ACTN2 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACTN2
Entrez Gene ID	396263
Full Name	actinin alpha 2
General protein information	Preferred Names actinin alpha 2 Names alpha-actinin-2 F-actin cross-linking protein alpha-actinin skeletal muscle
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205323.1	NP_990654.1	alpha-actinin-2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ACTN2	XP_001158729.2
Macaca mulatta (Rhesus monkey)	ACTN2	XP_001097795.1
Rattus norvegicus (Norway rat)	Actn2	NP_001163796.1
Gallus gallus (chicken)	ACTN2	NP_990654.1
Danio rerio (zebrafish)	actn2	NP_001032662.1
Xenopus tropicalis (tropical clawed frog)	actn2	NP_001005053.1
Homo sapiens (human)	ACTN2	NP_001094.1
Canis lupus familiaris (dog)	ACTN2	XP_856116.1
Bos taurus (cattle)	ACTN2	NP_001029807.1
Mus musculus (house mouse)	Actn2	NP_150371.4

Gene Ontology
Bibliography

Related articles in PubMed

Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells.
Guvakova MA, Adams JC, Boettiger D
Journal of cell science115(Pt 21)4149-65(2002 Nov)

A chick skeletal-muscle alpha-actinin gene gives rise to two alternatively spliced isoforms which differ in the EF-hand Ca(2+)-binding domain.
Parr T, Waites GT, Patel B, Millake DB, Critchley DR
European journal of biochemistry210(3)801-9(1992 Dec)

An interaction between zyxin and alpha-actinin.
Crawford AW, Michelsen JW, Beckerle MC
The Journal of cell biology116(6)1381-93(1992 Mar)

Transfection of chicken skeletal muscle alpha-actinin cDNA into nonmuscle and myogenic cells: dimerization is not essential for alpha-actinin to bind to microfilaments.
Tokuue Y, Goto S, Imamura M, Obinata T, Masaki T, Endo T
Experimental cell research197(2)158-67(1991 Dec)

Primary structure of chicken skeletal muscle and fibroblast alpha-actinins deduced from cDNA sequences.
Arimura C, Suzuki T, Yanagisawa M, Imamura M, Hamada Y, Masaki T
European journal of biochemistry177(3)649-55(1988 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ACTN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACTN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26985	NM_205323.1 Latest version!	Gallus gallus actinin alpha 2 (ACTN2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACTN2 ( NM_205323.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990654.1 Gallus gallus actinin alpha 2 (ACTN2), mRNA.

Price & Availability↑

CloneID	OGa26985
Clone ID Related Accession (Same CDS sequence)	NM_205323.1
Accession Version	NM_205323.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2694bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Gallus gallus(chicken)
Product	alpha-actinin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X59247.1. ##Evidence-Data-START## Transcript exon combination :: X59247.1 [ECO:0000332] ##Evidence-Data-END##

