 
CTCAAGAGGC CTTATGTGGA TGAGTTCCTG AGACGCATGG GGGAACTCTT TGAATGTGTT 
CTCTTCACTG CCAGCCTGGC CAAGTATGCC GACCCTGTGA CAGACCTGCT GGACCGGTGT 
GGGGTGTTCC GGGCCCGCCT ATTCCGTGAG TCTTGCGTGT TCCACCAGGG CTGCTACGTC 
AAGGACCTCA GCCGCCTGGG GAGGGACCTG AGAAAGACCC TCATCCTGGA CAACTCGCCT 
GCTTCTTACA TATTCCACCC CGAGAATGCA GTGCCTGTGC AGTCCTGGTT TGATGACATG 
GCAGACACTG AGTTGCTGAA CCTGATCCCA ATCTTTGAGG AGCTGAGCGG AGCAGAGGAC 
GTCTACACCA GCCTTGGGCA GCTGCGGGCC CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTDSP2 ( NM_005730.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005721.3 Homo sapiens CTD small phosphatase 2 (CTDSP2), mRNA.

Price & Availability↑

CloneID	OHu05097
Clone ID Related Accession (Same CDS sequence)	NM_005730.3 , NM_005730.4
Accession Version	NM_005730.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN313995.1, BC018922.2 and AC121759.9. On Nov 22, 2018 this sequence version replaced NM_005730.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF000152.1, AK226076.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000398073.7/ ENSP00000381148.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGATCCCAGG GACCTGCCTG CTCCCAGAGG TGACAGAGGA AGATCAAGGA 
AGGATCTGTG TGGTCATTGA CCTCGATGAA ACCCTTGTGC ATAGCTCCTT TAAGCCAATC 
AACAATGCTG ACTTCATAGT GCCTATAGAG ATTGAGGGGA CCACTCACCA GGTGTATGTG 
CTCAAGAGGC CTTATGTGGA TGAGTTCCTG AGACGCATGG GGGAACTCTT TGAATGTGTT 
CTCTTCACTG CCAGCCTGGC CAAGTATGCC GACCCTGTGA CAGACCTGCT GGACCGGTGT 
GGGGTGTTCC GGGCCCGCCT ATTCCGTGAG TCTTGCGTGT TCCACCAGGG CTGCTACGTC 
AAGGACCTCA GCCGCCTGGG GAGGGACCTG AGAAAGACCC TCATCCTGGA CAACTCGCCT 
GCTTCTTACA TATTCCACCC CGAGAATGCA GTGCCTGTGC AGTCCTGGTT TGATGACATG 
GCAGACACTG AGTTGCTGAA CCTGATCCCA ATCTTTGAGG AGCTGAGCGG AGCAGAGGAC 
GTCTACACCA GCCTTGGGCA GCTGCGGGCC CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005721.3
CDS	295..1110
Translation	MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP

Target ORF information:

RefSeq Version	NM_005730.4
Organism	Homo sapiens(human)
Definition	Homo sapiens CTD small phosphatase 2 (CTDSP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005730.4

ORF Insert Sequence:

ATGGAACACG GCTCCATCAT CACCCAGGCG CGGAGGGAAG ACGCCCTGGT GCTCACCAAG 
CAAGGCCTGG TCTCCAAGTC CTCTCCTAAG AAGCCTCGTG GACGTAACAT CTTCAAGGCC 
CTTTTCTGCT GTTTTCGCGC CCAGCATGTT GGCCAGTCAA GTTCCTCCAC TGAGCTCGCT 
GCGTATAAGG AGGAAGCAAA CACCATTGCT AAGTCGGATC TGCTCCAGTG TCTCCAGTAC 
CAGTTCTACC AGATCCCAGG GACCTGCCTG CTCCCAGAGG TGACAGAGGA AGATCAAGGA 
AGGATCTGTG TGGTCATTGA CCTCGATGAA ACCCTTGTGC ATAGCTCCTT TAAGCCAATC 
AACAATGCTG ACTTCATAGT GCCTATAGAG ATTGAGGGGA CCACTCACCA GGTGTATGTG 
CTCAAGAGGC CTTATGTGGA TGAGTTCCTG AGACGCATGG GGGAACTCTT TGAATGTGTT 
CTCTTCACTG CCAGCCTGGC CAAGTATGCC GACCCTGTGA CAGACCTGCT GGACCGGTGT 
GGGGTGTTCC GGGCCCGCCT ATTCCGTGAG TCTTGCGTGT TCCACCAGGG CTGCTACGTC 
AAGGACCTCA GCCGCCTGGG GAGGGACCTG AGAAAGACCC TCATCCTGGA CAACTCGCCT 
GCTTCTTACA TATTCCACCC CGAGAATGCA GTGCCTGTGC AGTCCTGGTT TGATGACATG 
GCAGACACTG AGTTGCTGAA CCTGATCCCA ATCTTTGAGG AGCTGAGCGG AGCAGAGGAC 
GTCTACACCA GCCTTGGGCA GCTGCGGGCC CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).
The Biochemical journal469(2)289-98(2015 Jul)
Kloet DE,Polderman PE,Eijkelenboom A,Smits LM,van Triest MH,van den Berg MC,Groot Koerkamp MJ,van Leenen D,Lijnzaad P,Holstege FC,Burgering BM

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.
Retrovirology926(2012 Mar)
Simonis N,Rual JF,Lemmens I,Boxus M,Hirozane-Kishikawa T,Gatot JS,Dricot A,Hao T,Vertommen D,Legros S,Daakour S,Klitgord N,Martin M,Willaert JF,Dequiedt F,Navratil V,Cusick ME,Burny A,Van Lint C,Hill DE,Tavernier J,Kettmann R,Vidal M,Twizere JC

Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.
The Journal of biological chemistry281(52)40412-9(2006 Dec)
Sapkota G,Knockaert M,Alarcón C,Montalvo E,Brivanlou AH,Massagué J

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.
Proceedings of the National Academy of Sciences of the United States of America103(32)11940-5(2006 Aug)
Knockaert M,Sapkota G,Alarcón C,Massagué J,Brivanlou AH

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

CTDSP2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM