sox6 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	sox6
Entrez Gene ID	567154
Full Name	SRY (sex determining region Y)-box 6
Synonyms	fc35a10,fc50e03,sox-lz,sox6b,wu:fc35a10,wu:fc50e03
General protein information	Preferred Names SRY (sex determining region Y)-box 6 Names transcription factor SOX-6 SRY-box containing gene 6
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001123009.1	NP_001116481.1	transcription factor SOX-6

Pathways from BioSystems

Homologies

Homo sapiens (human)	SOX6	NP_001139291.1
Rattus norvegicus (Norway rat)	Sox6	NP_001019922.1
Pan troglodytes (chimpanzee)	SOX6	XP_003312980.1
Danio rerio (zebrafish)	sox6	NP_001116481.1
Bos taurus (cattle)	SOX6	NP_001178347.1
Xenopus tropicalis (tropical clawed frog)	sox6	NP_001116887.1
Canis lupus familiaris (dog)	SOX6	XP_005633754.1
Mus musculus (house mouse)	Sox6	NP_001264255.1
Gallus gallus (chicken)	SOX6	XP_004941454.1

Gene Ontology
Bibliography

Related articles in PubMed

Copy Number Variation in SOX6 Contributes to Chicken Muscle Development.
Lin S, Lin X, Zhang Z, Jiang M, Rao Y, Nie Q, Zhang X
Genes9(1)(2018 Jan)

A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development.
Ciarlo C, Kaufman CK, Kinikoglu B, Michael J, Yang S, D Amato C, Blokzijl-Franke S, den Hertog J, Schlaeger TM, Zhou Y, Liao E, Zon LI
eLife6(2017 08)

Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle.
Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G
Cell reports17(9)2354-2366(2016 11)

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis.
Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, Stünkel W
Development (Cambridge, England)143(6)950-61(2016 Mar)

Cartilage development requires the function of Estrogen-related receptor alpha that directly regulates sox9 expression in zebrafish.
Kim YI, No Lee J, Bhandari S, Nam IK, Yoo KW, Kim SJ, Oh GS, Kim HJ, So HS, Choe SK, Park R
Scientific reports518011(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following sox6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sox6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02128	NM_001123009.1 Latest version!	Danio rerio SRY-box transcription factor 6 (sox6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sox6 ( NM_001123009.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001116481.1 Danio rerio SRY-box transcription factor 6 (sox6), mRNA.

Price & Availability↑

CloneID	ODa02128
Clone ID Related Accession (Same CDS sequence)	NM_001123009.1
Accession Version	NM_001123009.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1561824000000
Organism	Danio rerio(zebrafish)
Product	transcription factor SOX-6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EU532205.1. On Apr 6, 2008 this sequence version replaced XM_690446.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: EU532205.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA3505370 [ECO:0000348] ##Evidence-Data-END##

ATGTCTTCCA AGCAAGCCAC CTCTCCATTT ACCTCGACCC CTGATGGAGG TGAGGATGGA 
GTGAATCAGG AGCGTATGCC CTGGGAGAAG GAGGAGAACT CAGAGTCGCT AGTTGCCCCT 
CAGCTGCCCC TGCACAATCT GCTCCACAAC AAACCTCCCC TGGAGGAGCT CCAGCCAATC 
AGCAGCAGCG TGCCACCCGA ATCCGACTGG GACAGCCTGA TGTCAGCCCA GCAGCGCATG 
GAATCGGACA GCAATAAAGT ATGTTCCTTA TACTCCTTCC GGAATAACTC TACCTCTCCA 
CACAAGCCAG AGGAGGGGGC CAGGGAGCGT GGCGACCTGC TGAGCAGCTC AGCCTTCGGT 
ACGCCAGAAC GCCGCAAAGG AAGCCTGGCC GATGTGGTGG ACACACTGAA ACAGAAGAAA 
CTGGAGGAGA TGACAAAGAC AGAACAAGAC GAATCCTCCT GTATGGAGAA ACTCCTTTCT 
AAAGACTGGA AAGAGAAGAT GGAGCGACTG AACACTGGCG AGCTGTTAGG AGAAATTAAA 
GGTACTCCAG AAAGTCTTGC AGAGAAGGAG CGACAACTCT CCACCATGAT TACACAGCTC 
ATCAGTCTAC GAGAGCAGCT TCTGGCAGCC CATGATGAGC AGAAGAAACT GGCCGCCTCT 
CAGATGGAGA AACAGCGTCA GCAAATGGAG CTGGCACGCC AACAGCAAGA GCAGATCGCC 
AGACAACAGC AGCAACTTCT GCAGCAACAG CACAAAATCA ATCTCCTCCA GCAGCAGATT 
CAGGTCCAGG GTCACATGCC TCCGCTCATG ATCCCCATTT TTCCACACGA CCAGCGCACT 
CTGGCAGCAG CCGCAGCAGC TCAGCAGGGC TTCCTCTTCC CCCCAGGCAT GTCCTATAAG 
CCAGGTGATA ACTACCCGGT GCAGTTCATT CCATCCACAA TGGCAGCTGC TGCCGCGTCA 
GGACTCAACC CTCTCCAGCT CCAGCAACTC TACGCCGCCC AGCTGGCCAG CATGCAGGTC 
TCTCCAGGAG CCAAGATGCC TCCGCTGCCC CAGCCCCCCA ATTCTGCTGG GCAGATCTCC 
CCGTCTGGCT TGAAGAACGA GAAGAGGTCC TCAACCCCCC TGGCTCAAGT CAAGGAGGAG 
GGAACGCAGC CTCTCAACCT CTCCGCCCGG CCTAAAACAG CTGAGCCCAT CAAATCCCCC 
ACATCCCCGA CACAGAGCCT CTTCCCAGGC AGCAAGAGCA GCCCCAACAG CCTCTCCAAG 
AGCGGAGACA TACCCAGTCC CATCGGAGGA TTGGGCCGCG GCTCGTCTCT GGACATCCTG 
TCCAGCCTGA ACTCGACGGC GCTGTTTGGA GATCAGGACG CAGTGATGAA GGCCATCCAA 
GAGGCGAGGA AGATGAGAGA GCAGATTCAG AGAGAGCAGC TTCAGCATCA TCAGCAGGGA 
ATGGAGGTCA AGCTGTCTGC CCTCACCAGC ATGGGCTTGA ACAACTGCAG GACAGAGAAG 
GAGAGGTCTC ATTATGACAA TCTGGGTCAT CACTTGAGCA AACTTGGTGA AGATGGAAAG 
ATTGGTCATA GAGTCATTGA CCTCACCAGG CCAGAAGACT TTGAGGGAGG CGCCAGCACT 
ACCGAGGCAC GGGTCTACAG GGAACCCCGG GGAAGGAACA GCAACGAACC TCACATCAAA 
CGGCCCATGA ACGCCTTCAT GGTCTGGGCC AAAGATGAGC GCCGCAAAAT CCTTCAGGCC 
TTCCCAGACA TGCACAACTC CAACATCAGC AAAATCTTGG GATCTCGCTG GAAGTCTATG 
ACGAACCAGG AGAAACAACC GTATTACGAA GAGCAGGCAC GGCTCAGCAA GATCCACCTG 
GAGAAATACC CCAACTACAA GTACAAACCC AGACCCAAGC GCACCTGCAT CATCGACGGC 
AAGAAGTTGC GCATCAGCGA GTACAAGCAG ATGATGAGGT CACGGAGACA AGAGATGAGG 
CAGTTCTTCA CTGTGGGGCA GCAGCCACAG ACGCAGATCC CCATCACCAC CAGCGCAGGC 
GTTGTGTACC CGGGTGCCAT AACCATGGCC ACCACAACGC CATCCCCGCA CATGACGTCA 
GACTGCTCCA GTGCCTCGGC CAGCCCTGAA CCCACCATCC CCGTCATCCA GAGCACCTTC 
AACATGAAGA TGGAACCGGG TACCATGGTG CCCAGCGACG CAGTGAACGG AGAGGACGAG 
ATGGACATGT ACGAGGACTT TGAGGACGAG CCCAAATCGG ACTACAGCAG TGAGAATGAC 
ACACATGAGC CGGTCAGTGC CAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116481.1
CDS	35..2341
Translation	MSSKQATSPFTSTPDGGEDGVNQERMPWEKEENSESLVAPQLPLHNLLHNKPPLEELQPISSSVPPESDWDSLMSAQQRMESDSNKVCSLYSFRNNSTSPHKPEEGARERGDLLSSSAFGTPERRKGSLADVVDTLKQKKLEEMTKTEQDESSCMEKLLSKDWKEKMERLNTGELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQMEKQRQQMELARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGMSYKPGDNYPVQFIPSTMAAAAASGLNPLQLQQLYAAQLASMQVSPGAKMPPLPQPPNSAGQISPSGLKNEKRSSTPLAQVKEEGTQPLNLSARPKTAEPIKSPTSPTQSLFPGSKSSPNSLSKSGDIPSPIGGLGRGSSLDILSSLNSTALFGDQDAVMKAIQEARKMREQIQREQLQHHQQGMEVKLSALTSMGLNNCRTEKERSHYDNLGHHLSKLGEDGKIGHRVIDLTRPEDFEGGASTTEARVYREPRGRNSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMTNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIIDGKKLRISEYKQMMRSRRQEMRQFFTVGQQPQTQIPITTSAGVVYPGAITMATTTPSPHMTSDCSSASASPEPTIPVIQSTFNMKMEPGTMVPSDAVNGEDEMDMYEDFEDEPKSDYSSENDTHEPVSAN

Target ORF information:

RefSeq Version	NM_001123009.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio SRY-box transcription factor 6 (sox6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001123009.1

ORF Insert Sequence:

ATGTCTTCCA AGCAAGCCAC CTCTCCATTT ACCTCGACCC CTGATGGAGG TGAGGATGGA 
GTGAATCAGG AGCGTATGCC CTGGGAGAAG GAGGAGAACT CAGAGTCGCT AGTTGCCCCT 
CAGCTGCCCC TGCACAATCT GCTCCACAAC AAACCTCCCC TGGAGGAGCT CCAGCCAATC 
AGCAGCAGCG TGCCACCCGA ATCCGACTGG GACAGCCTGA TGTCAGCCCA GCAGCGCATG 
GAATCGGACA GCAATAAAGT ATGTTCCTTA TACTCCTTCC GGAATAACTC TACCTCTCCA 
CACAAGCCAG AGGAGGGGGC CAGGGAGCGT GGCGACCTGC TGAGCAGCTC AGCCTTCGGT 
ACGCCAGAAC GCCGCAAAGG AAGCCTGGCC GATGTGGTGG ACACACTGAA ACAGAAGAAA 
CTGGAGGAGA TGACAAAGAC AGAACAAGAC GAATCCTCCT GTATGGAGAA ACTCCTTTCT 
AAAGACTGGA AAGAGAAGAT GGAGCGACTG AACACTGGCG AGCTGTTAGG AGAAATTAAA 
GGTACTCCAG AAAGTCTTGC AGAGAAGGAG CGACAACTCT CCACCATGAT TACACAGCTC 
ATCAGTCTAC GAGAGCAGCT TCTGGCAGCC CATGATGAGC AGAAGAAACT GGCCGCCTCT 
CAGATGGAGA AACAGCGTCA GCAAATGGAG CTGGCACGCC AACAGCAAGA GCAGATCGCC 
AGACAACAGC AGCAACTTCT GCAGCAACAG CACAAAATCA ATCTCCTCCA GCAGCAGATT 
CAGGTCCAGG GTCACATGCC TCCGCTCATG ATCCCCATTT TTCCACACGA CCAGCGCACT 
CTGGCAGCAG CCGCAGCAGC TCAGCAGGGC TTCCTCTTCC CCCCAGGCAT GTCCTATAAG 
CCAGGTGATA ACTACCCGGT GCAGTTCATT CCATCCACAA TGGCAGCTGC TGCCGCGTCA 
GGACTCAACC CTCTCCAGCT CCAGCAACTC TACGCCGCCC AGCTGGCCAG CATGCAGGTC 
TCTCCAGGAG CCAAGATGCC TCCGCTGCCC CAGCCCCCCA ATTCTGCTGG GCAGATCTCC 
CCGTCTGGCT TGAAGAACGA GAAGAGGTCC TCAACCCCCC TGGCTCAAGT CAAGGAGGAG 
GGAACGCAGC CTCTCAACCT CTCCGCCCGG CCTAAAACAG CTGAGCCCAT CAAATCCCCC 
ACATCCCCGA CACAGAGCCT CTTCCCAGGC AGCAAGAGCA GCCCCAACAG CCTCTCCAAG 
AGCGGAGACA TACCCAGTCC CATCGGAGGA TTGGGCCGCG GCTCGTCTCT GGACATCCTG 
TCCAGCCTGA ACTCGACGGC GCTGTTTGGA GATCAGGACG CAGTGATGAA GGCCATCCAA 
GAGGCGAGGA AGATGAGAGA GCAGATTCAG AGAGAGCAGC TTCAGCATCA TCAGCAGGGA 
ATGGAGGTCA AGCTGTCTGC CCTCACCAGC ATGGGCTTGA ACAACTGCAG GACAGAGAAG 
GAGAGGTCTC ATTATGACAA TCTGGGTCAT CACTTGAGCA AACTTGGTGA AGATGGAAAG 
ATTGGTCATA GAGTCATTGA CCTCACCAGG CCAGAAGACT TTGAGGGAGG CGCCAGCACT 
ACCGAGGCAC GGGTCTACAG GGAACCCCGG GGAAGGAACA GCAACGAACC TCACATCAAA 
CGGCCCATGA ACGCCTTCAT GGTCTGGGCC AAAGATGAGC GCCGCAAAAT CCTTCAGGCC 
TTCCCAGACA TGCACAACTC CAACATCAGC AAAATCTTGG GATCTCGCTG GAAGTCTATG 
ACGAACCAGG AGAAACAACC GTATTACGAA GAGCAGGCAC GGCTCAGCAA GATCCACCTG 
GAGAAATACC CCAACTACAA GTACAAACCC AGACCCAAGC GCACCTGCAT CATCGACGGC 
AAGAAGTTGC GCATCAGCGA GTACAAGCAG ATGATGAGGT CACGGAGACA AGAGATGAGG 
CAGTTCTTCA CTGTGGGGCA GCAGCCACAG ACGCAGATCC CCATCACCAC CAGCGCAGGC 
GTTGTGTACC CGGGTGCCAT AACCATGGCC ACCACAACGC CATCCCCGCA CATGACGTCA 
GACTGCTCCA GTGCCTCGGC CAGCCCTGAA CCCACCATCC CCGTCATCCA GAGCACCTTC 
AACATGAAGA TGGAACCGGG TACCATGGTG CCCAGCGACG CAGTGAACGG AGAGGACGAG 
ATGGACATGT ACGAGGACTT TGAGGACGAG CCCAAATCGG ACTACAGCAG TGAGAATGAC 
ACACATGAGC CGGTCAGTGC CAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Copy Number Variation in SOX6 Contributes to Chicken Muscle Development.
Genes9(1)(2018 Jan)
Lin S,Lin X,Zhang Z,Jiang M,Rao Y,Nie Q,Zhang X

A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development.
eLife6(2017 08)
Ciarlo C,Kaufman CK,Kinikoglu B,Michael J,Yang S,D Amato C,Blokzijl-Franke S,den Hertog J,Schlaeger TM,Zhou Y,Liao E,Zon LI

Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle.
Cell reports17(9)2354-2366(2016 11)
Taglietti V,Maroli G,Cermenati S,Monteverde S,Ferrante A,Rossi G,Cossu G,Beltrame M,Messina G

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis.
Development (Cambridge, England)143(6)950-61(2016 Mar)
Leow SC,Poschmann J,Too PG,Yin J,Joseph R,McFarlane C,Dogra S,Shabbir A,Ingham PW,Prabhakar S,Leow MK,Lee YS,Ng KL,Chong YS,Gluckman PD,Stünkel W

Cartilage development requires the function of Estrogen-related receptor alpha that directly regulates sox9 expression in zebrafish.
Scientific reports518011(2015 Dec)
Kim YI,No Lee J,Bhandari S,Nam IK,Yoo KW,Kim SJ,Oh GS,Kim HJ,So HS,Choe SK,Park R

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sox6 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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