ATGAACAGCA TGAACCAGAT AGAAACAAAC ATGCAGTACA CCTACAACTA TGAAGAAGAT 
GAGTACATGA CCCAAGAGGA AGAATGGGAC AGGGACCTGC TTCTGGACCC AGCATGGGAG 
AAACAGCAAA GGAAGACGTT TACAGCTTGG TGCAATTCCC ACCTCAGGAA AGCAGGCACA 
CAGATTGAGA ACATTGAGGA GGACTTCAGA AATGGTCTCA AACTGATGCT GCTCTTGGAA 
GTTATTTCAG GGGAAAGACT ACCGAAACCA GACAGAGGGA AAATGCGCTT CCATAAAATT 
GCTAATGTCA ACAAAGCTCT GGATTATATT GCCAGCAAAG GAGTGAAACT TGTGTCCATT 
GGTGCAGAAG AAATTGTTGA TGGCAATGTG AAAATGACAC TGGGTATGAT CTGGACCATC 
ATCCTTCGCT TTGCTATTCA AGATATTTCA GTGGAAGAGA CCTCTGCCAA AGAAGGGCTG 
CTGCTGTGGT GTCAAAGAAA AACTGCTCCT TACAGAAATG TGAACATTCA GAACTTCCAT 
CTTAGCTGGA AAGATGGCCT TGGATTATGT GCACTTATCC ACAGACACCG ACCTGACCTT 
ATTGACTACT CCAAGCTAAA TAAGGATGAC CCCATAGGAA ATATCAACCT TGCCATGGAA 
ATTGCTGAGA AACATCTGGA TATCCCTAAG ATGTTGGATG CAGAAGATAT TGTGAACACT 
CCCAAACCTG ATGAGAGAGC TATCATGACA TATGTGTCCT GCTTCTACCA TGCTTTTGCT 
GGAGCAGAGC AGGCTGAGAC TGCAGCAAAC CGGATCTGTA AGGTGCTTGC TGTGAATCAA 
GAAAATGAGA GGTTGATGGA AGAGTATGAG AGACTTGCAA GTGAGCTTTT AGAATGGATT 
CGCAGGACAA TTCCTTGGCT GGAAAACAGG ACCCCGGAAA AAACAATGCA GGCCATGCAG 
AAGAAATTAG AGGATTTCCG GGACTACCGC CGCAAACACA AACCTCCCAA AGTTCAAGAG 
AAATGTCAGC TGGAGATCAA TTTCAACACC CTGCAGACAA AACTGAGAAT CAGCAATCGA 
CCAGCTTTCA TGCCATCGGA GGGAAAAATG GTTTCAGATA TTGCTGGCGC TTGGCAGAGG 
CTTGAACAAG CTGAGAAAGG CTATGAAGAG TGGCTGCTGA ATGAAATACG AAGACTGGAA 
AGACTTGAAC ACTTGGCTGA GAAATTTAGA CAGAAGGCTT CCACTCATGA GCAGTGGGCA 
TATGGCAAAG AGCAGATCTT ACTTCAGAAG GATTATGAAT CTGCATCTCT GACAGAAGTC 
CGTGCCATGT TGAGGAAACA TGAGGCTTTT GAGAGCGATT TGGCTGCTCA CCAGGACAGG 
GTGGAACAGA TCGCTGCCAT TGCCCAGGAG CTGAATGAAC TGGACTATCA CGATGCTGCA 
AGTGTCAATG ATCGATGCCA AAAGATATGT GACCAATGGG ACAGCTTGGG AACACTTACT 
CAGAAAAGGA GAGAGGCACT GGAGAGGACA GAGAAATTGC TTGAAACAAT TGATCAGCTT 
CACCTGGAGT TTGCCAAAAG AGCTGCTCCT TTCAACAACT GGATGGAAGG TGCTATGGAA 
GACCTACAGG ACATGTTTAT TGTTCATAGC ATAGAGGAAA TTCAGAGTTT AATCTCTGCA 
CATGATCAAT TTAAAGCTAC TTTGCCAGAG GCAGATGGTG AAAGACAGGC CATACTGTCA 
ATCCAGAATG AAGTTGAAAA AGTTATTCAG AGTTACAGCA TGAGAATAAG TGCAAGCAAT 
CCTTACAGCA CTGTTACTGT GGAAGAGATT CGCACCAAGT GGGAAAAGGT GAAGCAGCTG 
GTACCTCAGA GGGATCAATC ATTGCAGGAA GAACTAGCCC GCCAGCATGC CAATGAACGC 
CTGCGTCGCC AGTTTGCTGC TCAGGCCAAT GTCATTGGGC CATGGATCCA GACCAAGATG 
GAAGAAATTG CCCGCAGCTC TATTGAAATG ACAGGGCCTT TGGAGGACCA GATGAATCAG 
CTGAAGCAAT ATGAGCAAAA TATCATTAAC TATAAACACA ACATTGATAA ACTGGAAGGA 
GATCATCAGC TCATACAAGA AGCCTTGGTG TTTGACAACA AACACACCAA CTATACTATG 
GAGCATATCC GTGTTGGATG GGAGCTCCTA CTTACTACCA TTGCTCGAAC TATCAATGAG 
GTTGAGACTC AGATCCTCAC AAGAGATGCC AAGGGTATCA CCCAGGAGCA AATGAATGAC 
TTCAGAGCAT CATTCAATCA TTTTGACAGG AGGAAGAACG GACTGATGGA CCATGATGAT 
TTCAGAGCTT GCTTGATTTC AATGGGTTAT GATTTGGGTG AAGCTGAGTT TGCTAGAATC 
ATGTCCTTGG TTGACCCCAA TGGACAAGGA ACCGTCACTT TCCAGTCCTT CATTGACTTC 
ATGACCAGAG AAACAGCAGA TACGGACACG GCTGAGCAAG TGATAGCTTC CTTCAGAATC 
CTGGCTTCAG ATAAGCCTTA TATCCTGGCA GATGAGTTAC GTCGAGAGCT GCCTCCTGAG 
CAGGCTCAGT ACTGCATCAA GAGAATGCCA CAATACACGG GCCCAGGTTC TGTTCCTGGA 
GCCCTGGATT ACACCTCTTT TTCATCAGCA CTGTATGGAG AGAGCGATCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990654.1
CDS	274..2967
Translation	MNSMNQIETNMQYTYNYEEDEYMTQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHLSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHEQWAYGKEQILLQKDYESASLTEVRAMLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNDRCQKICDQWDSLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLISAHDQFKATLPEADGERQAILSIQNEVEKVIQSYSMRISASNPYSTVTVEEIRTKWEKVKQLVPQRDQSLQEELARQHANERLRRQFAAQANVIGPWIQTKMEEIARSSIEMTGPLEDQMNQLKQYEQNIINYKHNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNDFRASFNHFDRRKNGLMDHDDFRACLISMGYDLGEAEFARIMSLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILADELRRELPPEQAQYCIKRMPQYTGPGSVPGALDYTSFSSALYGESDL

Target ORF information:

RefSeq Version	NM_205323.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus actinin alpha 2 (ACTN2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205323.1

ORF Insert Sequence:

ATGAACAGCA TGAACCAGAT AGAAACAAAC ATGCAGTACA CCTACAACTA TGAAGAAGAT 
GAGTACATGA CCCAAGAGGA AGAATGGGAC AGGGACCTGC TTCTGGACCC AGCATGGGAG 
AAACAGCAAA GGAAGACGTT TACAGCTTGG TGCAATTCCC ACCTCAGGAA AGCAGGCACA 
CAGATTGAGA ACATTGAGGA GGACTTCAGA AATGGTCTCA AACTGATGCT GCTCTTGGAA 
GTTATTTCAG GGGAAAGACT ACCGAAACCA GACAGAGGGA AAATGCGCTT CCATAAAATT 
GCTAATGTCA ACAAAGCTCT GGATTATATT GCCAGCAAAG GAGTGAAACT TGTGTCCATT 
GGTGCAGAAG AAATTGTTGA TGGCAATGTG AAAATGACAC TGGGTATGAT CTGGACCATC 
ATCCTTCGCT TTGCTATTCA AGATATTTCA GTGGAAGAGA CCTCTGCCAA AGAAGGGCTG 
CTGCTGTGGT GTCAAAGAAA AACTGCTCCT TACAGAAATG TGAACATTCA GAACTTCCAT 
CTTAGCTGGA AAGATGGCCT TGGATTATGT GCACTTATCC ACAGACACCG ACCTGACCTT 
ATTGACTACT CCAAGCTAAA TAAGGATGAC CCCATAGGAA ATATCAACCT TGCCATGGAA 
ATTGCTGAGA AACATCTGGA TATCCCTAAG ATGTTGGATG CAGAAGATAT TGTGAACACT 
CCCAAACCTG ATGAGAGAGC TATCATGACA TATGTGTCCT GCTTCTACCA TGCTTTTGCT 
GGAGCAGAGC AGGCTGAGAC TGCAGCAAAC CGGATCTGTA AGGTGCTTGC TGTGAATCAA 
GAAAATGAGA GGTTGATGGA AGAGTATGAG AGACTTGCAA GTGAGCTTTT AGAATGGATT 
CGCAGGACAA TTCCTTGGCT GGAAAACAGG ACCCCGGAAA AAACAATGCA GGCCATGCAG 
AAGAAATTAG AGGATTTCCG GGACTACCGC CGCAAACACA AACCTCCCAA AGTTCAAGAG 
AAATGTCAGC TGGAGATCAA TTTCAACACC CTGCAGACAA AACTGAGAAT CAGCAATCGA 
CCAGCTTTCA TGCCATCGGA GGGAAAAATG GTTTCAGATA TTGCTGGCGC TTGGCAGAGG 
CTTGAACAAG CTGAGAAAGG CTATGAAGAG TGGCTGCTGA ATGAAATACG AAGACTGGAA 
AGACTTGAAC ACTTGGCTGA GAAATTTAGA CAGAAGGCTT CCACTCATGA GCAGTGGGCA 
TATGGCAAAG AGCAGATCTT ACTTCAGAAG GATTATGAAT CTGCATCTCT GACAGAAGTC 
CGTGCCATGT TGAGGAAACA TGAGGCTTTT GAGAGCGATT TGGCTGCTCA CCAGGACAGG 
GTGGAACAGA TCGCTGCCAT TGCCCAGGAG CTGAATGAAC TGGACTATCA CGATGCTGCA 
AGTGTCAATG ATCGATGCCA AAAGATATGT GACCAATGGG ACAGCTTGGG AACACTTACT 
CAGAAAAGGA GAGAGGCACT GGAGAGGACA GAGAAATTGC TTGAAACAAT TGATCAGCTT 
CACCTGGAGT TTGCCAAAAG AGCTGCTCCT TTCAACAACT GGATGGAAGG TGCTATGGAA 
GACCTACAGG ACATGTTTAT TGTTCATAGC ATAGAGGAAA TTCAGAGTTT AATCTCTGCA 
CATGATCAAT TTAAAGCTAC TTTGCCAGAG GCAGATGGTG AAAGACAGGC CATACTGTCA 
