| Gene Symbol | GREM1 |
| Entrez Gene ID | 395826 |
| Full Name | gremlin 1, DAN family BMP antagonist |
| Synonyms | Drm |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Gallus gallus(chicken) |
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GREM1 cDNA ORF clone, Gallus gallus(chicken)
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Gene
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Clones
gRNAs
The following GREM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GREM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OGa28274 Clone ID Related Accession (Same CDS sequence) NM_204978.2 Accession Version NM_204978.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 555bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577203200000 Organism Gallus gallus(chicken) Product gremlin-1 precursor Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF045799.1. On Aug 30, 2012 this sequence version replaced NM_204978.1. ##Evidence-Data-START## Transcript exon combination :: AF045799.1, CR733243.1 [ECO:0000332] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541ATGGTCCGCA CACTGTATGC CATCGGCGCT GTGTTTCTTC TGACGGGATT TCTGCTACCG
ACAGCAGAAG GGAGAAAGAG GAATCGTGGA TCTCAAGGCG CTATCCCTCC TCCTGACAAG
GATCAGCCCA ATGATTCAGA GCAGATGCAG ACACAGCAGC AGTCAGGCTC CAGGCATCGA
GAAAGAGGAA AAGGCACCTC AATGCCTGCT GAGGAGGTGC TGGAGTCCAG CCAGGAGGCA
CTGCACATCA CTGAGCGCAA ATACCTAAAA CGGGATTGGT GCAAAACTCA GCCCCTCAAA
CAAACTATCC ATGAAGAAGG CTGCAACAGT CGCACCATTA TCAACAGGTT CTGCTATGGC
CAATGCAATT CTTTCTACAT CCCCAGGCAT GTCCGCAAAG AGGAAGGCTC TTTCCAGTCT
TGTTCCTTCT GCAAGCCCAA GAAATTTACC ACCATGACTG TTACCCTCAA CTGCCCTGAG
CTTCAGCCCC CTAGGAAGAA GAAAAGAATC ACCCGCGTGA AGGAGTGTCG GTGTATATCT
ATCGACTTGG ACTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_990309.1 CDS 80..634 Translation 
Target ORF information:
RefSeq Version NM_204978.2 Organism Gallus gallus(chicken) Definition Gallus gallus gremlin 1, DAN family BMP antagonist (GREM1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_204978.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541ATGGTCCGCA CACTGTATGC CATCGGCGCT GTGTTTCTTC TGACGGGATT TCTGCTACCG
ACAGCAGAAG GGAGAAAGAG GAATCGTGGA TCTCAAGGCG CTATCCCTCC TCCTGACAAG
GATCAGCCCA ATGATTCAGA GCAGATGCAG ACACAGCAGC AGTCAGGCTC CAGGCATCGA
GAAAGAGGAA AAGGCACCTC AATGCCTGCT GAGGAGGTGC TGGAGTCCAG CCAGGAGGCA
CTGCACATCA CTGAGCGCAA ATACCTAAAA CGGGATTGGT GCAAAACTCA GCCCCTCAAA
CAAACTATCC ATGAAGAAGG CTGCAACAGT CGCACCATTA TCAACAGGTT CTGCTATGGC
CAATGCAATT CTTTCTACAT CCCCAGGCAT GTCCGCAAAG AGGAAGGCTC TTTCCAGTCT
TGTTCCTTCT GCAAGCCCAA GAAATTTACC ACCATGACTG TTACCCTCAA CTGCCCTGAG
CTTCAGCCCC CTAGGAAGAA GAAAAGAATC ACCCGCGTGA AGGAGTGTCG GTGTATATCT
ATCGACTTGG ACTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OGa150774 Clone ID Related Accession (Same CDS sequence) XM_025150591.1 Accession Version XM_025150591.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 555bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1526400000000 Organism Gallus gallus(chicken) Product gremlin-1 isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006092.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
61
121
181
241
301
361
421
481
541ATGGTCCGCA CACTGTATGC CATCGGCGCT GTGTTTCTTC TGACGGGATT TCTGCTACCG
ACAGCAGAAG GGAGAAAGAG GAATCGTGGA TCTCAAGGCG CTATCCCTCC TCCTGACAAG
GATCAGCCCA ATGATTCAGA GCAGATGCAG ACACAGCAGC AGTCAGGCTC CAGGCATCGA
GAAAGAGGAA AAGGCACCTC AATGCCTGCT GAGGAGGTGC TGGAGTCCAG CCAGGAGGCA
CTGCACATCA CTGAGCGCAA ATACCTAAAA CGGGATTGGT GCAAAACTCA GCCCCTCAAA
CAAACTATCC ATGAAGAAGG CTGCAACAGT CGCACCATTA TCAACAGGTT CTGCTACGGC
CAATGCAATT CTTTCTACAT CCCCAGGCAT GTCCGCAAAG AGGAAGGCTC TTTCCAGTCT
TGTTCCTTCT GCAAGCCCAA GAAATTTACC ACCATGACTG TTACCCTCAA CTGCCCTGAG
CTTCAGCCCC CTAGGAAGAA GAAAAGAATC ACCCGCGTGA AGGAGTGTCG GTGTATATCT
ATCGACTTGG ACTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_025006359.1 CDS 596..1150 Translation
Target ORF information:
RefSeq Version XM_025150591.1 Organism Gallus gallus(chicken) Definition Gallus gallus gremlin 1, DAN family BMP antagonist (GREM1), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_025150591.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541ATGGTCCGCA CACTGTATGC CATCGGCGCT GTGTTTCTTC TGACGGGATT TCTGCTACCG
ACAGCAGAAG GGAGAAAGAG GAATCGTGGA TCTCAAGGCG CTATCCCTCC TCCTGACAAG
GATCAGCCCA ATGATTCAGA GCAGATGCAG ACACAGCAGC AGTCAGGCTC CAGGCATCGA
GAAAGAGGAA AAGGCACCTC AATGCCTGCT GAGGAGGTGC TGGAGTCCAG CCAGGAGGCA
CTGCACATCA CTGAGCGCAA ATACCTAAAA CGGGATTGGT GCAAAACTCA GCCCCTCAAA
CAAACTATCC ATGAAGAAGG CTGCAACAGT CGCACCATTA TCAACAGGTT CTGCTACGGC
CAATGCAATT CTTTCTACAT CCCCAGGCAT GTCCGCAAAG AGGAAGGCTC TTTCCAGTCT
TGTTCCTTCT GCAAGCCCAA GAAATTTACC ACCATGACTG TTACCCTCAA CTGCCCTGAG
CTTCAGCCCC CTAGGAAGAA GAAAAGAATC ACCCGCGTGA AGGAGTGTCG GTGTATATCT
ATCGACTTGG ACTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Autopodial development is selectively impaired by misexpression of chordin-like 1 in the chick limb.
Developmental biology381(1)159-69(2013 Sep)
Allen JM,McGlinn E,Hill A,Warman ML
Twist2 contributes to termination of limb bud outgrowth and patterning through direct regulation of Grem1.
Developmental biology370(1)145-53(2012 Oct)
Wade C,Brinas I,Welfare M,Wicking C,Farlie PG
Tgfbeta2 and 3 are coexpressed with their extracellular regulator Ltbp1 in the early limb bud and modulate mesodermal outgrowth and BMP signaling in chicken embryos.
BMC developmental biology1069(2010 Jun)
Lorda-Diez CI,Montero JA,Garcia-Porrero JA,Hurle JM
Regulation of Gremlin expression in the posterior limb bud.
Developmental biology299(1)12-21(2006 Nov)
Nissim S,Hasso SM,Fallon JF,Tabin CJ
Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype.
Nature431(7011)946-57(2004 Oct)
Jaillon O,Aury JM,Brunet F,Petit JL,Stange-Thomann N,Mauceli E,Bouneau L,Fischer C,Ozouf-Costaz C,Bernot A,Nicaud S,Jaffe D,Fisher S,Lutfalla G,Dossat C,Segurens B,Dasilva C,Salanoubat M,Levy M,Boudet N,Castellano S,Anthouard V,Jubin C,Castelli V,Katinka M,Vacherie B,Biémont C,Skalli Z,Cattolico L,Poulain J,De Berardinis V,Cruaud C,Duprat S,Brottier P,Coutanceau JP,Gouzy J,Parra G,Lardier G,Chapple C,McKernan KJ,McEwan P,Bosak S,Kellis M,Volff JN,Guigó R,Zody MC,Mesirov J,Lindblad-Toh K,Birren B,Nusbaum C,Kahn D,Robinson-Rechavi M,Laudet V,Schachter V,Quétier F,Saurin W,Scarpelli C,Wincker P,Lander ES,Weissenbach J,Roest Crollius H
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