| Gene Symbol | TMEM170B |
| Entrez Gene ID | 100113407 |
| Full Name | transmembrane protein 170B |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome |
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TMEM170B cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following TMEM170B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM170B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu01882 Clone ID Related Accession (Same CDS sequence) NM_001100829.2 , NM_001100829.3 Accession Version NM_001100829.2 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 399bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1506873600000 Organism Homo sapiens(human) Product transmembrane protein 170B Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB092520.1, AL357518.15 and BE670213.1. On Jan 16, 2013 this sequence version replaced NM_001100829.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.80081.1, SRR1803615.488209.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361ATGAAGGCGG AGGGGGGCGA CCACTCCATG ATCAACCTGT CGGTGCAGCA GGTCCTGAGC
CTCTGGGCCC ACGGGACGGT GCTGAGGAAC CTCACGGAGA TGTGGTACTG GATCTTCCTC
TGGGCTCTCT TCTCTTCTCT GTTTGTCCAT GGTGCTGCAG GAGTGTTGAT GTTTGTGATG
CTGCAGAGGC ATAGGCAGGG AAGAGTCATC TCTGTCATTG CAGTCAGCAT TGGATTTCTG
GCTTCTGTAA CTGGAGCGAT GATTACCAGT GCAGCAGTAG CGGGCATTTA CAGAGTAGCT
GGGAAGAACA TGGCCCCTTT GGAAGCGCTG GTATGGGGCG TTGGACAGAC TGTACTGACA
TTAATCATCT CCTTTTCAAG GATCCTCGCT ACACTTTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001094299.1 CDS 52..450 Translation 
Target ORF information:
RefSeq Version NM_001100829.2 Organism Homo sapiens(human) Definition Homo sapiens transmembrane protein 170B (TMEM170B), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001100829.2
ORF Insert Sequence:
1
61
121
181
241
301
361ATGAAGGCGG AGGGGGGCGA CCACTCCATG ATCAACCTGT CGGTGCAGCA GGTCCTGAGC
CTCTGGGCCC ACGGGACGGT GCTGAGGAAC CTCACGGAGA TGTGGTACTG GATCTTCCTC
TGGGCTCTCT TCTCTTCTCT GTTTGTCCAT GGTGCTGCAG GAGTGTTGAT GTTTGTGATG
CTGCAGAGGC ATAGGCAGGG AAGAGTCATC TCTGTCATTG CAGTCAGCAT TGGATTTCTG
GCTTCTGTAA CTGGAGCGAT GATTACCAGT GCAGCAGTAG CGGGCATTTA CAGAGTAGCT
GGGAAGAACA TGGCCCCTTT GGAAGCGCTG GTATGGGGCG TTGGACAGAC TGTACTGACA
TTAATCATCT CCTTTTCAAG GATCCTCGCT ACACTTTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu01882 Clone ID Related Accession (Same CDS sequence) NM_001100829.2 , NM_001100829.3 Accession Version NM_001100829.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 399bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1560528000000 Organism Homo sapiens(human) Product transmembrane protein 170B Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL357518.15, DB092520.1 and BE670213.1. On Nov 22, 2018 this sequence version replaced NM_001100829.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.80081.1, SRR1803615.488209.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379426.2/ ENSP00000368737.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.
1
61
121
181
241
301
361ATGAAGGCGG AGGGGGGCGA CCACTCCATG ATCAACCTGT CGGTGCAGCA GGTCCTGAGC
CTCTGGGCCC ACGGGACGGT GCTGAGGAAC CTCACGGAGA TGTGGTACTG GATCTTCCTC
TGGGCTCTCT TCTCTTCTCT GTTTGTCCAT GGTGCTGCAG GAGTGTTGAT GTTTGTGATG
CTGCAGAGGC ATAGGCAGGG AAGAGTCATC TCTGTCATTG CAGTCAGCAT TGGATTTCTG
GCTTCTGTAA CTGGAGCGAT GATTACCAGT GCAGCAGTAG CGGGCATTTA CAGAGTAGCT
GGGAAGAACA TGGCCCCTTT GGAAGCGCTG GTATGGGGCG TTGGACAGAC TGTACTGACA
TTAATCATCT CCTTTTCAAG GATCCTCGCT ACACTTTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001094299.1 CDS 530..928 Translation
Target ORF information:
RefSeq Version NM_001100829.3 Organism Homo sapiens(human) Definition Homo sapiens transmembrane protein 170B (TMEM170B), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_001100829.3
ORF Insert Sequence:
1
61
121
181
241
301
361ATGAAGGCGG AGGGGGGCGA CCACTCCATG ATCAACCTGT CGGTGCAGCA GGTCCTGAGC
CTCTGGGCCC ACGGGACGGT GCTGAGGAAC CTCACGGAGA TGTGGTACTG GATCTTCCTC
TGGGCTCTCT TCTCTTCTCT GTTTGTCCAT GGTGCTGCAG GAGTGTTGAT GTTTGTGATG
CTGCAGAGGC ATAGGCAGGG AAGAGTCATC TCTGTCATTG CAGTCAGCAT TGGATTTCTG
GCTTCTGTAA CTGGAGCGAT GATTACCAGT GCAGCAGTAG CGGGCATTTA CAGAGTAGCT
GGGAAGAACA TGGCCCCTTT GGAAGCGCTG GTATGGGGCG TTGGACAGAC TGTACTGACA
TTAATCATCT CCTTTTCAAG GATCCTCGCT ACACTTTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Transmembrane protein 170B is a novel breast tumorigenesis suppressor gene that inhibits the Wnt/β-catenin pathway.
Cell death & disease9(2)91(2018 01)
Li M,Han Y,Zhou H,Li X,Lin C,Zhang E,Chi X,Hu J,Xu H
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Genome research16(1)55-65(2006 Jan)
Kimura K,Wakamatsu A,Suzuki Y,Ota T,Nishikawa T,Yamashita R,Yamamoto J,Sekine M,Tsuritani K,Wakaguri H,Ishii S,Sugiyama T,Saito K,Isono Y,Irie R,Kushida N,Yoneyama T,Otsuka R,Kanda K,Yokoi T,Kondo H,Wagatsuma M,Murakawa K,Ishida S,Ishibashi T,Takahashi-Fujii A,Tanase T,Nagai K,Kikuchi H,Nakai K,Isogai T,Sugano S
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