ATCCAGAATG AAGTTGAAAA AGTTATTCAG AGTTACAGCA TGAGAATAAG TGCAAGCAAT 
CCTTACAGCA CTGTTACTGT GGAAGAGATT CGCACCAAGT GGGAAAAGGT GAAGCAGCTG 
GTACCTCAGA GGGATCAATC ATTGCAGGAA GAACTAGCCC GCCAGCATGC CAATGAACGC 
CTGCGTCGCC AGTTTGCTGC TCAGGCCAAT GTCATTGGGC CATGGATCCA GACCAAGATG 
GAAGAAATTG CCCGCAGCTC TATTGAAATG ACAGGGCCTT TGGAGGACCA GATGAATCAG 
CTGAAGCAAT ATGAGCAAAA TATCATTAAC TATAAACACA ACATTGATAA ACTGGAAGGA 
GATCATCAGC TCATACAAGA AGCCTTGGTG TTTGACAACA AACACACCAA CTATACTATG 
GAGCATATCC GTGTTGGATG GGAGCTCCTA CTTACTACCA TTGCTCGAAC TATCAATGAG 
GTTGAGACTC AGATCCTCAC AAGAGATGCC AAGGGTATCA CCCAGGAGCA AATGAATGAC 
TTCAGAGCAT CATTCAATCA TTTTGACAGG AGGAAGAACG GACTGATGGA CCATGATGAT 
TTCAGAGCTT GCTTGATTTC AATGGGTTAT GATTTGGGTG AAGCTGAGTT TGCTAGAATC 
ATGTCCTTGG TTGACCCCAA TGGACAAGGA ACCGTCACTT TCCAGTCCTT CATTGACTTC 
ATGACCAGAG AAACAGCAGA TACGGACACG GCTGAGCAAG TGATAGCTTC CTTCAGAATC 
CTGGCTTCAG ATAAGCCTTA TATCCTGGCA GATGAGTTAC GTCGAGAGCT GCCTCCTGAG 
CAGGCTCAGT ACTGCATCAA GAGAATGCCA CAATACACGG GCCCAGGTTC TGTTCCTGGA 
GCCCTGGATT ACACCTCTTT TTCATCAGCA CTGTATGGAG AGAGCGATCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells.
Journal of cell science115(Pt 21)4149-65(2002 Nov)
Guvakova MA,Adams JC,Boettiger D

A chick skeletal-muscle alpha-actinin gene gives rise to two alternatively spliced isoforms which differ in the EF-hand Ca(2+)-binding domain.
European journal of biochemistry210(3)801-9(1992 Dec)
Parr T,Waites GT,Patel B,Millake DB,Critchley DR

An interaction between zyxin and alpha-actinin.
The Journal of cell biology116(6)1381-93(1992 Mar)
Crawford AW,Michelsen JW,Beckerle MC

Transfection of chicken skeletal muscle alpha-actinin cDNA into nonmuscle and myogenic cells: dimerization is not essential for alpha-actinin to bind to microfilaments.
Experimental cell research197(2)158-67(1991 Dec)
Tokuue Y,Goto S,Imamura M,Obinata T,Masaki T,Endo T

Primary structure of chicken skeletal muscle and fibroblast alpha-actinins deduced from cDNA sequences.
European journal of biochemistry177(3)649-55(1988 Nov)
Arimura C,Suzuki T,Yanagisawa M,Imamura M,Hamada Y,Masaki T

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

ACTN2 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM